Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 94
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
2.
Middle East Afr J Ophthalmol ; 26(3): 178-180, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31619909

RESUMO

A 40-year-old woman presented with vitellieruptive stage of Best's vitelliform macular dystrophy (BVMD) in the right eye and pseudohypopyon stage in the left eye. She underwent comprehensive ophthalmic examination and fundus imaging using multicolor (MC) imaging technology of Spectralis (Heidelberg Engineering, Heidelberg, Germany) spectral-domain-optical coherence tomography system. Composite MC imaging revealed larger area of retinal pigment epithelium atrophy in vitellierruptive stage of the disease in the right eye compared to color fundus photograph. Retinal elevation in the pseudohypopyon stage was better delineated on composite MC and blue reflectance images in the left eye. Subretinal lipofuscin was best seen in green reflectance and short-wave autofluorescence images. The present case reports the MC imaging features of BVMD.

3.
Indian J Ophthalmol ; 67(10): 1678-1683, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31546507

RESUMO

Purpose: To describe treatment outcomes of eyes with pachychoroid neovasculopathy (PNV) with PDT and anti-(vascular endothelial growth factor) VEGF therapy. Methods: Retrospective interventional case series. Records of six consecutive cases of PNV were reviewed. Four cases were treated with PDT+ inj ranibizumab. Two cases underwent only PDT. Final visual outcomes and functional outcome including macular status and choroidal thickness were assessed. Results: We analysed six eyes of six patients with PNV. There were four males and two females. Mean age of the patients was 56.5 years. Mean duration of follow up was 8.2 months. All patients received reduced fluence PDT. Four patients received ranibizumab along with PDT; mean BCVA at presentation was 0.41 log MAR units and mean BCVA at final follow up was 0.44 log MAR units. There was significant improvement at final follow up (P = 0.03). Mean subfoveal choroidal thickness (SFCT) at presentation was 445 microns and mean SFCT at final follow up was 293 microns. There was a significant reduction at final follow up (P = 0.02). Conclusion: PDT with or without ranibizumab appears to be an effective treatment modality for PNV.

4.
J Assoc Physicians India ; 67(7): 34-37, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31559766

RESUMO

Objective: The study assessed the four-year incidence of diabetic peripheral neuropathy (DPN) and the risk factors that can predict incident neuropathy in a south Indian population with type 2 diabetes. Research Design and Methods: 1175 diabetic individuals were identified with known diabetes at baseline. At baseline, individuals underwent assessment of fasting plasma glucose and HbA1c levels, body mass index, waist-hip ratio, blood pressure, blood cholesterol and lipid levels, and ophthalmic evaluation including visual acuity, specular microscopy of the corneal endothelium, cataract grading and diabetic retinopathy assessment. Subjects were re-examined after four years for the assessment of incident neuropathy; 713 individuals were found eligible at follow-up. The presence of neuropathy was assessed at baseline and at follow-up and was defined as a Vibration Perception Threshold of ≥ 20 Volts. Results: : The four-year incidence of any neuropathy was 28.4%. Factors predictive of incident diabetic neuropathy were greater age at baseline (OR =1.068), higher body mass index (OR =1.034), presence of diabetic retinopathy (OR =4.879) and lower socioeconomic status (OR =4.841), when adjusted for several potential confounding factors. Conclusion: The four-year incidence of diabetic neuropathy in a south Indian population with type 2 diabetes is 28% and can be predicted by ophthalmic and clinical variables. These factors may be utilized in the assessment, monitoring and intervention in individuals with diabetes in an effort to prevent or delay the development of diabetic peripheral neuropathy.


Assuntos
Diabetes Mellitus Tipo 2/epidemiologia , Neuropatias Diabéticas/epidemiologia , Retinopatia Diabética/epidemiologia , Humanos , Incidência , Fatores de Risco
5.
Indian J Ophthalmol ; 67(9): 1470-1471, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-31436198
6.
Asia Pac J Ophthalmol (Phila) ; 8(4): 314-318, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31397675

RESUMO

PURPOSE: The aim of this study was to examine the hyperreflective dots seen in choroid on spectral domain optical coherence tomography (SDOCT) in eyes with diabetic macular edema (DME) and correlate it with visual acuity. DESIGN: Consecutive, cross-sectional case series of patients with DME between January 2017 and December 2017. METHODS: Eyes with DME having central foveal thickness ≥250 µm were included. SDOCT was performed using Spectralis system (Heidelberg Engineering, Germany). Hyperreflective choroidal foci (HCF) were defined as well-circumscribed dots within choroid having reflectivity equal to or higher than adjacent retinal pigment epithelium. HCF were counted manually within 1500 µm of fovea using a horizontal line scan by a blinded observer. Eyes were divided in 3 groups: group A (no HCF), group B (1-10 HCF), and group C (>10 HCF). RESULTS: One hundred nineteen eyes of 60 DME patients were included. Sixty (50.4%) eyes were in group A, whereas 42 (33.6%) and 17 (14.2%) eyes belonged to group B and group C, respectively. The mean logMAR best corrected visual acuity was significantly lower in group B (0.76 ±â€Š0.79) and C (1.2 ±â€Š0.78) as compared with group A (0.22 ±â€Š0.49) (P = 0.001). Mean central foveal thickness in group A (300.4 ±â€Š122.4 µm) was significantly lower than group B (455.52 ±â€Š209.1 µm) and group C (529.4 ±â€Š196.4 µm) with P value of 0.001. CONCLUSIONS: The present study describes HCF as novel prognostic SDOCT biomarker in DME whose presence denotes poor visual acuity. Further longitudinal studies are required to substantiate our findings.


Assuntos
Corioide/patologia , Retinopatia Diabética/complicações , Edema Macular/diagnóstico , Tomografia de Coerência Óptica/métodos , Acuidade Visual , Estudos Transversais , Retinopatia Diabética/diagnóstico , Feminino , Angiofluoresceinografia/métodos , Seguimentos , Fundo de Olho , Humanos , Edema Macular/etiologia , Masculino , Pessoa de Meia-Idade , Prognóstico , Epitélio Pigmentado da Retina/patologia , Estudos Retrospectivos , Índice de Gravidade de Doença
7.
Retina ; 39(8): e34-e35, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31259814
9.
J Neuroophthalmol ; 2019 Jul 08.
Artigo em Inglês | MEDLINE | ID: mdl-31295149

RESUMO

Myelinated nerve fibers (MNF) are characterized as whitish, relatively sharply demarcated, feather-like structures located in the retinal nerve fiber layer. MNF are located quite frequently in contiguity with the optic nerve head. This may lead to a diagnostic dilemma by preventing clear visualization of the optic disc margins. We herein describe the utility of multicolor imaging (MCI) in identifying optic disc anatomy in a case of MNF contiguous to the disc. MCI and infrared reflectance were superior to color fundus photography in delineating disc margins. Our pilot study describes the efficacy of MCI in delineating optic disc anatomy in a case of MNF.

11.
Indian J Ophthalmol ; 67(4): 566-568, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30900603

RESUMO

Acute macular neuroretinopathy (AMN) is a deep retinal ischemic manifestation. It has been reported after the use of sympathomimetics, childbirth, bee sting, oral contraceptives, flu-like illness, intravenous contrast agents and bodily trauma not directly involving the eyes. We report a case of AMN following blunt ocular trauma. An 18-year-old male presented with an acute history of blurring of vision following blunt trauma to the right eye. Spectral domain optical coherence tomography (SD-OCT) showed hyperreflectivity of the outer nuclear layer with ellipsoid layer disruption. This report highlights AMN as a manifestation of blunt trauma, presence of which may be an indicator of poor visual prognosis.


Assuntos
Traumatismos Oculares/complicações , Angiofluoresceinografia/métodos , Macula Lutea/patologia , Doenças Retinianas/etiologia , Tomografia de Coerência Óptica/métodos , Acuidade Visual , Ferimentos não Penetrantes/complicações , Doença Aguda , Adolescente , Anti-Inflamatórios/administração & dosagem , Traumatismos Oculares/diagnóstico , Seguimentos , Fundo de Olho , Humanos , Masculino , Soluções Oftálmicas , Prednisolona/administração & dosagem , Prednisolona/análogos & derivados , Doenças Raras , Doenças Retinianas/diagnóstico , Doenças Retinianas/tratamento farmacológico , Fatores de Tempo , Ferimentos não Penetrantes/diagnóstico
12.
Clin Exp Optom ; 102(4): 442, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30891823
15.
Indian J Ophthalmol ; 67(3): 412-414, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30777973

RESUMO

Interpretation of optic disc cupping and neuroretinal rim is challenging in myopic eyes because of large, shallow, and tilted disc, myopic crescent, and macular degeneration. Color and red-free optic disc photographs do not reveal the cup/disc ratio often in myopic eyes. We report characteristics of multicolor optic disc photography in three myopic eyes. All eyes underwent multicolor imaging Spectralis SDOCT system (Heidelberg Engineering, Germany). Owing to use of three laser lights in a confocal design, multicolor optic disc photography was able to delineate the neuroretinal rim and optic cup more clearly than color and red-free optic disc photographs.


Assuntos
Glaucoma de Ângulo Aberto/diagnóstico , Pressão Intraocular/fisiologia , Miopia/diagnóstico , Disco Óptico/patologia , Doenças do Nervo Óptico/diagnóstico , Fotografação/métodos , Acuidade Visual , Feminino , Glaucoma de Ângulo Aberto/complicações , Glaucoma de Ângulo Aberto/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Miopia/complicações , Miopia/fisiopatologia , Doenças do Nervo Óptico/etiologia , Reprodutibilidade dos Testes
16.
Ophthalmic Surg Lasers Imaging Retina ; 50(1): 8-15, 2019 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-30640390

RESUMO

BACKGROUND AND OBJECTIVE: To analyze the visibility of various diabetic retinopathy lesions in multicolor imaging (MCI) and compare them to corresponding color fundus photography (CFP). PATIENTS AND METHODS: Retrospective review of 130 eyes of 65 consecutive patients with diabetic retinopathy who underwent multicolor confocal scanning laser ophthalmoscopy and CFP. RESULTS: Hard exudates (Hex) were seen in 74 eyes (71.2%). In all 74 eyes, Hex were visible on both CFP and MCI. Among other color channels, Hex were picked up most in green reflectance (GR) images in 73 eyes (70.2%). Cotton-wool spots (CWS) were picked up in 29 eyes (27.9%) on MCI and in 27 eyes (26%) on CFP. In both GR and blue reflectance (BR) imaging, they were equally picked up in 29 eyes (27.9%). Retinal hemorrhages were picked up in 83 eyes (79.8%) on MCI and in 82 eyes (72.8%) on CFP. Among other channels, they were picked up most in GR images in 81 (77.9%) eyes. Hex, CWS, and hemorrhages were seen better on MCI and in GR images as compared to CFP, BR, and infrared imaging, respectively. With CFP as the comparator, the sensitivity and specificity of MCI to detect of these lesions were more than 90%. CONCLUSIONS: The authors' pilot study validates the efficacy of MCI in picking up lesions of DR vis a vis CFP. MCI has potential to replace CFP in clinical and DR screening setting. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:8-15.].


Assuntos
Retinopatia Diabética/diagnóstico , Angiofluoresceinografia/métodos , Oftalmoscopia/métodos , Fotografação/métodos , Retina/patologia , Tomografia de Coerência Óptica/métodos , Feminino , Seguimentos , Fundo de Olho , Humanos , Masculino , Projetos Piloto , Reprodutibilidade dos Testes , Estudos Retrospectivos , Adulto Jovem
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA