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1.
Homeopathy ; 2021 Feb 22.
Artigo em Inglês | MEDLINE | ID: mdl-33618380

RESUMO

Thromboinflammation is a still not well-understood phenomenon, which has recently come to the foreground as a function of its relevance in the pathophysiology of coronavirus disease 2019 (COVID-19). The patient described in the present case report exhibited acute fever, giant urticaria, elevated acute phase reactants, and very high d-dimer levels, thus characterizing thromboinflammation. She was diagnosed as a COVID-19 suspect case, which was not confirmed; urticarial vasculitis was ruled out. Homeopathic treatment was started with the earliest clinical manifestations, resulting in rapid and drastic reduction of inflammation and hypercoagulability within the first 12 hours, and full recovery on 10-day follow-up assessment. This case demonstrates the effectiveness of homeopathy in a severe acute disorder, and points to the need to include laboratory testing in homeopathic clinical assessment to achieve an accurate picture of disease, and to avoid the risk of passing over life-threatening disorders.

2.
Homeopathy ; 110(1): 36-41, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33482668

RESUMO

BACKGROUND: The reliability of homeopathic prescriptions may increase through resource to objective signs and guiding symptoms with significant positive likelihood ratio (LR). We estimated LR for six objective signs attributed to the homeopathic medicine Natrum muriaticum (Nat-m). METHODS: In this multi-centre observational assessment, we investigated the prevalence of six signs in the general patient population and among good responders to Nat-m in daily homeopathic practice. Next, we calculated LR for these six signs. RESULTS: Data from 36 good responders to Nat-m and 836 general population patients were compared. We found statistically significant positive LR (95% confidence interval) for signs such as lip cracks (1.94; 1.15 to 3.24), recurrent herpes (2.29; 1.20 to 4.37), hairline eruptions (2.07; 1.03 to 4.18), and dry hands (2.13; 1.23 to 3.69). CONCLUSIONS: Objective signs with significant positive LR might increase the reliability of homeopathic prescriptions. Further studies are warranted to confirm the validity of this approach.

3.
Homeopathy ; 110(1): 52-61, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33348418

RESUMO

BACKGROUND: The homeopathic medicines Silicea terra (Sil) and Zincum metallicum (Zinc) modulate macrophage activity and were assessed in an experimental study in-vitro for their effects on macrophage-BCG (Bacillus Calmette-Guérin) interaction. METHODS: RAW 264.7 macrophages were infected with BCG, treated with different potencies of Sil and Zinc (6cH, 30cH and 200cH) or vehicle, and assessed 24 and 48 h later for bacilli internalization, hydrogen peroxide (H2O2) and cytokine production, and lysosomal activity. RESULTS: Treatment with vehicle was associated with non-specific inhibition of H2O2 production to the levels exhibited by uninfected macrophages. Sil 200cH induced significant reduction of H2O2 production (p < 0.001) compared with the vehicle and all other treatments, as well as higher lysosomal activity (p ≤ 0.001) and increased IL-10 production (p ≤ 0.05). Such effects were considered specific for this remedy and potency. The number of internalized bacilli was inversely proportional to Zinc potencies, with statistically significant interaction between dilution and treatment (p = 0.003). Such linear-like behavior was not observed for Sil dilutions: peak internalization occurred with the 30cH dilution, accompanied by cellular degeneration, and IL-6 and IL-10 increased (p ≤ 0.05) only in the cells treated with Sil 6cH. CONCLUSION: Sil and Zinc presented different patterns of potency-dependent effect on macrophage activity. Bacterial digestion and a balanced IL-6/IL-10 production were related to Sil 6cH, though reduced oxidative stress with increased lysosomal activity was related to Sil 200cH. Degenerative effects were exclusively related to Sil 30cH, and potency-dependent phagocytosis was related only to Zinc.

4.
Homeopathy ; 2020 Dec 21.
Artigo em Inglês | MEDLINE | ID: mdl-33348419

RESUMO

BACKGROUND: Complementary and alternative medicine, including homeopathy, is widely used to improve well-being among cancer patients and reduce adverse effects of conventional treatment. In contrast, there are few studies on the use of homeopathic medicines to treat the disease itself. Yet, evidence of possible effectiveness of homeopathic high dilutions in experimental cancer models has been published during the past 20 years. AIM: The aim of the study was to perform a systematic review of fundamental research studies on homeopathic high dilutions in cancer. METHODS: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline, we conducted a literature search in the database PubMed for original publications, from 2000 to 2018 and in English, on in vitro and in vivo experimental cancer models testing homeopathic high dilutions. RESULTS: Twenty-three articles met the inclusion criteria-14 in vitro, eight in vivo, and one in vitro plus in vivo experimental models. Most studies were from India. Research prominently focused on cytotoxic effects involving apoptotic mechanisms. Intrinsic aspects of homeopathy should be considered in experimental designs to emphasize the specificity of such effects. CONCLUSION: Fundamental research of homeopathy in cancer is still at an early stage and has mainly been performed by a few groups of investigators. The results point to an interference of well-selected homeopathic medicines with cell cycle and apoptotic mechanisms in cancer cells. However, these findings still need independent reproduction.

5.
Homeopathy ; 109(3): 169-175, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32698230

RESUMO

Successful homeopathic prescriptions are based on careful individualization of symptoms, either for an individual patient or collectively in the case of epidemic outbreaks. The ongoing COVID-19 pandemic was initially represented as a severe acute respiratory illness, with eventual dramatic complications. However, over time it revealed to be a complex systemic disease with manifestations derived from viral-induced inflammation and hypercoagulability, thus liable to affect any body organ or system. As a result, clinical presentation is variable, in addition to variations associated with several individual and collective risk factors. Given the extreme variability of pathology and clinical manifestations, a single, or a few, universal homeopathic preventive Do not split medicine(s) do not seem feasible. Yet homeopathy may have a relevant role to play, inasmuch as the vast majority of patients only exhibit the mild form of disease and are indicated to self-care at home, without standard monitoring, follow-up, or treatment. For future pandemics, homeopathy agencies should prepare by establishing rapid-response teams and efficacious lines of communication.


Assuntos
Betacoronavirus , Infecções por Coronavirus/tratamento farmacológico , Homeopatia/métodos , Pneumonia Viral/tratamento farmacológico , Humanos , Pandemias
6.
Hist Cienc Saude Manguinhos ; 26(4): 1281-1297, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31800842

RESUMO

The comparative approach has been advocated to overcome some flaws inherent to case studies. Here, the spread of homeopathy in the early nineteenth century is addressed through a comparison of the cases of Sweden and Brazil, where homeopathy met diametrically opposed fates. The parameters used for the comparison are the standard for studies on the early spread of homeopathy, such as the concept of the "introducer," and reception by the medical and academic community, the government, and society at large. The results suggest that analysis of contexts, determinants, and the interactions of practitioners and institutions representing different health care approaches, whether dominant or alternative, seems to provide a more accurate picture of different moments in the global history of medicine.


Assuntos
Homeopatia/história , Atitude do Pessoal de Saúde/etnologia , Atitude Frente a Saúde/etnologia , Brasil , Comparação Transcultural , História do Século XIX , Médicos/história , Suécia
7.
Hist. ciênc. saúde-Manguinhos ; 26(4): 1281-1297, out.-dez. 2019.
Artigo em Inglês | LILACS | ID: biblio-1056269

RESUMO

Abstract The comparative approach has been advocated to overcome some flaws inherent to case studies. Here, the spread of homeopathy in the early nineteenth century is addressed through a comparison of the cases of Sweden and Brazil, where homeopathy met diametrically opposed fates. The parameters used for the comparison are the standard for studies on the early spread of homeopathy, such as the concept of the "introducer," and reception by the medical and academic community, the government, and society at large. The results suggest that analysis of contexts, determinants, and the interactions of practitioners and institutions representing different health care approaches, whether dominant or alternative, seems to provide a more accurate picture of different moments in the global history of medicine.


Resumo A abordagem comparativa foi adotada com o intuito de suplantar algumas falhas inerentes aos estudos de caso. Nela, a difusão da homeopatia no início do século XIX é tratada por meio de uma comparação entre casos da Suécia e do Brasil, onde a homeopatia encontrou destinos diametralmente opostos. Os parâmetros usados para a comparação são padrão para estudos sobre o início da expansão da homeopatia, como o conceito de "introdutor", e a aceitação por parte de governo, comunidades médica e acadêmica, e sociedade como um todo. Os resultados sugerem que a análise de contextos, de determinantes, e das interações de médicos e instituições representando diferentes perspectivas de tratamento médico, fossem elas dominantes ou alternativas, parecem oferecer uma análise mais precisa de diferentes momentos da história global da medicina.


Assuntos
História do Século XIX , Homeopatia/história , Médicos/história , Suécia , Brasil , Atitude do Pessoal de Saúde/etnologia , Atitude Frente a Saúde/etnologia , Comparação Transcultural
8.
Homeopathy ; 108(1): 12-23, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30290377

RESUMO

INTRODUCTION: According to the "silica hypothesis" formulated to explain homeopathy, the information of starting materials would be transferred to cells by silica nanoparticles detached from the glassware walls by serial dilution and agitation through epitaxy. We compared the biological activity, electrical current and silicon microparticle content (by means of scanning electron microscopy/energy-dispersive X-ray spectroscopy) of high dilutions (HDs) of arsenic prepared in plastic and glass vials to investigate the role of silica in their biological effects in vitro. MATERIALS AND METHODS: Co-cultures of macrophages and yeast (Saccharomyces cerevisiae) were treated with different HDs of arsenic prepared in plastic and glass vials. Macrophage morphology, phagocytosis index, nitric oxide (NO), and cytokine production were evaluated. RESULTS: Measurable amounts of silicon microparticles were detected only in the HDs prepared in glass vials, but ultra-centrifugation eliminated them. Specific and non-specific results were observed. Non-specific pro-inflammatory effects were seen in all dilutions prepared in plastic vials, including elevation of pro-inflammatory cytokines, NO and macrophage phagocytic index. Only the 200th centesimal dilution of arsenic produced specific decrease in interleukin-6 production in macrophages, and it was independent of the vial type or the presence of microparticles of silica in the medicine samples. The nature of the vials had an impact on the electric flow in the respective fluids. CONCLUSION: The non-specific, pro-inflammatory effects might be attributed to organic residuals detached from the vials' plastic walls during manipulation. Instead, specific silica-independent effects of the homeopathic medicine can be attributed to the decrease of interleukin-6 after treatment with the 200th centesimal dilution of arsenic.


Assuntos
Arsenicais/isolamento & purificação , Condutividade Elétrica , Silício/isolamento & purificação , Citocinas/isolamento & purificação , Homeopatia/métodos , Humanos , Microscopia Eletrônica de Varredura/métodos
9.
Hist. ciênc. saúde-Manguinhos ; 26(4): 1281-1297, out.-dez. 2019.
Artigo em Inglês | HISA - História da Saúde | ID: his-44249

RESUMO

The comparative approach has been advocated to overcome some flaws inherent to case studies. Here, the spread of homeopathy in the early nineteenth century is addressed through a comparison of the cases of Sweden and Brazil, where homeopathy met diametrically opposed fates. The parameters used for the comparison are the standard for studies on the early spread of homeopathy, such as the concept of the “introducer,” and reception by the medical and academic community, the government, and society at large. The results suggest that analysis of contexts, determinants, and the interactions of practitioners and institutions representing different health care approaches, whether dominant or alternative, seems to provide a more accurate picture of different moments in the global history of medicine.


Assuntos
História da Homeopatia , História da Medicina , Estudo Comparativo , História do Século XIX
10.
Int. j. high dilution res ; 17(3/4): 20-41, 2018.
Artigo em Inglês | LILACS, HomeoIndex - Homeopatia | ID: biblio-1050007

RESUMO

Introduction: The aim of the present study was to describe different biological aspects of Ehrlich tumor in mice, such as body weight evolution, tumor growth rate, histological organization and systemic immune response after treatment with high-diluted thymulin (10-9 M, named 5CH). Methods: Tumor assessment was focused on macro- and microscopic aspects; parameters included occurrence of necrosis, embolism and tumor development, in addition to quantitative analysis of apoptosis (caspase-3), cell proliferation (Ki-67) and angiogenesis (vascular endothelial growth factor - VEGF) by means of specific immunohistochemistry markers. Spleen cell populations were evaluated by flow cytometry analysis. Results: Mice treated with thymulin 5CH exhibited changes in the tumor microenvironment, such as reduced micro-embolism incidence and cytokeratin expression, with increased caspase-3 expression in the tumor cells. These findings indicate some apoptotic activity by the tumor cells induced by the treatment, even though no reduction of the macroscopic tumor mass occurred. No changes in the systemic immune response were detected, as the balance among spleen cell populations remained unchanged. Conclusions: The results indicate that treatment of mice bearing Ehrlich tumor with thymulin 5CH induces some specific changes in the tumor environment. However, it did not influence systemic immunity parameters. Adjuvant use of thymulin 5CH in oncological clinical practice is still a matter of discussion. (AU)


Assuntos
Animais , Camundongos , Carcinoma de Ehrlich , Altas Potências , Thymolum , Neoplasias
11.
Homeopathy ; 106(4): 250-259, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-29157474

RESUMO

Medicine underwent a major crisis in the 18th century and several approaches, including homeopathy, were formulated to fill the void left by the fall of traditional Galenic medicine. While most of the literature deals with the reasons doctors had to shift to homeopathy, the patients' views became the focus of increasing scholarly attention along the past 20 years. In this article I present and discuss the current knowledge about the socio-demographic characteristics and medical complaints of patients who sought homeopathic care in the early 19th century in both private and institutional settings. The results show that not only patients from the higher and more educated classes sought homeopathic care, but a considerable number of individuals from the middle and lower strata did so too, even though they also had access to conventional hospitals. As to the clinical complaints, the reasons to seek homeopathic care were the typical ones for any general practice or hospital in the period considered.


Assuntos
Medicina Geral/métodos , Homeopatia/história , Medicina Geral/história , História do Século XVIII , Homeopatia/métodos , Humanos
12.
Exp Ther Med ; 13(6): 2723-2740, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28596809

RESUMO

Mistletoe (Viscum album L.) has been used as complementary anticancer treatment for ~100 years. Although the clinical efficacy of mistletoe in cancer and associated survival benefits remain contested, several studies point to its effectiveness and others have reported antitumor and immunomodulatory properties. In the present review, a search was conducted for original articles reporting the outcomes of treatments for experimental animal tumors with mistletoe. The inclusion criteria were: Publication in English, from 1996 onwards and in peer-reviewed journals included in the database PubMed. The parameters analyzed were: Provenance and time of publication, rationale, methods (animal species used, mistletoe preparation, treatment protocol, tumor lineage, blinding, randomization, controls and concomitant treatments), outcomes and investigated mechanisms of action. A total of 37 studies met the inclusion criteria. The quality of the studies was adequate in the terms of sample size and use of controls, and the only animal species employed were mice and rats. However, few studies reported having performed random allocation and none reported blinding. There was wide variation in the type and preparation of mistletoe used, route of administration, regimen, tumor type and the mechanism of action assessed. A temporal trend was identified; earlier studies sought to establish the antitumor effect of mistletoe and its possible mechanisms, cytotoxicity and immunomodulation in particular, whereas the later ones tended to focus more on biologically active principles, genomics and oxidative stress. A total of 32/37 studies reported an antitumor effect, 3 of which had mixed results. A total of 2 studies did not detect any antitumor effect and a further 2 found stimulation of tumor growth in the treated groups. One study did not assess antitumor effects, investigating immunomodulation action instead. The quality of the studies was satisfactory and the majority reported positive outcomes. Nevertheless, there is a great deal of methodological heterogeneity among the studies, which precludes conclusive comparisons. Based on these results, the present authors strongly suggest developing guidelines for reporting in vivo mistletoe cancer treatment experiments.

13.
Homeopathy ; 106(2): 114-130, 2017 May.
Artigo em Inglês | MEDLINE | ID: mdl-28552174

RESUMO

In the present study, we investigated the experimental basis for the indications of homeopathic drug Zincum metallicum. The current body of knowledge about Zinc met has a core composed of pathogenetic and clinical data collected in the 19th century surrounded by layers of clinical observations reported over time. In the description, we prioritized poorly known sources, especially the ones that were never translated from the original German. We also performed quantitative and statistical analysis of repertory data. Through a literature survey and a call to practicing homeopathic doctors from many countries, we were able to put together a relevant case-series that represents homeopathic indications of Zinc.


Assuntos
Homeopatia/história , Alemanha , História do Século XIX , História do Século XX , Humanos , Estados Unidos , Zinco/uso terapêutico
14.
Homeopathy ; 106(1): 27-31, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-28325220

RESUMO

BACKGROUND: Resistance to antibiotics is a major public health concern worldwide. New treatment options are needed and homeopathy is one such option. We sought to assess the effect of the homeopathic medicine Belladonna (Bell) and a nosode (biotherapy) prepared from a multi-drug resistant bacterial species, methicillin-resistant Staphylococcus aureus (MRSA), on the same bacterium. METHODS: Bell and MRSA nosode were prepared in 6cH and 30cH potencies in 30% alcohol and sterile water, according to the Brazilian Homeopathic Pharmacopeia and tested on MRSA National Collection of Type Cultures (NCTC) 10442. We assessed in vitro bacterial growth, deoxyribonuclease (DNAase) and hemolysin activity, and in vitro bacterial growth in combination with oxacillin (minimum inhibitory concentration - MIC). All values were compared to control: 30% alcohol and water. RESULTS: In vitro growth of MRSA was statistically significantly inhibited in the presence of Bell and nosode 6cH and 30cH compared to controls (p < 0.0001); and with combination of Bell or nosode 6cH and 30cH and oxacillin (p < 0.001). Bell 30cH and nosode 6cH and 30cH significantly decreased bacterial DNAse production (p < 0.001) and reduced red blood cell lysis. CONCLUSIONS: Cultures of MRSA treated with Belladonna or MRSA nosode exhibited reduced growth in vitro, reduced enzymatic activity and became more vulnerable to the action of the antibiotic oxacillin. Further studies are needed on the biomolecular basis of these effects.


Assuntos
Anti-Infecciosos/farmacologia , Homeopatia , Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos , Oxacilina/farmacologia , Preparações de Plantas/farmacologia , Atropa belladonna , Relação Dose-Resposta a Droga , Quimioterapia Combinada , Humanos , Materia Medica , Resistência a Meticilina , Staphylococcus aureus Resistente à Meticilina/fisiologia , Testes de Sensibilidade Microbiana , Oxacilina/uso terapêutico
15.
Rev. homeopatia (São Paulo) ; 80(1/2): 98-112, 2017. tab
Artigo em Português | HomeoIndex - Homeopatia | ID: hom-11972

RESUMO

Introdução: Existem questionamentos quanto aos efeitos das ultradiluições (UDs) homeopáticas por ultrapassarem o número de Avogadro. Objetivo: Realizar uma revisão da literatura sobre os efeitos das UDs em modelos in vitro. Métodos: Foi realizada uma busca sistemática na base de dados PubMed de estudos sobre UDs simples em modelos in vitro a partir de 2007. Resultados: 28 publicações cumpriram os critérios de inclusão/exclusão; 26 estudos demonstraram efeitos evidentes de UDs simples em modelos in vitro, a maioria originada em países onde a homeopatia tem alto grau de institucionalização. Conclusões: Estudos in vitro demonstram inquestionavelmente a atividade biológica de UDs acima do número de Avogadro, dando conta do efeito das mesmas na prática clínica. A maioria das pesquisas se origina em países onde a homeopatia é uma racionalidade médica oficialmente aceita, o que facilita o acesso a recursos de pesquisa. (AU)


Background: the effects of homeopathic high dilutions (HDs) are debated because they exceed Avogadro’s number, Aim: to perform a literature review on the effects of HDs on in vitro models. Methods: a systematic search was performed in database PubMed for studies assessing simple HDs on in vitro models published from 2007 onwards. Results: 28 publications met the inclusion/exclusion criteria; 26 studies demonstrated patent effects of simple HDs on in vitro models; most such studies were conducted in countries where homeopathy attained a high level of institutionalization. Conclusions: in vitro models patently evidence biological activity of HDs above Avogadro’s number and account for effects found in clinical practice. Most studies were conducted in countries where homeopathy is officially recognized, which facilitates the access to research. (AU)


Assuntos
Homeopatia , Altas Potências , Técnicas In Vitro
16.
Rev. homeopatia (São Paulo) ; 80(1/2): 133-147, 2017. tab
Artigo em Português | HomeoIndex - Homeopatia | ID: hom-11974

RESUMO

Introdução: Revisões sistemáticas e ensaios clínicos randomizados controlados (ERCs) são considerados os métodos com maior nível de evidência. Objetivo: Realizar uma revisão descritiva das revisões sistemáticas e ERCs sobre a efetividade e eficácia da homeopatia. Métodos: Utilização do relatório produzido pela Liga Médica Homeopática Internacional (LMHI) em 2014, com atualização dos estudos através de uma busca na base de dados PubMed. Resultados: Foram localizadas 7 revisões sistemáticas com metanálise, 6 delas indicando que os efeitos da homeopatia não são compatíveis com efeito placebo; apenas 1 revisão concluiu o resultado oposto, sendo extremamente criticada por apresentar sérias falhas metodológicas. Além disso, 19 ERCs foram publicados no período recente, 84,20% dos quais com pelo menos 1 desfecho positivo. Conclusões: Com base nas evidências disponíveis de maior nível não se pode afirmar que os efeitos da homeopatia são exclusivamente efeito placebo. Ao contrário, efeitos específicos foram identificados em diversos estudos. (AU)


Background: Systematic reviews and randomized clinical trials (RCTs) are considered to have the highest level of evidence. Aim: To perform a descriptive review of systematic reviews and RCTs on the effectiveness and efficacy of homeopathy. Methods: Data from the report published by Liga Medicorum Homeopathica Internationalis (LMHI) in 2014 updated by means on a search conducted in database PubMed. Results: 7 systematic reviews with meta-analysis were located, 6 of them conclude that the effects of homeopathy are not compatible with placebo effect; only 1 systematic review arrived to the opposite conclusion, but was severely criticized due to methodological flaws. A total of 19 RCTSs were published in the analyzed period; 844.20% had at least one positive outcome. Conclusions: Based on the available evidences of the highest level it is not possible to assert that the effects of homeopathic are exclusively placebo effect. On the opposite, specific effects were detected in several studies. (AU)


Assuntos
Homeopatia , Efeito Placebo , Efetividade , Eficácia , Resultado do Tratamento , Avaliação de Eficácia-Efetividade de Intervenções
17.
Rev. homeopatia (São Paulo) ; 80(3/4): 90-103, 2017. tab
Artigo em Inglês | HomeoIndex - Homeopatia | ID: hom-12035

RESUMO

Background: the effects of homeopathic high dilutions (HDs) are controversial because they exceed Avogadro’s number. Aim: to perform a literature review on the effects of HDs on in vitro models. Methods: a systematic search was performed in database PubMed for studies assessing simple HDs on in vitro models published from 2007 onward. Results: 28 publications met the inclusion/exclusion criteria; 26 studies demonstrated patent effects of simple HDs on in vitro models; most such studies were conducted in countries where homeopathy attained a high level of institutionalization.Conclusions: in vitro models patently evidence biological activity of HDs aboveAvogadro’s number and account for effects found in clinical practice. Most studies were conducted in countries where homeopathy is officially recognized, which facilitates access to resources for the development of research.(AU)


Assuntos
Homeopatia , Altas Potências , Técnicas In Vitro
18.
Rev. homeopatia (São Paulo) ; 80(1/2,supl): 57-65, 2017. tab
Artigo em Português | HomeoIndex - Homeopatia | ID: hom-12047

RESUMO

Introdução: Existem questionamentos quanto aos efeitos das ultradiluições (UDs) homeopáticas por ultrapassarem o número de Avogadro. Objetivo: Realizar uma revisão da literatura sobre os efeitos das UDs em modelos in vitro. Métodos: Foi realizada uma busca sistemática na base de dados PubMed de estudos sobre UDs simples em modelos in vitro a partir de 2007. Resultados: 28 publicações cumpriram os critérios de inclusão/exclusão; 26 estudos demonstraram efeitos evidentes de UDs simples em modelos in vitro, a maioria originada em países onde a homeopatia tem alto grau de institucionalização. Conclusões: Estudos in vitro demonstram inquestionavelmente a atividade biológica de UDs acima do número de Avogadro, dando conta do efeito das mesmas na prática clínica. A maioria das pesquisas se origina em países onde a homeopatia é uma racionalidade médica oficialmente aceita, o que facilita o acesso a recursos de pesquisa. (AU)


Assuntos
Homeopatia , Altas Potências , Técnicas In Vitro
19.
Rev. homeopatia (Säo Paulo) ; 80(3/4): 90-103, 2017. tab
Artigo em Inglês | LILACS | ID: biblio-973271

RESUMO

BACKGROUND: the effects of homeopathic high dilutions (HDs) are controversial because they exceed Avogadro’s number. AIM: to perform a literature review on the effects of HDs on in vitro models. METHODS: a systematic search was performed in database PubMed for studies assessing simple HDs on in vitro models published from 2007 onward. RESULTS: 28 publications met the inclusion/exclusion criteria; 26 studies demonstrated patent effects of simple HDs on in vitro models; most such studies were conducted in countries where homeopathy attained a high level of institutionalization. CONCLUSIONS: in vitro models patently evidence biological activity of HDs aboveAvogadro’s number and account for effects found in clinical practice. Most studies were conducted in countries where homeopathy is officially recognized, which facilitates access to resources for the development of research.


Assuntos
Homeopatia , Altas Potências , Técnicas In Vitro
20.
Hist. ciênc. saúde-Manguinhos ; 23(3): 779-798, Jul. - Set. 2016. ilus, tab
Artigo em Português | HomeoIndex - Homeopatia | ID: hom-11716

RESUMO

A homeopatia começou a propagar-se logo após sua formulação por Samuel Hahnemann, nos primeiros anos do século XIX, chegando ao Cone Sul na década de 1830. Esse processo é tradicionalmente vinculado à figura de um “introdutor”, por vezes alcançando estatuto mítico. No entanto, pouco se sabe acerca da chegada da homeopatia à Argentina nesse período. Com base em trabalho de arquivo, identificamos uma clara circulação de homeopatas médicos e leigos no eixo Rio de Janeiro-Buenos Aires. Dada a conhecida atividade proselitista desenvolvida nos círculos ligados aos homeopatas leigos B. Mure e J.V. Martins no Rio de Janeiro, a documentação disponível aponta para a possível extensão desse movimento também na Argentina, o que não tinha sido evidenciado até o presente. (AU)


Assuntos
História do Século XIX , Homeopatia/história , Documentação
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