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1.
Rev. lab. clín ; 12(4): 179-188, oct.-dic. 2019. ilus, tab, mapas, graf
Artigo em Espanhol | LILACS-Express | ID: ibc-ET1-4190

RESUMO

La alergia al látex es una respuesta alterada de nuestro organismo al contactar con las proteínas que se encuentran en el látex de caucho natural. Los síntomas de la hipersensibilidad alérgica al látex son bastante parecidos a los de la alergia a los alimentos, siendo menos frecuentes los síntomas digestivos y más típicos los cutáneos tras el uso de guantes de látex, y los nasales y/o el asma tras la inhalación del polvo de los guantes de látex o de los globos. En caso de pacientes muy sensibles puede provocar reacciones alérgicas graves si entra en contacto con mucosas o cavidades internas. Se da la paradoja de que el medio hospitalario, es el lugar de más riesgo dada la cantidad existente de látex, tanto directo como indirecto. Las personas alérgicas al látex presentan a menudo reacciones alérgicas cruzadas, a veces graves, tras ingerir determinadas frutas y vegetales. Las reacciones cruzadas se deben a los alérgenos comunes presentes en el látex y en los diferentes alimentos. Es importante utilizar el análisis molecular de alérgenos para detectar falsos diagnósticos a látex por problemas de reactividad cruzada con proteínas de frutas. Indicamos cómo estas nuevas pruebas han sustituido a análisis menos precisos y eficientes, logrando un considerable ahorro de recursos


Latex allergy is an altered response of the body on contact with proteins found in natural rubber latex. The symptoms of allergic hypersensitivity to latex are quite similar to those of food allergy, with the gastrointestinal symptoms being less frequent and the cutaneous ones being more typical after the use of latex and nasal gloves and / or the asthma after the inhalation of the dust from latex gloves or balloons. In the case of very sensitive patients it can cause severe allergic reactions if it comes in contact with mucous membranes or internal cavities. There is a paradox that the hospital environment is the most risky place, given the existing amount of latex in direct and indirect use. People who are allergic to latex often have cross-allergic reactions, sometimes severe, after eating certain fruits and vegetables. The cross-reactions are due to the common allergens present in latex and in different foods. It is important to use molecular allergen analysis to detect false latex diagnoses due to problems of cross-reactivity with fruit proteins. It is indicated how these new tests have replaced less accurate and efficient analyses, achieving a considerable saving of resources

2.
Biochem Pharmacol ; : 113649, 2019 Oct 03.
Artigo em Inglês | MEDLINE | ID: mdl-31586588

RESUMO

BACKGROUND: Nutrition is a key factor in determining exercise response. The aim of this review is to assess the response to exercise in older adults who take supplements of antioxidants and/or omega-3 polyunsaturated fatty acids. METHODS: A systematic literature search was performed (June 2009- September 2019) in MEDLINE via Pubmed. The following search strategy was used with Boolean markers: ("omega-3 fatty acids" [Major] OR "antioxidants" [Major]) AND "exercise" AND "aged" [MesH]. Fourteen articles were finally included. RESULTS: Exercise-induced free radical and inflammatory marker blood levels, but not changed the plasma total antioxidant capacity (TAC), after administration of antioxidant supplement. The oral administration of antioxidants produced null or negative effect on endothelial function, but the infusion into the brachial artery during rhythmic handgrip exercise produced a significant improvement in muscle blood flow, due to an on increase in the availability of nitric acid derived from the nitric oxide synthase. Aerobic exercise and antioxidant supplementation improved submaximal and maximal aerobic parameters, as well as mitochondrial density and mitochondria-regulated apoptotic signaling. Antioxidant supplementation, but not omega-3 PUFA, decreased pro-inflammatory marker levels and fat oxidation induced by exercise. Strength training decreased serum B12 concentration but combined with omega-3 PUFA or antioxidant supplementation, B12 levels were maintained. Antioxidant supplementation has protective effect after fatigue in isometric exercise but improved appendicular fat-free mass just combined with resistance exercise. Omega-3 fatty acid supplement combined with exercise increased lean mass in women, but not in men. Muscle damage induced by exercise is protected by antioxidant supplementation. CONCLUSIONS: Older people who take antioxidant and/or omega-3 PUFA supplements showed improved exercise response, as well as lower muscle damage.

