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1.
Medicine (Baltimore) ; 100(31): e26757, 2021 Aug 06.
Artigo em Inglês | MEDLINE | ID: mdl-34397819

RESUMO

ABSTRACT: The role of cognitive, social and biological factors in the etiology of chronic periodontitis has been reported.The aim of this study was to evaluate the salivary cortisol level and interleukin-1 B level in patients of Chronic periodontitis in smokers and stress and nonsmokers without stress.The design of study randomized, prospective, double-blinded, and prospective study.The total sample size was comprised of 600 subjects between the ages of 20 and 50 years. The sample size was divided into 300 males and 300 females. Out of 600 subjects, 200 subjects comprised of subjects with chronic periodontitis with positive depression level with a history of smoking (Group I), 200 subjects comprised of subjects with chronic periodontitis without depression and without smoking (Group II), and 200 subjects who were taken as the control group comprised of healthy subjects without chronic periodontitis, without depression level, and no smoking history (Group III). Salivary cortisol levels were determined by enzyme-linked immunosorbent assay (ELISA).The result showed that there was a positive correlation between morning and evening salivary cortisol level in all the groups with correlation coefficient. There was significant higher value of salivary cortisol in Group I patients when compared with Group II and Group III. However, when the comparison of salivary cortisol levels was done between the Group II and Control group, the result showed nonsignificant P value.It is suggested that stress is positively correlated with the salivary cortisol levels in smokers and nonsmokers.


Assuntos
Periodontite Crônica/sangue , Hidrocortisona/análise , Interleucina-1beta/análise , Adulto , Biomarcadores/análise , Biomarcadores/sangue , Periodontite Crônica/diagnóstico , Periodontite Crônica/epidemiologia , Feminino , Voluntários Saudáveis , Humanos , Hidrocortisona/sangue , Interleucina-1beta/sangue , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Saliva/enzimologia , Fumar/efeitos adversos , Fumar/epidemiologia , Fumar/psicologia , Estresse Psicológico/epidemiologia , Estresse Psicológico/psicologia
2.
Microb Cell Fact ; 19(1): 212, 2020 Nov 18.
Artigo em Inglês | MEDLINE | ID: mdl-33208159

RESUMO

In this study, the self-extracted constipation treatment of traditional Chinese medicine extracts was applied to constipated rats. To explore the mechanism and role of the Chinese medicine for the treatment of constipation, the 16S rRNA sequencing and qRT-PCR technology were used to analyze the intestinal flora. We found that the relative abundance of Firmicutes with constipation was significantly higher accounted for 86.7%, while the gut microbiota was significantly changed after taking a certain dose of Chinese medicine, greatly increased the relative abundance of Lactobacillus accounted for 23.1%, enhanced the symbiotic relationships of Lactobacillus with other intestinal flora. The total copies of intestinal bacteria in the constipated rats decreased after taking the traditional Chinese medicine. Finally, this study results provides a theoretical basis for the treatment and understand the mechanism and effect of traditional Chinese medicine on rate constipation.

3.
J Sci Food Agric ; 97(8): 2553-2560, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-27714820

RESUMO

BACKGROUND: Maize was grown on compound soils constituted from mixtures of soft rock and sand at different ratios, and water use efficiency (WUE), nitrogen use efficiency (NUE) and fertilizer nitrogen use efficiency (FNUE) were quantified. The data were used to assist in designing strategies for optimizing water and nitrogen management practices for maize on the substrates used. Maize was sown in composite soil prepared at three ratios of soft rock and sand (1:1, 1:2 and 1:5 v/v) in Mu Us Sandy Land, Yuyang district, Yulin city, China. Yields, amount of drainage, nitrogen (N) leaching, WUE and NUE were calculated. Then a water and nitrogen management model (WNMM) was calibrated and validated. RESULTS: No significant difference in evapotranspiration of maize was found among compound soils with soft rock/sand ratios of 1:1, 1:2 and 1:5, while water drainage increased significantly with increasing soft rock/sand ratio. WUE increased to 1.30 kg m-3 in compound soil with 1:2 soft rock/sand ratio. Nitrogen leaching and ammonia volatilization were the main reason for nitrogen loss, and N reduction mainly relied on crop uptake. NUE and FNUE could reach 33.1 and 24.9 kg kg-1 N respectively. Water drainage and nitrogen leaching occurred mostly during heavy rainfall or irrigation. Through a scenario analysis of different rainfall types, water and fertilizer management systems were formulated each year. CONCLUSION: This study shows that soft rock plays a key role in improving the WUE, NUE and FNUE of maize. © 2016 Society of Chemical Industry.


Assuntos
Nitrogênio/metabolismo , Solo/química , Água/metabolismo , Zea mays/crescimento & desenvolvimento , Zea mays/metabolismo , Agricultura , China , Fertilizantes/análise , Nitrogênio/análise , Água/análise , Zea mays/química
4.
Neuropathology ; 36(5): 485-489, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-26947586

RESUMO

Mutations in the gene encoding caveolin-3 (CAV3) can cause a broad spectrum of clinical phenotypes, including limb girdle muscular dystrophy, rippling muscle disease, distal myopathy (MD), idiopathic persistent elevation of serum creatine kinase and cardiomyopathy. MD is a relatively rare subtype of caveolinopathy. Here, we report a sporadic case of a middle-aged female Chinese patient with MD in which a CAV3 mutation was identical to that previously reported in cases of rippling muscle disease. T1-weighted enhanced skeletal muscle MRI of the lower limbs showed an abnormal signal in the distal and proximal muscles. A muscle biopsy revealed moderate dystrophic changes, and immunohistochemical staining showed reduced CAV-3 expression in the plasmalemma. Genetic analysis revealed a heterozygous c.136G > A (p.Ala46Thr) CAV3 mutation that appeared to be de novo because it was absent from the patient's parents. This study suggested that the CAV3 c.136G > A (p.Ala46Thr) mutation can cause MD as well as different phenotypes in different individuals, suggesting that additional unknown loci must affect the disease phenotypes.


Assuntos
Caveolina 3/genética , Miopatias Distais/genética , Miopatias Distais/patologia , Adulto , Grupo com Ancestrais do Continente Asiático , Miopatias Distais/diagnóstico por imagem , Feminino , Heterozigoto , Humanos , Extremidade Inferior/diagnóstico por imagem , Extremidade Inferior/patologia , Músculo Esquelético/diagnóstico por imagem , Músculo Esquelético/patologia , Mutação , Linhagem , Fenótipo
5.
Bioresour Technol ; 165: 145-51, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24565875

RESUMO

Comparison of the bioremoval and recovery of Cd(II) by growing and grown marine bacterium Pseudoalteromonas sp. SCSE709-6 was performed in batch systems. Bioremoval with growing cells (Sorption I) showed better performance at low Cd(II) concentrations, whereas bioremoval with grown cells (Sorption II) had significant advantages in both removal efficiency and time consumption at high Cd(II) concentrations. The optimal pH was higher for Sorption I than for Sorption II for achieving the maximum Cd(II) removal efficiency. Complete desorption was achieved using either Na2EDTA or HNO3 as eluent. Cd(II) adsorbed on grown cells had higher tendency to be desorbed. Na2EDTA was a preferable eluent for the recycling biomaterials, whereas HNO3 performed better for the final security disposal of sludge. For Sorption II, both Langmuir and Freundlich isotherms well explained the biosorption behavior, and the pseudo-second-order model better expressed biosorption and desorption kinetics.


Assuntos
Cádmio/isolamento & purificação , Pseudoalteromonas/crescimento & desenvolvimento , Pseudoalteromonas/metabolismo , Adsorção , Biodegradação Ambiental , Difusão , Cinética , Modelos Teóricos , Espectrometria por Raios X , Espectroscopia de Infravermelho com Transformada de Fourier , Temperatura , Fatores de Tempo
6.
Extremophiles ; 17(5): 723-31, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23812889

RESUMO

Effective bio-removal of heavy metals is important for water treatment. Although a number of microorganism species demonstrated the ability of living cells to remove cadmium, most of them were tested at fixed concentration of metals, salinity, and temperature. This paper reported a research on the screening and performance of a newly developed deep-sea bacterium, Pseudoalteromonas sp. SCSE709-6, for Cd(II) removal by growing cells under a range of experimental conditions: 0-50 mg/L of Cd(II), 15-30 °C of incubation temperatures, 6.5-8.0 of initial pH, and 1.5-5.0 % of salinity. Study results revealed that Pseudoalteromonas sp. SCSE709-6 could remove more than 96 % of Cd(II) on growth. The Cd(II) bioremoval was in correlation but not in accordance with biomass. As cadmium concentrations increased, the Cd(II) removal by cell adsorption played an increasingly important role compared with that of intracellular accumulation. For the removal mechanism, Fourier transform infrared spectroscopy revealed that carboxyl, amido and hydroxyl of saccharides, and proteins in the extracellular polymeric substances are the most active groups for Cd(II) absorption. The bacterium reported in this study offers a new microbe strain for Cd(II) bioremediation.


Assuntos
Cádmio/metabolismo , Recuperação e Remediação Ambiental , Pseudoalteromonas/metabolismo , Pseudoalteromonas/isolamento & purificação , Água do Mar/microbiologia
7.
Guang Pu Xue Yu Guang Pu Fen Xi ; 33(11): 3041-3, 2013 Nov.
Artigo em Chinês | MEDLINE | ID: mdl-24555377

RESUMO

In order to explore the effect of extracelluar polymeric substances (EPS) on resistance and removal of heavy metals, the production of EPS, secreted by cadmium-resistant strain (SCSE425-7) and cadmium-removal strain (SCSE709-6) was investigated combined with Fourier transform infrared spectroscopy (FTIR). The results showed that the high resistance to cadmium of strain SCSE425-7 was related to the high production of soluble EPS, whereas SCSE709-6 secreted more insoluble EPS resulting in better cadmium removal performance. It was indicated that soluble extracellular carbohydrates may help the bacteria to enhance resistance to Cd2+, and insoluble EPS could contribute to Cd2+ removal effectively. The FTIR spectra showed that the peaks of amide and carboxyl were main functional groups for Cd2+ adsorption.


Assuntos
Bactérias/química , Carboidratos/química , Polímeros/química , Espectroscopia de Infravermelho com Transformada de Fourier , Adsorção , Biodegradação Ambiental , Cádmio , Metais Pesados
8.
Ying Yong Sheng Tai Xue Bao ; 21(5): 1081-9, 2010 May.
Artigo em Chinês | MEDLINE | ID: mdl-20707085

RESUMO

Based on the remote sensing data of Landsat TM (1985, 1995, and 2000) and CBERS (2006), and by using landscape pattern method and index model of regional land use change in combining with eco-function regionalization, this paper analyzed the dynamic characteristics of forest landscape in Chengdu City in 1985-2006. In the study period, over 17,000 hm2 of forest land lost, and the number and area of small- and medium-size patches changed significantly, indicating the apparent conversion and fragmentation of forest land. Forest land was mainly distributed in mountainous area, accounting for 70% of the total. In contrast, more number of patches was found in plain region, amounting to 70% of the total. The most rapid change of forest land area occurred in 1985-1995, especially in mountainous region. The relative change rate of forest land area in different eco-function regions also varied in different periods. Forest land, converted to or converted from, was mainly related to cropland and grassland. In 2000-2006, forest land was quite stable. Survival-oriented economic welfare, environmental security, and fast urbanization process were the main driving forces of the temporal dynamic change of forest landscape, whereas geographical division and socio-economic layout were the main constraints to the spatial dynamic change of forest landscape.


Assuntos
Ecossistema , Meio Ambiente , Árvores/crescimento & desenvolvimento , China , Produtos Agrícolas/crescimento & desenvolvimento , Poaceae/crescimento & desenvolvimento , Comunicações Via Satélite , Urbanização
9.
Chin Med J (Engl) ; 116(12): 1845-9, 2003 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-14687471

RESUMO

OBJECTIVE: To investigate the etiology, pathology, and mechanism of pathogenesis of Moyamoya disease. METHODS: A total of 15 human autopsies were analyzed. In addition, in order to create an animal model of the disease, 21 Japanese rabbits were divided randomly into two groups and subjected to injections of horse serum either intravenously or locally in the area of the sympathetic ganglia. Pathological and immunohistochemical characteristics were observed. RESULTS: The pathological features of the autopsies and the animal models both involved intima hyperplasia and stenosis or even occlusion of the lumen in the terminal ends of the internal carotid artery and the anterior and middle cerebral arteries. Disconnections or even breakages of the inner layer of the lumen were also observed, without an obvious inflammatory response. Hyperplasic smooth muscle cells of the medial membrane had extended inward through broken portions of the internal elastic lamina, with intima cell hyperplasia resulting in lumen stenosis. The hyperplastic vascular walls were positive for IgG and IgM. CONCLUSIONS: The etiology of Moyamoya disease may involve allergic angiitis. A possible mechanism is that proximal portions of the circle of Willis first develop chronic stenosis or occlusion, leading to compensatory small vessel proliferation, which perforates into the cerebral parenchyma.


Assuntos
Doença de Moyamoya/patologia , Adolescente , Adulto , Animais , Artéria Carótida Interna/patologia , Criança , Humanos , Hiperplasia , Masculino , Pessoa de Meia-Idade , Artéria Cerebral Média/patologia , Doença de Moyamoya/etiologia , Coelhos , Túnica Íntima/patologia
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