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J Nucl Med ; 59(6): 967-972, 2018 06.
Artigo em Inglês | MEDLINE | ID: mdl-29097408


Chronic sciatica is a major cause of disability worldwide, but accurate diagnosis of the causative pathology remains challenging. In this report, the feasibility of an 18F-FDG PET/MRI approach for improved diagnosis of chronic sciatica is presented. Methods:18F-FDG PET/MRI was performed on 9 chronic sciatica patients and 5 healthy volunteers (healthy controls). Region-of-interest analysis using SUVmax was performed, and 18F-FDG uptake in lesions was compared with that in the corresponding areas in healthy controls. Results: Significantly increased 18F-FDG uptake was observed in detected lesions in all patients and was correlated with pain symptoms. 18F-FDG-avid lesions not only were found in impinged spinal nerves but also were associated with nonspinal causes of pain, such as facet joint degeneration, pars defect, or presumed scar neuroma. Conclusion: The feasibility of 18F-FDG PET/MRI for diagnosing pain generators in chronic sciatica was demonstrated, revealing various possible etiologies.

Fluordesoxiglucose F18 , Imagem por Ressonância Magnética , Imagem Multimodal , Tomografia por Emissão de Pósitrons , Ciática/diagnóstico por imagem , Coluna Vertebral/diagnóstico por imagem , Adulto , Doença Crônica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Dor/complicações , Ciática/complicações , Adulto Jovem