Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 39
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
J Agric Food Chem ; 68(4): 1091-1100, 2020 Jan 29.
Artigo em Inglês | MEDLINE | ID: mdl-31896257

RESUMO

The physical structure of type 1 resistant starch (RS 1) could influence the metabolite production and stimulate the growth of specific bacteria in the human colon. In the present study, we isolated intact cotyledon cells from pinto bean seeds as whole pulse food and RS 1 model and obtained a series of cell wall integrities through controlled enzymolysis. In vitro human fecal fermentation performance and microbiota responses were tested, and we reported that the cell wall integrity controls the in vitro fecal fermentation rate of heat-treated pinto bean cells. The concentration of butyrate produced by pinto bean cell fermentation enhanced with weakened cell wall integrity, and certain beneficial bacterial groups such as Blautia and Roseburia genera were remarkably promoted by pinto bean cells with damaged cell wall integrity. However, the intact cell sample had a shape more similar to microbiota composition with the purified cell wall polysaccharides, rather than the damaged cells.

2.
Wei Sheng Yan Jiu ; 48(6): 945-952, 2019 Nov.
Artigo em Chinês | MEDLINE | ID: mdl-31875820

RESUMO

OBJECTIVE: To understand the epidemiological characteristics and risk factors of dyslipidemia in adult residents of Jiangsu Province in 2014. METHODS: A total of 8677 permanent residents over 18 years old were selected from 12 monitoring sites in Jiangsu Province in 2014 by multi-stage stratified cluster random sampling and were enrolled for questionnaire survey, physic examination and biochemical tests. RESULTS: Totally, 8299 cases were analyzed including 3732 males(45. 0%) and 4567 females(55. 0%). The rate of dyslipidemia was 38. 2%(standardized prevalence rate was38. 5%). Among the 8299 cases, 25. 8% had high TG(standardized rate was 25. 9%), 13. 2% had low HDL-C(standardized rate was 13. 4%), 6. 0% had high TC(standardized rate was 5. 9%). With the increase of age, the prevalence of dyslipidemia in males showed a downward trend(P<0. 05), and the dyslipidemia in females showed an increasing trend(P<0. 05). The prevalence of dyslipidemia in urban and rural adults was42. 9% and 36. 9%. The Logistic multivariate analysis showed that heavy physical and other types of labor were protective factors for dyslipidemia(OR = 0. 422 and 0. 749). Primary school education or above, occupational labor of medium type, overweight and obesity, central obesity were risk factors for dyslipidemia. Hypertension, diabetes, stroke were positively correlated with dyslipidemia(OR = 1. 045, 1. 927, 1. 927 and 1. 501). CONCLUSION: The prevalence of dyslipidemia in adults in Jiangsu Province is on the rise. Hyperlipidemia and low HDL-C are the main forms of dyslipidemia in Jiangsu Province.


Assuntos
Diabetes Mellitus , Dislipidemias , Adolescente , Adulto , China , Feminino , Humanos , Masculino , Obesidade , Sobrepeso , Prevalência , Fatores de Risco , Adulto Jovem
3.
BMC Cancer ; 19(1): 1218, 2019 Dec 16.
Artigo em Inglês | MEDLINE | ID: mdl-31842816

RESUMO

BACKGROUND: Consumption of moldy food has previously been identified as a risk factor for esophageal squamous cell carcinoma (ESCC) in high-risk countries; however, what contributing roles these dietary carcinogenic mycotoxins play in the etiology of ESCC are largely unknown. METHODS: A mycotoxin biomarker-incorporated, population-based case-control study was performed in Huaian area, Jiangsu Province, one of the two high-risk areas in China. Exposure biomarkers of aflatoxins (AF) and fumonisins (FN) were quantitatively analyzed using HPLC-fluorescence techniques. RESULTS: Among the cases (n = 190), the median levels of AF biomarker, serum AFB1-lysine adduct, and FN biomarker, urinary FB1, were 1.77 pg/mg albumin and 176.13 pg/mg creatinine, respectively. Among the controls (n = 380), the median levels of AFB1-lysine adduct and urinary FB1 were 1.49 pg/mg albumin and 56.92 pg/mg creatinine, respectively. These mycotoxin exposure biomarker levels were significantly higher in cases as compared to controls (p <  0.05 and 0.01, respectively). An increased risk to ESCC was associated with exposure to both AFB1 and FB1 (p <  0.001 for both). CONCLUSIONS: Mycotoxin exposure, especially to AFB1 and FB1, was associated with the risk of ESCC, and a greater-than-additive interaction between co-exposures to these two mycotoxins may contribute to the increased risk of ESCC in Huaian area, China.

4.
Cancer Cell Int ; 19: 288, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31754346

RESUMO

Background: The study aimed to explore the associations between the interactions of serum vitamin B2 or B12 levels, aberrant DNA methylation of p16 or p53 and MTHFR C677T polymorphism and the risks of esophageal squamous cell carcinoma (ESCC) and esophageal precancerous lesion (EPL). Methods: 200 ESCC cases, 200 EPL cases and 200 normal controls were matched by age (± 2 years) and gender. Serum vitamin B2 and B12 levels, MTHFR C677T genetic polymorphisms and the methylation status of genes were assessed. Chi square test, one-way analysis of variance and binary logistic regression were performed. Results: The lowest quartile of both serum vitamin B2 and B12 with TT genotype showed significant increased EPL risk (OR = 4.91, 95% CI 1.31-18.35; OR = 6.88, 95% CI 1.10-42.80). The highest quartile of both serum vitamin B2 and B12 with CC genotype showed significant decreased ESCC risk (OR = 0.16, 95% CI 0.04-0.60; OR = 0.10, 95% CI 0.02-0.46). The ORs of p16 methylation for genotype CT and TT were 1.98 (95% CI 1.01-3.89) and 17.79 (95% CI 2.26-140.22) in EPL, 4.86 (95% CI 2.48-9.50) and 20.40 (95% CI 2.53-164.81) in ESCC, respectively. Similarly, p53 methylation with genotype TT was associated with increased EPL and ESCC risks (OR = 13.28, 95% CI 1.67-105.70; OR = 15.24, 95% CI 1.90-122.62). Conclusions: The MTHFR C677T genotype and serum vitamin B2 or B12 levels may interact in ways which associated with the EPL and ESCC risks. The gene-gene interaction suggested that aberrant DNA methyaltion of either p16 or p53 combined with T alleles of MTHFR was associated with increased risks of both EPL and ESCC.

5.
J Agric Food Chem ; 67(49): 13728-13736, 2019 Dec 11.
Artigo em Inglês | MEDLINE | ID: mdl-31617357

RESUMO

A slow fermentation rate of dietary fiber could result in a steady metabolite production release and even distribution in the entire colon, increasing the likelihood of meeting the energy requirements of the distal colon. In the present study, we modulated the fermentation rate in an in vitro human fecal fermentation model by applying chemical cross-linking modification to a type 2 resistant starch [i.e., high-amylose maize starch (HAMS)]. Cross-linking modification decreased the gas production (an indicator of the fermentation rate) of HAMS throughout the whole fermentation progress. The butyrate production rate of cross-linked starches decreased gradually with the increase of the cross-linking degree. Certain beneficial gut microbiota such as genera of Blautia and Clostridiales members were remarkably promoted by starches with low and medium cross-linking degrees, whereas HAMS with a high cross-linking degree obviously promoted the abundance of Bacteroides uniformis and Ruminococcus bromii. This finding reveals that cross-linking modification effectively controls the fermentation rate and highlights the modulation metabolite profiles and gut microbiota composition through chemical modification.


Assuntos
Amilose/química , Fezes/microbiologia , Microbioma Gastrointestinal , Zea mays/metabolismo , Amilose/metabolismo , Bactérias/classificação , Bactérias/genética , Bactérias/isolamento & purificação , Bactérias/metabolismo , Ácidos Graxos Voláteis/metabolismo , Feminino , Fermentação , Humanos , Intestino Grosso/metabolismo , Intestino Grosso/microbiologia , Masculino , Zea mays/química
6.
Carbohydr Polym ; 223: 115069, 2019 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-31426996

RESUMO

Resistant starch (RS) acylated with propionate groups is of particular interest in terms of their capacity to deliver specific short-chain fatty acids (SCFAs) to the colon with health benefits. In the present study, we fabricated propionylated high-amylose maize starches with different degrees of substitution (DS), and monitored the in vitro human fecal fermentation profiles. Propionylated modification did not change the slow gas production properties of high-amylose maize starch throughout the whole fermentation period. The final concentration of propionate (13.68-21.10 mM) produced by propionylated starch fermentation enhanced gradually with increase of DS value, resulting from the release of introduced propionyl groups. Certain beneficial gut microbiota such as Roseburia, and Blautia were obviously promoted, suggesting that propionylated starch could regulate the composition of gut microbiota. The results may facilitate the design and manufacture of functional food products with the aim of improving colonic health.


Assuntos
Amilose/metabolismo , Fezes/microbiologia , Fermentação , Microbioma Gastrointestinal/fisiologia , Propionatos/metabolismo , Zea mays/química , Adulto , Amilose/química , Bactérias/metabolismo , Butiratos/metabolismo , Humanos , Estrutura Molecular , Propionatos/química , Adulto Jovem
7.
J Agric Food Chem ; 67(29): 8212-8226, 2019 Jul 24.
Artigo em Inglês | MEDLINE | ID: mdl-31309827

RESUMO

The factors that determine the digestion rate of starches were revealed using different forms of starches and a mixture of α-amylase and amyloglucosidase. Gelatinized starch samples with a degree of gelatinization (DG) from 12.2 to 100% for potato starch and from 7.1 to 100% for lotus seed starch were obtained. With an increasing DG, the short- and long-range molecular orders of both starches were disrupted progressively. The first-order digestion rate constant (k) of both starches increased with an increasing DG, although the positive linear relationships between DG and k differed (R2 = 0.87 for potato starch, and R2 = 0.74 for lotus seed starch). The mean fluorescence intensity showed a positive linear correlation with DG, which was strong for potato starch (R2 = 0.99) and relatively weaker for lotus seed starch (R2 = 0.54). These results indicated that DG is a major determinant for the digestion rate of potato starch and lotus seed starch and that the access/binding of enzymes to starch was the main rate-limiting factor for digestion of starches.


Assuntos
Glucana 1,4-alfa-Glucosidase/química , Lotus/química , Extratos Vegetais/química , Solanum tuberosum/química , Amido/química , alfa-Amilases/química , Biocatálise , Digestão , Hidrólise , Cinética , Sementes/química
8.
Opt Express ; 27(10): 14173-14183, 2019 May 13.
Artigo em Inglês | MEDLINE | ID: mdl-31163870

RESUMO

Multi-channel modelocked lasers and their design have attracted much attention. Here, we use the Swift-Hohenberg equation to study dual-channel simultaneous modelocking (DSML) in a fiber laser. When a quartic filter is added to the laser cavity, the stable dual-channel simultaneous modelocking can be obtained for a given filter bandwidth when frequency separation, ωs, is less than a calculated threshold, ωth. When ωs>ωth, a multipulsing instability occurs. We use a linear stability analysis to determine the limit that the multi-pulsing instability imposes on DSML, and we propose a cavity design that avoids the multi-pulsing instability.

9.
Cancer Prev Res (Phila) ; 12(7): 449-462, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31040152

RESUMO

Better understanding of esophageal precancerous lesions (EPL) can inform prevention strategies for esophageal squamous cell carcinoma (ESCC). Here, a cross-sectional epidemiologic study based on the Early Diagnosis and Early Treatment Project of Esophageal Cancer database from 2011 to 2017 was performed to fully investigate and characterize the epidemiology of EPL in rural Huai'an District. Data of 11,518 participants ages 35-75 years were collected through face-to-face interviews by questionnaire. Participants underwent a routine endoscopy examination, tissues were biopsied, and diagnosed according to the histologic criteria of dysplasia. Unconditional univariate and multivariate logistic regression analyses were performed to obtain crude and adjusted odds ratios and corresponding 95% confidence intervals, respectively. A total of 667 subjects were diagnosed with EPL. Factors associated with an increased risk of EPL included: drinking shallow well water and surface water, irregular diet, excessive smoking, exposure to secondhand smoke, consumption of corn, corn flour, pickled food, fried food, and hot food, and having a history of digestive system diseases. In addition, liquor use, but not other alcohol types, contributed to risk of EPL. Consumption of deep well water and vegetables, fruits, and animal livers were associated with lower EPL risk. This study suggested a completely distinct pattern that alcohol use plays only a minor role in EPL and excessive tobacco use shows a significant association in rural Huai'an District, while eating habits and environmental exposure may be the dominant factors. This work may be promising to provide scientific evidence to support primary prevention of ESCC in this region.

10.
Opt Express ; 27(3): 3717-3730, 2019 Feb 04.
Artigo em Inglês | MEDLINE | ID: mdl-30732387

RESUMO

We describe a procedure to calculate the impulse response and phase noise of high-current photodetectors using the drift-diffusion equations while avoiding computationally expensive Monte Carlo simulations. We apply this procedure to a modified uni-traveling-carrier (MUTC) photodetector. In our approach, we first use the full drift-diffusion equations to calculate the steady-state photodetector parameters. We then perturb the generation rate as a function of time to calculate the impulse response. We next calculate the fundamental shot noise limit and cut-off frequency of the device. We find the contributions of the electron, hole, and displacement currents. We calculate the phase noise of an MUTC photodetector. We find good agreement with experimental and Monte Carlo simulation results. We show that phase noise is minimized by having an impulse response with a tail that is as small as possible. Since, our approach is much faster computationally than Monte Carlo simulations, we are able to carry out a broad parameter study to optimize the device performance. We propose a new optimized structure with less phase noise and reduced nonlinearity.

11.
Food Res Int ; 116: 20-29, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30716937

RESUMO

Lycium barbarum polysaccharide (LBP), as one bioactive macromolecular abstracted from goji berry, has shown an abundance of potential function. The present study aimed to evaluate the metabolic effects of LBP on the urine and liver metabolomics on a high-fat diet and streptozotocin-induced diabetic rat model. After 8 weeks of high-fat diet and streptozotocin induction of diabetes, 24 diabetic rats were randomly allocated to the diabetic control (DC) group, LBP low, moderate, and high dosage (LBP-L, LBP-M, LBP-H) groups and 6 non-diabetic rats were established as the non-diabetic control (NDC) group for 30 days' intervention. Metabolomics was performed on liver and urine. LBP positively regulated fasting blood glucose, hemoglobin-A1c, homeostasis model assessment for insulin resistance, liver glycogen and SOD levels significantly, as compared to the DC group. Liver metabolomics showed higher levels of myo-inositol and lower levels of L-malic acid, fumaric acid, D-arabitol, L-allothreonine 1, xylitol, O-phosphorylethanolamine, ribitol, 5-methoxytryptamine 2 and digitoxose 2 in the LBP-H group vs. the DC group, which indicates that LBP may regulate the citrate cycle, alanine, aspartate and glutamate metabolism, glyoxylate and dicarboxylate metabolism. Urine metabolomics showed increased levels of creatinine, D-galacturonic acid 2, 2,3-dihydroxybutyric acid and citric acid, and decreased levels of methylmalonic acid, benzoic acid and xylitol between the LBP-H and DC groups. The present study exhibited the effects of LBP on the urine and liver metabolomics in a high-fat diet and streptozotocin-induced rat model, which not only provides a better understanding of the anti-diabetic effects of LBP but also supplies a useful database for further specific mechanism study.

12.
Int J Food Sci Nutr ; 70(3): 355-366, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30160543

RESUMO

The aim of this study is to investigate the effects of palm olein (POL), cocoa butter (CB) and extra virgin olive oil (EVOO) on the lipid profile and low-density lipoprotein subfractions in a young, healthy Chinese population. After screening, 72 subjects were randomly assigned to three groups, and an 18-week randomized crossover trial was conducted. The first phase was a 2-week run-in period, followed by three phases of the 4-week experimental periods with a 2-week washout period between experimental periods. Three groups of subjects alternately consumed a Chinese diet enriched with the different test oils. The various indices of subjects were collected before and after each experimental period. Sixty-seven subjects completed the study, and there were no significant differences in conventional indices amongst the three groups at the beginning of the three experimental periods (p > .05). Each test oil accounted for approximately 40% of total fat intake and approximately 11.3% of the total energy supply. After controlling for dietary interventions, only the serum triglyceride level of the POL-Diet was significantly lower than that of the EVOO-Diet (p = .034), and most indices did not significantly differ amongst the three test oil diets (p > .05). POL, CB and EVOO have almost identical effects on serum lipids.


Assuntos
Gorduras na Dieta/farmacologia , Lipídeos/sangue , Lipoproteínas LDL/sangue , Azeite de Oliva/farmacologia , Óleo de Palmeira/farmacologia , China , Estudos Cross-Over , Feminino , Humanos , Lipídeos/classificação , Lipoproteínas LDL/classificação , Masculino , Adulto Jovem
13.
Artigo em Inglês | MEDLINE | ID: mdl-30499751

RESUMO

The goal of this study was to find the relationship between dietary nitrite and risk of esophageal cancer, and determine the amount of nitrite intake to establish the oral highest daily intake to prevent the occurrence of esophageal cancer. Duplicate portions of three-consecutive-day diets were collected from 100 patients with esophageal precancerous lesions and 100 controls. The average nitrite daily intakes for esophageal precancerous lesions and normal people were 15.72 mg/d and 11.11 mg/d. The median nitrite daily intakes for cases and controls were 8.76 mg/d and 5.33 mg/d. Positive association was observed between the risk of esophageal precancerous lesions and dietary nitrite intake (p = 0.035). An increased risk of esophageal precancerous lesions was observed for cases or controls in the highest intake quartile of nitrite (highest vs. lowest quartile odds ratio (OR) = 2.256, 95% confidence interval (CI): 1.012-5.026). These results suggest that dietary nitrite intake may influence the risk of esophageal cancer; populations with high incidence of esophageal cancer should take control of nitrite intake as one of the measures to prevent esophageal cancer.


Assuntos
Inquéritos sobre Dietas , Dieta/efeitos adversos , Neoplasias Esofágicas/induzido quimicamente , Nitritos/administração & dosagem , Nitritos/efeitos adversos , Lesões Pré-Cancerosas/induzido quimicamente , Adulto , Idoso , Estudos de Casos e Controles , Neoplasias Esofágicas/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Lesões Pré-Cancerosas/patologia , Fatores de Risco
14.
Nutrients ; 10(11)2018 Nov 20.
Artigo em Inglês | MEDLINE | ID: mdl-30463386

RESUMO

The objective of this study is to investigate and compare the prevalence, knowledge, and attitudes of Chinese university students with respect to nutritional supplements. We conducted a cross-sectional study in several universities around China from January to December 2017, and enrolled a total of 8752 students. Of these, 4252 were medical students and 4500 were non-medical students. The use of nutritional supplements was reported by 58.9% in universities students, with a higher rate for medical students as compared to non-medical students. It was found 24.2% of participants had taken supplements in the past year. Medical students had a higher level of knowledge on nutritional supplements than non-medical students (p < 0.001). The most commonly used nutritional supplements were vitamin C, calcium, and vitamin B. Gender (p < 0.001), household income (p < 0.001), and health status (p < 0.001) were related to the nutritional supplement use after adjustment for related factors. In conclusion, in China, nutritional supplement use was found to be more common in medical students than those studying other disciplines, and was associated with sex, income, and health status. The attitude towards nutritional supplements by medical students was positive. Students' knowledge levels about nutritional supplements need to be improved.


Assuntos
Suplementos Nutricionais , Conhecimentos, Atitudes e Prática em Saúde , Estudantes de Medicina/psicologia , Estudantes/psicologia , Adulto , China , Estudos Transversais , Feminino , Nível de Saúde , Humanos , Renda , Masculino , Inquéritos e Questionários , Universidades , Adulto Jovem
16.
Nutr Metab (Lond) ; 15: 43, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29951108

RESUMO

Background: Until now, little research concerning the lipid-lowering and anti-obesity functions of garlic oil and onion oil has been performed. The objective of this study was to explore the effects of garlic oil and onion oil on serum lipid levels in hyperlipidemia model rats, to provide a scientific basis for the prevention of hyperlipidemia through a dietary approach, and to explore the potential health benefits of garlic and onion. Method: Ninety-six male Sprague-Dawley rats were randomly allocated into eight groups based on their body weight and serum levels of triglycerides (TG) and total cholesterol (TC). The rats received repeated oral administration of volatile oils extracted from garlic and onion for 60 days. Serum lipids and parameters of obesity were examined. Results: The volatile oils suppressed the HFD-induced body weight gain and tended to decrease adipose tissue weight. The oils decreased the levels of TG, TC and LDL-C and increased the serum level of HDL-C compared with the rats in the hyperlipidemia model groups (P < 0.05). The oils were also effective at improving the lipid profile and alleviating hepatic steatosis. Conclusion: Our results implied that garlic oil and onion oil have anti-obesity properties that can counteract the effects of an HFD on body weight, adipose tissue weight, and serum lipid profiles.

17.
Lipids Health Dis ; 17(1): 125, 2018 May 25.
Artigo em Inglês | MEDLINE | ID: mdl-29801502

RESUMO

BACKGROUND: The balance between n-6 and n-3 PUFAs is an important determinant in the risk for cardiovascular disease. The study was to investigate the influence of the n-6 and n-3 PUFAs ratio on the formation of THP-1 monocyte-derived foam cells and explore the probable mechanism of anti-atherosclerosis. METHODS: THP-1 monocyte cells were cultured with PMA and ox-LDL to establish a foam-cell model, while treated with different ratios of n-6 to n-3 PUFAs for 48 h. The cholesterol of foam cells was measured by a cholesterol assay kit. The levels of IL-6 and TNFα in supernatant were detected with ELISA methods. The expressions of CD36, ABCA1, ACAT1, PPARγ and LXRα mRNA were detected with real-time PCR. RESULTS: Compared with the foam cell model group, the low and middle ratio of n-6 to n-3 PUFAs groups decreased the intracellular concentration of cholesterol (P < 0.01), but the high n-6/n-3 PUFAs ratio did not. Fatty acids decreased the level of IL-6 and TNFα in supernatant in a ratio-dependent manner. Fatty acids treatment also decreased the expressions of CD36、ACTA1、PPARγ、LXRα mRNA in a ratio-dependent manner. CONCLUSIONS: Lowering the ratios of n-6 to n-3 PUFAs can decrease the secretion of inflammatory cytokines then reduce the expressions of CD36 and ACAT1 mRNA. As well, it can decrease the expressions of CD36 mRNA through the PPARγ pathway. This leads to less cholesterol ingestion into the cells and decreased synthesis of cholesteryl ester, which inhibits the formation of the foam cells, further preventing the occurrence and development of atherosclerosis.


Assuntos
Antígenos CD36/genética , Colesterol/metabolismo , Citocinas/metabolismo , Ácidos Graxos Ômega-3/farmacologia , Ácidos Graxos Ômega-6/farmacologia , Células Espumosas/metabolismo , PPAR gama/metabolismo , Aterosclerose/metabolismo , Antígenos CD36/metabolismo , Diferenciação Celular , Linhagem Celular , Células Espumosas/efeitos dos fármacos , Regulação da Expressão Gênica , Humanos , Inflamação , Interleucina-6/metabolismo , Monócitos/fisiologia , Transdução de Sinais , Fator de Necrose Tumoral alfa/metabolismo
18.
Asia Pac J Clin Nutr ; 27(3): 572-580, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29737804

RESUMO

BACKGROUND AND OBJECTIVES: As the most widely produced edible vegetable oil, palm oil is known as to contain a high level of saturated fatty acid, which was thought to adversely affect serum lipid profiles. However, recent studies have shown no influence or benefits of palm oil on serum lipids. The potential nutritional value of palm oil is attributed to the high mono-unsaturation at the crucial sn2-position of the oil's triacylglycerols, as with the so-called 'healthy' olive oil (OO). The aim of this study was to further test this hypothesis and evaluate the effects of consuming palm olein versus olive oil on serum lipid profiles in a Chinese population. METHODS AND STUDY DESIGN: In total, 120 participants were recruited from a spinnery in Yixing city and randomly divided into two groups (palm olein or olive oil) to conduct a 2×2 crossover trial for 2 months' intervention with 2-week washout periods. Each participant was provided 48 g of test oil per day. At the end of each period, anthropometry, and blood lipid indices were measured to determine the effects of palm olein and olive oil. RESULTS: Palm olein and olive oil consumption had no significantly different effect on BMI, on serum total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triacylglycerol (TG), Apo B, fasting glucose, or insulin concentrations (all p>0.05). CONCLUSIONS: In a dietary crossover trial, palm olein and olive oil had no recognisably different effects on body fatness or blood lipids in a healthy Chinese population.


Assuntos
Gorduras na Dieta/metabolismo , Lipídeos/sangue , Azeite de Oliva/metabolismo , Óleo de Palmeira/metabolismo , Adulto , China , Estudos Cross-Over , Dieta , Gorduras na Dieta/administração & dosagem , Método Duplo-Cego , Feminino , Voluntários Saudáveis , Humanos , Masculino , Pessoa de Meia-Idade , Azeite de Oliva/administração & dosagem , Óleo de Palmeira/administração & dosagem
19.
Opt Lett ; 42(12): 2362-2365, 2017 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-28614311

RESUMO

Passively mode-locked lasers with semiconductor saturable absorption mirrors are attractive comb sources due to their simplicity, excellent self-starting properties, and their environmental robustness. These lasers, however, can have an increased noise level and wake mode instabilities. Here, we investigate the wake mode dynamics in detail using a combination of evolutionary and dynamical methods. We describe the mode-locked pulse generation from noise when a stable pulse exists and the evolution of the wake mode instability when no stable pulse exists. We then calculate the dynamical spectrum of the mode-locked pulse, and we show that it has six discrete eigenmodes, two of which correspond to wake modes. The wake modes are unstable when the wake mode eigenvalues have a positive real part. We also show that even when the laser is stable, the wake modes lead to experimentally observed sidebands.

20.
Food Nutr Res ; 61(1): 1265324, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28326000

RESUMO

The antioxidant function of edible flowers have attracted increasing interest. However, information is lacking on the impact of edible flowers on oxidative injury including hypoxia-re-oxygenation and hyperlipidemia. The antioxidant activities of aqueous extracts from 12 Chinese edible flowers were assessed in four different antioxidant models, including total antioxidant capacity (TAC), oxygen radical absorbance capacity (ORAC), scavenging hydroxyl radical capacity (SHRC) and scavenging superoxide anion radical capacity (SSARC). Subsequently, the potential antioxidant effects on rat cardiac microvascular endothelial cells (rCMEC) treated with hypoxia-re-oxygenation and hyperlipidemia rats induced by high-fat diet were also evaluated. The highest TAC, ORAC, SHRC and SSARC were Lonicera japonica Thunb., Rosa rugosa Thunb., Chrysanthemum indicum L. and Rosa rugosa Thunb., respectively. Most aqueous extracts of edible flowers exhibited good antioxidant effects on injury of rCMEC induced by hypoxia-re-oxygenation. In addition, the aqueous extracts of Lonicera japonica Thunb., Carthamus tinctorius L., Magnolia officinalis Rehd. et Wils., Rosmarinus officinalis L. and Chrysanthemum morifolium Ramat. could suppress the build-up of oxidative stress by increasing serum superoxide dismutase, glutathion peroxidase, and reducing malonaldehyde concentration in hyperlipidemia rats. These findings provided scientific support for screening edible flowers as natural antioxidants and preventative treatments for oxidative stress-related diseases.

SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA