Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 16 de 16
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Saudi J Kidney Dis Transpl ; 31(1): 271-275, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32129224

RESUMO

De novo renal allograft tumors were reported sporadically. Most of them were small, low-grade, and papillary renal cell carcinoma (RCC) type. A 46-year-old male presented with hematuria three decades after the first transplant. The patient had a history of three renal transplants. A tumor (12 cm × 13 cm) was diagnosed in the nonfunctioning first transplanted kidney. Radical nephrectomy of the graft harboring the tumor with preservation of the adjacent functioning graft was done and identified to be chromophobe RCC. After two-year follow-up, the patients had a perfect graft function with no evidence of oncological failure. We suggest that allograft tumor be considered in patient evaluation for hematuria. Regular follow-up imaging of transplanted kidney is mandatory even after graft failure for early detection of graft tumors.

2.
J Environ Manage ; 242: 384-393, 2019 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-31059951

RESUMO

The sole, dual and multi-fermentations of fruit and vegetable peels (FVPs) were investigated in order to balance nutrition hierarchy for maximizing hydrogen potential via Batch experiments. The highest volumetric hydrogen production of 2.55 ± 0.07 L/L and hydrogen content of 64.7 ± 3.7% were registered for multi-fermentation of M-PTBO (25% pea +25% tomato + 25% banana +25% orange). These values outperformed sole and dual fermentation. The multi-fermentation of FVPs provided sufficient nutrients and trace elements for anaerobes, where C/N and C/P ratios were at levels of 24.7 ± 0.2 and 113.2 ± 9.4, respectively. In specific, harmonizing of macro and micro-nutrients remarkably maximized activities of amylase, protease and lipase to 4.23 ± 0.42, 0.035 ± 0.002 and 0.31 ± 0.02 U/mL, respectively, as well as, substantially incremented counts of Clostridium and Enterobacter sp. up to 5.81 ±â€¯0.23 × 105 and 2.17 ±â€¯0.09 × 106 cfu/mL, respectively. Furthermore, multi-fermentation of M-PTBO achieved the maximum net energy gain and profit of 1.82 kJ/gfeedstock and 4.11 $/kgfeedstock, respectively. Nutrients balance significantly develops bacterial activity in terms of hydrogen productivity, anaerobes reproduction, enzyme activities and soluble metabolites. As a result, overall fermentation bioprocess performance was improved.


Assuntos
Frutas , Verduras , Fermentação , Hidrogênio , Nutrientes
3.
Environ Sci Pollut Res Int ; 26(10): 10429-10438, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30811023

RESUMO

The aim of this study is to assess an innovative economic approach for the production of both fermentative hydrogen and biochar from fruit and vegetable peels (FVPs) via fermentation/pyrolysis process. Firstly, in fermentation batches, multi-fermentation of FVPs positively affected the harvested hydrogen yield and COD reduction efficiency, which reached their maximal values of 3.9 ± 0.6 mmol/gCOD and 56.2 ± 4.6% at batch of 25% pea + 25% tomato + 25% banana + 25% orange (M4). Secondly, digestates produced from all batches were pyrolyzed at 500 °C for investigating the potential for biochar production. Based on the characteristics of the pyrolyzed digestate, biochar produced from S1 (spinach) exhibited the highest specific surface area, density, pore volume, biochar production yield, and pyrolysis profit of 28.43 ± 3.95 m2/g, 1.93 ± 0.18 g/cm3, 0.59 ± 0.08 cm3/g, 59.04 ± 2.36%, and 3.66 $/kgfeedstock, respectively. However, the maximum overall profit from both fermentation and pyrolysis processes was 5.21 $/kgfeedstock and was denoted for M4.


