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1.
Rev. Cient. CRO-RJ (Online) ; 5(1): 17-23, Jan.-Apr. 2020.
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1123537

RESUMO

Objective: To evaluate the antimicrobial activity of antibiotic pastes used in lesion sterilization and tissue repair (LSTR) technique, through a novel membrane direct contact methodology against a multispecies biofilm and to establish appropriate dilutions for this method. Methods: CTZ (chloramphenicol, tetracycline, zinc oxide) and two formulations of 3Mix pastes (ciprofloxacin, metronidazole, and minocycline), 3Mix1 and 3Mix3, were evaluated with negative (0.9% saline) and positive (chlorhexidine 0.2%) control groups. Candida albicans and Enterococcus faecalis (24-hour) biofilms (n=10) grown on cellulose membranes were directly exposed to standardized amounts of fresh pastes and control solutions (n=2) for 24h. Membranes were immersed in 900 µl of saline solution, and seven serial dilutions were made for each sample. Plating for each dilution (n=2) was performed on culture media for microbial colony-forming unit (CFU) counting of total microorganisms, Candida spp. and Enterococcus spp. Aiming the comparison between groups, CFU quantification data were transformed into log10 CFU / mL and the Mann-Whitney test was applied (p<0.05). Results: Inhibition of CFU was observed for all pastes, with greatest effects for CTZ paste in medium selective for Candida spp. (p<0.001) and 3Mix1 in non-selective (p<0.000) and selective for Enterococcus spp. (p<0.004). Conclusion: The pastes showed antimicrobial activity against the tested multispecies biofilm, and the proposed direct contact methodology was efficient. Moreover, the dilutions used proved to be appropriate for this methodology.


Objetivo: Avaliar a atividade antimicrobiana de pastas antibióticas utilizadas na técnica Lesion Sterilization and Tissue Repair (LSTR), através de nova metodologia de contato direto com membrana contra um biofilme multiespécies e estabelecer diluições adequadas para avaliação. Métodos: CTZ (cloranfenicol, tetraciclina,óxido de zinco) e duas formulações de pastas 3Mix (Ciprofloxacina, Metronidazol e Minociclina), 3Mix1 e 3Mix3, foram avaliadas, além dos grupos controle, negativo (solução salina a 0,9%) e positivo (clorexidina 0,2%). Biofilmes de Candida albicans e Enterococcus faecalis cultivados sobre membranas de celulose (n=10) durante24 h foram expostos diretamente em contato com quantidades padronizadas de pastas frescas e controles (n = 2) por 24 h. As membranas foram imersas em 900µL de solução salina e sete diluições seriadas foram obtidas por amostra. O plaqueamento para cada diluição (n = 2) foi realizado em meios de cultura para microrganismos totais e seletivos para Candida spp. e Enterococcus spp. para contagem de unidades formadoras de colônias (UFC). Para comparação entre grupos, os dados da contagem de UFC foram convertidos em log10 UFC / mL e o teste Mann-Whitney foi aplicado (p<0,05). Resultados: Observou-se inibição de UFC para todas as pastas, maior para CTZ no meio seletivo para Candida (p<0,001)e 3Mix1 nos demais meios (p<0,004). Conclusão: Concluiu-se que as pastas apresentaram atividade antimicrobiana contra o biofilme multiespécies testado e que a nova metodologia de contato direto proposta foi eficiente. Além disso, as diluições utilizadas mostraram-se adequadas para essa metodologia.


Assuntos
Endodontia , Tratamento do Canal Radicular , Preparações Farmacêuticas , Testes de Sensibilidade Microbiana , Anti-Infecciosos
2.
Prog Orthod ; 21(1): 26, 2020 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-32869136

RESUMO

BACKGROUND: Malocclusion is a highly prevalent public health problem, and several studies have shown its negative correlation with quality of life, self-esteem, and social perceptions. However, its association with bullying is still controversial. OBJECTIVES: To evaluate the relationship between malocclusion and bullying in children and adolescents. SEARCH METHODS: The databases used for the electronic researches were PubMed, Scopus, Lilacs/BBO, Web of Science, and Cochrane Library. Grey literature was reviewed through Open Grey literature with no language or date restrictions. Selection criteria, based on the PECO strategy, were considered eligible observational studies that included schoolchildren or adolescents (P) with malocclusion (E), compared to those with normal occlusion (C), in which the relationship between malocclusion and bullying was determined (O). DATA COLLECTION AND ANALYSIS: Risk of bias evaluation was made for the qualitative synthesis by the Fowkes and Fulton criteria. Data regarding the age of participants and types of malocclusion and of bullying were extracted among other reported data. The quality of the evidence analyzed was evaluated through the GRADE approach. RESULTS: From 2744 articles identified in databases, nine met the eligibility criteria and were included in present systematic review, of which two studies were judged with methodological soundness. The quality of the evidence was classified as very low due to very serious problems for "risk of bias" and "other considerations" and serious problems of "indirectness". The age of participants ranged from 9 to 34 years considering a cohort study, with a bullying recalling perspective. Malocclusion was both evaluated by researchers and self-reported by participants addressing dentofacial characteristics mostly related to the incisors relationship. All studies evaluated the verbal type of bullying, while 3 also considered physical type. Both types were reported as related to malocclusion, although the results showed that extreme maxillary overjet (> 4 mm, > 6 mm, > 9 mm), extreme deep overbite, and having space between anterior teeth or missing teeth were the types of malocclusion with the strongest relations to bullying. CONCLUSIONS: With very low certainty of evidence, the results of this systematic review suggest that conspicuous extreme malocclusion may be related to the occurrence of bullying among children and adolescents.


Assuntos
Bullying , Má Oclusão , Sobremordida , Adolescente , Criança , Estudos de Coortes , Humanos , Qualidade de Vida
3.
Odontology ; 2020 Jul 30.
Artigo em Inglês | MEDLINE | ID: mdl-32734501

RESUMO

Evaluate the cytocompatibility of Calen®/ZO, Calcicur®, Vitapex®, Endoflas®, and zinc oxide/eugenol-based (ZOE) root canal pastes (RCP) to human primary osteoblasts (HPO) through a simplified model for primary teeth. The model employed pipette tips filled with 0.037 g of paste, exposed to 185 µL of culture medium for 24 h (n = 6). Release of components was analysed by Proton Nuclear Magnetic Resonance Spectroscopy (1H-NMR). HPO were exposed to conditioned media for 24 h. Cell viability was assessed by cell density and metabolic activity, and release of interleukin 6 (IL-6), vascular endothelial growth factor (VEGF) and fibroblast growth factor (bFGF) by immunological assay. Physicochemical properties and antimicrobial efficacy were also evaluated. 1H-NMR spectra analysis showed similarity between ZOE, Endoflas®, Calcicur®, and Vitapex® compared to Calen®/ZO and positive control, which showed distinct released components. Calen®/ZO and Calcicur® exhibited high alkaline pH in all periods and showed similar solubility. Calen®/ZO, ZOE, and Vitapex® showed similar flow rate. Calen®/ZO, Calcicur®, and Vitapex® did not exhibit antimicrobial efficacy. Calen®/ZO presented cytotoxicity (p < 0.05). Pastes did not increase IL-6 release compared to control. Apart from Vitapex®, all pastes significantly induced VEGF/bFGF release. Interactive effects among released products may affect biological response to filling pastes. Calcicur®, ZOE, Endoflas® and Calen®/ZO presented good to moderate cytocompatibility, with low impact on pro-inflammatory cytokine release and induction of growth factors of interest to tissue repair. This simplified model, specific for the evaluation of the cytocompatibility of RCPs on primary teeth, suggests how these pastes might contribute to bone repair in clinical situations of apical periodontitis in children.

4.
Clin Oral Investig ; 24(9): 2959-2972, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32666347

RESUMO

OBJECTIVE: To assess whether lesion sterilization and tissue repair (LSTR) technique resulted in similar clinical and radiographic success outcomes as compared with pulpectomy in primary teeth. MATERIALS AND METHODS: Randomized clinical trials comparing LSTR with pulpectomy by means of clinical and radiographic parameters were included. Risk of bias was assessed using Cochrane methodology and the certainty of evidence was determined by GRADE. RESULTS: Six articles were included. Conventional pulpectomy was favored with respect to radiographic success frequency in the systematic review. Four studies were included in meta-analyses. Based on the clinical results at 6 months (RR = 0.99, 95% CI, 0.94-1.04, p = 0.67; I2 = 0%), 12 months (RR = 0.97, 95% CI, 0.90-1.04, p = 0.34; I2 = 0%), and 18 months (RR = 0.89, 95% CI, 0.77-1.04, p = 0.14; I2 = 0%) and radiographic findings at 6 months (RR = 0.91, 95% CI, 0.78-1.06, p = 0.23; I2 = 9%), 12 months (RR = 0.87, 95% CI, 0.65-1.18, p = 0.38; I2 = 64%), and 18 months (RR = 0.84, 95% CI, 0.69-1.02, p = 0.08; I2 = 0%), there was no difference observed regarding success between the two treatments. The quality of evidence ranged from moderate to very low. CONCLUSIONS: No difference between the LSTR and pulpectomy approaches could be confirmed by meta-analyses. The quality of evidence according to the GRADE scheme ranged from moderate to very low. CLINICAL RELEVANCE: The present meta-analyses could not demonstrate the superiority of one treatment over the other.

5.
Rev. Rede cuid. saúde ; 14(1): 62-76, jul,2020.
Artigo em Português | LILACS-Express | LILACS | ID: biblio-1116342

RESUMO

O bruxismo em crianças tem se tornado uma preocupação crescente nos últimos anos. É definido como uma atividade involuntária dos músculos mastigatórios caracterizada por apertar ou ranger os dentes e pode ser de dois tipos, do sono (BS) ou da vigília (BV). A prevalência do BS na população infantil varia de 5,9% a 49,6%.Fatores funcionais, estruturais e psicológicos podem estar envolvidos com a presença do bruxismo. O diagnóstico é feito por meio de questionários, exame clínico e exame de polissonografia, que é o padrão ouro. Por ser uma desordem de origem central e não periférica, o BS não tem cura. Logo, faz-se o controle, que abrange prevenção, abordagem e gerenciamento de consequências. Atualmente, são citadas na literatura inúmeras técnicas de manejo para oBS. Este trabalho tem o objetivo de revisar a literatura atual referente ao controle do BS em crianças e confeccionar uma cartilha informativa direcionada aos pais, expondo os benefícios da higiene do sono como controle basal do BS. Conclui-se que a higiene do sono, apesar de baixa evidência científica, é considerada a primeira linha de abordagem para o bruxismo do sono infantil.


Children bruxism has become a growing worry in the last years. It is defined as an involuntary activity of masticatory muscles characterized by tightening or gritting the teeth and can be of two types, sleep (SB) or wake (WB). The prevalence of SB in infant population varies from 5,9% to 49,6%. Functional, structural and psychological factors may be involved in the presence of bruxism. The diagnosis is made through questionnaires, clinical examination and polysomnography, which is the gold standard. Because it is a central and non-peripheral origin disorder, SB has no cure. Therefore, control is made, which includes prevention, approach and consequence management. Currently, numerous management techniques for SB are cited in the literature. This work aims to review the current literature regarding the control of SB in children and to make an informative booklet directed to parents, exposing the benefits of sleep hygiene as basal control of BS. It is concluded that sleep hygiene, despite low scientific evidence, is considered the first line of approach for children sleep bruxism.

6.
Int J Paediatr Dent ; 30(3): 381-389, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-31811738

RESUMO

BACKGROUND: Achieving a void-free root canal filling is a challenge in current clinical pulpectomy practice. AIM: To compare filling effectiveness and internal voids of root filling materials and obturation techniques in resin-prototyped primary incisors by micro-CT. DESIGN: Fifty prototypes were instrumented and randomly divided (n = 10) according to the filling materials (Vitapex® , ZOE, Calcicur® , Feapex, and Calen® -ZO) and obturation technique: lentulo or pressure syringe (n = 5). The specimens were micro-CT scanned (pixel size = 7.83 µm) and reconstructed, and the total volume of filled canal (%FC) and internal voids (%IV) of the bulk filling material was calculated. Kruskal-Wallis and Mann-Whitney tests were used to detect differences and interactions among groups. RESULTS: Calen® -ZO, Vitapex® , and ZOE showed similar %FC. Calcicur® showed lower %FC compared with Calen® -ZO, Vitapex® , and ZOE (P < .05) but similar to Feapex. No statistically significant differences in %FC between lentulo or pressure syringe were disclosed. Regarding %IV, Vitapex® , and Calen® -ZO performed better with syringe, although Calcicur® was better with lentulo. The number of voids in the obturation bulk was similar among materials, but always lower (P < .05) in syringe filled specimens. CONCLUSION: Vitapex® , Calen® -ZO, and ZOE outperformed Calcicur® and Feapex in %FC and if the syringe technique is used, %IV of the obturation bulk and presence of defects was lower.


Assuntos
Incisivo , Materiais Restauradores do Canal Radicular , Polímeros , Obturação do Canal Radicular , Dente Decíduo , Cimento de Óxido de Zinco e Eugenol
7.
Artigo em Inglês | LILACS-Express | LILACS, BBO - Odontologia | ID: biblio-1135481

RESUMO

Abstract Objective: To verify the concordance in the evaluation of the apical limit of obturation (ALO) in filled root canals of primary teeth between digital and visual methods. Material and Methods: Twenty periapical radiographs of endodontically treated primary teeth were digitalized and evaluated by an endodontics specialist (E1), a PhD pediatric dentist (E2), and a MSc general dentist (E3). Calibrated evaluators (Kappa = 1.00) analysed the images in a light-isolated environment two times (D1 and D2) with a one-week interval between evaluations. ALO scores were categorized as overfilled, flush-filled and underfilled. Results: The intra-rater reliability between methods was 0.82 (D1) and 0.75 (D2) for E1, 0.93 (D1 and D2) for E2, and 0.94 (D1 and D2) for E3. Inter-rater reliability ranged from 0.71 (E1 × E3) and 1.00 (E1 × E2) for the visual method to 0.76 (E1 × E3) and 0.88 (E1 × E2) for the digital method. Spearman correlation coefficients showed a similar ranking among the evaluators. There was greater disagreement among the underfilled and ideal scores. For all evaluators, the digital method favoured the identification of the ideal score. Conclusion: Both methods are suitable for the determination of the ALO of filled primary teeth and can be used in clinical practice.

8.
Braz Oral Res ; 33: e002, 2019 Feb 11.
Artigo em Inglês | MEDLINE | ID: mdl-30758402

RESUMO

This study evaluated clinical and radiographic twelve-month outcomes of root canal treatments (CT) with smear layer removal, performed in primary teeth, using two different root canal filling materials. Pulpectomy was performed on 27 primary teeth with necrosis or irreversible pulpitis, caused by dental caries or trauma, in 23 children (2-7 years old). A single trained operator performed the CT in a single visit in cases without periapical or interradicular radiolucency (PIR) or in multiple visits in cases with PIR. Participants were selected based on specific inclusion and exclusion criteria, and randomly allocated into two groups: Group 1 (G1) - iodoform paste (iodoform + camphorated parachlorophenol + ointment comprising prednisolone acetate 5.0 mg and rifamycin 1.5 mg); Group 2 (G2) - Calen®/ZO paste. Treated teeth were restored with composite resin immediately after the root canal filling. The outcomes were evaluated clinically and radiographically according to specific criteria. Two blinded and standardized evaluators assessed the radiographic outcomes. We used descriptive analyses due to the small sample size. CTs were performed due to caries lesions in 70.4% of the cases and due to trauma in 29.6%. Only one tooth of G1 was unsuccessful; hence, pulpectomy performance in both groups was not influenced by the filling material, nor by any other analyzed variable. The level of the root canal filling was better in the Calen®/ZO group. The clinical and radiographic twelve-month outcomes indicated successful treatment, independently of the root filling material used.


Assuntos
Hidróxido de Cálcio/uso terapêutico , Hidrocarbonetos Iodados/uso terapêutico , Pulpectomia/métodos , Materiais Restauradores do Canal Radicular/uso terapêutico , Tratamento do Canal Radicular/métodos , Óxido de Zinco/uso terapêutico , Criança , Pré-Escolar , Cárie Dentária/diagnóstico por imagem , Cárie Dentária/terapia , Feminino , Humanos , Masculino , Pomadas , Pulpite/diagnóstico por imagem , Pulpite/terapia , Radiografia Dentária , Reprodutibilidade dos Testes , Camada de Esfregaço/cirurgia , Traumatismos Dentários/diagnóstico por imagem , Traumatismos Dentários/terapia , Dente Decíduo , Resultado do Tratamento
9.
Int J Paediatr Dent ; 29(1): 50-57, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30264472

RESUMO

BACKGROUND: Efficient endodontic instrumentation of primary teeth is a challenge for paediatric dentists. AIM: To evaluate biomechanical outcomes of endodontic instrumentation with a reciprocating system in a polymer-prototyped primary maxillary central incisor. DESIGN: The specimen was systematically instrumented and micro-CT scanned before and after each file. The amount of debris, percentage of non-instrumented areas, removed dentin volume, and lower dentin thickness at specific points along the root canal were analyzed. RESULTS: A 10% increase in removed dentin volume was observed when R40 was compared to R25 (14.5% vs 4.2%). When comparing R50 with R40, this increase was only 3.4% (17.9% vs 14.5%). In the root cervical third, there was substantial reduction in dentin thickness with R50 (48.8%), followed by R40 (39.5%) and R25 (18.6%). There was no difference between R25 and R40 in the removal of dentin at the apical third (15.8%), while R50 resulted in 39.8% reduction in dentin thickness. Percentage of non-instrumented areas were the same for all files. Accumulated debris with R40 and R50 was the same (0.19 mm³) while for R25 was 0.11 mm³. CONCLUSIONS: The Reciproc® system was effective for instrumentation of a prototyped primary maxillary central incisor. The most suitable file for apical preparation was R40.


Assuntos
Incisivo/cirurgia , Dente Decíduo/cirurgia , Instrumentos Odontológicos , Dentina , Humanos , Maxila , Resultado do Tratamento
10.
Rev. Cient. CRO-RJ (Online) ; 4(3): 68-72, 2019.
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1052466

RESUMO

Introduction: In the pediatric dental clinic the impacted teeth can be observedeventually, which can lead to the development of occlusion disorders. Objective:This study aimed to report a clinical case in which the surgical technique ofulectomy was used in conjunction with orthodontic treatment to aid the eruptionof a maxillary central incisor. Case Report: Male patient, 13 years old, Angle ClassI in the mixed dentition stage, with the tooth 21 impacted and reduced space forits eruption due to the migration of adjacent teeth. Fixed appliance was mountedwith Edgewise brackets using 0.20" stainless steel archwire with tight omega andactive spring between teeth 11 and 22 to recover the space of 21, but the passiveeruption was not observed. A fibrous gingival tissue was found, which by palpationrevealed the incisal edge of the tooth 21. The patient was referred to a pediatricdental clinic for a ulectomy. The minimally invasive surgical procedure consistedof the excision of the gingival tissue that covered the crown of the tooth 21 allowingits eruption in the dental arch. After the surgery, the teeth erupted and correctiveorthodontic treatment continued. Conclusion: The ulectomy technique associatedwith orthodontic treatment allowed to reestablish conditions for the developmentof dentition with satisfactory aesthetic and functional characteristics.


Introdução: Eventualmente na clínica odontológica, pode ser observada aimpacção de dentes, que pode acarretar transtornos para o desenvolvimento daoclusão. Objetivo: Objetivou-se relatar um caso clínico no qual a técnica cirúrgicade ulectomia foi utilizada, associada ao tratamento ortodôntico para auxiliar aerupção dentária de um incisivo central superior. Relato de Caso: Paciente dosexo masculino, 13 anos de idade, Classe I de Angle na fase de dentição mista, comdente 21 incluso e espaço reduzido para sua erupção em função da migração dosdentes adjacentes. Foi montado aparelho fixo com bráquetes prescrição Edgewise,utilizando arco 0,20" aço inoxidável com ômega justo e mola ativa entre osdentes 11 e 22 para recuperação do espaço do 21, mas não observou-se a erupçãopassiva. Constatou-se presença de tecido gengival fibroso que, ao toque,evidenciava a borda incisal do referido dente. O paciente foi encaminhado paraclínica de Odontopediatria para a realização da ulectomia. O procedimentocirúrgico minimamente invasivo, consistiu na exérese do tecido gengival querevestia a coroa do dente 21 não irrompido, permitindo sua erupção no arcodentário. Após a cirurgia, o dente irrompeu e o tratamento ortodôntico corretivoprosseguiu. Conclusão: A técnica da ulectomia associada ao tratamentoortodôntico permitiu restabelecer condições para desenvolvimento da dentiçãocom características estético-funcionais satisfatórias.


Assuntos
Odontopediatria , Ortodontia , Erupção Dentária , Dente Impactado , Dentição Mista , Incisivo , Má Oclusão de Angle Classe I
11.
Braz. oral res. (Online) ; 33: e002, 2019. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-989476

RESUMO

Abstract This study evaluated clinical and radiographic twelve-month outcomes of root canal treatments (CT) with smear layer removal, performed in primary teeth, using two different root canal filling materials. Pulpectomy was performed on 27 primary teeth with necrosis or irreversible pulpitis, caused by dental caries or trauma, in 23 children (2-7 years old). A single trained operator performed the CT in a single visit in cases without periapical or interradicular radiolucency (PIR) or in multiple visits in cases with PIR. Participants were selected based on specific inclusion and exclusion criteria, and randomly allocated into two groups: Group 1 (G1) - iodoform paste (iodoform + camphorated parachlorophenol + ointment comprising prednisolone acetate 5.0 mg and rifamycin 1.5 mg); Group 2 (G2) - Calen®/ZO paste. Treated teeth were restored with composite resin immediately after the root canal filling. The outcomes were evaluated clinically and radiographically according to specific criteria. Two blinded and standardized evaluators assessed the radiographic outcomes. We used descriptive analyses due to the small sample size. CTs were performed due to caries lesions in 70.4% of the cases and due to trauma in 29.6%. Only one tooth of G1 was unsuccessful; hence, pulpectomy performance in both groups was not influenced by the filling material, nor by any other analyzed variable. The level of the root canal filling was better in the Calen®/ZO group. The clinical and radiographic twelve-month outcomes indicated successful treatment, independently of the root filling material used.

12.
Rev. Cient. CRO-RJ (Online) ; 3(3): 2-8, Sept.-Dec. 2018.
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1021962

RESUMO

Introduction: There is no consensus on the literature about the best root canal filling material for primary teeth. Objective: The aim of this study was to describe the root canal filling materials most widely used in clinical pediatric dentistry, showing the observed success rates. Sources of data: A search, limited to the last 10 years and, no language restriction, was performed in October 2018 in the PubMed, Cochrane and LILACS databases using the terms "pulpectomy" and "primary teeth". This narrative literature review included clinical and randomized controlled trials conducted on children who had undergone pulpectomy as root canal therapy, with at least six months of clinical and radiographic follow-up. Synthesis of data: A total of 254 papers were retrieved from the databases. After applying the inclusion and exclusion criteria, 25 papers were included in this review. Zinc oxide and eugenol (ZOE) based paste was still the most widely used root canal filling material for primary teeth in pediatric clinical research, showing an overall clinical and radiographic success ranging from 63.3% to 93.3%. Conclusion: ZOE based paste is still the most used material for root canal filling in primary teeth, although there is a trend in the use of iodoform with calcium hydroxide pastes, which show high frequencies of success.


Introdução: Não há consenso na literatura quanto ao material obturador ideal para canais radiculares de dentes decíduos. Objetivo : O objetivo deste estudo foi descrever os materiais obturadores para canais radiculares mais utilizados na clínica Odontopediátrica, mostrando os índices de sucesso observados. Fonte dos dados : Uma busca, limitada aos últimos 10 anos e sem restrição de idioma, foi realizada em outubro de 2018 nas bases de dados PubMed, Cochrane e LILACS usando os termos "pulpectomy" e "primary teeth". Esta revisão narrativa da literatura incluiu estudos clínicos controlados randomizados em crianças submetidas a pulpectomia como tratamento endodôntico, com, no mínimo, seis meses de acompanhamento clínico e radiográfico. Síntese dos dados : Foram recuperados nas bases de dados 254 artigos. Após a aplicação dos critérios de inclusão e exclusão um total de 25 artigos foram incluídos nesta revisão. A pasta à base de óxido de zinco e eugenol (OZE) foi o material obturador mais utilizado para canais radiculares de dentes decíduos em pesquisa clínica Odontopediátrica, mostrando sucesso clínico e radiográfico geral que variou de 63,3% a 93,3%. Conclusão : A pasta à base de óxido de zinco e eugenol é o material mais utilizado para a obturação de canais radiculares de dentes decíduos, embora exista uma tendência para a utilização de pastas à base de iodofórmio com hidróxido de cálcio, que apresentam altas frequências de sucesso.


Assuntos
Criança , Endodontia , Pulpectomia , Obturação do Canal Radicular , Tratamento do Canal Radicular , Dente Decíduo , Materiais Dentários
13.
Rev. Cient. CRO-RJ (Online) ; 3(2): 65-71, May-Aug. 2018.
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1021908

RESUMO

Introduction: Minimally invasive dental procedures are aimed at recovering function and aesthetics in a practical manner, providing excellent treatment options. Bulk-fill composites offer some benefits, such as placement in single increments up to 4-mm thickness, decreased polymerization shrinkage, and general reduction in clinical time, while keeping aesthetic properties similar to those of conventional composite resins. Objective: To report two clinical cases of class I restorations in permanent molars with dentin carious lesions (ICDAS 4) treated with bulk-fill composites using the occlusal stamp technique. Cases were followed up for 6 months and the restorations were evaluated according to the World Dental Federation (FDI) and Public Health Service (USPHS) criteria. Case report: Restorations were performed using the following materials: Case 1 ­ Filtek ™ bulk-fill flowable resin (3M ESPE) associated with Filtek Z350 XT resin (3M ESPE); Case 2 - Filtek bulk- ill packable resin (3M ESPE). Three blinded evaluators assessed the materials and techniques in the follow-up period. Results: Case 1 achieved the lowest scores by the FDI and USPHS criteria, presenting better aesthetic, functional, and biological properties. Conclusion: Both treatments were clinically satisfactory after 6 months. Bulk-fill composites are good materials, allowing for a fast, effective, and quality treatment for the pediatric patient.


Introdução: A evolução dos procedimentos operatórios minimamente invasivos possibilitou a recuperação da função e estética com praticidade, proporcionando tratamentos de excelência. Resinas bulk-fill apresentam vantagens: inserção em incrementos únicos de até quatro milímetros, menor contração de polimerização e redução do tempo clínico, mantendo propriedades estéticas semelhantes às resinas compostas convencionais. Objetivo : Relatar dois casos clínicos de restaurações classe I em lesão cariosa em dentina não cavitada (ICDAS 4), em molares permanentes, com resina bulk-fill utilizando a técnica da réplica oclusal. Adicionalmente, foi realizado o acompanhamento dos casos após seis meses, avaliando-se de acordo com os critérios World Dental Federation (FDI) e Public Health Service (USPHS). Relato : As restaurações foram realizadas utilizando-se os materiais: Caso 1: resina Filtek bulk-fill flow (3M ESPE) associada à resina de cobertura Filtek Z350 XT (3M ESPE); Caso 2: resina Filtek bulk-fill condensável (3M ESPE). Avaliações foram conduzidas por três avaliadores cegos em relação aos materiais e técnicas. Resultados : Caso 1 apresentou menores pontuações nos critérios FDI e USPHS, com melhores propriedades estéticas, funcionais e biológicas, comparado ao Caso 2. Conclusão : Ambos os tratamentos apresentaram resultados clínicos satisfatórios após 6 meses de avaliação. Resinas bulk- ill possibilitam um tratamento rápido, eficaz e de qualidade.


Assuntos
Odontopediatria , Resinas Compostas , Procedimentos Cirúrgicos Minimamente Invasivos , Restauração Dentária Permanente , Dente Molar
14.
Braz Dent J ; 29(2): 117-127, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29898056

RESUMO

This study evaluated comparatively two configurations (powder and putty) of a composite biomaterial based on PLGA (Poly(lactide-co-glycolide)/nanoescale hydroxyapatite (ReOss®, Intra-Lock International) through microscopic morphology, in vitro cytotoxicity, biocompatibility and in vivo response as a bone substitute. SEM and EDS characterized the biomaterials before/after grafting. Cytocompatibility was assessed with murine pre-osteoblasts. Osteoconductivity and biocompatibility were evaluated in White New Zealand rabbits. Both configurations were implanted in the calvaria of eighteen animals in non-critical size defects, with blood clot as the control group. After 30, 60 and 90 days, the animals were euthanized and the fragments containing the biomaterials and controls were harvested. Bone blocks were embedded in paraffin (n=15) aiming at histological and histomorphometric analysis, and in resin (n=3) aiming at SEM and EDS. Before implantation, the putty configuration showed both a porous and a fibrous morphological phase. Powder revealed porous particles with variable granulometry. EDS showed calcium, carbon, and oxygen in putty configuration, while powder also showed phosphorus. After implantation EDS revealed calcium, carbon, and oxygen in both configurations. The materials were considered cytotoxic by the XTT test. Histological analysis showed new bone formation and no inflammatory reaction at implant sites. However, the histomorphometric analysis indicated that the amount of newly formed bone was not statistically different between experimental groups. Although both materials presented in vitro cytotoxicity, they were biocompatible and osteoconductive. The configuration of ReOss® affected morphological characteristics and the in vitro cytocompatibility but did not impact on the in vivo biological response, as measured by the present model.


Assuntos
Substitutos Ósseos , Animais , Regeneração Óssea , Durapatita/química , Feminino , Masculino , Teste de Materiais , Camundongos , Microscopia Eletrônica de Varredura , Osteoblastos/citologia , Copolímero de Ácido Poliláctico e Ácido Poliglicólico/química , Pós , Coelhos , Espectrometria por Raios X
15.
Artigo em Inglês | MEDLINE | ID: mdl-29754856

RESUMO

The objective of this study was to report the clinical evaluation results and 3-dimensional (3-D) dental and craniofacial characteristics observed in 2 male patients with mucopolysaccharidosis type II. The patients were evaluated clinically (soft tissue evaluation, evaluation of occlusion, periodontal and dental examinations) and by using craniofacial computed tomography, with evaluation of 3-D images in ITK-Snap v. 2.2 (Penn Image Computing and Science Laboratory, Philadelphia, PA; http://www.itksnap.org/) and 3-D Slicer (http://www.slicer.org/) software. Mandibular 3-D volumetric label maps were built from computed tomography scans of both patients and compared through superimposition on a healthy patient's mandibular images. Clinically, the patients presented the following oral manifestations: macroglossia, total open bite and generalized diastemas, and absence of caries. Patient 1 showed dental calculus and bleeding at the gingival margin. Patient 2 showed bleeding at the gingival margin, a permanent maxillary left central incisor missing as a result of trauma, and impacted permanent mandibular left and right second molars. 3-D images showed wide arches, prominent antegonial notches, a narrow mandibular body in the region of the antegonial notches, bilateral severe condylar hypoplasia, and enlarged coronoid processes. 3-D imaging and superimpositions revealed oral and skeletal displacements, contributing to the identification of changes in the course of mucopolysaccharidosis type II in patients with a late diagnosis.

16.
Arch Oral Biol ; 91: 57-62, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29679886

RESUMO

OBJECTIVE: This study evaluated the cytotoxicity, antimicrobial activity and in vitro influence of new fluoridated nanocomplexes on dental demineralization. DESIGN: The nanocomplexes hydroxypropyl-ß-cyclodextrin with 1% titanium tetrafluoride (TiF4) and γ-cyclodextrin with TiF4 were compared to a positive control (TiF4), a blank control (without treatment) and negative controls (hydroxypropyl-ß-cyclodextrin, γ-cyclodextrin, deionized water), following 12- and 72-hour complexation periods. The cytotoxicity was assessed using the neutral red dye uptake assay at T1-15 min, T2-30 min and T3-24 h. A minimum bactericidal concentration (MBC) against Streptococcus mutans (ATCC 25175) was performed. Enamel blocks were exposed to an S. mutans biofilm, and the percentage of surface microhardness loss was obtained. Biocompatibility and microhardness data were analysed using ANOVA/Tukey tests (p < 0.05). RESULTS: At T1, the cell viability results of the nanocomplexes were similar to that of the blank control. At T2 and T3, the 72 h nanocomplexes demonstrated cell viability results similar to that of the blank, while the 12 h solutions showed results different from that of the blank (p < 0.05). All fluoridated nanocompounds inhibited S. mutans (MBC = 0.25%), while the MBC of TiF4 alone was 0.13%. All fluoridated compounds presented a percentage of surface microhardness loss lower than that of deionized water (p < 0.05). CONCLUSIONS: The new fluoridated nanocomplexes did not induce critical cytotoxic effects during the experimental periods, whilst they did show bactericidal potential against S. mutans and inhibited enamel mineral loss.


Assuntos
Biofilmes/efeitos dos fármacos , Esmalte Dentário/efeitos dos fármacos , Fluoretos/farmacologia , Streptococcus mutans/efeitos dos fármacos , Desmineralização do Dente/prevenção & controle , 2-Hidroxipropil-beta-Ciclodextrina/farmacologia , Anti-Infecciosos/farmacologia , Linhagem Celular/efeitos dos fármacos , Sobrevivência Celular/efeitos dos fármacos , Cárie Dentária/tratamento farmacológico , Cárie Dentária/prevenção & controle , Fibroblastos/efeitos dos fármacos , Dureza , Humanos , Teste de Materiais , Testes de Sensibilidade Microbiana , Minerais , Nanotecnologia , Fosfatos , Propriedades de Superfície , Titânio/farmacologia , gama-Ciclodextrinas/farmacologia
17.
Rev. Cient. CRO-RJ (Online) ; 3(1): 3-7, Jan.-Apr. 2018.
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1021018

RESUMO

Introduction: Adolescents present a potential risk for the development of caries and periodontal diseases. Objective: The objective of the present study was to review the indicators of self-care and oral health in brazilian adolescents. Methodology: The search strategy (adolescent AND oral health) AND Brazil* was used in Pubmed and LILACS databases. Articles published between 2012 and 2017 that presented data on self-care and oral health of brazilian adolescents were included in this review. Synthesis of data: 837 and 1375 articles were retrieved from the Pubmed and LILACS databases, respectively. After applying the inclusion and exclusion criteria, 7 articles were included. The characteristics of the studies and the data obtained regarding sel-care and oral health of the adolescents were presented descriptively. Most of the studies included adolescents between the ages of 15 and 19 years, the majority of whom sought dental care in less than one year of the interview and caries was the most prevalent disease compared to gingival bleeding. Conclusion: According to the indicators of self-care evaluated, the majority of Brazilian adolescents reported having sought dental care in less than one year and caries disease was the most prevalent condition.


Introdução: Adolescentes apresentam potencial risco para o desenvolvimento das doenças cárie e periodontal. Objetivo: O objetivo do presente estudo foi revisar, na literatura, dados acerca da saúde oral de adolescentes brasileiros através da prevalência ou presença de cárie e sangramento gengival, como indicadores indiretos (consequências), e frequências de escovação dentária, uso de fio dental e visita odontológica como indicadores diretos deautocuidado oral. Fontes dos dados: Utilizou-se a estratégia de busca ((adolescent AND oralhealth) AND Brazil*) nas bases de dados PubMed e LILACS. Os artigos publicados entre setembro 2012-2017 que apresentaram dados de ao menos um dos indicadores de saúde oral e autocuidado em adolescentes brasileiros, foram incluídos nesta revisão. As características dos estudos e os dados obtidos foram apresentados de forma descritiva. Síntese dos dados: Foram recuperados nas bases de dados PubMed e LILACS 837 e 1375 artigos, respectivamente. Após a aplicação dos critérios de inclusão e exclusão, 10 artigos foram incluídos. A maioria dos estudos incluiu adolescentes entre 15 e 19 anos, com relato de atendimento odontológico realizado em menos de 1 ano antes da entrevista, sendo a cárie a alteração bucal mais prevalente. Conclusão: Dentro das limitações do presente estudo, de acordo com os dados obtidos através dos indicadores de autocuidado pesquisados, os adolescentes brasileiros mostraram cárie como o agravo observado mais prevalente; as frequências de escovação e uso de fio dental variaram na região Sul; e relataram atendimento odontológico no período inferior a um ano da entrevista.


Assuntos
Saúde Bucal , Autocuidado , Prevalência , Cárie Dentária
18.
Braz. dent. j ; 29(2): 117-127, Mar.-Apr. 2018. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-951529

RESUMO

Article This study evaluated comparatively two configurations (powder and putty) of a composite biomaterial based on PLGA (Poly(lactide-co-glycolide)/nanoescale hydroxyapatite (ReOss®, Intra-Lock International) through microscopic morphology, in vitro cytotoxicity, biocompatibility and in vivo response as a bone substitute. SEM and EDS characterized the biomaterials before/after grafting. Cytocompatibility was assessed with murine pre-osteoblasts. Osteoconductivity and biocompatibility were evaluated in White New Zealand rabbits. Both configurations were implanted in the calvaria of eighteen animals in non-critical size defects, with blood clot as the control group. After 30, 60 and 90 days, the animals were euthanized and the fragments containing the biomaterials and controls were harvested. Bone blocks were embedded in paraffin (n=15) aiming at histological and histomorphometric analysis, and in resin (n=3) aiming at SEM and EDS. Before implantation, the putty configuration showed both a porous and a fibrous morphological phase. Powder revealed porous particles with variable granulometry. EDS showed calcium, carbon, and oxygen in putty configuration, while powder also showed phosphorus. After implantation EDS revealed calcium, carbon, and oxygen in both configurations. The materials were considered cytotoxic by the XTT test. Histological analysis showed new bone formation and no inflammatory reaction at implant sites. However, the histomorphometric analysis indicated that the amount of newly formed bone was not statistically different between experimental groups. Although both materials presented in vitro cytotoxicity, they were biocompatible and osteoconductive. The configuration of ReOss® affected morphological characteristics and the in vitro cytocompatibility but did not impact on the in vivo biological response, as measured by the present model.


Resumo Este estudo avaliou comparativamente duas configurações (pó e massa) de um biomaterial composto com base de PLGA (Poli(láctico-co-glicólico)/hidroxiapatita em nanoescala (ReOss®, Intra-Lock International) através da morfologia microscópica, citotoxicidade in vitro, biocompatibilidade e resposta in vivo como substituto ósseo. MEV e EDS caracterizaram os biomateriais antes/após o enxerto. A citocompatibilidade foi avaliada em pré-osteoblastos murinos. A osteocondutividade e a biocompatibilidade foram avaliadas em coelhos Branco da Nova Zelândia. Ambas as configurações foram implantadas na calvária de dezoito animais em defeitos não-críticos, com coágulo sanguíneo como grupo controle. Após 30, 60 e 90 dias, os animais foram eutanasiados e os fragmentos contendo os biomateriais e controles coletados. Blocos ósseos foram embebidos em parafina (n=15) destinados às análises histológica e histomorfométrica, e em resina (n=3) destinadas à MEV e EDS. Antes da implantação, a configuração massa mostrou ambas fases morfológicas porosa e fibrosa. O pó revelou partículas porosas com granulometria variável. EDS mostrou cálcio, carbono e oxigênio na configuração massa, enquanto o pó mostrou também fósforo. Após a implantação a EDS revelou cálcio, carbono e oxigênio em ambas configurações. Os materiais foram considerados citotóxicos pelo teste XTT. A análise histológica mostrou nova formação óssea e nenhuma reação inflamatória nos sítios de implante. Entretanto, a análise histomorfométrica indicou que a quantidade de osso neoformado não foi estatisticamente diferente entre os grupos experimentais. Embora ambos os materiais tenham apresentado citotoxicidade in vitro, foram biocompatíveis e osteocondutores. A configuração do ReOss® afetou as características morfológicas e a citocompatibilidade in vitro, porém não impactou a resposta biológica in vivo, como medido pelo presente modelo.

19.
Spec Care Dentist ; 38(1): 51-54, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29314214

RESUMO

We described herein the oral and craniofacial features of a 7-year-old boy, diagnosed in utero with mucopolysaccharidosis II (MPS II), who was treated with hematopoietic stem cell transplantation (HSCT) at 70 days of age. The main oral clinical findings were the following: macroglossia, posterior cross-bite, crowding, pointed cuspid teeth, delayed tooth eruption, retained primary teeth, and enamel hypoplasia. The image examination showed: retention eruption, posterior primary teeth with short roots, absence of some permanent teeth, and stretching of the stylohyoid processes bilaterally. This patient showed the importance of early diagnosis and HSCT therapy in attenuating the clinical and radiographic oral and craniofacial manifestations of the MPS II patient.


Assuntos
Transplante de Células-Tronco Hematopoéticas , Anormalidades da Boca/etiologia , Mucopolissacaridose II/complicações , Mucopolissacaridose II/terapia , Criança , Humanos , Masculino
20.
Braz Oral Res ; 31: e41, 2017 Jun 05.
Artigo em Inglês | MEDLINE | ID: mdl-28591238

RESUMO

Dental caries is an oral pathology associated with both lifestyle and genetic factors. The caries process can be influenced by salivary composition, which includes ions and proteins. Studies have described associations between salivary protein polymorphisms and dental caries experience, while others have shown no association with salivary proteins genetic variability. The aim of this study is to assess the influence of salivary protein polymorphisms on the risk of dental caries by means of a systematic review of the current literature. An electronic search was performed in PubMed, Scopus, and Virtual Health Library. The following search terms were used: "dental caries susceptibility," "dental caries," "polymorphism, genetics," "saliva," "proteins," and "peptides." Related MeSH headings and free terms were included. The inclusion criteria comprised clinical investigations of subjects with and without caries. After application of these eligibility criteria, the selected articles were qualified by assessing their methodological quality. Initially, 338 articles were identified from the electronic databases after exclusion of duplicates. Exclusion criteria eliminated 322 articles, and 16 remained for evaluation. Eleven articles found a consistent association between salivary protein polymorphisms and risk of dental caries, for proteins related to antimicrobial activity (beta defensin 1 and lysozyme-like protein), pH control (carbonic anhydrase VI), and bacterial colonization/adhesion (lactotransferrin, mucin, and proline-rich protein Db). This systematic review demonstrated an association between genetic polymorphisms and risk of dental caries for most of the salivary proteins.


Assuntos
Suscetibilidade à Cárie Dentária/genética , Cárie Dentária/genética , Polimorfismo Genético , Proteínas e Peptídeos Salivares/genética , Índice CPO , Feminino , Estudos de Associação Genética , Marcadores Genéticos , Humanos , Masculino , Fatores de Risco
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