3.
Curr Pharm Des ; 25(15): 1783-1790, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31267857

RESUMO

BACKGROUND: Several drugs have been currently approved for the treatment of obesity. The pharmacokinetic of liraglutide, as well as the treatment of type 2 diabetes mellitus, have been widely described. OBJECTIVE: To analyze the published systematic reviews on the use of liraglutide for the treatment of obesity. METHODS: Systematic reviews were found out through MEDLINE searches, through EBSCO host and the Cochrane Library based on the following terms: "liraglutide" as major term and using the following Medical Subject Headings (MesH) terms: "obesity", "overweight", "weight loss". A total of 3 systematic reviews were finally included to be analyzed. RESULTS: From the three systematic reviews selected, only two included the randomized clinical trials, while the third study reviewed both randomized and non-randomized clinical trials. Only one review performed statistical tests of heterogeneity and a meta-analysis, combining the results of individual studies. Another review showed the results of individual studies with odds ratio and confidence interval, but a second one just showed the means and confidence intervals. In all studies, weight loss was registered in persons treated with liraglutide in a dose dependent form, reaching a plateau at 3.0 mg dose, which was reached just in men. Most usual adverse events were gastrointestinal. CONCLUSION: More powerful and prospective studies are needed to assess all aspects related to liraglutide in the overweight and obesity treatment.

4.
Curr Pharm Des ; 25(16): 1889-1912, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31267859

RESUMO

BACKGROUND: Antioxidant supplementation has become a common practice among athletes to theoretically achieve a reduction in oxidative stress, promote recovery and improve performance. OBJECTIVE: To assess the effect of antioxidant supplements on exercise. METHODS: A systematic literature search was performed up to January 2019 in MEDLINE via EBSCO and Pubmed, and in Web of Sciences based on the following terms: "antioxidants" [Major] AND "exercise" AND "adaptation"; "antioxidant supplement" AND "(exercise or physical activity)" AND "(adaptation or adjustment)" [MesH]. Thirty-six articles were finally included. RESULTS: Exhaustive exercise induces an antioxidant response in neutrophils through an increase in antioxidant enzymes, and antioxidant low-level supplementation does not block this adaptive cellular response. Supplementation with antioxidants appears to decrease oxidative damage blocking cell-signaling pathways associated with muscle hypertrophy. However, upregulation of endogenous antioxidant enzymes after resistance training is blocked by exogenous antioxidant supplementation. Supplementation with antioxidants does not affect the performance improvement induced by resistance exercise. The effects of antioxidant supplementation on physical performance and redox status may vary depending on baseline levels. CONCLUSION: The antioxidant response to exercise has two components: At the time of stress and adaptation through genetic modulation processes in front of persistent pro-oxidant situation. Acute administration of antioxidants immediately before or during an exercise session can have beneficial effects, such as a delay in the onset of fatigue and a reduction in the recovery period. Chronic administration of antioxidant supplements may impair exercise adaptations, and is only beneficial in subjects with low basal levels of antioxidants.

6.
Nutr Hosp ; 34(5): 1424-1431, 2017 Nov 14.
Artigo em Espanhol | MEDLINE | ID: mdl-29280660

RESUMO

AIMS: To assess, using a posterioritechniques, prevailing food consumption patterns of university students in Zamora and their association with food groups, in order to know how far can be away from a healthy diet, such as the Mediterranean diet. METHODS: Cross-sectional, descriptive and observational study of a representative sample of university students in the province of Zamora (n = 213, 18-29 years). Food consumption was assessed using a validated semi-quantitative consumer frequency questionnaire, which included 64 foods, grouped into 13 food groups. Consumption patterns were determined by factor analysis. RESULTS: University students in Zamora show two consumption patterns: "Mediterranean", which accounts for 19.4% of the total variance and is characterized by consumption of dairy products, fish and seafood, meats and vegetables, sausages, cereals and tubers, fruit and vegetables and olive oil, and "Western", which accounts for 22.2% of the total variance and is characterized by consumption of dairy products, eggs, meats and vegetables, sausages, nuts, other fats other than olive oil, pastries and sweets, prepared foods and sugar sweetened beverages, with low consumption of fruit and vegetables. The factor analysis shows a sample adequacy measure (KMO) of 0.615. CONCLUSIONS: The university students of Zamora are in nutritional transition, with a diet that moves away from the recommendations of the Mediterranean Diet.


Assuntos
Ingestão de Alimentos , Estudantes/estatística & dados numéricos , Adolescente , Adulto , Inquéritos sobre Dietas , Dieta Mediterrânea , Exercício , Comportamento Alimentar , Feminino , Humanos , Masculino , Espanha/epidemiologia , Universidades , Adulto Jovem
7.
Nutr. hosp ; 34(6): 1424-1431, nov.-dic. 2017. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-168984

RESUMO

Objetivos: analizar, mediante técnicas a posteriori, los principales patrones de consumo de alimentos de los estudiantes universitarios de Zamora y su asociación con los diferentes grupos de alimentos, para así conocer cuánto se alejan de las recomendaciones de una dieta saludable, como es la dieta mediterránea. Métodos: estudio transversal, descriptivo y observacional sobre una muestra representativa de los estudiantes universitarios de la provincia de Zamora (n = 213; 18-29 años). El consumo de alimentos se determinó mediante un cuestionario validado semicuantitativo de frecuencia de consumo, que incluía 64 alimentos, reunidos en 13 grupos. Los patrones de consumo se determinaron por análisis factorial. Resultados: los estudiantes universitarios de Zamora muestran dos patrones de consumo: mediterráneo, que explica un 19,4% de la varianza total y se caracteriza por un consumo de lácteos, pescado y mariscos, carnes y legumbres, embutidos, cereales y tubérculos, fruta y verduras y aceite de oliva; y occidental, que explica un 22,2% de la varianza total y se caracteriza por un consumo de lácteos, huevos, carnes y legumbres, embutidos, frutos secos, otras grasas distintas del aceite de oliva, bollería y dulces, alimentos preparados y bebidas azucaradas, con bajo consumo de fruta y verduras. El análisis factorial presenta una medida de adecuación de la muestra (KMO) de 0,615. Conclusiones: los estudiantes universitarios de Zamora se encuentran en transición nutricional, con una dieta que se aleja de las recomendaciones de la dieta mediterránea (AU)


Aims: To assess, using a posteriori techniques, prevailing food consumption patterns of university students in Zamora and their association with food groups, in order to know how far can be away from a healthy diet, such as the Mediterranean diet. Methods: Cross-sectional, descriptive and observational study of a representative sample of university students in the province of Zamora (n = 213, 18-29 years). Food consumption was assessed using a validated semi-quantitative consumer frequency questionnaire, which included 64 foods, grouped into 13 food groups. Consumption patterns were determined by factor analysis. Results: University students in Zamora show two consumption patterns: «Mediterranean», which accounts for 19.4% of the total variance and is characterized by consumption of dairy products, fish and seafood, meats and vegetables, sausages, cereals and tubers, fruit and vegetables and olive oil, and “Western”, which accounts for 22.2% of the total variance and is characterized by consumption of dairy products, eggs, meats and vegetables, sausages, nuts, other fats other than olive oil, pastries and sweets, prepared foods and sugar sweetened beverages, with low consumption of fruit and vegetables. The factor analysis shows a sample adequacy measure (KMO) of 0.615. Conclusions: The university students of Zamora are in nutritional transition, with a diet that moves away from the recommendations of the Mediterranean Diet (AU)


