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1.
Int J Biol Macromol ; 133: 722-731, 2019 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-31002903

RESUMO

The objectives of this study were i) to microencapsulate probiotic cells of Lactobacillus plantarum through a dual process consisting of emulsification followed by complex coacervation using gelatin and gum arabic, ii) to characterize the lyophilized microcapsules, iii) to evaluate their behavior in simulated in vitro gastrointestinal conditions and iv) to evaluate the survival of microencapsulated probiotic cells during 45 days of storage at 8 °C, 25 °C and -18 °C. The optimized conditions for complex coacervation consisted of a 50:50 biopolymer ratio and pH = 4.0. Emulsification was followed by complex coacervation using gelatin and gum arabic. The microcapsules presented dispersibility of 0.183 ±â€¯0.17 g·mL-1, moisture content of 4.5%, water activity of 0.34 ±â€¯0.03 and hygroscopicity of 9.20 ±â€¯0.43 g of absorbed water per 100 g. Their size ranged from 66.07 ±â€¯3.04 µm to 105.66 ±â€¯3.24 µm. Viability of the encapsulated L. plantarum cells was 8.6 log CFU·g-1 and the encapsulation efficiency was 97.78%. After in vitro simulation of gastrointestinal conditions, viability of the encapsulated cells was 80.4% whereas it was only 25.0% for the free cells at 37 °C. Probiotic cell viability was maintained during storage at 8 °C and - 18 °C for 45 days.

2.
ACM arq. catarin. med ; 42(2): 56-61, abr.-jun. 2013. Tab, Graf
Artigo em Português | LILACS-Express | ID: biblio-393

RESUMO

A assistência pré-natal (APN) é uma importante estratégia de redução da morbimortalidade materna e perinatal. Mas para cumprir seus objetivos necessita estar bem estruturada. Para avaliar o processo de APN prestada às usuárias do sistema público no município de Chapecó-SC, realizou-se estudo transversal com análise de prontuário de gestantes de baixo risco que realizaram o atendimento entre 1° julho de 2009 a 31 de julho de 2010. Foram coletados dados referentes à história médica, vacinação, hábitos de vida, e estrutura das consultas. A avaliação da adequação da APN foi feita com base nos critérios propostos pelo Programa Nacional de Humanização do Parto e Nascimento e foi classificado em três níveis de complexidade, sendo por fim classificada em três categorias: adequado, intermediário e inadequado. A população-alvo foi de 160 mulheres, sendo que 80 entraram no estudo. Destas, 85% realizaram no mínimo seis consultas, e 70% realizaram a primeira consulta antes de 14 semanas de gestação. A taxa de realização dos exames laboratoriais foi alta, e o número mínimo de procedimentos clínico-obstétricos foi adequado para a maioria. Cerca de 70% das gestantes tinham imunização para tétano. A partir disso, observamos que no nível de maior complexidade, 25% das gestantes receberam atendimento adequado, 46,3%, intermediário e 28,8%, inadequado. Conclui- -se que o processo de assistência prestada às usuárias foi considerado satisfatório em relação à utilização do pré-natal, porém houve uma falha da adequação quando adicionados procedimentos laboratoriais e clínico-obstétricos, demonstrando necessidade de ajustes do processo de APN para que seus reais objetivos sejam alcançados.


The prenatal care (PNC) is an important strategy of reducing the maternal and perinatal morbimortality. However, in order to fulfill its objectives, it needs to be very well organized. To evaluate the PNC process given to public healthcare users in the district of Chapecó-SC, it was done a transversal study analyzing low-risk expectant mothers' medical records who have received attendance between July 1st, 2009 and July 31st, 2010. It was collected data regarding medical history, vaccination, lifestyle and consultation methods. The PNC adequation evaluation was done based on criteria proposed by the National Program for the Humanization of Labor and Birth and was classified in three levels of complexity, therefore denominated three categories: adequate, intermediary and inadequate. The target population was 160 women, 80 of whom participated in the study. From these, 85% attended at least six medical appointments and 70% attended the first consultation before 14 weeks of gestation. The realization of laboratory tests was high and the minimum number of clinical and obstetrical procedures was adequate to the majority of them. Around 70% of the expectant mothers showed immunization to tetanus. From that, it was observed that within the biggest complexity level, 25% of the expectants received adequate medical attendance, 46.3%, intermediary and 28.8%, inadequate. It is concluded that the assistance process to the users was satisfactory regarding the prenatal care utilization. There was a flaw in the adequation, however, when adding the clinical and obstetrical laboratory procedures to the process, showing the need of improvement in the PNC process in order for it to reach its real goals.

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