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1.
Braz Oral Res ; 30(1): e115, 2016 Nov 28.
Artigo em Inglês | MEDLINE | ID: mdl-27901199

RESUMO

This study aimed to perform a systematic review and meta-analysis to evaluate the effectiveness of chlorhexidine varnish on the reduction of caries incidence during fixed orthodontic treatment. The literature searches involved The Cochrane Library, Medline, Scopus, OpenSigle databases and manual searches. The search on OpenSigle did not produce any additional articles. Clinical studies conducted in patients with orthodontic fixed appliances that used professional application of chlorhexidine varnish were included. The effect-size was calculated and a meta-analysis was performed. From 182 abstracts, a total of six articles fulfilled the inclusion criteria. After reading the full articles, one was excluded because of lack of a control group. Three articles were used for continuous data analysis, and two articles were used for the dichotomous data analysis. The pooled meta-analysis with continuous data demonstrated chlorhexidine varnish effectiveness on caries reduction (p = 0.003), with a mean difference and confidence interval of -1.49 [-2.47, -0.51]. On the basis of the pooled meta-analysis of continuous data, we were able to conclude that professional application of chlorhexidine varnish is effective in caries incidence reduction during fixed orthodontic treatment.


Assuntos
Anti-Infecciosos Locais/uso terapêutico , Cariostáticos/uso terapêutico , Clorexidina/uso terapêutico , Cárie Dentária/prevenção & controle , Aparelhos Ortodônticos/microbiologia , Adolescente , Criança , Feminino , Humanos , Masculino , Reprodutibilidade dos Testes , Resultado do Tratamento
2.
Braz. oral res. (Online) ; 30(1): e115, 2016. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-951950

RESUMO

Abstract This study aimed to perform a systematic review and meta-analysis to evaluate the effectiveness of chlorhexidine varnish on the reduction of caries incidence during fixed orthodontic treatment. The literature searches involved The Cochrane Library, Medline, Scopus, OpenSigle databases and manual searches. The search on OpenSigle did not produce any additional articles. Clinical studies conducted in patients with orthodontic fixed appliances that used professional application of chlorhexidine varnish were included. The effect-size was calculated and a meta-analysis was performed. From 182 abstracts, a total of six articles fulfilled the inclusion criteria. After reading the full articles, one was excluded because of lack of a control group. Three articles were used for continuous data analysis, and two articles were used for the dichotomous data analysis. The pooled meta-analysis with continuous data demonstrated chlorhexidine varnish effectiveness on caries reduction (p = 0.003), with a mean difference and confidence interval of −1.49 [−2.47, −0.51]. On the basis of the pooled meta-analysis of continuous data, we were able to conclude that professional application of chlorhexidine varnish is effective in caries incidence reduction during fixed orthodontic treatment.

3.
Braz. dent. j ; 24(5): 537-541, Sep-Oct/2013. tab, graf
Artigo em Inglês | LILACS | ID: lil-697630

RESUMO

Mucocele is a benign lesion occurring in the buccal mucosa as a result of the rupture of a salivary gland duct and consequent outpouring of mucin into soft tissue. It is usually caused by a local trauma, although in many cases the etiology is uncertain. Mucocele is more commonly found in children and young adults, and the most frequent site is the lower inner portion of the lips. Fibroma, on the other hand, is a benign tumor of fibrous connective tissue that can be considered a reactionary connective tissue hyperplasia in response to trauma and irritation. They usually present hard consistency, are nodular and asymptomatic, with a similar color to the mucosa, sessile base, smooth surface, located in the buccal mucosa along the line of occlusion, tongue and lip mucosa. Conventional treatment for both lesions is conservative surgical excision. Recurrence rate is low for fibroma and high for oral mucoceles. This report presents a series of cases of mucocele and fibroma treated by surgical excision or enucleation and the respective follow-up routine in the dental clinic and discusses the features to be considered in order to distinguish these lesions from each other.


Mucocele é uma lesão comum na mucosa bucal, que resulta da ruptura de um ducto de glândula salivar e consequente derramamento de mucina para o interior dos tecidos moles circunjacentes. Frequentemente este derrame resulta de trauma local, embora em muitos casos a etiologia seja indefinida. É uma lesão não infecciosa benigna, que frequentemente afeta a cavidade bucal de crianças e adultos jovens, localizando-se geralmente na porção interna dos lábios inferiores. Por outro lado, o fibroma é um tipo de tumor benigno do tecido conjuntivo fibroso que pode ser considerado uma hiperplasia reacional do tecido conjuntivo em resposta a traumas e irritação. Geralmente são nodulares, com consistência firme, assintomáticos, coloração semelhante à da mucosa, base séssil, superfície lisa, localizados na mucosa jugal ao longo da linha de oclusão, língua e mucosa labial. O tratamento convencional para ambas as lesões é a excisão cirúrgica conservadora, sendo que sua recorrência é rara para fibromas e alta para as mucoceles. Este trabalho relata casos clínicos de mucocele e fibroma, tratados pela técnica de excisão cirúrgica ou enucleação, bem como descreve a proservação no consultório odontológico. As características importantes para o diagnóstico diferencial dessas lesões são discutidas.


Assuntos
Adulto , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Fibroma/diagnóstico , Fibroma/cirurgia , Mucocele/diagnóstico , Mucocele/cirurgia , Diagnóstico Diferencial , Fibroma/patologia , Mucocele/patologia
4.
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-601371

RESUMO

A agenesia dentária consiste em uma anomalia comum de desenvolvimento, que resulta na alteração do número de dentes preentes na cavidade bucal e afeta aproximadamente 20% da população. Sua etiologia está associada a fatores ambientais, como infecções, traumas, quimioterapia, radioterapia e causas genéticas. Atualmente a etiologia mais aceita para explicar a ocorrência das anomalias dentárias é a alteração na expressão de genes específicos. Com base no conhecimento dos genes e fatores de transcrição envolvidos na odontogênese, presume-se que diferentes formas fenotípicas de agenesia dentária são causadas por mutações em diferentes genes. Os genes envolvidos na agenesia dentária em humanos incluem os fatores de transcrição (MSX1 e PAX9) que desempenham um papel crítico durante o desenvolvimento craniofacial e o gene que codifica uma proteína envolvida na via de sinalização canônica Wnt (AXIN2). Dessa maneira, a proposta do presente estudo é discorrer sobre os principais genes que têm sido relatados como reguladores da formação dental e a ocorrência de mutações nestes genes que poderiam resultar em agenesias dentárias


Dental agenesis is a common developmental anomaly which affects approximately 20% of the population and results in a reduction of number of teeth present in the oral cavity. The etiology is associated with environmental factors, such as infections, trauma, chemotherapy, radiotherapy, and genetic causes. Currently the widely accepted theory to explain the occurrence of dental agenesis is the change in the expression of specific genes. Different phenotypic patterns of dental agenesis are caused by mutations in genes and transcription factors involved in odontogenesis. In humans those genes include transcription factors (MSX1 and PAX9) that play a critical role during development and the gene coding for a protein involved in the canonical Wnt signaling (AXIN2). Therefore, the purpose of this study is to discuss about dental agenesis and the key genes that have been reported as regulators of dental formation and how the occurrence of mutations in these genes could result in dental agenesis


Assuntos
Proteínas Wnt , Fator de Transcrição MSX1 , Fator de Transcrição PAX9 , Anodontia , Mutação
5.
RPG rev. pos-grad ; 18(2): 79-82, abr.-jun. 2011. graf
Artigo em Inglês | LILACS | ID: lil-679844

RESUMO

The goal of this research was to assess whether there was a change in the profile of dental procedures performed in the Pediatric Dental Clinic at the School of Dentistry of Ribeirão Preto at University of São Paulo during the period between the years 1980 to 2004. Using the dental records of 3,484 pediatric patients attended at the Pediatric Dental Clinic, we conducted a survey of clinical procedures performed by undergraduate students in the years 1980, 1984, 1988, 1992, 1996, 2000 and 2004. The following procedures, performed in deciduous and permanent teeth in children from 1 to 12 years, were: topicalapplications of fluoride, pit and fissure sealant applications, silver amalgam and composite resin fillings, pulpotomy and tooth extraction. The numeric values obtained for each procedure were converted into percentages, and data were analyzed using Fisher Exact or qui-square tests (α = 0.05). The results revealed the occurrence of a significant increase (p < 0.01) in percentage of topical fluoride applications (increase of 18.9%) and sealants applications (increase of 11.2%). On the other hand, the percentage of performance of silver amalgam and composite resin fillings, pulpotomies and tooth extraction showed a significant decline of 16.0, 6.0 and 16.1%, respectively (p < 0.05). It can be concluded that there was a decline of restorative, surgical and conservative endodontic procedures, with a concomitant increase of preventive procedures.


Assuntos
Humanos , Masculino , Feminino , Lactente , Pré-Escolar , Criança , Fissuras Dentárias , Restauração Dentária Permanente , Endodontia , Odontopediatria , Selantes de Fossas e Fissuras , Pulpotomia , Fluoreto de Sódio , Extração Dentária , Dente Decíduo
6.
RPG rev. pos-grad ; 18(1): 8-12, Jan.-Mar. 2011. tab
Artigo em Inglês | LILACS | ID: lil-679731

RESUMO

The objective of this study was to evaluate the efficacy of three spray antimicrobial solutions for the disinfection of childrenÆs toothbrushes. A 4-stage changeover system was used. The solutions studied were: BrushtoxTM (Spray 1), CosmocilTM + basic formula (Spray 2), basic formula (Spray 3), and control û sterile water (Spray 4). Forty children used the solutions in all stages. In each stage, the children received a new toothbrush and performed a single 1-min brushing. Thereafter, the solutions were sprayed six times at different positions on the toothbrush bristles. After four hours, microbiologic culture of the toothbrushes was performed. BrushtoxTM, CosmocilTM + basic formula, and basic formula presented a similar effect on prevention of cariogenic biofilm formation which was better than basic formula alone or sterile water. BrushtoxTM showed the best antimicrobial efficacy.


Assuntos
Humanos , Masculino , Feminino , Criança , Biofilmes , Dispositivos para o Cuidado Bucal Domiciliar , Desinfecção , Sprays Orais , Escovação Dentária
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