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PLoS One ; 15(6): e0234490, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32555613


Classical swine fever (CSF) is an infectious viral disease caused by an RNA virus belonging to the Pestivirus genus. A total of 134 outbreaks of CSF have occurred in the last seven years in the North of Colombia. The objective of this study was the characterization of the herds affected by CSF from 2013 to 2018. Most of the outbreaks (95%) occured in backyard piggeries. The principal causes of transmission of CSF were the introduction of infected pigs (38%), movements of people (37%) and unknown origin (13%). The epidemiological relationships with 15 affected farms explained 31 outbreaks. The overall attack and mortality rates were 39% and 32%, respectively. The main clinical signs were high fever (67%), incoordination of movements (54%), and prostration (52%). Seventy-three percent of the herds had not been vaccinated against CSF and 17% had been only partially vaccinated. A spatio-temporal analysis, using a Poisson regression model, revealed two clusters with high risk; the first and largest one from 2014 to 2016 had a relative risk (RR) of 13.4 and included part of the departments of Atlántico, Bolívar, Cesar, La Guajira, Norte de Santander, Magdalena and Sucre; and the second cluster (RR = 9.6 in 2016) included municipalities in the north of the department of Cordoba.

Peste Suína Clássica/epidemiologia , Surtos de Doenças/veterinária , Animais , Colômbia , Fazendas/estatística & dados numéricos , Fatores de Risco , Análise Espaço-Temporal , Suínos
BMC Vet Res ; 15(1): 81, 2019 Mar 07.
Artigo em Inglês | MEDLINE | ID: mdl-30845954


BACKGROUND: Bovine brucellosis is a zoonotic disease that causes substantial economic losses and has a strong impact on public health. The main objective of this paper is to determine the risk factors for new infections of Brucella abortus on Colombian cattle farms previously certified as being free of brucellosis. A case-control study was conducted by comparing 98 cases (farms certified as brucellosis-free for three or more years but became infected) with 93 controls (farms that remained brucellosis-free during at least the previous three years). The farms were matched by herd size and geographical location (municipality). Information was obtained via a questionnaire completed by veterinary officers through a personal interview with the herd owners. RESULTS: Two-thirds of the herds (67%) were dairy herds, 16% were beef herds, and 17% were dual-purpose (beef and milk) herds. After exploratory univariate analysis, all explanatory variables with a p-value of ≤0.20 were included in a logistic regression model using the forward stepwise method to select the model with the best goodness of fit. The significant risk factors were the replacement of animals from farms not certified as brucellosis-free compared to replacement from certified brucellosis-free farms (OR = 4.84, p-value < 0.001) and beef cattle farms compared to dairy cattle farms (OR = 3.61, p-value = 0.017). When herds with and without artificial insemination were compared, it was observed that farms that used natural breeding with bulls from non-certified herds had a higher risk than farms using artificial insemination (OR = 2.45, p-value = 0.037), but when the bulls came from brucellosis-free farms, farms with natural breeding were less affected (OR = 0.30, p-value = 0.004) than farms using artificial insemination, whether with frozen semen from certified brucellosis-free herds or fresh semen from uncontrolled herds. The latter is commonly sold to neighbouring farms. CONCLUSIONS: The government should make efforts to inform farmers about the risks involved in the introduction of semen and replacement heifers from farms that are not certified as brucellosis-free and to establish measures to control these practices.

Brucelose Bovina/epidemiologia , Brucelose Bovina/prevenção & controle , Criação de Animais Domésticos/normas , Animais , Cruzamento/métodos , Brucella abortus/isolamento & purificação , Brucelose Bovina/transmissão , Bovinos , Colômbia/epidemiologia , Criopreservação , Indústria de Laticínios , Feminino , Inseminação Artificial/métodos , Inseminação Artificial/veterinária , Masculino , Fatores de Risco , Preservação do Sêmen
Sci Rep ; 8(1): 4479, 2018 03 14.
Artigo em Inglês | MEDLINE | ID: mdl-29540734


HIV infection has a tremendous impact on the immune system's proper functioning. The mucosa-associated lymphoid tissue (MALT) is significantly disarrayed during HIV infection. Compositional changes in the gut microbiota might contribute to the mucosal barrier disruption, and consequently to microbial translocation. We performed an observational, cross-sectional study aimed at evaluating changes in the fecal microbiota of HIV-infected individuals from Colombia. We analyzed the fecal microbiota of 37 individuals via 16S rRNA gene sequencing; 25 HIV-infected patients and 12 control (non-infected) individuals, which were similar in body mass index, age, gender balance and socioeconomic status. To the best of our knowledge, no such studies have been conducted in Latin American countries. Given its compositional nature, microbiota data were normalized and transformed using Aitchison's Centered Log-Ratio. Overall, a change in the network structure in HIV-infected patients was revealed by using the SPIEC-EASI MB tool. Genera such as Blautia, Dorea, Yersinia, Escherichia-Shigella complex, Staphylococcus, and Bacteroides were highly relevant in HIV-infected individuals. Differential abundance analysis by both sparse Partial Least Square-Discriminant Analysis and Random Forest identified a greater abundance of Lachnospiraceae-OTU69, Blautia, Dorea, Roseburia, and Erysipelotrichaceae in HIV-infected individuals. We show here, for the first time, a predominantly Lachnospiraceae-based signature in HIV-infected individuals.

Clostridiaceae , Fezes/microbiologia , Microbioma Gastrointestinal , Infecções por HIV/epidemiologia , Adolescente , Adulto , Biodiversidade , Estudos de Casos e Controles , Clostridiaceae/classificação , Clostridiaceae/genética , Colômbia/epidemiologia , Feminino , Infecções por HIV/diagnóstico , Infecções por HIV/imunologia , Infecções por HIV/virologia , Humanos , Masculino , Metagenoma , Metagenômica/métodos , Pessoa de Meia-Idade , RNA Ribossômico 16S/genética , Índice de Gravidade de Doença , Adulto Jovem
Front Psychol ; 8: 1423, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28871234


Emotional attention has been found as a key predictive dimension of stress. However, very few studies have investigated the relationship between emotional attention and test anxiety. The objective of the present study was to analyze the role of emotional attention, measured using the Trait Meta-Mood Scale (TMMS), on the level of test anxiety, and measured using the Test Anxiety Inventory (TAI). In addition, we examined the potential mediating role of Self-Rumination and Self-Reflection, as measured through the Rumination-Reflection Questionnaire (RRQ), on the relationship between emotional attention and test anxiety. The sample included 385 Spanish adolescents between 14 and 19 years of age. Mediation analysis results are consistent with a model in which Self-Rumination, but no Self-Reflection, mediates the relationship between Emotional Attention and Test Anxiety. Finally, several potential implications of these findings to improve quality of life in adolescents are discussed.

Arch Esp Urol ; 70(2): 304-306, 2017 Mar.
Artigo em Espanhol | MEDLINE | ID: mdl-28300035


OBJECTIVE: We present an unusual case of emphysematous cystitis with multiple septic embolisms to several organs. METHOD AND RESULTS: Case description and selection of related pictures. Review of the existing literature. CONCLUSIONS: Emphysematous cystitis is a rare condition but potentially severe. Prognosis depends on a rapid diagnosis and treatment.

Cistite/microbiologia , Embolia Aérea/microbiologia , Enfisema/microbiologia , Infecções por Escherichia coli , Idoso , Infecções por Escherichia coli/diagnóstico , Infecções por Escherichia coli/terapia , Feminino , Humanos
Arch. esp. urol. (Ed. impr.) ; 70(2): 304-306, mar. 2017. ilus
Artigo em Espanhol | IBECS | ID: ibc-160973


OBJETIVO: Presentamos un raro caso de cistitis enfisematosa con embolismo séptico gaseoso en múltiples órganos. MÉTODO Y RESULTADO: Descripción de caso clínico y aportación de iconografía. Revisión de la literatura relacionada. CONCLUSIONES: La cistitis enfisematosa es una condición rara, aunque potencialmente grave cuyo pronóstico depende de un rápido diagnóstico y tratamiento

OBJECTIVE: We present an unusual case of emphysematous cystitis with multiple septic embolisms to several organs. METHOD AND RESULTS: Case description and selection of related pictures. Review of the existing literature. CONCLUSIONS: Emphysematous cystitis is a rare condition but potentially severe. Prognosis depends on a rapid diagnosis and treatment

Humanos , Feminino , Idoso , Cistite/complicações , Cistite/diagnóstico , Cistite/terapia , Enfisema/complicações , Prognóstico , Derrame Pleural/complicações , Antibacterianos/uso terapêutico , Embolia Aérea/patologia , Embolia Aérea , Insuficiência de Múltiplos Órgãos/complicações , Glicosúria/urina , Cetose/urina , Insuficiência Respiratória/complicações , Comorbidade , Abdome/patologia , Abdome
Coluna/Columna ; 15(3): 238-240, July-Sept. 2016. graf
Artigo em Inglês | LILACS | ID: lil-795009


ABSTRACT Objectives: To determine the standard of treatment of degenerative lumbar spondylolisthesis in its different clinical presentations in UMAE Dr. Victorio de la Fuente Narváez. Methods: Six cases found in the literature were presented to 36 experts in spine surgery, along with treatment options, to thereby obtain a standard prescription for the treatment of degenerative lumbar spondylolisthesis. Analytical observational cross-sectional descriptive study. Results: It was found that the treatment of choice in cases of degenerative lumbar spondylolisthesis with axial symptoms is conservative. The surgical treatment of choice for both stable and unstable patients with radiculopathy and/or claudication is decompression + posterolateral graft + transpedicular instrumentation + discectomy (graft). Conclusions: We managed to define the degenerative lumbar spondylolisthesis treatment guidelines in our unit, which can serve as a basis for the development of a clinical practice guide.

RESUMO Objetivos: Determinar o padrão de tratamento de espondilolistese lombar degenerativa em suas diversas apresentações clínicas em UMAE Dr. Victorio de la Fuente Narváez. Métodos: Seis casos encontrados na literatura foram apresentados a 36 médicos especialistas em cirurgia de coluna, juntamente com opções de tratamento, para assim, obter um padrão de prescrição para o tratamento de espondilolistese degenerativa lombar. Estudo descritivo transversal observacional analítico. Resultados: Verificou-se que o tratamento de escolha para os casos de espondilolistese lombar degenerativa com sintomas axiais são conservadores. O tratamento cirúrgico de escolha para casos estáveis ou instáveis com radiculopatia e/ou claudicação é descompressão + enxerto posterolateral + instrumentação transpedicular + discectomia (enxerto). Conclusões: Foi possível definir as diretrizes de tratamento de espondilolistese lombar degenerativa em nossa unidade, que pode servir de base para o desenvolvimento de um guia de prática clínica.

RESUMEN Objetivos: Conocer el patrón de tratamiento de la espondilolistesis lumbar degenerativa en sus diferentes presentaciones clínicas en la UMAE Dr. Victorio de la Fuente Narváez. Métodos: Se presentaron a 36 médicos expertos en cirugía de columna 6 casos basados en la literatura, junto con las posibilidades de tratamiento, para obtener de este modo un patrón de prescripción para el tratamiento de espondilolistesis lumbar degenerativa. Estudio observacional descriptivo transversal analítico. Resultados: Se encontró que el tratamiento de elección para los casos de espondilolistesis lumbar degenerativa con sintomatología axial es conservador. El tratamiento quirúrgico de elección para los casos estables o inestables con radiculopatía y/o claudicación es la descompresión + injerto posterolateral + instrumentación transpedicular + discectomía (injerto). Conclusiones: Se logró definir la guía de tratamiento de espondilolistesis lumbar degenerativa en nuestra unidad, lo que puede servir como fundamento en la elaboración de una guía de práctica clínica.

