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1.
Medicine (Baltimore) ; 98(22): e15707, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-31145284

RESUMO

INTRODUCTION: Magnetic resonance (MR) relaxometry provides a noninvasive predictive tool to discriminate between benign ovarian endometrioma (OE) and endometriosis-associated ovarian cancer (EAOC). Transverse relaxation rate R2 value was determined using a single-voxel, multi-echo MR sequence (HISTO) by a 3T-MR system. R2 with cutoff value of 12.1 s was established to discriminate between benign and malignant tumors. PATIENT CONCERNS: We present a case of a 39-year-old woman who was initially thought to be malignant transformation of endometriosis by diagnostic MR imaging of the vascularized solid components. DIAGNOSIS: A R2 value of 42.62 s on MR relaxometry demonstrated that this case is non-malignant. INTERVENTIONS: To confirm the diagnose, left salpingo-oophorectomy by laparoscopic surgery was performed. OUTCOMES: Histopathological results revealed seromucinous borderline tumor (SMBT). Our experience suggests that preoperative MR relaxometry may be useful for discriminating "borderline (SMBT)" from "malignancy (EAOC)." Furthermore, immunohistochemical studies of this case demonstrated ovarian SMBT cells were positive for estrogen receptor, progesterone receptor, and hepatocyte nuclear factor-1beta. A similar expression pattern was also observed in patients with benign OE. LESSONS: In many respects, SMBT characteristics differ from those of EAOC but resemble those of benign OE. MR relaxometry unveils a new clinical approach as an adjunctive modality for discriminating SMBT from EAOC.


Assuntos
Neoplasias do Endométrio/diagnóstico por imagem , Endometriose/diagnóstico por imagem , Espectroscopia de Ressonância Magnética/estatística & dados numéricos , Neoplasias Císticas, Mucinosas e Serosas/diagnóstico por imagem , Neoplasias Ovarianas/diagnóstico por imagem , Adulto , Diagnóstico Diferencial , Endometriose/complicações , Feminino , Humanos , Espectroscopia de Ressonância Magnética/métodos , Neoplasias Císticas, Mucinosas e Serosas/etiologia , Neoplasias Ovarianas/etiologia , Ovário/diagnóstico por imagem , Ovário/patologia , Valores de Referência , Salpingo-Ooforectomia
2.
Case Rep Obstet Gynecol ; 2017: 4187416, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28154764

RESUMO

Mullerian adenosarcoma (MA) is a rare tumor variant with low malignancy potential and is reported to account for 8% of all uterine sarcomas. Cervical MAs are reported to occur in relatively younger patients with the mean age of 27 years, while those in the uterine corpus generally present in postmenopausal women. Due to the rarity of cervical MAs, optimal management for these patients (especially younger women) is still under exploration. Here, we describe a case of cervical MA in a woman of reproductive age who was treated by fertility-preserving surgery and successfully delivered a child 18 months later.

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