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2.
Nanoscale ; 10(28): 13607-13616, 2018 Jul 19.
Artigo em Inglês | MEDLINE | ID: mdl-29978869

RESUMO

Nanogaps supporting cavity plasmonic modes with unprecedented small mode volume are attractive platforms for tailoring the properties of light-matter interactions at the nanoscale and revealing new physics. Hitherto, there is a concerning lack of analytical solutions to divide the complex interactions into their different underlying mechanisms to gain a better understanding that can foster enhanced designs. Bowtie apertures are viewed as an effective and appealing nanocavity and are studied here within the analytical frame of conformal transformation. We show how the non-radiative Purcell enhancement of a quantum emitter within the bowtie nanocavity depends strongly not only on the geometry of the nanocavity, but also on the position and orientation of the emitter. For a 20 nm diameter (∅ 20 nm) bowtie nanocavity, we report a change of up to two orders of magnitude in the maximum non-radiative Purcell enhancement and a shift in its peak wavelength from green to infra-red. The changes are tracked down to the overlap between the emitter field and the gap plasmon mode field distribution. This analysis also enables us to understand the self-induced trapping potential of a colloidal quantum dot inside the nanocavity. Since transformations can be cascaded, the technique introduced in this work can also be applied to a wide range of nanocavities found in the literature.

3.
Rev Chil Pediatr ; 88(3): 354-359, 2017 Jun.
Artigo em Espanhol | MEDLINE | ID: mdl-28737194

RESUMO

Noninvasive ventilation (NIV) frequently involves the development of facial pressure ulcers (FPU). Its prevention considers the empirical use of protective patches between skin and mask, in order to reduce the pressure exerted by it. OBJECTIVES: To evaluate the effect of protective patches on the pressure exerted by the facial mask, and its impact on the programmed ventilatory parameters. METHOD: Bilevel NIV simulated model using full face mask in phantom with a physiological airway (ALS PRO +) in supine position. Forehead, chin and cheekbones pressure were measured using 3 types of standard protective patches versus a control group using pressure sensors (Interlinks Electronics®). The values obtained with the protective patches-mask model were evaluated in the programmed variables maximum inspiratory flow (MIF)), expired tidal volume (Vte) and positive inspiratory pressure (IPAP), with Trilogy 100 ventilator, Respironics®. The programming and recording of the variables was carried out in 8 opportunities in each group by independent operators. RESULTS: There was no decrease in facial pressure with any of the protective patches compared to the control group. Moltopren increased facial pressure at all support points (p < 0.001), increased leakage, it decreased MIF, Vte and IPAP (p < 0.001). Hydrocolloid patches increased facial pressure only in the left cheekbone, increased leakage and decreased MIF. Polyurethane patches did not produce changes in facial pressure or ventilatory variables. CONCLUSION: The use of protective patches of moltopren, hydrocolloid and polyurethane transparent did not contribute to the decrease of the facial pressure. A deleterious effect of the moltopren and hydrocolloid patches was observed on the administration of ventilatory variables, concluding that the non-use of the protective patches allowed a better administration of the programmed parameters.


Assuntos
Bandagens , Pressão Positiva Contínua nas Vias Aéreas/instrumentação , Máscaras/efeitos adversos , Ventilação não Invasiva/instrumentação , Lesão por Pressão/prevenção & controle , Pressão/efeitos adversos , Face , Humanos , Manequins , Lesão por Pressão/etiologia
4.
Rev. chil. pediatr ; 88(3): 354-359, jun. 2017. ilus, tab
Artigo em Espanhol | LILACS-Express | ID: biblio-899987