Espondilolistese , Doenças da Coluna Vertebral , Terapêutica , Região Lombossacral
PeerJ ; 4: e2087, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27280077


This study examined direct associations between emotional competence, perceived stress and burnout in 489 Spanish teachers. In addition, a model in which perceived stress mediated pathways linking emotional competence to teacher burnout symptoms was also examined. Results showed that emotional competence and stress were significantly correlated with teacher burnout symptoms in the expected direction. Moreover, mediational analysis indicated that perceived stress partly mediated the relationship between emotional competence and the three dimensions of burnout even when controlling for salient background characteristics. These findings suggest an underlying process by which high emotional competence may increase the capacity to cope with symptoms of burnout, by reducing the experience of stress. Implications of these findings for future research and for working with teachers to prevent burnout are discussed.

J Environ Manage ; 177: 93-100, 2016 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-27085152


A laccase from the basidiomycete Pycnoporus sanguineus strain RVAN5 was evaluated for its ability to decolorize synthetic dyes and denim bleaching. Dye color reduction and denim bleaching were monitored at different dye concentrations and incubation times. Dye decolorization by Pycnoporus sanguineus fungal crude extract (FCE) ranged from 80 to 96% within 2-4 h at 25-65 °C. Comparable results were obtained when violuric acid (VA) was added as mediator to the FCE, however, the number of decolorized dyes increased significantly. Dye decolorization rates with VA varied of initial and final optical density (595 nm) values of 2.5-3.0 and 0.2-0.02, respectively. P. sanguineus FCE had no substantial effect on denim bleaching when used alone, notwithstanding, the mixture of FCE with VA (10 mM) showed significant denim color reduction values and considerably higher than those obtained with a bleaching enzyme from a commercial formulation; CIElab values obtained with FCE/VA mixture were of ΔL = 6.4, versus a ΔL 1.4 value obtained with an enzyme from commercial formulation.

Lacase/química , Lacase/metabolismo , Pycnoporus/enzimologia , Têxteis , Barbitúricos/química , Cor , Corantes/química , Proteínas Fúngicas/química , Proteínas Fúngicas/metabolismo , Pycnoporus/química
Iatreia ; 27(4): 375-385, oct.-dic. 2014. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-726835


Objetivo: evaluar la frecuencia de manifestaciones tempranas del síndrome de sobreentrenamiento (SSE) en deportistas antioqueños en el período precompetitivo antes de los Juegos Nacionales, Colombia 2012. Materiales y métodos: con el cuestionario de la Sociedad Francesa de Medicina del Deporte (SMFS) se hizo un estudio transversal de 153 deportistas de alto rendimiento pertenecientes a 28 disciplinas diferentes. Resultados: el promedio de edad fue de 23,6 ± 5,5 años; 56,9% eran hombres. La frecuencia de los síntomas tempranos del SSE fue 24,8%. En los afectados se halló mayor volumen de entrenamiento (24,3 ± 10,3 frente a 19,7 ± 9,4 horas/semana; p = 0,018); con mayor frecuencia pertenecían a una disciplina individual (81,6% frente a 55,7%; p = 0,017); estaban estudiando (76,3% frente a 56,5%; p = 0,030); se encontraban en períodos de exámenes (42,1 frente a 21,2%; p = 0,029) y habían percibido más situaciones de estrés en el último mes (62,2% frente a 16,2%; p < 0,01). Conclusiones: se encontró una alta frecuencia de manifestaciones tempranas del SSE, que fue mayor en las mujeres que en los hombres. Diversos factores individuales, relacionados con el entrenamiento y el tipo de deporte, podrían estar asociados con dichas manifestaciones.

