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Front Genet ; 10: 1172, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31803242


Chicken have a considerable impact in South American rural household economy as a source of animal protein (eggs and meat) and a major role in cultural traditions (e.g., cockfighting, religious ceremonies, folklore). A large number of phenotypes and its heterogeneity are due to the multitude of environments (from arid to tropical rain forest and high altitude) and agricultural systems (highly industrialized to subsistence agriculture). This heterogeneity also represents the successive introduction of domestic chicken into this continent, which some consider predating Columbus' arrival to South America. In this study, we have used next-generation restriction site-associated DNA sequencing to scan for genome-wide variation across 145 South American chickens representing local populations from six countries of South America (Colombia, Brazil, Ecuador, Peru, Bolivia, and Chile). After quality control, the genotypes of 122,801 single nucleotide polymorphisms (SNPs) were used to assess the genomic diversity and interpopulation genetic relationship between those populations and their potential sources. The estimated population genetic diversity displayed that the gamefowl has the least diverse population (θπ = 0.86; θS = 0.70). This population is also the most divergent (F ST = 0.11) among the South American populations. The allele-sharing analysis and the admixture analysis revealed that the current diversity displayed by these populations resulted from multiple admixture events with a strong influence of the modern commercial egg-layer chicken (ranging between 44% and 79%). It also revealed an unknown genetic component that is mostly present in the Easter Island population that is also present in local chicken populations from the South American Pacific fringe.

Case Rep Neurol Med ; 2015: 421923, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26605097


Central pontine myelinolysis (CPM) is classically attributed to overly rapid correction of profound hyponatremia. However, there are case reports of this disease in the setting of normal serum sodium or minimal hyponatremia. These cases have been hypothesized to be secondary to other metabolic disturbances such as hyperglycemia or hypophosphatemia. Eunatremic CPM has also been described in patients with advanced acquired immune deficiency syndrome (AIDS). The mortality risk in this special population is significantly higher than those with hyponatremia-associated CPM, but the mechanisms are unclear. We discuss a case of a man with AIDS who developed CPM with minimal hyponatremia and no other metabolic disturbances. Common variables within this population, such as hypoalbuminemia and lymphoma, are discussed as potential factors contributing to the pathophysiology. Reporting these atypical cases is crucial to our understanding of how to prevent future cases.

VozAndes ; 14(1): 68-71, feb. 2002. graf
Artigo em Espanhol | LILACS | ID: lil-311106


En Ecuador, las instituciones de salud han empezado a tomar en cuenta el uso de medidas universales y el manejo de desechos. Sin embargo hoy en día en los subcentros de salud toda la basura que es producida se coloca en recipientes sin ninguna discriminación. También se reutilizan guantes esterilizados principalmente por motivos económicos. Existen varios artículos que mencionan el correcto uso de las medidas universales. En este artículo enseñamos cuantos subcentros de salud conocían las precauciones universales y cuantos manejan la basura correctamente. Nosotros hicimos una encuesta entrevistando el personal de once subcentros de salud de la Porvincia de Sucumbíos. El 64 por ciento conocía de las medidas y el manejo...

Normas de Qualidade Ambiental , Resíduos de Serviços de Saúde