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J Ethnopharmacol ; 233: 218-233, 2019 Apr 06.
Artigo em Inglês | MEDLINE | ID: mdl-30686574


ETHNOPHARMACOLOGICAL RELEVANCE: Ensete superbum (Roxb.) Cheesman. (Family: Musaceae), commonly known as "Wild Banana" is well recorded as popular ethnomedicine for medicinal and nutritional uses by different people and communities native to India, Ethiopia, Thailand, Myanmar and Vietnam. AIM OF THE REVIEW: Despite the wide ethnomedicinal and pharmacological studies on E. superbum, there are no concise elaborated article comprising reviews of published literature. So, herein we designed this review article to discuss the current ethnopharmacology, pharmacognosy, phytochemistry, pharmacology and intellectual property status of E. superbum. MATERIALS AND METHODS: Exhaustive literature searches were performed on E. superbum through various scientific and patent search engines such as Google Scholar, Scopus, PubMed, USPTO, Google patents, and Espacenet, using different keywords for screening of relevant information. RESULTS: E. superbum was recorded in different regions of the world for ailments such as dog bite, calculi, semen production, abortion, leucorrhoea, stomachache, immune response, pain, diabetes, psychosomatic, contraceptive, umbilical cord care, convulsions, pneumonia, cholera, labor and delivery pain, dehydration, appendicitis, chickenpox, measles, urinary problems, food poisoning, snake bites, diarrhoea, dysentery, jaundice, bone fracture, infections, fever, asthma, hiccups and leucoderma. Major bioactive phytochemicals such as triterpenoid esters, proanthocyanidin, pro-pelargonidin glucosides, pelargonidin, anigorufone, hydroxyanigorufone, ß-carboline alkaloids and fractions such as VIDR-2T, VIDR-2GC, VIDR-2GD were reported. Pharmacologically, E. superbum was found to be non-toxic (LD50 = 3235.9 mg/kg) and has been reported to possesses antiurolithiatic, antidiabetic, antifertility, anti-estrogenic, antiviral, cardiovascular and anti-inflammatory activities. CONCLUSIONS: E. superbum could be an excellent source of safe and effective medicinal and nutritional herbal remedies for human and animal consumption.

Musa , Fitoterapia , Animais , Humanos , Medicina Tradicional , Musa/química , Patentes como Assunto , Compostos Fitoquímicos/análise , Compostos Fitoquímicos/farmacologia , Compostos Fitoquímicos/uso terapêutico , Preparações de Plantas/química , Preparações de Plantas/farmacologia , Preparações de Plantas/uso terapêutico
J Chromatogr Sci ; 53(5): 816-23, 2015 May-Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25217706


In this study, we investigated a new, simple, sensitive, selective and precise high-performance thin-layer chromatography (HPTLC) fingerprint and quantitative estimation method for the analysis of ursolic acid, betulinic acid, stigmasterol and lupeol in Shankhpushpi botanicals. Linear ascending development was carried out in a twin trough glass chamber saturated with petroleum ether-ethyl acetate-toluene (7:2:1, v/v/v). The plate was dried, sprayed with anisaldehyde reagent and analyzed by CAMAG TLC scanner III at 580 nm. The system was found to give compact spots for ursolic acid (0.21), betulinic acid (0.29), stigmasterol (0.33) and lupeol (0.50). The relationship between the concentration of standard solutions and the peak response is linear within the concentration range of 100-600 ng/spot for ursolic acid, betulinic acid, stigmasterol and lupeol. The concentration of 134.2 and 146.1 mg of ursolic acid per gram of Clitorea ternatea (CT) and Canscora decussata (CD); 110.6 mg of betulinic acid per gram of EA; 92.75, 154.95, 31.947 and 39.21 mg of stigmasterol per gram of Evolvulus alsinoides (EA), Convolvulus pluricaulis (CP), CT and CD; 30.12 mg of lupeol per gram of CT were found. The proposed HPTLC method may use for routine quality testing and identification of Shankhpushpi botanicals.

Cromatografia em Camada Delgada/métodos , Triterpenos Pentacíclicos/análise , Extratos Vegetais/análise , Plantas Medicinais/química , Estigmasterol/análise , Triterpenos/análise , Índia , Triterpenos Pentacíclicos/isolamento & purificação , Extratos Vegetais/isolamento & purificação , Estigmasterol/isolamento & purificação , Triterpenos/isolamento & purificação
J Adv Pharm Technol Res ; 1(3): 311-9, 2010 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-22247863


Nymphaea stellata Willd. (Syn. Nymphaea nouchali Burman f.) (Nymphaeaceae) is an important and well-known medicinal plant, widely used in the Ayurveda and Siddha systems of medicines for the treatment of diabetes, inflammation, liver disorders, urinary disorders, menorrhagia, blenorrhagia, menstruation problem, as an aphrodisiac, and as a bitter tonic. There seems to be an agreement between the traditional use and experimental observations, such as, hepatoprotective, anti-inflammatory, and particularly antidiabetic activity. Nymphayol, a steroid isolated from the flowers has been scientifically proved to be responsible for the traditionally claimed antidiabetic activity; it reverses the damaged endocrine tissue and stimulates secretion of insulin in the ß-cells. However, taking into account the magnitude of its traditional uses, the studies conducted are still negligible. This review is an attempt to provide the pharmaceutical prospective of Nymphaea stellata.

Zhong Xi Yi Jie He Xue Bao ; 7(11): 1001-22, 2009 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-19912732


Shankhpushpi is an Ayurvedic drug used for its action on the central nervous system, especially for boosting memory and improving intellect. Quantum of information gained from Ayurvedic and other Sanskrit literature revealed the existence of four different plant species under the name of Shankhpushpi, which is used in various Ayurvedic prescriptions described in ancient texts, singly or in combination with other herbs. The sources comprise of entire herbs with following botanicals viz., Convulvulus pluricaulis Choisy. (Convulvulaceae), Evolvulus alsinoides Linn. (Convulvulaceae), Clitoria ternatea Linn. (Papilionaceae) and Canscora decussata Schult. (Gentianaceae). A review on the available scientific information in terms of pharmacognostical characteristics, chemical constituents, pharmacological activities, preclinical and clinical applications of controversial sources of Shankhpushpi is prepared with a view to review scientific work undertaken on Shankhpushpi. It may provide parameters of differentiation and permit appreciation of variability of drug action by use of different botanical sources.

Cognição/efeitos dos fármacos , Materia Medica/farmacologia , Medicina Ayurvédica , Memória/efeitos dos fármacos , Humanos , Materia Medica/química , Materia Medica/classificação , Farmacognosia