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1.
J Nanosci Nanotechnol ; 20(1): 143-154, 2020 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-31383149

RESUMO

Simple one-step solvothermal route was used to synthesize γ-Bi2O3 nanostructures. Well-defined nanoflowers and finite nanorods surface morphology of the samples were revealed. The physical characterization and material confirmation was explored by employing X-ray diffraction (XRD), Raman, photoluminescence (PL), and Fourier transform infrared (FTIR) studies. The optical bandgap of about 2.71 and 2.72 eV was observed for nanoflower and nanorods, respectively. The highest specific surface area of 0.877 m²/g with mesoporous feature was reported for nanoflower sample. The improved photocurrent of 12.47 µA/cm² was observed for the nanoflower photoanode with lowest internal resistance and the highest stability over 3600 s, with 87% retention in photocurrent was estimated from chronoamperometry (CA) study. The effective methyl orange degradation of MO as 94% was investigated by nanoflower photocatalyst. The synthesis of metastable γ-Bi2O3 nanostructures with hierarchical morphology to adapt as an efficient photoanode for solar water splitting and pollutant degradation applications was reported.

2.
Zootaxa ; 4622(1): zootaxa.4622.1.1, 2019 Jun 21.
Artigo em Inglês | MEDLINE | ID: mdl-31716284

RESUMO

The parasitic isopod family Cymothoidae Leach, 1818 of the India exclusive economic zone is reviewed. A total of 56 nominal species corresponding to 48 valid species belonging to sixteen genera are reviewed from 73 host species belonging to 35 families. Mothocya plagulophora (Haller, 1880), Nerocila depressa Milne Edwards, 1840, Nerocila loveni Bovallius, 1887, Nerocila trichiura (Miers, 1877), Norileca triangulata (Richardson, 1910) and Ryukyua globosa Williams Bunkley-Williams, 1994 are redescribed. Indusa pustulosa Pillai, 1954 is synonymised with Agarna malayi Tiwari, 1952; Cymothoa krishnai Jayadev Babu Sanjeeva Raj, 1984 is synonymised with Cymothoa eremita (Brünnich, 1783) and Nerocila priacanthusi Kumari, Rao Shyamasundari, 1987 is synonymised with Nerocila arres Bowman Tareen, 1983. Ourozeuktes bopyroides (Lesueur, 1814) is revised and excluded from the Indian fauna. The Indian cymothoid species Agarna bengalensis Kumari, Rao Shaymasundari, 1990, Cymothoa asymmetrica Pillai, 1954 and Nerocila hemirhamphusi Shyamasundari, Rao Kumari, 1990 are regarded here as species inquirenda. A key to the Indian genera of the family Cymothoidae and keys to the Indian species of the genera Cymothoa, Joryma, Mothocya, and Nerocila are presented. A checklist of the valid Cymothoidae species until now reported from Indian marine fishes are compiled. Host preferences, morphological variability and distribution are discussed.


Assuntos
Isópodes , Parasitos , Animais , Crustáceos , Peixes , Especificidade de Hospedeiro , Índia
3.
Phys Rev E ; 99(6-1): 063107, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31330678

RESUMO

We investigate the role of intense vortical structures, similar to those in a turbulent flow, in enhancing collisions (and coalescences) which lead to the formation of large aggregates in particle-laden flows. By using a Burgers vortex model, we show, in particular, that vortex stretching significantly enhances sharp inhomogeneities in spatial particle densities, related to the rapid ejection of particles from intense vortices. Furthermore our work shows how such spatial clustering leads to an enhancement of collision rates and extreme statistics of collisional velocities. We also study the role of polydisperse suspensions in this enhancement. Our work uncovers an important principle, which, if valid for realistic turbulent flows, may be a factor in how small nuclei water droplets in warm clouds can aggregate to sizes large enough to trigger rain.

4.
Diagn Interv Imaging ; 100(11): 659-670, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31302074

RESUMO

A variety of dermatologic complications can occur after interventional radiology procedures, including fluoroscopy-induced radiation dermatitis, thermal skin injury from tumor ablation, non-target embolization to the skin, allergic reactions related to interventional radiology procedures, and dermatitis and infections at catheter sites. Yet, interventional radiologists typically lack training in dermatology. This review focuses on recognition of dermatologic complications and introduces basic principles for management of these complications. By taking a more active role in the diagnosis, management, and follow-up of dermatologic complications, interventional radiologists can improve the care for patients suffering iatrogenic skin inury.

5.
J Nanosci Nanotechnol ; 19(11): 7427-7435, 2019 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-31039908

RESUMO

We reported a simple and economical SDS (sodium dodecyl sulfate) assisted BiVO4 solvothermal synthesis of BiVO4 nanostructures. The implementation of pristine and SDS assisted BiVO4 nanostructure as photoanode in photoelectrochemical (PEC) water splitting was investigated. The good crystalline nature, defects present in the material, recombination nature and vibrational properties of the synthesized BiVO4 nanostructures have been analyzed and confirmed by XRD, Raman, PL and FTIR studies. The constructed nanoflower oriented morphology combined with nanorods for SDS assisted BiVO4 have been examined by SEM studies. The optical band gap differences were observed as 2.35 and 2.31 eV for pristine and SDS assisted BiVO4 nanostructures respectively. The higher photocurrent density of 5.8 µA/cm² at 0.5 V versus RHE with lower flat band potential of -0.75 V revealed for SDS assisted BiVO4 nanostructured photoanodes. Good conductivity, higher charge separation efficiency and 52% photocurrent retention under illumination was reported over 7200 s for the same efficient photoanode. These results suggested the substantial possibility of BiVO4 nanostructures synthesized by using SDS surfactant could be utilized as efficient photoanodes for PEC water splitting applications.

6.
J Nanosci Nanotechnol ; 19(6): 3429-3436, 2019 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-30744770

RESUMO

The SnO2 nanoparticles formation by hydrothermal method at different experimental conditions such as temperature, pH, reaction time, and capping agent (cetyltrimethylammonium bromide), was studied. X-ray diffraction results confirmed regular rutile crystal structure of SnO2. The characteristic Raman peak observed at 635 cm-1 corresponded to A1g modes of Sn-O vibrations. The study of optical property using photoluminescence confirmed the emissive spectra of SnO2. The infrared peak observed at 618 cm-1 corresponded to Eu modes of Sn-O vibrations of TO phonon because of E⊥ to c-axis. Scanning electron microscope images clearly revealed the formation of complete SnO2 nanoparticles. The unique SnO2 nanoparticles stacked together to form microspheres at pH-5 showed high specific capacitance of 274.8 F/g at a current density of 0.5 A/g. The observed results confirmed the feasibility of SnO2 nanoparticles being used as appropriate positive electrode candidate for supercapacitor applications.

7.
J Parasit Dis ; 42(3): 458-461, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30166796

RESUMO

Parasitic copepods infect a large number of fishes. In particular, the family Caligidae (Crustacea) comprises more than 450 species worldwide, some of which are harmful to cultured and wild fishes. Recently, we found a parasitic copepod on the host swordfish Xiphias gladius (Xiphidae) in the coastal waters of Parangipettai, southeast coast of India. It was identified as Gloiopotes huttoni by its morphological features, and it belongs to the family Caligidae (order Siphonostomatoida). The swordfish was highly infected with about 72 caligids on a single host. Both male and female forms of G. huttoni were colonized on the beak of the swordfish and distributed mostly along the upper and lower jaws of the host, with 42 and 30 copepod parasites, respectively. Most of the copepods were ovigerous, and more females than males were recorded. It is the first record of the occurrence of G. huttoni in India.

8.
Microb Pathog ; 125: 60-65, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30165115

RESUMO

Many naturally occurring biologically active compounds are derived from marine organisms. Brachyuran crab Dromia dehaani is also known as sponge crab. Hence, this study was undertaken to isolate and characterize the antimicrobial peptide from the marine crab hemolymph. Therefore the objectives of this research work was to high light the functions of biologically active peptide Dromidin. Dromidin was identified and confirmed as a new antimicrobial peptide in the hemolymph of the crab D. dehaani. Antimicrobial peptide was characterized and confirmed by using various analytical techniques. ESI-MS analysis of the active antimicrobial hemolymph fraction resulted in the value 513.0 Da. In addition, current findings strongly suggest that this peptide is functionally important against the pathogens.


