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1.
ACS Appl Mater Interfaces ; 12(3): 4150-4154, 2020 Jan 22.
Artigo em Inglês | MEDLINE | ID: mdl-31885250

RESUMO

The emerging surface/edge electronic phases driven by broken symmetry effects have attracted great attention in low-dimensional electronic systems. However, experimental proof on their existence in ferroelectric oxides at the atomic scale is still missing. In this work, metallic surface states are observed on layered Bi2WO6 by scanning tunneling microscopy/spectroscopy. Differential conductance is remarkably enhanced near the step edge compared with that on the terrace, forming a one-dimensional edge state. Density functional theory calculations verify that symmetry breaking at the surface determines the electronic structures and O 2p orbitals contribute the most to the density of states around the Fermi level. Our discovery provides a new strategy toward the hidden phases on other correlated oxide surfaces.

2.
Scand J Gastroenterol ; 54(11): 1397-1402, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31656114

RESUMO

Purpose: To compare different percutaneous approaches to manage occluded primary uncovered self-expandable metal stents (SEMS) in patients with unresectable malignant hilar biliary obstruction (MHBO).Materials and Methods: A retrospective study was performed in patients with MHBO who underwent percutaneous management of occluded primary uncovered SEMS between January 2014 and January 2018. Patients were assigned into three groups based on the types of secondary stents, which included SEMS, internal-external drainage (IED), and external drainage (ED). Clinical success, requirement for reintervention, survival times, complications, and cost were evaluated.Results: A total of 58 patients were identified, with 21, 9, and 28 patients received SEMS, IED, and ED treatments, respectively. The overall clinical success rate was 67.2% (39/58), with no significant difference among three groups (p = .489). The median time to reintervention was 82, 57, and 61 days for the SEMS, IED, and ED groups, respectively (p = .045 for SEMS vs. IED; p = .011 for SEMS vs. ED). There was no significant difference in the median survival times among three groups (p = .308). Seven patients (12.7%) experienced minor complications including self-limiting haemobilia (n = 3) and catheter-related pain (n = 4). Fourteen patients (24.1%) had major complications, including early cholangitis (n = 8), pancreatitis (n = 3), stent dislodgement (n = 2), and bile leakage (n = 1). There was no statistical difference in the mean cost of the management of occluded primary SEMS between the three groups (p = .162).Conclusion: Uncovered SEMS could provide a longer duration to reintervention compared to the catheter drainages to manage occluded primary SEMS in patients with unresectable MHBO.

3.
Nanoscale ; 11(43): 20868-20875, 2019 Nov 21.
Artigo em Inglês | MEDLINE | ID: mdl-31657407

RESUMO

We demonstrate a tunable longwave infrared photodetector with ultra-high sensitivity based on graphene surface plasmon polaritons controlled by ferroelectric domains. The simulated results show that the photodetector shows a tunable absorption peak, modulated by periodically polarized ferroelectric domains at the nanoscale, with an ultra-high responsivity up to 7.62 × 106 A W-1 and a detectivity of ∼6.24 × 1013 Jones (Jones = cm Hz1/2 W-1) in the wavelengths ranging from 5 to 20 µm at room temperature. The potential mechanism for the prominent performances of the proposed photodetector can be attributed to the highly confined graphene surface plasmons excited by the local electrical field across the interface of the graphene and ferroelectric layer resonant to the incident wavelength, which could be easily controlled by the features of the ferroelectric domains. Compared with the silicon-based graphene plasmonic photodetector using a complex process of micro-nano fabrication, the proposed photodetector provides the advantages of a more convenient and controllable technique without the need for patterning graphene, and lower energy consumption due to the non-volatile properties of the ferroelectrics without an additional contact electrode. The tunable spectral response and the ultra-high responsivity make the graphene plasmonic photodetector tuned by the ferroelectric domains promising in practical applications of micro-spectrometers and other light sensing devices.

4.
Nanoscale ; 11(43): 20514-20521, 2019 Nov 21.
Artigo em Inglês | MEDLINE | ID: mdl-31660549

RESUMO

Ferroelectric topological configurations confined in nanostructures have attracted intensive interest both in fundamental physics and potential applications in non-volatile nanoelectronic devices. However, the preparation approaches such as chemical synthesis and template or electron beam etching inevitably induce damage and contamination; also, these are complicated processes. Herein, by a delicate design of the wetting layer and growth temperature, self-assembled ferroelectric nanoislands were achieved with the BiFeO3/(La,Sr)MnO3/LaAlO3 heterostructure. Based on the thermodynamic analysis, the much lower surface energy (∼0.47 J m-2) of the (La,Sr)MnO3 (∼2-12 nm)/LaAlO3 system than that (∼1.0 J m-2) of BiFeO3 provides the probability for the transformation of layered morphology into nanoislands. From the dynamic perspective, the high growth temperature (∼650-680 °C) helps to step over the energy barrier (∼50 meV per atom) by stimulating the formation of periodically arrayed dislocations at the BiFeO3/(La,Sr)MnO3 interface, which on the one hand releases the epitaxial elastic energy and on the other hand evokes the nucleation of the R-phase nanoisland array. More excitingly, this approach with a wonderful new growth mechanism can also be employed in other ferroelectric model systems such as BaTiO3, which provides a new strategy for the design of novel nanoelectronic devices based on ferroelectric perovskite nanostructures.

5.
ACS Appl Mater Interfaces ; 11(40): 37279-37284, 2019 Oct 09.
Artigo em Inglês | MEDLINE | ID: mdl-31529959

RESUMO

Real-space access of the orbital degree of freedom in complex oxides is still challenging due to intricate electronic hybridization. Here, we report a direct observation of reproducible orbital-selective tunneling on a novel SrTiO3(001) surface by scanning tunneling microscopy. The electronic structures reversibly switch between two different sets of symmetries depending on the sample bias, which is accompanied by a remarkable change in energy-dependent spectroscopy data. Tunneling spectrum combined with density functional theory calculations elucidates that symmetry-breaking at the surface determines the crystal-splitting field of eg/t2g orbitals with a strong in-plane anisotropy so that electrons alternatingly fill eg and t2g orbitals during the imaging process with different biases. This surface superstructure provides a new strategy toward understanding orbital textures and orbital selectivity in complex oxides.

6.
Turk J Gastroenterol ; 30(8): 714-721, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31418416

RESUMO

BACKGROUND/AIMS: For distal malignant biliary obstruction (MBO), a percutaneous metal stent is usually inserted by the transpapillary method. However, stent-related complications and recurrent biliary obstruction following transpapillary stent placement are concerns, and survival analysis of patients with distal MBO has rarely been done. MATERIALS AND METHODS: From January 2012 to March 2016, 104 patients underwent transpapillary uncovered metal stent placement for distal MBO at our institution. Clinical success, complications, recurrent biliary obstruction rates, and predictors of survival were analyzed. RESULTS: Of the total 104 patients, clinical success after stent insertion was achieved in 93 patients (90.3%). Major complications were observed in 24 patients (23.1%), which were as follows: cholangitis in 19 patients; pancreatitis in four patients; and biloma in one patient. Recurrent biliary occlusion was observed in 28 patients (26.9%). The median overall survival period was 162 days. The 3-, 6-, and 12-month overall survival rates after stent insertion were 64.4%, 41.3%, and 10.6%, respectively. Results of multivariate analysis indicated that metastatic carcinoma compared with ampullary carcinoma (HR=3.82; 95% CI, 1.30-11.24; p=0.015) and longer biliary stricture (HR=1.04; 95% CI, 1.02-1.06; p<0.001) were independent risk factors for worse survival after metal stent insertion. CONCLUSION: Transpapillary stent placement was found to be effective with acceptable complication rates for treating distal MBO. Primary tumor and length of biliary stricture were found to be statistically significant independent prognostic factors for survival.

7.
ACS Appl Mater Interfaces ; 11(28): 25569-25577, 2019 Jul 17.
Artigo em Inglês | MEDLINE | ID: mdl-31264829

RESUMO

Electric-field control of magnetism (EFCM) is very important for the exploration of high-density, fast, and nonvolatile random-access memory with ultralow energy consumption. Here, we report the electric-field-induced ferroelectric phase transitions in Pb(Mg1/3Nb2/3)0.82Ti0.18O3 (PMN-0.18PT) and symmetry breaking of EFCM behaviors for corresponding directions in multiferroic heterostructures composed of amorphous ferromagnetic Co40Fe40B20 (CoFeB) and PMN-0.18PT. We uncover a new mechanism behind the unusual phenomena, involving coupling between CoFeB and PMN-0.18PT via complex cooperation of electric-field-induced ferroelectric phase transitions, competition of different ferroelectric domains, and internal electric field in PMN-0.18PT. The deterministic EFCM with reversible and nonvolatile nature opens up a new avenue for exploring EFCM in multiferroic heterostructures and is also significant for applications.

8.
Nat Nanotechnol ; 14(7): 691-697, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31011219

RESUMO

Spin waves may constitute key components of low-power spintronic devices. Antiferromagnetic-type spin waves are innately high-speed, stable and dual-polarized. So far, it has remained challenging to excite and manipulate antiferromagnetic-type propagating spin waves. Here, we investigate spin waves in periodic 100-nm-wide stripe domains with alternating upward and downward magnetization in La0.67Sr0.33MnO3 thin films. In addition to ordinary low-frequency modes, a high-frequency mode around 10 GHz is observed and propagates along the stripe domains with a spin-wave dispersion different from the low-frequency mode. Based on a theoretical model that considers two oppositely oriented coupled domains, this high-frequency mode is accounted for as an effective antiferromagnetic spin-wave mode. The spin waves exhibit group velocities of 2.6 km s-1 and propagate even at zero magnetic bias field. An electric current pulse with a density of only 105 A cm-2 can controllably modify the orientation of the stripe domains, which opens up perspectives for reconfigurable magnonic devices.

9.
ACS Appl Mater Interfaces ; 11(9): 9548-9556, 2019 Mar 06.
Artigo em Inglês | MEDLINE | ID: mdl-30724082

RESUMO

Single-phase (00 l)-oriented Bi2Te3 topological insulator thin films have been deposited on (111)-oriented ferroelectric 0.71Pb(Mg1/3Nb2/3)O3-0.29PbTiO3 (PMN-PT) single-crystal substrates. Taking advantage of the nonvolatile polarization charges induced by the polarization direction switching of PMN-PT substrates at room temperature, the carrier density, Fermi level, magnetoconductance, conductance channel, phase coherence length, and quantum corrections to the conductance can be in situ modulated in a reversible and nonvolatile manner. Specifically, upon the polarization switching from the positively poled Pr+ state (i.e., polarization direction points to the film) to the negatively poled Pr- (i.e., polarization direction points to the bottom electrode) state, both the electron carrier density and the Fermi wave vector decrease significantly, reflecting a shift of the Fermi level toward the Dirac point. The polarization switching from Pr+ to Pr- also results in significant increase of the conductance channel α from -0.15 to -0.3 and a decrease of the phase coherence length from 200 to 80 nm at T = 2 K as well as a reduction of the electron-electron interaction. All these results demonstrate that electric-voltage control of physical properties using PMN-PT as both substrates and gating materials provides a simple and a straightforward approach to realize reversible and nonvolatile tuning of electronic properties of topological thin films and may be further extended to study carrier density-related quantum transport properties of other quantum matter.

10.
ACS Appl Mater Interfaces ; 11(7): 7296-7302, 2019 Feb 20.
Artigo em Inglês | MEDLINE | ID: mdl-30675776

RESUMO

Layered perovskites with Aurivillius phase have drawn tremendous attention recently, owing to their high ferroelectric Curie temperatures, large spontaneous polarization, and fatigue-free and environment-friendly characteristics. Bi2WO6 is one of the simplest members in the Aurivillius family with superior ferroelastic and photo-electrochemical behaviors. The self-assembly fabrication of its nanoarchitectures and strategic modulation of their ferroelastic switching are crucial toward highly efficient nanoscale applications. In this work, Bi2WO6 nanobrick arrays were epitaxially grown along the orthorhombic direction in a self-assembled way. Such a nanoscale topology supports out-of-plane and in-plane vectors of ferroelectric polarizations, enabling a perpendicular voltage manipulation of these emerging ferroelectric/elastic domains. Combining the scanning probe technique and transmission electron microscopy, we confirmed the in-plane polarization vectors of 78.6 and 101.4° within the crystallographic axes of the nanobricks with respect to the (110) plane of the substrate. Thus, this work provides new opportunities for ferroelectric/elastic engineering in Bi2WO6 nanostructures for a wide range of applications, such as sensing, actuating, and catalysis.

11.
Cardiovasc Intervent Radiol ; 42(2): 276-282, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30411153

RESUMO

OBJECTIVE: To evaluate predictive factors of recurrent biliary obstruction (RBO) following percutaneous uncovered metal stent placement for unresectable distal malignant biliary obstruction (MBO) by using a competing risk model. MATERIALS AND METHODS: Between March 2012 and March 2016, 119 patients underwent percutaneous uncovered metal stent placement with distal MBO at our institution. Univariate and multivariate analyses were conducted to identify the prognostic factors for RBO using a competing risk model. RESULTS: The median overall survival period was 170 days (range 19-775 days). Recurrent biliary obstruction before death was observed in 34 patients (28.6%). The 3-, 6-, and 12-month cumulative incidences of RBO were 14.3%, 21.0%, and 27.7%, respectively. A multivariate analysis indicated that ampullary carcinoma compared with metastatic carcinoma (hazard ratio [HR] = 4.86; 95% confidence interval [CI], 1.74-13.54; P = 0.003) and a stent insertion above the sphincter of Oddi (HR 2.49; 95% CI, 1.11-5.62; P = 0.028) were the independent risk factors for RBO when we considered death to be a competing risk. CONCLUSION: Ampullary carcinoma and stent insertion above the sphincter of Oddi were risk factors for RBO in these patients who received percutaneous transhepatic stent placement.


Assuntos
Neoplasias do Sistema Biliar/complicações , Colestase/etiologia , Colestase/terapia , Stents , Idoso , Feminino , Humanos , Masculino , Metais , Modelos de Riscos Proporcionais , Recidiva , Estudos Retrospectivos , Fatores de Risco , Análise de Sobrevida
13.
Nat Commun ; 9(1): 3809, 2018 09 18.
Artigo em Inglês | MEDLINE | ID: mdl-30228308

RESUMO

Ferroelectrics, which generate a switchable electric field across the solid-liquid interface, may provide a platform to control chemical reactions (physical properties) using physical fields (chemical stimuli). However, it is challenging to in-situ control such polarization-induced interfacial chemical structure and electric field. Here, we report that construction of chemical bonds at the surface of ferroelectric BiFeO3 in aqueous solution leads to a reversible bulk polarization switching. Combining piezoresponse (electrostatic) force microscopy, X-ray photoelectron spectroscopy, scanning transmission electron microscopy, first-principles calculations and phase-field simulations, we discover that the reversible polarization switching is ascribed to the sufficient formation of polarization-selective chemical bonds at its surface, which decreases the interfacial chemical energy. Therefore, the bulk electrostatic energy can be effectively tuned by H+/OH- concentration. This water-induced ferroelectric switching allows us to construct large-scale type-printing of polarization using green energy and opens up new opportunities for sensing, high-efficient catalysis, and data storage.

14.
Nat Nanotechnol ; 13(10): 972, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30065308

RESUMO

In the version of this Article originally published, the corresponding author names in the author list appeared in the reverse order; they should have read 'Jinxing Zhang and Ce-Wan Nan'. The order of these authors' initials in the 'Correspondence and requests for materials' statement were similarly affected. These errors have now been corrected in all versions of the Article.

15.
ACS Appl Mater Interfaces ; 10(38): 32809-32817, 2018 Sep 26.
Artigo em Inglês | MEDLINE | ID: mdl-30156403

RESUMO

We report the fabrication of 0.71Pb(Mg1/3Nb2/3)O3-0.29PbTiO3 (PMN-0.29PT)-based ferroelectric field effect transistors (FeFETs) by the epitaxial growth of cobalt-doped tin dioxide (SnO2) semiconductor thin films on PMN-0.29PT single crystals. Using such FeFETs we realized in situ, reversible, and nonvolatile manipulation of the electron carrier density and achieved a large nonvolatile modulation of the resistance (∼330%) of the SnO2:Co films through the polarization switching of PMN-0.29PT at 300 K. Particularly, combining the ferroelectric gating with piezoresponse force microscopy, X-ray diffraction, Hall effect, and magnetoresistance (MR), we rigorously disclose that both sign and magnitude of the MR are intrinsically determined by the electron carrier density, which could modify the s-d exchange interaction of the SnO2:Co films. Furthermore, we realized multilevel resistance states of the SnO2:Co films by combining the ferroelectric gating with ultraviolet light illumination, demonstrating that the FeFETs have potential applications in multistate resistive memories and electro-optical devices.

16.
Nat Nanotechnol ; 13(10): 947-952, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-30038370

RESUMO

Charged domain walls in ferroelectrics exhibit a quasi-two-dimensional conduction path coupled to the surrounding polarization. They have been proposed for use as non-volatile memory with non-destructive operation and ultralow energy consumption. Yet the evolution of domain walls during polarization switching makes it challenging to control their location and conductance precisely, a prerequisite for controlled read-write schemes and for integration in scalable memory devices. Here, we explore and reversibly switch the polarization of square BiFeO3 nanoislands in a self-assembled array. Each island confines cross-shaped, charged domain walls in a centre-type domain. Electrostatic and geometric boundary conditions induce two stable domain configurations: centre-convergent and centre-divergent. We switch the polarization deterministically back and forth between these two states, which alters the domain wall conductance by three orders of magnitude, while the position of the domain wall remains static because of its confinement within the BiFeO3 islands.

17.
Neurocrit Care ; 29(3): 426-434, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-29946761

RESUMO

BACKGROUND: We performed a meta-analysis to evaluate the outcomes of acute ischemic stroke (AIS) in patients treated with mechanical thrombectomy (MT), according to diabetes mellitus and admission glucose level (AGL). METHODS: We systematically reviewed previous studies in PubMed that reported outcomes of MT in AIS patients and their relationships with diabetes mellitus or AGL. We used functional independence (modified Rankin score ≤ 2 at 3 months) as the primary end point. RESULTS: Data from 12,653 patients in 47 articles that evaluated the effect of diabetes mellitus or AGL on outcomes after MT were included. Compared with patients without a history of diabetes mellitus, patients with a diabetes mellitus history had significantly lower odds of functional independence in both the unadjusted meta-analysis (odds ratio [OR] 0.64; 95% confidence interval [CI] 0.54-0.75) and the multivariable analysis (OR 0.48; 95% CI 0.33-0.71). Similarly, higher AGL was associated with an unfavorable functional outcome in the unadjusted meta-analysis (pooled effect size - 0.38; 95% CI - 0.45 to - 0.31), and the adjusted OR (95% CI) per 1 mmol/L increase in AGL was 0.87 (0.83-0.92) for functional independence according to the combined multivariable results. Recanalization rate and symptomatic intracranial hemorrhage were neither related to AGL nor different in patients with or without diabetes mellitus. CONCLUSIONS: The present study confirms that a history of diabetes mellitus and high AGL are associated with unfavorable functional outcomes at 3 months after MT in AIS patients. However, the causal relationship between hyperglycemia and poor prognosis remains undetermined, and further investigations are required to ascertain whether AIS patients receiving MT could benefit from intensive glucose control.


Assuntos
Isquemia Encefálica , Comorbidade , Diabetes Mellitus , Hiperglicemia , Trombólise Mecânica , Acidente Vascular Cerebral , Isquemia Encefálica/epidemiologia , Isquemia Encefálica/terapia , Diabetes Mellitus/epidemiologia , Humanos , Hiperglicemia/epidemiologia , Trombólise Mecânica/estatística & dados numéricos , Acidente Vascular Cerebral/epidemiologia , Acidente Vascular Cerebral/terapia
18.
J Biol Chem ; 293(31): 12199-12208, 2018 08 03.
Artigo em Inglês | MEDLINE | ID: mdl-29914983

RESUMO

Acute pulmonary embolism (APE)-induced inflammation contributes to cardiomyocyte injury and dysfunction in the right ventricle (RV) of the heart. The interactions of cyclophilin A with its ligand extracellular matrix metalloproteinase inducer (EMMPRIN or CD147) may be involved in this inflammatory process. To this end, here we induced APE by intravenous injections of microspheres in Sprague-Dawley rats. We found that after the APE, cyclophilin A and CD147 levels increased synchronously in RV tissue following APE and peaked at 24 h. The cyclophilin A inhibitor cyclosporine A attenuated the APE-induced cyclophilin A levels, and a monoclonal antibody of CD147 (anti-CD147) abrogated the elevation of CD147 in the RV but not the increase of cyclophilin A. Importantly, treatment with cyclosporine A, anti-CD147, or both attenuated APE-induced increases in RV systolic pressure, plasma cardiac troponin-I (cTnI) concentrations, the RV/left ventricle diameter ratio, and the Tei index, measured by echocardiography 24 h after APE induction. These beneficial effects were associated with reduced RV neutrophil infiltration and prevention of matrix metalloproteinase 9 (MMP-9) and MMP-2 activation. These findings suggested that inhibiting the cyclophilin A-CD147 interaction attenuates APE-associated RV cardiomyocyte injury and dysfunction by suppressing inflammation. We further proposed that cyclophilin A and CD147 might participate in APE-induced pathological processes by partly activating the ERK1/2 kinase-nuclear factor-κB pathway. We conclude that the cyclophilin A-CD147 interaction may represent a potential therapeutic target for managing APE.


Assuntos
Basigina/metabolismo , Ciclofilina A/metabolismo , Ventrículos do Coração/lesões , Ventrículos do Coração/fisiopatologia , Embolia Pulmonar/metabolismo , Animais , Basigina/genética , Pressão Sanguínea , Ciclofilina A/genética , Ecocardiografia , Ventrículos do Coração/metabolismo , Humanos , Masculino , Metaloproteinase 9 da Matriz/metabolismo , Ligação Proteica , Embolia Pulmonar/genética , Embolia Pulmonar/fisiopatologia , Ratos , Ratos Sprague-Dawley , Troponina I/sangue
19.
ACS Appl Mater Interfaces ; 10(18): 16160-16168, 2018 May 09.
Artigo em Inglês | MEDLINE | ID: mdl-29687707

RESUMO

Transparent flexible electrodes are in ever-growing demand for modern stretchable optoelectronic devices, such as display technologies, solar cells, and smart windows. Such sandwich-film-electrodes deposited on polymer substrates are unattainable because of the low quality of the films, inducing a relatively large optical loss and resistivity as well as a difficulty in elucidating the interference behavior of light. In this article, we report a high-quality AZO/Au/AZO sandwich film with excellent optoelectronic performance, e.g., an average transmittance of about 81.7% (including the substrate contribution) over the visible range, a sheet resistance of 5 Ω/sq, and a figure-of-merit (FoM) factor of ∼55.1. These values are well ahead of those previously reported for sandwich-film-electrodes. Additionally, the interference behaviors of light modulated by the coat and metal layers have been explored with the employment of transmittance spectra and numerical simulations. In particular, a heater device based on an AZO/Au/AZO sandwich film exhibits high performance such as short response time (∼5 s) and uniform temperature field. This work provides a deep insight into the improvement of the film quality of the sandwich electrodes and the design of high-performance transparent flexible devices by the application of a flexible substrate with an atomically smooth surface.

20.
Saudi J Gastroenterol ; 24(2): 82-86, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29637914

RESUMO

Background/Aims: Metal stent insertion is a common palliative treatment for distal malignant biliary obstruction (MBO) but whether placement across the sphincter of Oddi (SO) causes more complications or shorter survival is in question. The aim of this study was to compare the clinical outcomes of percutaneous uncovered self-expandable metal stent placement above and across the SO in patients with distal MBO. Patients and Methods: We retrospectively studied 59 patients who underwent uncovered metal stent placement for distal MBO between January 2012 and March 2016. Stents were placed above the SO for 22 subjects (group A) and across the SO for 37 subjects (group B). Early cholangitis, stent occlusion, and overall survival time were compared between the two groups. Results: Clinical success was 90.9 and 86.5% for groups A and B, respectively. Early cholangitis occurred in 2 patients (9.1%) in group A and in 6 patients (16.2%) in group B (P = 0.645). Median stent patency and median survival time was 105 and 140 days for group A, 120 and 160 days for group B, respectively. The stent occlusion (31.8% in group A and 21.6% in group B, P = 0.454) and the cumulative stent patency times (P = 0.886) did not differ between the two groups. There was no significant difference in cumulative patient survival between the two groups (P = 0.810). Conclusion: Uncovered metal stent placement across the SO did not significantly affect early cholangitis, stent patency, or patient survival.


Assuntos
Neoplasias dos Ductos Biliares/cirurgia , Colestase/cirurgia , Stents Metálicos Autoexpansíveis/efeitos adversos , Esfíncter da Ampola Hepatopancreática/cirurgia , Idoso , Colangiopancreatografia Retrógrada Endoscópica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Análise de Sobrevida
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