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Int J Public Health ; 66: 1604235, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34483811


Objectives: This study aimed to investigate the associations between air pollution exposure and pediatric outpatient visits for dry eye disease (DED) in Shenzhen, China. Methods: Generalized additive models were utilized to explore the acute effects of air pollution exposure on pediatric outpatient visits for DED. Results: Single-day lag exposures to NO2, O3, PM2.5, and PM10 were associated with DED outpatient visits at lag days 0, 6, 4 and 2. Relative risks (RRs) for DED given a 10-µg/m3 increase in NO2, O3, PM2.5, and PM10 concentrations were 1.062[95% confidence interval (CI) 1.003, 1.123], 1.015(95% CI 1.001, 1.031), 1.052(95% CI 1.001, 1.115), and 1.038 (95% CI 1.002, 1.076), respectively. RR for DED given a 10-µg/m3 increase in NO2 over cumulative lag days 0-1 was 1.075 (95% CI 1.009, 1.147), and RR for DED given a 10-µg/m3 increase in PM10 over cumulative lag days 0-4 was 1.051 (95% CI 1.003, 1.102). Conclusion: The observed associations between air pollution and outpatient visits for DED may provide evidence for policy makers to consider implementing measures to reduce the risk of DED owing to air pollution in China.

Poluição do Ar , Assistência Ambulatorial , Síndromes do Olho Seco , Exposição Ambiental , Poluição do Ar/efeitos adversos , Assistência Ambulatorial/estatística & dados numéricos , Criança , China/epidemiologia , Síndromes do Olho Seco/epidemiologia , Síndromes do Olho Seco/terapia , Exposição Ambiental/efeitos adversos , Exposição Ambiental/estatística & dados numéricos , Humanos
Int J Environ Health Res ; : 1-10, 2020 Aug 04.
Artigo em Inglês | MEDLINE | ID: mdl-32746628


This study aimed to assess the relationship between nitrogen dioxide (NO2) exposure and the risk of eye and adnexa diseases (EADs) among children in Shenzhen, China. Information about the daily number of outpatients with EADs and the concentration of air pollutants and meteorological data were collected. A generalized additive model was used to assess the effect of NO2 exposure on the risk of EADs during outpatient visits. An increase in NO2 level by 10 µg/m3 was related to an increase in the daily number of outpatients by 5.43% (95% confidence interval [CI]: 2.25%, 8.70%) at lag0, by 4.35% (95% CI: 1.15%, 7.66%) at lag1, and by 3.21% (95% CI: 0.05%, 6.47%) at lag3. In addition, the relationship between NO2 exposure and the risk of dacryoadenitis was the strongest, with an estimated value of 15.0% (95% CI: 7.99%, 22.5%) at lag0. Moreover, the association between NO2 exposure and the risk of EADs among children in Shenzhen was confirmed in this study. Therefore, the government should introduce stringent environmental policies to control air pollution and protect human health, particularly that of the vulnerable population.

Wei Sheng Yan Jiu ; 38(5): 579-81, 2009 Sep.
Artigo em Chinês | MEDLINE | ID: mdl-19877520


OBJECTIVE: to discuss the impact of different traffic crossroad exhaust pollution on the immune function of school-age children. METHODS: A school in the heavy traffic polluted area and B school in the less traffic polluted area were selected. Total 142 students from five to six grades in both areas were sampled. The level of peripheral blood cells (WBC, lymphocytes, neutral cells, red blood cells, platelets) and the T lymphocyte subpopulations (the percentages of CD3+, CD4+, CD8+ and the ratio of CD4+/CD8+), saliva lysozyme contents and immunoglobulin content were determined. RESULTS: Except for neutral cells, the peripheral blood cells level (WBC, lymphocytes, red blood cells, platelets) of children in the A school were higher than those in the B school. The contents of saliva lysozyme, immunoglobulin (IgG), T lymphocyte subpopulations (the percentages of CD3+, CD4+ and the ratio of CD4+/CD8+) in the A school were lower than those in the B school (P < 0.05). CONCLUSION: Exhaust pollution of different traffic crossroads could inhibit nonspecific immunity and cell immunity, and impact the level of blood cells and humoral immunity.

Poluentes Atmosféricos/efeitos adversos , Exposição Ambiental/efeitos adversos , Imunoglobulinas/sangue , Subpopulações de Linfócitos T/imunologia , Emissões de Veículos/análise , Criança , China , Cidades , Feminino , Humanos , Masculino , Muramidase/metabolismo , Saliva/metabolismo , Amostragem