Assuntos
Anti-Infecciosos/farmacologia , Peptídeos Catiônicos Antimicrobianos/farmacologia , Braquiúros/química , Animais , Anti-Infecciosos/química , Anti-Infecciosos/isolamento & purificação , Peptídeos Catiônicos Antimicrobianos/química , Peptídeos Catiônicos Antimicrobianos/isolamento & purificação , Organismos Aquáticos/química , Bactérias/efeitos dos fármacos , Fungos/efeitos dos fármacos , Hemolinfa/química , Testes de Sensibilidade Microbiana , Viabilidade Microbiana/efeitos dos fármacos , Peso Molecular , Espectrometria de Massas por Ionização por Electrospray
9.
Zookeys ; (769): 77-88, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29988720

RESUMO

The identity of the majid species of Paramaya De Haan, 1837, in the Indian Ocean is clarified with the collection of fresh specimens from the Bay of Bengal. Previously identified as P. spinigera (De Haan, 1837) which is known only from Japan, Taiwan, and Korea, the material from eastern India is here referred to a new species, P. mullisp. n. The new species can easily be distinguished from all congeners by its relatively shorter pseudorostral and carapace spines, more swollen branchial regions, distinctly granulated male thoracic sternum, and the G1 is not prominently curved with the dorsal projection on the sub distal part short and the tip rounded.

10.
Zootaxa ; 4378(1): 111-120, 2018 Feb 07.
Artigo em Inglês | MEDLINE | ID: mdl-29690020

RESUMO

Parilia alcocki Wood-Mason, in Wood-Mason Alcock, 1891, the type species of Parilia Wood-Mason, in Wood-Mason Alcock, 1891, described from the Bay of Bengal, is one of the largest known leucosioid crabs, reaching carapace widths of over 50 mm. It is, however, not well known and its male gonopods have never been figured. A series of specimens of this species obtained from a fishing port in Tamil Nadu, India, allows for a comprehensive re-description and illustrations of the species. Its distinguishing characters from congeners are discussed.


Assuntos
Braquiúros , Animais , Índia , Masculino
11.
Zootaxa ; 4526(2): 195-206, 2018 Nov 29.
Artigo em Inglês | MEDLINE | ID: mdl-30651524

RESUMO

Ryukyua circularis (Pillai, 1954) is recorded here for the first time on the host Amblygaster clupeoides Bleeker, 1849 from Indian waters. The species is redescribed with illustrations of the gravid female, adult male and manca from its type locality, and the known hosts and geographical records of the species are reviewed. Ryukyua circularis is readily identified from the oval to rounded body shape, widest at pereonite 3-5; cephalon deeply immersed in pereonite 1; mandible palp with the spiny surface, article 3 with a long terminal setae; pleonite 1-3 partially overlapped by a posterolateral margin of pereonite 7; pleotelson anterior lateral margins weakly convex, posterior margin evenly rounded, without median point.


Assuntos
Isópodes , Parasitos , Animais , Feminino , Peixes/parasitologia , Geografia , Índia , Masculino
12.
Endocrine ; 57(1): 156-165, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-28597198

RESUMO

BACKGROUND: Treating hypercortisolism in patients with Cushing's disease after failed surgery often requires chronic medication, underlining the need for therapies with favourable long-term efficacy and safety profiles. METHODS: In a randomised, double-blind study, 162 adult patients with persistent/recurrent or de novo Cushing's disease received pasireotide. Patients with mean urinary free cortisol at/below the upper limit of normal or clinical benefit at month 12 could continue receiving pasireotide during an open-ended, open-label phase, the outcomes of which are described herein. RESULTS: Sixteen patients received 5 years of pasireotide treatment. Among these, median (95% confidence interval) percentage change from baseline in mean urinary free cortisol was -82.6% (-89.0, -41.9) and -81.8% (-89.8, -67.4) at months 12 and 60. Eleven patients had mean urinary free cortisol ≤ upper limit of normal at month 60. Improvements in clinical signs were sustained during long-term treatment. The safety profile of pasireotide at 5 years was similar to that reported after 12 months. Fifteen of 16 patients experienced a hyperglycaemia-related adverse event; glycated haemoglobin levels were stable between months 6 and 60. Adverse events related to hyperglycaemia, bradycardia, gallbladder/biliary tract, and liver safety were most likely to first occur by month 6; adverse event severity did not tend to worsen over time. CONCLUSIONS: This represents the longest prospective trial of a medical therapy for Cushing's disease to date. A subset of patients treated with pasireotide maintained biochemical and clinical improvements for 5 years, with no new safety signals emerging. These data support the use of pasireotide as an effective long-term therapy for some patients with Cushing's disease.


Assuntos
Hipersecreção Hipofisária de ACTH/tratamento farmacológico , Somatostatina/análogos & derivados , Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Somatostatina/uso terapêutico , Resultado do Tratamento , Adulto Jovem
13.
J Parasit Dis ; 41(2): 593-595, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28615886

RESUMO

In the present study, occurrence of branchial parasitic cymothoid, Ryukyua circularis from the marine finfish, Amblygaster sirm is reported for the first time from Andaman Islands. Morphological characterization was carried out which confirmed the parasite as R. circularis. Molecular characterization using 28S rDNA revealed 443 bp sequence which has been submitted to NCBI GenBank under the accession no. KX090447. Ten female and one male parasite (R. circularis) were collected from the branchial cavity of the individual host fishes (A. sirm). The displacement of gill filament and cavity formation in the gill chamber of the host fish was observed. The report of this species from Andaman Islands gives further information on its geographic range extension, since they are currently known from West coast of India and Thailand.

14.
Inflammopharmacology ; 25(6): 621-631, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28378280

RESUMO

2-(4-phenylquinoline-2-yl)phenol derivatives (4a-l) with COX-2 enzyme inhibition, analgesic, anti-inflammatory and antipyretic potentials were executed and reported. From the in vitro COX-2 enzyme inhibition assay, compounds 4 h (IC50 0.026 µM) and 4j (IC50 0.102 µM) were found as most potent COX-2 inhibitors. Consequently, to get more insight into the binding mode with COX-2, compounds 4a-l were docked into the COX-2 (PDB ID: 1CX2) active site. In the Human Red Blood Cells (HRBC) membrane stabilization assay (in vitro anti-inflammatory), compounds 4f (IC50 0.064 µM) substituted with -OH (R1) and -3Cl (R2), 4 h (IC50 0.021 µM), 4i (IC50 0.484 µg/ml) and 4j (IC50 0.092 µM) with -CHO containing alkanol and ether group at R1 and -4F, -4Br and -OMe at R2 (C2) were showed most potent anti-inflammatory activity. Eventually, acute toxicity studies revealed that 2-(4-phenylquinoline-2-yl)phenol derivatives (4a-l) are safe up to a toleration dose limit of 100 µg/kg body weight. In the Backer's yeast intraperitoneal injection test, compounds 4f, 4 h and 4j produced significant (p < 0.05) antipyretic activity at 1, 1.5, 2 and 2.5 h, whereas test compound 4j and the reference drug indomethacin showed significant antipyretic activity throughout the observation period up to 2.5 h. Promising in vivo results obtained were correlated with the standard non-steroidal anti-inflammatory drugs and the compounds 4f, 4 h, 4i, 4j, and 4 l were efficiently identified as therapeutically potent/fortune moieties as non-steroidal anti-inflammatory agents/analgesics. At the end, ulcerogenic study result ensured that the tested 2-(4-phenylquinoline-2-yl)phenol derivatives created no side-effect.


Assuntos
Analgésicos/farmacologia , Anti-Inflamatórios/farmacologia , Inibidores de Ciclo-Oxigenase 2/farmacologia , Quinolinas/farmacologia , Bibliotecas de Moléculas Pequenas/farmacologia , Animais , Carragenina/farmacologia , Ciclo-Oxigenase 2/metabolismo , Eritrócitos/efeitos dos fármacos , Feminino , Humanos , Masculino , Fenóis , Ratos , Ratos Wistar
15.
J Parasit Dis ; 41(1): 55-61, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28316388

RESUMO

Isopods occur very commonly as parasites in food fishes. Parasitic isopods are typically marine and usually inhabit the warmer seas. They are blood-feeding; several species settle in the buccal cavity of fish, others live in the gill chamber or on the body surface including the fins. Isopods can cause morbidity and mortality in captive fish populations. The infestation usually pressure atrophy often accompanies the presence of larger parasites. The present study was aimed at collecting information on the neglected group of isopod parasites of the marine fishes from the Miri coastal environment, East Malaysia. A very little information available regarding the distribution of isopod parasites of Malaysian coastal environment. In the present study, nine isopod parasites were  oberved from ten marine fish species. The maximum number of parasites were observed in the months of June and October, 2013. Maximum prevalence was observed in October (50 %) and the minimum was observed in June (7.14 %). The parasitic infestation may lead to an economic loss in commercial fish species.

16.
Zookeys ; (716): 127-146, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29290711

RESUMO

A new species of deep-water oregoniid spider crab of the genus Pleistacantha Miers, 1879, is described from the Indian Ocean. The species is distinct in possessing a prominently inflated carapace in which the median parts of the branchial regions almost meet. It can also be distinguished from its closest congeners, P. moseleyi (Miers, 1885), P. pungens (Wood-Mason, in Wood-Mason & Alcock, 1891), and P. ori Ahyong & Ng, 2007, in its more elongate and less spinose chelipeds and ambulatory legs, shorter third maxilliped, trapezoidal male pleon and a male first gonopod which is relatively stout with a short subdistal dorsal papilla.

17.
Phys Rev E ; 94(1-1): 013105, 2016 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-27575215

RESUMO

The merger of two like-signed vortices is a well-studied problem, but in a turbulent flow, we may often have more than two like-signed vortices interacting. We study the merger of three or more identical corotating vortices initially arranged on the vertices of a regular polygon. At low to moderate Reynolds numbers, we find an additional stage in the merger process, absent in the merger of two vortices, where an annular vortical structure is formed and is long lived. Vortex merger is slowed down significantly due to this. Such annular vortices are known at far higher Reynolds numbers in studies of tropical cyclones, which have been noticed to a break down into individual vortices. In the preannular stage, vortical structures in a viscous flow are found here to tilt and realign in a manner similar to the inviscid case, but the pronounced filaments visible in the latter are practically absent in the former. Five or fewer vortices initially elongate radially, and then reorient their long axis closer to the azimuthal direction so as to form an annulus. With six or more vortices, the initial alignment is already azimuthal. Interestingly at higher Reynolds numbers, the merger of an odd number of vortices is found to proceed very differently from that of an even number. The former process is rapid and chaotic whereas the latter proceeds more slowly via pairing events. The annular vortex takes the form of a generalized Lamb-Oseen vortex (GLO), and diffuses inward until it forms a standard Lamb-Oseen vortex. For lower Reynolds number, the numerical (fully nonlinear) evolution of the GLO vortex follows exactly the analytical evolution until merger. At higher Reynolds numbers, the annulus goes through instabilities whose nonlinear stages show a pronounced difference between even and odd mode disturbances. Here again, the odd mode causes an early collapse of the annulus via decaying turbulence into a single central vortex, whereas the even mode disturbance causes a more orderly progression into a single vortex. Results from linear stability analysis agree with the nonlinear simulations, and predict the frequencies of the most unstable modes better than they predict the growth rates. It is hoped that the present findings, that multiple vortex merger is qualitatively different from the merger of two vortices, will motivate studies on how multiple vortex interactions affect the inverse cascade in two-dimensional turbulence.

18.
Int J Occup Environ Med ; 6(1): 7-19, 2015 01.
Artigo em Inglês | MEDLINE | ID: mdl-25588221

RESUMO

BACKGROUND: Work-related diseases contribute immensely to the global burden of diseases. Better understanding of attitudes of health care workers towards occupational safety and health (OSH) is important for planning. OBJECTIVE: To assess the attitude of medical students towards OSH around the globe. METHODS: A questionnaire assessing the attitude towards OSH was administered to medical and paramedical students of 21 Medical Universities across the globe. In the current study 1895 students, aged 18-36 years, from 17 countries were included. After having performed a principal components analysis, the associations of interest between the identified components and other socio demographic characteristics were assessed by multivariate linear regression. RESULTS: Principal component analysis revealed 3 components. Students from lower and lower-middle-income countries had a more positive attitude towards OSH, but the importance of OSH was still rated higher by students from upper-income countries. Although students from Asian and African continents showed high interest for OSH, European and South-Central American students comparatively rated importance of OSH to be higher. Paramedical students had more positive attitude towards OSH than medical students. CONCLUSION: The attitude of students from lower-income and lower-middle-income towards importance of OSH is negative. This attitude could be changed by recommending modifications to OSH courses that reflect the importance of OSH. Since paramedical students showed more interest in OSH than medical students, modifications in existing health care system with major role of paramedics in OSH service delivery is recommended.


Assuntos
Atitude do Pessoal de Saúde , Renda , Saúde do Trabalhador , Estudantes de Medicina , Adolescente , Adulto , Países Desenvolvidos , Países em Desenvolvimento , Feminino , Humanos , Masculino , Análise de Componente Principal , Faculdades de Medicina , Inquéritos e Questionários , Universidades , Adulto Jovem
19.
Artigo em Inglês | MEDLINE | ID: mdl-24704183

RESUMO

SIRT6 is a histone deacetylase that has been proposed as a potential therapeutic target for metabolic disorders and the prevention of age-associated diseases. Thus the identification of compounds that modulate SIRT6 activity could be of great therapeutic importance. We have previously developed an H3K9 deacetylation guided assay with SIRT6 coated magnetic beads (SIRT6-MB). With the developed assay, we identified quercetin, naringenin and vitexin as SIRT6 inhibitors from T. foenum-graecum seed extract using a candidate approach. Currently, the predominant method for the identification of active compounds from a plant extract is carried out through a dereplication process. A novel targeted approach for the direct identification of active compounds from a complex matrix could save time and resources. Herein, we report the application of the SIRT6-MB for 'fishing' experiments utilizing T. foenum-graecum seed extract. In which orientin, and seventeen other compounds were identified as SIRT6 binders. This is the first use of this method for 'fishing' out active ligands from a botanical matrix, and sets the basis for the identification of active compounds from a complex matrix.


Assuntos
Magnetismo/métodos , Imãs/química , Extratos Vegetais/química , Sirtuínas/metabolismo , Trigonella/química , Escherichia coli/metabolismo , Ligantes , Sementes/química
20.
J Mol Graph Model ; 49: 38-46, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-24491483

RESUMO

SIRT6 is a histone deacetylase that has been proposed as a potential therapeutic target for metabolic disorders and the prevention of age-associated diseases. We have previously reported on the identification of quercetin and vitexin as SIRT6 inhibitors, and studied structurally related flavonoids including luteolin, kaempferol, apigenin and naringenin. It was determined that the SIRT6 protein remained active after immobilization and that a single frontal displacement could correctly predict the functional activity of the immobilized enzyme. The previous study generated a preliminary pharmacophore for the quercetin binding site on SIRT6, containing 3 hydrogen bond donors and one hydrogen bond acceptor. In this study, we have generated a refined pharmacophore with an additional twelve quercetin analogs. The resulting model had a positive linear behavior between the experimental elution time verses the fit values obtained from the model with a correlation coefficient of 0.8456.


Assuntos
Quercetina/química , Quercetina/metabolismo , Sirtuínas/química , Sirtuínas/metabolismo , Sítios de Ligação , Humanos , Ligações de Hidrogênio
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