RESUMO

La ventilación mecánica no invasiva (VMNI) tiene como complicación frecuente el desarrollo de úlceras faciales por presión (UPP). Su prevención considera el uso empírico de parches protectores entre piel y mascarilla, para disminuir la presión ejercida por ésta. Objetivos: Evaluar el efecto de los parches protectores sobre la presión ejercida por la mascarilla facial, y su impacto en los parámetros ventilatorios programados. Método: Modelo simulado de VMNI binivelada usando mascarilla facial total en fantoma con vía aérea fisiológica (ALS PRO+) en posición supina. Se midió la presión en frente, mentón y pómulos, usando 3 tipos de parches protectores de uso habitual versus un grupo control, utilizando sensores de presión (Interlinks Electronics®). Se evaluaron los valores obtenidos con el modelo de mascarilla-parches protectores en las variables programadas flujo máximo inspiratorio (FMI), volumen corriente espirado (Vte) y presión positiva inspiratoria (IPAP), con ventilador Trilogy 100, Respironics®. La programación y registro de las variables fue efectuada en 8 oportunidades en cada grupo por operadores independientes. Resultados: No se observó disminución de la presión facial con ninguno de los parches protectores respecto al grupo control. Moltoprén aumentó la presión facial en todos los puntos de apoyo (p < 0,001), aumentó fuga, disminuyó FMI, Vte e IPAP (p < 0,001). Parches de hidrocoloide aumentaron la presión facial sólo en pómulo izquierdo, aumentaron la fuga y disminuyeron FMI. Parches de poliuretano no generaron cambios en la presión facial ni en variables ventilatorias. Conclusión: El uso de parches protectores de moltoprén, hidrocoloide y poliuretano transparente no contribuyó a la disminución de la presión facial. Se observó un efecto deletéreo de los parches de moltoprén e hidrocoloide sobre la administración de variables ventilatorias, concluyendo que el no uso de los parches protectores permitió una mejor administración de los parámetros programados.


Noninvasive ventilation (NIV) frequently involves the development of facial pressure ulcers (FPU). Its prevention considers the empirical use of protective patches between skin and mask, in order to reduce the pressure exerted by it. Objectives: To evaluate the effect of protective patches on the pressure exerted by the facial mask, and its impact on the programmed ventilatory parameters. Method: Bilevel NIV simulated model using full face mask in phantom with a physiological airway (ALS PRO +) in supine position. Forehead, chin and cheekbones pressure were measured using 3 types of standard protective patches versus a control group using pressure sensors (Interlinks Electronics®). The values obtained with the protective patches-mask model were evaluated in the programmed variables maximum inspiratory flow (MIF)), expired tidal volume (Vte) and positive inspiratory pressure (IPAP), with Trilogy 100 ventilator, Respironics®. The programming and recording of the variables was carried out in 8 opportunities in each group by independent operators. Results: There was no decrease in facial pressure with any of the protective patches compared to the control group. Moltopren increased facial pressure at all support points (p < 0.001), increased leakage, it decreased MIF, Vte and IPAP (p < 0.001). Hydrocolloid patches increased facial pressure only in the left cheekbone, increased leakage and decreased MIF. Polyurethane patches did not produce changes in facial pressure or ventilatory variables. Conclusion: The use of protective patches of moltopren, hydrocolloid and polyurethane transparent did not contribute to the decrease of the facial pressure. A deleterious effect of the moltopren and hydrocolloid patches was observed on the administration of ventilatory variables, concluding that the non-use of the protective patches allowed a better administration of the programmed parameters.

5.
Sci Rep ; 6: 19642, 2016 Jan 21.
Artigo em Inglês | MEDLINE | ID: mdl-26791421

RESUMO

Coralline red algae are significant components of sea bottom and up to now considered as exclusively marine species. Here we present the first coralline alga from a freshwater environment, found in the Cetina River (Adriatic Sea watershed). The alga is fully adapted to freshwater, as attested by reproductive structures, sporelings, and an inability to survive brackish conditions. Morphological and molecular phylogenetic analyses reveal the species belongs to Pneophyllum and is described as P. cetinaensis sp. nov. The marine-freshwater transition most probably occurred during the last glaciation. The brackish-water ancestor was preadapted to osmotic stress and rapid changes in water salinity and temperature. The particular characteristics of the karst Cetina River, such as hard water enriched with dissolved calcium carbonate and a pH similar to the marine environment, favoured colonization of the river by a marine species. The upstream advance and dispersal is facilitated by exceptionally pronounced zoochory by freshwater gastropods. Pneophyllum cetinaensis defies the paradigm of Corallinales as an exclusively marine group.


Assuntos
Ecossistema , Água Doce , Rodófitas , Genes Bacterianos , Filogenia , Rodófitas/classificação , Rodófitas/genética , Rodófitas/ultraestrutura , Esporos Bacterianos
6.
Br Dent J ; 220(1): 11-4, 2016 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-26768458

RESUMO

The sectional matrix is the best way to achieve a strong contact point in Class II restorations with composite resin in the posterior dental sector. The pre-wedging is essential to get a separation between teeth which avoid the matrix deformation during its insertion. This article describes the clinical technique for restoring Class II cavities using a sectional matrix.


Assuntos
Materiais Dentários/uso terapêutico , Restauração Dentária Permanente/métodos , Cárie Dentária/cirurgia , Preparo da Cavidade Dentária/métodos , Humanos
7.
Rev. chil. endocrinol. diabetes ; 8(4): 151-153, oct. 2015.
Artigo em Espanhol | LILACS | ID: biblio-831328

RESUMO

Diabetes mellitus secondary to pancreatic diseases is classified as type 3C and it can appear after a single episode of acute pancreatitis. We report a 25 years old female with a family history of diabetes. She was admitted to the hospital due to an acute pancreatitis of biliary origin. She received parenteral nutrition and required up to 82 units of insulin per day to maintain blood glucose levels. A CT scan showed a pseudocyst. A percutaneous drainage, followed by necrotic tissue debridement were performed. She was discharged two months after admission requiring insulin to maintain metabolic control.


Assuntos
Humanos , Adulto , Feminino , Diabetes Mellitus/etiologia , Pancreatite/complicações , Pancreatite/terapia , Doença Aguda
8.
Opt Lett ; 40(10): 2329-32, 2015 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-26393731

RESUMO

A photonic jet (a terajet at terahertz frequencies) commonly denotes a specific, spatially localized region in the near field on the front side of a dielectric particle with a diameter comparable with the wavelength illuminated by a plane wave on its back side (i.e., the jet emerges from the shadow surface of a dielectric particle). In this Letter, the formation of a photonic jet is demonstrated using the recently proposed three-dimensional (3D) dielectric cuboids working in the "reflection" mode when the specific, spatially localized region is localized in the direction of the incident wavefront. The results of the simulations based on the Finite Integration Technique are discussed. All dimensions are given in wavelength units so that all results can be scaled to any frequency of interest, including optical frequencies, thus simplifying the fabrication process compared with spherical dielectrics. The results presented here may be of interest for novel applications, including microscopy techniques and sensors.

9.
Oper Dent ; 40(5): 458-61, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26151458

RESUMO

This article describes the use of a copper band as a matrix to build up resin cores in endodontically treated teeth that have a partially subgingival margin. The copper band is adjusted to the contour of the remaining dental structure and extends beyond the margins to ensure complete isolation in order to provide a matrix to fabricate a core.


Assuntos
Resinas Compostas , Cobre , Fraturas dos Dentes , Dente não Vital , Planejamento de Prótese Dentária , Humanos , Técnica para Retentor Intrarradicular , Raiz Dentária
10.
Opt Express ; 23(7): 8555-64, 2015 Apr 06.
Artigo em Inglês | MEDLINE | ID: mdl-25968693

RESUMO

Metamaterial lenses with close values of permittivity and permeability usually display low reflection losses at the expense of narrow single frequency operation. Here, a broadband low-profile lens is designed by exploiting the dispersion of a fishnet metamaterial together with the zoning technique. The lens operates in a broadband regime from 54 GHz to 58 GHz, representing a fractional bandwidth ~7%, and outperforms Silicon lenses between 54 and 55.5 GHz. This broadband operation is demonstrated by a systematic analysis comprising Huygens-Fresnel analytical method, full-wave numerical simulations and experimental measurements at millimeter waves. For demonstrative purposes, a detailed study of the lens operation at two frequencies is done for the most important lens parameters (focal length, depth of focus, resolution, radiation diagram). Experimental results demonstrate diffraction-limited ~0.5λ transverse resolution, in agreement with analytical and numerical calculations. In a lens antenna configuration, a directivity as high as 16.6 dBi is achieved. The different focal lengths implemented into a single lens could be potentially used for realizing the front end of a non-mechanical zoom millimeter-wave imaging system.

11.
Opt Lett ; 40(2): 245-8, 2015 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-25679855

RESUMO

In the past, it has been demonstrated that it is possible to produce terajets with high resolution at its focus using 3D dielectric cuboids under plane-wave illumination. Here, a systematic study of the harmonic and angular response of terajets using cuboids is performed. Mutifrequency focusing is demonstrated at the fundamental frequency and two higher frequency harmonics showing an intensity enhancement of ∼10, ∼18, and ∼14 for each case. This capability to use 3D dielectric cuboids to produce terajets at the fundamental frequency and first harmonic is experimentally evaluated at sub-THz frequencies, with good agreement with numerical results. Moreover, a robust angular response is demonstrated numerically and experimentally showing that the intensity at the focal position is maintained in a wide angular range (from 0° to 45°), demonstrating the capability to work as a wide scanning terajet-focusing lens. The results here presented may be scaled at different frequency bands such as optical frequencies and may be used in microscopy techniques and sensors.

12.
Biochem Biophys Res Commun ; 451(4): 609-14, 2014 Sep 05.
Artigo em Inglês | MEDLINE | ID: mdl-25128831

RESUMO

In this work we characterized the infection of a primary culture of rat osteoblastic lineage cells (OBCs) with measles virus (MeV) and the effect of infection on cell differentiation and maturation. Infection of OBCs with MeV led to high titers of infectivity released early after infection. Also, analysis of mRNAs corresponding to osteogenic differentiation markers like alkaline phosphatase (ALP), bone sialo-protein (BSP) and bone morphogenetic proteins (BMPs) 1-4-5-7 in OBCs revealed higher values (2-75-fold of increment) for infected cells in comparison with uninfected controls. Differentiation of OBCs in osteogenic medium prior to infection influenced the level of stimulation induced by MeV. Furthermore, treatment of OBCs with Ly294002, a PI3K/AKT inhibitor, increased viral titers, whereas treatment with 10µM or 100µM ATPγS diminished MeV multiplication. In addition, increments of osteogenic differentiation markers induced by MeV infection were not modified either by treatment with Ly294002 or ATPγS. These data provide the first evidence demonstrating that MeV can infect osteoblasts in vitro leading to osteoblastic differentiation, a key feature in bone pathogenic processes like otosclerosis.


Assuntos
Vírus do Sarampo/fisiologia , Osteoblastos/virologia , Osteogênese/fisiologia , Trifosfato de Adenosina/análogos & derivados , Trifosfato de Adenosina/farmacologia , Fosfatase Alcalina/biossíntese , Animais , Proteína Morfogenética Óssea 4/biossíntese , Osso e Ossos/metabolismo , Diferenciação Celular/efeitos dos fármacos , Células Cultivadas , Cromonas/farmacologia , Morfolinas/farmacologia , Osteoblastos/fisiologia , Otosclerose/etiologia , Ratos , Replicação Viral
13.
Oper Dent ; 39(2): 136-43, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-23862715

RESUMO

OBJECTIVE: This randomized clinical trial evaluated the efficacy and safety of four gels of differing concentrations used for at-home vital bleaching. MATERIALS AND METHODS: Ninety-six volunteers participated in the study and were divided into four groups of 24 individuals. A gel of differing concentration was used for each group: 10% and 15% carbamide peroxide and 7.5% and 9.5% hydrogen peroxide. The patients used the whitening agent in a tray without reservoirs for one hour per day for two weeks. The measurement of the change in tooth color was made by two observers in the maxillary right central incisor and with a colorimeter in both upper central incisors and canines, using the CIE L*a*b* and CIE L*C*h* values. Sensitivity was evaluated by the participants on a scale with values as follows: 0 = absent, 1 = minor, 2 = moderate, 3 = considerable, 4 = severe. RESULTS: At the baseline, the observers noted darker colors than the colorimeter (p<0.01), and there were differences between incisors and canines in all the CIE L*a*b* and CIE L*C*h* values (p<0.001). In all of the groups and for all of the CIE L*a*b* and CIE L*C*h* parameters, there were color changes in the assessments made in the four maxillary teeth after treatment (p<0.001). There were no differences in ΔL* and ΔE* between the groups. The number of patients who experienced sensitivity and the intensity of the sensitivity were not significant. CONCLUSIONS: There were no differences in the degree of whitening among the different products. With all of the products there was an increase in L*, a decrease in chromatic intensity (C*), and an increase in the value (tone) or hue (h*).


Assuntos
Clareadores Dentários/uso terapêutico , Clareamento Dental/métodos , Adulto , Peróxido de Carbamida , Sensibilidade da Dentina/induzido quimicamente , Feminino , Géis , Humanos , Peróxido de Hidrogênio/efeitos adversos , Peróxido de Hidrogênio/uso terapêutico , Masculino , Peróxidos/efeitos adversos , Peróxidos/uso terapêutico , Autocuidado/efeitos adversos , Autocuidado/métodos , Clareamento Dental/efeitos adversos , Clareadores Dentários/efeitos adversos , Resultado do Tratamento , Ureia/efeitos adversos , Ureia/análogos & derivados , Ureia/uso terapêutico
14.
Cir. plást. ibero-latinoam ; 39(4): 419-422, oct.-dic. 2013. ilus
Artigo em Espanhol | IBECS | ID: ibc-121520

RESUMO

Las quemaduras son una de las causas más importantes de discapacidad y mortalidad en todo el mundo. En las producidas por electricidad de alto voltaje, las manifestaciones sistémicas más frecuentes son la insuficiencia renal y las arritmias. La lesión visceral secundaria a una quemadura eléctrica es infrecuente y su tratamiento quirúrgico constituye un desafío. En este artículo presentamos el caso clínico de un paciente con quemadura eléctrica de alto voltaje con compromiso de la pared abdominal y lesión intestinal secundaria (AU)


Burns are one of the leading causes of disability and mortality worldwide. In high-voltage electrical burns most common systemic manifestations are renal failure and arrhythmias. Visceral injury secondary to electrical burn is rare and its surgical management is challenging. This article presents a case of a patient with highvoltage electrical burn with involvement of the abdominal wall and secondary bowel injury (AU)


Assuntos
Humanos , Masculino , Adulto , Queimaduras por Corrente Elétrica/cirurgia , Intestinos/lesões , Traumatismos Abdominais/complicações , Laparotomia
15.
Acta Ortop Mex ; 27(4): 236-9, 2013.
Artigo em Espanhol | MEDLINE | ID: mdl-24707612

RESUMO

OBJECTIVE: To show that patients with intertrochanteric fractures treated with a proximal femoral nail have a better postoperative course than those treated with a DHS plate (dynamic hip screw). METHODS: Patients with a Boyd & Griffin type II intertrochanteric fracture were randomly divided into two groups: a group of patients treated with a PFN and another one treated with a DHS plate. All patients were assessed at 2, 4, 8 and 16 weeks using the Harris scale and the visual analog scale pre- and postoperatively, as well as the operative time, incision size, intraoperative bleeding, onset of partial and/or total weight bearing, healing time, time to attain prior physical activity level, and radiographic result. RESULTS: 32 patients met our criteria. The variables that had a significant reduction were: incision, operative time, postoperative pain according to the visual analog scale, onset of mobility, partial weight bearing and pain at 2 weeks. CONCLUSIONS: The proximal femoral nail has better short-term outcomes than the DHS plate; however, in the medium term both implants have the same outcomes.


Assuntos
Pinos Ortopédicos , Placas Ósseas , Fixação Intramedular de Fraturas/instrumentação , Fraturas do Quadril/cirurgia , Idoso , Idoso de 80 Anos ou mais , Desenho de Equipamento , Feminino , Humanos , Estudos Longitudinais , Masculino , Estudos Prospectivos
16.
Burns ; 39(1): 126-9, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22464750

RESUMO

INTRODUCTION: Amputation is a rare procedure among burned patients. However, it has significant physical and psychological consequences which impact quality of life. OBJECTIVE: To study the incidence, etiology and prognostic factors associated with amputation among burned patients in Chile. METHODS: Cohort study of patients admitted to the Reference Burn Center of Chile from 2006 to 2011. Association of demographic, event and injury variables with the likelihood of amputation were evaluated by using multivariable analysis. RESULTS: Amputation incidence was 5.8% in 1090 admitted patients. Male amputee patients were significantly more frequent (p=0.01), with more electrical and high voltage burns (p<0.01) and had greater frequency of impaired consciousness (p=0.03). Multivariable analysis identified electrical burns (OR 13.7; 95% CI 6.7-28.1) and impaired consciousness (OR 2.8; 95% CI 1.4-5.7) as prognostic factors for amputation. CONCLUSION: Amputation is a low incidence procedure among burned patients. Patients who underwent amputations are frequently at working age. Patients with high-voltage electrical burns and impaired consciousness are more likely to undergo amputation. Since these are highly incapacitating injuries, it is very important to implement preventive measures.


Assuntos
Amputação/estatística & dados numéricos , Queimaduras/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Chile , Estudos de Coortes , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Prognóstico , Estudos Retrospectivos , Fatores de Risco , Adulto Jovem
17.
Chem Biodivers ; 9(8): 1599-610, 2012 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-22899620

RESUMO

The aim of this study was to quantify mucilages, pectins, hemicelluloses, and cellulose of nopalitos (edible, as vegetable, young cladodes of flat-stemmed spiny cacti) of most consumed Mexican cultivars, and sweet and acid cactus pear fruits of Opuntia spp. The hypothesis is that, regardless of their unavailable polysaccharides diversity, nopalitos and cactus pear fruits are rich sources of soluble and insoluble dietary fiber. Twelve cultivars of Opuntia spp. were used. Nopalitos had a significant variation in structural polysaccharides among the cultivars: mucilages (from 3.8 to 8.6% dry matter (DM)) averaged near a half of pectins content (from 6.1 to 14.2% DM) and tightly bound hemicelluloses (from 2.2 to 4.7% DM), which were the less abundant polysaccharides, amounted 50% of the loosely bound hemicelluloses (from 4.3 to 10.7% DM). Acid fruits (or 'xoconostle') had significantly higher unavailable polysaccharides content than sweet fruit, and contain similar proportions than nopalitos. Unavailable polysaccharides represent a high proportion of dry tissues of nopalitos and cactus pear fruits, composition of both of these soluble and insoluble polysaccharides (total dietary fiber) widely vary among cultivars without an evident pattern. Nopalitos and cactus pear fruit can be considered an excellent source of dietary fiber.


Assuntos
Fibras na Dieta/análise , Frutas/química , Opuntia/química , Polissacarídeos/análise , Celulose/análise , Pectinas/análise , Mucilagem Vegetal/análise
18.
Rev. Univ. Ind. Santander, Salud ; 43(3): 271-279, oct.-dic. 2011. ilus, tab
Artigo em Espanhol | LILACS-Express | ID: lil-657134

RESUMO

Introducción: Es posible evitar muertes neonatales mediante la lactancia materna desde el primer día de vida, pues la leche materna es el alimento óptimo para el lactante por su contenido nutricional necesario favorecer el crecimiento y desarrollo. Objetivo: Determinar la prevalencia y factores asociados al diagnóstico de enfermería "Lactancia materna ineficaz" en lactantes menores de 6 meses hospitalizados en una institución de tercer nivel. Metodología: Estudio de corte transversal. Se seleccionaron 108 binomios (madre e hijo) hospitalizados en una institución de tercer nivel de atención en el año 2009, se aplicó un formato validado para identificar el diagnóstico. Se realizó análisis Rasch a las variables que representan las características definitorias del diagnóstico, con el cual se creó una escala de 0 a 100 y se construyó un modelo de regresión lineal con las variables asociadas a la medida del diagnóstico. Resultados: la prevalencia del diagnóstico fue de 93,5 %, la característica definitoria más fácil de encontrar fue Incapacidad del lactante para agarrarse al pecho materno y la más difícil fue agitación y llanto del lactante dentro de la primera hora después de la lactancia materna. La regresión lineal mostró factores asociados como: género femenino, peso del lactante y necesidad de la madre de ir a orinar. Conclusión: Existe una tendencia desfavorable tanto en la prevalencia como en la duración de la lactancia materna para los lactantes hospitalizados; la promoción de la lactancia materna debe ser un trabajo interdisciplinario; modificar las normas hospitalarias favoreciendo el contacto del binomio y la puesta temprana al pecho materno. Salud UIS 2011; 43 (3): 271-279.


Introduction: neonatal deaths can be prevented by breastfeeding from the first day of life, as is the optimal food for infants by their nutritional content required for better growth and development. Objective: To determine the prevalence and associated factors with nursing diagnosis "ineffective breastfeeding" in infants under than 6 months hospitalized in a tertiary institution. Methodology: Cross sectional study. We selected 108 pairs (mother and child) hospitalized in an institution of tertiary care in 2009, we applied a validated format to identify the diagnosis. Rasch analysis was performed for variables that represent the defining characteristics of the diagnosis, which created a scale of 0 to 100 and built a linear regression model the variables associated with the extent of diagnosis. Results: Prevalence of diagnosis was 93,5 %, the defining characteristic was easier to find the infant’s inability to hold on to the breast and the hardest was shaking and crying of the infant within the first hour after breastfeeding. Linear regression was associated factors such as: female gender, weight infant and the mother need to urinate. Conclusion: There is an unfavorable trend in both the prevalence and duration of breastfeeding for infants hospitalized, promotion of breastfeeding should be an interdisciplinary, modify hospital policies favoring the contact of the binomial and the early start to the chest maternal. Salud UIS 2011; 43 (3): 271-279.

19.
Proc West Pharmacol Soc ; 54: 78-9, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-22423587

RESUMO

Ganoderma lucidum, a traditional Chinese medicine, has been shown to target the Central Nervous System. In this work we analyze whether G. lucidum, collected in Mexico, has a protective effect in the hippocampus of rats treated with kainic acid, a neurotoxin that causes seizures and neuronal loss. The aqueous extract of G. lucidum (10 mg/Kg, i.p.) was administered to rats 30 min before kainic acid injection (5 mg/Kg, i.p.). Animals that had received prior treatment with G. lucidum showed no tonic-clonic seizure activity. Histopathological analysis showed a significant decrease in neuronal loss and cellular alterations in the hippocampal CA3 region. Immunohistochemical analysis shows that when using G. lucidum in rats, there is less immunoreactivity for GFAP as well as TNF-alpha and IL-1beta in the CA3 region when compared with rats treated with kainic acid. Our results demonstrate that G. lucidum protects against kainic acid-induced alterations of hippocampal cells and expression of immunological markers in this model of excitotoxicity.


Assuntos
Proteína Glial Fibrilar Ácida/análise , Hipocampo/efeitos dos fármacos , Interleucina-1beta/análise , Ácido Caínico/toxicidade , Reishi , Animais , Hipocampo/química , Masculino , Ratos , Ratos Wistar
20.
Clin Endocrinol (Oxf) ; 72(4): 489-95, 2010 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-19863573

RESUMO

OBJECTIVE: To assess normative data and the usefulness of spontaneous and LHRH analogue-stimulated serum LH and FSH levels measured by immunoradiometric assays (IRMA) in the evaluation of normal puberty. DESIGN: Prospective. Healthy girls in Tanner I and Tanner II from the local community were invited to participate (n = 47). METHODS: A leuprolide acetate test (500 mcg/m(2); sc) was performed. LH and FSH levels were determined using IRMA. Tanner II girls were assessed every 6 months until Tanner V. Girls who progressed from Tanner II to Tanner III in the next 6 months were called Tanner II-2; otherwise, they were called Tanner II-1. RESULTS: The prepubertal upper limit (CI 95%) was 0.49 IU/l for basal LH and 5.1 IU/l for stimulated LH. Taking into account these LH cut-off limits, 72.2% and 66.7% of Tanner II-1 and 41.6% and 41.7% of Tanner II-2 subjects presented overlapping values for basal and stimulated LH, respectively, as compared with the Tanner I group. The cut-offs for basal and stimulated LH to predict progression from Tanner II to Tanner III in the next 6 months were a basal LH level > or =0.49 IU/l (Sensitivity = 0.58; 1-Specificity = 0.33) and a poststimulated LH level > or =4.75 IU/l (Sensitivity = 0.67; 1-Specificity = 0.44). CONCLUSION: According to an IRMA, the basal and leuprolide acetate gonadotrophin response patterns during the beginning stages of puberty overlapped between Tanner I and Tanner II, and the cut-offs of basal and stimulated LH levels to predict progress from Tanner II to Tanner III had low sensitivities for the following 6 months.


Assuntos
Hormônio Foliculoestimulante/sangue , Leuprolida , Hormônio Luteinizante/sangue , Puberdade/fisiologia , Área Sob a Curva , Criança , Pré-Escolar , Feminino , Humanos , Estudos Longitudinais , Sensibilidade e Especificidade
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