Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 549
Filtrar
1.
Digit Health ; 6: 2055207620966860, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33294206

RESUMO

Introduction: On the world stage unlimited internet access by smartphones have made in social, cultural and economic relations, has transformed the world to be faster and more efficient. In this context, health care requires more attention. Health professionals must be concerned about the majority of the patient's care on the use of smartphone's in this process. Smartphones can be cause distractions and cause poor patient care. Behavioral and psychological changes related to abusive and uncontrolled use in this population may create severe impacts not only on the user's life but also on the community health care. Method: A careful research was performed through PubMed, Web of Science and Psycho Info databases using the terms: "Smartphone addiction", "Smartphone dependence", "Smartphone abuse", "physicians", "nurses" and ''health professionals". The search covered the past 5 years up to August 2019. Articles that examine abusive use on smartphones in health professionals were included. We analyzed how this concept evolved over the last five years and hope to contribute to the better understanding of the issue and its impacts on this population and on the health care. Results: There is a lack of specific trial instruments on screening of smartphone addiction or abusive use, tending to adopt different diagnostic criteria by the reports included. There are also a lack of studies discussing etiology of this compulsive behavior. Although known risks, published reports show there is no consciousness of abusive use and possible damages in healthcare by some health professionals. Instead, there are others that can affirm there are unpredictable risks in patient care and tend to stimulate conscience use politics in health settings. Most of them point out smartphone's app benefits. Conclusion: Smartphones and its functionalities became part of everyone's life by the various benefits guaranteed. However, an addictive behavior can cause damage, principally in the Health Care setting and health professional's abusive use must be monitored. Further investigation is needed to determine the motivations of this addictive behavior and if abusive smartphone usage is a new psychiatric classification or merely the substrate of other disorders.

3.
Psychiatr Danub ; 32(Suppl 1): 139-141, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32890377

RESUMO

In this brief report we present the case of a 53 year old man with a very debilitating Generalized Anxiety Disorder successfully treated with tranylcypromine. After several failed treatment attempts following international guidelines recommendations over the course of one year and a half, tranylcypromine was prescribed which led to effective and sustained remission of anxiety symptoms for this patient. We also briefly explore treatment options for resistant cases of generalized anxiety disorder, given the major negative impacts of untreated GAD in a person's daily functioning and quality of life.


Assuntos
Transtornos de Ansiedade , Inibidores da Monoaminoxidase , Qualidade de Vida , Ansiedade , Transtornos de Ansiedade/tratamento farmacológico , Quimioterapia Combinada , Humanos , Masculino , Pessoa de Meia-Idade , Inibidores da Monoaminoxidase/uso terapêutico
4.
Ear Hear ; 2020 Jul 02.
Artigo em Inglês | MEDLINE | ID: mdl-32639254

RESUMO

OBJECTIVES: Tinnitus is the perception of sound in ears or head without corresponding external stimulus. Despite the great amount of literature concerning tinnitus treatment, there are still no evidence-based established treatments for curing or for effectively reducing tinnitus intensity. Sham-controlled studies revealed beneficial effects using repetitive transcranial magnetic stimulation (rTMS). Still, results show moderate, temporary improvement and high individual variability. Subcallosal area (ventral and dorsomedial prefrontal and anterior cingulate cortices) has been implicated in tinnitus pathophysiology. Our objective is to evaluate the use of bilateral, high frequency, dorsomedial prefrontal cortex (DMPFC) rTMS in treatment of chronic subjective tinnitus. DESIGN: Randomized placebo-controlled, single-blinded clinical trial. Twenty sessions of bilateral, 10 Hz rTMS at 120% of resting motor threshold of extensor hallucis longus were applied over the DMPFC. Fourteen patients underwent sham rTMS and 15 were submitted to active stimulation. Tinnitus Handicap Inventory (THI), visual analog scale, and tinnitus loudness matching were obtained at baseline and on follow-up visits. The impact of intervention on outcome measures was evaluated using mixed-effects restricted maximum likelihood regression model for longitudinal data. RESULTS: A difference of 11.53 points in the THI score was found, favoring the intervention group (p = 0.05). The difference for tinnitus loudness matching was of 4.46 dB also favoring the intervention group (p = 0.09). CONCLUSIONS: Tinnitus treatment with high frequency, bilateral, DMPFC rTMS was effective in reducing tinnitus severity measured by THI and matched tinnitus loudness when compared to sham stimulation.

6.
J. bras. psiquiatr ; 69(1): 48-56, Jan.-Mar. 2020. tab, graf
Artigo em Português | LILACS-Express | LILACS | ID: biblio-1134934

RESUMO

RESUMO Objetivo Evidenciar os fatores predisponentes relativos à ansiedade em minorias sexuais e de gênero na literatura. Métodos Trata-se de uma revisão integrativa. A busca dos artigos foi realizada em três bases de dados eletrônicas: PubMed/Medline, Scopus e ISI Web of Knowledge . Foram utilizados os descritores " anxiety ", " LGBT people ", " gay ", " bisexual ", " lesbian " e " transgender ", com textos completos, publicados no período de 2013 a 2018, no idioma inglês, e foi usado o operador boleano AND . Resultados Foram encontrados 712 artigos. Cinquenta e oito (58) artigos foram selecionados para serem lidos na íntegra e 13 atenderam aos critérios de inclusão desta revisão. As evidências mostram que a população LGBT apresenta maior risco para transtornos mentais, entre eles a ansiedade, quando comparada aos heterossexuais. O aparecimento dos sinais e sintomas de ansiedade estão relacionados com a vergonha e o comportamento evitativo dessa população devido à forte discriminação e à ausência de apoio social e familiar, o que ocasiona altos níveis de angústia. Apenas dois artigos estudaram menores de 18 anos. Conclusões Os profissionais da saúde devem estar abertos, acolhedores e atentos à saúde mental desse público, visando contribuir com a promoção da saúde, apoio social, familiar e a redução da discriminação.


ABSTRACT Objective To evidence the predisposing factors related to anxiety in sexual and gender minorities in the literature. Methods This is an integrative review. The search of the articles was conducted in three databases: PubMed/Medline, Scopus and ISI Web of Knowledge. The descriptors "anxiety", "LGBT people", "gay", "bisexual", "lesbian" and "transgender" were used, with complete texts, published between 2013 and 2018, in the English language, boolean operator AND was used. Results A total of 712 articles were found. Fifty-eight (58) articles were selected to be read in their entirety and 13 met the inclusion criteria of this review. Evidence shows that LGBT people is at higher risk for mental disorders, including anxiety, when compared to heterosexual. The appearance of signs and symptoms of anxiety are related to shame and the avoidant behavior of this population due to the strong discrimination and lack of social and family life, which causes high levels of distress. Only two articles studied minors 18 years old. Conclusions Health professionals should be welcoming and attentive to health mental health of this public, with a view to contributing to health promotion, social and family support and reduction of discrimination.

7.
J Affect Disord ; 264: 498-505, 2020 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-31786029

RESUMO

BACKGROUND: Computer simulations (CS) and virtual reality exposure are promising techniques for research and treatment of panic disorder with agoraphobia (PDA). The objective of this study was to ascertain whether a given CS was a stimulus capable of producing panic attacks (PAs), anxiety and psychophysiological changes in patients with PDA. METHODS: Thirty PDA patients and 30 healthy subjects were recruited for this study. Subjects were exposed to a 3-min CS of a situation relevant to agoraphobic patients. Anxiety, panic symptoms, PAs, heart rate, skin conductance and respiration were recorded before, during and after the CS exposure. RESULTS: The CS effectively induced anxiety, hyperventilation and electrodermal responses in PDA patients but not in healthy subjects. Forty percent of PDA patients had a PA while none of the control subjects had a PA. A subgroup of patients who were less sensitive to the CS than the other subgroup of PDA patients and did not present full-blown PAs still had more panic symptoms, higher anxiety levels and more respiratory irregularities than the controls. LIMITATIONS: Low immersion and low sense of presence, lack of interaction with the environment. CONCLUSIONS: Exposure to the CS produced effects similar to in vivo exposure, respiratory and caffeine challenges. Subsequent studies should: make direct comparisons between CS and other challenges for PDA; investigate if CS can be a tool for predicting effects of medication; determine the potential of CS as a desensitization technique for situational PAs.

8.
Brain Behav ; 9(10): e01419, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31566935

RESUMO

BACKGROUND: Many patients with bipolar disorder (BD) fail to experience benefit following traditional pharmacotherapy, necessitating alternative treatment options that will enable such patients to achieve remission. Transcranial magnetic stimulation (TMS) is a relatively new, noninvasive neuromodulation technique that involves the application of magnetic pulses on hyperactive or hypoactive cortical brain areas. We evaluated the existing literature on TMS as a treatment for BD across varied mood states. METHODS: We searched PubMed up to October 2018 for original data articles published in English that evaluated outcomes in a bipolar sample across depressive, manic, mixed, and maintenance phases of BD. RESULTS: Clinical trials of TMS for BD particularly suggest the potential of repetitive TMS for reducing depressive symptoms. Studies of TMS for mania have yielded more mixed findings. Few studies have evaluated TMS in other phases of the bipolar illness. TMS is generally associated with mild side effects though, in a few studies, it has been shown to contribute to a manic switch in previously depressed bipolar patients. CONCLUSIONS: Transcranial magnetic stimulation is a promising approach for treating patients with BD who have failed to respond to pharmacological or psychosocial treatment. Future research should more clearly elucidate which TMS protocols may be most effective for a given bipolar patient.


Assuntos
Transtorno Bipolar/terapia , Estimulação Magnética Transcraniana/métodos , Humanos , Resultado do Tratamento
9.
Trends psychiatry psychother. (Impr.) ; 41(4): 401-408, Oct.-Dez. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1059184

RESUMO

Abstract Introduction Although bipolar disorder (BD) is traditionally included among mood disorders, some authors believe that changes in energy and motor activity, rather than mood changes, represent the true cardinal symptoms in mania and depression. The aim of the current study was to identify which cluster of the Hamilton Depression Rating Scale (HAM-D) better distinguishes between mania, depression and euthymia. Method A group of 106 patients with BD were followed for 13 years and repeatedly assessed with the HAM-D as well as with other clinical scales. To perform a comparison, HAM-D items were classified according to clinical criteria into three clusters: energy/activity symptoms, mood symptoms, and other symptoms. Item response theory (IRT) analyses were performed to provide a test information curve for those three clusters. We measured the prevalence of one cluster of symptoms over the other two throughout the latent trait. Results Considering HAM-D items individually, the IRT analysis revealed that there was a mixture of mood and energy/activity symptoms among the most discriminative items, both in depression and in euthymia. However, in mania, only energy/activity symptoms - i.e., general somatic symptoms and retardation - were among the most informative items. Considering the classification of items, both in depression as in mania, the energy/activity cluster was more informative than the mood cluster according to the IRT analysis. Conclusion Our data reinforce the view of hyperactivity and motor retardation as cardinal changes of mania and depression, respectively.


Resumo Introdução Embora o transtorno bipolar (TB) seja tradicionalmente incluído entre os transtornos do humor, alguns autores acreditam que as alterações na energia e na atividade motora, em vez das alterações no humor, representam os verdadeiros sintomas cardinais na mania e na depressão. O objetivo do presente estudo foi identificar qual grupo da Escala de Depressão de Hamilton (HAM-D) distingue melhor entre mania, depressão e eutimia. Método Um grupo de 106 pacientes com TB foram acompanhados por 13 anos e avaliados repetidamente com a HAM-D e com outras escalas clínicas. Para realizar uma comparação, os itens da HAM-D foram classificados de acordo com critérios clínicos em três grupos: sintomas de energia/atividade, sintomas de humor e outros sintomas. Foram realizadas análises da teoria da resposta ao item (TRI) para fornecer uma curva de informações de teste para esses três grupos. Medimos a prevalência de um grupo de sintomas em comparação aos outros dois através do traço latente. Resultados Considerando os itens da HAM-D individualmente, a análise da TRI revelou que havia uma mistura de sintomas de humor e de energia/atividade entre os itens mais discriminativos, tanto na depressão quanto na eutimia. No entanto, na mania, apenas os sintomas de energia/atividade - ou seja, sintomas somáticos gerais e retardo - estavam entre os itens mais informativos. Considerando a classificação dos itens, tanto na depressão quanto na mania, o grupo energia/atividade foi mais informativo que o grupo humor, de acordo com a análise da TRI. Conclusão Nossos dados reforçam a visão da hiperatividade e do retardo motor como as alterações cardinais de mania e depressão, respectivamente.


Assuntos
Humanos , Masculino , Feminino , Escalas de Graduação Psiquiátrica , Agitação Psicomotora/diagnóstico , Transtorno Bipolar/diagnóstico , Afeto , Depressão/diagnóstico , Agitação Psicomotora/psicologia , Transtorno Bipolar/psicologia , Depressão/psicologia , Entrevista Psicológica , Pessoa de Meia-Idade , Atividade Motora
10.
Trends psychiatry psychother. (Impr.) ; 41(4): 387-393, Oct.-Dez. 2019. tab
Artigo em Inglês | LILACS | ID: biblio-1059178

RESUMO

Abstract Objective To identify which clinical features and personality traits are associated with quality of life (QoL) in panic disorder (PD) patients. Methods This was a cross-sectional study with PD patients. The brief version of the World Health Organization Quality of Life Questionnaire (WHOQOL-BREF) and the Big Five Inventory (BFI) were used to assess QoL and personality traits respectively. The strength of correlations was measured with Pearson's, Spearman's, and point-biserial correlation coefficients. We also performed multiple linear regressions, considering sociodemographic data and scores from clinical scales as independent variables and QoL scores as dependent variables. Results A total of 98 patients were evaluated. Depressive symptoms had a strong negative correlation with QoL and, to a lesser extent, panic and anxiety symptoms were also negatively correlated with QoL. While consciousness, extraversion, and agreeableness had mild positive correlations with QoL, neuroticism had a strong negative correlation. Conclusion Symptoms of depression, anxiety, and panic seem to have a negative impact on the QoL of PD patients. Personality traits, especially neuroticism, may also influence QoL in these patients.


Resumo Objetivo Identificar quais características clínicas e traços de personalidade são mais associados à qualidade de vida (QdV) em pacientes com transtorno de pânico (TP). Métodos Este foi um estudo transversal, realizado em pacientes com TP. A versão breve do Questionário de Qualidade de Vida da Associação Mundial de Saúde (World Health Organization Quality of Life Questionnaire - WHOQOL-BREF) e o Inventário dos Cinco Grande Fatores (Big Five Inventory - BFI) foram utilizados para avaliar QdV e traços de personalidade, respectivamente. A força de associação foi medida através da correlação de Pearson, de Spearman ou ponto bisserial. Foram também realizadas regressões lineares múltiplas, considerando os dados sociodemográficos e escores obtidos nas escalas clínicas como variáveis independentes, e os escores de QdV como variáveis dependentes. Resultados Um total de 98 pacientes foram avaliados. Sintomas depressivos apresentaram uma forte relação negativa com QdV; em menor intensidade, sintomas de TP e ansiosos também se correlacionaram com QdV. Nos domínios de personalidade, enquanto conscienciosidade, extroversão e amabilidade apresentaram uma leve correlação positiva com QdV, neuroticismo apresentou forte correlação negativa. Conclusão Sintomas depressivos, ansiosos e de TP parecem ter forte impacto negativo na QdV dos pacientes com TP. Traços de personalidade, principalmente neuroticismo, podem influenciar QdV nesses pacientes.


Assuntos
Humanos , Masculino , Feminino , Adulto , Personalidade , Qualidade de Vida/psicologia , Transtorno de Pânico/psicologia , Inventário de Personalidade , Escalas de Graduação Psiquiátrica , Estudos Transversais , Inquéritos e Questionários
11.
Trends Psychiatry Psychother ; 41(2): 191-200, 2019 Jul 10.
Artigo em Inglês | MEDLINE | ID: mdl-31291413

RESUMO

INTRODUCTION: The objective of this study was to identify whether mixed states in bipolar disorder (BD) are associated with more frequent suicidal behavior when compared to manic/hypomanic and depressive episodes. METHOD: We performed a systematic search of the scientific literature on the subject using the PubMed, ISI Web Of Science, PsycINFO and SciELO databases. The terms chosen for the search were (bipolar) AND (suicid*) AND (mixed). We selected original studies comparing suicidal behavior of patients in mixed states and suicidal behavior of patients in other BD phases. RESULTS: Sixteen papers fit the selection criteria. Twelve of the original 16 studies compared suicidal behavior in mixed states and pure mania, and the majority of these studies (n = 11) revealed that suicidal behavior was more frequent among individuals in mixed states. Five of the papers compared suicidal behavior between depressive and mixed phases of BD. One of these five papers reported more severe suicidal behavior in patients in mixed states and another described more frequent suicidal behavior in patients with pure depression. There were no significant statistical differences between groups in the remaining three of these five studies. CONCLUSION: During acute BD episodes, suicidal behavior is more strongly associated with mixed states than with pure mania or hypomania. However, it was not possible to demonstrate that the association between suicidal behavior and mixed states is stronger than the association between suicidal behavior and depressive phases. The results hereby presented are worth considering in clinical practice to better evaluate suicide risk and to prevent suicide.


Assuntos
Transtorno Bipolar/psicologia , Ideação Suicida , Tentativa de Suicídio/psicologia , Humanos
13.
Expert Opin Pharmacother ; 20(14): 1743-1754, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31290333

RESUMO

Introduction: Persistent Depressive Disorder (PDD) is a nosological entity introduced with DSM-5, encompassing numerous different conditions including Dysthymia, recurrent Major Depressive Disorder, Double Depression and Chronic Major Depression. PDD is a particularly significant cause of disease burden in the general population. Areas covered: In the present paper, the authors explore the controversies surrounding the definition of PDD, the current approach to its treatment endorsed by the major scientific bodies, along with the available evidence on the efficacy of said treatments. Expert opinion: Clinicians need to be particularly vigilant and always gather a thorough history. In this diagnostic group, there is a relevant risk of having an undiagnosed Bipolar Disorder as affected individuals typically fail to recognize the pathological components of hypomanic episodes. In this setting, it is crucial to reconsider the diagnosis and to frequently verify compliance with the treatment plan. Numerous technological advances, particularly in the neuroimaging field, offer new insight and new challenges in defining the pathophysiological mechanisms of depressive syndromes. In the future, these advances may offer guidance towards an improved treatment approach and diagnostic process.


Assuntos
Antidepressivos/uso terapêutico , Transtorno Depressivo Maior/tratamento farmacológico , Transtorno Distímico/tratamento farmacológico , Amissulprida/uso terapêutico , Antipsicóticos/uso terapêutico , Transtorno Depressivo Maior/patologia , Transtorno Distímico/patologia , Humanos , Psicoterapia , Qualidade de Vida , Resultado do Tratamento
14.
Trends Psychiatry Psychother ; 41(2): 136-143, 2019 May 30.
Artigo em Inglês | MEDLINE | ID: mdl-31166564

RESUMO

OBJECTIVE: To assess the relationship between sexual hormones, sexual function and quality of life in postmenopausal women. METHOD: A cross-sectional study was conducted with a convenience sample of 36 postmenopausal women between the ages of 45 and 65 in follow-up at a climacteric outpatient clinic. Mood, quality of life, sexual function and hormonal profile were assessed. RESULTS: With regard to sexual hormones and sexual function, a relationship was found between orgasm and luteinizing hormone (r=0.37), orgasm and sex hormone-binding globulin (SHBG) (r=0.39), SHBG and less pain (r=0.44), dehydroepiandrosterone (DHEA) and desire (r=-0.45), as well as between prolactin and lubrication (r=0.33). Sexual hormones and quality of life were related as follows: progesterone and limitations due to physical aspects (r=0.35), SHBG and social aspects (r=0.35), cortisol and pain (r=0.46), DHEA and social aspects (r=-0.40). Finally, the following relationships were found between sexual function and quality of life: sexual desire and vitality, social aspects, state of general health and mental health (r=0.46, r=0.51, r=0.35, and r=0.38, respectively). Arousal, orgasm and satisfaction with sexual life showed a relationship with less physical pain (r=0.40, r=0.42, and r=0.43, respectively). Satisfaction with sexual life was correlated with vitality (r=0.33). CONCLUSION: Different correlations than expected were found in this study regarding the effect of some hormones on sexual function and some aspects of the quality of life of postmenopausal women.


Assuntos
Pós-Menopausa/sangue , Pós-Menopausa/psicologia , Qualidade de Vida/psicologia , Comportamento Sexual/psicologia , Idoso , Estudos Transversais , Desidroepiandrosterona/sangue , Feminino , Humanos , Hormônio Luteinizante/sangue , Pessoa de Meia-Idade , Orgasmo/fisiologia , Satisfação Pessoal , Progesterona/sangue , Globulina de Ligação a Hormônio Sexual/análise , Inquéritos e Questionários
15.
J. bras. psiquiatr ; 68(2): 110-120, abr.-jun. 2019. tab, graf
Artigo em Português | LILACS-Express | LILACS | ID: biblio-1019988

RESUMO

RESUMO Objetivo Revisar sistematicamente as informações disponíveis acerca da função sexual e/ou disfunção sexual em pacientes com transtorno depressivo maior (TDM) e/ou distimia (DIS). Métodos Foi realizada uma busca sistematizada na base eletrônica Medline por estudos que avaliavam a função/disfunção sexual em pacientes com TDM e DIS. Foram incluídos estudos publicados até junho de 2017. Artigos relevantes presentes nas referências dos artigos foram pesquisados manualmente e incluídos nesta revisão. Resultados Vinte estudos foram elegíveis para análise. Foi observada uma grande diversidade de resultados decorrente da heterogeneidade dos delineamentos empregados e devido aos diferentes métodos de avaliação utilizados. De forma geral, os dados provenientes demonstraram uma redução das principais funções sexuais em pacientes com TDM e DIS, tais como: libido (31%-32%), drive (31%-87%), excitação (29%-85%), ereção (18%-46%), lubrificação (18%-79%) e orgasmo (26%-81%). Aumento de libido (15%-22%) também foi descrito em alguns estudos. Conclusão A disfunção sexual é altamente prevalente na DIS e no TDM. Foram notadas diversas alterações de funcionamento sexual na população estudada. Discrepâncias acerca de suas prevalências podem ter ocorrido devido às variadas metodologias de análise utilizadas nos estudos.


ABSTRACT Objective To review the available data on the evaluation of sexual function and/or sexual dysfunction in patients with major depressive disorder (MDD) and/or Dysthymia (DYS) without pharmacological and psychotherapeutic treatment. Methods A systematic electronic search was conducted in the Medline database for studies that evaluated sexual function/dysfunction in patients with MDD and DYS. We included studies published up to June 2017. Relevant articles present in the articles references were manually searched and included in this review. Results Twenty studies were eligible for analysis. It was observed a variety of results due to the heterogeneity of the studies and due to the different evaluation methods used. In general, the data from these studies demonstrated a reduction of the main sexual functions in patients with MDD and DYS such as: libido (31%-32%), drive (31%-87%), arousal (29%-85%), erection (18%-46%), lubrication (18%-79%) and orgasm (26%-81%). Increased libido (15%-22%) has also been described in some studies. Conclusion Sexual dysfunction is highly prevalent in DYS and in MDD. Several sexual functioning alterations were observed in this study population. Prevalence discrepancies may have occurred due to the varied methodologies used in the studies.

16.
Trends psychiatry psychother. (Impr.) ; 41(2): 136-143, Apr.-June 2019. tab
Artigo em Inglês | LILACS | ID: biblio-1014737

RESUMO

Abstract Objective To assess the relationship between sexual hormones, sexual function and quality of life in postmenopausal women. Method A cross-sectional study was conducted with a convenience sample of 36 postmenopausal women between the ages of 45 and 65 in follow-up at a climacteric outpatient clinic. Mood, quality of life, sexual function and hormonal profile were assessed. Results With regard to sexual hormones and sexual function, a relationship was found between orgasm and luteinizing hormone (r=0.37), orgasm and sex hormone-binding globulin (SHBG) (r=0.39), SHBG and less pain (r=0.44), dehydroepiandrosterone (DHEA) and desire (r=-0.45), as well as between prolactin and lubrication (r=0.33). Sexual hormones and quality of life were related as follows: progesterone and limitations due to physical aspects (r=0.35), SHBG and social aspects (r=0.35), cortisol and pain (r=0.46), DHEA and social aspects (r=-0.40). Finally, the following relationships were found between sexual function and quality of life: sexual desire and vitality, social aspects, state of general health and mental health (r=0.46, r=0.51, r=0.35, and r=0.38, respectively). Arousal, orgasm and satisfaction with sexual life showed a relationship with less physical pain (r=0.40, r=0.42, and r=0.43, respectively). Satisfaction with sexual life was correlated with vitality (r=0.33). Conclusion Different correlations than expected were found in this study regarding the effect of some hormones on sexual function and some aspects of the quality of life of postmenopausal women.


Resumo Objetivo Avaliar a relação entre hormônios sexuais, função sexual e qualidade de vida em mulheres na pós-menopausa. Métodos Estudo transversal com amostra de conveniência de 36 mulheres na pós-menopausa, com idades entre 45 e 65 anos, em seguimento ambulatorial de climatério. Humor, qualidade de vida, função sexual e perfil hormonal foram avaliados. Resultados Entre hormônios sexuais e função sexual, foi encontrada relação entre orgasmo e hormônio luteinizante (r=0,37), orgasmo e globulina ligadora de hormônios sexuais (SHBG) (r=0,39), SHBG e menos dor (r=0,44), desidroepiandrosterona (DHEA) e desejo (r=-0,45), bem como entre prolactina e lubrificação (r=0,33). Entre hormônios sexuais e qualidade de vida: progesterona e limitações por aspectos físicos (r=0,35), SHBG e aspectos sociais (r=0,35), cortisol e dor (r=0,46), DHEA e aspectos sociais (r=-0,40). Por fim, entre função sexual e qualidade de vida: desejo sexual e vitalidade, aspectos sociais, estado geral de saúde e saúde mental (r=0,46, r=0,51, r=0,35 e r=0,38, respectivamente). Excitação, orgasmo e satisfação com a vida sexual mostraram uma relação com menos dor física (r=0,40, r=0,42 e r=0,43, respectivamente). A satisfação com a vida sexual foi correlacionada com a vitalidade (r=0,33). Conclusão Correlações diferentes das esperadas foram encontradas neste estudo em relação ao efeito de alguns hormônios sobre a função sexual e alguns aspectos da qualidade de vida de mulheres na pós-menopausa.


Assuntos
Humanos , Feminino , Idoso , Qualidade de Vida/psicologia , Comportamento Sexual/psicologia , Pós-Menopausa/psicologia , Pós-Menopausa/sangue , Orgasmo/fisiologia , Satisfação Pessoal , Progesterona/sangue , Globulina de Ligação a Hormônio Sexual/análise , Hormônio Luteinizante/sangue , Estudos Transversais , Inquéritos e Questionários , Desidroepiandrosterona/sangue , Pessoa de Meia-Idade
17.
Trends psychiatry psychother. (Impr.) ; 41(2): 191-200, Apr.-June 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1014739

RESUMO

Abstract Introduction The objective of this study was to identify whether mixed states in bipolar disorder (BD) are associated with more frequent suicidal behavior when compared to manic/hypomanic and depressive episodes. Method We performed a systematic search of the scientific literature on the subject using the PubMed, ISI Web Of Science, PsycINFO and SciELO databases. The terms chosen for the search were (bipolar) AND (suicid*) AND (mixed). We selected original studies comparing suicidal behavior of patients in mixed states and suicidal behavior of patients in other BD phases. Results Sixteen papers fit the selection criteria. Twelve of the original 16 studies compared suicidal behavior in mixed states and pure mania, and the majority of these studies (n = 11) revealed that suicidal behavior was more frequent among individuals in mixed states. Five of the papers compared suicidal behavior between depressive and mixed phases of BD. One of these five papers reported more severe suicidal behavior in patients in mixed states and another described more frequent suicidal behavior in patients with pure depression. There were no significant statistical differences between groups in the remaining three of these five studies. Conclusion During acute BD episodes, suicidal behavior is more strongly associated with mixed states than with pure mania or hypomania. However, it was not possible to demonstrate that the association between suicidal behavior and mixed states is stronger than the association between suicidal behavior and depressive phases. The results hereby presented are worth considering in clinical practice to better evaluate suicide risk and to prevent suicide.


Resumo Introdução Identificar se, no transtorno bipolar (TB), os estados mistos estão associados a um maior comportamento suicida, quando comparados a episódios maníacos/hipomaníacos e depressivos. Método Realizamos uma busca sistemática da literatura científica utilizando as bases de dados Pubmed, ISI Web of Science, PsycINFO e SciELO com os termos (bipolar) AND (suicid*) AND (mixed). Foram selecionados estudos originais que compararam o comportamento suicida entre pacientes em estado misto e pacientes em outras fases do TB. Resultados 16 artigos se adequaram aos critérios de seleção. Doze desses 16 estudos compararam estado misto com mania pura, e a maioria desses 12 estudos (n = 11) mostrou que o comportamento suicida era mais frequente entre os indivíduos em estado misto. Somente cinco dos artigos incluídos compararam o comportamento suicida entre as fases depressiva e mista do TB. Dentre esses cinco artigos, um mostrou maior comportamento suicida nos pacientes em estado misto, e um mostrou maior comportamento suicida nos pacientes com depressão pura. Em três desses cinco estudos, não houve diferença estatisticamente significativa entre os grupos. Conclusão Durante um episódio agudo do TB, os estados mistos estão mais relacionados ao comportamento suicida do que os episódios de mania ou hipomania puros. Todavia, não foi possível demonstrar que os estados mistos cursem com um maior risco de comportamento suicida do que os episódios depressivos puros. Os resultados aqui apresentados merecem ser considerados na prática clínica, a fim de avaliar melhor o risco de suicídio, bem como prevenir o suicídio.


Assuntos
Humanos , Tentativa de Suicídio/psicologia , Transtorno Bipolar/psicologia , Ideação Suicida
18.
Artigo em Inglês | MEDLINE | ID: mdl-31043997

RESUMO

Background: The aim was to assess the effects of a training program inclusive of contact sports and counseling on school dropout, quality of life (QoL) and psychopathologic symptoms in the youth with a history of school dropout and psychopathic personality traits. Methods: The Experimental Group (EG) consisted of 32 subjects (male 90.6%; age 19.6±4.3 years); the Control Group (CG) consisted of an equal number matched for gender and age with the same psychological features. At the beginning of the experimental Training Program (T0), both cohorts were assessed by a diagnostic psychiatric interview (SCID ANTAS), the Short Form Health Survey (SF-12) to evaluate QoL, the Psychopathy Checklist - Revised (PCL-R) for the assessment of psychopathic traits, the Self Reporting Questionnaire (SRQ) to measure general psychopathology. At the end of the program (T1), the coorths were evaluated by SF-12 and SRQ. Results: Twenty-seven subjects in the EG (84.4%) completed the course and underwent the evaluation at T1. The SF-12 score significantly increased from T0 to T1 in both groups, albeit this was more evident in the EG than in the CG, owing to an interaction between time and group. SRQ score significantly decreased in the EG from T0 to T1, while in the CG it did not, although the interaction between time and group was not significant. Conclusion: The experimental training program was effective in improving QoL and countering school dropout in young citizens with psychopathic traits. Further studies are needed to clarify if such results are due to a relationship between the practical tasks approach including contact sports and an improvement in mentalization processes.

19.
Eurasian J Med ; 51(1): 98-100, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30911267

RESUMO

We present a successful tinnitus treatment case with intensity and distress reduction in a patient subjected to bilateral 10 Hz repetitive transcranial magnetic stimulation (rTMS) to the dorsomedial prefrontal cortex (DMPFC). Subjective tinnitus is the perception of sound in the ears or head when no corresponding external stimulus exists. Approximately 1%-2% of the population report severe tinnitus with daily life impairment. Sham-controlled studies have revealed benefits using rTMS in tinnitus, although the improvement is moderate or temporary, indicating the need for new strategies. Evidence that the DMPFC is important in tinnitus pathophysiology makes this area a promising target. A 51-year-old male patient with a 4-year history of treatment-resistant moderate bilateral tinnitus was treated with 20 sessions of bilateral 10 Hz DMPFC rTMS. The patient showed important reduction and sustained 4-month response in tinnitus loudness and annoyance, 24 point drop in tinnitus handicap inventory, visual analog scale reduction to zero, and tinnitus loudness of 1 dB compared to baseline 15 dB. Tinnitus treatment is challenging and new alternatives are needed. To our knowledge, this is the first report using rTMS to the DMPFC for tinnitus. In this protocol, important and sustained reduction of tinnitus annoyance and loudness was obtained. This outcome of the case suggests that this approach is promising for treating tinnitus and is worth further investigation.

20.
Psychiatr Q ; 90(2): 385-394, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-30796694

RESUMO

Insight is greatly impaired in Bipolar Disorder (BD), especially during mania. Cognitive impairment is also present in BD. Despite that, few studies have investigated a possible association between these two aspects. The main goal of the current study is to compare BD affective states regarding performance in cognitive testing and investigate clinical and cognitive predictors for insight loss in BD. The study investigated a sample of 65 patients who were evaluated in one of the BD phases (mania, euthymia or depression). All the subjects underwent neuropsychological evaluation and completed the Insight Scale for Affective Disorders (ISAD). The relationship between level of insight and clinical/cognitive variables was analyzed through multiple regression models. No significant differences were found among BD phases regarding performance on cognitive testing. Insight was more impaired in mania then in depression or euthymia. Predictors for loss of insight were: severity of manic symptoms and impairments in selective attention (Symbol search test), divided attention (Trail making test) and inhibition (Stroop test). The sample size is a potential limitation of the current study. Nevertheless, the results suggest this had limited impact, with group differences being detected for a number of variables. The results found have important clinical importance, suggesting, for example, that rehabilitation of specific cognitive skills may improve insight in BD.


Assuntos
Conscientização/fisiologia , Transtorno Bipolar/fisiopatologia , Disfunção Cognitiva/fisiopatologia , Autoavaliação Diagnóstica , Adulto , Atenção/fisiologia , Transtorno Bipolar/complicações , Disfunção Cognitiva/etiologia , Função Executiva/fisiologia , Feminino , Humanos , Inibição Psicológica , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA