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1.
Psychol Health Med ; : 1-15, 2021 Jan 18.
Artigo em Inglês | MEDLINE | ID: mdl-33459044

RESUMO

Entering university brings on changes in lifestyle and psychological stress and has been associated with increased risk of 1988 in college students. This study aimed to investigate the incidence of depressive symptoms and associated sociodemographic and lifestyle factors among university students. A dynamic cohort of freshmen was followed up for three years, starting at their entry to university (baseline) and then annually. A structured auto administered questionnaire was applied to obtain information on age, sex, economic class, living situation, smoking and drinking, sedentary and sleep behaviors, and change in physical activity after university admission. Depressive symptoms were assessed using the Patient Health Questionaire-9. Incidence and incidence rate of depressive symptoms were calculated. Poisson Regression with robust variance was used to identify risk factors associated to these disorders. A total of 1,034 students without depressive symptoms at baseline were investigated. The overall incidence of depressive symptoms was 28.3% and the incidence rate (IR) was 2.12, being greater for females (2.75) than males (1.65). The IR decreased over time for both males (from 2.61 to 0.41) and females (from 4.25 to 0.54). A greater risk of depressive symptoms was observed for younger male students compared to those ≥20 years old (IRRadj = 1.64) and for women who reported concomitant use of alcohol and tobacco compared to those that reported no smoking and no alcohol consumption. For both males (IRRadj = 2.80) and females (IRRadj = 1.91), severe stress level was associated with greater risk of depressive symptoms when compared to mild stress level. Depressive Symptoms occurred more significantly in females, in the early years of undergraduate course, in males <20 years old, and among those with high stress level. Understanding the possible causes of depression is essential to promote mental health and well-being among college student.

2.
Soins Psychiatr ; 41(328): 23-25, 2020.
Artigo em Francês | MEDLINE | ID: mdl-33039087

RESUMO

Psychiatric compulsory community treatment programmes are widely and heterogeneously used measures of coercion. The recovery oriented mental health service 59G21 used them to minimize violating the rights of persons under compulsory care. Based on a clinical situation of failing this objective, we discuss their place in the health system and the reasons why we chose to move towards a "zero recourse" objective.


Assuntos
Serviços Comunitários de Saúde Mental , Transtornos Mentais/terapia , Humanos , Direitos do Paciente
3.
Biosci Rep ; 40(8)2020 08 28.
Artigo em Inglês | MEDLINE | ID: mdl-32785580

RESUMO

In recent years, the antimicrobial activity of peptides isolated from a wide variety of organs from plant species has been reported. However, a few studies have investigated the potential of antimicrobial peptides (AMPs) found in fruits, especially Capsicum chinense (pepper). The present study aimed to purify and characterize peptides from Capsicum chinense fruits and evaluate their inhibitory activities against different phytopathogenic fungi and also analyze the possible mechanisms of action involved in microbial inhibition. After fruit protein extraction and high-performance liquid chromatography (HPLC), different fractions were obtained, named F1 to F10. Peptides in the F4 and F5 fractions were sequenced and revealed similarity with the plant antimicrobial peptides like non-specific lipid transfer proteins and defensin-like peptide. The F4 and F5 fractions presented strong antimicrobial activity against the fungus Fusarium solani and Fusarium oxysporum, causing toxic effects on these fungi, leading to membrane permeabilization, endogenous reactive oxygen species increase, activation of metacaspase and loss of mitochondrial function.

4.
J Chem Inf Model ; 58(11): 2294-2304, 2018 11 26.
Artigo em Inglês | MEDLINE | ID: mdl-30388003

RESUMO

We previously characterized the inhibitory activity of human salivary α-amylase (HSA) and Callosobruchus maculatus intestinal α-amylases by the plant lipid transfer protein from Vigna unguiculata ( Vu-LTP). Herein, we further study this inhibitory activity. First by an analysis of protein α-amylase inhibitors complexed with α-amylase, we find that positively charged amino acids of inhibitors interact with the active site of α-amylases and we know that Vu-LTP is rich in positively charged amino acid residues. For this reason, we model Vu-LTP, and based on its three-dimensional structure, we choose five peptides to be synthesized. Herein, we report that two peptides of Vu-LTP are responsible for HSA inhibition. A comparison of primary and tertiary structures of LTPs with and without inhibitory activity against α-amylase, superimposed with the sequence of Vu-LTP mapped for HSA inhibition, reinforces our suggestion that positively charged amino acids in loops are responsible for the inhibition. To prove our observation, one modified peptide is synthesized in which Arg39 is replaced by Gln. This modified peptide loses the HSA inhibitory property presented by the unmodified peptide. Therefore, we describe a new biological active for Vu-LTP, i.e. the α-amylase inhibitory activity that is not a fortuitous biological activity and probably has evolved to perform a biological function which is still unknown. A good candidate should be defense against insects. The results of this study also expand the possible biotechnological applications of LTPs.


Assuntos
Antígenos de Plantas/metabolismo , Proteínas de Transporte/metabolismo , Proteínas de Plantas/metabolismo , Vigna/metabolismo , alfa-Amilases/metabolismo , Sequência de Aminoácidos , Antígenos de Plantas/química , Proteínas de Transporte/química , Humanos , Modelos Moleculares , Proteínas de Plantas/química , Conformação Proteica , Alinhamento de Sequência , Vigna/química , alfa-Amilases/química
5.
Int J Microbiol ; 2018: 8546470, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30123275

RESUMO

The objective of the present study was to evaluate the antimicrobial activity of the Cc-LTP2 and Cc-GRP peptides isolated from Coffea canephora seeds and their possible synergistic activity with the azole drug fluconazole and characterize their mechanisms of action on cells of pathogenic fungi. Cc-LTP2 and Cc-GRP alone or in combination with 20 µg/mL of fluconazole were evaluated for their antimicrobial activity on the fungus Fusarium solani, and the effects of these peptides on the permeability of membranes and the induction of oxidative stress were determined. Our results show that these peptides at a concentration of 400 µg/mL combined with 20 µg/mL of fluconazole were able to inhibit the growth of the tested fungi, promote changes in their growth pattern, permeabilize the membrane, and induce reactive oxygen species (ROS). Some of these results were also observed with the peptides alone or with fluconazole alone, suggesting that the peptides act synergistically, promoting the potentiation of antimicrobial action. In this study, it was shown that Cc-LTP2 and Cc-GRP in combination with fluconazole were able to inhibit the growth of the fungus F. solani, to promote permeabilization of its membrane, and to induce the production of ROS, suggesting a combinatorial activity between the peptides and fluconazole.

6.
Saúde Redes ; 4(3): 49-61, jul. - set. 2018.
Artigo em Português | LILACS-Express | LILACS | ID: biblio-1015153

RESUMO

Objetivo: Avaliar se profissionais de saúde da equipe de saúde da família reconhecem a notificação de eventos adversos a medicamentos (EAM) como forma de promoção a Segurança do Paciente e as possíveis barreiras para execução da mesma. Método: Aplicação de questionário semiestruturado em 24 unidades de saúde de atenção primária em saúde (APS). Resultados: Foram 175 respondentes: 53 agentes comunitários de saúde, 7 agentes de saúde bucal, 25 enfermeiros, 18 médicos, 14 odontólogos, 58 técnicos de enfermagem. A falta de confiança, medo de exposição por má prática e o medo de perda da reputação foram as barreiras a notificação para os respondentes que possuem menor tempo de trabalho na unidade de saúde. Os profissionais com maior tempo de trabalho na unidade atribuem o tempo como barreira a notificação de EAM. Conclusão: As barreiras identificadas sinalizam a necessidade de intervenções na cultura da segurança do paciente na APS.A equipe da estratégia de saúde da família pode ser um elo de aproximação da APS com os Núcleos de Segurança do Paciente na prevenção de EAM. (AU)


Objective: To evaluate whether health professionals in the family health team recognize the notification of adverse drug-related events as a way to promote patient safety and possible barriers to patient implementation. Method: Application of a semi- structured questionnaire in 24 health units of primary health care. Results: There were 175 respondents: 53 community health agents, 7 oral health agents, 25 nurses, 18 physicians, 14 dentists, 58 nursing technicians. Lack of trust, fear of malpractice exposure, and fear of loss of reputation were the barriers to reporting to respondents who have shorter working hours at the health facility. The professionals with greater time of work in the unit attribute the time as barrier to the notification of EAM. Conclusion: The identified barriers signal the need for interventions in the patient safety culture in primary health care. The family health strategy team may be a link between primary health care and Patient Safety Centers in the prevention of adverse drug-related events. (AU)

7.
Cad Saude Publica ; 34(4): e00145917, 2018 03 29.
Artigo em Inglês | MEDLINE | ID: mdl-29617489

RESUMO

Admission to a university may cause significant changes in the pattern of exposure to health risks. The aim of this paper is to describe the study design and methodological procedures adopted in the Longitudinal Study on the Lifestyle and Health of University Students (ELESEU). This study examines a dynamic cohort of full-time students at a public university in the State of Mato Grosso, Brazil. This research, which started in 2015, will have four years of follow-up and is scheduled to end in 2018. A self-administered questionnaire is applied, containing questions regarding demographic and socioeconomic characteristics, and information on health conditions and risk factors such as lifestyle, perceived stress, symptoms of depression, body image, risk behaviors for eating disorders, self-assessment of health and diet quality, and other issues related to nutrition and health. Anthropometric and blood pressure measurements are also recorded. Two 24-hour dietary recalls and cholesterol, triglycerides, and glucose capillary measurements are collected in 50% of the students. In 2015, 495 participants (82.6% of the eligible students) were assessed in the baseline study. Of these, 348 (70.3%) were followed up in 2016. In 2016, 566 participants were included in the cohort (81% of the eligible students). This study will help to identify the factors that might influence changes in the nutritional, health, and metabolic status of young adults during college life.


Assuntos
Estilo de Vida , Estudantes/estatística & dados numéricos , Universidades , Adolescente , Adulto , Brasil , Comportamento Alimentar , Feminino , Humanos , Estudos Longitudinais , Masculino , Síndrome Metabólica , Estado Nutricional , Fatores de Risco , Inquéritos e Questionários , Adulto Jovem
8.
Cad. Saúde Pública (Online) ; 34(4): e00145917, 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-889948

RESUMO

Admission to a university may cause significant changes in the pattern of exposure to health risks. The aim of this paper is to describe the study design and methodological procedures adopted in the Longitudinal Study on the Lifestyle and Health of University Students (ELESEU). This study examines a dynamic cohort of full-time students at a public university in the State of Mato Grosso, Brazil. This research, which started in 2015, will have four years of follow-up and is scheduled to end in 2018. A self-administered questionnaire is applied, containing questions regarding demographic and socioeconomic characteristics, and information on health conditions and risk factors such as lifestyle, perceived stress, symptoms of depression, body image, risk behaviors for eating disorders, self-assessment of health and diet quality, and other issues related to nutrition and health. Anthropometric and blood pressure measurements are also recorded. Two 24-hour dietary recalls and cholesterol, triglycerides, and glucose capillary measurements are collected in 50% of the students. In 2015, 495 participants (82.6% of the eligible students) were assessed in the baseline study. Of these, 348 (70.3%) were followed up in 2016. In 2016, 566 participants were included in the cohort (81% of the eligible students). This study will help to identify the factors that might influence changes in the nutritional, health, and metabolic status of young adults during college life.


O ingresso na universidade, para o aluno, pode provocar mudanças significativas no perfil de exposição a riscos para a saúde. O artigo tem como objetivo descrever o delineamento e procedimentos metodológicos adotados pelo Estudo Longitudinal sobre Estilo de Vida e Saúde em Estudantes Universitários (ELESEU). O estudo tem como base uma coorte dinâmica de estudantes universitários matriculados em tempo integral em uma universidade pública no Estado de Mato Grosso, Brasil. A coorte teve início em 2015 e terá quatro anos de seguimento, com a conclusão prevista para 2018. Um questionário auto-administrado contém perguntas sobre características demográficas e socioeconômicas e informações sobre condições de saúde e fatores de risco, tais como estilo de vida, estresse percebido, sintomas de depressão, imagem corporal, comportamentos de risco para transtornos alimentares, auto-percepção da saúde e qualidade da dieta e outras questões relacionadas à nutrição e saúde. Também são registradas medidas antropométricas e de pressão arterial. São coletados dois recordatórios alimentares de 24 horas e medidas de colesterol, triglicerídeos e glicose capilar em 50% dos estudantes. Em 2015, 495 participantes (82,6% dos estudantes elegíveis) foram avaliados no estudo de linha de base. Destes, 348 (70,3%) foram reavaliados em 2016. Em 2016, 566 participantes foram incluídos na coorte (81% dos estudantes elegíveis). O estudo ajudará a identificar fatores que possam influenciar mudanças na saúde nutricional e estado metabólico de adultos jovens durante a vida universitária.


La admisión a la universidad puede provocar cambios significativos en el patrón de exposición a los riesgos de salud. El objetivo de este trabajo es describir el diseño del estudio y los procedimientos metodológicos adoptados en el Estudio Longitudinal sobre Estilo de Vida y Salud de Estudiantes Universitario (ELESEU). Este estudio examina una cohorte dinámica de estudiantes a tiempo completo en una universidad pública en el estado de Mato Grosso, Brasil. Esta investigación, que empezó en 2015, tendrá 4 años de seguimiento y está previsto que finalice en 2018. Se utiliza un cuestionario autoadministrado, que contiene preguntas respecto a las características demográficas y socioeconómicas, e información sobre condiciones de salud y factores de riesgo tales como: estilo de vida, estrés percibido, síntomas de depresión, imagen corporal, riesgo de desórdenes en el comportamiento alimenticio, autoevaluación de salud y calidad de la dieta, así como otros asuntos relacionados con la nutrición y la salud. Las medidas antropométricas, así como la toma de presión arterial también fueron recogidas. Se recogieron dos encuestas alimentarias de 24-horas, análisis de colesterol, triglicéridos, y muestras de glucosa capilar en un 50% de los estudiantes. En 2015, 495 participantes (un 82,6% de los estudiantes elegibles) fueron evaluados en este estudio de referencia. De ellos, a 348 (un 70,3%) se les realizó un seguimiento en 2016. En 2016, 566 participantes fueron incluidos en la cohorte (81% de los estudiantes elegibles). Este estudio nos ayudará a identificar los factores que tal vez influencien en cambios nutricionales, de salud, y metabólicos en el estado de adultos jóvenes durante su vida universitaria.


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Adulto Jovem , Estudantes/estatística & dados numéricos , Universidades , Estilo de Vida , Brasil , Estado Nutricional , Inquéritos e Questionários , Fatores de Risco , Estudos Longitudinais , Síndrome Metabólica , Comportamento Alimentar
9.
Protein Expr Purif ; 132: 97-107, 2017 04.
Artigo em Inglês | MEDLINE | ID: mdl-28161544

RESUMO

Proteins extracted from Capsicum annuum L. fruits were initially subjected to reversed-phase chromatography on HPLC, resulting in eight peptide-rich fractions. All the fractions obtained were tested for their ability to inhibit porcine trypsin and amylase from both human saliva and from larval insect in vitro. All fractions were also tested for their ability to inhibit growth of the phytopathogenic fungi. Several fractions inhibited the activity of human salivary amylase and larval insect amylase, especially fraction Fa5. No fraction tested was found to inhibit trypsin activity, being Fa2 fraction an exception. Interestingly fraction Fa5 also displayed high antimicrobial activity against the species of the Fusarium genus. Fraction Fa5 was found to have two major protein bands of 17 and 6.5 kDa, and these were sequenced by mass spectrometry. Two peptides were obtained from the 6.5-kDa band, which showed similarity to antimicrobial peptides. Fraction Fa5 was also tested for its ability to permeabilize membranes and induce ROS. Fraction Fa5 was able to permeabilize the membranes of all the fungi tested. Fungi belonging to the genus Fusarium also showed an increase in the endogenous production of ROS when treated with this fraction. Antimicrobial peptides were also identified in the fruits from other Capsicum species.


Assuntos
Anti-Infecciosos , Capsicum/química , Inibidores Enzimáticos , Frutas/química , Fusarium/crescimento & desenvolvimento , Peptídeos , Proteínas de Plantas , alfa-Amilases/antagonistas & inibidores , Animais , Anti-Infecciosos/química , Anti-Infecciosos/isolamento & purificação , Anti-Infecciosos/farmacologia , Inibidores Enzimáticos/química , Inibidores Enzimáticos/isolamento & purificação , Inibidores Enzimáticos/farmacologia , Humanos , Peptídeos/química , Peptídeos/isolamento & purificação , Peptídeos/farmacologia , Proteínas de Plantas/química , Proteínas de Plantas/isolamento & purificação , Proteínas de Plantas/farmacologia , Suínos
10.
Ciênc. Saúde Colet ; 22(2): 369-382, Fev. 2017. tab
Artigo em Português | LILACS-Express | LILACS | ID: biblio-890250

RESUMO

Resumo Estudo transversal, baseado em dados do sistema de monitoramento por inquérito telefônico - VIGITEL, com o objetivo de estimar a prevalência e os fatores associados ao consumo recomendado de frutas, legumes e verduras (FLV) em 6696 indivíduos com idade ≥ 18 anos, de ambos os sexos, residentes na Região Centro-Oeste do Brasil, em 2012. O consumo recomendado foi a variável dependente e variáveis sociodemográficas, comportamentais e relacionadas à saúde foram as independentes. A prevalência do consumo recomendado de FLV foi de 26,3%, sendo maior entre as mulheres (RPaj = 1,44; IC95% = 1,29-1,62). A regressão de Poisson entre o desfecho e as variáveis independentes mostrou maior prevalência do consumo recomendado entre as mulheres residentes no Distrito Federal, casadas e que consideravam seu estado de saúde como bom/muito bom. Em ambos os sexos, observou-se associação direta do desfecho com a escolaridade, idade e prática de atividade física e associação inversa com o consumo de alimentos não saudáveis. Devido à baixa prevalência do consumo recomendado de FLV na população da Região Centro-Oeste do Brasil no ano de 2012, propõe-se que as estratégias de intervenção para melhorar o consumo desses alimentos sejam feitas de forma globalizada.


Abstract This is a cross-sectional study based on data from the VIGITEL telephone health monitoring survey, aiming to describe the prevalence of adequate fruit, greens and vegetable intake and to identify associated factors. This population-based study included 6696 individuals aged ≥ 18 years, living in the Midwest of Brazil, in 2012. The adequate consumption of fruit, greens and vegetables (FGV) was the dependent variable and sociodemographic, behavioral and health factors were the independent variables. The prevalence of adequate FGV consumption was 26.3%, being higher among women (RPaj = 1.44; CI95% = 1.29-1.62). The Poisson regression showed that the adequate consumption of FGV was higher among women resident in the Federal District, married and who considered their own health as good/very good. In both genders there was a direct association with education, age and physical activity and inversely associated with the consumption of unhealthy foods. Due to the low prevalence of adequate fruit, greens and vegetable intake in the population of Brazil's Midwest region in 2012, it is proposed that the intervention strategies to increase the consumption of these foods should be encouraged in a global manner.

11.
Biochim Biophys Acta Gen Subj ; 1861(1 Pt A): 3429-3443, 2017 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-27614033

RESUMO

BACKGROUND: Plant defensins were discovered at beginning of the 90s'; however, their precise mechanism of action is still unknown. Herein, we studied ApDef1-Saccharomyces cerevisiae interaction. METHODS: ApDef1-S. cerevisiae interaction was studied by determining the MIC, viability and death kinetic assays. Viability assay was repeated with hydroxyurea synchronized-yeast and pretreated with CCCP. Plasma membrane permeabilization, ROS induction, chromatin condensation, and caspase activation analyses were assessed through Sytox green, DAB, DAPI and FITC-VAD-FMK, respectively. Viability assay was done in presence of ascorbic acid and Z-VAD-FMK. Ultrastructural analysis was done by electron microscopy. RESULTS: ApDef1 caused S. cerevisiae cell death and MIC was 7.8µM. Whole cell population died after 18h of ApDef1 interaction. After 3h, 98.76% of synchronized cell population died. Pretreatment with CCCP protected yeast from ApDef1 induced death. ApDef1-S. cerevisiae interaction resulted in membrane permeabilization, H2O2 increased production, chromatin condensation and caspase activation. Ascorbic acid prevented yeast cell death and membrane permeabilization. Z-VAD-FMK prevented yeast cell death. CONCLUSIONS: ApDef1-S. cerevisiae interaction caused cell death through cell cycle dependentprocess which requires preserved membrane potential. After interaction, yeast went through uncontrolled ROS production and accumulation, which led to plasma membrane permeabilization, chromatin condensation and, ultimately, cell death by activation of caspase-dependent apoptosis via. GENERAL SIGNIFICANCE: We show novel requirements for the interaction between plant defensin and fungi cells, i.e. cell cycle phase and membrane potential, and we indicate that membrane permeabilization is probably caused by ROS and therefore, it would be an indirect event of the ApDef1-S. cerevisiae interaction.


Assuntos
Caspases/metabolismo , Ciclo Celular/efeitos dos fármacos , Defensinas/farmacologia , Viabilidade Microbiana/efeitos dos fármacos , Estresse Oxidativo/efeitos dos fármacos , Proteínas de Plantas/farmacologia , Saccharomyces cerevisiae/citologia , Antifúngicos/farmacologia , Permeabilidade da Membrana Celular/efeitos dos fármacos , Peróxido de Hidrogênio/metabolismo , Cinética , Potenciais da Membrana/efeitos dos fármacos , Modelos Biológicos , Saccharomyces cerevisiae/efeitos dos fármacos , Saccharomyces cerevisiae/metabolismo , Saccharomyces cerevisiae/ultraestrutura
12.
Cien Saude Colet ; 20(6): 1815-24, 2015 Jun.
Artigo em Inglês, Português | MEDLINE | ID: mdl-26060959

RESUMO

Lipid disorders are risk factors for atherosclerotic disease and its control may reduce morbidity and mortality from coronary artery disease. Knowledge of the factors associated with this injury may subsidize campaigns to encourage change in the population's lifestyle. The objective of this study is to estimate the prevalence of dyslipidemia and to identify associated factors. Cross-sectional population-based study, with individual data from the Telephone Survey on Risk Factors and Protection for Chronic Diseases Surveillance System (VIGITEL). It included 7,975 individuals of both sexes, aged ≥ 18 years living in state capitals in the central-west of Brazil, in the year 2009. Associations were estimated using Poisson regression. The prevalence of dyslipidemia was 15%, increased with age (p = < 0.01) did and not differ significantly according to sex. After adjustments, the variables that were directly associated with the outcome were overweight (p = < 0.01), obesity (p = < 0.01) and self-rated health as poor (p = < 0.01). Regular consumption of bean (≥ 5 days/week) was inversely associated with the prevalence of dyslipidemia (p = < 0.01). The prevalence of dyslipidemia in the central-west of Brazil was increased with age and was associated with bean consumption, excess weight (overweight and obesity) and self-rated health as poor.


Assuntos
Autoavaliação Diagnóstica , Dislipidemias/diagnóstico , Dislipidemias/epidemiologia , Adolescente , Adulto , Idoso , Brasil/epidemiologia , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Fatores de Risco , Adulto Jovem
13.
Ciênc. saúde coletiva ; 20(6): 1815-1824, 06/2015. tab
Artigo em Português | LILACS | ID: lil-748379

RESUMO

As dislipidemias são fatores de risco para a doença aterosclerótica e seu controle poderá reduzir a morbidade hospitalar e a mortalidade por doença arterial coronariana. O objetivo do artigo é estimar a prevalência de dislipidemias e identificar fatores associados. Estudo de corte transversal de base populacional com dados individuais do Sistema de Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por Inquérito Telefônico (VIGITEL). Foram incluídos 7.975 indivíduos de ambos os sexos, com idade ≥ 18 anos, residentes nas capitais dos estados da Região Centro-Oeste do Brasil, no ano de 2009. As associações foram estimadas por meio da regressão de Poisson. A prevalência de dislipidemia foi de 15%, crescente com a idade (p = < 0,01) e não diferiu significativamente quanto ao sexo. Após ajustes, as variáveis que se associaram diretamente com o desfecho foram: sobrepeso (p = < 0,01), obesidade (p = < 0,01) e a autoavaliação do estado de saúde ruim (p = < 0,01). O consumo regular de feijão (≥ 5 dias/semana) associou-se inversamente com a prevalência de dislipidemias (p = < 0,01). A prevalência de dislipidemia na Região Centro-Oeste foi crescente com a idade e associada ao consumo de feijão, excesso de peso (sobrepeso e obesidade) e autoavaliação do estado de saúde ruim.


Lipid disorders are risk factors for atherosclerotic disease and its control may reduce morbidity and mortality from coronary artery disease. Knowledge of the factors associated with this injury may subsidize campaigns to encourage change in the population's lifestyle. The objective of this study is to estimate the prevalence of dyslipidemia and to identify associated factors. Cross-sectional population-based study, with individual data from the Telephone Survey on Risk Factors and Protection for Chronic Diseases Surveillance System (VIGITEL). It included 7,975 individuals of both sexes, aged ≥ 18 years living in state capitals in the central-west of Brazil, in the year 2009. Associations were estimated using Poisson regression. The prevalence of dyslipidemia was 15%, increased with age (p = < 0.01) did and not differ significantly according to sex. After adjustments, the variables that were directly associated with the outcome were overweight (p = < 0.01), obesity (p = < 0.01) and self-rated health as poor (p = < 0.01). Regular consumption of bean (≥ 5 days/week) was inversely associated with the prevalence of dyslipidemia (p = < 0.01). The prevalence of dyslipidemia in the central-west of Brazil was increased with age and was associated with bean consumption, excess weight (overweight and obesity) and self-rated health as poor.


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Adulto Jovem , Autoavaliação Diagnóstica , Dislipidemias/diagnóstico , Dislipidemias/epidemiologia , Brasil , Estudos Transversais , Prevalência , Fatores de Risco
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