Objective: To determine the frequency of early clinical symptoms of the overtraining syndrome (OTS), in athletes from Antioquia in the pre-competitive period prior to the National Sports Games, Colombia 2012. Materials and methods: The Sports Medicine French Society (SMFS) questionnaire was administered to 153 highly trained athletes, belonging to 28 sports disciplines. Results: Mean age of the studied athletes was 23.5 ± 5.5 years; 56.9% were men. Frequency of OTS early symptoms was 24.8%. The affected athletes had a greater volume of sport training (24.3 ± 10.3 vs. 19.7 ± 9.4 hours/week; p = 0.018); more commonly belonged to an individual sports discipline (81.6% vs. 55.7%; p = 0.017); more often they were studying (76.3% vs. 56.5%; p = 0.030) or in exams period (42.1 vs. 21.2%; p = 0.029) and perceived more stressful situations in the last month (62.1% vs. 16.2%; p < 0.01). Conclusions: a high frequency of early manifestations of OTS was found. It was higher in women than in men. Several individual factors, related to training and the type of sport, might be associated with these manifestations.

Objetivo: avaliar a frequência de manifestações precoces da síndrome de sobre-treinamento (SSE) em atletas antioqueños no período pré-competitivo antes dos Jogos Nacionais, Colômbia 2012. Materiais e métodos: com o questionário da Sociedade Francesa de Medicina do Esporte (SMFS) fez-se um estudo transversal de 153 atletas de alto rendimento pertencentes a 28 disciplinas diferentes. Resultados: a média de idade foi de 23,6 ± 5,5 anos; 56,9% eram homens. A frequência dos sintomas precoces do SSE foi de 24,8%. Nos afetados, se achou maior volume de treinamento (24,3 ± 10,3 frente a 19,7 ± 9,4 horas/semana; p = 0,018), com maior frequência pertenciam a uma disciplina individual (81,6% frente a 55,7%; p = 0,017), estavam estudando (76,3% frente a 56,5%; p = 0,030), encontravam-se em períodos de exames (42,1 frente a 21,2%; p = 0,029) e tinham percebido mais situações de estresse no último mês (62,2% frente a 16,2%; p < 0,01). Conclusões: encontrou-se uma alta frequência de manifestações precoces de SSE, que foi maior nas mulheres do que nos homens. Diversos fatores individuais, relacionados com o treinamento e o tipo de esporte, poderiam estar associados com ditas manifestações.

Humanos , Adulto Jovem , Atletas , Desempenho Atlético , Esportes
Int J Psychiatry Clin Pract ; 17(1): 2-9, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22731397


OBJECTIVE: To assess risk factors for relapse in patients with schizophrenia attended in daily practice. METHODS: Patients with schizophrenia admitted consecutively to short-stay/acute-care psychiatric units over a 6-month period were eligible. Variables statistically significant in the univariate logistic regression analysis were then subjected to multivariate analysis. RESULTS: The study population included 1646 patients (67.6% men). In the univariate analysis, low family support, duration of illness > 5 years, number of previous hospitalizations, cocaine and cannabis consumption, and number of different antipsychotic drug classes were risk factors for relapse. In the multivariate analysis, number of previous hospitalizations (odds ratio [OR] 1.29, 95% confidence interval [CI] 1.21-1.36) and number of different antipsychotics previously used (OR = 1.13, 95% CI 1.03-1.24) were significant predictors of relapse. The absence of cannabis consumption was a protective factor (OR = 0.72, 95% CI 0.58-0.89). Neither adherence to treatment in the previous 3 years nor type of antipsychotic regimen was significantly associated with relapse. CONCLUSIONS: Number of previous hospitalizations and number of different types of antipsychotic drugs were associated with relapse. Absence of cannabis consumption was a protective factor.

Esquizofrenia/epidemiologia , Adolescente , Adulto , Idoso , Antipsicóticos/uso terapêutico , Transtornos Relacionados ao Uso de Cocaína/epidemiologia , Estudos Transversais , Feminino , Seguimentos , Hospitalização/estatística & dados numéricos , Humanos , Masculino , Abuso de Maconha/epidemiologia , Pessoa de Meia-Idade , Estudos Prospectivos , Recidiva , Estudos Retrospectivos , Fatores de Risco , Esquizofrenia/tratamento farmacológico , Apoio Social , Espanha/epidemiologia , Fatores de Tempo , Adulto Jovem