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto Jovem , Adulto , Consumo de Alimentos/normas , Estudantes/estatística & dados numéricos , Dieta Mediterrânea , Transição Nutricional , Dieta Ocidental , Exercício/fisiologia , Estado Nutricional/fisiologia , Estudos Transversais/estatística & dados numéricos , Inquéritos e Questionários , Análise Fatorial , Declaração de Helsinki , Antropometria/instrumentação , Análise Estatística
8.
Enferm Clin ; 18(4): 201-4, 2008.
Artigo em Espanhol | MEDLINE | ID: mdl-18724917

RESUMO

OBJECTIVE: To identify which factors motivate nurses with more than 10 years' experience in the ICU of the Hospital General Universitario de Alicante to stay in the unit and to analyze the reasons for leaving in nurses who left this ICU after more than 10 years. METHOD: We performed a descriptive, observational, cross-sectional study. Thirty-two nurses who had worked in the ICU for more than 10 years completed a written questionnaire. In the 18 nurses that had left the ICU, the reasons for leaving were determined. The results are expressed in relative frequencies and percentages. RESULTS: Twenty nurses (62%) continued to work in the ICU because they liked the service and five (16%) because they had not been able to work in a position they liked more. Of the nurses who had left the ICU after 10 or more years, 67% had done so to work on a fixed shift. CONCLUSIONS: Most of the nurses who had worked for more than 10 years in the ICU stayed because they liked the service, while most of those who left did so to work fixed shifts.


Assuntos
Unidades de Terapia Intensiva , Recursos Humanos de Enfermagem no Hospital , Reorganização de Recursos Humanos/estatística & dados numéricos , Adulto , Estudos Transversais , Humanos , Pessoa de Meia-Idade , Fatores de Tempo , Recursos Humanos
9.
Enferm. clín. (Ed. impr.) ; 18(4): 201-204, jul. 2008. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-67133

RESUMO

Objetivos. Identificar qué factores motivan a las enfermeras con más de 10 años de experiencia en la Unidad de Cuidados Intensivos (UCI) del Hospital General Universitario de Alicante a continuar en ella y analizar, en las enfermeras que se trasladaron desde esta UCI tras más de 10 años, las causas que motivaron ésta decisión. Método. Estudio descriptivo, observacional y transversal. Treinta y dos enfermeras de UCI con más de 10 años de antigüedad en ella cumplimentaron un cuestionario escrito; para 18 enfermeras que se habían trasladado de UCI tras más de 10 años en ella, se determinaron sus características y el motivo que las llevó a solicitar el traslado. Los resultados se expresan en frecuencias relativas y porcentajes. Resultados. El 62% de las enfermeras (20) continuaban en la UCI porque les gustaba el servicio y el 16% (5) por nohaber podido salir a un puesto que les gustase más. El 67% de las enfermeras que se habían trasladado tras 10 años o más de ejercicio en la UCI lo había hecho por trabajar en un turno fijo. Conclusiones. La mayoría de las enfermeras con más de 10 años de antigüedad en UCI continúa en ella porque les gusta el servicio; la mayor parte de las enfermeras que salieron de UCI tras más de 10 años lo hizo para trabajar en un turno fijo


Objective. To identify which factors motivate nurses with more than 10 years’ experience in the ICU of the Hospital General Universitario de Alicante to stay in the unit and to analyze the reasons for leaving in nurses who left this ICU after more than 10 years.Method. We performed a descriptive, observational, cross-sectional study. Thirty-two nurses who had worked in theICU for more than 10 years completed a written questionnaire. In the 18 nurses that had left the ICU, the reasons for leaving were determined. The results are expressed in relative frequencies and percentages.Results. Twenty nurses (62%) continued to work in the ICU because they liked the service and five (16%) becausethey had not been able to work in a position they liked more. Of the nurses who had left the ICU after 10 or moreyears, 67% had done so to work on a fixed shift.Conclusions. Most of the nurses who had worked for more than 10 years in the ICU stayed because they liked theservice, while most of those who left did so to work fixed shifts


Assuntos
Humanos , Cuidados de Enfermagem/estatística & dados numéricos , Unidades de Terapia Intensiva , Satisfação no Emprego , Carga de Trabalho/estatística & dados numéricos , Jornada de Trabalho em Turnos , Condições de Trabalho
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