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1.
Lasers Surg Med ; 52(4): 323-332, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31347193

RESUMO

BACKGROUND AND OBJECTIVES: To assess the effectiveness of ultrasound (US)-guided laser ablation of benign thyroid nodules (TNs) under different amounts of applied energy. STUDY DESIGN/MATERIALS AND METHODS: Thirty-four euthyroid patients with 5-18 ml TNs were enrolled: 21 (laser ablation) and 13 (clinical follow up) patients with a mean age of 56.2 ± 12.0 and 54.7 ± 14.7 years, respectively. The laser ablation protocol used a 1.064 mm wavelength diode laser source; 3.5 W output power; 1,100-1,500 J and 5-8 min/illumination; and one or two fibers/session. Clinical, laboratory, and US data were obtained immediately before treatment and at 6 and 12 months follow-up and were analyzed by Student's t test and Fisher's exact test. Low- and high-energy subgroups were subsequently defined, and the receiver operating characteristic (ROC) curves were calculated. RESULTS: Laser ablation follow-up showed an overall nodule volume reduction of more than 50%; improvement of symptoms and cosmetic complaints (P = 0.001); and stable laboratory data compared with the baseline and control groups. Minor complications were 9.5% ( n = 2). One or two fibers/session resulted in a similar nodule volume reduction among 10-18 ml nodules. Analysis of the applied energy suggested a 398.8 J/ml inferior cutoff (ROC curve: 0.889 sensitivity; 0.545 specificity) for the high-energy subgroup ( n = 14, mean 599.9 ± 136.5 J/ml) to reduce the nodule volume over time (-55.1% vs. -58.4%, P = 0.55). The low-energy subgroup ( n = 7, mean 240.2 ± 74.6 J/ml) did not show a persistent volume reduction ( P < 0.05) from the 6- to 12-month follow-ups (-56.6% vs. -53.7%). CONCLUSIONS: Laser ablation of benign TNs achieved technique efficacy at 12 months posttreatment, with clinical improvement and few minor side effects. A single fiber in a single session with a high deployed energy (>398.8 J/ml) may be associated with improved results, a finding to be confirmed with a larger series. Lasers Surg. Med. © 2019 Wiley Periodicals, Inc.

2.
Clin Nurs Res ; 29(4): 260-267, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-30338694

RESUMO

The purpose of this study was to compare the effect of ear protectors on the sleep of preterm newborns during the "quiet" times in intermediate care nursery. This was a clinical, randomized, controlled crossover study conducted in two neonatal units in São Paulo, Brazil. The sample consisted of preterm infants who met the inclusion and exclusion criteria for the study. Polysomnography and unstructured observation were used for data collection. Twenty-four preterm infants with a mean gestational age of 33.2 weeks and current weight of 1.747 g were analyzed. There was no significant difference in the total sleep time of preterm infants with and without the use of ear protectors. Newborns with lower gestational age showed a significant reduction in total sleep time with the use of ear protectors (p < .05). The use of ear protection did not increase the total sleep time for preterm infants.

3.
Rev Bras Enferm ; 72(suppl 3): 274-281, 2019 Dec.
Artigo em Inglês, Português | MEDLINE | ID: mdl-31851264

RESUMO

OBJECTIVE: To conduct a cross-cultural adaptation of the Preterm Parenting & Self-Efficacy Checklist to the Brazilian Portuguese. METHOD: A methodological study was carried out with 51 parents of premature infants. Data analysis was based on psychometric and inferential statistical analyses. RESULTS: The instrument content validation by experts obtained excellent agreement (97%) and the semantic analysis by the target population showed good understanding of the terms and ease of use. In test-retest, most participants were female (64.7%); and parents with higher education (47.1%). The instrument showed stability over time, with good internal consistency (α = 0.84). Four factors were generated in the subscales parenting self-efficacy, importance of tasks and self-perceived parental competence (67.0% to 74.2% of the variance). CONCLUSION: The properties of the Preterm Parenting & Self-Efficacy Checklist - Brazilian Version were maintained, which is a reliable indicator to evaluate the hospital discharge of premature infants.


Assuntos
Lista de Checagem/normas , Recém-Nascido Prematuro/psicologia , Poder Familiar/psicologia , Psicometria/normas , Autoeficácia , Adolescente , Adulto , Brasil , Lista de Checagem/métodos , Assistência à Saúde Culturalmente Competente , Feminino , Humanos , Recém-Nascido , Masculino , Psicometria/instrumentação , Psicometria/métodos , Reprodutibilidade dos Testes , Inquéritos e Questionários
4.
Rev. bras. enferm ; 72(supl.3): 274-281, 2019. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1057713

RESUMO

ABSTRACT Objective: To conduct a cross-cultural adaptation of the Preterm Parenting & Self-Efficacy Checklist to the Brazilian Portuguese. Method: A methodological study was carried out with 51 parents of premature infants. Data analysis was based on psychometric and inferential statistical analyses. Results: The instrument content validation by experts obtained excellent agreement (97%) and the semantic analysis by the target population showed good understanding of the terms and ease of use. In test-retest, most participants were female (64.7%); and parents with higher education (47.1%). The instrument showed stability over time, with good internal consistency (α = 0.84). Four factors were generated in the subscales parenting self-efficacy, importance of tasks and self-perceived parental competence (67.0% to 74.2% of the variance). Conclusion: The properties of the Preterm Parenting & Self-Efficacy Checklist - Brazilian Version were maintained, which is a reliable indicator to evaluate the hospital discharge of premature infants.


RESUMEN Objetivo: Realizar la adaptación transcultural de Preterm Parenting & Self-Efficacy Checklist para el portugués de Brasil. Método: Estudio metodológico, en el cual participaron 51 padres de recién nacidos prematuros. En el análisis de datos se utilizaron la psicometría y la estadística inferencial. Resultados: La validación de contenido del instrumento por los expertos obtuvo una concordancia excelente (97%), y el análisis semántico con la población demostró comprensión de los términos y facilidad en su utilización. En el test-retest, hubo la mayoría de participantes del sexo femenino (64,7%); y de padres con enseñanza superior (47,1%). El instrumento fue estable a lo largo del tiempo, presentando una buena consistencia interna (α = 0.84). Se generaron cuatro factores en las subescalas: autoeficacia parental; importancia de las tareas; y competencia parental autopercibida (del 67,0% al 74,2% de la varianza). Conclusión: Las propiedades de Preterm Parenting & Self-Efficacy Checklist -versión brasileña- se mantuvieron, lo que configura como un indicador fiable de evaluación del alta hospitalaria del prematuro.


RESUMO Objetivo: Realizar a adaptação transcultural do Preterm Parenting & Self-Efficacy Checklist para o português brasileiro. Método: Estudo metodológico, realizado com 51 pais de recém-nascidos prematuros. A análise dos dados utilizou-se da psicometria e da estatística inferencial. Resultados: A validação de conteúdo do instrumento pelos especialistas obteve concordância excelente (97%), e a análise semântica com a população-alvo demonstrou compreensão dos termos e facilidade na sua utilização. No teste-reteste, houve maioria de participantes do sexo feminino (64,7%) e de pais com ensino superior (47,1%). O instrumento apresentou estabilidade ao longo do tempo, com boa consistência interna (α = 0.84). Quatro fatores foram gerados nas subescalas "autoeficácia parental", "importância das tarefas" e "competência parental autopercebida" (67,0% a 74,2% da variância). Conclusão: Houve a manutenção das propriedades do Preterm Parenting & Self-Efficacy Checklist - Versão Brasileira, que se configura como um indicador confiável para avaliar a alta hospitalar do prematuro.

5.
Rev Lat Am Enfermagem ; 26: e3084, 2018 Nov 29.
Artigo em Inglês, Português, Espanhol | MEDLINE | ID: mdl-30517575

RESUMO

OBJECTIVE: to compare two compression times of the radial artery after coronary angiography with customized compressive dressing regarding the occurrence of hemostasis and vascular complications. METHOD: a randomized clinical study was carried out in patients undergoing elective transradial coronary angiography in two study groups: (G30), whose compressive dressing was maintained for 30 minutes, and (G60), whose compressive dressing was maintained for 60 minutes, both until the first evaluation of hemostasis. Variables related to patients, procedure, occurrence of hemostasis, and vascular complications were analyzed. Patency of the radial artery was assessed with Doppler vascular ultrasonography, immediately after removing the compressive dressing and 30 days after the procedure. RESULTS: the sample consisted of 152 patients in G30 and 151 in G60. Hemostasis was evidenced in the first evaluation in 76.3% of G30 patients and 84.2% of G60 patients (p = 0.063). There were 91 immediate complications, being 53 hematomas and 38 occlusions of the radial artery. We identified 18 late occlusions, 7 (5.5%) in G30 and 11 (8.2%) in G60. CONCLUSION: the different compression times of the radial artery after coronary angiography did not significantly influence the occurrence of hemostasis and vascular complications. Brazilian Registry of Clinical Trials (Rebec): RBR-7VJYMJ.


Assuntos
Bandagens/normas , Cateterismo Cardíaco/efeitos adversos , Angiografia Coronária/efeitos adversos , Hemostasia/fisiologia , Artéria Radial/fisiopatologia , Doenças Vasculares/etiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Intervenção Coronária Percutânea/efeitos adversos , Doenças Vasculares Periféricas , Punções , Fluxo Sanguíneo Regional , Fatores de Tempo
6.
Adv Neonatal Care ; 18(5): 393-399, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30239405

RESUMO

BACKGROUND: Peak sound levels during sleep can compromise the development of hospitalized infants. Quiet time is a strategy implemented in neonatal units to promote the sleeping of neonates by reducing noise levels, luminosity, and handling during particular periods of the day. PURPOSE: To determine the impact of quiet time on reducing sound levels and increasing total sleep time. METHODS: This longitudinal study was conducted at a neonatal intermediate care unit with a convenience sample of 12 premature infants. Four times per day, 60-minute quiet times were provided in the neonatal unit. Sleep-awake states and sound levels were evaluated during quiet times as well as 60 minutes before and afterward. Polysomnography was used for sleep-awake state assessment, and a noise dosimeter was used to check sound levels every 24 hours. RESULTS: The preterm infants had a corrected gestational age of 35.0 ± 1.5 weeks and weighed 1606.0 ± 317.8 g. Total sleep time was highest during quiet time (P = .005). Premature infants remained awake for longer following quiet times (P = .005). There was also a reduction in sound level during quiet times compared with the other time frames (P = .006). No statistically significant relationship was found between total sleep time and sound levels more than 24 hours. IMPLICATIONS FOR PRACTICE: Quiet time is a nursing intervention that should be implemented in all neonatal units. IMPLICATIONS FOR RESEARCH: Future research should use a greater sample size and other factors that influence sleep should be further investigated.


Assuntos
Recém-Nascido Prematuro/fisiologia , Ruído , Sono/fisiologia , Vigília/fisiologia , Brasil , Hospitais Universitários , Humanos , Recém-Nascido , Estudos Longitudinais , Polissonografia
7.
Rev Bras Enferm ; 71(suppl 3): 1358-1365, 2018.
Artigo em Inglês, Português | MEDLINE | ID: mdl-29972535

RESUMO

OBJECTIVE: Analyze the influence of ear protectors on the baseline levels of salivary cortisol and response and total sleep time of preterm neonates during two periods of environmental management of a neonatal intermediate care unit. METHOD: A clinical, randomized, controlled and crossover study conducted with 12 preterm neonates. The use of ear protectors was randomized in two periods. Sleep evaluation was performed using one Alice 5 Polysomnography System and unstructured observation. RESULTS: No significant difference was observed between the baseline levels of salivary cortisol and response in preterm neonates from the control and experimental groups, and no statistical significance was observed between the total sleep time of both groups. No relationship was observed between the baseline levels of cortisol and response and total sleep time. CONCLUSION: Ear protectors in preterm neonates did not influence the salivary cortisol level and total sleep time in the studied periods.


Assuntos
Hidrocortisona/análise , Recém-Nascido Prematuro/metabolismo , Saliva/química , Sono/fisiologia , Estudos Cross-Over , Feminino , Humanos , Recém-Nascido , Masculino
8.
Virus Res ; 251: 22-33, 2018 06 02.
Artigo em Inglês | MEDLINE | ID: mdl-29730308

RESUMO

Porcine circovirus 2 (PCV2) is an icosahedral, non-enveloped, and single-stranded circular DNA virus that belongs to the family Circoviridae, genus Circovirus, and is responsible for a complex of different diseases defined as porcine circovirus diseases (PCVDs). These diseases - including postweaning multisystemic wasting syndrome (PMWS), enteric disease, respiratory disease, porcine dermatitis and nephropathy syndrome (PDNS), and reproductive failure - are responsible for large economic losses in the pig industry. After serial passages in swine testicle (ST) cells of a wild-type virus isolated from an animal with PMWS, we identified three PCV2b viruses with capsid protein (known as Cap protein) cumulative mutations, including two novel mutants. The mutant viruses were introduced into new ST cell cultures for reisolation and showed, in comparison to the wild-type PCV2b, remarkable viral replication efficiency (> 1011 DNA copies/ml) and cell death via necrosis, which were clearly related to the accretion of capsid protein mutations. The analysis of a Cap protein/capsid model showed that the mutated residues were located in solvent-accessible positions on the external PCV2b surface. Additionally, the mutated residues were found in linear epitopes and participated in pockets on the capsid surface, indicating that these residues could also be involved in antibody recognition. Taking into account the likely natural emergence of PCV2b variants, it is possible to consider that the results of this work increase knowledge of Circovirus biology and could help to prevent future serious cases of vaccine failure that could lead to heavy losses to the swine industry.


Assuntos
Proteínas do Capsídeo/genética , Infecções por Circoviridae/veterinária , Circovirus/genética , Circovirus/patogenicidade , Efeito Citopatogênico Viral , Proteínas Mutantes/genética , Animais , Proteínas do Capsídeo/metabolismo , Células Cultivadas , Infecções por Circoviridae/patologia , Infecções por Circoviridae/virologia , Circovirus/crescimento & desenvolvimento , Circovirus/ultraestrutura , Modelos Biológicos , Modelos Moleculares , Proteínas Mutantes/metabolismo , Inoculações Seriadas , Suínos , Doenças dos Suínos/patologia , Doenças dos Suínos/virologia
9.
Rev. latinoam. enferm. (Online) ; 26: e3084, 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-978615

RESUMO

Objective to compare two compression times of the radial artery after coronary angiography with customized compressive dressing regarding the occurrence of hemostasis and vascular complications. Method a randomized clinical study was carried out in patients undergoing elective transradial coronary angiography in two study groups: (G30), whose compressive dressing was maintained for 30 minutes, and (G60), whose compressive dressing was maintained for 60 minutes, both until the first evaluation of hemostasis. Variables related to patients, procedure, occurrence of hemostasis, and vascular complications were analyzed. Patency of the radial artery was assessed with Doppler vascular ultrasonography, immediately after removing the compressive dressing and 30 days after the procedure. Results the sample consisted of 152 patients in G30 and 151 in G60. Hemostasis was evidenced in the first evaluation in 76.3% of G30 patients and 84.2% of G60 patients (p = 0.063). There were 91 immediate complications, being 53 hematomas and 38 occlusions of the radial artery. We identified 18 late occlusions, 7 (5.5%) in G30 and 11 (8.2%) in G60. Conclusion the different compression times of the radial artery after coronary angiography did not significantly influence the occurrence of hemostasis and vascular complications. Brazilian Registry of Clinical Trials (Rebec): RBR-7VJYMJ.


Objetivo comparar dois tempos de compressão da artéria radial pós-cinecoronariografia com curativo compressivo customizado, quanto à ocorrência de hemostasia e de complicações vasculares. Método estudo clínico randomizado realizado em pacientes submetidos a cinecoronariografia eletiva pelo acesso transradial, alocados em dois grupos de estudo: G30, cujo curativo compressivo foi mantido por 30 minutos, e G60, no qual o curativo foi mantido por 60 minutos, ambos até a primeira avaliação de hemostasia. Foram avaliadas variáveis relativas aos pacientes, procedimento, ocorrência de hemostasia e complicações vasculares. A patência da artéria radial foi avaliada com ultrassonografia vascular com Doppler, imediatamente após a retirada da compressão e após 30 dias do procedimento. Resultados a amostra foi composta de 152 pacientes no G30 e 151 no G60. A hemostasia foi evidenciada na primeira avaliação em 76,3% dos pacientes do G30 e em 84,2% do G60 (p=0,063). Ocorreram 91 complicações imediatas, sendo 53 hematomas e 38 oclusões da artéria radial. Foram identificadas 18 oclusões tardias, sendo 7 (5,5%) no G30 e 11 (8,2%) no G60. Conclusão os diferentes tempos de compressão da artéria radial, após cinecoronariografia, não influenciaram significativamente a ocorrência de hemostasia e complicações vasculares. Registro Brasileiro de Ensaios Clínicos (Rebec): RBR-7VJYMJ.


Objetivo comparar dos tiempos de compresión de la arteria radial, después de cinecoronariografía con curativo compresivo personalizado, referido a la ocurrencia de hemostasia y de complicaciones vasculares. Método estudio clínico aleatorizado realizado en pacientes sometidos a cinecoronariografía electiva por acceso transradial, asignados en dos grupos de estudio: (G30) cuyo curativo compresivo fue mantenido por 30 minutos y (G60) en el cual el curativo fue mantenido por 60 minutos; ambos hasta la primera evaluación de hemostasia. Fueron evaluadas variables relativas a: pacientes, procedimiento, ocurrencia de hemostasia y complicaciones vasculares. La capacidad de mantener desobstruida la arteria radial fue evaluada con ultrasonografia vascular con Doppler, inmediatamente después de la retirada de la compresión y después de 30 días del procedimiento. Resultados la muestra estuvo compuesta por 152 pacientes en el G30 y 151 en el G60. La hemostasia fue evidenciada en la primera evaluación en 76,3% de los pacientes del G30 y en 84,2% del G60 (p=0,063). Ocurrieron 91 complicaciones inmediatas, siendo 53 hematomas y 38 oclusiones de la arteria radial. Fueron identificadas 18 oclusiones tardías, siendo 7(5,5%%) en el G30 y 11(8,2%) en el G60. Conclusión los diferentes tiempos de compresión de la arteria radial después de cinecoronariografía no influenciaron significativamente la ocurrencia de hemostasia y complicaciones vasculares. Registro Brasileño de Ensayos Clínicos (Rebec): RBR-7VJYMJ.


Assuntos
Humanos , Masculino , Feminino , Doenças Vasculares/fisiopatologia , Artéria Radial/fisiopatologia , Intervenção Coronária Percutânea/efeitos adversos , Fluxo Sanguíneo Regional/fisiologia , Doenças Vasculares Periféricas
10.
Rev. bras. enferm ; 71(supl.3): 1358-1365, 2018. tab
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-958737

RESUMO

ABSTRACT Objective: Analyze the influence of ear protectors on the baseline levels of salivary cortisol and response and total sleep time of preterm neonates during two periods of environmental management of a neonatal intermediate care unit. Method: A clinical, randomized, controlled and crossover study conducted with 12 preterm neonates. The use of ear protectors was randomized in two periods. Sleep evaluation was performed using one Alice 5 Polysomnography System and unstructured observation. Results: No significant difference was observed between the baseline levels of salivary cortisol and response in preterm neonates from the control and experimental groups, and no statistical significance was observed between the total sleep time of both groups. No relationship was observed between the baseline levels of cortisol and response and total sleep time. Conclusion: Ear protectors in preterm neonates did not influence the salivary cortisol level and total sleep time in the studied periods.


RESUMEN Objetivo: Certificar la influencia del uso de protectores auriculares en los niveles de cortisol salival basal y la respuesta y en el tiempo total de sueño de prematuros durante dos períodos de manejo del ambiente de una unidad de cuidado intermedio neonatal. Método: Ensayo clínico, aleatorio, controlado y cruzado conducido en 12 prematuros. El uso de protectores auriculares ha sido aleatorio en dos períodos. La evaluación del sueño ha sido realizada por medio del aparato de polisomnografía Alice 5 y de la observación no estructurada. Resultados: No ha habido diferencia significante entre los niveles de cortisol salival basal y la respuesta en los prematuros de los grupos control y experimental, no habiendo también significancia estadística entre el tiempo total de sueño de los dos grupos. No ha sido observada la relación entre los niveles de cortisol basal y la respuesta y el tiempo total de sueño. Conclusión: Los protectores auriculares en los prematuros no han influenciado el nivel de cortisol salival y el tiempo total de sueño en los períodos estudiados.


RESUMO Objetivo: Verificar a influência do uso de protetores auriculares nos níveis de cortisol salivar basal e resposta e no tempo total de sono de prematuros durante dois períodos de manejo do ambiente de uma unidade de cuidado intermediário neonatal. Método: Ensaio clínico, randomizado, controlado e cruzado conduzido em 12 prematuros. O uso de protetores auriculares foi randomizado em dois períodos. A avaliação do sono foi realizada por meio do polissonígrafo Alice 5 e da observação não estruturada. Resultados: Não houve diferença significante entre os níveis de cortisol salivar basal e resposta nos prematuros dos grupos controle e experimental, não havendo também significância estatística entre o tempo total de sono dos dois grupos. Não foi observada relação entre os níveis de cortisol basal e resposta e o tempo total de sono. Conclusão: Os protetores auriculares nos prematuros não influenciaram o nível de cortisol salivar e o tempo total de sono nos períodos estudados.

11.
Acta Paul. Enferm. (Online) ; 30(5): 489-496, Set.-Out. 2017. tab
Artigo em Português | LILACS-Express | LILACS, BDENF - Enfermagem | ID: biblio-885881

RESUMO

Resumo Objetivo: Identificar os tipos das manipulações realizadas em recém-nascidos prematuros e avaliar a influência sobre os tempos totais de sono, vigília e as variáveis objetivas do sono. Métodos: Estudo observacional e de correlação realizado em uma unidade neonatal de hospital universitário. A amostra foi constituída por 12 recém-nascidos prematuros que atenderam aos critérios de inclusão e exclusão estabelecidos para o estudo. Os dados foram coletados no período de março de 2013 à abril de 2014 e obtidos por meio do polissonígrafo, filmagem e observação durante 24 horas, ininterruptas. Utilizou-se a estatística descritiva, teste de Friedman, correlação de Pearson e regressão linear, com valores significantes p<0,05. Resultados: Os prematuros estudados eram predominantemente tardios, do sexo feminino, com baixo peso ao nascer e idade cronológica média de 14 dias. Os neonatos foram manipulados em média 176,4(±37,9) vezes durante as 24 horas, sendo que 58% das manipulações foram para monitoramento. A proporção do tempo total de sono foi 57,2% em 24 horas. Não houve correlação estatisticamente significante entre as frequências e os tempos de duração das manipulações diretas e do ambiente com o sono dos RNPT em 24 horas. A forma única apresentou correlação fortemente positiva com a vigília. Conclusão: As manipulações relacionaram-se ao monitoramento, terapêutica/diagnóstica e cuidados de higiene e conforto, com prevalência das manipulações diretas e únicas, não sendo identificada influência estatisticamente significante sobre as variáveis objetivas do sono, com exceção das manipulações únicas que apresentaram correlação com o tempo de vigília.


Abstract Objective: Identify the types of handling procedures performed on preterm infants and assess their influence on total sleep time, wake time and the objective sleep variables. Methods: Observational and correlational study conducted in the neonatal unit of a teaching hospital. The sample was made up of 12 preterm infants who met the inclusion and exclusion criteria established for the study. Data were collected from March 2013 to April 2014, by means of polysomnography, filming and observation for 24 uninterrupted hours. Descriptive statistics, the Friedman test, Pearson's correlation and linear regression, with significant values of p<0.05, were used. Results: The preterm infants studied were predominantly late preterm, female, with low birth weight, and a mean chronological age of 14 days. The newborns were handled an average of 176.4 (±37.9) times during a 24-hour period; 58% of the handling procedures were for monitoring. The proportion of total sleep time was 57.2% in 24 hours. There was no statistically significant correlation between frequency and duration of direct and ambient handling and the sleep of preterm infants in a 24-hour period. Single handling procedures had a strong positive correlation with wake time. Conclusion: Handling was related to monitoring, therapeutic/diagnostic and hygiene/comfort, with a prevalence of direct, single handling procedures. No statistically significant influence on the objective sleep variables was identified, except for single handling procedures where there was a correlation with wake time.

12.
Arq Neuropsiquiatr ; 75(4): 204-208, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28489138

RESUMO

Objective: To compare children with attention-deficit/hyperactivity disorder (ADHD), before and after the use of methylphenidate, and a control group, using tests of working memory, inhibition capacity and mental flexibility. Methods: Neuropsychological tests were administrated to 53 boys, 9-12 years old: the WISC-III digit span backward, and arithmetic; Stroop Color; and Trail Making Tests. The case group included 23 boys with ADHD, who were combined type, treatment-naive, and with normal intelligence without comorbidities. The control group (n = 30) were age and gender matched. After three months on methylphenidate, the ADHD children were retested. The control group was also retested after three months. Results: Before treatment, ADHD children had lower scores than the control group on the tests (p ≤ 0.001) and after methylphenidate had fewer test errors than before (p ≤ 0.001). Conclusion: Methylphenidate treatment improves the working memory, inhibitory control and mental flexibility of ADHD boys.


Assuntos
Transtorno do Deficit de Atenção com Hiperatividade/tratamento farmacológico , Estimulantes do Sistema Nervoso Central/administração & dosagem , Memória/efeitos dos fármacos , Metilfenidato/administração & dosagem , Estudos de Casos e Controles , Estimulantes do Sistema Nervoso Central/farmacologia , Criança , Humanos , Masculino , Metilfenidato/farmacologia , Testes Neuropsicológicos , Resultado do Tratamento
13.
Arq. neuropsiquiatr ; 75(4): 204-208, Apr. 2017. tab
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-838898

RESUMO

ABSTRACT Objective To compare children with attention-deficit/hyperactivity disorder (ADHD), before and after the use of methylphenidate, and a control group, using tests of working memory, inhibition capacity and mental flexibility. Methods Neuropsychological tests were administrated to 53 boys, 9–12 years old: the WISC-III digit span backward, and arithmetic; Stroop Color; and Trail Making Tests. The case group included 23 boys with ADHD, who were combined type, treatment-naive, and with normal intelligence without comorbidities. The control group (n = 30) were age and gender matched. After three months on methylphenidate, the ADHD children were retested. The control group was also retested after three months. Results Before treatment, ADHD children had lower scores than the control group on the tests (p ≤ 0.001) and after methylphenidate had fewer test errors than before (p ≤ 0.001) Conclusion Methylphenidate treatment improves the working memory, inhibitory control and mental flexibility of ADHD boys.


RESUMO Objetivo Comparar crianças com transtorno de déficit de atenção/hiperatividade (TDAH) com controles, utilizando testes de memória de trabalho, capacidade inibitória e flexibilidade mental, em meninos de 9 a 12 anos. Métodos Testes neuropsicológicos administrados: teste de ordem inversa dos dígitos, teste aritmético (WISC-III), Teste Stroop e Teste de Trilhas. Grupo experimental meninos (n=23), com TDAH combinado, virgens de tratamento, inteligência normal sem comorbidades. Grupo controle (n = 30) com as mesmas características do grupo experimental em termos de idade e sexo. Após três meses com metilfenidato, os grupos TDAH e controle foram novamente testadas. Resultados Antes do tratamento, as crianças com TDAH apresentaram menor pontuação do que o grupo controle nos testes analisados (p≤ 0.001) e o grupo com TDAH apresentou menos erros nos testes após metilfenidato (p ≤ 0.001). Conclusão O tratamento com metilfenidato melhora a memória de trabalho, controle inibitório e flexibilidade mental de meninos com TDAH.

14.
J Obstet Gynecol Neonatal Nurs ; 46(2): 238-247, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28056335

RESUMO

OBJECTIVE: To describe the total sleep time, stages of sleep, and wakefulness of preterm newborns and correlate them to levels of sound pressure, light, temperature, relative air humidity, and handling inside incubators. DESIGN: Observational, correlational study. SETTING: A neonatal intermediate care unit. PARTICIPANTS: Twelve preterm newborns, who were 32.2 ± 4.2 weeks gestational age and weighed 1,606 ± 317 g. METHODS: Sleep records were assessed by polysomnograph. Environmental variables were measured with a noise dosimeter, light meter, and thermohygrometer. To record time and frequency of handling, a video camera was used. All recordings were made for an uninterrupted 24-hour period. RESULTS: Mean total sleep time in 24 hours was 899 ± 71.8 minutes (daytime = 446 ± 45.3 and nighttime = 448 ± 60.2). Mean wakefulness was 552 ± 94.0 minutes. The predominant stage was quiet sleep. A significant correlation was identified only between the levels of light and wakefulness (r = 0.65 and p = .041). CONCLUSION: The environmental conditions and care provided to hospitalized preterm newborns did not influence sleep except for high light levels, which increased wakefulness. Nurses in clinical practice should implement strategies to promote and protect sleep by decreasing newborns' exposure to excessive light.


Assuntos
Exposição Ambiental , Recém-Nascido Prematuro/fisiologia , Unidades de Terapia Intensiva Neonatal , Iluminação , Ruído , Sono/fisiologia , Vigília/fisiologia , Exposição Ambiental/efeitos adversos , Exposição Ambiental/prevenção & controle , Feminino , Idade Gestacional , Humanos , Incubadoras para Lactentes/normas , Recém-Nascido , Unidades de Terapia Intensiva Neonatal/organização & administração , Unidades de Terapia Intensiva Neonatal/normas , Iluminação/efeitos adversos , Iluminação/métodos , Iluminação/normas , Masculino , Ruído/efeitos adversos , Ruído/prevenção & controle , Polissonografia/métodos
15.
Audiol., Commun. res ; 22: e1759, 2017. tab, graf
Artigo em Português | LILACS | ID: biblio-838929

RESUMO

RESUMO Introdução Pesquisas voltadas para as populações com baixas exposições a solventes, ou exposições dentro dos níveis de tolerância permitidos em âmbito ocupacional ainda são restritas. Objetivo Caracterizar o perfil auditivo de frentistas de postos de combustíveis. Métodos Estudo transversal, constituído por dois grupos, pareados por gênero e idade: Grupo Controle - 23 indivíduos sem exposição a ruído ou agentes químicos; Grupo Experimental - 21 frentistas de postos de combustíveis. Foi realizada avaliação audiológica, composta por audiometria tonal liminar, logoaudiometria e medidas de imitância acústica. A análise estatística utilizou cálculo de média, desvio padrão, valor mínimo e máximo, teste Qui-quadrado e coeficiente de correlação de Pearson. O nível de significância adotado foi de 5%. Resultados Foram verificadas alterações auditivas nos frentistas, caracterizadas por comprometimento no sistema auditivo periférico, sugerindo ação tóxica da exposição a combustíveis. Houve correlação entre idade e tempo de exposição a solvente. Na comparação entre os grupos, o reflexo acústico demonstrou maior número de alterações no grupo experimental, com diferença para os reflexos acústicos ipsilaterais da orelha direita e contralaterais da orelha esquerda. Conclusão Não houve diferença entre os grupos para os limiares auditivos, porém, a diferença verificada nos reflexos acústicos ipsilaterais e contralaterais no grupo experimental sugere comprometimento retrococlear. Diante das evidências observadas neste estudo, considera-se relevante incluir a pesquisa do reflexo acústico na avaliação auditiva dos frentistas, bem como a integração desta categoria profissional aos programas de prevenção de perda auditiva.


ABSTRACT Introduction Researches into populations with low solvent exposures, or exposures within tolerance levels allowed in the occupational field are still restricted. Purpose To characterize the hearing profile of gas station attendants. Methods Cross-sectional study, constituted of two groups, matched by gender and age: Control Group - 23 subjects without exposure to noise or chemicals; Experimental Group - 21 gas station attendants. An audiological evaluation was performed, composed by pure tone audiometry, speech audiometry and acoustic impedance tests. The statistical analysis used average calculation, standard deviation, minimum and maximum value; Chi-square Test and Pearson’s correlation coefficient. The significance level was 5%. Results Hearing loss was verified in gas station attendants characterized by impairment of the peripheral auditory system, suggesting toxic effects of exposure to fuels. There was a correlation between age and solvent exposure time. Comparing the groups, the acoustic reflex showed more alterations in the experimental group, with a difference for the ipsilateral acoustic reflexes of the right ear and contralateral ones of the left ear. Conclusion There was no difference between the groups for the hearing thresholds; however, the difference observed in the ipsilateral and contralateral acoustic reflexes in the experimental group suggests retrocochlear impairment. Due to the evidence observed in this study, it is considered relevant to include the acoustic reflex research in the auditory evaluation of the gas station attendants, as well as the integration of this professional category into hearing loss prevention programs.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Gasolina/efeitos adversos , Perda Auditiva/complicações , Hidrocarbonetos/efeitos adversos , Exposição Ocupacional/efeitos adversos , Audiometria , Hidrocarbonetos Aromáticos com Pontes , Exposição a Produtos Químicos , Posto de Combustível , Testes Auditivos , Nível de Percepção Sonora , Reflexo Acústico , Solventes/efeitos adversos , Teste do Limiar de Recepção da Fala
16.
Nursing (Säo Paulo) ; 17(222): 1266-1270, abr. 2016. tab
Artigo em Português | LILACS, BDENF - Enfermagem | ID: lil-786928

RESUMO

Objetivo: Este estudo objetivou verificar o impacto da espiritualidade no enfrentamento do processo de adoecimento e na qualidade de vida em pacientes com de diagnóstico de câncer. Método: O estudo foi realizado com em 30 pacientes com idade média de 46,6±14 anos, 52% eram do gênero feminino, 56% católicos e 72% casados, Resultados: Identificou-se para o conceito de fé pessoal 32,1 ±3; prática religiosa 29,5 ±7 e paz espiritual 32 ±6, A média dos escores para a qualidade de vida global foi 3,9± 1 e a satisfação com a saúde 3,6± 1, Quanto à associação do escore total da escala de espiritual idade com os domínios de qualidade de vida (físico, psicológico, social e meio ambiente), observou-se apenas a associação da espiritual idade com o domínio físico, Conclusão: Concluindo os elevados escores de paz espiritual em pacientes oncológicos, demonstrou impactar na qualidade de vida promovendo o enfrentamento da doença.


Objective: We examined the impact of spirituality in coping with the disease process and the quality of life in patients with a diagnosis of cancer Method: The study was conducted in 30 patients with mean age of 46,6 ± 14 years, 52% were female, 56% Catholic and 72% rnarried. Results: We identified the concept of personal faith 32,1 ± 3; religious practice and 29.5 ± 7 32 ± 6 spiritual peace. Mean scores for overall quality of life was 3,9 ± 1, and satisfaction with health 3,6 ± 1, In relation the association of the total score of spirituality with the areas of quality of life (physical, psychological, social and environment), we observed the association of the spirituality with the physical domam. Conclusion: In conclusion the high scores of spiritual peace in cancer patient, demonstrated impact on quality of life by promoting coping with the disease.


Objetivo: Valorar el impacto de la espiritualidad para lidiar con el proceso de la enfermedad y la calidad de vida en pacientes con un diagnóstico de cáncer, Método: El estudio se realizó en 30 pacientes con edad media de 46,6 ± 14 anos, el 52 % eran mujeres, 56% católica y se casó con un 72%, Resultados: Se identificó el concepto de Ia fe personal 32,1 ± 3; la práctica religiosa y de 29,5 ± 7 32 ± 6 Ia paz espiritual. Las puntuaciones medias de calidad de vida fue de 3,9 ± 1, Y Ia satisfacción con Ia salud de 3,6 ± 1, En cuanto a la asociación de la puntuación total de la espiritualidad con las áreas de calidad de vida (física, psicológica, social y medio ambiente), que sólo se observa la asociación de la espiritualidad con el dominio físico, Conclusión: Se concluye que las puntuaciones más altas de la paz espiritual demostrado impacto en la calidad de vida mediante la promoción de afrontamiento de la enfermedad.


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Espiritualidade , Neoplasias/diagnóstico , Pacientes/psicologia , Qualidade de Vida , Bioética , Saúde Holística
17.
Arq Neuropsiquiatr ; 74(2): 93-8, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26982984

RESUMO

OBJECTIVE: We evaluated extratemporal metabolic changes with phosphorus magnetic resonance spectroscopy (31P-MRS) in patients with unilateral mesial temporal sclerosis (MTS). METHOD: 31P-MRS of 33 patients with unilateral MTS was compared with 31 controls. The voxels were selected in the anterior, posterior insula-basal ganglia (AIBG, PIBG) and frontal lobes (FL). Relative values of phosphodiesters- PDE, phosphomonoesters-PME, inorganic phosphate - Pi, phosphocreatine- PCr, total adenosine triphosphate [ATPt = γ- + a- + b-ATP] and the ratios PCr/ATPt, PCr/γ-ATP, PCr/Pi and PME/PDE were obtained. RESULTS: We found energetic abnormalities in the MTS patients compared to the controls with Pi reduction bilaterally in the AIBG and ipsilaterally in the PIBG and the contralateral FL; there was also decreased PCr/γ-ATP in the ipsilateral AIBG and PIBG. Increased ATPT in the contralateral AIBG and increased γ-ATP in the ipsilateral PIBG were detected. CONCLUSION: Widespread energy dysfunction was detected in patients with unilateral MTS.


Assuntos
Espectroscopia de Ressonância Magnética/métodos , Fósforo/metabolismo , Lobo Temporal/patologia , Adulto , Estudos de Casos e Controles , Epilepsia do Lobo Temporal/metabolismo , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Esclerose/diagnóstico , Esclerose/metabolismo , Lobo Temporal/metabolismo , Adulto Jovem
18.
Arq. neuropsiquiatr ; 74(2): 93-98, Feb. 2016. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: lil-776444

RESUMO

ABSTRACT Objective We evaluated extratemporal metabolic changes with phosphorus magnetic resonance spectroscopy (31P-MRS) in patients with unilateral mesial temporal sclerosis (MTS). Method 31P-MRS of 33 patients with unilateral MTS was compared with 31 controls. The voxels were selected in the anterior, posterior insula-basal ganglia (AIBG, PIBG) and frontal lobes (FL). Relative values of phosphodiesters- PDE, phosphomonoesters-PME, inorganic phosphate - Pi, phosphocreatine- PCr, total adenosine triphosphate [ATPt = γ- + a- + b-ATP] and the ratios PCr/ATPt, PCr/γ-ATP, PCr/Pi and PME/PDE were obtained. Results We found energetic abnormalities in the MTS patients compared to the controls with Pi reduction bilaterally in the AIBG and ipsilaterally in the PIBG and the contralateral FL; there was also decreased PCr/γ-ATP in the ipsilateral AIBG and PIBG. Increased ATPT in the contralateral AIBG and increased γ-ATP in the ipsilateral PIBG were detected. Conclusion Widespread energy dysfunction was detected in patients with unilateral MTS.


RESUMO Objetivo Nós avaliamos as alterações metabóblicas através da espectroscopia de fósforo por ressonância magnética (31P-MRS) em pacientes com esclerose mesial temporal (EMT) unilateral. Método 31P-MRS de 33 pacientes com EMT unilateral foram comparadas aos de 31 controles. Foram selecionados os voxels nas regiões insulonuclear anterior e posterior (RINA e RINP) e frontal (RF). Os valores relativos de fosfodiésteres – PDE, fosfomonoésteres- PME, fosfato inorgânico- Pi, fosfocreatina –PCr, adenosina trifosfato total [ATPt = γ- + a- + b-ATP] e as razões PCr/ATPt, PCr/γ-ATP, PCr/Pi e PME/PDE foram obtidas. Resultados Nós encontramos anormalidades em pacientes com EMT em comparação aos controles. Redução de Pi nas RINA bilateralmente, RINP ipsilateral e RF contralateral, redução de PCr/γ-ATP nas RINA e RINP ipsilaterais foram detectadas. Aumentos de ATPT na RINA contralateral e aumento de γ-ATP na RINP ipsilateral também foram encontradas. Conclusão Disfunção energética difusa foi encontrada em pacientes com EMT unilateral.

19.
Rev Bras Enferm ; 68(6): 1109-15, 2015.
Artigo em Inglês, Português | MEDLINE | ID: mdl-26676434

RESUMO

OBJECTIVE: to describe the total sleep time and its stages, total wake time, heart rate values and oxygen saturation shown by premature infants, and the influence of the periods of the day on sleep and physiological parameters. METHOD: a descriptive study was conducted of 13 hospitalized premature infants. Data collection was performed using polysomnography and unstructured observation for 24 uninterrupted hours. RESULTS: the newborns remained asleep for 59.6% of the day, predominantly in quiet sleep, with a higher mean heart rate during wakefulness (p<0.001). No difference was found between the variables related to sleep, physiological parameters and periods of the day, but in the morning a predominance of quiet sleep was observed (p=0.002). CONCLUSION: the preterm newborn presented more total sleep time than wakefulness; quiet sleep was the predominant stage, and heart rate was higher during wakefulness.


Assuntos
Polissonografia , Sono , Feminino , Frequência Cardíaca , Humanos , Recém-Nascido , Recém-Nascido Prematuro , Masculino , Vigília
20.
Audiol., Commun. res ; 20(4): 313-320, out.-dez. 2015. tab, graf
Artigo em Inglês | LILACS | ID: lil-770543

RESUMO

RESUMO Objetivo: Estabelecer o perfil audiológico de motoristas agrícolas expostos, simultaneamente, a ruído e hidrocarbonetos. Métodos: Foram analisados os prontuários de motoristas com queixas auditivas de uma empresa do ramo agrícola do município de Lençóis Paulista (SP), dentro do Programa de Prevenção de Riscos Ambientais (PPRA). As informações analisadas foram: idade, tempo de exposição combinada a ruído e hidrocarbonetos e exames de audiometria tonal liminar de referência. Para a análise da influência da idade e do tempo de exposição sobre os limiares auditivos, ajustaram-se modelos de sobrevivência para dados grupados (riscos proporcionais e logísticos). Resultados: Verificou-se que os efeitos da idade e do tempo de exposição combinada a ruído e hidrocarbonetos foram significativos na perda de audição, nos modelos de riscos proporcionais e logísticos. Conclusão: É fundamental o desenvolvimento de ações voltadas para a prevenção de perdas auditivas em motoristas agrícolas expostos aos agentes ruído e hidrocarbonetos.


ABSTRACT Purpose: To establish the audiological profile of agricultural drivers simultaneously exposed to noise and hydrocarbons. Methods: The study comprised analysis of the medical records of agricultural drivers with hearing complaints, from an agricultural company of Lençóis Paulista (SP), Brazil, within the Environmental Risk Prevention Program. The information analyzed included age, period of simultaneous exposure to noise and hydrocarbons and testing of reference pure tone audiometry. Survival models for grouped data (proportional risk and logistic) were adjusted to analyze the influence of age and period of exposure of hearing thresholds. Results: It was observed that the effects of age and period of simultaneous exposure to noise and hydrocarbons were significant for hearing loss in proportional risk and logistic models. Conclusion: It is fundamental to develop actions for the prevention of hearing loss in agricultural drivers exposed to the agents noise and hydrocarbons.


Assuntos
Humanos , Adulto , Pessoa de Meia-Idade , Agroquímicos/efeitos adversos , Perda Auditiva Provocada por Ruído , Hidrocarbonetos/efeitos adversos , Exposição Ocupacional , Audiometria , Estudos de Coortes , Riscos Ambientais , Perda Auditiva/prevenção & controle , Programa de Prevenção de Riscos no Ambiente de Trabalho
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