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1.
Rev Med Virol ; : e2304, 2021 Oct 13.
Artigo em Inglês | MEDLINE | ID: mdl-34643006

RESUMO

The data on the predictors and prognosis of acute liver injury (ALI) among patients in coronavirus disease 2019 (COVID-19) patients are limited. The aim of this study was to determine the prevalence, predictors and outcomes of ALI among patients with COVID-19. A systematic review was conducted up to 10 June 2021. The relevant papers were searched from PubMed, Embase, Cochrane and Web of Science, and the data were analysed using a Z test. A total of 1331 papers were identified and 16 papers consisting of 1254 COVID-19 with ALI and 4999 COVID-19 without ALI were analysed. The cumulative prevalence of ALI among patients with COVID-19 was 22.8%. Male and having low lymphocyte levels were more likely to be associated with ALI compared with female and having higher lymphocyte level, odds ratio (OR): 2.70; 95% confidence interval (CI): 2.03, 3.60 and mean difference (MD) -125; 95% CI: -207, -43, respectively. COVID-19 patients with ALI had higher risk of developing severe COVID-19 compared with those without ALI (OR: 3.61; 95% CI: 2.60, 5.02). Our findings may serve as the additional evaluation for the management of ALI in COVID-19 patients.

2.
J Nutr Sci ; 10: e70, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34527228

RESUMO

Nutrition and maternal behavior are critical factors in fetal development. Maternal water intake is necessary to regulate metabolism and may influence fetal growth. This study aims to determine the effect of dehydration during pregnancy on birth weight and length. This cohort-prospective study took place in the area of Kebon Jeruk District Health Centre. A total of 38 subjects of pregnant women in their second trimester were examined. Subject characteristics were collected through direct measurements and interviews. Urine and blood samples were collected at the sixth trimester (32-34 and 35-37 weeks) to determine hydration status. Nutritional status was collected through food recall, while birth weight and length were obtained from the anthropometric measurements 30 min after birth. From a total of 38 subjects, 20 were dehydrated, and 18 were well hydrated. There was a significant relationship between hydration status and water intake, birth weight and length, head circumference, and chest circumference. After being corrected to the level of water intake, the difference in birth weight and length between the two groups were 500⋅6 g and 0⋅4 cm, and 0⋅8 cm and 1⋅4 cm for the head circumference and chest circumference (P < 0⋅05). It is recommended for mothers to monitor their weight and ensure fluid intake of 3⋅0 l per day. Further research requires more subjects to observe the effects of chronic maternal dehydration on pregnancy output and a cohort study that monitors infant development in the first six months of life.

3.
Adv Physiol Educ ; 45(3): 563-567, 2021 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-34319192

RESUMO

The COVID-19 pandemic has caused changes in the school learning system. Face-to-face learning shifted to remote learning using multimedia approaches. Online learning created particular difficulties for Physical Education (PE) teachers. Previously, they had to be role models in the teaching of physical activity. A national virtual workshop was conducted to support those teachers as they shift to remote learning. The purpose of the workshop was to provide PE instruction through social media and develop online learning modules. The 3 days of activities consisted of 4 lectures and 6 workshops provided to 177 PE teachers from 32 provinces in Indonesia. Participants were informed about the COVID-19 pandemic, its impact on children, and healthy life during the pandemic. Online applications that were free of charge, easy to use, highly rated, and widely downloaded were also introduced to them. These multimedia applications could help teachers develop and deliver remote learning modules to their students. The workshop supported the teachers as they adapted to interactive distance learning. The workshop also successfully illustrates an innovative distance learning module delivered through multimedia.


Assuntos
COVID-19 , Educação à Distância , Criança , Humanos , Multimídia , Pandemias , Educação Física e Treinamento , SARS-CoV-2
4.
J Reprod Immunol ; 146: 103343, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34116485

RESUMO

OBJECTIVES: Chronic inflammation and pelvic adhesion play a critical role in endometriosis-related infertility. Research studies suggest that TGF-ß superfamily members, such as soluble endoglin (sEng), growth differentiation factor 15 (GDF-15) and tumor growth factor-beta (TGF-ß1) contribute to the regulation of inflammation, angiogenesis and cell adhesion. The objective of this study is to investigate the association between the concentrations of these TGF-ß-related members and the clinical parameters of infertile women with endometriosis. MATERIALS AND METHODS: Sixty-five infertile women who underwent laparoscopy were divided into two groups in this study: those who had endometriosis (n = 33) and control subjects with benign gynecologic disorders (n = 32). The levels of TGF-ß- related members in peritoneal fluid and serum were evaluated by the enzyme-linked immunosorbent assay (ELISA). Clinical and hematological parameters were documented and analyzed. RESULTS: Endometriosis cases had significantly higher levels of sEng, GDF-15 and TGF-ß1 in peritoneal fluid (p<0.0005) compared to control subjects, but not in serum. Moreover, serum GDF-15 level was significantly elevated in the late-stage endometriosis compared to the early-stage group. The levels of three TGF-ß related molecules in peritoneal fluid showed positive correlations with rASRM score. Blood neutrophil counts have correlation with the peritoneal sEng concentration. CONCLUSION: Our novel evidence on the elevated concentration of peritoneal sEng and GDF-15 in endometriosis, specifically in the late-stage, may indicate the essential role of TGF-ß-dependent signaling in endometriosis. Serum GDF-15 might serve as a candidate biomarker for endometriosis severity. Further studies are warranted to investigate the role and regulation of these molecules in endometriosis.

5.
Int J Surg Case Rep ; 82: 105847, 2021 Mar 29.
Artigo em Inglês | MEDLINE | ID: mdl-33838487

RESUMO

INTRODUCTION: Cervical elongation could lead to cervical elongation thus worsen the descent of uterine prolapse. In certain cases, this hypertrophic and hyperplastic mass could have fragile surface with some bleeding and necrotic, resembling cervical cancer. As case of cervical elongation due to cervical fibroid is quite rare, such cases are valuable to be reported. We present two cases of cervical fibroid with cervical elongation resembling cervical malignancy. PRESENTATION OF CASE: First case was A 59-year-old lady with intractable vaginal mass since one day before admission. Bleeding from the mass was positive. We found a bulky vaginal mass exceeding hymenal ring, 14 × 7 × 6 cm sized, with some necrotic and discharge, foul smelling, and some bleeding area. Ultrasound evaluation revealed a cervical fibroid with differential diagnosis cervical malignancy. The second case was Mrs 53-year-old with vaginal mass since last year. For the last 7 months the mass has been bigger and could not be inserted into vagina, with some bleeding. We found globular vaginal mass 12 × 9 × 6 cm exceeding hymenal ring, with some necrotic and reddish surface, foul smelling, discharge, and some blood. Ultrasound evaluation revealed cervical mass on anterior lip with elongated cervices. Both cases have been menopaused. As the clinical presentation resembling malignancy, we did biopsy. The biopsy results were no evidence of malignancy, then we did Manchester fothergill, and colporaphy as needed. DISCUSSION: Length between internal to external cervical ostium ≥ 5 cm correlated to cervical elongation. Growing cervical mass could drag the cervix, predisposing to cervical elongation and prolapse. Cervical fibroids protruded through vagina was usually pedunculated. But in our cases, the fibroids were not pedunculated but manifested as a bulky mass on the cervical tissue with some bleeding and necrotics, mimicking cervical malignancy. The most important initial management besides ultrasound evaluation was mass biopsy. CONCLUSION: In such cervical fibroids with cervical elongation resembling cervical malignancy, biopsy is compulsory to determine the diagnosis and to lead the management.

6.
J Physiol Sci ; 71(1): 3, 2021 Jan 19.
Artigo em Inglês | MEDLINE | ID: mdl-33461486

RESUMO

Ketogenic diets (KD) have become popular diet to lose weight. However, the effect of such diets on brain function has not yet been clarified. Thus, we aimed to study the effects of KD on the neurogenesis and apoptosis in the dentate gyrus by assessing the expression of Ki-67 and Caspase-3. Rats (n = 24) were divided into four groups: control (normal diet), ketogenic diet (KD), time-restricted diet (TRD), and the combination of high-fat and time-restricted diet (CD) groups. The expression of Ki-67 in the TRD and CD groups was higher compared to others (P < 0.05), whereas no such difference was observed in the KD group. The number of Capase-3-positive cells decreased significantly in the TRD group (P < 0.05), but such decrease was not observed in the CD group. These results indicate that, although KD could be effective in reducing the body weight, possible adverse effect in the brain cannot be ignored.

7.
Vet World ; 13(10): 2126-2132, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-33281346

RESUMO

Background and Aim: The combination of vitrification techniques and in vitro maturation can reduce oocyte competence. Mitogen-activated protein kinase and maturation-promoting factor are significant in oocyte meiotic maturation regulation. This study aimed to analyze vitrification's effect, after warming followed by in vitro maturation, on the expressions of protein 38 (p38), cyclin-dependent kinase 1 (CDK1), and cyclin B and oocyte maturation level. Materials and Methods: Immature goat oocytes were soaked in vitrification and warming solutions. The procedure was followed by in vitro maturation and in vitro maturation without post-warming vitrification as a control. These oocytes, along with their cumulus, were vitrified using hemistraw in liquid nitrogen. Oocyte maturation was carried out in a maturation medium that was added with 10 µg/mL of FSH, 10 µg/mL of LH, and 1 µg/mL E2 for 22 h. The expressions of p38, CDK1, and cyclin B were observed using immunocytochemical methods, which were assessed semiquantitatively according to the modified Remmele method. The oocyte maturation level was observed using the aceto-orcein staining method based on the achievement of chromosomes up to the metaphase II stage and/or the formation of the polar body I. Results: p38 expression in vitrified oocytes after warming, followed by in vitro maturation, increased insignificantly (p≥0.05), with the acquisition of 3.91±2.69 and 2.69±0.50 in the control oocytes. CDK1 expression in vitrified oocytes decreased significantly (p≤0.05) after warming, followed by in vitro maturation, with the acquisition of 2.73±1.24 and 7.27±4.39 in the control oocytes. Cyclin B expression in vitrified oocytes decreased insignificantly (p≥0.05) after warming, followed by in vitro maturation, with the acquisition of 3.09±1.4 and 4.18±2.61 in the control oocytes. The proportion of vitrified oocyte maturation levels after warming, followed by in vitro maturation, decreased significantly (p≤0.05), with the acquisition of 45.45% and 77.27% in the control oocytes. Conclusion: This study concluded that vitrification after warming resulted in an insignificant increase in p38 expression, a significant decrease in CDK1 expression, an insignificant decrease in cyclin B expression, and a significant reduction in oocyte maturation levels.

8.
Am J Reprod Immunol ; 84(4): e13296, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32593225

RESUMO

PROBLEM: Soluble immune checkpoint molecules constitute the emerging novel mediators in immune regulation. Their role in the pathogenesis of endometriosis has not been fully addressed. In this study, we aimed to investigate the relationship between the clinical manifestation of endometriosis-associated infertility and the level of four soluble immune checkpoints: sCTLA4, sHLA-G, sPD-1, and sPD-L1. METHOD OF STUDY: The soluble immune checkpoint concentrations in serum and peritoneal fluid from 88 patients who underwent laparoscopy were evaluated by the enzyme-linked immunosorbent assay (ELISA). Clinical and hematological parameters were documented and analyzed. RESULTS: Endometriosis cases were evident to have significantly higher levels of serum sPD-L1 and all four molecules in peritoneal fluid compared to non-endometriosis control. Contrary, no significant differences were found in the concentration of serum sCTLA-4, sHLA-G and, sPD-1 between endometriosis and control group. There were significant positive correlations between serum and peritoneal fluid concentrations of sCTLA-4, sPD-L1, and sHLA-G. Serum sPD-L1 could discriminate endometriosis-related infertility to other pathological control. At a cutoff of 14,61 pg/mL, serum sPD-L1 had a sensitivity of 77% and specificity of 83%. Moreover, sPD-L1 level showed positive correlations with pelvic adhesion score and myeloid cell count. CONCLUSION: The elevated level of sPD-L1 in serum and immune checkpoint molecules in the peritoneal fluid could represent the hallmark of immune regulation in endometriosis. Serum sPD-L1 could serve as a potential noninvasive endometriosis biomarker. Also, the immune compartment related to the local immune checkpoint molecules may be implicated in biological mechanisms underlying endometriosis-related infertility.

9.
Enferm Clin ; 30 Suppl 3: 118-121, 2020 03.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-32331732

RESUMO

OBJECTIVE: The purpose of this study is to clarify the concept of relapse in drug abuse. METHOD: Concept analysis was examined using the help of various literature obtained through internet databases published from 1998 to 2019. RESULTS: Identification of attributes, antecedent, and consequences of relapse causes the operational definition of the concept of relapse as the return state of the client consuming drugs or the re-emergence of symptoms such as before, so the client is not able to sustain its behavior change over time. CONCLUSIONS: This concept analysis is able to demonstrate that the concept of relapse is a self-management therapy that is made to prevent the relapse in the area of addiction behavior and focus on the important problems of help addicts change their behavior to help the developments that addicts have made in the process of treatment or self-change.


Assuntos
Transtornos Relacionados ao Uso de Substâncias , Doença Crônica , Humanos , Recidiva , Transtornos Relacionados ao Uso de Substâncias/terapia
10.
Enferm Clin ; 30 Suppl 2: 541-546, 2020 03.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-32204232

RESUMO

OBJECTIVE: To determine the relationship between early preterm birth (22-33 weeks) and late preterm birth (34-36 weeks) labor with sociodemographic characteristics in primiparous and multiparous mothers. METHODS: Design of observational analysis on 134 mothers after preterm postpartum in East Java using frequency analysis. The case samples were: primiparous and multiparous mothers after preterm postpartum recorded in medical records at 8 hospitals, namely Soewandhi hospital, Universitas Airlangga, Islam Jemur Sari hospital, Sidoarjo hospital, Madiun Sogaten hospital, Jombang hospital, Ibnu Sina Gresik hospital, and Ngawi hospital. The instrument used in this study was a data collection sheet in the form of a questionnaire. RESULTS: Among 29 sociodemographic characteristic variables there were only 3 variables related to early preterm birth and late preterm birth with p<0.05, i.e. education was (OR 2.54, CI95%; 1.21-5.34, p<0.020) from 134 mothers including 66 mothers (49.3%) who have higher education and 68 mothers (50.7%) have low education, smoked mother was (OR 0.63, CI95%: 0.55-0.72, p<0.016) including 123 mothers (91.8%) who did not smoke and 11 mothers (8.2%) had smoking habits, and ANC visits during pregnancy (OR 0.37, CI95%: 0.16-0.89, p<0.043) of which there were 107 mothers (79.9%) who visited ANC>4 times and 27 mothers (20.1%) who visited ANC<4 times. CONCLUSIONS: There was a relationship between early preterm birth and late preterm birth with maternal sociodemographic characteristics, i.e. education, smoking, and the number of ANC visits during pregnancy. This can be used as the basis for subsequent studies in the prevention of sociodemographic disorders in primiparous and multiparous mothers.


Assuntos
Nascimento Prematuro , Feminino , Humanos , Recém-Nascido , Mães , Paridade , Gravidez , Nascimento Prematuro/epidemiologia , Fumar
11.
Enferm. clín. (Ed. impr.) ; 30(supl.3): 118-121, mar. 2020. tab
Artigo em Inglês | IBECS | ID: ibc-196125

RESUMO

OBJECTIVE: The purpose of this study is to clarify the concept of relapse in drug abuse. METHOD: Concept analysis was examined using the help of various literature obtained through internet databases published from 1998 to 2019. RESULTS: Identification of attributes, antecedent, and consequences of relapse causes the operational definition of the concept of relapse as the return state of the client consuming drugs or the re-emergence of symptoms such as before, so the client is not able to sustain its behavior change over time. CONCLUSIONS: This concept analysis is able to demonstrate that the concept of relapse is a self-management therapy that is made to prevent the relapse in the area of addiction behavior and focus on the important problems of help addicts change their behavior to help the developments that addicts have made in the process of treatment or self-change


No disponible


Assuntos
Humanos , Masculino , Adolescente , Adulto Jovem , Transtornos Relacionados ao Uso de Substâncias/prevenção & controle , Comportamento Aditivo/prevenção & controle , Prevenção Secundária , Recidiva , Terapia Comportamental/métodos
12.
Immunol Endocr Metab Agents Med Chem ; 18(1): 22-30, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-30369967

RESUMO

Background: Insulin resistance is a frequent metabolic disorder in Polycystic Ovary Syndrome (PCOS). Moringa oleifera has been shown to increase insulin expres-sion and decrease the degree of insulin in diabetes mellitus, therefore it is expected that Moringa oleifera could decrease insulin levels and increase folliculogenesis in PCOS. Objective: To prove the effect of Moringa oleifera leaf extract in various doses might decrease the insulin levels and increase folliculogenesis in female PCOS-insulin resistant rats. Methods: The three month old white rat of Wistar strain (Rattus norvegicus) 100-130 grams were divided into five groups (n=8) including normal control, PCOS-insulin re-sistance, PCOS-insulin resistance given metformin and PCOS-resistance insulin were giv-en Moringa oleifera leaf extract in two doses. Then, the PCOS model-insulin resistance by injection of testosterone propionate for 28 days. After 14 days treatment, we analysed insulin levels and folliculogenesis. Results: The PCOS control group showed a significant increase in insulin levels compared to the normal control group. The insulin levels from group treatment with Moringa oleifera leaf extract of 250 mg/kgBW was significantly lower than the PCOS control group. Ovarian histology analysis found that the number and diameter of follicle of PCOS control group showed a significant decrease compared to normal control group. In addition, the treatment with metformin and leaf Moringa oleifera dose 250 mg/kgBW and 500 mg/kgBW showed significant increase of folliculogenesis compared to PCOS control group. Conclusions: Moringa oleifera could lowering the blood insulin levels, subsequently decreasing the androgen thus allowed the increasing of folliculogenesis in PCOS.

13.
Asia Pac J Clin Nutr ; 26(Suppl 1): S26-S30, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28625033

RESUMO

BACKGROUND AND OBJECTIVES: During pregnancy, the body exhibits dynamic changes in fluid composition. More than 50%of women experience nausea and vomiting during the first trimester. Studies of hydration status in pregnant women are limited, and not in tropical countries, like in Indonesia. The objective of this study was to investigate the hydration status and appropriate biomarkers for determination of hydration status in pregnant women in West Jakarta. METHODS AND STUDY DESIGN: This study was cross-sectional. A total of 35 pregnant women aged (19-35 years) at the early second trimester of pregnancy was recruited. Urine osmolality, urine specific gravity, and serum osmolality were used to determine hydration status. Subjects then were divided into a hydration group (HG) and a dehydration group (DG). We used independent t tests, chi-square and Spearman rank correlation coefficient to analyse the data. RESULTS: The population was comparably divided between dehydration and hydration groups (57.1% and 42.9%, respectively). The proportions by age, parity, gestational age, height, weight, upper arm circumference, waist circumference, pelvic circumference, body temperature, blood pressure, and fundal height did not differ between groups (p>=0.05). There was a relationship between urine colour and hydration status (p<0.05). Differences in hydration biomarker status (urine osmolality and urine specific gravity) were noted between the groups (p<0.05). CONCLUSIONS: Dehydration may be common during pregnancy in tropical Indonesia and can be confirmed by the hydration biomarkers of urinary specific gravity and osmolality. Fluid balance is necessary to prevent health problems and intrauterine growth restriction in pregnant women.


Assuntos
Desidratação/diagnóstico , Água/metabolismo , Adulto , Estudos Transversais , Ingestão de Líquidos , Feminino , Nível de Saúde , Humanos , Indonésia , Gravidez , Equilíbrio Hidroeletrolítico , Adulto Jovem
14.
Acta Med Indones ; 46(3): 175-82, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25348179

RESUMO

AIM: to describe the profile of urinary infection (UI) and to analyze its risk factors and impacts. METHODS: subjects were enrolled consecutively from pediatric, urology, obstetrics and gynecology, and geriatric outpatient clinics at six teaching hospitals in various regions of Indonesia. Those with urinary tract infection and diabetes mellitus were excluded. The UI questionnaire was adapted from the 3 Incontinence Questions (3IQ). Written informed consent was obtained prior to the interview. RESULTS: about 2765 completed questionnaires were obtained. The overall UI prevalence was 13.0%, which consisted of prevalence of stress UI (4.0%), urgency UI/wet OAB (4.1%), dry OAB (1.6%), mixed UI (1.6%), overflow UI (0.4%), enuresis (0.4%), other UI (0.7%). The prevalence of UI was significantly higher (p<0.001) in geriatric population (22.2%) compared to the adult (12.0%), and pediatric population (6.8%). There was no prevalence difference (p>0.05) between male and female subjects. Enuresis and urgency UI/wet OAB were the most common UI in pediatric population. The prevalence was 2.3% and 2.1% respectively. Urgency UI and stress UI were the two most common type in adult and geriatric population. Both have an equal prevalence of 4.6%. The multivariate analysis showed that the prevalence of UI increased with LUTS (PR 4.22, 95%CI 2.98-5.97), chronic cough (PR 2.08, 95% CI 1.32-3.28), and fecal incontinence (PR 1.85, 95% CI 1.03-3.32). We found that UI impaired family life (25.3%), sexual relationship (13.6%), and job/school performance (23.7%). Frequent toilet use and reducing fluid intake were the two most common behavior changes. CONCLUSION: the prevalence of UI in Indonesia is nearly similar to other Asian countries. It increases with age and is not affected by gender. LUTS, chronic cough, and fecal incontinence may have significant effects on the prevalence. UI seems to impact daily life and behavior.


Assuntos
Incontinência Urinária/epidemiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Estudos Transversais , Feminino , Inquéritos Epidemiológicos , Humanos , Indonésia/epidemiologia , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Prevalência , Fatores de Risco , Inquéritos e Questionários , Incontinência Urinária/etiologia , Adulto Jovem
15.
Acta Med Indones ; 44(3): 214-21, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-22983076

RESUMO

AIM: to evaluate the test-retest reliability of the Indonesian version of OABSS and its correlation with other validated assessment tools for OAB. METHODS: eligible patients aged 18 years with established OAB were instructed to complete 3-day micturition diaries and the OABSS, International Prostate Symptom Score (IPSS) and Patient Perception of Bladder Condition (PPBC) on two separate visits: Week 0 and Week 2. Test-retest reliability was examined using the internal correlation coefficient (ICC) and weighted Kappa coefficients between first and second applications of the OABSS. Pearson or Spearman correlation coefficients were calculated to test the correlation of OABSS with IPSS, IPSS Quality of Life (QOL) item, PPBC and clinical variables of the 3-day voiding diary. RESULTS: ICC for the OABSS total score was 0.83. The weighted Kappa coefficients of individual scores in OABSS were 0.55-0.66. In the first and second applications of OABSS, the Pearson correlation coefficients were 0.46-0.56 and 0.36-0.53 between OABSS and three clinical variables of the 3-day voiding diary (frequencies of micturition, urgency and urge incontinence). At Visit 1, the Spearman correlation coefficients were 0.41 between OABSS and IPSS total score, 0.47 between OABSS and IPSS QOL, and 0.34 between OABSS and PPBC. At Visit 2, the Spearman correlation coefficients were 0.45 between OABSS and IPSS total score, 0.55 between OABSS and IPSS QOL, and 0.44 between OABSS and PPBC. CONCLUSION: the Indonesian version of OABSS showed excellent test-retest reliability in Indonesian OAB patients. A satisfactory correlation with IPSS total and QOL scores, PPBC and several clinical variables of the 3-day voiding diary was obtained, particularly with urgency frequency.


Assuntos
Inquéritos e Questionários/normas , Bexiga Urinária Hiperativa/diagnóstico , Adulto , Feminino , Humanos , Indonésia , Masculino , Pessoa de Meia-Idade , Percepção , Qualidade de Vida , Reprodutibilidade dos Testes , Estatísticas não Paramétricas , Bexiga Urinária Hiperativa/fisiopatologia , Bexiga Urinária Hiperativa/psicologia
16.
Insects ; 2(4): 491-8, 2011 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-26467828

RESUMO

The utilization of pesticides often leaves residues which potentially pollute the environment. This journal issue has been encouraging some researchers to find an environmentally friendly insecticide by a cheaper wood preservative method. The International Standard for Phytosanitary Measures 15 (ISPM 15) [1] that is adopted in wood packaging protection in Europe is not suitable for tropical countries like Indonesia. Therefore, the treatment by Organo-Complex-based wood preservation, which consists of copper chromium combined with natural organic compounds, is proposed for effective treatment at a lower cost. The bioassay test was subjected to dry wood termite Cryptotermes cynocephalus Light. The result showed that wood materials treated by 10 ppm Organo-Complex formula gave good results which were indicated by the low consumption and the fast termination of the termites. The toxicity analysis of C-C organic compound solution is classified as grade IV (WHO, 2003) [2], or not harmful. Analysis of the residual content four weeks after the spraying treatment showed a significant reduction in the inorganic content (copper chromate complex), in the range of 35%, and in extracts of natural materials (natural extracts), above 80%.

17.
J Sci Food Agric ; 90(3): 456-61, 2010 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-20355068

RESUMO

BACKGROUND: Methane (CH(4)) produced during ruminal fermentation represents a loss of 10-11% of gross energy intake. The use of browse species containing tannin as feed supplement for ruminants tends to increase in order to reduce CH(4) production. The present study was conducted to evaluate some tropical plants containing tannin as feed supplement (200 g kg(-1)) on in vitro CH(4) production and fermentation parameters. RESULTS: The crude protein (CP) content ranged from 87 to 390 g kg(-1) dry matter (DM) and was highest in Sesbania grandiflora (L.) Poiret. The neutral detergent fibre (NDF) concentration was highest in Pennisetum purpureum Schumach (725 g kg(-1) DM) and lowest in S. grandiflora (330 g kg(-1) DM). The ranking order of plants based on their total tannin content was Acacia mangium Willd. > Biophytum petersianum Klotzch > Jatropa curcas Linnaeus > Psidium guajava Linnaeus > Phaleria papuana > Persea americana Mill. > S. grandiflora. Methane gas production after 48 h of incubation was significantly (P < 0.05) lower with inclusion of A. mangium (PP + AM), B. petersianum (PP + BP), J. curcas (PP + JC) or P. guajava (PP + PG) as compared to control feed (PP). There was negative correlation between total tannin content and CH(4) production at 48 h of incubation (r = - 0.76). Concentration NH(3)-N was significantly (P < 0.01) higher with inclusion of S. glandiflora. Inclusion of P. guajava significantly (P < 0.05) suppressed protozoa population by 49.7% relative to control feed (PP). CONCLUSION: It was concluded that A. mangium, B. petersianum, J. curcas and P. guajava have potential to be used as a feed supplement to reduce CH(4) production in ruminants.


Assuntos
Fibras na Dieta/análise , Proteínas na Dieta/análise , Magnoliopsida/química , Metano/biossíntese , Rúmen/metabolismo , Taninos/análise , Ração Animal , Animais , Bovinos , Suplementos Nutricionais , Eucariotos , Fermentação , Rúmen/microbiologia , Clima Tropical
18.
Acta Med Indones ; 38(4): 189-92, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-17132881

RESUMO

AIM: to estimate the annual economic cost and quality of life related to OAB in Indonesia population by taking into account the direct cost, value of lost productivity and cost consequences associated with OAB. METHODS: cross sectional study was done in Geriatric Clinic and Urogynaecology Clinic in Dr. Cipto Mangunkusumo Hospital Jakarta from July 2005 to March 2006. Primary outcome of this study was annual cost of OAB, symptom and quality of life of OAB patients. Cost data related to personal routine care of OAB and transportation expenditures were obtained by using questionnaires modified from Dowell Bryant incontinence cost index validated questioner. Data related to quality of life were obtained by OAB-q questioner. Subjects included 30 male and female OAB patients aged 18-100 years. RESULTS: most of patients were female (96.7%). Median of age was 62.5 (30-93) years old, 56.7% patients were elderly (age more than 60 years). Median of total annual cost of OAB was Rp. 2,850,000,-. Median of total personal cost which consist of routine personal care costs and treatment costs were Rp. 2,850,000. Median of total cost which is expended by government for routine personal and treatment of OAB was Rp.2,500,000,- . Median score of symptom severity was 62.5. Quality of life score was divided into coping, concern, sleep, and social item. Median of coping score was 50.0, concern score was 43.1, sleep score was 50.8, and social score was 38.8. Median of total quality of life score was 44.7. Maximum score of symptom severity and quality of life should be 98.8. The higher the score, the more severe the symptom, but the better is the quality of life. CONCLUSION: total annual cost of OAB was Rp. 2,850,000, Quality of life of OAB patient was somewhat poor.


Assuntos
Custos de Cuidados de Saúde/estatística & dados numéricos , Bexiga Urinária Hiperativa/economia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Feminino , Humanos , Indonésia , Masculino , Pessoa de Meia-Idade , Qualidade de Vida , Estudos Retrospectivos , Inquéritos e Questionários , Bexiga Urinária Hiperativa/psicologia
19.
Fertil Steril ; 77(5): 1065-8, 2002 May.
Artigo em Inglês | MEDLINE | ID: mdl-12009370

RESUMO

OBJECTIVE: To determine the relative effectiveness of single vs. two transcervical monthly insertions of 252 mg of quinacrine for female sterilization. DESIGN: Controlled clinical study. SETTING: Family planning clinics of 6 academic centers. PATIENT(S): Sexually active reproductive-age women requesting sterilization. INTERVENTION(S): At each of six centers 70 and 30 women were randomly assigned to receive either one or two, respectively, monthly transcervical insertions to the fundus of 252 mg of quinacrine and 75 mg of diclofenac as pellets and they were followed for 1 year. MAIN OUTCOME MEASURE(S): Complications, side effects, and pregnancy failures. RESULT(S): There were no serious complications and side effects were transient and easily treated. There were 31 (7.4%) pregnancy failures in the single insertions group and 2 (1.1%) in the two insertions group, but with marked center variation. CONCLUSION(S): Quinacrine sterilization using two monthly insertions of 252 mg of quinacrine appears safe and reasonably effective.


Assuntos
Quinacrina/administração & dosagem , Esterilização Tubária , Adulto , Esquema de Medicação , Feminino , Humanos , Tábuas de Vida , Gravidez , Taxa de Gravidez , Quinacrina/efeitos adversos , Esterilização Tubária/métodos , Resultado do Tratamento
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