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J Tissue Viability ; 28(3): 161-166, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31128964


OBJECTIVE: The aim of this study was to evaluate the impact of High Voltage Pulsed Current (HVPC) on the integration of total skin grafts in rats submitted to nicotine action. MATERIALS AND METHODS: For this purpose, 60 adult Wistar rats randomly distributed in 6 groups of 10 animals were analyzed. The electrical stimulation (anodic and cathodic stimulation, motor level, 30 min at 10 Hz; minimum voltage 20 µs and 100 µs pulse interval) was applied for seven days, starting on the third day after surgery and after the dressing was removed from the graft. RESULTS: Anodic HVPC promoted greater graft integration, demonstrating a lower percentage of tissue contraction, a lower number of inflammatory infiltrates and a greater amount of vascular endothelial growth factor (VEGF), as well as a higher number of newly formed blood vessels. CONCLUSIONS: HVPC can positively influence the integration of skin grafts in nicotine-treated rats. anodic HVPC is shown to promote greater integration in relation to a lower percentage of tissue contraction, a lower number of inflammatory infiltrates and a greater amount of vascular endothelial growth factor and newformed blood vessels. Whereas, the cathodic polarity has presented smaller amount of tissue gap.

Terapia por Estimulação Elétrica/normas , Nicotina/efeitos adversos , Transplante de Pele/normas , Análise de Variância , Animais , Modelos Animais de Doenças , Terapia por Estimulação Elétrica/métodos , Terapia por Estimulação Elétrica/estatística & dados numéricos , Masculino , Nicotina/uso terapêutico , Ratos , Ratos Wistar/lesões , Transplante de Pele/métodos , Cicatrização/efeitos dos fármacos , Cicatrização/fisiologia
J Voice ; 29(2): 200-8, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25439510


OBJECTIVE: To verify the effect of the Transcutaneous Electrical Nerve Stimulation (TENS) and of Laryngeal Manual Therapy (LMT) and to compare the two techniques in relation to vocal/laryngeal symptoms, pain, and vocal quality after these resources were administered in dysphonic women. STUDY DESIGN: Control trial. METHOD: A total of 20 women with bilateral vocal nodules participated. All of the volunteers underwent investigation of vocal/laryngeal symptoms, musculoskeletal pain, and vocal register. The volunteers were subdivided into: 1. TENS Group (10 volunteers)-TENS application; 2. LMT Group (10 volunteers)-LMT application; both groups received 12 sessions of treatment, twice a week, lasting 20 minutes each. After treatment, the initial assessments were repeated. Data were statistically analyzed by Wilcoxon and signal test (P < 0.05). RESULTS: After TENS, there was significant improvement in the "high pitched voice" and "effort to speak" symptoms; there was significantly lower frequency of pain in the posterior neck and shoulder; TENS significantly reduced the intensity of pain in the posterior neck, shoulder, and upper back. The auditory perceptual analysis showed improvement only in the strain parameter after TENS. After LMT, there was improvement of the "sore throat," significantly lower incidence of pain in the anterior neck, and the pain intensity in the posterior neck decreased. CONCLUSION: When compared with the LMT, TENS appeared to be a treatment method intended to be used as a complement to voice therapy, considering the parameters evaluated and controlled.

Disfonia/terapia , Manipulações Musculoesqueléticas/métodos , Estimulação Elétrica Nervosa Transcutânea/métodos , Qualidade da Voz , Voz/fisiologia , Adulto , Disfonia/fisiopatologia , Feminino , Seguimentos , Humanos , Nervos Laríngeos/fisiopatologia , Laringe/fisiopatologia , Resultado do Tratamento