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1.
Kardiologiia ; 61(6): 41-51, 2021 Jul 01.
Artigo em Russo, Inglês | MEDLINE | ID: mdl-34311687

RESUMO

Aim      To study features of diagnosis and treatment of acute myocardial infarction (AMI) in Russian hospitals, results of the treatment, and early and late outcomes (6 and 12 months after AMI diagnosis); to evaluate the consistence of the treatment with clinical guidelines; and to evaluate patients' compliance with the treatment.Material and methods  The program was designed for 3 years, including 24 months for recruitment of patients to the study. The study will include 10, 000 patients hospitalized with a confirmed diagnosis (I21 according to ICD-10) of ST segment elevation acute myocardial infarction (MI) (STEMI) or non-ST segment elevation MI (NSTEMI) based on criteria of the European Society of Cardiology Guidelines on Forth Universal Definition of Myocardial Infarction (2018). The follow-up period was divided into three stages: observation during the stay in the hospital and at 6 and 12 months following inclusion into the registry. The primary endpoint included cardiac death, nonfatal MI during the hospitalization and after one-year follow-up. Secondary endpoints were 6-months and one-year incidence of repeated MI, heart failure, ischemic stroke, clinically significant hemorrhage, unscheduled revascularization after discharge from the hospital, and the proportion of patients who continue on statins, antiplatelet drugs, and drugs of other groups for 6 months and 1 year.Results The inclusion of patients into the registry started in 2020 and will continue for 24 months. By the time of the article publication (June, 2021), more than 2,000 patients will be included.Conclusion      REGION-MI (Russian rEGIstry Of acute myocardial iNfarction) is a multicenter, retrospective and prospective observational cohort study that excludes any interference with the clinical practice. Results of the registry will help to analyze a real picture of medical care provided to patients with myocardial infarction and to schedule ways to improve the situation.


Assuntos
Infarto do Miocárdio , Humanos , Infarto do Miocárdio/diagnóstico , Infarto do Miocárdio/epidemiologia , Infarto do Miocárdio/terapia , Estudos Prospectivos , Sistema de Registros , Estudos Retrospectivos , Fatores de Risco , Federação Russa/epidemiologia , Fatores de Tempo , Resultado do Tratamento
4.
Med Radiol (Mosk) ; 29(10): 34-7, 1984 Oct.
Artigo em Russo | MEDLINE | ID: mdl-6548787

RESUMO

An analysis of the results of treatment of 108 patients with Hodgkin's disease, Stage III, has shown a high efficacy of multiple modality treatment in children followed-up for 5 yrs. A comparative analysis of the results of the therapeutic programs (2 groups of patients) has shown advantages of the therapeutic program using COPP or CVPP chemotherapy programs for inducing remission which when combined with splenectomy and radiotherapy makes it possible to achieve 5-year survival in 86.6% of children.


Assuntos
Doença de Hodgkin/radioterapia , Adolescente , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Criança , Pré-Escolar , Terapia Combinada , Ciclofosfamida/administração & dosagem , Feminino , Seguimentos , Doença de Hodgkin/mortalidade , Doença de Hodgkin/patologia , Doença de Hodgkin/terapia , Humanos , Lomustina/administração & dosagem , Masculino , Prednisona/administração & dosagem , Procarbazina/administração & dosagem , Dosagem Radioterapêutica , Recidiva , Esplenectomia , Vimblastina/administração & dosagem , Vincristina/administração & dosagem
6.
Med Radiol (Mosk) ; 28(6): 17-20, 1983 Jun.
Artigo em Russo | MEDLINE | ID: mdl-6865681

RESUMO

An analysis of the clinical data on 183 children who were treated for Hodgkin's disease, and and 7-year follow-up have shown that the determination of a morphological variant is an indispensable part of clinical diagnosis. However prognosis, long- and short-term results depend not on a morphological variant but on the degree of dissemination of a pathological process by the time of the initiation of treatment.


Assuntos
Doença de Hodgkin/classificação , Adolescente , Criança , Pré-Escolar , Feminino , Seguimentos , Doença de Hodgkin/mortalidade , Doença de Hodgkin/radioterapia , Humanos , Masculino , Estadiamento de Neoplasias , Prognóstico
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