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Khirurgiia (Mosk) ; (6): 88-93, 2019.
Artigo em Russo | MEDLINE | ID: mdl-31317946


Optimal surgical strategy for secondary tricuspid regurgitation is still under discussion. First of all, this is due to rare organic disease of tricuspid valve and tricuspid regurgitation is almost always classified as secondary insufficiency. Fibrous annulus enlargement of tricuspid valve is the most common cause of tricuspid regurgitation. Annular dilatation may by the result of left ventricular failure due to myocardial or valvular diseases, right ventricular enlargement, pressure or volume overload. No surgical correction of tricuspid insufficiency during cardiac surgery for other leading disease aggravates short- and long-term results. Considering the wide interest and disputes around optimal surgical strategy for tricuspid regurgitation, this review is devoted to modern methods of surgical treatment of secondary tricuspid insufficiency.

Anuloplastia da Valva Cardíaca/métodos , Insuficiência da Valva Tricúspide/cirurgia , Valva Tricúspide/cirurgia , Dilatação Patológica/etiologia , Dilatação Patológica/cirurgia , Humanos , Insuficiência da Valva Tricúspide/etiologia
Anesteziol Reanimatol ; 60(2): 4-7, 2015.
Artigo em Russo | MEDLINE | ID: mdl-26148353


PURPOSE: To determine the specifics of inhaled iloprost effect on pulmonary and systemic hemodynamics in patients with pulmonary hypertension (PH) associated with left ventricular systolic dysfunction. MATERIALS AND METHODS: 47 vasore- activity tests (VRT) with 20 micrograms inhaled iloprost (Ventavis, Bayer) were performed in 39 candidates on heart transplantation. All patients had heart failure III-IV NYHA and PH with pulmonary vascular resistance (PVR) more than 2.5 Wood units. Hemodynamic parameters were evaluated at baseline and 15 minutes after inhalation of iloprost. RESULTS: Iloprost significant decreased PAPmean: from 36.8 ± 8.5 mm Hg to 29.9 ± 9.4 mm Hg (p < 0.001). There was a significant decrease in PVR:from 4.5 1.6 Wood units to 3 ± 1 Wood units (p < 0.001). PVR dropped more than 20% in 34 cases (72.3%). Iloprost inhalation caused significant changes in systemic hemodynamic. There were decrease in sys- temic vascular resistance (SVR)from 1820 ± 527 dynes·sec·cm(-5) to 1423 ± 427 dynes·sec·cm(-5) (p < 0.001), increase in stroke volume index (SVI) from 26.1 ± 8.7 ml/m2 to 30.5 ± 9.5 ml/m2 (p < 0.001) and decrease in PCWP from 20.6 ± 5.9 mm Hg to 18.4 ± 6.6 mm Hg. (p = 0.016). We found significant negative correlation between systemic effects of iloprost and initial cardiac index (r = -0.63). CONCLUSIONS: Inhaled iloprost caused significant changes in systemic hemodynamic when was used in patients with severe LV systolic dysfunction. Favorable changes in the left ventricle preload and after- load naturally increased its performance and decreased PCWP.

Hemodinâmica/efeitos dos fármacos , Hipertensão Pulmonar/fisiopatologia , Iloprosta/farmacologia , Vasodilatadores/farmacologia , Disfunção Ventricular Esquerda/fisiopatologia , Administração por Inalação , Pressão Sanguínea/efeitos dos fármacos , Feminino , Transplante de Coração , Humanos , Hipertensão Pulmonar/complicações , Hipertensão Pulmonar/tratamento farmacológico , Iloprosta/administração & dosagem , Masculino , Pessoa de Meia-Idade , Circulação Pulmonar/efeitos dos fármacos , Pressão Propulsora Pulmonar/efeitos dos fármacos , Índice de Gravidade de Doença , Resultado do Tratamento , Resistência Vascular/efeitos dos fármacos , Vasodilatadores/administração & dosagem , Disfunção Ventricular Esquerda/complicações , Disfunção Ventricular Esquerda/tratamento farmacológico
Vestn Otorinolaringol ; (5): 29-32, 2007.
Artigo em Russo | MEDLINE | ID: mdl-18163076


Anterior active rhinomanometry (AARM) was used for objective investigation of nasal respiration in patients with nasal bone fractures. Twenty one patients with nasal septum deformation have undergone reconstructive septorhinoplasty in acute trauma, 33 patients -- standard nasal bone reposition. AARM proved its efficacy as a simple and convenient method of nasal obstruction assessment in acute trauma and can be successfully applied for determination of therapeutic policy and control of surgical intervention. Most patients with nasal bone fracture had preoperative low total volume flow and elevated nasal resistance. Nasal septum curvature and deformation of external nose structures are of importance in development of the pathology. One-stage reconstruction of the nasal septum and pyramid in acute trauma brings about significantly better long-term functional results compared to conventional closed nasal bone reposition.

Fraturas Ósseas/fisiopatologia , Osso Nasal/lesões , Transtornos Respiratórios , Rinomanometria/métodos , Rinoplastia/métodos , Doença Aguda , Adolescente , Adulto , Criança , Fraturas Ósseas/diagnóstico por imagem , Humanos , Pessoa de Meia-Idade , Osso Nasal/diagnóstico por imagem , Septo Nasal/lesões , Septo Nasal/cirurgia , Transtornos Respiratórios/diagnóstico , Transtornos Respiratórios/etiologia , Transtornos Respiratórios/fisiopatologia , Tomografia Computadorizada por Raios X
Med Parazitol (Mosk) ; (1): 21-5, 2006.
Artigo em Russo | MEDLINE | ID: mdl-16562745


The present paper presents the epidemiological and clinicoimmunological aspects of the outburst of trichinosis in the Krymsky District of the Krasnodar Territory in January 2001. Six hundred and forty-eight persons ate infested wild boar meat, 119 (74.8%) fell ill with moderate and severe trichinosis. The authors provide the results of 3.5-year immunological studies of the patients with trichinosis and convalescents, infection-risk and healthy individuals; those of autopsies of the corpses of those who died from accidental causes unassociated with trichinosis, as well as examinations of domestic, synanthropic, and wild animals. The findings indicate that there is a focus of trichinosis with the low level of endemia in the Krymsky District of the Krasnodar Territory.

Anticorpos Anti-Helmínticos/sangue , Surtos de Doenças , Carne/parasitologia , Trichinella spiralis/imunologia , Triquinelose/epidemiologia , Adolescente , Adulto , Idoso , Animais , Criança , Pré-Escolar , Feminino , Testes de Hemaglutinação , Humanos , Técnicas Imunoenzimáticas , Masculino , Pessoa de Meia-Idade , Federação Russa/epidemiologia , Estudos Soroepidemiológicos , Sus scrofa , Trichinella spiralis/isolamento & purificação , Triquinelose/diagnóstico
Vestn Rentgenol Radiol ; (1): 23-5, 2004.
Artigo em Russo | MEDLINE | ID: mdl-15462051


The thyroid was ultrasonographically studied in 384 pre-term babies aged 4-8 days of life. The sizes of thyroid lobes were determined; the echogenicity of the thyroid was compared with that of the parotid salivary gland. The infants were born by apparently healthy mothers and females with iodine deficiency. An original procedure for neonatal ultrasound study was developed. Data statistical processing yielded a formula of the individual standard of a thyroid volume, which allows neonatal goiter and thyroid hypoplasia to be established at early stages of life.

Doenças da Glândula Tireoide/congênito , Doenças da Glândula Tireoide/diagnóstico por imagem , Glândula Tireoide/diagnóstico por imagem , Fatores Etários , Índice de Apgar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Ultrassonografia
Bull Exp Biol Med ; 135(6): 545-7, 2003 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12937669


The role of the autonomic nervous system in the development of ischemic cardiac arrhythmias was studied in acute experiments on cats receiving thyrotropin-releasing hormone. Bilateral vagotomy attenuated, while bilateral transection of cardiac branches of the stellate ganglia completely abolished the antiarrhythmic effect of thyrotropin-releasing hormone.

Arritmias Cardíacas/metabolismo , Sistema Nervoso Autônomo/fisiologia , Isquemia Miocárdica/metabolismo , Hormônio Liberador de Tireotropina/metabolismo , Animais , Antiarrítmicos/uso terapêutico , Arritmias Cardíacas/tratamento farmacológico , Pressão Sanguínea/fisiologia , Gatos , Denervação , Gânglio Estrelado/cirurgia , Hormônio Liberador de Tireotropina/administração & dosagem , Hormônio Liberador de Tireotropina/uso terapêutico , Vagotomia