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Pediatr Dermatol ; 37(5): 943-944, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32981166
Cutis ; 105(4): E33-E34, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32463861
Australas J Dermatol ; 60(2): e119-e126, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30450536


BACKGROUND/OBJECTIVES: Lichen planus-like keratoses (LPLK) are benign skin lesions that can mimic malignancy; the clinical and dermoscopic features distinguishing lichen planus-like keratoses from skin tumors have not been extensively studied. The objective of this study was to identify dermoscopic features that may prevent unnecessary biopsies of lichen planus-like keratoses. METHODS: Retrospective, single-center, observational study of biopsied skin lesions at a tertiary center. We compared 355 lichen planus-like keratoses to 118 non-lichen planus-like keratoses lesions with lichen planus-like keratosis in the differential diagnosis biopsied from August 1, 2015, to December 31, 2016. The investigators were blinded to the diagnosis of the lesions. RESULTS: Lichen planus-like keratoses were most frequently non-pigmented (61.7%), truncal (52.1%), and on sun-damaged skin (69.6%); the majority occurred in Whites (95.5%) and females (62.8%). Dermoscopically, lichen planus-like keratoses were more likely than non-lichen planus-like keratoses to have scale (42.5% vs 31.4%, P = 0.03) and orange colour (8.2% vs 0.9%, P = 0.01). Among lesions with peppering (n = 76; 63 lichen planus-like keratoses and 13 non-lichen planus-like keratoses), coarse ± fine peppering (73% vs 38.5%, P = 0.02) and peppering as the only feature (34.9% vs 0%, P = 0.01) were associated with lichen planus-like keratoses. CONCLUSIONS: Lichen planus-like keratoses can be challenging to distinguish from benign and malignant skin tumors. The presence of dermoscopic scale and orange colour may aid in the recognition of lichen planus-like keratosis. Coarse peppering and the presence of peppering as the only dermoscopic feature may further aid the identification of pigmented lichen planus-like keratoses.

Dermoscopia , Ceratose/patologia , Líquen Plano/patologia , Idoso , Biópsia , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Estudos Retrospectivos , Pele/patologia , Neoplasias Cutâneas/diagnóstico
Clin Case Rep ; 5(4): 429-430, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28396762


A 27-year old male with Hodgkin's lymphoma was treated with combined chemotherapy that included bleomycin. He presented with pruritic erythematous, edematous linear lesions and was diagnosed to have flagellate hyperpigmentation, a rare side effect of bleomycin chemotherapy.

Wien Med Wochenschr ; 167(3-4): 74-77, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-27832422


A 67-year-old woman presented with a firm plaque in the perineal region, 16 months after diagnosis of a high-grade basaloid squamous cell carcinoma of the vagina and treatment by external beam radiation therapy and vaginal cuff brachytherapy. The differential diagnosis included radiation-induced morphea, radiation dermatitis, or, possibly, radiation-induced lichen sclerosus. Biopsy findings, including special staining, confirmed the diagnosis of radiation-induced lichen sclerosus. To our knowledge, this is the first report of radiation-induced lichen sclerosus of the vulvar region.

Braquiterapia , Carcinoma Basoescamoso/radioterapia , Radiodermatite/diagnóstico , Neoplasias Vaginais/radioterapia , Líquen Escleroso Vulvar/diagnóstico , Idoso , Diagnóstico Diferencial , Feminino , Humanos , Radiodermatite/patologia , Neoplasias Vaginais/patologia , Vulva/patologia , Líquen Escleroso Vulvar/patologia
J Am Board Fam Med ; 29(3): 408-10, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27170799


Basal cell carcinomas represent one of the most common skin cancers and often present initially in the primary care setting. Subtle basal cell carcinomas may be difficult to detect, and early detection of these carcinomas remains important in limiting patient morbidity. In this article, we present a simple diagnostic maneuver, "basal cell blanche," to increase early detection of basal cell carcinomas.

Carcinoma Basocelular/diagnóstico , Detecção Precoce de Câncer/métodos , Exame Físico/métodos , Atenção Primária à Saúde/métodos , Neoplasias Cutâneas/diagnóstico , Dermoscopia , Humanos