Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 5 de 5
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Inorg Chem ; 57(5): 2584-2593, 2018 Mar 05.
Artigo em Inglês | MEDLINE | ID: mdl-29430915

RESUMO

The design and synthesis of metal-organic frameworks (MOFs) enclosed with multiple catalytic active sites is favorable for cooperative catalysis, but is is still challenging. Herein, we developed a sequential postsynthetic ionization and metalation strategy to prepare bifunctional multivariate Zr-MOFs incorporating zinc porphyrin and imidazolium functionalities. Using this facile strategy, tetratopic [5,10,15,20-tetrakis(4-carboxyphenyl)porphyrinato]zinc(II) (ZnTCPP) ligands were successfully installed into the cationic Zr-MOF to obtain ZnTCPP⊂(Br-)Etim-UiO-66. These MTV-MOFs, including TCPP⊂Im-UiO-66, TCPP⊂(Br-)Etim-UiO-66, and ZnTCPP⊂(Br-)Etim-UiO-66, were well characterized and used in CO2 capture and conversion into cyclic carbonate from allyl glycidyl ether and CO2 under cocatalyst-free and 1 bar CO2 pressure conditions. It was found that the structural features and CO2 affinity properties of these MTV-MOFs can be tuned by introducing imidazolium groups or doping zinc sites. Additionally, ZnTCPP⊂(Br-)Etim-UiO-66 exhibited enhanced catalytic activities compared to other MTV-MOFs herein for obtaining the 3-allyloxy-1,2-proplyene carbonate product, which was attributed to the cooperative effect of Zn2+ sites and Br- ions in this microporous ionic MTV-MOF. ZnTCPP⊂(Br-)Etim-UiO-66 can be recycled easily and used at least three times.

2.
Chem Commun (Camb) ; 54(4): 342-345, 2018 Jan 04.
Artigo em Inglês | MEDLINE | ID: mdl-29182177

RESUMO

A mesoporous cationic Cr-MOF, termed FJI-C10, containing imidazolium moieties, Lewis acidic Cr3+ sites and free halogens is constructed for the first time by a topology-guided one-pot synthesis. FJI-C10 exhibits excellent performances in CO2 adsorption (20.2 wt% at 273 K and 1 bar) and chemical fixation of CO2 into cyclic carbonates without the use of co-catalyst under atmospheric pressure.

3.
Chem Biol Drug Des ; 85(6): 743-55, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25346294

RESUMO

Twenty-one novel oxime ether strobilurins containing indole moiety, which employed an indole group to stabilize the E-styryl group in Enoxastrobin, were designed and synthesized. The biological assay indicated that most compounds exhibited potent fungicidal activities. The structure-activity relationship study demonstrated that the synthesized methyl 3-methoxypropenoate oxime ethers 7b-e exhibited remarkably high activities among all the synthesized oxime ether compounds 7. Moreover, the fungicidal activities of methyl α-(methoxyimino)benzeneacetate oxime ethers compounds 7f-i and N-methoxy-carbamic acid methyl esters compounds 7j-m showed significant differences compared to the corresponding products of ammonolysis.


Assuntos
Fungos/efeitos dos fármacos , Fungicidas Industriais/química , Indóis/química , Oximas/química , Éteres/síntese química , Éteres/química , Éteres/farmacologia , Ácidos Graxos Insaturados/síntese química , Ácidos Graxos Insaturados/química , Ácidos Graxos Insaturados/farmacologia , Fungicidas Industriais/síntese química , Fungicidas Industriais/farmacologia , Indóis/síntese química , Indóis/farmacologia , Metacrilatos/síntese química , Metacrilatos/química , Metacrilatos/farmacologia , Oximas/síntese química , Oximas/farmacologia , Estrobilurinas , Relação Estrutura-Atividade
4.
Pest Manag Sci ; 71(3): 404-14, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24777582

RESUMO

BACKGROUND: Strobilurins are one of the most important classes of agricultural fungicides. To discover new strobilurin analogues with broad spectrum and high activity, a series of novel oxime ether strobilurin derivatives containing substituted benzofurans in the side chain were synthesised and bioassayed. RESULTS: The synthesised compounds were characterised by (1) H NMR, (13) C NMR, MS and HRMS. Bioassays demonstrated that most target compounds possessed good or excellent fungicidal activities, especially against Erysiphe graminis and Pyricularia oryzae. Furthermore, methyl 3-methoxypropenoate oxime ethers exhibited remarkably higher activities against E. graminis, Colletotrichum lagenarium and Puccinia sorghi Schw. Notably, (E,E)-methyl 3-methoxy-2-{2-[({[5-fluoro-1-(benzofuran-2-yl)ethylidene]amino}oxy)methyl]phenyl}propenoate (BSF2) and (E,E)-methyl 3-methoxy-2-{2-[({[5-chloro-1-(benzofuran-2-yl)ethylidene]amino}oxy)methyl]phenyl}propenoate (BSF3) were identified as the most promising candidates for further study. CONCLUSION: The present work demonstrates that oxime ether strobilurin derivatives containing benzofurans can be used as possible lead compounds for developing novel fungicides.


Assuntos
Fungos/efeitos dos fármacos , Fungicidas Industriais/química , Fungicidas Industriais/síntese química , Ácidos Graxos Insaturados/síntese química , Ácidos Graxos Insaturados/química , Ácidos Graxos Insaturados/farmacologia , Fungicidas Industriais/farmacologia , Espectroscopia de Ressonância Magnética , Metacrilatos/síntese química , Metacrilatos/química , Metacrilatos/farmacologia , Oximas/síntese química , Oximas/química , Oximas/farmacologia , Relação Estrutura-Atividade
5.
Bioorg Med Chem Lett ; 24(9): 2173-6, 2014 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-24717155

RESUMO

Twenty-one novel benzothiophene-substituted oxime ether strobilurins, which employed a benzothiophene group to stabilise the E-styryl group in Enoxastrobin (an unsaturated oxime strobilurin fungicide developed by Shenyang Research Institute of Chemical Industry, China) were designed and synthesised. The biological assay indicated that most compounds exhibited good or excellent fungicidal activities, especially against Colletotrichum lagenarium and Puccinia sorghi Schw. In addition, methyl 3-methoxypropenoate oxime ethers and N-methoxy-carbamic acid methyl esters exhibited good in vivo fungicidal activities against Erysiphe graminis, Colletotrichum lagenarium and Puccinia sorghi Schw. under the tested concentrations. Notably, (E,E)-methyl 3-methoxy-2-(2-((((6-chloro-1-(1H-benzo[b]thien-2-yl)ethylidene)amino)oxy)methyl)phenyl)propenoate (5E) exhibited more potent in vivo fungicidal activities against nearly all of the tested fungi at a concentration of 0.39 mg/L compared to Enoxastrobin.


Assuntos
Fungos/efeitos dos fármacos , Fungicidas Industriais/química , Fungicidas Industriais/toxicidade , Tiofenos/química , Tiofenos/toxicidade , Ácidos Graxos Insaturados/síntese química , Ácidos Graxos Insaturados/química , Ácidos Graxos Insaturados/toxicidade , Fungicidas Industriais/síntese química , Metacrilatos/síntese química , Metacrilatos/química , Metacrilatos/toxicidade , Oximas/síntese química , Oximas/química , Oximas/toxicidade , Estrobilurinas , Tiofenos/síntese química
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA