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ESC Heart Fail ; 7(2): 692-696, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31802644


Cardiac sarcoidosis is a chronic inflammatory disease with a large spectrum of symptoms that can mimic diseases such as dilated, hypertrophic, or arrhythmogenic cardiomyopathies. It can be asymptomatic but can also present with ventricular arrhythmias, conduction disease, and heart failure (HF) or even sudden cardiac death (SCD). We present here the case of a patient transplanted due to end-stage arrhythmogenic right ventricular cardiomyopathy (ARVC), fulfilling the task force criteria. A few years after successful heart transplantation (HTX), the patient developed similar symptoms and morphofunctional changes of the heart, which led to critical re-evaluation of his primary diagnosis.

Diagnosis (Berl) ; 3(4): 183-188, 2016 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-29536899


microRNAs are promising biomarkers for diverse cardiovascular diseases. While quantification of the small non-coding RNAs is routinely performed in the research laboratory, clinical-grade assessment of microRNAs in central laboratory environments or point-of-care testing is still in its infancy. In this review, we provide an overview on microRNAs as biomarkers for acute coronary syndromes and highlight promising technical approaches for microRNA-based assays systems.

Síndrome Coronariana Aguda/diagnóstico , Síndrome Coronariana Aguda/genética , MicroRNAs/genética , Síndrome Coronariana Aguda/sangue , Doença Aguda , Biomarcadores/sangue , Biomarcadores/metabolismo , Doenças Cardiovasculares/genética , Glicopeptídeos/sangue , Humanos , Imunoensaio/métodos , MicroRNAs/sangue , Infarto do Miocárdio/sangue , Testes Imediatos/estatística & dados numéricos , Valor Preditivo dos Testes , Prognóstico , Reação em Cadeia da Polimerase em Tempo Real/métodos , Infarto do Miocárdio com Supradesnível do Segmento ST/sangue , Infarto do Miocárdio com Supradesnível do Segmento ST/genética , Troponina T/sangue