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1.
Rev. osteoporos. metab. miner. (Internet) ; 11(2): 55-63, abr.-jun. 2019. tab
Artigo em Espanhol | IBECS | ID: ibc-188337

RESUMO

Objetivo: La osteonecrosis de maxilares (ONM) es una enfermedad recientemente descrita cuya etiopatogenia es des‐conocida, aunque se ha atribuido, entre otras causas, al tratamiento prolongado con bifosfonatos. Sin embargo, mientras que la ONM es una patología localizada, la acción de los bifosfonatos es generalizada, es decir, afecta a todos los huesos. No hay estudios que muestren el estado óseo general de los pacientes con ONM. Con este trabajo hemos querido estudiaren pacientes afectos de ONM dicho estado general mediante medidas cuantitativas y estimaciones cualitativas del hueso por medio de la densidad mineral ósea (DMO) y el trabecular bone score(TBS) y los parámetros ultrasonográficos en el calcáneo (QUS), además de la presencia de otras enfermedades y la toma de fármacos (especialmente los bifosfonatos)en los pacientes con ONM que pudieran participar en su etiopatogenia. Material y método: Estudio observacional y transversal de casos y controles, realizado en 304 pacientes de ambos sexos, en los que el grupo de casos (grupo I) estaba formado por 24 pacientes que habían sufrido una ONM, mientras que el grupo control (grupo II) estaba formado por 280 pacientes que no presentaban ONM y que recibían bifosfonatos desde un mínimo de 5 años por causas diversas. A todos ellos se les realizó una densitometría ósea (DXA, Hologic 4500 Discovery(R)) en la columna lumbar y en la extremidad proximal del fémur. Además, se les realizó mediciones del TBS en la columna lumbar, así como de los parámetros ultrasonográficos en el calcáneo (Hologic, Sahara(R)...


Objetive: Osteonecrosis of the jaw (ONJ) is a recently reported disease whose origin and development are unknown, although prolonged bisphosphonate treatment has been attributed, among other causes. While ONJ is a localized condition, the action of bisphosphonates is widespread and affects all bones. No studies show the general bone status of patients with ONJ. Our study examines the general condition in patients with ONJ using quantitative measurements and qualitative estimates of bone by means of bone mineral density (BMD) and trabecular bone score (TBS) and ultrasound parameters in the calcaneus (QUS), along with other diseases and the taking of drugs (especially bisphosphonates) in patients with ONJ who may be involved in the pathogenesis. Material and method: Observational and cross‐sectional study of cases and controls, conducted in 304 patients of both sexes, in which the case group (group I) was formed by 24 patients who had suffered ONJ. The control group (group II)contained 280 patients who did not present ONJ and who received bisphosphonates over at least 5 years for various reasons. All of them underwent bone densitometry (DXA, Hologic 4500 Discovery®) in the lumbar spine and proximal femur. In addition, TBS measurements were made in the lumbar spine, as well as ultrasound parameters in the calcaneus (Hologic, Sa‐hara®) in the dominant foot (QUS). Results: Patients suffering ONJ presented greater comorbidity than controls, with a higher prevalence of diabetes mellitus, cancer, rheumatoid arthritis, hyperthyroidism, heart disease, arrhythmias, heart failure and hypercholesterolemia. There‐fore, the consumption of corticosteroids, (oral and inhaled), anticoagulants, hypnotics, bisphosphonates i.v. (zoledronate)...


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Osteonecrose/tratamento farmacológico , Doenças Maxilares/tratamento farmacológico , Difosfonatos/uso terapêutico , Estudos de Casos e Controles , Osteonecrose/diagnóstico por imagem , Doenças Maxilares/diagnóstico por imagem , Estudos Transversais , Densitometria , Absorciometria de Fóton
2.
Av. odontoestomatol ; 35(2): 69-72, mar.-abr. 2019. tab
Artigo em Espanhol | IBECS | ID: ibc-184310

RESUMO

Introducción: Los cepillos pueden albergar una amplia variedad de microorganismos, incluyendo bacterias hongos y virus, pudiendo así facilitar la translocación de especies en un mismo individuo y la transmisión de especies entre individuos. Métodos: Estudio de la contaminación bacteriana de los cepillos de dientes de cien voluntarios con la cumplimentación de un cuestionario (lugar de almacenamiento, tipo de cepillo, utilización de estuche de almacenamiento y meses de uso). Resultados: Se estudiaron un total de 100 muestras. El 33% guardaba el cepillo fuera del baño, un 20% lo guardaba en el cajón del baño y un 47% sobre el lavabo del baño. El 92% de las muestras estaban contaminadas como mínimo con un grupo de microorganismos Conclusión: El lugar de almacenamiento del cepillo de dientes es fundamental en la reducción de la contaminación. Se debe guardar en un lugar seco, lejos del inodoro y sin estuche


Introduction: Brushes can house a wide variety of microorganisms, including fungal bacteria and viruses, which can facilitate the translocation of species in the same individual and the transmission of species between individuals. Methods: Study of the bacterial contamination of toothbrushes of one hundred volunteers with the completion of a questionnaire (place of storage, type of brush, use of storage case and months of use). Results: A total of 100 samples were studied. 33% kept the brush outside the bathroom, 20% kept it in the bathroom drawer and 47% on the bathroom sink. 92% of the samples were contaminated with at least one group of microorganisms. Conclusion: The storage place of the toothbrush is fundamental in the reduction of contamination. It should be stored in a dry place, away from the toilet and without a box


Assuntos
Humanos , Masculino , Feminino , Adulto , Dispositivos para o Cuidado Bucal Domiciliar/microbiologia , Desinfecção , Estudantes de Medicina/estatística & dados numéricos , Higiene Bucal , Escovação Dentária/tendências , Estudos Transversais , Inquéritos e Questionários , Poluição Ambiental , Bacilos e Cocos Aeróbios Gram-Negativos/patogenicidade
3.
Neurologia ; 2018 Mar 08.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-29526317

RESUMO

INTRODUCTION: Recent studies on uric acid as a biomarker for the prognosis of acute stroke have found conflicting results. METHODS: We collected blood samples from 600 consecutively admitted patients at our tertiary hospital and analysed the relationship between uric acid levels and functional prognosis (measured using the modified Rankin Scale [mRS]). Patients who had received reperfusion therapy were excluded since this may have influenced uric acid levels. RESULTS: A total of 73% of patients had mRS scores ≤2; the mean uric acid level was 5.22mg/dL. We found a nonlinear relationship between functional prognosis at discharge and serum uric acid levels at admission when the National Institutes of Health Stroke Scale score was excluded from the analysis. CONCLUSIONS: Serum uric acid levels in patients with acute ischaemic stroke are significantly associated with functional prognosis at discharge, although this relationship is nonlinear. In fact, poorer prognosis is associated both with very low and with very high concentrations of uric acid. This suggests a dual role of uric acid in relation to stroke: on the one hand, as an associated risk factor, and on the other, as a possible neuroprotective factor due to its antioxidant effect.

4.
Artigo em Inglês | MEDLINE | ID: mdl-29031393

RESUMO

OBJECTIVE: To determine whether maternal diet supplementation with omega-3 long chain polyunsaturated fatty acids (omega-3 LC-PUFAs) during the last trimester of pregnancy and the breastfeeding period influences the levels of inflammatory cytokines in mother and infants. MATERIAL AND METHOD: This registered, double-blind randomized study included 46 pregnant women, who were randomly allocated to either an experimental group receiving 400mL/day of a fish oil-enriched dairy drink [320mg docosahexaenoic acid (DHA) + 72mg eicoapentaenoic acid] (FO group, n = 24) or to a control group receiving 400mL/day of a non-supplemented dairy drink (CT group, n = 22), from week 28 of pregnancy until the fourth month of lactation. During the study, maternal dietary patterns were monitored by a nutritionist, who encouraged compliance with current recommendations of fatty acids intake. DHA concentrations and cytokine levels (GM-CSF, IL-2, IL-4, IL-6, IL-10, INF-γ and TNF-α) were measured in maternal plasma at the moment of recruitment and in maternal (n = 46) and infant (n = 46) plasma at birth and 2.5 months after birth. RESULTS: Maternal plasmatic IL-4 levels were higher in FO than in CT subjects (p = 0.009). Additionally, a tendency was observed to higher IL-10 and IL-2 in the FO group. Plasmatic IL-6 however, was higher in CT mothers (p = 0.001). TNF-α was higher in CT infants at birth and 2.5 months after birth (p = 0.005). An analysis of possible relationships between DHA and the concentrations of different cytokines revealed negative correlation between maternal plasmatic IL-6 and DHA (higher plasmatic DHA corresponded to lower IL-6). CONCLUSIONS: Maternal dietary omega-3 LC-PUFAs supplementation during critical periods like pregnancy, lactation and early newborn development may influence the levels of certain inflammatory cytokines, reducing pro-inflammatory cytokines and promoting an anti-inflammatory "environment".


Assuntos
Ácidos Graxos Ômega-3/administração & dosagem , Fenômenos Fisiológicos da Nutrição Materna , Mães , Terceiro Trimestre da Gravidez/efeitos dos fármacos , Adulto , Aleitamento Materno , Criança , Citocinas/sangue , Suplementos Nutricionais , Ácidos Docosa-Hexaenoicos/sangue , Feminino , Óleos de Peixe/administração & dosagem , Humanos , Lactente , Recém-Nascido , Lactação/efeitos dos fármacos , Leite Humano/efeitos dos fármacos , Leite Humano/metabolismo , Gravidez , Terceiro Trimestre da Gravidez/sangue
5.
Rev. osteoporos. metab. miner. (Internet) ; 9(2): 55-61, abr.-jun. 2017. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-164165

RESUMO

Introducción: En los últimos años se han desarrollado varias herramientas de cálculo o escalas para valorar el riesgo de fractura por fragilidad a largo plazo. La calculadora Garvan no ha sido validada en la población española. El objetivo de este estudio fue observar su capacidad predictiva en una muestra de la población canaria y, por tanto, de la española. Material y métodos: Se incluyó a 121 pacientes a los que se les realizó un seguimiento de 10 años en nuestras consultas. A todos se les valoró el riesgo de fractura usando la calculadora Garvan y basándonos en los datos obtenidos en la primera visita realizada. Resultados: De los 121 pacientes, 30 sufrieron al menos una fractura osteoporótica a lo largo de los 10 años de seguimiento. El grupo de pacientes fracturados tenían en la escala Garvan un valor medio de riesgo de sufrir cualquier fractura por fragilidad de 27%, frente al 13% de aquellos que no sufrieron fractura (p<0,001). El área bajo la correspondiente curva ROC fue de 0,718 (IC-95% = 0,613 ; 0,824). En base a ella, se estimó que el punto de corte óptimo para considerar un alto riesgo de fractura por fragilidad fue 18,5%. A este valor le correspondió una sensibilidad de 0,67 (IC-95% = 0,47 ; 0,83) y una especificidad de 0,67 (IC-95% = 0,56 ; 0,77). Conclusiones: Nuestros resultados muestran que la escala Garvan predice adecuadamente el riesgo de fractura osteoporótica a 10 años en nuestra población. Un valor inferior a 18,5% permitiría establecer un riesgo de fractura bajo, pudiendo ser utilizada como herramienta de cribado (AU)


Introduction: Several calculation tools or scales have been developed in recent years to assess the risk of fracture due to long-term fragility. The Garvan calculator has not been validated in the Spanish population. This study aims to observe their predictive capacity in a population sample of the Canary Islands and, therefore, of the Spanish population. Material and Methods: We included 121 patients who were followed up for 10 years in our consultations. All were assessed the risk of fracture using the Garvan calculator and based on the data obtained in the first visit. Results: Of the 121 patients, 30 suffered at least one osteoporotic fracture over the 10-year follow-up period. The group of patients with fractures had on the Garvan scale an average risk value to suffer any fracturing fracture of 27%, compared to 13% of those who did not suffer fracture (p<0.001). The área under the corresponding ROC curve was 0.718 (CI-95% = 0.613 ; 0.824). Based on this, the estimated optimal cut-off point to consider a high risk fracture was 18.5%. This value corresponded to a sensitivity of 0.67 (CI-95% = 0.47 ; 0.83) and a specificity of 0.67 (CI-95% = 0.56 ; 0.77). Conclusions: Our results show that the Garvan scale adequately predicts the risk of 10-year osteoporotic fracture in our population. A value lower than 18.5% would allow us to establish a low fracture risk and could be used as a screening tool (AU)


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Valor Preditivo dos Testes , Fraturas Ósseas/epidemiologia , Fraturas Ósseas/prevenção & controle , Osteoporose/complicações , Osteoporose/diagnóstico , Fatores de Risco , Indicadores Básicos de Saúde , Fraturas por Osteoporose/epidemiologia , Fraturas por Osteoporose/prevenção & controle , Fraturas Ósseas/etiologia , Osteoporose/etiologia , Espanha/epidemiologia
6.
Int J Obes (Lond) ; 40(1): 10-3, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26499441

RESUMO

BACKGROUND: The question of whether breastfeeding protects the child from obesity is a still debated issue; however, the relationship between early adiposity rebound and higher risk of obesity is well known. This study was aimed at evaluating whether breastfeeding (without formula supplement) during the first 6 months of life delays the time of adiposity rebound and consequently reduces the rates of obesity at the age of 8. METHODS: This retrospective cohort study included 1812 children born in Gran Canaria in 2004, with follow-up until they were 8 years of age. Anthropometrical data had been taken during routine visits to the doctor and were extracted from medical record databases. Only children with breastfeeding for the first 6 months of life (173 children) and children without breastfeeding (192 children) were included. Children with mixed feeding and children whose data were not available were excluded. RESULTS: No body mass index (BMI) differences were found between children with breastfeeding (17.7) or without breastfeeding (17.3) during the first 6 months of life. The percentages of children with normal weight, overweight and obesity were similar in both groups, as well as the age of adiposity rebound breastfeeding 3.61 years; formula 3.64 years). Early adiposity rebound was associated with increased BMI at the age of 8, both in male and female children. CONCLUSIONS: Breastfeeding during the first 6 months of life was not demonstrated to delay the age of the adiposity rebound, in our study.


Assuntos
Aleitamento Materno/estatística & dados numéricos , Obesidade Pediátrica/epidemiologia , Adiposidade , Índice de Massa Corporal , Criança , Feminino , Seguimentos , Humanos , Lactente , Recém-Nascido , Masculino , Obesidade Pediátrica/prevenção & controle , Gravidez , Estudos Retrospectivos , Fatores de Risco , Espanha/epidemiologia , Ganho de Peso
7.
Rev. osteoporos. metab. miner. (Internet) ; 7(4): 107-111, nov.-dic. 2015. tab
Artigo em Espanhol | IBECS | ID: ibc-147373

RESUMO

Introducción: Los inhibidores de la bomba de protones (IBP) son fármacos ampliamente utilizados, si bien esto conlleva a un sobreuso que no es acorde con las indicaciones aceptadas en España y en el resto de Europa. Por otro lado, algunos autores han establecido una posible implicación de los IBP en el riesgo de fractura. Con este trabajo hemos pretendido efectuar una primera aproximación al conocimiento del consumo de IBP en nuestro medio y analizar para qué indicación son prescritos, a la vez que estudiar su posible asociación con un mayor riesgo de fractura por fragilidad entre sus consumidores. Material y método: Estudio observacional, transversal, abierto, descriptivo, en el que se entrevistó aleatoriamente a un número de pacientes que fueron atendidos en diferentes ámbitos sanitarios: consultas externas hospitalarias, servicios de urgencias, consulta de Atención Primaria y pacientes ingresados en planta hospitalaria. Resultados: De los 411 pacientes entrevistados, el 54% de los pacientes recibían IBP, y cuya edad media era de 63,3 años, frente al 46% que no los tomaban y que eran más jóvenes, con una edad media de 50,9 años. La distribución por sexos fue similar. La principal razón de utilizar el IBP era como “protector gástrico”, en el 39,8% de los pacientes, indicación no existente en la ficha técnica de este grupo de fármacos. Los consumidores de IBP tenían una mayor prevalencia de todas las fracturas por fragilidad. Conclusiones: Más de la mitad de la población encuestada consume IBP, y de ella cerca del 40% sin una indicación médica correcta. Por esto, unido a la mayor prevalencia de fracturas por fragilidad que presentan -que nos hace pensar en un posible mayor riesgo de fractura entre sus usuarios- consideramos la necesidad de un uso más racional de estos fármacos. Estas conclusiones son preliminares pero, a la vista de estos resultados, creemos que puede ser interesante realizar más estudios dirigidos a comprobar de manera más firme la relación entre los IBP y el riesgo de fractura osteoporótica (AU)


Introduction: Proton-pump inhibitors (PPIs) are widely used drugs, though it should be noted that excessive use is not in line with the accepted indications in Spain and throughout Europe. Furthermore, some authors have established a possible PPI link to the risk of fracture. In this paper, we make an initial approach to knowledge into PPI consumption and analyze what indication is prescribed. We also studied the drugs’ possible association with increased risk of fragility fracture in users. Material and method: An observational, transversal, open and descriptive study in which a number of randomly-chosen patients were interviewed. These patients had been treated in outpatient, emergency and primary care centers. Some had also been treated in hospital wards. Results: Of the 411 patients interviewed, 54% received PPIs. The average age was 63.3 years, compared with 46% that did not take them and who were younger presenting a mean age of 50.9 years. Gender distribution was similar. PPIs were mainly used as a “gastric protector”, in 39.8% of the patients, with no indication appearing in the technical specifications for this group of drugs. Consumers of PPIs presented a higher prevalence of all fragility fractures. Conclusions: More than half of the population surveyed consumed PPI. Of this group, about 40% did so without proper medical advice. Therefore, in addition to the higher prevalence of fragility fractures that suggest a possible increased risk of fracture among its users, we consider the need for a more rational use of these drugs. These preliminary findings point to a need for further studies to confirm the relationship between PPIs and the risk of osteoporotic fracture (AU)


Assuntos
Humanos , Inibidores da Bomba de Prótons/efeitos adversos , Osteoporose/induzido quimicamente , Doenças Ósseas Metabólicas/induzido quimicamente , Uso Indevido de Medicamentos sob Prescrição/efeitos adversos , Substâncias Protetoras/farmacocinética , Fraturas por Osteoporose/epidemiologia , Homocistinúria/epidemiologia , Ácido Gástrico
9.
An. pediatr. (2003, Ed. impr.) ; 81(2): 107-114, ago. 2014. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-126017

RESUMO

Introducción: La mayoría de los datos antropométricos de referencia utilizados en nuestro país proceden de estudios llevados a cabo fuera del mismo hace muchos años, o bien están basados en datos de un único o pocos centros. Además, el número de recién nacidos extremadamente prematuros (RNEP) incluidos ha sido muy escaso. Objetivos: Desarrollar unas tablas y gráficas de referencia poblacionales en nuestro país para el peso, la longitud y el perímetro craneal (PC), por edad gestacional y sexo, en RNEP de raza blanca procedentes de gestaciones únicas. Pacientes y métodos: Se incluyeron de todos los recién nacidos ≤ 28 semanas de EG, registrados sobre la base de los datos SEN1500 durante 10 años (2002-2011). La EG se estimó basándose en la ecografía fetal precoz o la fecha de la última regla. Los datos se analizaron mediante el paquete estadístico SPSS 20 y se crearon tablas percentiladas de referencia independientes para varones y mujeres, utilizando el método LMS de Cole y Green. Resultados: Se presentan las primeras tablas y gráficas percentiladas con base poblacional en nuestro país de peso, longitud y PC en RNEP, incluyendo recién nacidos al límite de viabilidad. Se objetiva un dimorfismo sexual desde las 23 semanas de gestación. Conclusiones: Estas nuevas referencias, específicas por sexo y de base poblacional, pueden ser útiles para mejorar la evaluación del crecimiento del prematuro extremo en nuestro país, así como para el desarrollo de estudios epidemiológicos, o evaluación de tendencias temporales y de intervenciones clínicas o de salud pública dirigidas a la optimización del crecimiento fetal. Un dimorfismo sexual es evidente desde etapas muy tempranas de la gestación (AU)


Introduction: Most anthropometric reference data for extremely preterm infants used in Spain are outdated and based on non-Spanish populations, or are derived from small hospital-based samples that failed to include neonates of borderline viability. Objectives: To develop gender-specific, population-based curves for birth weight, length, and head circumference in extremely preterm Caucasian infants, using a large contemporary sample size of Spanish singletons. Patients and methods: Anthropometric data from neonates ≤ 28 weeks of gestational age were collected between January 2002 and December 2010 using the Spanish database SEN1500. Gestational age was estimated according to obstetric data (early pregnancy ultrasound). The data were analyzed with the SPSS.20 package, and centile tables were created for males and females using the Cole and Green LMS method. Results: This study presents the first population-based growth curves for extremely preterm infants, including those of borderline viability, in Spain. A sexual dimorphism is evident for all of the studied parameters, starting at early gestation. Conclusions: These new gender-specific and population-based data could be useful for the improvement of growth assessments of extremely preterm infants in our country, for the development of epidemiological studies, for the evaluation of temporal trends, and for clinical or public health interventions seeking to optimize fetal growth (AU)


Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Lactente , Pré-Escolar , Criança , Crescimento , Recém-Nascido Prematuro/crescimento & desenvolvimento , /crescimento & desenvolvimento , Pesos e Medidas Corporais/estatística & dados numéricos , Valores de Referência , Cefalometria , Desenvolvimento Infantil , Espanha , Seguimentos
10.
Chaos ; 24(2): 024404, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24985458

RESUMO

Many sleep centres try to perform a reduced portable test in order to decrease the number of overnight polysomnographies that are expensive, time-consuming, and disturbing. With some limitations, heart rate variability (HRV) has been useful in this task. The aim of this investigation was to evaluate if inclusion of symbolic dynamics variables to a logistic regression model integrating clinical and physical variables, can improve the detection of subjects for further polysomnographies. To our knowledge, this is the first contribution that innovates in that strategy. A group of 133 patients has been referred to the sleep center for suspected sleep apnea. Clinical assessment of the patients consisted of a sleep related questionnaire and a physical examination. The clinical variables related to apnea and selected in the statistical model were age (p < 10(-3)), neck circumference (p < 10(-3)), score on a questionnaire scale intended to quantify daytime sleepiness (p < 10(-3)), and intensity of snoring (p < 10(-3)). The validation of this model demonstrated an increase in classification performance when a variable based on non-linear dynamics of HRV (p < 0.01) was used additionally to the other variables. For diagnostic rule based only on clinical and physical variables, the corresponding area under the receiver operating characteristic (ROC) curve was 0.907 (95% confidence interval (CI) = 0.848, 0.967), (sensitivity 87.10% and specificity 80%). For the model including the average of a symbolic dynamic variable, the area under the ROC curve was increased to 0.941 (95% = 0.897, 0.985), (sensitivity 88.71% and specificity 82.86%). In conclusion, symbolic dynamics, coupled with significant clinical and physical variables can help to prioritize polysomnographies in patients with a high probability of apnea. In addition, the processing of the HRV is a well established low cost and robust technique.


Assuntos
Frequência Cardíaca/fisiologia , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/fisiopatologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Intervalos de Confiança , Bases de Dados como Assunto , Eletrocardiografia , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Dinâmica não Linear , Curva ROC , Apneia Obstrutiva do Sono/diagnóstico por imagem , Inquéritos e Questionários , Ultrassonografia , Adulto Jovem
11.
An Pediatr (Barc) ; 81(2): 107-14, 2014 Aug.
Artigo em Espanhol | MEDLINE | ID: mdl-24113120

RESUMO

INTRODUCTION: Most anthropometric reference data for extremely preterm infants used in Spain are outdated and based on non-Spanish populations, or are derived from small hospital-based samples that failed to include neonates of borderline viability. OBJECTIVES: To develop gender-specific, population-based curves for birth weight, length, and head circumference in extremely preterm Caucasian infants, using a large contemporary sample size of Spanish singletons. PATIENTS AND METHODS: Anthropometric data from neonates ≤ 28 weeks of gestational age were collected between January 2002 and December 2010 using the Spanish database SEN1500. Gestational age was estimated according to obstetric data (early pregnancy ultrasound). The data were analyzed with the SPSS.20 package, and centile tables were created for males and females using the Cole and Green LMS method. RESULTS: This study presents the first population-based growth curves for extremely preterm infants, including those of borderline viability, in Spain. A sexual dimorphism is evident for all of the studied parameters, starting at early gestation. CONCLUSIONS: These new gender-specific and population-based data could be useful for the improvement of growth assessments of extremely preterm infants in our country, for the development of epidemiological studies, for the evaluation of temporal trends, and for clinical or public health interventions seeking to optimize fetal growth.


Assuntos
Gráficos de Crescimento , Lactente Extremamente Prematuro , Peso ao Nascer , Estatura , Cefalometria , Estudos Transversais , Feminino , Idade Gestacional , Humanos , Recém-Nascido , Masculino , Espanha
12.
Nutr Hosp ; 24(5): 596-606, 2009.
Artigo em Espanhol | MEDLINE | ID: mdl-19893871

RESUMO

OBJECTIVE: To quantify by means of the so-called "Healthy lifestyle pyramid" and after two educational interventions, the changes in food intake, daily activities, and hygiene and health habits in the short and long terms in a cohort of healthy children. MATERIALS AND METHOD: prospective longitudinal study with baseline assessment of dietary and lifestyle habits, and two assessments after two educational interventions. RESULTS: 52 children participated, mean age 7.9 years, 15.4% of them being obese. There was a statistically significant reduction in whole milk intake in both the short and long term. There was a significant decrease in the short term in the intake of processed cold meat and an increase in fruit intake. There was a significant reduction in sweets intake in the short term. There was a statistically significant change in hand washing in the short and long terms, as well as in beach bathing after eating. There also was a significant change in achieving an appropriate posture and not bathing too far away, both in the long run. Finally, there was a significant change in the short term in not using inappropriate sports playing fields. The frequency at which they practise sports in the long term was significantly increased as well as the number of weekly sports, in the short term. CONCLUSIONS: After two educational interventions, the children did significant modifications of their health habits in the short term or the long term, which contributes to modify the risk factors for disease in the adulthood.


Assuntos
Ingestão de Alimentos , Comportamento Alimentar , Educação em Saúde , Higiene , Atividade Motora , Criança , Feminino , Humanos , Masculino , Estudos Prospectivos , Inquéritos e Questionários
13.
Nutr. hosp ; 24(5): 596-606, sept.-oct. 2009. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-76621

RESUMO

Objetivo: Cuantificar tras dos intervenciones educacionales, con la denominada ‘Pirámide de estilo de vida saludable’, los cambios en ingesta, actividades diarias y hábitos de higiene y salud, a corto y largo plazo, en una cohorte de niños sanos. Material y métodos: Es un estudio longitudinal prospectivo con una evaluación basal de hábitos dietéticos y de vida, y dos evaluaciones posteriores tras las dos intervenciones educacionales. Resultados: Participaron 52 niños, con una media de 7,9 años y el 15,4% eran obesos. Hubo una reducción estadísticamente significativa en la ingesta de leche entera, tanto a corto como a largo plazo. Fue significativo a corto plazo la reducción en la ingesta de embutidos y un aumento de frutas. Hubo una reducción significativa en ingesta de dulces, a corto plazo. Hubo significación estadística en lavado de manos, a corto y a largo plazo, al igual que el baño en la playa tras comer. También lo hubo en lograr una postura adecuada y no nadar muy adentro, ambos a largo plazo; y por último a corto plazo, en no utilizar campos de deporte inadecuados. La frecuencia con que practican deportes, a largo plazo, tuvo un incremento significativo y también lo hubo en el número de ejercicios semanales, a corto plazo. Conclusiones: Los niños hicieron tras dos intervenciones educacionales modificaciones significativas de sus hábitos de salud a corto, o largo plazo lo que contribuye a modificar factores de riesgo de enfermedad en la vida adulta (AU)


Objective: To quantify by means of the so-called ‘Healthy lifestyle pyramid’ and after two educational interventions, the changes in food intake, daily activities, and hygiene and health habits in the short and long terms in a cohort of healthy children. Materials and method: prospective longitudinal study with baseline assessment of dietary and lifestyle habits, and two assessments after two educational interventions. Results: 52 children participated, mean age 7.9 years, 15.4% of them being obese. There was a statistically significant reduction in whole milk intake in both the short and long term. There was a significant decrease in the short term in the intake of processed cold meat and an increase in fruit intake. There was a significant reduction in sweets intake in the short term. There was a statistically significant change in hand washing in the short and long terms, as well as in beach bathing after eating. There also was a significant change in achieving an appropriate posture and not bathing too far away, both in the long run. Finally, there was a significant change in the short term in not using inappropriate sports playing fields. The frequency at which they practise sports in the long term was significantly increased as well as the number of weekly sports, in the short term. Conclusions: After two educational interventions, the children did significant modifications of their health habits in the short term or the long term, which contributes to modify the risk factors for disease in the adulthood (AU)


Assuntos
Humanos , Masculino , Feminino , Criança , Ingestão de Alimentos , Comportamento Alimentar , Educação em Saúde , Higiene , Atividade Motora , Estudos Prospectivos , Inquéritos e Questionários
14.
Rev Clin Esp ; 207(9): 464-8, 2007 Oct.
Artigo em Espanhol | MEDLINE | ID: mdl-17915170

RESUMO

BACKGROUND: Fractures are the clinical complication of osteoporosis. There are no previous studies that describe the prevalence of vertebral fractures (VF) in patients admitted into a hospital due to a hip fracture (HF). OBJECTIVE: To study the prevalence of vertebral fractures in elderly women in the moment of their admission to the hospital due to a hip fracture. METHOD: This is a cooperative, multicentric, case-control study, performed in 21 different hospitals of Spain by the Working Group on Osteoporosis of the Spanish Society of Internal Medicine. A total of 143 elderly women with hip fractures comprised the case group. The control group consists of 138 elderly women admitted into other wards of the hospital due to other diseases with no relationship with osteoporosis. A questionnaire was administered and a lateral thoracic and lumbar X-ray was performed to assess vertebral fractures applying Genant's criteria. RESULTS: The mean age of the patients with HF was 79.8 +/- 6.9 years and the mean age of the controls was 77.7 +/- 8.9 years. Patients suffering from HF had less weight than controls (BMI: 25.9 +/- 4.4 g/m2 vs 27.7 +/- 5.2 kg/m2, p = 0.002). Prevalence of VF was 62.6% in patients with HF, and 50% in controls (p = 0.039). CONCLUSIONS: Elderly women admitted to a hospital due to hip fracture have a very high prevalence of previously undiagnosed VF. Indeed, elderly women admitted into the hospital because of other diseases also have a high prevalence of VF. These facts must be taken into account due to the morbidity and mortality of VF, that increases the HF morbidity and mortality.


Assuntos
Fraturas do Quadril/complicações , Fraturas da Coluna Vertebral/complicações , Fraturas da Coluna Vertebral/epidemiologia , Idoso , Estudos de Casos e Controles , Feminino , Humanos , Prevalência
15.
Rev. clín. esp. (Ed. impr.) ; 207(9): 464-468, oct. 2007. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-057755

RESUMO

Objetivo. Conocer cuál es la prevalencia de FV sin diagnosticar en mujeres ancianas que ingresan en un hospital al sufrir una FC. Método. Estudio cooperativo multicéntrico, de casos y controles, realizado por el grupo de trabajo en osteoporosis de la Sociedad Española de Medicina Interna, en 21 hospitales de toda España. Ciento cuarenta y tres mujeres con FC constituyeron los casos y 138 mujeres ingresadas en otros servicios del mismo hospital, por patología no relacionada con la osteoporosis, fueron los controles. Se les realizó un cuestionario y una radiografía lateral de columna torácica y lumbar. Para el diagnóstico de la FV se aplicaron los criterios de Genant. Resultados. La edad media de las pacientes con FC fue de 79,8 ± 6,9 años, y de las controles 77,7 ± 8,9 años. Las pacientes con FC eran más delgadas que las controles, siendo su índice de masa corporal (IMC) de 25,9 ± 4,4 kg/m2 frente a 27,7 ± 5,2 kg/m2, p = 0,002. En el 62,6% de las pacientes con FC se observó al menos una FV, mientras que en las controles la prevalencia observada fue del 50% (p = 0,039). Conclusiones. Las mujeres que ingresan en un hospital por una FC tienen una muy elevada prevalencia de FV no diagnosticadas, estadísticamente significativa, superior a la obtenida en las controles, ancianas que ingresan por patología aguda no relacionada con la osteoporosis, en las cuales la prevalencia de FV es también muy elevada. Este hecho debe tenerse en cuenta, dada la morbimortalidad de la FV que se añade a la propia de la FC (AU)


Background. Fractures are the clinical complication of osteoporosis. There are no previous studies that describe the prevalence of vertebral fractures (VF) in patients admitted into a hospital due to a hip fracture (HF). Objective. To study the prevalence of vertebral fractures in elderly women in the moment of their admission to the hospital due to a hip fracture. Method. This is a cooperative, multicentric, case-control study, performed in 21 different hospitals of Spain by the Working Group on Osteoporosis of the Spanish Society of Internal Medicine. A total of 143 elderly women with hip fractures comprised the case group. The control group consists of 138 elderly women admitted into other wards of the hospital due to other diseases with no relationship with osteoporosis. A questionnaire was administered and a lateral thoracic and lumbar X-ray was performed to assess vertebral fractures applying Genant's criteria. Results. The mean age of the patients with HF was 79.8 ± 6.9 years and the mean age of the controls was 77.7 ± 8.9 years. Patients suffering from HF had less weight than controls (BMI: 25.9 ± 4.4 g/m2 vs 27.7 ± 5.2 kg/m2, p = 0.002). Prevalence of VF was 62.6% in patients with HF, and 50% in controls (p = 0.039). Conclusions. Elderly women admitted to a hospital due to hip fracture have a very high prevalence of previously undiagnosed VF. Indeed, elderly women admitted into the hospital because of other diseases also have a high prevalence of VF. These facts must be taken into account due to the morbidity and mortality of VF, that increases the HF morbidity and mortality (AU)


Assuntos
Feminino , Idoso , Humanos , Osteoporose/complicações , Fraturas do Quadril/epidemiologia , Fraturas do Quadril/etiologia , Traumatismos da Coluna Vertebral/epidemiologia , Traumatismos da Coluna Vertebral/etiologia , Espanha/epidemiologia , Fatores de Risco , Prevalência
16.
Acta pediatr. esp ; 64(10): 486-489, nov. 2006. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-050009

RESUMO

Antecedentes: La evolución de los estudios cineantropométricos ha permitido determinar que para obtener la composición corporal de un sujeto sólo sea necesario estudiar los componentes graso y muscular. El presente estudio tiene por objetivo valorar la composición corporal en escolares canarios mediante cineantropometría e impedancia, y comparar ambas técnicas de medida. Métodos: Diseño: estudio transversal. Sujetos: escolares canarios de entre 6 y 16 años de edad residentes en Gran Canaria y Tenerife. Selección de la muestra: muestreo, aleatorio estratificado simple, a partir de una población infinita de niños entre 6 y 16 años de edad, con un nivel de significación del 95% y un margen de error del 5%, y de p=q=0,5. El tamaño de la muestra obtenido a justado en función del porcentaje esperado de pérdidas es de 549 alumnos. Tratamiento estadístico: paquete informático SPSS 11.0. Se considera significativo el valor de p>=0,5. Comparación de los sistemas de medida mediante un modelo de regresión no lineal (método de Marquardt). Resultados: Hemos estudiado a 563 escolares: 254 niños y 309 niñas. Los dos procedimientos tienden a coincidir asintóticamente. El coeficiente de determinación para el porcentajede grasa ( A2) es de 0,93 y paral a masal ibre de grasa el A2 es de 0,63. Conclusiones: El modelo de regresión no lineal aplicado a un programa informático permite estimar la composición corporal corregida mediante datos obtenidos por impedancia, método con buena reproducibilidad a diferencia de la cineantropometría


Background: Kinanthropometric studies affirm that, to assess an individual's body composition, it is only necessary to establish his or her fat and muscle components. The purpose of this study was to assess body composition among school children from the Canary Islands by means of kinanthropometry and impedance, and to compare the two measuringte chniques. Methods: Design: Cross-sectional study. Subjects: Canary Island school children between the ages of 6 and 16 living on Gran Canaria and Tenerife. Sample selection: Stratified simple random sampling, from an infinite population of children between the ages of 6 and 16, with a level of significance of 95% and amargin of error of 5%,assuming that p=q=0.5. The required sample size, after adjustment for expected losses, was 549 school children. Statistical treatment: SPSS 11.0 statistical analysis application. A p value less than or equal to 0.5 was considered significant. The measuring systems were compared by means of a nonlinear regression model (the Marquardtm ethod). Results: We assessed 563 school children: 254 boys and 309 girls. The two procedure stended to coincide asymptotically. The coefficient of determination (A2) was 0.93 for the percentage of body fat and 0.63 for tal-free body mass. Conclusion: The application of the nonlinear regression model to a software application enables the estimation of corrected body composition on the basis of data obtained by means of impedance, which, unlike kinanthropometry, is a method with good reproducibility


Assuntos
Humanos , Composição Corporal , Deficiências do Desenvolvimento/diagnóstico , Antropometria/métodos , Impedância Elétrica , Epidemiologia Descritiva , Tecido Adiposo
17.
Prev. tab ; 8(2): 55-60, abr.-jun. 2006. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-050254

RESUMO

Fundamento: El tabaquismo constituye el principal problema de salud pública en los adolescentes. El consumo de cigarrillos depende de muchos factores, como la edad, sexo, educación, raza y nivel socioeconómico, entre otros. Nos hemos propuesto estudiar la posible influencia de algunos de estos factores en la iniciación al consumo de tabaco entre los adolescentes de 12 a 18 años del municipio de Arucas, Gran Canaria, especialmente la posible relación entre el consumo de tabaco y el nivel de estudios de sus padres y el consumo del mismo entre sus familiares, profesores y amigos. Asimismo nos interesa conocer la actitud de los fumadores hacia el abandono de esta adicción. Método: Estudio descriptivo transversal, realizado en la totalidad de los alumnos de secundaria (desde 1º de la ESO hasta 1º de Bachiller, ambos inclusive) de los institutos públicos de Arucas, en el curso 2003-2004. El total de alumnos entrevistados fue de 1.276. Resultados: La prevalencia total de fumadores fue del 22,9%. Con la excepción del primer curso de la ESO, la prevalencia de tabaquismo es mayor entre las mujeres que los varones, llegando a alcanzar el 31,6% en las mujeres de 4º de la ESO. No obtuvimos asociación entre el consumo de tabaco y el nivel de estudios del padre ni de la madre. Por el contrario el tabaquismo se asoció al consumo de tabaco del padre, la madre, los hermanos, los profesores, los compañeros de clase y los amigos, presentando esta última la odds ratio más elevada. El 73,2% de los escolares fumadores se ha planteado dejar de fumar, de una u otra manera.Conclusiones: El consumo de tabaco entre los escolares de enseñanza secundaria de Arucas se asocia al consumo de tabaco en su entorno, principalmente de sus amigos. El nivel de estudios de los padres no parece influir en el tabaquismo. Casi el 75% de los escolares que fuman, habitual o esporádicamente, se han planteado dejar de fumar (AU)


Background: Tobacco consumption is the main public health problem between teenagers. The consumption of tobacco depends on many factors as age, gender, education, race and socio economical level and others. We have studied the posible influence of some of these factors in the initiation of tobacco consumption between teenagers aged 12 to18 years old who lived in Arucas, and specially studied the possible association between tobacco consumption and study levels of their parents and tobacco consumption between their parents, brothers and friends. Method: Cross-sectional descriptive study, performed on the totality of secondary students from the public institutes of Arucas, Gran Canaria, during the course 2003-4. The total of students included in the study was 1276. Results: Total prevalence of smokers was 22.9%. Prevalence of tobacco consumption is greater between women than men in secondary students of Arucas, with the exception of 1st course of ESO where the prevalence is similar in both genders. 31.4% of the women of 4th course of ESO smoke. We did not find statistical association between the consumption of tobacco and the study level of their parents, but in the other hand we found a strong association between tobacco consumption in their parents, brothers, teachers and mainly friends. 73.2% of the secondary students have been thinking about quitting smoking somehow. Conclusions: The consumption of tobacco between secondary students of Arucas is associated to tobacco consumption of their parents, brothers and mainly friends. The levels of the study of their parents are not associated to the consumption of tobacco. Almost 75% of the smokers have been thinking about quitting smoking (AU)


Assuntos
Masculino , Feminino , Adolescente , Humanos , Abandono do Uso de Tabaco/psicologia , Tabagismo/epidemiologia , Atitude Frente a Saúde , Estudantes/estatística & dados numéricos , Epidemiologia Descritiva , Comportamento do Adolescente
18.
An Med Interna ; 22(10): 469-72, 2005 Oct.
Artigo em Espanhol | MEDLINE | ID: mdl-16351477

RESUMO

BACKGROUND: Vitamin supplements and minerals consumption (SPM) is increasing in occidental societies due to the growing concern about health by the population. OBJECTIVES: To have a initial approaching to the to SPM consumption in the Province of Las Palmas through 2000 and 2001. To identify SPM proportions that are dispensed as pharmaceutical specialities and those who are sold as parapharmacy products. Finally, to describe the evolution of this consumption throughout a year. METHOD: The information was obtained through the list of the whole pharmaceutical specialities and parapharmacy products through 2000 and 2001 who have at least a vitamin in its composition and/or a mineral. RESULTS: Usually, 297 pharmaceutical specialities and 216 parapharmacy products are currently being sold. Pharmaceutical specialities comprised 65.6% of the whole products sold and within them, vitamins were the most dispensed (41.5%). Regarding parapharmacy products, vitamins and minerals compounds were the products more sold (34.6%). Comparing to 2000, during 2001 there was a statistically significant increase in the consumption of parapharmacy products, remaining without changes the use of pharmaceutical specialities. CONCLUSION: On the basis of sold XX SPM consumption seems to be due mainly by pharmaceutical specialities rather than parapharmacy products. Nevertheless through 2001 there was an increase only in the parapharmacy products.


Assuntos
Suplementos Nutricionais , Uso de Medicamentos , Oligoelementos , Vitaminas , Humanos , Espanha/epidemiologia
19.
An. med. interna (Madr., 1983) ; 22(10): 469-472, oct. 2005. tab
Artigo em Espanhol | IBECS | ID: ibc-041626

RESUMO

Fundamento: El consumo de suplementos polivitamínicos y minerales (SPM) está aumentado en las sociedades occidentales como consecuencia de la preocupación de la población por la salud. Objetivos: Tener una primera aproximación al consumo de SPM en la provincia de Las Palmas en los 2000 y 2001. Identificar las proporciones de SPM que son dispensados como especialidades farmacéuticas y los que lo hacen como productos de parafarmacia. Describir cual es la tendencia evolutiva en el consumo de estos SPM en el período de un año. Método: La información se obtuvo de los listados de ventas de todas las especialidades farmacéuticas y productos de parafarmacia de los años 2000 y 2001, que contienen en su composición al menos una vitaminay/o un mineral. Resultados: habitualmente se dispensan 297 especialidades farmacéuticas y 216 productos de parafarmacia. Las especialidades farmacéuticas constituyeron el 65,6% de las ventas y entre ellas, las vitaminas resultaron ser las más dispensadas (41,5%). En las especialidades de parafarmacia, las más vendidas fueron los compuestos de vitaminas y minerales (34,6%). Con respecto al año 2000, en el año 2001 se produjo un aumento estadísticamente significativo en el consumo de productos de parafarmacia, permaneciendo estable el de las especialidades farmacéuticas. Conclusión: en base a las ventas realizadas, en la provincia de Las Palmas el consumo de SPM parece realizarse mayoritariamente por medio de especialidades farmacéuticas y en menor grado mediante productos de parafarmacia. Sin embargo, en el período 2000-2001, se observó un incremento del consumo sólo en los productos de parafarmacia


Background: Vitamin supplements and minerals consumption (SPM) is increasing in occidental societies due to the growing concern abouthealth by the population. Objectives: To have a initial approaching to the to SPM consumption in the Province of Las Palmas through 2000 and 2001. To identify SPM proportions that are dispensed as pharmaceutical specialities and those who are sold as parapharmacy products. Finally, to describe the evolution of this consumption throughout a year. Method: The information was obtained through the list of the whole pharmaceutical specialities and parapharmacy products through 200 and 2001 who have at least a vitamin in its composition and/or a mineral. Results: Usually, 297 pharmaceutical specialities and 216 parapharmacy products are currently being sold. Pharmaceutical specialities comprised 65.6% of the whole products sold and within them, vitamins were the most dispensed (41.5%). Regarding parapharmacy products, vitamins and minerals compounds were the products more sold (34.6%). Comparing to 2000, during 2001 there was a statistically significant increase in the consumption of parapharmacy products, remaining without changes the use of pharmaceutical specialities. Conclusion: On the basis of sold XX SPM consumption seems to bedue mainly by pharmaceutical specialities rather than parapharmacy products. Nevertheless through 2001 there was an increase only in theparapharmacy products


Assuntos
Humanos , Suplementos Nutricionais , Uso de Medicamentos , Oligoelementos , Vitaminas , Espanha/epidemiologia
20.
Rev. esp. enferm. metab. óseas (Ed. impr.) ; 12(6): 109-116, nov. 2003. tab
Artigo em Espanhol | IBECS | ID: ibc-27994

RESUMO

Fundamento. No se conoce cuál es el efecto que produce la administración crónica de estrógenos en el metabolismo mineral óseo del varón. Por otra parte, en algunos estudios se ha informado que un determinado polimorfismo del receptor de la vitamina D podría condicionar una mayor densidad mineral ósea. Estos estudios a menudo han mostrado resultados contradictorios y la mayor parte de ellos se han efectuado en mujeres. Por todo ello hemos realizado este trabajo en un grupo de varones transexuales que habían recibido estrógenos durante un mínimo de tres años, con el fin de analizar si un determinado polimorfismo del receptor de la vitamina D condiciona en ellos diferencias en el metabolismo mineral óseo. Método. Estudio transversal de casos y controles. Hemos estudiado marcadores bioquímicos de remodelado óseo, la densidad mineral ósea, así como varias hormonas sexuales y calciotropas. Resultados. Comparados con los controles, los transexuales mostraron menores valores de testosterona libre en sangre y mayores valores de estradiol y de densidad mineral ósea, tanto en la columna lumbar como en la cadera. La bioquímica general, los marcadores bioquímicos de remodelado óseo y las hormonas calciotropas no mostraron diferencias estadísticamente significativas entre ambos grupos. El polimorfismo del receptor de la vitamina D no condicionó ninguna diferencia en estas variables, ni en los transexuales ni en los controles. Conclusiones. No hemos encontrado asociación alguna entre el fenotipo transexual y la distribución del polimorfismo del receptor de la vitamina D. La administración crónica de estrógenos en el varón produce un aumento en los niveles de estradiol sérico, y un incremento en la densidad mineral ósea tanto en la columna lumbar como en la cadera, que no guarda relación con la presencia de un determinado polimorfismo del receptor de la Vitamina D, a pesar de existir una marcada reducción en la concentración de testosterona libre (AU)


Assuntos
Adulto , Masculino , Pessoa de Meia-Idade , Humanos , Estrogênios/metabolismo , Densidade Óssea , Receptores de Calcitriol , Receptores de Calcitriol/metabolismo , Transexualidade/metabolismo , Estudos Transversais , Biomarcadores , Reprodutibilidade dos Testes
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