Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 32
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Trop Anim Health Prod ; 51(7): 2109-2114, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31161484

RESUMO

The aim of this study was to clarify the causes of scrotal enlargement in rams and bucks in Qassim region of Saudi Arabia. Enlarged scrotal contents of rams and bucks (n = 153) were examined by visual inspection, palpation, and ultrasonography. Blood samples were obtained and tested for Brucella sp. infection. Clinical and ultrasonographic findings showed that scrotal enlargement was mainly associated with orchitis, peri-orchitis, and epididymitis. Miscellaneous findings were scrotal hernia, scrotal hematoma, and hydrocele. The frequencies of orchitis, peri-orchitis, and epididymitis were 47.4, 21.1, and 14.1% in Awassi rams; 54.5, 21.7, and 8.7% in Najdi rams; 52.3, 20.5, and 9.1% in Ardi bucks; and 50, 16.7, and 16.7% in Damascus bucks, respectively. Orchitis was associated with no-abscess formation (23%), single-abscess formation (15.4%), and multiple-abscesses formation (61.6%). Peri-orchitis was characterized by hard consistency, atrophy of the testes, and extensive connective tissue formation. Epididymitis was observed mainly at the tail of the epididymis (82.4%) but rarely at the head (17.6%). Epididymitis was associated in many cases with abscessation (70.6%). Males with orchitis, peri-orchitis, and epididymitis were positive for Brucella melitensis and Brucella ovis in the frequency of 21.3% and 48.8%, respectively. In conclusion, scrotal enlargement in rams and bucks in Qassim region is caused mainly by inflammation of the testis and/or epididymis and associated tremendously with brucellosis seropositivity.


Assuntos
Brucelose/veterinária , Epididimite/veterinária , Orquite/veterinária , Doenças dos Ovinos/microbiologia , Animais , Atrofia , Brucella melitensis , Brucelose/diagnóstico , Brucelose/microbiologia , Inflamação , Masculino , Orquite/diagnóstico , Orquite/microbiologia , Arábia Saudita , Estudos Soroepidemiológicos , Ovinos , Doenças dos Ovinos/diagnóstico , Carneiro Doméstico , Ultrassonografia
2.
World J Urol ; 36(11): 1877-1881, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-29766318

RESUMO

PURPOSE: To evaluate the role of sildenafil in relieving ureteral stent symptoms. PATIENTS AND METHODS: A randomized controlled trial was conducted between March 2014 and November 2016. It included adult men who underwent unilateral ureteric stent after ureteroscopy. Patients who were taking PDE5-Is, alpha-blockers or anticholinergics, had contraindication to sildenafil or developed postoperative complications were not included. Eligible patients were randomized using sealed closed envelops to one of two groups (S and C). Patients in group S received sildenafil citrate 50 mg tablet once daily. Patients in group C were the control. All patients answered the ureteral stent symptom questionnaire (USSQ) after 2 weeks of stenting. Primary outcome was the difference in total USSQ score between both groups. Secondary outcomes were tolerability of the treatment and the difference in each domain of USSQ score. RESULTS: After randomization, four patients (7.3%) in group C withdraw their consent because of severe symptoms and two patients (3.6%) in group S discontinued treatment because of headache and dizziness. Final analysis was performed for 46 and 48 patients in groups C and S, respectively. Total USSQ score and all domains (except work performance) were significantly lower in group S (P < 0.001). Dysuria and urgency were significantly more in group C (P = 0.012 and 0.007, respectively). Three patients in groups S (6.25%) experienced transient mild adverse effects (dyspepsia, flushing and rhinitis in one patient for each) but they continued sildenafil. CONCLUSIONS: Sildenafil is an effective and well-tolerated treatment option for relieving ureteral stent-related symptoms in men. CLINICALTRIAL. GOV IDENTIFIER: NCT02345980.


Assuntos
Sintomas do Trato Urinário Inferior/tratamento farmacológico , Inibidores da Fosfodiesterase 5/uso terapêutico , Complicações Pós-Operatórias/tratamento farmacológico , Citrato de Sildenafila/uso terapêutico , Stents , Cálculos Ureterais/cirurgia , Ureteroscopia , Adulto , Disuria/tratamento farmacológico , Hematúria/tratamento farmacológico , Humanos , Masculino , Pessoa de Meia-Idade , Noctúria/tratamento farmacológico , Complicações Pós-Operatórias/fisiopatologia , Qualidade de Vida , Inquéritos e Questionários , Resultado do Tratamento , Ureter , Incontinência Urinária de Urgência/tratamento farmacológico
3.
J Vet Med Sci ; 80(5): 778-783, 2018 May 18.
Artigo em Inglês | MEDLINE | ID: mdl-29563349

RESUMO

This report summarizes the clinical, hematobiochemical, ultrasonographic, histopathological and bacteriological findings in a male Arabian camel (Camelus dromedarius) with bilateral renal abscessation and chronic active pyelonephritis. Owner complaint included a decreased appetite and loss of body condition with occasionally voiding red urine. In the right kidney, ultrasonographic changes included a hypoechoic fluid surrounding the renal parenchyma. Within the left kidney, a large volume of hypoechoic contents were imaged. Bacteriological examination yielded only Escherichia coli. To the authors' knowledge this is the first reported case of bilateral renal abscessation and chronic active pyelonephritis in dromedary camels. In conclusion, renal ultrasonography provides a precise and non-invasive technique for diagnosis and subsequent clinical decision making of renal abscessation and chronic pyelonephritis camels.


Assuntos
Abscesso Abdominal/veterinária , Camelus , Infecções por Escherichia coli/veterinária , Nefropatias/veterinária , Pielonefrite/veterinária , Abscesso Abdominal/microbiologia , Abscesso Abdominal/patologia , Abscesso/complicações , Abscesso/microbiologia , Abscesso/patologia , Abscesso/veterinária , Animais , Doença Crônica , Escherichia coli , Infecções por Escherichia coli/complicações , Infecções por Escherichia coli/patologia , Nefropatias/complicações , Nefropatias/microbiologia , Nefropatias/patologia , Masculino , Pielonefrite/complicações , Pielonefrite/patologia , Ultrassonografia/veterinária
4.
BMC Vet Res ; 13(1): 263, 2017 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-28830505

RESUMO

BACKGROUND: In goats, contagious caprine pleuropneumonia (CCPP) is a cause of major economic losses in Africa, Asia and in the Middle East. There is no information emphasising the importance of diagnostic ultrasound in goats with CCPP caused by Mycoplasma capricolum subsp. capripneumoniae (Mccp). This study was designed to describe the ultrasonographic findings in goats with CCPP caused by Mccp and to correlate ultrasonographic with post-mortem findings. To this end, 55 goats with CCPP were examined. Twenty-five healthy adult goats were used as a control group. RESULTS: Major clinical findings included harried, painful respiration, dyspnoea and mouth breathing. On ultrasonography, a liver-like echotexture was imaged in 13 goats. Upon post-mortem examination, all 13 goats exhibited unilateral pulmonary consolidation. Seven goats had a unilateral hypoechoic pleural effusion. At necropsy, the related lung was consolidated and the pleural fluid appeared turbid and greenish. Pleural abscessiation detected in five goats was confirmed post-mortem. Twenty-eight goats had a bright, fibrinous matrix extending over the chest wall containing numerous anechoic fluid pockets with medial displacement and compression of lung tissue. Echogenic tags imaged floating in the fluid were found upon post-mortem examination to be fibrin. In two goats, a consolidated right parenchyma was imaged together with hypoechoic pericardial effusions with echogenic tags covering the epicardium. At necropsy, the right lung was consolidated in three goats and fibrin threads were found covering the epicardium and pericardium. CONCLUSIONS: In goats with CCPP, the extension and the severity of the pulmonary changes could not be verified with clinical certainty in most cases, whereas this was possible most of the time with sonography, thus making the prognosis easier. Ultrasonographic examination of the pleurae and the lungs helped in the detection of various lesions.


Assuntos
Doenças das Cabras/diagnóstico por imagem , Mycoplasma capricolum , Pleuropneumonia Contagiosa/diagnóstico por imagem , Ultrassonografia/veterinária , Animais , Autopsia/veterinária , Feminino , Doenças das Cabras/parasitologia , Cabras , Pulmão/diagnóstico por imagem , Masculino , Miocárdio/ultraestrutura
5.
Theriogenology ; 89: 201-205, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-28043353

RESUMO

This study aimed to clarify the phenomenon of erectile dysfunction (ED) in male camels and monitor the associated changes in nitric oxide metabolite (NOM), cardiac troponin I (cTnI), and testosterone concentrations. A total 18 camels with ED and 10 controls were included in this study. The breeding history was recorded and a thorough breeding soundness examination was performed. Total nitrates and nitrites were determined in sera using the Griess assay. Serum cTnI and testosterone were assessed using ELISA. A complete blood count was also carried out. The results showed that 13/18 male camels with ED had no detectable pathologic lesions in the genital tract (ED-N), while 5/18 males showed pathology in the penis, prepuce, and testicles (ED-P). The ED-P group exhibited higher concentrations of NOMs (P = 0.003), white blood cells (P = 0.0001), and neutrophils (P = 0.001) than the ED-N and control groups. The ED-P and ED-N groups had higher concentrations of cTnI than the control group (P = 0.0001). Testosterone concentration did not differ among the groups. In conclusion, the ED in the camels was associated with a rise in cTnI, probably due to myositic damage. Most of the ED cases in the camels had apparently normal genital organs. In the cases of ED in male camels with detectable pathologic lesions on their genital organs, a rise in NOMs, white blood cells, and neutrophils was observed.


Assuntos
Camelus/fisiologia , Disfunção Erétil/veterinária , Óxido Nítrico/metabolismo , Testosterona/metabolismo , Troponina/metabolismo , Animais , Contagem de Células Sanguíneas/veterinária , Ensaio de Imunoadsorção Enzimática , Genitália Masculina/patologia , Genitália Masculina/fisiopatologia , Masculino
6.
Minerva Urol Nefrol ; 69(3): 262-270, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-27681660

RESUMO

BACKGROUND: Enough data about health related quality of life (HRQOL) after radical cystectomy (RC) and urinary diversion (UD) in women is still lacking. The objectives are to evaluate HRQOL in women after RC and orthotopic neobladder (ONB) versus ileal loop conduit (IC) and to assess the impact of urinary continence. METHODS: The study included 145 women who underwent RC and came for routine follow-up. HRQOL was assessed by two questionnaires (EORTC-QLQ-C30and FACT-Bl). ONB group was stratified to: totally continent, with nocturnal incontinence (NI) and patients in chronic urinary retention (CUR) and maintained on CIC. The orthotopic group (as a whole and its 3 subgroups) was compared to IC. RESULTS: ONB group included 22 continent women, 35 with NI and 27 in CUR and on CIC. There were no statistically significant differences between ONB and IC groups in all domains of the two questionnaires. However, continent women showed statistically significant better most of EORTC-QLQ-C30 scales and emotional well-being, functional well-being, bladder cancer subscale and FACT-Bl total Score (P˂0.05) than IC group. Similarly, women in CUR showed statistically significant better global health and physical functioning EORTC-QLQ-C30 scores (P values=0.0001, 0.01) and all domains of FACT-Bl. On the other hand, women with NI showed statistically significant lower values in all domains of the EORTC-QLQ-C30 and FACT-Bl than IC group. CONCLUSIONS: In women, HRQOL is better after ONB than IC as long as continence status is preserved. If incontinence is expected, IC may be a better option for UD.


Assuntos
Cistectomia/métodos , Enurese Noturna/fisiopatologia , Cistectomia/efeitos adversos , Feminino , Humanos , Pessoa de Meia-Idade , Qualidade de Vida , Resultado do Tratamento , Derivação Urinária/efeitos adversos , Derivação Urinária/métodos , Retenção Urinária/fisiopatologia
7.
Anim Reprod Sci ; 170: 149-56, 2016 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-27211280

RESUMO

The objectives of this study were to investigate the prevalence of dystocia in camel herds, its forms in primi- and multipara, the risks to fetus and dam, and the associated hematobiochemical changes. A total of 1890 calvings were surveyed for the prevalence of dystocia. Cases with dystocia (n=107) were examined for causes and treated with traction, fetotomy or Cesarean section. Logistic regression was performed to identify risk factors. The dependent variables were the fetal and maternal mortality, while the independent variables were parity, duration of dystocia, causes of dystocia, and method of treatment. Blood samples were collected from all dystocia camels and six controls for hematology and concentrations of serum amyloid A (SAA), haptoglobin (Hp), estradiol-17ß (E2), progesterone (P4), total protein, albumin, calcium, phosphorus, magnesium, blood urea nitrogen (BUN), creatinine and aspartate aminotransferase (AST). The overall prevalence of dystocia was 8.6%. Risk of dystocia was higher in camels managed in an intensive system than in those in a free system (Odds ratio=1.9, P=0.0003) and higher in primipara than in multipara (Odds ratio 1.7, P=0.005). Abnormal posture was the most important cause of dystocia (51.4%). Uterine torsion was the second most important cause (23.4%) and was mainly observed in multipara (P=0.0006). Dystocia was linked to high fetal mortality (87.9%). A significant relationship was found between fetal death and duration of dystocia (Odds ratio=8.04, P=0.005). The percentage of dam mortality was 17.8%. Significant associations were detected between dam mortality rate and the duration of dystocia (Odds ratio=4.74, P=0.03) and fetal viability (Odds ratio=5.82, P=0.02). Increasing duration of dystocia was associated with significant increases in SAA, Hp, BUN and AST, but with decreases in E2 (P<0.05). After a transient period of elevation, the white blood cell and neutrophil counts decreased (P<0.05). In conclusion, abnormal posture and uterine torsion were found to be the common causes of dystocia in dromedary camels, and fetal and maternal deaths were mainly associated with the duration of dystocia.


Assuntos
Camelus/cirurgia , Distocia/veterinária , Animais , Camelus/sangue , Cesárea/veterinária , Distocia/sangue , Distocia/patologia , Distocia/cirurgia , Feminino , Morte Fetal , Razão de Chances , Paridade , Gravidez , Fatores de Risco
8.
Arab J Urol ; 14(1): 1-6, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26966585

RESUMO

OBJECTIVE: To study the effect of sildenafil citrate on spontaneous passage of distal ureteric stones (DUS). PATIENTS AND METHODS: This was a randomised double-blinded placebo-controlled study of 100 patients with DUS. Inclusion criteria were: male, age 18-65 years, normal renal function, and a single radiopaque unilateral DUS of 5-10 mm. Patients were randomly allocated into two equal groups, one that received placebo and the other that received 50 mg sildenafil citrate once daily. Both investigators and patients were masked to the type of treatment. Patients self-administered the medication until spontaneous passage of the DUS. In patients where there was uncontrolled pain, fever, an increase in serum creatinine of >1.8 mg/dL, progressive hydronephrosis or no further progress after 4 weeks, a decision was taken for further treatment. RESULTS: In all, 47 and 49 patients were available for analysis in both the placebo and sildenafil citrate groups; respectively. Both groups were comparable for age and stone characteristics. Spontaneous expulsion occurred in 19 of 47 patients (40.4%) in the placebo group and in 33 of 49 (67.3%) in the sildenafil citrate group (P = 0.014). The mean time to stone expulsion was significantly shorter in the sildenafil citrate group (P < 0.001). A multivariable Cox proportional hazards model showed that receiving sildenafil citrate was the only independent factor that had a significant impact on stone passage with a hazard ratio of 2.7 (95% confidence interval 1.5-4.8; P < 0.001). CONCLUSION: Sildenafil citrate enhances spontaneous passage of 5-10 mm DUS.

9.
World J Urol ; 34(7): 963-8, 2016 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-26453222

RESUMO

PURPOSE: To compare the effectiveness of tamsulosin and solifenacin in relieving ureteral stents related symptoms. PATIENTS AND METHODS: A randomized controlled trial was conducted between January 2013 and July 2014. Inclusion criteria were patients aged 20-50 years who underwent temporary unilateral ureteral stent for drainage of calcular upper tract obstruction or after ureteroscopic lithotripsy. Patients with history of lower urinary tract symptoms before stent placement, stents that were fixed after open or laparoscopic procedures, and those who developed complications related to the primary procedure were not included. Eligible patients were randomly assigned to 1 of 3 groups using computer-generated random tables. Patients in group 1 received placebo, patients in group 2 received tamsulosin 0.4 mg once daily, and those in group 3 received solifenacin 5 mg once daily. Ureteral Stent Symptom Questionnaire (USSQ) was answered by all patients 1-2 weeks after stent placement. The primary outcome was the comparison of total score of USSQ between all groups. RESULTS: The study included 131 patients. All baseline characteristics (age, sex, side, indication, length, and duration of stent) were comparable for all groups. Total USSQ score was 61 in solifenacin group, 76 in tamsulosin group, and 83 in control group (P < 0.001). The total USSQ scores and all domains, except sexual index, were significantly better in solifenacin than in tamsulosin group (P < 0.05). CONCLUSION: The use of tamsulosin alone or solifenacin alone in patients with ureteral stents can improve the quality of life by decreasing ureteral stent-related symptoms. Solifenacin was better than tamsulosin. CLINICALTRIAL. GOV IDENTIFIER: NCT01880619.


Assuntos
Antagonistas Adrenérgicos alfa/uso terapêutico , Antagonistas Colinérgicos/uso terapêutico , Complicações Pós-Operatórias/tratamento farmacológico , Complicações Pós-Operatórias/etiologia , Succinato de Solifenacina/uso terapêutico , Stents/efeitos adversos , Sulfonamidas/uso terapêutico , Doenças Ureterais/tratamento farmacológico , Doenças Ureterais/etiologia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Tansulosina
10.
Arab J Urol ; 13(4): 277-81, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26609447

RESUMO

OBJECTIVE: To identify patient and stricture characteristics predicting failure after direct vision internal urethrotomy (DVIU) for single and short (<2 cm) bulbar urethral strictures. PATIENTS AND METHODS: We retrospectively analysed the records of adult patients who underwent DVIU between January 2002 and 2013. The patients' demographics and stricture characteristics were analysed. The primary outcome was procedure failure, defined as the need for regular self-dilatation (RSD), redo DVIU or substitution urethroplasty. Predictors of failure were analysed. RESULTS: In all, 430 adult patients with a mean (SD) age of 50 (15) years were included. The main causes of stricture were idiopathic followed by iatrogenic in 51.6% and 26.3% of patients, respectively. Most patients presented with obstructive lower urinary tract symptoms (68.9%) and strictures were proximal bulbar, i.e. just close to the external urethral sphincter, in 35.3%. The median (range) follow-up duration was 29 (3-132) months. In all, 250 (58.1%) patients did not require any further instrumentation, while RSD was maintained in 116 (27%) patients, including 28 (6.5%) who required a redo DVIU or urethroplasty. In 64 (6.5%) patients, a redo DVIU or urethroplasty was performed. On multivariate analysis, older age at presentation [odds ratio (OR) 1.017; P = 0.03], obesity (OR 1.664; P = 0.015), and idiopathic strictures (OR 3.107; P = 0.035) were independent predictors of failure after DVIU. CONCLUSION: The failure rate after DVIU accounted for 41.8% of our present cohort with older age at presentation, obesity, and idiopathic strictures independent predictors of failure after DVIU. This information is important in counselling patients before surgery.

11.
BMC Vet Res ; 10: 64, 2014 Mar 12.
Artigo em Inglês | MEDLINE | ID: mdl-24621180

RESUMO

BACKGROUND: The effect of digoxin administration on the serum concentration of the cardiac troponin I (cTnI) has not been reported to date in equidae. This study was therefore designed to evaluate the effect of digoxin on cardiac cell damage in donkeys (Equus asinus) as assessed by cTnI, acid-base and electrolyte balance and haematobiochemical profiles. Ten clinically healthy donkeys were given an IV infusion of digoxin at a dose of 14 µg/kg. Blood samples were collected from the donkeys up through 72 h post-injection. RESULTS: Three of the donkeys exhibited increased heart and respiratory rates post-injection. In the other seven animals, the heart and respiratory rates were lower 4 h post-injection. The serum digoxin concentration increased significantly at many time points after injection. The serum concentration of cTnI did not differ significantly between pre- and post-injection. An increase in blood pH was noted at 3 h after digoxin injection. There were also increases in PO2 and in oxygen saturation. Decreases in PCO2 at 2 to 48 h post-injection as well as a decrease in blood lactate at 4 h post-injection were observed. The serum concentration of glucose remained significantly elevated at all-time points after digoxin injection. CONCLUSIONS: It is concluded that administration of digoxin to healthy donkeys (14 µg/kg) did not result in elevations of serum cTnI concentration, signs of digoxin intoxication, ECG abnormalities and did not increase serum concentrations of blood urea nitrogen and creatinine.


Assuntos
Equilíbrio Ácido-Base/efeitos dos fármacos , Digoxina/farmacologia , Equidae/sangue , Troponina I/sangue , Equilíbrio Hidroeletrolítico/efeitos dos fármacos , Animais , Dióxido de Carbono/sangue , Cardiotônicos/farmacologia , Masculino , Miócitos Cardíacos/efeitos dos fármacos , Oxigênio/sangue
12.
Trop Anim Health Prod ; 46(1): 139-44, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-24002539

RESUMO

The aim of the present study was to evaluate the serum concentration of cardiac troponin I (cTnI) in camels with tick infestation as a marker of potential myocardial injury and its prognostication. The effects of acid-base and electrolyte balance and haematobiochemical profiles were also investigated. Twenty-three camels (Camelus dromedarius) with tick infestation and suffering from anorexia, incoordination of movement, unsteady gait, recumbency, opisthotonus, anaemia and reduced production were examined. Ticks were visible, deeply embedded in the skin over the whole body, especially under the neck and around the udder or testis. Of the camels, 15 recovered after treatment and 8 did not. Blood samples were collected from the diseased camels on the day of admission to our clinic. Blood samples were also collected from 12 healthy camels and were used as controls. The mean serum concentration of cTnI in the camels with tick infestation was 1.7 ± 1.6 ng/ml compared to 0.03 ± 0.02 ng/ml in the controls. The mean serum concentration of cTnI in those camels that recovered was 0.36 ± 0.53 ng/ml compared to 3.0 ± 1.1 ng/ml in the camels that did not. Venous blood gas alterations included an increase in partial pressure of carbon dioxide and decreases in partial pressure of oxygen and oxygen saturation. Haematological parameters involved decreases of red blood cells, haemoglobin and haematocrit and increases in the mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration. Biochemical parameters included significant elevations in the serum activity of aspartate aminotransferase, creatine kinase and alkaline phosphates. Other biochemical alterations observed were decreases in total protein and albumin and increases in globulin and glucose concentrations. In conclusion, the data of this study suggest the possibility of using cTnI as a biomarker for cardiac injury in camels with tick infestation and for the prognosis of the outcome in the treated animals. Generally, values above 1.0 ng/ml were considered bad prognostic indicators.


Assuntos
Equilíbrio Ácido-Base , Camelus/sangue , Camelus/parasitologia , Infestações por Carrapato/veterinária , Troponina I/sangue , Equilíbrio Hidroeletrolítico/fisiologia , Animais , Biomarcadores/sangue , Estudos de Casos e Controles , Feminino , Masculino , Valor Preditivo dos Testes , Infestações por Carrapato/sangue , Infestações por Carrapato/fisiopatologia , Resultado do Tratamento , Troponina I/metabolismo
13.
Arab J Urol ; 12(4): 256-61, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26019959

RESUMO

OBJECTIVE: To determine the use of the prostate specific antigen (PSA) level and digital rectal examination (DRE) findings to estimate the resected tissue weight (RTW) before transurethral resection of the prostate (TURP). PATIENTS AND METHODS: We retrospectively analysed 983 patients who underwent TURP between December 2006 and December 2012. The primary outcome was the RTW required for clinical improvement, and was not associated with re-intervention. Age, PSA level, body mass index (BMI) and DRE findings were correlated and modelled with the RTW. The DRE result was defined as DREa (small vs. large) or DREb (small vs. moderate vs. large) according to the surgeon's report. Equations to calculate RTW were developed and tested using receiver operating characteristic (ROC) curve analyses. RESULTS: There were significant correlations between PSA level (r = 0.4, P < 0.001) and RTW, whilst BMI and age showed weak correlations. The median (range) RTW was 45 (7-60) vs. 15 (6-60) g for small vs. large prostates (DREa) (P < 0.001), respectively. Similarly, the median (range) RTW was 11 (6-59) vs. 26.2 (6-60) vs. 42 (7-60) g in small vs. moderate vs. large prostates (DREb) (P < 0.001), respectively. Using PSA level and DREb (model 3) there was a significantly better ability to estimate RTW than using PSA and DREa (model 2) or PSA alone (model 1) based on ROC curve analyses. The equation developed by model 3 (RTW = 1.2 + (1.13 × PSA) + (DREb × 9.5)) had a sensitivity and specificity of 82% and 71% for estimating a RTW of >30 g, and 84% and 63% for estimating a RTW of >40 g, respectively. CONCLUSIONS: The PSA level and DRE findings can be used to predict the RTW before TURP.

14.
Arab J Urol ; 12(4): 290-3, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26019964

RESUMO

OBJECTIVE: To validate the Arabic version of the Ureteral Stent Symptoms Questionnaire (USSQ). PATIENTS AND METHODS: The English version of the USSQ was translated into Arabic using a multi-step process by three urologists and two independent translators. The Arabic version was validated by asking 37 patients with temporary unilateral ureteric stents to complete the questionnaire at 2 weeks after stent insertion. The second group included 53 healthy individuals who agreed to complete the Arabic version of the questionnaire. The reliability of the Arabic version was evaluated for internal consistency using Cronbach's α test. Domain structures were examined by interdomain (section) associations using Spearman's correlation coefficient (r). The discrimination validity was evaluated by comparing the scores of patients with those of healthy individuals, using the Mann-Whitney test. RESULTS: Internal consistency was high for the sexual index and intermediate for urinary, pain and general health indices. There were good correlations of urinary symptoms with body pain (r = 0.596) and general health (r = 0.690). There was also a good correlation between body pain and general health (r = 0.681). For discrimination validity, there were significant changes in all domain scores when comparing patients with ureteric stents and healthy individuals (P < 0.001). CONCLUSION: The Arabic version of the USSQ is a reliable and valid instrument that can be used to evaluate symptoms and health-related quality of life in Arabic patients with ureteric stents.

15.
J Vet Cardiol ; 15(4): 253-61, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24252809

RESUMO

OBJECTIVE: To determine valvular thickness in healthy cows, cows with bacterial endocarditis, and cows with various cardiorespiratory diseases. ANIMALS: 40 healthy Holstein adult cows (CONTROL), 6 adult cows with confirmed bacterial endocarditis (BE), and 10 cows with other cardiorespiratory disorders (NONBE). METHODS: Prospective study using right transthoracic echocardiographic examination in CONTROL, BE and NONBE cows. The valvular thicknesses of all cows were assessed in four different locations for all cardiac valves, and the maximal value was used for further analysis. RESULTS: The mean [±standard deviation (SD)] maximal thicknesses of the tricuspid, mitral, aortic, and pulmonary valves in the CONTROL group were 0.69 ± 0.10 cm, 0.85 ± 0.21 cm, 0.72 ± 0.17 cm, and 0.58 ± 0.12 cm, respectively. The maximal valvular thicknesses were less than 0.97 cm for the tricuspid, less than 0.91 cm for pulmonary, less than 1.05 cm for the aortic, and less than 1.28 cm for the mitral. In BE cows, the maximal valvular thickness of affected valves (median: 4.22 cm; range: 2.52-6.97 cm) and non affected valves (median: 0.75 cm; range: 0.45-1.52 cm) were significantly different (P = 0.0004). The maximal valvular thicknesses of the NONBE valves as well as the unaffected valves in the BE group were not significantly different compared to the CONTROL group valves. CONCLUSIONS: Using the mean ± 2SD formula for each valve in healthy cows, a thickness of tricuspid, mitral, aortic or pulmonary valves greater than 0.85 cm, 1.27 cm, 1.06 cm or 0.82 cm respectively should raise the suspicion of valvular bacterial endocarditis.


Assuntos
Doenças dos Bovinos/patologia , Ecocardiografia/veterinária , Endocardite Bacteriana/veterinária , Valvas Cardíacas/anatomia & histologia , Valvas Cardíacas/patologia , Animais , Bovinos , Endocardite Bacteriana/patologia , Feminino
16.
Acta Vet Hung ; 61(3): 309-18, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23921343

RESUMO

This study describes ultrasonography of the lungs and pleura in healthy camels (Camelus dromedarius). The different layers of the thoracic wall appeared as narrow bands of variable echogenicity. Reverberation artefacts appeared as lines of variable echogenicity that ran parallel to the pulmonary surface medial to the pleura. Because of its air content, the pulmonary parenchyma was not visualised in all camels. On the right side, the pulmonary surface was seen in the 5th through the 10th intercostal space (ICS). In addition, it was imaged in the 11th ICS in 20 camels and in the 4th ICS in three camels. The dimension of the ventral lung border was largest at the 4th ICS and smallest at the 11th ICS. The echogenic line on the surface of the lung, consisting of the costal and the parietal pleurae, was 1 to 4 mm thick. The left pulmonary surface and pleura were imaged with approximately the same frequencies as the right side. At this side, only the pulmonary surface and pleura were imaged in 15 camels in the 11th ICS. In conclusion, ultrasonography of the lungs and pleura provides information that can be used as a reference when examining camels suspected to have respiratory diseases.


Assuntos
Camelus , Pleura , Animais , Pulmão
17.
Acta Vet Hung ; 61(4): 442-53, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23974939

RESUMO

This study was designed to establish serum cardiac troponin I (cTnI) concentrations in healthy newborn goat kids and in those with cardiac nutritional muscular dystrophy (NMD). Thirty-five single full-term newborn goat kids (20 males and 15 females; age: 6.1 ± 3.5 h; weight 3.4 ± 0.68 kg), together with their respective mothers (Group 1; G1) were enrolled consecutively. Thirty-one goat kids (age: 9.5 ± 4.3 days) with NMD, together with 20 control goat kids (age: 7.8 ± 4.3 days) were also included in this study (Group 2; G2). Blood samples were collected from G1 within 12 h of birth and from G2 on admission. Serum samples were collected and analysed for cTnI. In G1, the mean serum concentration of cTnI in goat kids was 0.290 ± 0.37 ng/mL, with no statistically significant difference between male and female kids (P = 0.61). The mean cTnI concentration in the does was 0.017 ± 0.04, ng/mL. Serum values of cTnI in the goat kids and in their respective mothers differed significantly (P = 0.0001). In G2, the mean cTnI concentration was 0.02 ± 0.05 ng/mL in the control and 11.18 ± 20.07 ng/mL in the diseased goat kids, with a statistically significant difference between diseased and control goat kids (P = 0.017). Serum concentrations of cTnI are higher in goat kids than in their respective mothers. In conclusion, the cTnI assay appears to be a sensitive and specific marker for myocardial injury in goat kids.


Assuntos
Cabras , Troponina I , Animais , Biomarcadores , Distrofias Musculares , Parto , Troponina I/sangue
18.
J Vet Cardiol ; 15(1): 15-22, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23434241

RESUMO

OBJECTIVES: Little is known about cardiac biomarkers in camels despite their extensive use as draft animals. This study was designed to establish reference ranges for the cardiac biomarkers cardiac troponin I (cTnI) and creatine kinase myocardial b fraction (CK-MB) in healthy camels and to investigate their changes in response to road transportation. ANIMALS: Twenty-five healthy camels transported for a 5 h round-trip journey. METHODS: None of the camels had evidence of cardiac abnormalities on cardiac auscultation, echocardiography or electrocardiography. Three blood samples were obtained from each camel: 24 h before transportation (T0), within 2 h after unloading (T1) and 24 h after transportation (T2). RESULTS: The mean cTnI concentration in the camels was 0.032 ± 0.023 ng/mL. All the camels had resting cTnI concentrations of <0.08 ng/mL. At T1, the cTnI concentration was significantly higher (P < 0.001) in all 25 camels compared to values at T0. The CK-MB concentration in the camels was 0.19 ± 0.05 ng/mL. All the camels had resting CK-MB concentrations of <0.33 ng/mL. At T1, the CK-MB concentration was higher in 3/25 camels compared to values at both T0 and T2. Concerning the hematobiochemical variables, significant increases were detected at T1 in total white blood cells, total protein, globulin, magnesium and phosphorus. Cardiac troponin I, CK-MB and all the hematobiochemical parameters had returned to their pre-transport values at T2. CONCLUSIONS: 5 h road transportation might have transient adverse effects on the cardiac muscle of healthy camels.


Assuntos
Biomarcadores/sangue , Camelus/sangue , Miocárdio/metabolismo , Estresse Fisiológico/fisiologia , Transportes , Animais , Camelus/fisiologia , Feminino , Troponina I/genética , Troponina I/metabolismo
19.
Vet J ; 197(3): 900-2, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23434264

RESUMO

The objective of this study was to investigate the effect of racing on the serum concentrations of cardiac troponin I (cTnI) and creatine kinase myocardial band (CK-MB) in 32 racing greyhounds. Blood samples were collected 24h prior to a 7 km race (T0), within 2h of completion of the race (T1), and 24h post-race (T2). Blood samples were also collected from 20 non-racing greyhounds. The median cTnI concentration in the racing greyhounds was not significantly different from that in the non-racing greyhounds (0.045 ng/mL). Before racing, the median cTnI concentration in the racing greyhounds was 0.050 ng/mL. Following the 7 km race, 31/32 greyhounds showed increases in cTnI concentrations which were significantly higher than the pre-race concentrations (P<0.0001). cTnI concentrations dropped back 24h post-race to values not significantly different from the pre-race concentrations. Following the race, 5/32 greyhounds showed mild increases in CK-MB concentrations but these were not significantly different from the pre-race values. These findings could be of importance when evaluating greyhounds with suspected cardiac disease that have recently performed hard exercise.


Assuntos
Creatina Quinase/sangue , Cães/sangue , Cães/fisiologia , Corrida , Esportes , Troponina I/sangue , Animais , Biomarcadores , Creatina Quinase/metabolismo , Condicionamento Físico Animal , Troponina I/metabolismo
20.
Vet Res Commun ; 37(2): 139-44, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23435840

RESUMO

This study was designed to investigate the effect of racing on the serum concentrations of cardiac troponin I (cTnI) and creatine kinase myocardial (CK-MB) in healthy racing camels (Camelus dromedarius). Twenty-three racing camels scheduled for a 5 km race were investigated in this study. From each camel, 3 blood samples were collected: 24 h before racing (T0), within 2 h after the race (T1) and 24 h post-race (T2). Following the 5 km race, 91.3 % of the racing camels had increases in serum cTnI concentrations, while concentrations remained unchanged in 8.7 %. The cTnI concentration (median 0.06 ng/mL; range, 0.03-0.15 ng/mL) was significantly higher (P < 0.001) than the pre-race values (median 0.04 ng/mL; range, 0.01-0.07 ng/mL). Twenty-four hours post-race, the cTnI concentrations had returned very nearly to their pre-race values (median 0.04 ng/mL; range, 0.00-0.09 ng/mL) and were not significantly different (P = 0.35) from the pre-race values. Following the 5 km race, increases in CK-MB mass were seen in 17.4 % of the camels, with no changes in 4.3 % and decreases in 78.3 %. The CK-MB mass (median 0.41 ng/mL; range, 0.19-0.60 ng/mL) did not differ significantly (P = 0.84) when compared to the pre-race values (median 0.42 ng/mL; range, 0.32-0.55 ng/mL). Twenty-four hours post-race, the CK-MB mass concentrations (median 0.41 ng/mL; range, 0.15-0.55 ng/mL) did not differ significantly (P > 0.05) compared to pre-race or immediate post-race values. Resting cTnI concentrations in the racing camels were initially low, but increased above the baseline level in most of the camels immediately after racing, and returned to pre-race values within the 24-h post-race period. CK-MB is a less sensitive biomarker for myocardial activity as compared with cTnI. These findings could be of importance when evaluating racing camels with suspected cardiac disease after recent hard exercise.


Assuntos
Camelus/metabolismo , Creatina Quinase/sangue , Miocárdio/enzimologia , Corrida/fisiologia , Troponina I/sangue , Animais , Biomarcadores/sangue , Camelus/sangue , Feminino , Estatísticas não Paramétricas
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA