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1.
Mater Horiz ; 8(10): 2685-2708, 2021 Oct 04.
Artigo em Inglês | MEDLINE | ID: mdl-34605845

RESUMO

Chemical sensing is a strategic field of science and technology ultimately aiming at improving the quality of our lives and the sustainability of our Planet. Sensors bear a direct societal impact on well-being, which includes the quality and composition of the air we breathe, the water we drink, and the food we eat. Pristine low-dimensional materials are widely exploited as highly sensitive elements in chemical sensors, although they suffer from lack of intrinsic selectivity towards specific analytes. Here, we showcase the most recent strategies on the use of (supra)molecular interactions to harness the selectivity of suitably functionalized 0D, 1D, and 2D low-dimensional materials for chemical sensing. We discuss how the design and selection of receptors via machine learning and artificial intelligence hold a disruptive potential in chemical sensing, where selectivity is achieved by the design and high-throughput screening of large libraries of molecules exhibiting a set of affinity parameters that dictates the analyte specificity. We also discuss the importance of achieving selectivity along with other relevant characteristics in chemical sensing, such as high sensitivity, response speed, and reversibility, as milestones for true practical applications. Finally, for each distinct class of low-dimensional material, we present the most suitable functionalization strategies for their incorporation into efficient transducers for chemical sensing.

2.
Nutr Res Rev ; : 1-42, 2021 Oct 20.
Artigo em Inglês | MEDLINE | ID: mdl-34668465

RESUMO

Scientists are working to identify prevention/treatment methods and clinical outcomes of Coronavirus Disease 2019 (COVID-19). Nutritional status and diet have a major impact on the COVID-19 health-disease process, mainly due to the bidirectional interaction between gut-lung axis. Individuals with inadequate nutritional status have a pre-existing imbalance in the gut microbiota and immunity as seen in obesity, diabetes, hypertension, or other chronic diseases. Communication between the gut microbiota and lungs or other organs and systems may trigger worse clinical outcomes in viral respiratory infections. Thus, this review addresses new insights into the use of probiotics and prebiotics as a preventive nutritional strategy in managing respiratory infections such as COVID-19 and highlighting their anti-inflammatory effects against the main signs and symptoms associated with COVID-19. The search for studies was performed through Pubmed, Cochrane Library, Scopus, and Web of Science databases; relevant clinical articles were included. Significant randomized clinical trials suggest that specific probiotics and/or prebiotics reduce diarrhoea, abdominal pain, vomiting, headache, cough, sore throat, fever, and viral infection complications such as acute respiratory distress syndrome. These beneficial effects are linked with modulation of the microbiota, products of microbial metabolism with antiviral activity, and immune regulatory properties of specific probiotics and prebiotics through of Treg cell production and function. There is a need to conduct clinical and pre-clinical trials to assess the effect of consuming these components together with the current therapies in COVID-19.

3.
Sensors (Basel) ; 21(17)2021 Aug 24.
Artigo em Inglês | MEDLINE | ID: mdl-34502586

RESUMO

The aim of the study was to determine the between-match and between-halves match variability of various Global Positioning System (GPS) variables and metabolic power average (MPA) in competitions, based on the match results obtained by professional soccer players over a full season. Observations on individual match performance measures were undertaken on thirteen outfield players competing in the Iranian Premier League. The measures selected for analysis included total duration, accelerations in zones (AccZ1, 2, and 3), decelerations in zones (DecZ1, 2, and 3), and MPA collected by the Wearable Inertial Measurement Unit (WIMU). The GPS manufacturer set the thresholds for the variables analyzed as follows: AccZ1 (<2 m·s-2); AccZ2 (2 to 4 m·s-2); AccZ3 (>4 m·s-2); DecZ1 (<-2 m·s-2); DecZ2 (-2 to -4 m·s-2); DecZ3 (>-4 m·s-2). The results revealed significant differences between wins and draws for the duration of the match and draws compared to wins for the first- half duration (p ≤ 0.05; ES = 0.36 [-0.43, 1.12]), (p ≤ 0.05; ES = -7.0 [-8.78, -4.78], respectively. There were significant differences on AccZ1 during the first-half between draws and defeats (p ≤ 0.05; ES = -0.43 [-1.32, 0.46]), for AccZ3 in the second-half between draws and defeats (p ≤ 0.05; ES = 1.37 [0.48, 2.25]). In addition, there were significant differences between wins and draws (p ≤ 0.05; ES = 0.22 [-0.62, 1.10]), and wins and defeats for MPA in the first- half (p ≤ 0.05; ES = 0.34 [-0.65, 1.22]). MPA showed further differences between draws and defeats in the second- half (p ≤ 0.05; ES = 0.57 [-0.22, 1.35]). Descriptive analysis revealed differences between the first and second half for wins in AccZ2 (p = 0.005), DecZ2 (p = 0.029), and MPA (p = 0.048). In addition, draws showed significant differences between the first and second half in duration, AccZ1, AccZ2, and DecZ2 (p = 0.008), (p = 0.017), (p = 0.040), and (p = 0.037) respectively. Defeats showed differences between the first and second half in AccZ1, AccZ3, and MPA (p = 0.001), (p = 0.018), and (p = 0.003) respectively. In summary, the study reveals large variations between the match duration, accelerometer variables, and MPA both within and between matches. Regardless of the match outcome, the first half seems to produce greater outputs. The results should be considered when performing a half-time re-warm-up, as this may be an additional factor influencing the drop in the intensity markers in the second half in conjunction with factors such as fatigue, pacing strategies, and other contextual variables that may influence the results.


Assuntos
Desempenho Atlético , Corrida , Futebol , Aceleração , Sistemas de Informação Geográfica , Humanos , Irã (Geográfico) , Estações do Ano
4.
Glob Chang Biol ; 2021 Sep 03.
Artigo em Inglês | MEDLINE | ID: mdl-34478589

RESUMO

Droughts in a warming climate have become more common and more extreme, making understanding forest responses to water stress increasingly pressing. Analysis of water stress in trees has long focused on water potential in xylem and leaves, which influences stomatal closure and water flow through the soil-plant-atmosphere continuum. At the same time, changes of vegetation water content (VWC) are linked to a range of tree responses, including fluxes of water and carbon, mortality, flammability, and more. Unlike water potential, which requires demanding in situ measurements, VWC can be retrieved from remote sensing measurements, particularly at microwave frequencies using radar and radiometry. Here, we highlight key frontiers through which VWC has the potential to significantly increase our understanding of forest responses to water stress. To validate remote sensing observations of VWC at landscape scale and to better relate them to data assimilation model parameters, we introduce an ecosystem-scale analog of the pressure-volume curve, the non-linear relationship between average leaf or branch water potential and water content commonly used in plant hydraulics. The sources of variability in these ecosystem-scale pressure-volume curves and their relationship to forest response to water stress are discussed. We further show to what extent diel, seasonal, and decadal dynamics of VWC reflect variations in different processes relating the tree response to water stress. VWC can also be used for inferring belowground conditions-which are difficult to impossible to observe directly. Lastly, we discuss how a dedicated geostationary spaceborne observational system for VWC, when combined with existing datasets, can capture diel and seasonal water dynamics to advance the science and applications of global forest vulnerability to future droughts.

5.
Colloids Surf B Biointerfaces ; 208: 112118, 2021 Sep 16.
Artigo em Inglês | MEDLINE | ID: mdl-34547703

RESUMO

ß2 glycoprotein I (ß2GPI) is a soluble protein that participates in blood coagulation, clearance of apoptotic bodies and generation of antigens in antiphospholipid syndrome among many other functions. We studied the aggregates formed by ß2GPI with the anionic phospholipids palmitoyloleoylphosphatidyl glycerol, dimyristoylphosphatidyl glycerol, dipalmitoylphosphatidyl glycerol and cardiolipin using small angle X-ray scattering. The complexes obtained in a medium containing 0.01 M NaCl showed Bragg peaks up to the sixth order in a well-defined integer sequence indicating the presence of a lamellar stacking with a periodicity of 17.8 nm and with largely reduced membrane fluctuations. Modeling the complex signal allowed us to conclude that the coherence length was only two bilayers and that about 15% of the total surface was actually stacked. The space between bilayers allows accommodating an extended ß2GPI molecule making a bridge between the interacting bilayers. The interactions between membranes mediated by ß2GPI was favored when the membranes were in the liquid crystalline state.

6.
J Exp Bot ; 2021 Sep 21.
Artigo em Inglês | MEDLINE | ID: mdl-34545938

RESUMO

Addressing intraspecific variability of functional traits helps understand how climate change might influence the distribution of organismal traits across environments, but is notably understudied in the Amazon, especially for plant-hydraulic traits that are often used to project drought responses. We quantified intraspecific trait variability of leaf mass per area (LMA), wood density (WD) and hydraulic traits (xylem embolism resistance) for two dominant central-Amazonian tree species, along gradients of water and light availability, while accounting for tree age and height. Intraspecific variability in hydraulic traits (e.g., P50) was high, with within-species variability comparable to the whole-community variation. Hydraulic-trait variation was modulated mostly by the hydrological environment, with higher embolism resistance of trees growing on deep water table plateaus, as compared to shallow water table valleys. Intraspecific variability of LMA and WD was mostly modulated by intrinsic factors and light. The different environmental and intrinsic drivers of variation among and within-individuals lead to an uncoupled coordination among carbon acquisition/conservation and water use traits. Our findings suggest multivariate ecological strategies driving tropical tree distributions even within species, and reflect differential within-population sensitivities along environmental gradients. Therefore, intraspecific trait variability must be considered for accurate predictions of climate-change responses of tropical forests.

7.
J Bodyw Mov Ther ; 27: 628-633, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34391298

RESUMO

OBJECTIVE: To evaluate the effectiveness of an intervention with dual task based on trail making test on gait, cognition and daily activities execution in individuals with Parkinson's disease. DESIGN: Randomized controlled trial. METHODOLOGY: 10 individuals with Parkinson's Disease (PD) were divided into dual task group (DTG) and control group (CG). Were realized 16 dual task (DT) training sessions based on the Trail Making Test (TMT) for DTG and a conventional training protocol for CG. Pre and post intervention assessments used the 6 minute walk test (T6), TMT, Katz Index and Falls Efficacy Scale (FES). RESULTS: Comparing the difference between pre and post intervention values between groups, there was no significant difference for T6 (p=0,36). In TMT there was a significant difference (p=0,03), showing shorter times for DTG. The tests used for time values in the Katz index tasks showed an important difference for the DTG (P=0,02). As for the results of the FES, they did not show pre and post changes in the DTG (0,45) and in the CG (p= 0,29) and not even between the groups (p=0,45). CONCLUSION: The proposed intervention was able to promote improvements in the performance of daily life activities, learning adaptations and retention of motor and cognitive aspects, which may reflect positively in the daily lives of patients with PD and, consequently, greater autonomy to perform these types of activities.


Assuntos
Doença de Parkinson , Acidentes por Quedas , Cognição , Marcha , Humanos , Teste de Sequência Alfanumérica
8.
Ecol Lett ; 24(11): 2350-2363, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34409716

RESUMO

Hydraulic failure caused by severe drought contributes to aboveground dieback and whole-plant death. The extent to which dieback or whole-plant death can be predicted by plant hydraulic traits has rarely been tested among species with different leaf habits and/or growth forms. We investigated 19 hydraulic traits in 40 woody species in a tropical savanna and their potential correlations with drought response during an extreme drought event during the El Niño-Southern Oscillation in 2015. Plant hydraulic trait variation was partitioned substantially by leaf habit but not growth form along a trade-off axis between traits that support drought tolerance versus avoidance. Semi-deciduous species and shrubs had the highest branch dieback and top-kill (complete aboveground death) among the leaf habits or growth forms. Dieback and top-kill were well explained by combining hydraulic traits with leaf habit and growth form, suggesting integrating life history traits with hydraulic traits will yield better predictions.


Assuntos
Secas , Água , Hábitos , Folhas de Planta , Árvores
9.
Colloids Surf B Biointerfaces ; 207: 112027, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34388613

RESUMO

Purified myelin membranes (PMM) were spread as monomolecular films at the air/aqueous solution interface, and visualized by Brewster Angle Microscopy (BAM) at different lateral pressures (π) on three specific aqueous solutions: absence of salts, physiological conditions and presence of calcium. Coexistence of Liquid-Expanded (LE) and Liquid Ordered (LO) phases persisted up to collapse in the presence of salts, whereas monolayers became homogeneous at π ≥ 35-40 mN/m when salts are absent. This PMM phase-mixing behavior in monolayers is similar to the previously reported behavior of PMM multilamellar vesicles. Reflectivities (Rp) of p-polarized light from both phases were assessed throughout the whole π -range, and film thicknesses (t) were calculated from the Rp values and measured film refractive indices (n). The LO phase was found to be more reflective and thicker than the LE phase at π ≤ 15 mN/m, but less reflective and thinner at higher π. We also determined the line tension (λ) of PMM monolayers at the domain boundaries from the rate of domain shape relaxation, which turned out to be of the order of picoNewtons (pN) and decreased as π increased. A correlation between λ and thickness differences (Δt) was found, suggesting that Δt is a molecular determinant for λ in PMM monolayers. Both λ and Δt were found to increase markedly when calcium was present in the subphase. This result corroborates the concept of divalent cations as a stabilizing factor for phase separation, in line with earlier studies on this mixture forming multilamellar membrane arrangements.


Assuntos
Bainha de Mielina , Água , Microscopia , Pressão , Propriedades de Superfície
10.
Artigo em Inglês | MEDLINE | ID: mdl-34360295

RESUMO

The purpose of this study was to analyze the intragroup differences in weekly training monotony (TM) and training strain (TS) between starter and non-starter male professional soccer players at accelerometry based variables throughout the periods of a season. TM and TS of different accelerations and decelerations zones for twenty-one players were followed for forty-eight weeks. Regardless of group, players obtained the highest mean TM (starters = 3.3 ± 0.6, non-starters = 2.2 ± 1.1, in arbitrary unit, AU) and TS (starters = 1288.9 ± 265.2, non-starters = 765.4 ± 547.5, AU) scores in the pre-season for accelerations at Zone 1 (<2 m/s2). The results also indicated that both groups exhibited similar TM and TS scores in accelerations at Zones 2 (2 to 4 m/s2) and 3 (>4 m/s2) across the entire season. While the starters showed the highest TM and TS scores at deceleration Zone 1 (<-2 m/s2) in the end-season, the non-starters exhibited the highest scores at the deceleration Zone 1 in pre-season. It seems that in pre-season, coaches applied higher levels of training with greater emphasis on deceleration for non-starters. This tendency was reduced over time for non-starters, while starters presented higher values of deceleration Zone 1. These results highlight the variations in TM and TS across the different periods of a full season according to match starting status among professional soccer players, and the results suggest that non-starter players should receive higher levels of load to compensate for non-participation in matches throughout a soccer season.


Assuntos
Futebol , Dispositivos Eletrônicos Vestíveis , Aceleração , Acelerometria , Humanos , Masculino , Estações do Ano
11.
Medicina (Kaunas) ; 57(7)2021 Jun 23.
Artigo em Inglês | MEDLINE | ID: mdl-34201642

RESUMO

Background and Objectives: Interpretation of the load variations across a period seems important to control the weekly progression or variation of the load, or to identify in-micro- and mesocycle variations. Thus, the aims of this study were twofold: (a) to describe the in-season variations of training monotony, training strain and acute:chronic workload ratio (ACWR) through session ratings of perceived exertion (s-RPE), total distance and high-speed running (HSR); and (b) to compare those variations between starters and non-starters. Materials and Methods: Seventeen professional players from a European First League team participated in this study. They were divided in two groups: starters (n = 9) and non-starters (n = 8). The players were monitored daily over a 41-week period of competition where 52 matches occurred during the 2015-2016 in-season. Through the collection of s-RPE, total distance and HSR, training monotony, training strain and ACWR were calculated for each measure, respectively. Data were analyzed across ten mesocycles (M: 1 to 10). Repeated measures ANOVA was used with the Bonferroni post hoc test to compare M and player status. Results: The results revealed no differences between starters vs. non-starters (p > 0.05). M6 had a greater number of matches and displayed higher values for monotony (s-RPE, total distance and HSR), strain (only for total distance) and ACWR (s-RPE, TD and HSR). However, the variation patterns for all indexes displayed some differences. Conclusions: The values of both starters and non-starters showed small differences, thus suggesting that the adjustments of training workloads that had been applied over the season helped to reduce differences according to the player status. Even so, there were some variations over the season (microcycles and mesocycles) for the whole team. This study could be used as a reference for future coaches, staff and scientists.


Assuntos
Médicos , Corrida , Futebol , Humanos , Estações do Ano , Carga de Trabalho
12.
Artigo em Inglês | MEDLINE | ID: mdl-34199573

RESUMO

Soccer is a popular team sport and highly demanding activity that requires high effort and long-term training plans. The goals of this study were to compare the accelerations, decelerations and metabolic power between official and friendly full matches, between the first and second halves of the matches, and between both halves of official and friendly matches. Twelve professional soccer players (age, 28.6 ± 2.7 years; height, 182.1 ± 8.6 cm; body mass, 75.3 ± 8.2 kg; BMI, 22.6 ± 0.7 kg/m2) participated in this study. A total of 33 official and 10 friendly matches were analyzed from the Iranian Premier League. All matches were monitored using GPSPORTS systems Pty Ltd. The following variables were selected: total duration of the matches, metabolic power, accelerations Zone1 (<2 m·s-2) (AccZ1), accelerations Zone2 (2 to 4 m·s-2) (AccZ2), accelerations Zone3 (>4 m·s-2) (AccZ3), decelerations Zone1 (<-2 m·s-2) (DecZ1), decelerations Zone2 (-2 to -4 m·s-2) (DecZ2) and decelerations Zone3 (>-4 m·s-2) (DecZ3). The major finding was shown in metabolic power, where higher values occurred in friendly matches (p < 0.05 with small effect size). Furthermore, total duration, AccZ3, DecZ1, DecZ2, and DecZ3 were revealed to be higher in official matches, while AccZ1 and AccZ2 were higher in friendly matches. The second half of the official matches revealed higher values for total duration compared to friendly matches (p < 0.05, moderate effect size). In conclusion, this study observed higher values of metabolic power in friendly matches compared to official matches. AccZ3, DecZ1, DecZ2, and DecZ3 were higher in official matches, while AccZ1 and AccZ2 were higher in friendly matches.


Assuntos
Desempenho Atlético , Corrida , Futebol , Aceleração , Adulto , Desaceleração , Sistemas de Informação Geográfica , Humanos , Irã (Geográfico) , Estações do Ano
13.
Antimicrob Agents Chemother ; 65(9): e0090121, 2021 08 17.
Artigo em Inglês | MEDLINE | ID: mdl-34228534

RESUMO

Plasmodium falciparum multidrug resistance-1 gene (pfmdr1) polymorphisms associate with altered antimalarial susceptibility. Between 2010 and 2018/2019, we observed that the prevalence of the wild-type allele N86 and the wild-type combination NYD increased 10-fold (4% versus 40%) and more than 2-fold (18% versus 44%), respectively. Haplotypes other than NYD or NFD declined by up to >90%. Our molecular data suggest the pfmdr1 pattern shifted toward one associated with artemether-lumefantrine resistance.


Assuntos
Antimaláricos , Artemisininas , Malária Falciparum , Proteínas Associadas à Resistência a Múltiplos Medicamentos , Antimaláricos/farmacologia , Antimaláricos/uso terapêutico , Artemeter/uso terapêutico , Combinação Arteméter e Lumefantrina , Artemisininas/farmacologia , Artemisininas/uso terapêutico , Resistência a Medicamentos/genética , Humanos , Malária Falciparum/tratamento farmacológico , Proteínas Associadas à Resistência a Múltiplos Medicamentos/genética , Plasmodium falciparum/genética , Polimorfismo Genético/genética , Ruanda
14.
FEBS J ; 2021 Jul 29.
Artigo em Inglês | MEDLINE | ID: mdl-34327848

RESUMO

There are several examples of single mutations that lead to a well-defined disease through a well-known mechanism. In other cases, a collection of mutations of the same protein produces a pathology with different degrees of severity. The accompanying work by Uusitalo et al. studies several mutants of the fatty acid binding protein P2 of the peripheral nervous system myelin. They conserve the native tertiary structure but a remarkable difference in the capacity to interact with lipids. This could be a clue to unravel the complex way in which these mutations affect myelin structure and function in a variant of Charcot-Marie-Tooth disease. Comment on: https://doi.org/10.1111/febs.16079.

15.
Environ Monit Assess ; 193(8): 531, 2021 Jul 28.
Artigo em Inglês | MEDLINE | ID: mdl-34322768

RESUMO

Multivariate calibration based on partial least squares, random forest, and support vector machine methods, combined with the MissForest imputation algorithm, was used to understand the interaction between ozone and nitrogen oxides, carbon monoxide, wind speed, solar radiation, temperature, relative humidity, and others, the data of which were collected by air quality monitoring stations in the metropolitan area of Rio de Janeiro in four distinct sites between, 2014 and, 2018. These techniques provide an easy and feasible way of modeling and analyzing air pollutants and can be used when coupled with other methods. The results showed that random forest and support vector machine chemometric techniques can be used in modeling and predicting tropospheric ozone concentrations, with a coefficient of determination for making predictions up to 0.92, a root-mean square error of calibration between 4.66 and 27.15 µg m-3, and a root-mean square error of prediction between 4.17 and 22.45 µg m-3, depending on the air quality monitoring stations and season.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Ozônio , Poluentes Atmosféricos/análise , Poluição do Ar/análise , Brasil , Calibragem , Monitoramento Ambiental , Ozônio/análise
16.
Glycobiology ; 2021 Jun 29.
Artigo em Inglês | MEDLINE | ID: mdl-34192330

RESUMO

Leishmania (L.) amazonensis is one of the species responsible for the development of cutaneous leishmaniasis in South America. After entering the vertebrate host, L. (L.) amazonensis invades mainly neutrophils, macrophages, and dendritic cells. Studies have shown that gal-3 acts as a pattern recognition receptor. However, the role of this protein in the context of L. (L.) amazonensis infection remains unclear. Here, we investigated the impact of gal-3 expression on experimental infection by L. (L.) amazonensis. Our data showed that gal-3 plays a role in controlling parasite invasion, replication and the formation of endocytic vesicles. Moreover, mice with gal-3 deficiency showed an exacerbated inflammatory response. Taken together, our data shed light to a critical role of gal-3 in the host response to infection by L. (L.) amazonensis.

18.
J Fish Biol ; 99(4): 1274-1279, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34159594

RESUMO

Cylindrospermopsin (CYN) is a cyanotoxin that has raised serious concerns about public health in many parts of the world. It can bioaccumulate and affect the health of aquatic organisms, but despite this, few studies have been conducted on CYN uptake and clearance in fish. In this paper, the authors evaluate the uptake and clearance of CYN in the muscle tissue and viscera of juvenile tilapia (Oreochromis niloticus) after exposure to aqueous extracts and whole cells of Cylindrospermopsis raciborskii (CYN-producer). CYN blended with commercial fish food, and three experiments were conducted. In the first trial, fish food, and aqueous extracts containing 0.31 µg CYN g-1 of food per day, was administered to tilapia for 15 days. In the second trial, fish were provided food and intact cells (5.4 µg CYN g-1 of food per day) for 15 days. In the last trial, they were provided fish food and aqueous extracts (0.8 µg CYN g-1 of food per day) for 12 days, and for the next 10 days, the animals were fed food without toxic cell extracts (to simulate a clearance period). The concentration of CYN in muscle tissue and viscera was analysed using ELISA. In the case of juvenile tilapia, the presence of CYN was higher in viscera than in muscle tissue, and the toxin remained in the tissues even after 10 days without the addition of contaminated food. The results suggest that tilapia represents a potential source of CYN transfer through the food web, and this shows the need for a continuous monitoring of this compound in organisms that are used for human and animal consumption.


Assuntos
Ciclídeos , Alcaloides , Animais , Cylindrospermopsis , Laboratórios , Uracila
20.
Artigo em Inglês | MEDLINE | ID: mdl-34069032

RESUMO

BACKGROUND: The purpose of this study is to compare training load (TL) preceding a home versus away match in a top-class elite European team during the 2015-2016 season. METHODS: Twenty elite outfield soccer players with a mean ± SD age, height and body mass of 25.9 ± 4.6 years, 183.1 ± 6.6 cm and 78.6 ± 6.6 kg, respectively, participated in this study. Total distance covered, high-speed running distance (HSRD), average speed (AvS), rating of perceived exertion (RPE) multiplied by training duration (s-RPE) and Hooper index (HI) were collected. Data from 24 weeks were analyzed through match-day minus/plus approach (MD-5, -4, -3, -2, -1, MD + 1). RESULTS: All external TL variables indicated a decrease from MD-5 until MD-1 and then an increase to MD + 1 (p < 0.01). HI decreased from MD-5 to MD-1, but s-RPE increased until MD-3 and then decreased until MD + 1. When comparing TL data that preceded home matches versus away matches, for MD-5, HSRD and muscle soreness exhibited higher values when away match neared (p < 0.05). For MD-4 and MD-3, total distance, HSRD and AvS exhibited higher values closer to an away match than a home match (p < 0.05). For MD-1, total distances covered were higher closer to a home match than an away match (p < 0.01). For MD + 1, all HI items and AvS were higher when an away match was played (p < 0.05). CONCLUSIONS: This study confirms and provides evidence regarding the influence on internal and external TL data preceding home and away matches from a team that played in European competitions.


Assuntos
Futebol , Adulto , Humanos , Mialgia , Esforço Físico , Estações do Ano , Adulto Jovem
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