Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 19 de 19
Filtrar
Filtros adicionais











Intervalo de ano
1.
Arq Neuropsiquiatr ; 77(3): 194-207, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30970133

RESUMO

BACKGROUND: Scotopic sensitivity syndrome, later called Meares-Irlen syndrome or simply Irlen syndrome (IS) has been described as symptoms of poor reading ability due to poor color matching and distorted graphic images. Individuals with this syndrome are considered slow, ineffective readers with low comprehension and visual fatigue. It is still uncertain whether the disease pathophysiology is an independent entity or part of the dyslexia spectrum. Nevertheless, treatments with lenses and colored filters have been proposed to alleviate the effect of the luminous contrast and improve patients' reading performance. However, no evidence of treatment effectiveness has been achieved. OBJECTIVE: The aim of the present study was to obtain evidence about IS etiology, diagnosis and intervention efficacy. METHODS: A systematic review was performed covering the available studies on IS, assessing the available data according to their level of evidence, focusing on diagnostic tools, proposed interventions and related outcomes. RESULTS: The data showed high heterogeneity among studies, and lack of evidence on the existence of IS and treatment effectiveness. CONCLUSION: The syndrome as described, as well as its treatments, require further strong evidence.

2.
Arq. neuropsiquiatr ; 77(3): 194-207, Mar. 2019. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-1001343

RESUMO

ABSTRACT Background: Scotopic sensitivity syndrome, later called Meares-Irlen syndrome or simply Irlen syndrome (IS) has been described as symptoms of poor reading ability due to poor color matching and distorted graphic images. Individuals with this syndrome are considered slow, ineffective readers with low comprehension and visual fatigue. It is still uncertain whether the disease pathophysiology is an independent entity or part of the dyslexia spectrum. Nevertheless, treatments with lenses and colored filters have been proposed to alleviate the effect of the luminous contrast and improve patients' reading performance. However, no evidence of treatment effectiveness has been achieved. Objective: The aim of the present study was to obtain evidence about IS etiology, diagnosis and intervention efficacy. Methods: A systematic review was performed covering the available studies on IS, assessing the available data according to their level of evidence, focusing on diagnostic tools, proposed interventions and related outcomes. Results: The data showed high heterogeneity among studies, and lack of evidence on the existence of IS and treatment effectiveness. Conclusion: The syndrome as described, as well as its treatments, require further strong evidence.


RESUMO Background: A síndrome da sensibilidade escotópica, posteriormente denominada síndrome de Meares-Irlen ou simplesmente síndrome de Irlen (SI), foi descrita como indivíduos com sintomas de baixa capacidade de leitura devido à combinação de cores e distorções nas imagens. Indivíduos com essa síndrome podem apresentar leitura lenta e ineficaz, com baixo nível de compreensão e fadiga visual. A fisiopatologia da doença ainda é incerta como uma entidade independente ou como parte do espectro da dislexia. No entanto, tratamentos com lentes e filtros coloridos foram propostos com o objetivo de aliviar o efeito do contraste luminoso e melhorar o desempenho de leitura dos pacientes. Outrossim, nenhuma evidência de eficácia do tratamento foi alcançada. Objetivos: Obter evidências sobre a etiologia, eficácia diagnóstica e intervenção da SI. Métodos: Foi realizada uma revisão sistemática, cobrindo os estudos disponíveis sobre a SI, avaliando os dados disponíveis de acordo com seu nível de evidência, com foco em ferramentas de diagnóstico, intervenções propostas e desfechos relacionados. Resultados: Os dados mostram alta heterogeneidade, falta de evidência sobre a existência da SI e eficácia do tratamento. Conclusões: A síndrome descrita e seus tratamentos exigem evidências mais robustas.

3.
Rev. bras. crescimento desenvolv. hum ; 26(2): 147-153, 2016. graf, tab
Artigo em Inglês | LILACS | ID: lil-797805

RESUMO

BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is categorized by a lowered attention span, recklessness, and hyperactivity. Autonomic nervous system inequality has previously been studied using the same data by chaotic global techniques. We aim to compare the autonomic function of children with ADHD and controls by analyzing heart rate variability (HRV) METHODS: 28 children with ADHD (22 boys, mean age 10.0 years ± 1.9 years) and 28 controls (15 boys, mean age 9.9 years ± 1.8 years) rested in supine position with spontaneous breathing for 20 minutes. Heart rate was recorded beat by beat. HRV analysis was performed by Higuchi Fractal Dimension technique. RESULTS: ADHD promoted an increase in the Higuchi Fractal Dimension. The optimum value of Kmax was 10. CONCLUSION: ADHD significantly altered cardiac autonomic modulation as measured by the Higuchi fractal dimension of HRV. It can therefore be stated that ADHD has increased the complexity of the HRV signal through cardiac autonomic modulation.


INTRODUÇÃO: O transtorno de deficit de atenção e hiperatividade (TDAH) é caracterizado por um período reduzido de atenção, impulsividade e hiperatividade. O desequilíbrio na função do sistema nervoso autônomo (SNA) tem sido previamente estudado utilizando-se técnicas globais da teoria do caos. OBJETIVO: comparar a função autonômica de crianças com TDAH e controles por meio da análise da variabilidade da frequência cardíaca (VFC) MÉTODO: 28 crianças com TDAH (22 meninos, com média de idade de 10,0 anos ± 1,9 anos) e 28 controles (15 meninos, com média de idade de 9,9 anos ± 1,8 anos) permaneceram em decúbito dorsal, com respiração espontânea por 20 minutos. A frequência cardíaca foi registrada batimento a batimento e a análise da VFC foi realizada pela técnica de Dimensão Fractal Higuchi. RESULTADOS: TDAH promoveu um aumento na Dimensão Fractal Higuchi. O valor ideal de Kmax foi 10. CONCLUSÃO: O TDAH alterou significantemente a modulação autonômica cardíaca, como demonstrado pela Dimensão Fractal Higuchi da VFC. Assim, pode-se afirmar que crianças com TDAH apresentaram aumento das respostas caóticas neste tipo de análise da modulação autonômica cardíaca.


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Transtorno do Deficit de Atenção com Hiperatividade , Sistema Nervoso Autônomo , Cognição , Frequência Cardíaca , Arritmias Cardíacas , Psiquiatria Infantil , Terapêutica
4.
Artigo em Inglês | LILACS | ID: lil-765997

RESUMO

A meningite é a principal síndrome infecciosa que afeta o sistema nervoso central, e grande parte dos casos são ocasionados por infecções virais, principalmente por Enterovirus. O diagnóstico clínico para a verificação da etiologia da meningite ainda apresenta grandes desafios. O teste de Reação em Cadeia da Polimerase, leucócitos, hemácias, glicose, proteína e lactato no líquido cefalorraquidiano fornecem os primeiros indícios para o diagnóstico. No entanto, os valores de referência de alguns parâmetros podem sofrer alteraçõesOBJETIVO: Verificar parâmetros laboratoriais do líquido cefalorraquidiano em indivíduos com meningite por Enterovirus e, posteriormente, analisar suas relações por faixa etáriaMÉTODO: Foi realizado um estudo descritivo, com base nos dados do serviço de referência de coleta de líquido cefalorraquiano, localizado em São Paulo, Brasil. Totalizou-se em 202 indivíduos que apresentaram meningite por Enterovirus. Os dados foram analisados pelo teste de Shapiro-Wilk e Kruskal-Wallis (IC = 95%, p < 0,05) e representados pela mediana e percentil 25 e 75...


Meningitis is the leading infectious syndrome that affects the central nervous system, and most cases are caused by viral infections, mainly enterovirus. The clinical diagnosis for meningitis etiology still presents major challenges. The analysis of polymerase chain reaction (PCR), white blood cells, red blood cells, glucose, protein, and lactate in the cerebrospinal fluid (CSF) provides the first clues to the diagnosis. However, the reference values of some parameters can suffer changesOBJECTIVE: Analyze the laboratory parameters of CSF in patients with enterovirus meningitis, and then, theirrelationship by age groupMETHODS: A descriptive study was conducted based on data from a CSF reference service, located in São Paulo, Brazil, on 202 individuals who had enterovirus meningitis. Data was analysed by the Shapiro-Wilk and Kruskal-Wallis tests (CI = 95%, p < 0.05) and represented by the median and percentile 25 and 75, respectively...


Assuntos
Humanos , Masculino , Feminino , Líquido Cefalorraquidiano , Infecções por Enterovirus , Testes Laboratoriais , Microscopia , Meningite Asséptica/diagnóstico , Meningite Asséptica/terapia , Meningite Viral/diagnóstico , Meningite Viral/terapia , Reação em Cadeia da Polimerase , Ageismo , Viroses
5.
Artigo em Inglês | Index Psicologia - Periódicos técnico-científicos | ID: psi-65009

RESUMO

INTRODUCTION: Meningitis is the leading infectious syndrome that affects the central nervous system, and most cases are caused by viral infections, mainly enterovirus. The clinical diagnosis for meningitis etiology still presents major challenges. The analysis of polymerase chain reaction (PCR), white blood cells, red blood cells, glucose, protein, and lactate in the cerebrospinal fluid (CSF) provides the first clues to the diagnosis. However, the reference values of some parameters can suffer changes OBJECTIVE: Analyze the laboratory parameters of CSF in patients with enterovirus meningitis, and then, theirrelationship by age group METHODS: A descriptive study was conducted based on data from a CSF reference service, located in São Paulo, Brazil, on 202 individuals who had enterovirus meningitis. Data was analysed by the Shapiro-Wilk and Kruskal-Wallis tests (CI = 95%, p < 0.05) and represented by the median and percentile 25 and 75, respectively RESULTS: The cytological and biochemical parameters of the CSF shows us that proteins had median concentrations of 33.0mg/ dL, glucose of 57.0mg/dl, lactate of 19.0mg/dL and the leukocyte of 119.0 cells/mm³, with a predominance of lymphocytes (42%). It was found that age can cause cytological and biochemical changes in the parameters of CSF. Children younger than 2 years had a range percentage of neutrophils and monocytes different then children aged ≤ 2 and < 6 years, and aged ≤ 6 and < 10 years. The protein concentration range in CSF as well as glucose track can also change according to age CONCLUSION: The parameters of the CSF in patients with enteroviral meningitis showed similar median concentrations to those found in the literature. Age may lead to changes in cytological and biochemical parameters of CSF. CSF protein and glucose concentrations also change according to age.(AU)


INTRODUÇÃO: A meningite é a principal síndrome infecciosa que afeta o Sistema Nervoso Central, e grande parte dos casos são ocasionados por infecções virais, principalmente por enterovirus. O diagnóstico clínico para a verificação da etiologia da meningite ainda apresenta grandes desafios. As análises de Reação em Cadeia da Polimerase (PCR), leucócitos, hemácias, glicose, proteína e lactato no líquido cefalorraquidiano (LCR) fornecem os primeiros indícios para o diagnóstico. No entanto, os valores de referência de alguns parâmetros podem sofrer alterações OBJETIVO: Verificar parâmetros laboratoriais do líquido cefalorraquidiano em indivíduos com meningite por enterovirus e, posteriormente, analisar suas relações por faixa etária MÉTODO: Foi realizado um estudo descritivo, com base nos dados do serviço de referência de coleta de líquido cefalorraquiano, localizado em São Paulo, Brasil. Totalizaram 202 indivíduos que apresentaram meningite por enterovirus. Os dados foram analisados pelo teste de Shapiro-Wilk e Kruskal-Wallis (IC = 95%, p < 0,05) e representados pela mediana e percentil 25 e 75 RESULTADOS: Os parâmetros bioquímicos e citológicos do LCR apresentaram concentrações medianas de proteínas de 33.0 mg/dL, de glicose de 57.0 mg/dL e lactato de 19.0 mg/dL e dos leucócitos de 119.0 células/mm3, com predominância de linfócitos (42%). Verificou-se que a diferença etária pode levar as alterações nos parâmetros citológicos e bioquímicos do LCR. As crianças menores que dois anos apresentaram intervalo de percentual de neutrófilos e monócitos diferentes das crianças com faixa etária de = 2 e < 6 anos e de = 6 e < 10 anos. A faixa de concentração de proteína no LCR, assim como a faixa da glicose também podem sofrer alterações segundo a idade CONCLUSÃO: Os parâmetros bioquimiocitológicos do liquido cefalorraquidiano em indivíduos com meningite por enterovirus apresentaram concentrações medianas similares às encontradas na literatura. A diferença ...(AU)


Assuntos
Humanos , Meningite Viral/líquido cefalorraquidiano , Meningite Viral/virologia
6.
Neuropsychiatr Dis Treat ; 10: 613-8, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24748797

RESUMO

BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is characterized by decreased attention span, impulsiveness, and hyperactivity. Autonomic nervous system imbalance was previously described in this population. We aim to compare the autonomic function of children with ADHD and controls by analyzing heart rate variability (HRV). METHODS: Children rested in supine position with spontaneous breathing for 20 minutes. Heart rate was recorded beat by beat. HRV analysis was performed in the time and frequency domains and Poincaré plot. RESULTS: Twenty-eight children with ADHD (22 boys, aged 9.964 years) and 28 controls (15 boys, age 9.857 years) participated in this study. It was determined that the mean and standard deviation of indexes which indicate parasympathetic activity is higher in children with ADHD than in children without the disorder: high frequency in normalized units, 46.182 (14.159) versus 40.632 (12.247); root mean square of successive differences, 41.821 (17.834) versus 38.150 (18.357); differences between adjacent normal-to-normal intervals greater than 50 milliseconds, 199.75 (144.00) versus 127.46 (102.21) (P<0.05); percentage of differences between adjacent normal-to-normal intervals greater than 50 milliseconds, 23.957 (17.316) versus 16.211 (13.215); standard deviation of instantaneous beat-to-beat interval, 29.586 (12.622) versus 26.989 (12.983). CONCLUSION: Comparison of the autonomic function by analyzing HRV suggests an increase in the activity of the parasympathetic autonomic nervous systems in children with ADHD in relation to the control group.

7.
Int Arch Med ; 7(1): 1, 2014 Jan 03.
Artigo em Inglês | MEDLINE | ID: mdl-24387244

RESUMO

BACKGROUND: Although postural changes were already reported in blind adults, no previous study has investigated postural stability in blind children. Moreover, there are few studies which used a stabilometric instrument to measure postural balance. In this study we evaluated stabilometric paramaters in blind children. METHODS: We evaluated children between 7 to 12 years old, they were divided into two groups: Blind (n = 11) and age-matched control (n = 11) groups by using computerized stabilometry. The stabilometric examination was performed taking the gravity centers displacement of the individual projected into the platform. Thirthy seconds after the period in which this information was collected, the program defined a medium-pressure center, which was used to define x and y axes displacement and the distance between the pressure center and the platform center. Furthermore, the average sway rate and the body sway area were obtained by dividing the pressure center displacement and the time spent on the task; and by an ellipse function (95% percentille), respectively. Percentages of anterior, posterior, left and right feet weight also were calculated. Variables were compared by using the Student's t test for unpaired data. Significance level was considered for p <0.05. RESULTS: Displacement of the x axis (25.55 ± 9.851 vs. -3.545 ± 7.667; p <0.05) and average sway rate (19.18 ± 2.7 vs. -10.55 ± 1.003; p <0.001) were increased in the blind children group. Percentage of left foot weight was reduced (45.82 ± 2.017 vs. 52.36 ± 1.33; p <0.05) while percentage of right foot weight was increased (54.18 ± 2.17 vs. 47.64 ± 1.33; p <0.05) in blind children. Other variables did not show differences. CONCLUSIONS: Blind children present impaired stabilometric parameters.

8.
Rev. bras. crescimento desenvolv. hum ; 24(3): 274-281, 2014. tab
Artigo em Inglês | LILACS | ID: lil-744181

RESUMO

INTRODUÇÃO: a depressão, além de causar grande sofrimento psíquico, pode levar a prejuízos no desempenho acadêmico e nos relacionamentos sociais. OBJETIVO: estimar a prevalência de sintomas depressivos e sua associação com aspectos sociodemográficos e psicossociais em estudantes de medicina de uma região do Sertão Nordestino, Brasil. MÉTODO: apopulação foi constituída por 1024 estudantes do primeiro ao décimo segundo períodos do curso de medicina de duas escolas médicas do Cariri, Sertão Nordestino, Ceará, Brasil. Utilizou-se o questionário de caracterização sociodemográfica e o Inventário de Depressão de Beck versão II. RESULTADOS: a prevalência encontrada nessa população para o diagnóstico de depressão foi de 28,8%. 652 (63,7%) cumpriram com todos os protocolos para permanência na pesquisa. Apresentaram impacto negativo na saúde mental dos estudantes no modelo ajustado de regressão logística: sexo feminino OddsRatio ajustado (ORa) (IC95%): 1,83(1,19-2,82), saúde física razoável ORa (IC95%): 3,15(2,09-4,73), incerteza quanto ao futuro profissional ORa (IC95%): 2,97(1,65-5,34), desejo de mudar de curso ORa (IC95%):2,51(1,63-3,86), relacionamento social bom porém sem participação de atividades sociais ORa (IC95%): 1,96(1,27-3,04),dificuldades de relacionamento ORa (IC95%): 11,40(4,32-30,14) e raras atividades de lazer ORa (IC95%): 2,45(1,49-4,04) ou esporádicas atividades de lazer ORa (IC95%): 3,04(1,70-5,42. CONCLUSÃO: observou-se alta prevalência de depressão nos estudantes de medicina nesta região. Sexo feminino, saúde física razoável, incerteza quanto ao futuro profissional, desejo de mudar de curso, não participação de atividades sociais e/ou dificuldades de relacionamentos, esporádica ou rara atividade de lazer foram associados a maior chance de desenvolver sintomas depressivos.


INTRODUCTION: depression, besides causing great psychological distress, may lead to poor academic performance and social relationships. OBJECTIVE: to examine the prevalence of depressive symptoms in medical students from a northeastern region of Brazil. METHODS: the population comprised 1024 students from first to twelfth semesters of two medical schools in Cariri, Ceará, Brazil. We used the questionnaire on sociodemographic characteristics and the Beck Depression Inventory II version. RESULTS: the prevalence in this population for the diagnosis of depression was 28.8%.652 (63.7%) complied with all protocols to stay in research. After logistic regression, had a negative impact on studentsmental health: female Odds Ratio adjusted (ORa) (95% CI): 1.83 (1.19 to 2.82), reasonable physical health ORa (95% CI): 3.15 (2 0.09 to 4, 73), uncertainty about professional future ORa (95% CI): 2.97 (1.65 to 5.34), desire to change course ORa (95% CI): 2.51 (1.63 to 3.86), good social relationship but without participation in social activities ORa (95% CI): 1.96 (1.27 to 3.04), relationship difficulties ORa (95% CI): 11.40 (4.32 to 30.14) and rare leisure activities (95% CI): 2.45 (1.49 to 4.04) or eventual leisure activities ORa (95% CI): 3.04 (1.70 to 5.42). CONCLUSION: there was a high prevalence of depression among medical students in this region. Female, reasonable physical health, uncertainty over future career, desire to change course, do not participate in social activities and / or difficulties in relationships, sporadic or rare leisure activity were associated with increased risk of developing depressive symptoms.


Assuntos
Humanos , Masculino , Feminino , Depressão , Educação Médica , Transtornos de Aprendizagem , Prevalência , Estudantes de Medicina
9.
Rev. bras. crescimento desenvolv. hum ; 24(3): 274-281, 2014. tab
Artigo em Inglês | Index Psicologia - Periódicos técnico-científicos | ID: psi-65100

RESUMO

INTRODUÇÃO: a depressão, além de causar grande sofrimento psíquico, pode levar a prejuízos no desempenho acadêmico e nos relacionamentos sociais. OBJETIVO: estimar a prevalência de sintomas depressivos e sua associação com aspectos sociodemográficos e psicossociais em estudantes de medicina de uma região do Sertão Nordestino, Brasil. MÉTODO: apopulação foi constituída por 1024 estudantes do primeiro ao décimo segundo períodos do curso de medicina de duas escolas médicas do Cariri, Sertão Nordestino, Ceará, Brasil. Utilizou-se o questionário de caracterização sociodemográfica e o Inventário de Depressão de Beck versão II. RESULTADOS: a prevalência encontrada nessa população para o diagnóstico de depressão foi de 28,8%. 652 (63,7%) cumpriram com todos os protocolos para permanência na pesquisa. Apresentaram impacto negativo na saúde mental dos estudantes no modelo ajustado de regressão logística: sexo feminino OddsRatio ajustado (ORa) (IC95%): 1,83(1,19-2,82), saúde física razoável ORa (IC95%): 3,15(2,09-4,73), incerteza quanto ao futuro profissional ORa (IC95%): 2,97(1,65-5,34), desejo de mudar de curso ORa (IC95%):2,51(1,63-3,86), relacionamento social bom porém sem participação de atividades sociais ORa (IC95%): 1,96(1,27-3,04),dificuldades de relacionamento ORa (IC95%): 11,40(4,32-30,14) e raras atividades de lazer ORa (IC95%): 2,45(1,49-4,04) ou esporádicas atividades de lazer ORa (IC95%): 3,04(1,70-5,42. CONCLUSÃO: observou-se alta prevalência de depressão nos estudantes de medicina nesta região. Sexo feminino, saúde física razoável, incerteza quanto ao futuro profissional, desejo de mudar de curso, não participação de atividades sociais e/ou dificuldades de relacionamentos, esporádica ou rara atividade de lazer foram associados a maior chance de desenvolver sintomas depressivos.(AU)


INTRODUCTION: depression, besides causing great psychological distress, may lead to poor academic performance and social relationships. OBJECTIVE: to examine the prevalence of depressive symptoms in medical students from a northeastern region of Brazil. METHODS: the population comprised 1024 students from first to twelfth semesters of two medical schools in Cariri, Ceará, Brazil. We used the questionnaire on sociodemographic characteristics and the Beck Depression Inventory II version. RESULTS: the prevalence in this population for the diagnosis of depression was 28.8%.652 (63.7%) complied with all protocols to stay in research. After logistic regression, had a negative impact on studentsmental health: female Odds Ratio adjusted (ORa) (95% CI): 1.83 (1.19 to 2.82), reasonable physical health ORa (95% CI): 3.15 (2 0.09 to 4, 73), uncertainty about professional future ORa (95% CI): 2.97 (1.65 to 5.34), desire to change course ORa (95% CI): 2.51 (1.63 to 3.86), good social relationship but without participation in social activities ORa (95% CI): 1.96 (1.27 to 3.04), relationship difficulties ORa (95% CI): 11.40 (4.32 to 30.14) and rare leisure activities (95% CI): 2.45 (1.49 to 4.04) or eventual leisure activities ORa (95% CI): 3.04 (1.70 to 5.42). CONCLUSION: there was a high prevalence of depression among medical students in this region. Female, reasonable physical health, uncertainty over future career, desire to change course, do not participate in social activities and / or difficulties in relationships, sporadic or rare leisure activity were associated with increased risk of developing depressive symptoms.(AU)


Assuntos
Humanos , Masculino , Feminino , Estudantes de Medicina , Educação Médica , Depressão , Prevalência , Transtornos de Aprendizagem
10.
Int Arch Med ; 6(1): 22, 2013 May 08.
Artigo em Inglês | MEDLINE | ID: mdl-23656636

RESUMO

BACKGROUND: Autism is a disorder characterized by pervasive social and communicative impairments, repetitive and stereotyped behaviors and restricted interests. Its causes and effects have been researched from various neurocognitive theoretical perspectives and with the aid of neuroimaging technology. We aimed to describe biopsychosocial processes characteristic of the Autism Spectrum Disorders. METHOD: Literature review using Medline and Scopus databases published between 2001 and 2011, with the keywords "autism", "theory of mind", "executive functions", "central coherence" and "fMRI". RESULTS: The studies found were plotted and organized into tables and an explanatory diagram of the main findings was produced. CONCLUSIONS: The most popular neurocognitive theories are still unable to fully explain the characteristics of the complications that autistic spectrum disorder causes to the quality of life of individuals living with autism. The association of clinical research and neuroimaging may contribute to a better understanding of the functioning of the brain affected by the disorder.

11.
Int Arch Med ; 6(1): 15, 2013 Apr 24.
Artigo em Inglês | MEDLINE | ID: mdl-23618314

RESUMO

BACKGROUND: The time synchronization is a very important ability for the acquisition and performance of motor skills that generate the need to adapt the actions of body segments to external events of the environment that are changing their position in space. Down Syndrome (DS) individuals may present some deficits to perform tasks with synchronization demand. We aimed to investigate the performance of individuals with DS in a simple Coincident Timing task. METHOD: 32 individuals were divided into 2 groups: the Down syndrome group (DSG) comprised of 16 individuals with average age of 20 (+/- 5 years old), and a control group (CG) comprised of 16 individuals of the same age. All individuals performed the Simple Timing (ST) task and their performance was measured in milliseconds. The study was conducted in a single phase with the execution of 20 consecutive trials for each participant. RESULTS: There was a significant difference in the intergroup analysis for the accuracy adjustment - Absolute Error (Z = 3.656, p = 0.001); and for the performance consistence - Variable Error (Z = 2.939, p = 0.003). CONCLUSION: DS individuals have more difficulty in integrating the motor action to an external stimulus and they also present more inconsistence in performance. Both groups presented the same tendency to delay their motor responses.

12.
Int Arch Med ; 6(1): 11, 2013 Mar 07.
Artigo em Inglês | MEDLINE | ID: mdl-23497654

RESUMO

BACKGROUND: The literature has already demonstrated that cigarette influences the cardiovascular system. In this study, we performed a literature review in order to investigate the relationship between sidestream cigarette smoke (SSCS) and cardiac autonomic regulation. METHODS: Searches were performed on Medline, SciELO, Lilacs and Cochrane databases using the crossing between the key-words: "cigarette smoking", "autonomic nervous system", "air pollution" and "heart rate variability". RESULTS: The selected studies indicated that SSCS exposure affects the sympathetic and parasympathetic responses to changes in arterial blood pressure. Moreover, heart rate responses to environmental tobacco smoke are increased in smokers compared to non-smokers. The mechanism involved on this process suggest increased oxidative stress in brainstem areas that regulate the cardiovascular system. CONCLUSION: Further studies are necessary to add new elements in the literature to improve new therapies to treat cardiovascular disorders in subjects exposed to sidestream cigarette smoke.

13.
Int Arch Med ; 6(1): 6, 2013 Feb 18.
Artigo em Inglês | MEDLINE | ID: mdl-23418821

RESUMO

BACKGROUND: Radiotherapy is an important tool in the control of pain in patients with spinal metastatic disease. We aimed to evaluate pain and of quality of life of patients with spinal metastatic disease undergoing radiotherapy with supportive treatment. METHODS: The study enrolled 30 patients. From January 2008 to January 2010, patients selection included those treated with a 20 Gy tumour dose in five fractions. Patients completed the visual analogue scale for pain assessment and the SF-36 questionnaire for quality of life assessment. RESULTS: The most frequent primary sites were breast, multiple myeloma, prostate and lymphoma. It was found that 14 spinal metastatic disease patients (46.66%) had restricted involvement of three or fewer vertebrae, while 16 patients (53.33%) had cases involving more than three vertebrae. The data from the visual analogue scale evaluation of pain showed that the average initial score was 5.7 points, the value 30 days after the end of radiotherapy was 4.60 points and the average value 6 months after treatment was 4.25 points. Notably, this final value was 25.43% lower than the value from the initial analysis. With regard to the quality of life evaluation, only the values for the functional capability and social aspects categories of the questionnaire showed significant improvement. CONCLUSION: Radiotherapy with supportive treatment appears to be an important tool for the treatment of pain in patients with spinal metastatic disease.

14.
Int Arch Med ; 4: 37, 2011 Oct 26.
Artigo em Inglês | MEDLINE | ID: mdl-22029840

RESUMO

BACKGROUND: We aimed to evaluate the effects of chest and motor physiotherapy treatment on hemodynamic variables in preterm newborns with respiratory distress syndrome. METHODS: We evaluated heart rate (HR), respiratory rate (RR), systolic (SAP), mean (MAP) and diastolic arterial pressure (DAP), temperature and oxygen saturation (SO2%) in 44 newborns with respiratory distress syndrome. We compared all variables between before physiotherapy treatment vs. after the last physiotherapy treatment. Newborns were treated during 11 days. Variables were measured 2 minutes before and 5 minutes after each physiotherapy treatment. We applied paired Student t test to compare variables between the two periods. RESULTS: HR (148.5 ± 8.5 bpm vs. 137.1 ± 6.8 bpm - p < 0.001), SAP (72.3 ± 11.3 mmHg vs. 63.6 ± 6.7 mmHg - p = 0.001) and MAP (57.5 ± 12 mmHg vs. 47.7 ± 5.8 mmHg - p = 0.001) were significantly reduced after 11 days of physiotherapy treatment compared to before the first session. There were no significant changes regarding RR, temperature, DAP and SO2%. CONCLUSIONS: Chest and motor physiotherapy improved cardiovascular parameters in respiratory distress syndrome newborns.

15.
Nutr J ; 10: 43, 2011 May 08.
Artigo em Inglês | MEDLINE | ID: mdl-21549003

RESUMO

BACKGROUND: We evaluated growth and nutritional status of preschool children between 2 and 6 years old from low income families from 14 daycare centers. METHODS: Cross-sectional study with 1544 children from daycare centers of Santo Andre, Brazil. Body weight (W), height (H) and body mass index (BMI) were classified according to the 2000 National Center for Health Statistics (CDC/NCHS). Cutoff points for nutritional disorders: -2 z scores and 2.5 and 10 percentiles for malnutrition risk, 85 to 95 percentile for overweight and above BMI 95 percentile for obesity. Stepwise Forward Regression method was used including age, gender, birth weight, breastfeeding duration, age of mother at birth and period of time they attended the daycare center. RESULTS: Children presented mean z scores of H, W and BMI above the median of the CDC/NCHS reference. Girls were taller and heavier than boys, while we observed similar BMI between both genders. The z scores tended to rise with age. A Pearson Coefficient of Correlation of 0.89 for W, 0.93 for H and 0.95 for BMI was documented indicating positive association of age with weight, height and BMI. The frequency of children below -2 z scores was lower than expected: 1.5% for W, 1.75% for H and 0% for BMI, which suggests that there were no malnourished children. The other extremity of the distribution evidenced prevalence of overweight and obesity of 16.8% and 10.8%, respectively. CONCLUSION: Low income preschool children are in an advanced stage of nutritional transition with a high prevalence of overweight.


Assuntos
Transtornos da Nutrição Infantil/epidemiologia , Estado Nutricional , Obesidade/epidemiologia , Pobreza , Índice de Massa Corporal , Peso Corporal , Brasil , Criança , Transtornos da Nutrição Infantil/economia , Fenômenos Fisiológicos da Nutrição Infantil , Pré-Escolar , Estudos Transversais , Feminino , Humanos , Modelos Logísticos , Masculino , Estudos Multicêntricos como Assunto , National Center for Health Statistics (U.S.) , Obesidade/economia , Prevalência , Instituições Acadêmicas , Estados Unidos/epidemiologia
16.
Nutr Metab (Lond) ; 7: 63, 2010 Jul 23.
Artigo em Inglês | MEDLINE | ID: mdl-20653967

RESUMO

BACKGROUND: Little is known with respect to the metabolic response and the requirements of infected newborns. Moreover, the nutritional needs and particularly the energy metabolism of newborns with sepsis are controversial matter. In this investigation we aimed to evaluate the rest energy expenditure (REE) of newborns with bacterial sepsis during the acute and the recovery phases. METHODS: We studied nineteen neonates (27.3 +/- 17.2 days old) with bacterial sepsis during the acute phase and recovery of their illness. REE was determined by indirect calorimetry and VO2 and VCO2 measured by gas chromatography. RESULTS: REE significantly increased from 49.4 +/- 13.1 kcal/kg/day during the acute to 68.3 +/- 10.9 kcal/kg/day during recovery phase of sepsis (P < 0.01). Similarly, VO2 (7.4 +/- 1.9 vs 10 +/- 1.5 ml/kg/min) and VCO2 (5.1 +/- 1.7 vs 7.4 +/- 1.5 ml/kg/min) were also increased during the course of the disease (P < 0.01). CONCLUSION: REE was increased during recovery compared to the sepsis phase. REE of septic newborns should be calculated on individualized basis, bearing in mind their metabolic capabilities.

17.
Rev. CEFAC ; 8(4): 441-455, out.-dez 2006. tab, graf
Artigo em Português | LILACS | ID: lil-439821

RESUMO

Objetivos: caracterizar a população com Transtornos de Déficit de Atenção/Hiperatividade (TDAH);levantar prevalência de Transtornos de Aprendizagem (TA) e presença de respiração oral e verificarpossíveis associações. Métodos: foram estudados 77 pacientes do Serviço Ambulatorial deNeurodificuldades da Faculdade de Medicina ABC com diagnósticos de TA. Protocolos adaptadosforam utilizados para avaliação respiratória. Os subtipos de TDAH foram classificados pelo DSM-IV,sendo os pacientes agrupados em tipos: 1 (desatento), 2 (hiperativo-impulsivo) e 3 (combinado), presença/ausência de TA e modos respiratórios nasal, oral e oronasal. Foram utilizados: Teste de Igualdadede Duas Proporções, ANOVA e Técnica de Intervalo de Confiança para Proporção/Média. Resultados:houve prevalência de TDAH no gênero masculino, subtipo combinado, faixa etária infantil e 1ºgrau escolar. Observou-se alta ocorrência de TA (62,3%) com queixa de dificuldade escolar (87%).Houve significância estatística para presença de TA, dificuldade escolar e nenhuma repetência (61%).Houve alta ocorrência de respiração alterada (71,4%), que em associação ao TA foi de 41,6%. Houvepredominância de TA e respiração oronasal para gêneros e tipos de TDAH. O tipo 1 foi mais velho emidade média (12,4 anos) do que Tipo 3 (10,63 anos). Conclusões: o TDAH acometeu preferencialmentemeninos entre 7 e 13 anos, tipo 3, com alta prevalência e comorbidade com TA em associação arespiração oronasal. Houve correlação entre queixa de dificuldade escolar e TA; houve associaçãoentre TDAH, baixo rendimento escolar e presença de respiração oronasal devido à alta presença decomorbidade com TA, independente do gênero, idade ou subtipo de TDAH.


Purpose: to characterize the population with ADHD diagnoses; bring up prevalence of learning disabilities(LD) and presence of mouth breathing and verify likely association. Methods: 77 subjects of theNeurological Outpatient Clinic at ABC Medicine University were evaluated with LD diagnoses. Adaptedprotocols were used for respiratory evaluation. Subtypes of ADHD were classified by DSM-IV. Thus,the subjects were grouped in ADHD subtypes 1 (inattentive), 2 (hyperactivity / impulsive) and 3 (combined);LD presence / absence; and nasal, mouth breathing and mixed respiratory modes. “Dual ProportionEquality Test”, “ANOVA” and “Confidence Interval Technique for Proportion / Average” were used. Results:ADHD prevalence was noted in men, ADHD combined subtype, children’s of elementary and intermediateschool. There was high occurrence of LD (62.3%) with complaint of school difficulties (87%). There wasstatistical difference for LD presence, school difficulties and not repeater (61%). There was high occurrenceof altered respiration (71.4%) which in association with LD, it was 41.6%. There was LD and mixedrespiratory advantage for gender and ADHD types. Type 1 was older in average age (12.4 years old)than type 3 (10.63). Conclusion: ADHD appeared rather in boys among 7 and 13-year old, type 3 withhigh prevalence and comorbidity with LD in association with mixed respiratory mode. Complaint aboutschool difficulties showed correlation with LD. There was association among ADHD, low school efficiencyand presence of mixed respiratory due to high appearance of comorbidity with LD, regardless of gender,age or ADHD subtype.


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Respiração Bucal/epidemiologia , Transtorno do Deficit de Atenção com Hiperatividade/epidemiologia , Transtornos de Aprendizagem/epidemiologia , Distribuição por Idade , Fatores Etários , Análise de Variância , Brasil/epidemiologia , Comorbidade , Intervalos de Confiança , Escolaridade , Incidência , Prevalência , Taxas, Razões e Proporções , Fatores de Risco , Distribuição por Sexo , Fatores Sexuais , Síndrome , Baixo Rendimento Escolar
18.
RBM rev. bras. med ; 60(4): 179-184, abr. 2003. graf
Artigo em Português | LILACS | ID: lil-344739

RESUMO

Este trabalho tem como objetivo esclarecer aos profissionais envolvidos com o tratamento de pacientes com paralisia infantil sobre a toxina botulínica, seus possíveis efeitos colaterais, alguns critérios para selecionar o paciente e como devem ser feitas as aplicaçöes. Através de revisäo bibliográfica, concluímos que o uso localizazdo da TBA já é consagrado e muito utilizado. Entretanto, a indicaçäo desta droga para grandes musculares, como no tratamento das alteraçöes motoras secundárias a paralisia cerebral, ainda é pouco conhecida. Mesmo porque, a maioria dos trabalhos que estudam este tratamento se atém em tratar uma deformidade específica de uma doença generalizada como, por exemplo, o uso desta toxina para tratar o "pé eqüino". A partir desta pesquisa e da observaçäo de consultas e aplicaçöes de TBA nos ambulatórios da Associaçäo de Assistência à criança DEeficiente (AACD) concluímos que näo é possível tratar todas as seqüelas desta enfermidade. Contudo, é viável melhorar a qualidade de vida destes pacientes com paenas algumas aplicaçöes, ,afinal este tratamento permite uma nelhor higienizaçäo, facilitaçäo da fisioterapia, ,além de diminuir a dor causada pela espasticidade.Porém, é necessário muito critério no momento de selecionar este paciente, visto que esta terapia é muito cara, näo definitiva e pode ser dolorosa.


Assuntos
Humanos , Paralisia Cerebral , Toxinas Botulínicas Tipo A/administração & dosagem , Toxinas Botulínicas Tipo A/efeitos adversos , Toxinas Botulínicas Tipo A/farmacologia , Toxinas Botulínicas Tipo A/uso terapêutico
19.
Neurobiologia ; 57(1): 31-4, jan.-mar. 1994. tab
Artigo em Português | LILACS | ID: lil-154568

RESUMO

O objetivo foi avaliar a ocorrência de sonilóquio em uma populaçäo de pacientes portadores de deficiência mental (DM). Foi aplicado questionário sobre distúrbios do sono, padronizado, a 337 pacientes com DM, em sua maioria abaixo dos 15 anos de idade, sendo 65 por cento do sexo masculino e 35 por cento feminino. Verificou-se maior encontro de pacientes com sonilóquio abaixo dos 15 anos de idade. Dentre os acometidos, a maior frequência deste comportamento ocorria até os 20 anos de idade. Nesta populaçäo com DM, os índices de ocorrência de sonilóquio foram marcadamente menores, quando comparados a populaçöes normais


Assuntos
Deficiência Intelectual , Transtornos do Sono-Vigília
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA