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J Food Sci ; 81(2): C317-23, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26720174


In this study, a pH-stat digestion model and a simulated in vitro digestion model were employed to evaluate the digestion degree of lipids depending on different acylglycerols and acyl chain length (that is, diacylglycerol [DAG] compared with soybean oil representing long-chain triacylglycerol compared with medium-chain triacylglycerol [MCT]). In the pH-stat digestion model, differences were observed among the digestion degrees of 3 oils using digestion rate (k), digestion half-time (t1/2 ), and digestion extent (Φmax). The results showed the digestion rate order was MCT > soybean oil > DAG. Accordingly, the order of digestion half-times was MCT < soybean oil < DAG. In simulated in vitro digestion model, digestion rates (k') and digestion half-times (t'1/2 ) were also obtained and the results showed a digestion rate order of MCT (k' = 0.068 min(-1) ) > soybean oil (k' = 0.037 min(-1) ) > DAG (k' = 0.024 min(-1) ). Consequently, the order of digestion half-times was MCT (t'1/2 = 10.20 min) < soybean oil (t'1/2 = 18.74 min) < DAG (t'1/2 = 29.08 min). The parameters obtained using the 2 models showed MCT was digested faster than soybean oil, and that soybean oil was digested faster than DAG.

Diglicerídeos/metabolismo , Glicerídeos/metabolismo , Óleo de Soja/metabolismo , Triglicerídeos/metabolismo , Digestão , Ácidos Graxos/metabolismo , Humanos , Concentração de Íons de Hidrogênio , Técnicas In Vitro , Metabolismo dos Lipídeos , Modelos Biológicos
J Food Sci ; 80(3): C510-4, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25678328


To compare the oxidative stability between diacylglycerol (DAG) oil and conventional triacylglycerol (TAG) oil (that is, soybean oil), the prepared stripped diacylglycerol oil (SDO) and soybean oil (SSBO) were stored at 60 °C in the dark for 144 h. During storage peroxide values (POVs), contents of aldehydes, unsaturated fatty acids were measured to evaluate the oxidative stabilities of the 2 oils. The results showed the content of C18:2, C18:3, and total unsaturated fatty acid decreased faster in DAG oil than in soybean oil, whereas the decreased rate of C18:1 was similar in 2 oils. Also, both rate constants (K1 and K2) obtained from POV (K1 ) and total aldehydes (K2 ) indicated that DAG oil (K1 = 3.22 mmol/mol FA h(-1) , K2 = 0.023 h(-1)) was oxidized more rapidly than soybean oil (K1 = 2.56 mmol/mol FA h(-1) , K2 = 0.021 h(-1)), which was mainly due to the difference of acylglycerol composition of the 2 oils along with higher C18:3 (9.6%) in SDO than SSBO (5.7%). It is concluded that DAG was more easily oxidized than soybean oil at 60 °C in the dark for 144 h.

Diglicerídeos/análise , Peroxidação de Lipídeos , Óleos/análise , Óleo de Soja/análise , Triglicerídeos/análise , Dieta , Glicerídeos/análise , Humanos , Oxirredução
Spine J ; 13(11): 1538-43, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23932822


BACKGROUND CONTEXT: Posterior occipitocervical fusion techniques have been previously described; however, traditional open anterior approaches are plagued by exposure difficulty. A minimally invasive percutaneous anterior occipitocervical fixation approach avoids this difficult exposure procedure. PURPOSE: This article describes a novel technique of percutaneous anterior occiput-to-axis screw fixation and its clinical outcomes. STUDY DESIGN: Technique report. METHODS: Anteroposterior, lateral and open-mouth views, and computed tomography scans are preoperatively obtained to appraise the feasibility of surgery. We extend our experience of using percutaneous anterior transarticular screw fixation to occiput-to-axis screw fixation. This procedure was performed on six patients. RESULTS: The operation was successfully performed on all patients without technical difficulties, and no vertebral artery, nerve injury or soft tissue (such as esophageal) complications occurred. All six patients followed up 10 to 39 months (averaged 20.5 months). Bone union was achieved in five patients, and the one patient lacking bone union was stable at final follow-up. The syringomyelia of four patients is almost complete reduction. No screw loosening or breakage has occurred. CONCLUSIONS: With the correct puncture point, angle of insertion, and use of the appropriate tools, we suggest that percutaneous anterior occiput-to-axis fixation technique is a feasible, safe, and minimally invasive procedure.

Vértebra Cervical Áxis/cirurgia , Osso Occipital/cirurgia , Fusão Vertebral/métodos , Siringomielia/cirurgia , Adulto , Parafusos Ósseos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fusão Vertebral/instrumentação , Resultado do Tratamento
Spine J ; 12(8): 656-62, 2012 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-22728075


BACKGROUND CONTEXT: As a minimally invasive spine surgery, percutaneous atlantoaxial fixation techniques using anterior transarticular screw (ATS) and posterior transarticular screw (PTS) have promising clinical results. However, transarticular screw fixation is technically demanding and carries a potential risk of iatrogenic vertebral artery (VA) injury. There were no available data comparing the anatomic risk of VA injury associated with these screws. PURPOSE: To evaluate the trajectories of percutaneous atlantoaxial ATS and PTS through three-dimensional (3D) computerized tomography. STUDY DESIGN: To compare the anatomic risk of VA injury between percutaneous ATS and PTS. PATIENT SAMPLE: Sixty patients ranged in age from 19 to 75 years (mean, 45.08 years) and included 35 men and 25 women. OUTCOME MEASURES: Image measurement of C2 isthmus height and C2 isthmus width and the distance between the medial-most superior articular facet to the medial-most edge of the VA groove of the C2 (D). METHODS: Sixty consecutive patients (in total) with lower cervical lesions were evaluated through 3D images reconstructed by a rapid 3D system. The maximum possible diameters of the percutaneous atlantoaxial ATS and PTS trajectories were compared and examined. Mean, range, and standard deviations for each type of screw, for left and right trajectories, and for men and women were calculated from 120 percutaneous atlantoaxial ATS and PTS measurements through SPSS. RESULTS: The maximum mean diameter differed significantly between the trajectories of 120 percutaneous atlantoaxial ATS and PTS. For screw trajectories ≤3.5 mm in diameter, 19.2% of the PTS trajectories were judged as risky, whereas all the anterior ones were judged as safe. CONCLUSIONS: From an anatomic perspective, percutaneous ATS fixation poses less anatomic risk of VA injury than percutaneous PTS fixation. As an alternative surgical therapy for atlantoaxial subluxation, percutaneous ATS fixation may play a more important role in the future.

Articulação Atlantoaxial/cirurgia , Parafusos Ósseos/efeitos adversos , Fusão Vertebral/instrumentação , Artéria Vertebral/diagnóstico por imagem , Adulto , Idoso , Articulação Atlantoaxial/diagnóstico por imagem , Feminino , Humanos , Imageamento Tridimensional , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos , Tomografia Computadorizada por Raios X , Lesões do Sistema Vascular/etiologia , Artéria Vertebral/anatomia & histologia , Artéria Vertebral/lesões