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1.
Arch Oral Biol ; 115: 104737, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32387743

RESUMO

OBJECTIVE: Different studies in the last decade have proposed that gene expression alterations that are independent of the DNA sequence may also play an important role in periapical disease. The present study aimed to assess the available evidence supporting a relationship between these alterations and apical periodontitis through a scoping review. DESIGN: Specific strategies were developed for different databases (MEDLINE via PubMed, Cochrane Library, Scopus, Web of Science, and Virtual Health Library) and a search performed by March 1st, 2019. The evidence sources were selected according to the eligibility criteria and underwent a critical appraisal of methodological quality. RESULTS: The initial search retrieved 212 references, with eight eligible articles after the removal of replicates and application of exclusion criteria. Five studies identified altered DNA methylation on inflammatory response genes (FOXP3, CXCL3, FADD, MMP2, MMP9, IFNG, IL4, IL12) on AP patients. Three others identified the alterations on the expression of several microRNAs (miR-29b, 106b, 125b, 143, 146a, 155, 198) during AP. No evidence was identified regarding mechanisms of histone methylation, or of epigenetic heritability or stability. CONCLUSIONS: There is available evidence for the involvement of different genetic regulatory mechanisms independent of changes in DNA sequence in the development or severity of apical periodontitis. However, due to methodological limitations, further research must be performed before novel therapies and diagnostic tools for AP may arise from these data.

2.
Dent Mater ; 35(2): 195-205, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30527507

RESUMO

OBJECTIVES: The increased demand for esthetics and minimally invasive tooth restorations resulted in a rapid development of adhesive dentistry. However, much controversy remains about the safe use and cytotoxic effects of different groups of dental adhesives. The present study performed a systematic review to identify the answer to the following question: are self-etch adhesives more cytotoxic than those employing the etch-and-rinse system? METHODS: This systematic review was performed in accordance with the PRISMA statement; a quality assessment for in vitro studies was conducted using the ToxRTool. Specific search strategies were developed and performed in the electronic databases MEDLINE via PubMed, Cochrane Library, Scopus, Web of Science, and LILACS/BBO. After removal of duplicated studies and application of the exclusion criteria, ten eligible articles were selected and submitted to a qualitative descriptive analysis comparing both groups of dental adhesives. Most in vitro test systems employed pulp cells or gingival fibroblasts. RESULTS: The methodologies presented great variability regarding the exposure to the test materials. Only four studies assessed the role of the degree of conversion of the materials in their toxicity, with conflicting results. SIGNIFICANCE: While the lack of methodological standardization among the studies still hinders the establishment of a relationship between type of dental adhesive and toxicity, studies employing dentin barrier systems indicate greater cytotoxicity for etch-and-rinse adhesives.


Assuntos
Colagem Dentária , Cimentos Dentários , Adesivos , Polpa Dentária , Dentina , Adesivos Dentinários , Teste de Materiais , Cimentos de Resina
3.
Braz Oral Res ; 31: e74, 2017 Sep 28.
Artigo em Inglês | MEDLINE | ID: mdl-29019548

RESUMO

The aim of this study was to undertake a qualitative and quantitative assessment of nanoscale alterations and wear on the surfaces of nickel-titanium (NiTi) endodontic instruments, before and after use, through a high-resolution, noncontact, three-dimensional optical profiler, and to verify the accuracy of the evaluation method. Cutting blade surfaces of two different brands of NiTi endodontic instruments, Reciproc R25 (n = 5) and WaveOne Primary (n = 5), were examined and compared before and after two uses in simulated root canals made in clear resin blocks. The analyses were performed on three-dimensional images which were obtained from surface areas measuring 211 × 211 µm, located 3 mm from their tips. The quantitative evaluation of the samples was conducted before and after the first and second usage, by the recordings of three amplitude parameters. The data were subjected to statistical analysis at a 5% level of significance. The results revealed statistically significant increases in the surface wear of both instruments groups after the second use. The presence of irregularities was found on the surface topography of all the instruments, before and after use. Regardless of the evaluation stage, most of the defects were observed in the WaveOne instruments. The three-dimensional technique was suitable and effective for the accurate investigation of the same surfaces of the instruments in different periods of time.


Assuntos
Endodontia/instrumentação , Níquel/química , Preparo de Canal Radicular/instrumentação , Titânio/química , Desenho de Equipamento , Humanos , Imageamento Tridimensional/métodos , Interferometria/métodos , Teste de Materiais , Valores de Referência , Reprodutibilidade dos Testes , Propriedades de Superfície , Fatores de Tempo
4.
Pesqui. bras. odontopediatria clín. integr ; 17(1): e2918, 13/01/2017. tab, graf
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-914287

RESUMO

Objective: To compare the bond strength of three-step and self-etch adhesive systems with and without prior acid etching on bonding of fiberglass posts in root canals. Material and Methods: Experiments were conducted on roots of five upper molars without curvature and sectioned in a cervical-apical direction. With the aid of a highspeed turbine and diamond tips, cylindrical cavities 7 mm in depth and 1.4 mm in diameter were made in the dentine. The roots of the same tooth were used, where the retainers were cemented, thus generating three groups: Group A: Adper Scotchbond Multipurpose Plus (SBMP) + Rely X ARC; Group B: Single Bond Universal (SBU-1) + Rely X ARC, with acid etching prior to adhesive insertion; Group C: Single Bond Universal (SBU-2) + Rely X ARC. The samples were stored in a bacteriological incubator at 37ºC with 100% humidity for 48h and were subsequently cross-sectioned to obtain 3 dentine discs 1mm in thickness. Forty-five specimens were subjected to the push-out test. Results: Through the analysis of variance and Tukey's test, it was found that SBMP showed, with statistical significance (p<0.05), highest bond strength when compared with the SBU-1 and SBU-2 systems. The observed difference in the discs was located in the cervical portion. Conclusion: The three-step adhesive system had higher bond strength with the substrate than the self-etching adhesive only in the disc in the cervical portion; further, statistically, the prior application of phosphoric acid in SBU-1 did not affect its bond strength significantly.


Assuntos
Condicionamento Ácido do Dente/métodos , Cimentos Dentários , Cimentos de Ionômeros de Vidro/química , Resistência à Tração , Análise de Variância , Brasil , Pinos Dentários
5.
Braz. oral res. (Online) ; 31: e74, 2017. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-952085

RESUMO

Abstract The aim of this study was to undertake a qualitative and quantitative assessment of nanoscale alterations and wear on the surfaces of nickel-titanium (NiTi) endodontic instruments, before and after use, through a high-resolution, noncontact, three-dimensional optical profiler, and to verify the accuracy of the evaluation method. Cutting blade surfaces of two different brands of NiTi endodontic instruments, Reciproc R25 (n = 5) and WaveOne Primary (n = 5), were examined and compared before and after two uses in simulated root canals made in clear resin blocks. The analyses were performed on three-dimensional images which were obtained from surface areas measuring 211 × 211 µm, located 3 mm from their tips. The quantitative evaluation of the samples was conducted before and after the first and second usage, by the recordings of three amplitude parameters. The data were subjected to statistical analysis at a 5% level of significance. The results revealed statistically significant increases in the surface wear of both instruments groups after the second use. The presence of irregularities was found on the surface topography of all the instruments, before and after use. Regardless of the evaluation stage, most of the defects were observed in the WaveOne instruments. The three-dimensional technique was suitable and effective for the accurate investigation of the same surfaces of the instruments in different periods of time.

6.
J Contemp Dent Pract ; 17(7): 536-41, 2016 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-27595718

RESUMO

AIM: The aim of this study was to evaluate the inflammatory response to MTA Fillapex, AH Plus, and Pulp Canal Sealer Extensive Work Time (EWT), in a murine bone defect grafting model. MATERIALS AND METHODS: Bilateral mandibular critical defects were produced in 45 Wistar rats with a trephine bur#2 and filled with the endodontic sealers. After 7, 14, and 28 days, the rats were euthanized and their jaws were histologically prepared. RESULTS: For the 7-day group, no statistical significance was observed among all studied groups (p > 0.05), and high levels of inflammatory infiltrate were detected. After 14 and 28 days, Pulp Canal Sealer EWT showed statistically lower inflammatory response in comparison to other sealers (p < 0.05) except for the control group (no sealers). CONCLUSION: Pulp Canal Sealer EWT presented the lowest levels of inflammatory response. The critical defect grafting model was an effective method to detect differences among differences on the biological response to endodontic sealers. CLINICAL SIGNIFICANCE: Knowing the biocompatibility of endodontics sealers that will be used in filling the root canal.


Assuntos
Materiais Restauradores do Canal Radicular/toxicidade , Compostos de Alumínio/toxicidade , Animais , Materiais Biocompatíveis/toxicidade , Compostos de Cálcio/toxicidade , Modelos Animais de Doenças , Combinação de Medicamentos , Resinas Epóxi/toxicidade , Mandíbula , Teste de Materiais , Óxidos/toxicidade , Ratos Wistar , Silicatos/toxicidade
7.
Iran Endod J ; 11(3): 188-91, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27471529

RESUMO

INTRODUCTION: The aim of this in vitro study was to evaluate the effect of 10% citric acid and 17% ethylenediaminetetraacetic acid (EDTA) irrigating solutions on the surface morphology of young and old root dentin by determining the number and diameter of dentinal tubules using scanning electron microscopy (SEM). METHODS AND MATERIALS: Fifty healthy human teeth collected from young (≤30 years) and old (≥60 years) individuals (n=25) were first prepared with a Largo bur #2 to produce smear layer on the root canal surface. Subsequently, the crowns and the root middle and apical thirds were sectioned and removed, and the cervical thirds were sectioned vertically in the buccal-lingual direction into two equal halves. The obtained samples were then immersed in 2.5% sodium hypochlorite for 30 min and randomly separated into two treatment groups for each age group. In each age group, ten samples were selected as controls and did not receive any type of treatment. The rest of the specimens were then rinsed, dried and treated for 4 min with 10% citric acid or 17% EDTA. The samples were then assessed with SEM regarding the number and diameter of dentinal tubules. All data were assessed using Student's t-test. The level of significance was set at 0.05. RESULTS: Regardless of the type of treatment, no significant differences were observed in the number of open tubules between the young and old root dentin (P>0.05). Nonetheless, the diameter of the tubules in the old root dentin was larger when 17% EDTA was used (P<0.05). Both, young and old root dentin did not differ with the 10% citric acid treatment (P>0.05). CONCLUSION: The results showed that 17% EDTA treatment induced a significant demineralization in old root dentin.

8.
Braz Oral Res ; 29: 1-7, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26486768

RESUMO

The aim of this study was to comparatively evaluate the bending resistance at 45º, the static and dynamic cyclic fatigue life, and the fracture type of the WaveOne (Dentsply Maillefer, Ballaigues, Switzerland) 25-08 and Reciproc (VDW, Munich, Germany) 25-08 instruments. A total of 60 nickel-titanium (NiTi) instruments (30 Reciproc and 30 WaveOne) from three different lots, each of which was 25 mm in length, were tested. The bending resistance was evaluated through the results of a cantilever-bending test conducted using a universal testing machine. Static and dynamic cyclic fatigue testing was conducted using a custom-made device. For the static and dynamic tests, a cast Ni-Cr-Mo-Ti alloy metal block with an artificial canal measuring 1.77 mm in diameter and 20.00 mm in total length was used. A scanning electron microscope was used to determine the type of fracture. Statistical analyses were performed on the results. The WaveOne instrument was less flexible than the Reciproc (p < 0.05). The Reciproc instrument showed better resistance in the static and dynamic cyclic fatigue tests (p < 0.05). The transverse cross-section and geometry of the instruments were important factors in their resistance to bending and cyclic fracture. Both of the instruments showed ductile-type fracture characteristics. It can be concluded that the Reciproc 25-08 instrument was more resistant to static and dynamic cyclic fatigue than the WaveOne 25-08 instrument, while the WaveOne 25-08 instrument was less flexible. Bending and resistance to cyclic fracture were influenced by the instruments' geometries and transverse cross-sections. Both of the instruments showed ductile-type fracture characteristics.


Assuntos
Instrumentos Odontológicos , Preparo de Canal Radicular/instrumentação , Ligas Dentárias , Análise do Estresse Dentário , Desenho de Equipamento , Teste de Materiais , Microscopia Eletrônica de Varredura , Estresse Mecânico
9.
Braz. oral res. (Online) ; 29(1): 1-7, 2015. tab, graf
Artigo em Inglês | LILACS | ID: lil-777181

RESUMO

The aim of this study was to comparatively evaluate the bending resistance at 45º, the static and dynamic cyclic fatigue life, and the fracture type of the WaveOne (Dentsply Maillefer, Ballaigues, Switzerland) 25-08 and Reciproc (VDW, Munich, Germany) 25-08 instruments. A total of 60 nickel-titanium (NiTi) instruments (30 Reciproc and 30 WaveOne) from three different lots, each of which was 25 mm in length, were tested. The bending resistance was evaluated through the results of a cantilever-bending test conducted using a universal testing machine. Static and dynamic cyclic fatigue testing was conducted using a custom-made device. For the static and dynamic tests, a cast Ni-Cr-Mo-Ti alloy metal block with an artificial canal measuring 1.77 mm in diameter and 20.00 mm in total length was used. A scanning electron microscope was used to determine the type of fracture. Statistical analyses were performed on the results. The WaveOne instrument was less flexible than the Reciproc (p < 0.05). The Reciproc instrument showed better resistance in the static and dynamic cyclic fatigue tests (p < 0.05). The transverse cross-section and geometry of the instruments were important factors in their resistance to bending and cyclic fracture. Both of the instruments showed ductile-type fracture characteristics. It can be concluded that the Reciproc 25-08 instrument was more resistant to static and dynamic cyclic fatigue than the WaveOne 25-08 instrument, while the WaveOne 25-08 instrument was less flexible. Bending and resistance to cyclic fracture were influenced by the instruments’ geometries and transverse cross-sections. Both of the instruments showed ductile-type fracture characteristics.


Assuntos
Instrumentos Odontológicos , Preparo de Canal Radicular/instrumentação , Ligas Dentárias , Análise do Estresse Dentário , Desenho de Equipamento , Teste de Materiais , Microscopia Eletrônica de Varredura , Estresse Mecânico
10.
Full dent. sci ; 6(21): 124-129, dez. 2014. tab
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-750192

RESUMO

O presente trabalho teve como objetivo levantar evidˆncias relacionadas …s doen‡as profissionais e/ou ocupacionais que os cirurgiães-dentistas estÆo vulner veis. Elaborou-se mediante a aplica‡Æo de m‚todos expl¡citos e sistematizados de busca, aprecia‡Æo cr¡tica e s¡ntese da informa‡Æo selecionada, uma revisÆo da literatura sobre o tema. Os trabalhos foram selecionados das bases de dados eletr“nicas (PubMed, Bireme, Nature, Scielo e Cochrane), sendo consultados no per¡odo de 1990 a 2013 sobre as seguintes tem ticas: “doen‡as ocupacionais na Odontologia”, “risco ocupacional odontol¢gico”, “Odontologia do trabalho”, “occupational disease Dentistry”, “occupational hazards”, “dentist”, “cirurgiÆo-dentista”, nos idiomas portuguˆs e inglˆs. Selecionaram-se 21 artigos de um total de 40 potencialmente relevantes, identificados nas pesquisas de base de dados, que reportaram sobre as diversas doen‡as ocupacionais. Concluiu-se que os cirurgiães-dentistas devem conscientizar-se dos riscos ocupacionais e que trabalhos educativos no sentido de preven‡Æo das doen‡as profissionais sÆo necess rios.


The present study aimed to collect evidence related to occupational diseases to which dental surgeons are exposed. A literature review on the subject was elaborated through the application of explicit and systematic search methods, critical appraisal, and synthesis of selected information. The studies were chosen from electronic databases (Pubmed, Bireme, Nature, SciELO and Cochrane), consulted in the period from 1990 to 2013 on the following topics: “occupational diseases in Dentistry”, “occupational hazards in Dentistry”, “dental work”, “occupational disease Dentistry”, “occupational hazards”, “dentist”, “dental surgeon”, in Portuguese and English. Twenty-one articles were selected from a total of 40 potentially relevant studies identified in the databases concerning various occupational diseases. It was concluded that dentists should become aware of occupational hazards and that further educational programs towards the prevention of occupational diseases are still necessary.


Assuntos
Odontologia do Trabalho , Doenças Profissionais , Saúde do Trabalhador , Riscos Ocupacionais
11.
J Endod ; 36(3): 515-9, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-20171374

RESUMO

INTRODUCTION: The biocompatibility of chelating agents and organic acids have been explained by a variety of methods, and suggestions for use have been based more on clinical observations and physicochemical properties than on biological aspects. The present study aimed to evaluate the inflammatory response of 17% EDTA, 17% EDTA-T, and 10% citric acid in bony defect created in rat jaws. METHODS: Mandibular through and through critical size defects were created bilaterally in 60 rats. Fibrinol (Baldacchi SA, São Paulo, Brazil), a cube-shaped compound of absorbable bovine fibrin foam and sodium chloride, was used as a carrier of the substances. One side had received Fibrinol (control), whereas the opposite side had received Fibrinol soaked with each substance on the 1st, on the 7th, on the 14th, and on the 28th day (n=5 for each day). Hemijaws were prepared for light microscopy, and samples were stained with hematoxylin and eosin. Digitized images were analyzed with a morphometric software (ImageJ; National Institute of Mental Health, Bethesda, MD). to obtain the number of inflammatory cells per area. Comparisons were performed by using the Kruskal-Wallis test (p=0.05). RESULTS: For all days, 10% citric acid and 17% EDTA-T showed, respectively, the lowest and highest number of inflammatory cells per area. All tested substances and controls showed the highest inflammatory cell response on the 14th day. CONCLUSION: Among the tested substances, 10% citric acid proved to be the less aggressive tested solution at 14 days. At 28 days, all solutions were similar, but EDTA-T kept showing the higher number of inflammatory cells.


Assuntos
Regeneração Óssea/efeitos dos fármacos , Ácido Cítrico/efeitos adversos , Ácido Edético/efeitos adversos , Inflamação/induzido quimicamente , Mandíbula/efeitos dos fármacos , Irrigantes do Canal Radicular/efeitos adversos , Animais , Bovinos , Quelantes/administração & dosagem , Quelantes/efeitos adversos , Ácido Cítrico/administração & dosagem , Ácido Cítrico/imunologia , Técnica de Descalcificação , Portadores de Fármacos/efeitos adversos , Combinação de Medicamentos , Ácido Edético/administração & dosagem , Ácido Edético/imunologia , Extravasamento de Materiais Terapêuticos e Diagnósticos/imunologia , Espuma de Fibrina/efeitos adversos , Teste de Materiais , Ratos , Ratos Wistar , Irrigantes do Canal Radicular/administração & dosagem , Dodecilsulfato de Sódio/administração & dosagem , Dodecilsulfato de Sódio/efeitos adversos , Tensoativos/administração & dosagem , Tensoativos/efeitos adversos
12.
Gerodontology ; 27(4): 278-82, 2010 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19572919

RESUMO

OBJECTIVE: This study was to evaluate the influence of medications on unstimulated and stimulated salivary flow in elderly men and women. BACKGROUND: Several diseases and conditions are associated with decreasing salivary flow. Medications can be risk factors for hyposalivation due to the effect particular drug categories. METHODS: Seventy-five elderly of both gender (sixty years old or over) from the Geriatric Dental Clinic at the Federal Fluminense University Dental School, were interviewed about their health status and chronic use of medication. After the interview, unstimulated and stimulated saliva were collected from each subject. The collection time was five minutes, and the flow rate was calculated as ml/min. RESULTS: The mean unstimulated salivary flow was 0.25 ml/min for women and 0.30 ml/min for men, while the mean for stimulated salivary flow was 1.23 ml/min for women and 1.31 ml/min for men, without both differences being non-significant (p > 0.05). The difference between the mean production of unstimulated and stimulated salivary flow was statistically significant, regardless of gender (p < 0.01). A significant reduction of stimulated salivary flow was observed with the usage of cardiovascular agents (p < 0.05). CONCLUSION: Drugs used in cardiovascular disease influence the flow of stimulated saliva.


Assuntos
Tratamento Farmacológico , Saliva/efeitos dos fármacos , Idoso , Idoso de 80 Anos ou mais , Ansiolíticos/uso terapêutico , Anticoagulantes/uso terapêutico , Antidepressivos/uso terapêutico , Anti-Hipertensivos/uso terapêutico , Fármacos Cardiovasculares/uso terapêutico , Feminino , Fármacos Gastrointestinais/uso terapêutico , Humanos , Hipoglicemiantes/uso terapêutico , Masculino , Pessoa de Meia-Idade , Farmacologia , Fatores de Risco , Saliva/metabolismo , Taxa Secretória/efeitos dos fármacos , Hormônios Tireóideos/uso terapêutico , Fatores de Tempo , Vitaminas/uso terapêutico
13.
J Appl Oral Sci ; 16(1): 24-9, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-19089285

RESUMO

This study compared, by scanning electron microscopy (SEM), the efficacy of three solvents on the removal of filling materials from dentinal tubules during endodontic retreatment. Forty human maxillary canines with straight canals were prepared according to a crown-down technique and enlarged to a#30 apical file size, before obturation with gutta-percha and a zinc-oxide-eugenol based sealer. The samples were stored for 3 months before being randomly assigned to four groups: chloroform (n=10), orange oil (n=10), eucalyptol (n=10) and control (n=10). Solvents were applied to a reservoir created on the coronal root third using Gates Glidden drills. The total time for retreatment using the solvents was 5 minutes per tooth. Following retreatment the roots were split longitudinally for SEM evaluation. SEM images were digitized, analyzed using Image ProPlus 4.5 software, and the number of dentinal tubules free of filling material from the middle and apical thirds was recorded. No significant difference was found among the solvent groups regarding the number of dentinal tubules free of root filling remnants in the middle and apical root thirds (p>0.05). However, the control group had fewer dentinal tubules free of filling material (p<0.05). Under the tested conditions, it may be concluded that there was no significant difference among the solvents used to obtain dentinal tubules free of filling material remnants.


Assuntos
Cavidade Pulpar/efeitos dos fármacos , Irrigantes do Canal Radicular/uso terapêutico , Preparo de Canal Radicular/métodos , Solventes/uso terapêutico , Clorofórmio/uso terapêutico , Dente Canino/ultraestrutura , Cicloexanóis/uso terapêutico , Cavidade Pulpar/ultraestrutura , Dentina/efeitos dos fármacos , Dentina/ultraestrutura , Eucaliptol , Eucalyptus , Guta-Percha/uso terapêutico , Humanos , Processamento de Imagem Assistida por Computador , Teste de Materiais , Microscopia Eletrônica de Varredura , Monoterpenos/uso terapêutico , Óleos Vegetais/uso terapêutico , Retratamento , Materiais Restauradores do Canal Radicular/uso terapêutico , Obturação do Canal Radicular , Fatores de Tempo , Ápice Dentário/efeitos dos fármacos , Ápice Dentário/ultraestrutura , Cimento de Óxido de Zinco e Eugenol/uso terapêutico
14.
J. appl. oral sci ; 16(1): 24-29, Jan.-Feb. 2008. ilus, tab
Artigo em Inglês | LILACS | ID: lil-472685

RESUMO

This study compared, by scanning electron microscopy (SEM), the efficacy of three solvents on the removal of filling materials from dentinal tubules during endodontic retreatment. Forty human maxillary canines with straight canals were prepared according to a crown-down technique and enlarged to a#30 apical file size, before obturation with gutta-percha and a zinc-oxide-eugenol based sealer. The samples were stored for 3 months before being randomly assigned to four groups: chloroform (n=10), orange oil (n=10), eucalyptol (n=10) and control (n=10). Solvents were applied to a reservoir created on the coronal root third using Gates Glidden drills. The total time for retreatment using the solvents was 5 minutes per tooth. Following retreatment the roots were split longitudinally for SEM evaluation. SEM images were digitized, analyzed using Image ProPlus 4.5 software, and the number of dentinal tubules free of filling material from the middle and apical thirds was recorded. No significant difference was found among the solvent groups regarding the number of dentinal tubules free of root filling remnants in the middle and apical root thirds (p>0.05). However, the control group had fewer dentinal tubules free of filling material (p<0.05). Under the tested conditions, it may be concluded that there was no significant difference among the solvents used to obtain dentinal tubules free of filling material remnants.


Assuntos
Humanos , Cavidade Pulpar/efeitos dos fármacos , Irrigantes do Canal Radicular/uso terapêutico , Preparo de Canal Radicular/métodos , Solventes/uso terapêutico , Clorofórmio/uso terapêutico , Dente Canino/ultraestrutura , Cicloexanóis/uso terapêutico , Cavidade Pulpar/ultraestrutura , Dentina/efeitos dos fármacos , Dentina/ultraestrutura , Eucalyptus , Guta-Percha/uso terapêutico , Processamento de Imagem Assistida por Computador , Teste de Materiais , Microscopia Eletrônica de Varredura , Monoterpenos/uso terapêutico , Óleos Vegetais/uso terapêutico , Retratamento , Obturação do Canal Radicular , Materiais Restauradores do Canal Radicular/uso terapêutico , Fatores de Tempo , Ápice Dentário/efeitos dos fármacos , Ápice Dentário/ultraestrutura , Cimento de Óxido de Zinco e Eugenol/uso terapêutico
15.
JBG J. bras. odonto ; 2(7): 101-106, out.-dez.2006.
Artigo em Português | BBO - Odontologia | ID: biblio-851862

RESUMO

O aumento no mundo da população idosa é uma realidade. Hoje em dia, cada vez mais pacientes idosos buscam tratamento odontológico. É importante para o profissional da Odontologia conhecer as mudanças fisiológicas e as doenças mais comuns que ocorrem com o envelhecimento. Prováveis reações adversas às drogas e toxicidades em função da polifarmácia a qual estes pacientes estão submetidos são também um fator determinante para evitar complicações durante o tratamento em Odontogeriatria


Assuntos
Dinâmica Populacional , Uso de Medicamentos , Odontologia Geriátrica , Envelhecimento , Assistência Odontológica para Idosos , Relações Dentista-Paciente , Tratamento Farmacológico , Conhecimento , Prática Profissional
16.
RPG rev. pos-grad ; 12(4): 430-436, out.-dez. 2005. tab, graf
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-556098

RESUMO

O presente estudo objetivou determinar os teores de cloro e oxigênio em ppm, quando empregado hipoclorito de sódio (NaOCl) nas concentrações de 0,5%; 1,0% e 5,0% associado com peróxido de hidrogênio (H2O2) 3%, ácido cítrico 10% e EDTA 17%. Avaliaram-se, também, as reações do creme Endo PTC com NaOCl 0,5% e 5%. A determinação do teor de cloro (Cl2) foi realizada no espectrofotômetro ultravioleta visível analógico pelo método alaranjado de metila. O teor de oxigênio (O2) foi analisado volumetricamente pelo método de Winkler. O tempo reacional para produzir cloro e oxigênio foi 3 minutos. Padronizou-se o volume em 10 ml para as soluções testadas. Para realizar a reação do creme Endo PTC, utilizou-se 0,2 g com 2 ml das soluções de NaOCl 0,5% e 5,0%, no mesmo período de tempo. Os resultados demonstraram que a produção de CL2 foi encontrada nas reações entre NaOCl com ácido cítrico (0,07; 0,11 e 0,15 ppm) e com EDTA (0,01; 0,05 e 0,08 ppm). A produção de O2 foi encontrada nas reações do NaOCl com H2O2 (0,03; 0,18 e 0,49 ppm). Na reação com Endo PTC e NaOCl a 0,5% e 5,0%, observou-se também a produção de O2 (0,08 e 0,43 ppm), porém o gás cloro Cl2 só foi constatado na reação com NaOCl 5,0% (0,06 ppm). Concluiu-se que formação de Cl2 foi maior quando NaOCl 5% reagiu com ácido cítrico. A maior formação de O2 foi encontrada na reação de NaOCl 5% com H2O2, assim como na reação do NaOCl 5% com Endo PTC.


Assuntos
Reações Químicas , Endodontia , Irrigantes do Canal Radicular , Peróxido de Hidrogênio , Oxigênio , Hipoclorito de Sódio
17.
Artigo em Inglês | MEDLINE | ID: mdl-15472668

RESUMO

OBJECTIVE: An in vitro study was conducted to evaluate the effect of EDTA-T, 17% EDTA, and 10% citric acid on the removal of smear layer from root canal dentin after final irrigation for 3, 10, and 15 min. STUDY DESIGN: Root canals of 90 extracted human canines were divided into 9 groups of 10 teeth; each group received a final irrigation with one of the irrigants for the established time intervals. After irrigation, the teeth were split and prepared for SEM analysis to determine the number of open dentinal tubules. RESULTS: There were statistically significant better results (P <.05) when irrigation with 10% citric acid for 3 min was compared to 10 and 15 min, and when irrigation with EDTA for 3 min was compared to 15 min. In all cases, irrigation for 3 min presented the greatest number of open dentinal tubules. There were no significant differences (P>.05) for the 3 time intervals of irrigation for EDTA-T, although there were a greater number of open tubules at 3 min. CONCLUSION: These 3 irrigants were effective at the shortest time tested and did not demonstrate an improved effect with an increase in time.


Assuntos
Ácido Cítrico/administração & dosagem , Dente Canino/efeitos dos fármacos , Ácido Edético/administração & dosagem , Humanos , Microscopia de Força Atômica , Camada de Esfregaço , Estatísticas não Paramétricas , Irrigação Terapêutica , Fatores de Tempo
18.
Rev. bras. odontol ; 60(5): 310-313, set.-out. 2003. tab, graf
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-404158

RESUMO

O presente trabalho verificou a necessidade do uso e da troca de próteses (parcial e total) de 103 pacientes com idade acima de 60 anos envolvidos no Programa Interdisciplinar de Geriatria e Gerontologia da UFF. No que diz respeito à necessidade de utilização de próteses tanto parciais como totais, verificou-se que, em relação aos homens, as mulheres tinham a menor probabilidade de permanecer sem os dentes (p<0,05). Entretanto, com relação à necessidade de troca das próteses, não foi observada diferença estatística entre os sexos. As alterações vasculares da cavidade bucal foram significativas nos pacientes com faixa etária maior


Assuntos
Humanos , Masculino , Feminino , Idoso , Prótese Total , Prótese Parcial , Índice CPO , Odontologia Geriátrica
19.
Artigo em Inglês | MEDLINE | ID: mdl-12582366

RESUMO

OBJECTIVE: An in vitro study was conducted to determine the efficacy of 17% EDTA plus 1.25% sodium lauryl ether sulfate (EDTA-T), 10% citric acid, and 17% EDTA with respect to Ca(++) extraction. STUDY DESIGN: The root canals of 90 extracted human canines were instrumented by using the step-back technique. The teeth were randomly divided into 9 groups of 10 teeth each according to the solution and time intervals involved (ie, 3, 10, and 15 minutes). The Ca(++) concentration of the solution was determined by using atomic absorption spectroscopy. RESULTS: At 3 minutes, there was no significant difference between Ca(++) extraction by 10% citric acid and 17% EDTA (P >.05). EDTA-T had the least efficacy for Ca(++) extraction (P <.05). At 10 minutes and 15 minutes, there were no significant differences between 10% citric acid and 17% EDTA or between EDTA-T and 17% EDTA (P >.05). However, 10% citric acid was significantly better than EDTA-T in terms of Ca(++) extraction (P <.05). CONCLUSION: Both 10% citric acid and 17% EDTA are good decalcifying agents when the step-back technique is used.


Assuntos
Quelantes/administração & dosagem , Ácido Cítrico/administração & dosagem , Ácido Edético/administração & dosagem , Preparo de Canal Radicular/métodos , Dente Canino , Técnica de Descalcificação , Dentina/efeitos dos fármacos , Humanos , Polietilenoglicóis/administração & dosagem , Camada de Esfregaço
20.
Rev. bras. odontol ; 59(6): 378-379, nov.-dez. 2002. tab
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-331299

RESUMO

Baseou-se verificar in vitro a capacidade de quelaçäo de íons de cálcio (Ca++) da dentina dos canais radiculares, quando do emprego de EDTA a 17 por cento e ácido cítrico a 10 por cento. A determinaçäo do teor de cálcio nas amostras foi feita pela espectrofotometria de absorçäo atômica. Os valores das leituras foram analisados estatisticamente tendo como nível crítico de significância 5 por cento. Considerando os intervalos de tempo de 3, 10 e 15 minutos versus substâncias, näo existiu diferença significativa entre o ácido cítrico a 10 por cento e EDTA a 17 por cento (p>0,05)


Assuntos
Ácido Cítrico/administração & dosagem , Ácido Edético/administração & dosagem , Terapia por Quelação , Dentina , Técnicas In Vitro , Dente Canino
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