Assuntos
Fermentação , Alimentos , Eliminação de Resíduos/métodos , Resíduos , Carvão Vegetal , Frutas , Hidrogênio , Pirólise , Verduras
5.
Urology ; 121: 58-65, 2018 11.
Artigo em Inglês | MEDLINE | ID: mdl-30031005

RESUMO

OBJECTIVE: To assess the non-inferiority of Low-power Holmium laser enucleation of the prostate (LP-HoLEP) to high-power (HP-HoLEP) for enucleation efficiency pertaining to the advantages of lower cost and minimal postoperative dysuria, storage symptoms, and negative sexual impact. PATIENTS AND METHODS: HoLEP was performed using 100W Versapulse, Luminis Inc., with 2J/25Hz for LP-HoLEP (61 patients) and 2J/50Hz for HP-HoLEP (60 patients). Two surgeons with different experience performed equal number of both procedures. Non-inferiority of enucleation efficiency (enucleated weight/min) was evaluated. All perioperative parameters were recorded and compared. Dysuria was assessed at 2 weeks by dysuria visual analog scale, urinary (Q.max and IPSS) and sexual (sexual health inventory for men score) outcome measures were evaluated at 1, 4, and 12 months. RESULTS: Baseline and perioperative parameters were comparable between the two groups. Mean enucleation efficiency was 1.42±0.6 vs 1.47±0.6 gm/min, P = .6 following LP-HoLEP and HP-HoLEP, respectively. Patients reported postoperative dysuria similarly in both groups as per dysuria visual analog scale. There was significant comparable improvement in IPSS (international prostate symptom score) and Q.max in both groups at different follow-up points. At one year, median IPSS and Q.max were comparable in both groups (P = .4 and .7 following LP-HoLEP and HP-HoLEP, respectively). Median postoperative reduction in prostate specific antigen was 89% (42:99) following LP-HoLEP vs 81% (62:94) after HP-HoLEP, P = .92. Both groups showed comparable perioperative and late postoperative complications. There were no statistically significant changes in the last follow-up sexual health inventory for men score in comparison to baseline score. CONCLUSION: LP-HoLEP is non-inferior to HP-HoLEP in terms of all efficiency parameters regardless level of surgeon experience.


Assuntos
Disuria , Terapia a Laser , Lasers de Estado Sólido/uso terapêutico , Complicações Pós-Operatórias , Hiperplasia Prostática , Qualidade de Vida , Disfunções Sexuais Fisiológicas , Ressecção Transuretral da Próstata , Idoso , Disuria/diagnóstico , Disuria/etiologia , Disuria/psicologia , Humanos , Terapia a Laser/efeitos adversos , Terapia a Laser/instrumentação , Terapia a Laser/métodos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/psicologia , Próstata/diagnóstico por imagem , Próstata/patologia , Próstata/cirurgia , Hiperplasia Prostática/diagnóstico , Hiperplasia Prostática/psicologia , Hiperplasia Prostática/cirurgia , Disfunções Sexuais Fisiológicas/diagnóstico , Disfunções Sexuais Fisiológicas/etiologia , Disfunções Sexuais Fisiológicas/psicologia , Ressecção Transuretral da Próstata/efeitos adversos , Ressecção Transuretral da Próstata/instrumentação , Ressecção Transuretral da Próstata/métodos , Resultado do Tratamento , Escala Visual Analógica
6.
Urology ; 117: 131-136, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29649545

RESUMO

OBJECTIVE: To demonstrate the long-term outcome of a contemporary series of 64 children who underwent complete primary repair of bladder exstrophy (CPRE) in a single tertiary referral center. MATERIALS AND METHODS: Between 1998 and 2012, 64 children, 47 boys and 17 girls, were identified. Only 60 of the 64 cases were available for follow-up. The follow-up was done by renal bladder ultrasound and serum creatinine every 3 months and voiding cystourethrogram from 6 to 12 months postoperatively. Continence was defined as dryness ≥3 hours. RESULTS: Median (range) follow-up is 14 years (from 5 to 19 years). Voided continence was achieved in 14 children (23%) after CPRE only. Additionally, 6 children were continent after bladder neck reconstruction (BNR) and 2 after bladder neck injection (BNI), raising the percentage of voided continence to 36%. The remaining 38 (64%) patients were using clean intermittent catheterization. All cases were continent at last assessment. The results of BNR or BNI were better in de novo than in redo cases (P <.05). The percentage of cases that needed augmentation ileocystoplasty in combination with multiple bladder neck procedures was lower in both female and de novo cases (P <.05). CONCLUSION: The percentage of children with classic bladder exstrophy who underwent CPRE who will achieve continence with volitional voiding via the urethra is 36%. The continence results after BNR and BNI are better in de novo cases than in redo ones. Continence in female and de novo cases is more likely to be achieved with lower number of continence procedures.


Assuntos
Extrofia Vesical/fisiopatologia , Extrofia Vesical/cirurgia , Bexiga Urinária/diagnóstico por imagem , Bexiga Urinária/fisiopatologia , Incontinência Urinária/etiologia , Extrofia Vesical/complicações , Pré-Escolar , Creatinina/sangue , Feminino , Humanos , Lactente , Recém-Nascido , Cateterismo Uretral Intermitente , Masculino , Procedimentos Cirúrgicos Reconstrutivos , Reoperação , Fatores de Tempo , Resultado do Tratamento , Ultrassonografia , Bexiga Urinária/cirurgia , Micção , Procedimentos Cirúrgicos Urogenitais
7.
Vet Microbiol ; 208: 89-93, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-28888656

RESUMO

In January-April 2016, cattle and buffalo farm owners and veterinarians reported clinical signs suggestive of foot and mouth disease virus (FMDV) outbreaks among non-vaccinated cattle and buffalo herds in Egypt. The clinical disease observed was either mild (small oral lesions and speedy recovery) or severe (extensive oral lesions and/or mortalities), and the form of the disease (either mild or severe) segregated by farm. This study aimed to confirm the presence of FMDV and to characterize the circulating strains associated with the outbreaks. Vesicular epithelia were collected from 41 animals representing 15 affected cattle and buffalo farms in five governorates (Behira, Cairo, Daqahlia, Giza and Ismailia), and tested by real time (rt) RT-PCR. Consequently, 92% (38/41) of examined samples were positive. Furthermore, the VP1 coding region of 60% (23/38) of positive specimens were amplified by RT-PCR and sequenced. The phylogenetic analysis identified two distinct strains characterized as serotype O topotype EA-3 and serotype A (African topotype) of genotype IV in the severe and mild disease forms, respectively. The newly identified strains clustered in distinct clades in the phylogenetic trees, indicating the likelihood of new incursions into Egypt. Those strains were most closely related to previously described Sudanese strains.


Assuntos
Búfalos/virologia , Doenças dos Bovinos/virologia , Surtos de Doenças/veterinária , Vírus da Febre Aftosa/genética , Febre Aftosa/virologia , Animais , Bovinos , Doenças dos Bovinos/epidemiologia , Egito/epidemiologia , Febre Aftosa/epidemiologia , Sorogrupo
8.
Int Urol Nephrol ; 49(8): 1327-1334, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28501912

RESUMO

PURPOSE: To evaluate the long-term renal function outcome of management of retroperitoneal fibrosis (RPF)-induced ureteral obstruction. METHODS: Thirty-six patients with idiopathic RPF-induced ureteral obstruction were classified according to the management type into two groups, group A; managed by indwelling JJ stent and group B managed by ureterolysis and omental wrapping (UOR). The primary outcome was to define the long-term outcome of management on RF. It was evaluated by changes in serum creatinine and estimated GFR (eGFR) using Modification of Diet in Renal Disease equation where 20% changes in eGFR is considered significant. The second outcome is to compare the outcomes between both groups. RESULTS: After 27.5 (1-124) months, median (range) follow-up, median (range) serum creatinine increased significantly from 1.5 (0.8-8.1) to 1.6 (1-12.1) mg/dl (p value =0.04) and eGFR showed non-statistical significant reduction from 43 (5-110) to 41 (5-88) ml/min/1.73 m2 (p value =0.3). Eight (22.2%), 12 (34.4%) and 16 (44.4%) patients showed stable, increased and decreased eGFR. Group A showed statistically significant increased serum creatinine and insignificant decreased eGFR (p value =0.04 and 0.09), while group B showed statistically insignificant changes in serum creatinine and eGFR (p value =0.5 and 0.9). In group B, nine (21.4%) renal units are still harboring JJ stents. CONCLUSION: For idiopathic RPF, UOR avoided indwelling ureteral stents in 78.6% of renal units with apparent better long-term renal function outcome.


Assuntos
Fibrose Retroperitoneal/complicações , Stents , Obstrução Ureteral/fisiopatologia , Obstrução Ureteral/cirurgia , Adulto , Creatinina/sangue , Feminino , Seguimentos , Taxa de Filtração Glomerular , Humanos , Masculino , Pessoa de Meia-Idade , Insuficiência Renal Crônica/etiologia , Estudos Retrospectivos , Fatores de Tempo , Obstrução Ureteral/etiologia
9.
J Virol Methods ; 235: 99-104, 2016 09.
Artigo em Inglês | MEDLINE | ID: mdl-27180038

RESUMO

There is no gold standard for detection of Rotavirus Group A (RVA), one of the main causes of diarrhea in neonatal animals. Sensitive and specific real-time RT-PCR (rtRT-PCR) assays are available for RVA but require submission of the clinical samples to diagnostic laboratories. Patient-side immunoassays for RVA protein detection have shown variable results, particularly with samples from unintended species. A sensitive and specific test for detection of RVA on the farm would facilitate rapid management decisions. The insulated isothermal RT-PCR (RT-iiPCR) assay works in a portable machine to allow sensitive and specific on-site testing. The aim of this investigation was to evaluate a commercially available RT-iiPCR assay for RVA detection in feces from different animal species. This assay was compared to an in-house rtRT-PCR assay and a commercially available rtRT-PCR kit, as well as an ELISA and EM for RVA detection. All three PCR assays targeted the well-conserved NSP5 gene. Clinical fecal samples from 108 diarrheic animals (mainly cattle and horses) were tested. The percentage of positive samples by ELISA, EM, in-house rtRT-PCR, commercial rtRT-PCR, and RT-iiPCR was 29.4%, 31%, 36.7%, 51.4%, 56.9%, respectively. The agreement between different assays was high (81.3-100%) in samples containing high viral loads. The sensitivity of the RT-iiPCR assay appeared to be higher than the commercially available rtRT-PCR assay, with a limit of detection (95% confidence index) of 3-4 copies of in vitro transcribed dsRNA. In conclusion, the user-friendly, field-deployable RT-iiPCR system holds substantial promise for on-site detection of RVA.


Assuntos
Ensaio de Imunoadsorção Enzimática , Fezes/virologia , Microscopia Eletrônica , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Infecções por Rotavirus/veterinária , Rotavirus/isolamento & purificação , Animais , Bovinos , Doenças dos Bovinos/diagnóstico , Doenças dos Bovinos/virologia , Diarreia/virologia , Doenças dos Cavalos/diagnóstico , Doenças dos Cavalos/virologia , Cavalos , Sistemas Automatizados de Assistência Junto ao Leito , RNA de Cadeia Dupla , RNA Viral/genética , RNA Viral/isolamento & purificação , Kit de Reagentes para Diagnóstico , Reação em Cadeia da Polimerase em Tempo Real , Rotavirus/genética , Infecções por Rotavirus/diagnóstico , Infecções por Rotavirus/virologia , Sensibilidade e Especificidade , Temperatura Ambiente , Carga Viral , Proteínas não Estruturais Virais/genética
10.
Genome Announc ; 3(6)2015 Dec 23.
Artigo em Inglês | MEDLINE | ID: mdl-26701085

RESUMO

Here, we report the complete genome sequence of bovine viral diarrhea virus-1b (BVDV-1b), strain Egy/Ismailia/2014. The virus genome is composed of 12,217 nucleotides organized as one open reading frame encoding 3,898 amino acids. This report will assist efforts in diagnostics, studying molecular epidemiology, and control of BVDV in Egypt.

11.
J Infect Dev Ctries ; 9(12): 1331-7, 2015 Dec 30.
Artigo em Inglês | MEDLINE | ID: mdl-26719939

RESUMO

INTRODUCTION: Bovine viral diarrhea (BVD) is one of the most economically significant diseases in the bovine industry causing losses due to diarrhea, reproductive disorders, immunosuppression and mortalities. The aim of our investigation was to detect and subtype BVDV from calves on two dairy cattle and two buffalo farms in Ismailia province, Egypt as an indicator of BVDV infection status in the province. METHODOLOGY: A total of 298 blood samples were collected and tested using an optimized one-step, real-time multiplex Taqman-based RT-PCR. All the positive samples by the multiplex real-time RT-PCR were tested using conventional RT-PCR to amplify multiple areas of the genome for further phylogenetic analysis and subtyping. RESULTS: Thirty one (10.4%) of the tested samples were positive for BVDV-1. Only three samples, all from a single dairy cattle farm, had enough viral RNA to be amplified by RT-PCR. The PCR products were sequenced and phylogenetic analysis revealed detection of BVDV-1b. The detected strain is closely related to worldwide BVDV-1b strains, making it difficult to trace its origin. Nucleotide and amino acid alignments of the E2 glycoprotein region of the detected strain with other BVDV-1b strains showed high divergence, with identity ranging from 81.3% to 93.6% and 85.3% to 93.6%, respectively. CONCLUSION: To our knowledge, this is the first report describing the circulation of BVDV-1b in Egyptian dairy cattle populations.


Assuntos
Doenças dos Bovinos/epidemiologia , Doenças dos Bovinos/virologia , Vírus da Diarreia Viral Bovina Tipo 1/classificação , Vírus da Diarreia Viral Bovina Tipo 1/isolamento & purificação , Genótipo , Infecções por Pestivirus/veterinária , Agricultura , Animais , Sangue/virologia , Búfalos , Bovinos , Vírus da Diarreia Viral Bovina Tipo 1/genética , Egito/epidemiologia , Técnicas de Genotipagem , Epidemiologia Molecular , Reação em Cadeia da Polimerase Multiplex , Infecções por Pestivirus/epidemiologia , Infecções por Pestivirus/virologia , Reação em Cadeia da Polimerase em Tempo Real , Reação em Cadeia da Polimerase Via Transcriptase Reversa
12.
Infect Genet Evol ; 28: 44-7, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25200722

RESUMO

Peste des petits ruminants (PPR) is an acute, highly contagious fatal disease of small ruminants characterized by high fever, ocular and nasal discharge, pneumonia, erosive stomatitis and severe enteritis that ultimately results in high mortalities. Peste des petits ruminants virus (PPRV) is widely distributed and endemic in several African, middle eastern and south Asian countries and it poses a threat to European countries. Egyptian veterinary medical authorities stated that Egypt is free from PPRV and the only measures for disease control are test and slaughter of infected population to maintain the free status. The aim of our investigation was to detect PPRV in Ismailia province as an indicator of the infection status in Egypt and perform molecular characterization of the emerging virus to gain insight into the origin of circulating virus. A total of 40 representative clinical samples, from a single goat case and goat flock in 2010 and sheep flock in 2012, were tested for PPRV by RT-PCR. About 21 (52.5%) samples were positive. The phylogenetic analysis of the detected viruses revealed circulation of PPRV lineage IV. The circulating viruses are closely related to Sudanese and Saudia Arabian strains with nucleotide identity ranged from 99.2% to 99.6%, respectively. Also, it is closely related to Moroccan 2008 viruses with identities ranged from 97.6% to 98%. Epidemiological investigation at the national level is recommended for monitoring PPRV spread and implementing an appropriate control program.


Assuntos
Doenças Transmissíveis Emergentes , Peste dos Pequenos Ruminantes/epidemiologia , Peste dos Pequenos Ruminantes/virologia , Vírus da Peste dos Pequenos Ruminantes/classificação , Vírus da Peste dos Pequenos Ruminantes/genética , Animais , Surtos de Doenças , Egito/epidemiologia , Genes Virais , Dados de Sequência Molecular , Morbidade , Mortalidade , Peste dos Pequenos Ruminantes/mortalidade , Filogenia , RNA Viral , Análise de Sequência de DNA
13.
Int J Gynaecol Obstet ; 116(2): 143-7, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22114785

RESUMO

OBJECTIVE: To determine the association of hemoglobin (Hb) and plasma nitrite (PN) concentrations on admission to the delivery ward with the occurrence of atonic postpartum hemorrhage (PPH). METHODS: Of 319 women admitted to the Department of Obstetrics and Gynecology, Dayrout General Hospital, Assiut, Egypt, for delivery in July 2010, 200, who were not considered to be at risk of atonic PPH, were eligible for inclusion. Plasma levels of Hb and nitrite were measured on admission. The third stage of labor was actively managed. RESULTS: A total of 22 participants had significantly raised PN levels (P<0.001), 12 of whom developed PPH-with Hb levels of 9 g/dL or less and nitric oxide (NO) levels of 180 µM/L or greater. The other 10 women underwent over 6 hours of stressful labor prior to hospital admission. CONCLUSION: Even moderate anemia can raise levels of NO and enhance its biologic effects, which in turn can result in uterine muscle relaxation and atonic PPH. Preventing or treating anemia during pregnancy could avoid these complications.


Assuntos
Anemia/complicações , Óxido Nítrico/metabolismo , Hemorragia Pós-Parto/etiologia , Inércia Uterina/etiologia , Adolescente , Adulto , Egito , Feminino , Hemoglobinas/metabolismo , Humanos , Trabalho de Parto , Pessoa de Meia-Idade , Miométrio/metabolismo , Nitritos/sangue , Gravidez , Complicações Hematológicas na Gravidez/patologia , Fatores de Tempo , Adulto Jovem
14.
J Obstet Gynaecol Res ; 37(11): 1557-63, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21676082

RESUMO

AIM: To compare maternal mortality and morbidity due to postpartum hemorrhage (PPH) at Minia University Maternity Hospital, El-Minia, Egypt, before and while external aortic compression was applied as an adjunct intervention, and to identify the effect of aortic compression. METHODS: The obstetric data and outcomes of women with PPH were compared for the period 1999 through 2007, when only a regular PPH management protocol was followed, and for 2008 through 2009, when external aortic compression was applied before initiating the protocol. The El-Minia aortic compression device (EACD) was used in 2008 and the manual aortic compression maneuver (MACM) in 2009. Outcomes and treatment measures were analyzed by the ×2 test and multivariate regression. RESULTS: During the first period, PPH annually caused 1-6 deaths and 22-31 severe conditions, such as acute renal failure, loss of consciousness, anemia persisting after treatment, postpartum infection, or the need for a hysterectomy. The incidence of PPH declined from 4.6% in 1999 to 0.9% at the end of the study. In 2008 and 2009, there were no deaths due to PPH and only four complications were recorded in each of these two years. Regression analysis identified aortic compression as the second most effective measure preventing severe shock and death, with blood transfusions being the first. The almost similar results reached with the EACD and MACM allow a choice, but fewer units of blood were needed following application of the device. CONCLUSIONS: Including the EACD and MACM in the regular management protocol may improve the outcome of severe PPH.


Assuntos
Técnicas Hemostáticas , Hemorragia Pós-Parto/terapia , Adulto , Egito , Feminino , Maternidades , Humanos , Mortalidade Materna , Hemorragia Pós-Parto/mortalidade
15.
Int J Gynaecol Obstet ; 110(3): 257-61, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20605150

RESUMO

OBJECTIVE: To monitor femoral artery blood flow by Doppler velocimetry in women treated for postpartum hemorrhage (PPH) with and without the adjunction of the External Aortic Compression Device (EACD), and to assess the possible adverse effects of the device. METHODS: Blood flow velocity in the femoral artery, as well as skin color and sensory or motor changes in the lower limbs, were assessed in 120 women with primary PHH of any cause, quasi randomized to either treatment group. Pulse rate, oxygen saturation, respiratory rate, urinary output, and gastrointestinal symptoms were checked in the study group. RESULTS: While blood flow velocity was significantly less in the study group than control group (P<0.001), the lowest flow volume velocity of 310.40 mL/sec exceeded the acceptable minimum after device application. The intensity of abdominal discomfort correlated with body mass index. No device complications were observed. CONCLUSION: The EACD contributed safely and effectively to the treatment of 60 women with PPH of different causes.


Assuntos
Artéria Femoral/fisiologia , Técnicas Hemostáticas/instrumentação , Hemorragia Pós-Parto/terapia , Adolescente , Adulto , Velocidade do Fluxo Sanguíneo , Feminino , Técnicas Hemostáticas/efeitos adversos , Humanos , Hemorragia Pós-Parto/diagnóstico por imagem , Gravidez , Fluxo Sanguíneo Regional , Reologia , Resultado do Tratamento , Ultrassonografia Doppler de Pulso , Adulto Jovem
16.
J Obstet Gynaecol Res ; 35(3): 453-8, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19527382

RESUMO

AIM: To evaluate the external aortic compression device (EACD) as a first aid to control postpartum hemorrhage (PPH). METHODS: Three hundred women whose deliveries were complicated with PPH were recruited into a quasi-randomization study. Groups comprised 120 women each who had atonic PPH. The EACD was used together with traditional management in study women, while traditional management alone was used in control women. Outcome measures were maternal mortality, morbidity (hysterectomy), amount of blood transfusion (BT), uterotonic drugs and time to stop bleeding. Side effects of the EACD were assessed. Atonic PPH was defined as a blood loss of >or=500 mL from an atonic uterus with circulatory compromise within 24 hrs of childbirth. Controls were treated with i.v. access, nasal oxygen, fresh BT, uterine massage, El-Menia air inflated balloon and uterotonic drugs. Study women were treated using EACD together with conventional management. RESULTS: Time to stop bleeding was significantly shorter (36.8 +/- 23.4 vs 118.6 +/- 36.8 min) in study women than in control women (P < 0.001); 87.5% of study women, but no single woman in the control group had their bleeding stopped within the first 45 min of PPH onset. No morbidities or mortality among those who received EACD compared with control women, among who had five surgical hysterectomies and one mortality. The amount of BT units (302 vs 200), ergometrine ampoules (3.6 +/- 0.5 vs 2.5 +/- 0.8), syntocinon units (30.6 +/- 0.5 vs 20.5 +/- 0.8) and misoprostol tablets (6.7 +/- 1.8 vs 3.8 +/- 0.7) received were significantly more in the control group than in the study group (P < 0.001). Adverse effects of EACD were rarely observed. CONCLUSION: EACD is a cost-effective and easily applied maneuver that allows satisfactory management of PPH without maternal mortality or morbidity. It is of value in developing countries.


Assuntos
Obstetrícia/instrumentação , Hemorragia Pós-Parto/prevenção & controle , Adulto , Transfusão de Sangue , Feminino , Humanos , Histerectomia , Mortalidade Materna , Gravidez , Fatores de Tempo , Resultado do Tratamento , Inércia Uterina/diagnóstico , Inércia Uterina/tratamento farmacológico
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA