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Macromol Biosci ; 16(1): 57-62, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26222768

RESUMO

Amphiphilic diblock copolymer containing randomly distributed positive and negative charged monomers are synthesized using RAFT polymerization technique to be used as anti-bioadhesion coatings for hydrophobic surfaces. Quaternized 2-(dimethylamino) ethyl methacrylate and potassium 3-sulfopropyl methacrylate (P[qDMAEMA-co-KSPMA]) are randomly polymerized to yield an anti-bioadhesion block which is, in one pot, copolymerized with styrene as an anchoring block. This copolymer has demonstrated high anti-bioadhesion properties to avoid the blood clotting in medical devices through a simple and facile approach to preparation of pseudozwitterionic copolymers.


Assuntos
Sangue , Polímeros/química , Adsorção , Materiais Revestidos Biocompatíveis , Humanos , Metacrilatos/química , Polimerização , Estireno/química
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