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1.
PLoS Comput Biol ; 15(11): e1007484, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31747389

RESUMO

Visual neurons respond to static images with specific dynamics: neuronal responses sum sub-additively over time, reduce in amplitude with repeated or sustained stimuli (neuronal adaptation), and are slower at low stimulus contrast. Here, we propose a simple model that predicts these seemingly disparate response patterns observed in a diverse set of measurements-intracranial electrodes in patients, fMRI, and macaque single unit spiking. The model takes a time-varying contrast time course of a stimulus as input, and produces predicted neuronal dynamics as output. Model computation consists of linear filtering, expansive exponentiation, and a divisive gain control. The gain control signal relates to but is slower than the linear signal, and this delay is critical in giving rise to predictions matched to the observed dynamics. Our model is simpler than previously proposed related models, and fitting the model to intracranial EEG data uncovers two regularities across human visual field maps: estimated linear filters (temporal receptive fields) systematically differ across and within visual field maps, and later areas exhibit more rapid and substantial gain control. The model is further generalizable to account for dynamics of contrast-dependent spike rates in macaque V1, and amplitudes of fMRI BOLD in human V1.

2.
Artigo em Inglês | MEDLINE | ID: mdl-31294676

RESUMO

The purpose of this study was to investigate pesticide residues in bell peppers from Shandong Province, China. A total of 299 samples were collected from 17 cities in 2016. The concentrations of 26 pesticide residues were determined by gas chromatography with mass spectrometry (GC-MS). The results showed that there were 25 pesticides (15 OPs, 7 PYs, 3 CBs) found in 86 bell pepper samples, and the total number of positives was 120. The total frequency was 28.76%. The detection frequency for OPs, PYs and CBs was 16.39%, 12.37% and 3.01%, respectively. The most frequently detected pesticide was bifenthrin, with the frequency of 5.02%. 5.35% of samples contained pesticide residues above the maximum residue limits (MRLs) set by China. 7.36% of samples contained more than one pesticide. The values of %ADI were below 100, while the %ARfD of carbofuran and methidathion exceeded 100 for children. The cumulative risk was highest for OPs. From the public health point of view, the levels of pesticide residues in bell peppers do not pose a serious health risk to adults, but the acute health risk to children should be paid more attention.


Assuntos
Capsicum/química , Contaminação de Alimentos/análise , Resíduos de Praguicidas/análise , Piretrinas/análise , Adulto , Criança , China , Cromatografia Gasosa-Espectrometria de Massas , Humanos , Controle de Qualidade , Medição de Risco , Extração em Fase Sólida
3.
J Sci Food Agric ; 99(8): 4063-4071, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30761529

RESUMO

BACKGROUND: Edible packaging and coating with natural antimicrobials such as essential oils is an emerging technology for the control of pathogen growth in meat products. This study aimed to explore ethyl cellulose (EC) of three viscosities for the structuring of cinnamon essential oil (CEO), and investigated the physicochemical properties of the resulting oleogel and its emulsion, as well as the corresponding antibacterial activity in model and actual environments (as in sausages). RESULTS: The network structure of CEO-EC oleogel was more compact with increased EC viscosity, thereby improving the binding capacity and stability of the oil. A positive correlation was found between EC viscosity and particle size of the CEO-EC emulsion. The 45 cP CEO-EC emulsion exhibited greatest antimicrobial activitiy in models with Escherichia coli (E. coli) O157:H7 (ATCC 700927) and Staphylococcus aureus (S. aureus) (ATCC 29213), as well as in sausage, with respect to total counts of mesophilic bacteria, psychrotrophs, lactobacilli, and pseudomonads. CONCLUSION: The CEO-EC oleogel has antibacterial activity, determined by the EC viscosity, that provide potential antibacterial protection for meat products and might be especially suitable for some traditional Chinese ready-to-eat sausages without strictly sealed packaging. © 2019 Society of Chemical Industry.


Assuntos
Antibacterianos/química , Celulose/análogos & derivados , Cinnamomum zeylanicum/química , Óleos Voláteis/química , Óleos Voláteis/farmacologia , Óleos Vegetais/química , Antibacterianos/farmacologia , Celulose/química , Escherichia coli O157/efeitos dos fármacos , Escherichia coli O157/crescimento & desenvolvimento , Listeria monocytogenes/efeitos dos fármacos , Listeria monocytogenes/crescimento & desenvolvimento , Testes de Sensibilidade Microbiana , Compostos Orgânicos/química , Compostos Orgânicos/farmacologia , Óleos Vegetais/farmacologia , Staphylococcus aureus/efeitos dos fármacos , Staphylococcus aureus/crescimento & desenvolvimento , Viscosidade
4.
Mol Nutr Food Res ; 63(3): e1801029, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30408325

RESUMO

SCOPE: Cruciferous vegetable consumption is associated with favorable health outcomes. Bioactive compounds arising in these, especially isothiocyanates, exert effects that contribute to prevention of disease, in large part through the attenuation of inflammation and oxidative stress. However, much about isothiocyanate metabolites and their role as biomarkers of crucifer intake remain unknown. METHODS AND RESULTS: The utility and limitations of 2-thiothiazolidine-4-carboxylic acid (TTCA) as a urinary biomarker of broccoli beverage intake are tested in a randomized crossover clinical trial where 50 participants consumed either a glucoraphanin-rich (GRR) or sulforaphane-rich (SFR) beverage. Compared to run-in and wash-out periods, significantly higher urinary TTCA is observed after broccoli beverage consumption. Measurements also show that TTCA is present in beverage powders and in all tested cruciferous vegetables. GRR results in excretion of ≈87% of the ingested TTCA while SFR results in excretion of ≈176%. Elevated urinary TTCA is observed in rats administered 100 µmol kg-1 SFN. Unlike SFN, TTCA does not activate Nrf2-mediated cytoprotective signaling. CONCLUSION: Collectively, TTCA appears to be a common isothiocyanate-derived metabolite that has the capacity to be utilized as a biomarker of cruciferous vegetables that would be beneficial for objective and quantitative tracking of intake in studies.


Assuntos
Brassica , Isotiocianatos/metabolismo , Tiazolidinas/urina , Animais , Biomarcadores , Células Cultivadas , Estudos Cross-Over , Feminino , Humanos , Ratos , Verduras
5.
Food Addit Contam Part B Surveill ; 12(1): 10-17, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30035665

RESUMO

This study was designed to investigate the occurrence and exposure assessment of multiple mycotoxins in corn-based food products from Shandong Province, China. Results demonstrated that the mean level of total mycotoxins in test samples was 197.2 µg/kg. The most frequently found mycotoxins were deoxynivalenol (96.7%) and fumonisin B1 (94.4%), with mean contamination levels of 65.24 and 128.2, respectively. Among these corn-based food products, thin corn pancake had the highest mean contamination (886.7 µg/kg), followed by wotou (143.7 µg/kg), corn cake (135.4 µg/kg) and mantou (63.73 µg/kg). The average exposure values to total fumonisins and deoxynivalenol were 0.05 and 0.02 µg/kg bw/day, which were lower than the provisional maximum tolerable daily intake values of 2 and 1 µg/kg bw/day, respectively, as established by the Joint FAO/WHO Expert Committee on Food Additives. In the future strict control and systematic monitoring are needed to secure food safety and human health.


Assuntos
Exposição Dietética/análise , Contaminação de Alimentos/análise , Micotoxinas/análise , Zea mays/química , Aflatoxinas/análise , China , Exposição Dietética/efeitos adversos , Inocuidade dos Alimentos/métodos , Fumonisinas , Humanos , Legislação sobre Alimentos , Concentração Máxima Permitida , Micotoxinas/efeitos adversos , Tricotecenos , Zearalenona/análise
6.
Food Chem ; 271: 527-535, 2019 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-30236711

RESUMO

Transglutaminase (TGase) catalyzing crosslinking between intra- and inter-chain glutamine and lysine peptide residues has been used for modifying protein's structure. However, its enzymatic performance on albuminoids such as collagen was still not completely illustrated. Herein, we investigated the crosslinking efficiency of films preheated at different temperatures and estimated its physicochemical properties. The electrophoresis results showed that the extracted collagen had typical triple helix structure but reduced and even disappeared as temperature increased. Accordingly, X-ray diffraction (XRD) indicated that the amount of triple helices decreased, corresponding to the decreases in thermal stability and mechanical properties of films. TGase crosslinking decreased the thickness of all films, while mechanical properties and thermal stability had a significant improvement especially at 45 °C and 65 °C. With the proper equilibrium of denature temperature and TGase crosslinking, the tailored film-forming properties of collagen can offer a potential to engineer collagenic material for biodegradable and edible packaging applications.


Assuntos
Colágeno/química , Reagentes para Ligações Cruzadas/química , Temperatura Ambiente , Transglutaminases/química , Transglutaminases/metabolismo , Difração de Raios X
7.
J Trop Pediatr ; 64(1): 60-66, 2018 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-28419373

RESUMO

Background: Childhood obesity has increased dramatically during the past decades; however, data on the prevalence of morbid obesity is limited. The present study examined the prevalent trends in morbid obesity among children and adolescents during the past 19 years (1995-2014) in Shandong, China. Methods: Data for this study were obtained from five cross-sectional surveys (1995, 2000, 2005, 2010 and 2014) of schoolchildren in Shandong Province, China. A total of 41 500 students aged 7-18 years were included in this study. Body mass index cutoffs recommended by the International Obesity Task Force were used to define morbid obesity. Results: The prevalence of morbid obesity was increasing continuously during the past 19 years (1995-2014), from 0.25% for boys and 0.11% for girls in 1995 to 2.73% for boys and 1.29% for girls in 2014. Boys had higher prevalence of morbid obesity than girls (p<0.01). Regional socioeconomic status (SES) inequalities in morbid obesity were observed; children and adolescents from high SES district had a rapid increase in the prevalence of morbid obesity than their counterparts from moderate SES and low SES districts in the past 19 years. Conclusion: Although the current prevalence of morbid obesity was at a relatively low level, a continuous increasing trend was observed between 1995 and 2014. We should not relax our vigilance, and policymakers and experts should pay more attention to the monitoring and prevention of morbid obesity among children and adolescents in the future decades.


Assuntos
Obesidade Mórbida/epidemiologia , Adolescente , Índice de Massa Corporal , Criança , China/epidemiologia , Estudos Transversais , Feminino , Humanos , Masculino , Prevalência , Classe Social
8.
J Neurosci ; 38(3): 691-709, 2018 01 17.
Artigo em Inglês | MEDLINE | ID: mdl-29192127

RESUMO

Combining sensory inputs over space and time is fundamental to vision. Population receptive field models have been successful in characterizing spatial encoding throughout the human visual pathways. A parallel question, how visual areas in the human brain process information distributed over time, has received less attention. One challenge is that the most widely used neuroimaging method, fMRI, has coarse temporal resolution compared with the time-scale of neural dynamics. Here, via carefully controlled temporally modulated stimuli, we show that information about temporal processing can be readily derived from fMRI signal amplitudes in male and female subjects. We find that all visual areas exhibit subadditive summation, whereby responses to longer stimuli are less than the linear prediction from briefer stimuli. We also find fMRI evidence that the neural response to two stimuli is reduced for brief interstimulus intervals (indicating adaptation). These effects are more pronounced in visual areas anterior to V1-V3. Finally, we develop a general model that shows how these effects can be captured with two simple operations: temporal summation followed by a compressive nonlinearity. This model operates for arbitrary temporal stimulation patterns and provides a simple and interpretable set of computations that can be used to characterize neural response properties across the visual hierarchy. Importantly, compressive temporal summation directly parallels earlier findings of compressive spatial summation in visual cortex describing responses to stimuli distributed across space. This indicates that, for space and time, cortex uses a similar processing strategy to achieve higher-level and increasingly invariant representations of the visual world.SIGNIFICANCE STATEMENT Combining sensory inputs over time is fundamental to seeing. Two important temporal phenomena are summation, the accumulation of sensory inputs over time, and adaptation, a response reduction for repeated or sustained stimuli. We investigated these phenomena in the human visual system using fMRI. We built predictive models that operate on arbitrary temporal patterns of stimulation using two simple computations: temporal summation followed by a compressive nonlinearity. Our new temporal compressive summation model captures (1) subadditive temporal summation, and (2) adaptation. We show that the model accounts for systematic differences in these phenomena across visual areas. Finally, we show that for space and time, the visual system uses a similar strategy to achieve increasingly invariant representations of the visual world.


Assuntos
Modelos Neurológicos , Córtex Visual/fisiologia , Percepção Visual/fisiologia , Adulto , Mapeamento Encefálico/métodos , Feminino , Humanos , Imagem por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Tempo , Adulto Jovem
9.
Sci Rep ; 7(1): 9772, 2017 08 29.
Artigo em Inglês | MEDLINE | ID: mdl-28852170

RESUMO

To investigate the concentrations of rare earth elements in cereals and assess human health risk through cereal consumption, a total of 327 cereal samples were collected from rare earth mining area and control area in Shandong, China. The contents of 14 rare earth elements were determined by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). The medians of total rare earth elements in cereals from mining and control areas were 74.22 µg/kg and 47.83 µg/kg, respectively, and the difference was statistically significant (P < 0.05). The wheat had the highest rare earth elements concentrations (109.39 µg/kg and 77.96 µg/kg for mining and control areas, respectively) and maize had the lowest rare earth elements concentrations (42.88 µg/kg and 30.25 µg/kg for mining and control areas, respectively). The rare earth elements distribution patterns for both areas were characterized by enrichment of light rare earth elements. The health risk assessment demonstrated that the estimated daily intakes of rare earth elements through cereal consumption were considerably lower than the acceptable daily intake (70 µg/kg bw). The damage to adults can be neglected, but more attention should be paid to the effects of continuous exposure to rare earth elements on children.


Assuntos
Grão Comestível/química , Meio Ambiente , Metais Terras Raras/análise , Mineração , Medição de Risco , China , Humanos
10.
Int J Occup Environ Health ; 23(1): 11-19, 2017 01.
Artigo em Inglês | MEDLINE | ID: mdl-28145155

RESUMO

BACKGROUND: Zinc oxide nanoparticles (ZnO NPs) are increasingly being used in industry. OBJECTIVE: To evaluate the acute toxicology of ZnO NPs in Mice. METHODS: ZnO NPs were intratracheally instilled into mice at different dose (200, 400, 800 µg/kg), which was 1, 2, or 4 times of accumulative intake in one week according to the threshold limit value. Acute toxicity was assessed by animal mortality, organ/body weight ratios, hematology, blood biochemistry, and histopathology as well as by the determination of cells, proteins, and lactate dehydrogenase activity in bronchoalveolar lavage fluid. RESULTS: Exposure to ZnO NPs also resulted in bodyweight loss and a higher level of total cell number, total protein, and hydroxyproline content in BALF. Nitric oxide and malondialdehyde levels in the lung homogenates were also increased. In addition, inflammatory and hyperplastic changes in the lungs were observed. CONCLUSION: Threshold limit value (5 mg/m3) may unfit for ZnO NPs.


Assuntos
Pulmão , Nanopartículas Metálicas/toxicidade , Fibrose Pulmonar , Óxido de Zinco/toxicidade , Administração por Inalação , Animais , Pulmão/efeitos dos fármacos , Pulmão/patologia , Masculino , Nanopartículas Metálicas/administração & dosagem , Camundongos , Camundongos Endogâmicos ICR , Fibrose Pulmonar/induzido quimicamente , Fibrose Pulmonar/patologia , Óxido de Zinco/administração & dosagem
11.
Chemosphere ; 168: 578-582, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-27842718

RESUMO

To investigate the concentrations of rare earth elements in vegetables and assess human health risk through vegetable consumption, a total of 301 vegetable samples were collected from mining area and control area in Shandong, China. The contents of 14 rare earth elements were determined by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). The total rare earth elements in vegetables from mining and control areas were 94.08 µg kg-1 and 38.67 µg kg-1, respectively, and the difference was statistically significant (p < 0.05). The leaf vegetable had the highest rare earth elements concentration (984.24 µg kg-1 and 81.24 µg kg-1 for mining and control areas, respectively) and gourd vegetable had the lowest rare earth elements concentration (37.34 µg kg-1 and 24.63 µg kg-1 for mining and control areas, respectively). For both areas, the rare earth elements concentration in vegetables declined in the order of leaf vegetable > taproot vegetable > alliaceous vegetable > gourd vegetable. The rare earth elements distribution patterns for both areas were characterized by enrichment of light rare earth elements. The health risk assessment demonstrated that the estimated daily intakes (0.69 µg kg-1 d-1 and 0.28 µg kg-1 d-1 for mining and control areas, respectively) of rare earth elements through vegetable consumption were significantly lower than the acceptable daily intake (70 µg kg-1 d-1). The damage to adults can be neglected, but more attention should be paid to the effects of continuous exposure to low levels of rare earth elements on children.


Assuntos
Contaminação de Alimentos/análise , Metais Terras Raras/análise , Mineração , Poluentes do Solo/análise , Verduras/química , Adulto , Criança , China , Humanos , Nível de Efeito Adverso não Observado , Medição de Risco
12.
Food Addit Contam Part B Surveill ; 9(3): 170-5, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26892316

RESUMO

In the present study, the occurrence and contamination levels of eight mycotoxins were investigated in wheat flour samples (n = 359) from Shandong Province of China. Samples were determined using a multi-mycotoxin method based on isotope dilution ultrahigh performance liquid chromatography-tandem mass spectrometry. The results indicated that the most frequently found mycotoxins were deoxynivalenol (DON) (97.2%), nivalenol (40.4%) and deoxynivalenol-3-glucoside (33.4%), and mean contamination levels in positive samples were 86.7, 3.55 and 3.34 µg kg(-1), respectively. The obtained data were further used to estimate the daily intake of the local population, and indicated that wheat flour consumption contributes little to DON exposure. However, with the aim to keep the contamination levels under control and to establish a more precise evaluation of the mycotoxin burden in Shandong Province, more sample data from different harvest years and seasons are needed in the future.


Assuntos
Carcinógenos Ambientais/análise , Dieta/efeitos adversos , Farinha/análise , Contaminação de Alimentos , Micotoxinas/análise , Adulto , Carcinógenos Ambientais/toxicidade , China , Cromatografia Líquida de Alta Pressão , Dieta/etnologia , Inquéritos sobre Dietas , Farinha/efeitos adversos , Farinha/economia , Inspeção de Alimentos/métodos , Glucosídeos/análise , Glucosídeos/toxicidade , Humanos , Técnicas de Diluição do Indicador , Limite de Detecção , Micotoxinas/toxicidade , Reprodutibilidade dos Testes , Sementes/efeitos adversos , Sementes/química , Espectrometria de Massas por Ionização por Electrospray , Espectrometria de Massas em Tandem , Tricotecenos/análise , Tricotecenos/toxicidade , Triticum/efeitos adversos , Triticum/química
16.
Artigo em Chinês | MEDLINE | ID: mdl-25169239

RESUMO

OBJECTIVE: Risk assessment and risk control for occupational exposure to chemical toxicants were performed on an isophorone nitrile device with an annual production of 5,000 tons, based on improved Singaporean semi-quantitative risk assessment method, with consideration of actual situation in China and in the present project. METHODS: With the use of engineering analysis and identification of occupational hazards in the improved Singaporean semi-quantitative risk assessment method, hazard rating (HR) and risk assessment were performed on chemical toxicants from an isophorone nitrile device with an annual production of 5,000 tons. RESULTS: The chemical toxicants in the isophorone nitrile device were mainly isophorone, hydrocyanic acid, methanol, phosphoric acid, sodium hydroxide, and sodium cyanide; the HR values were mild hazard (2), extreme hazard (5), mild hazard (2), mild hazard (2), moderate hazard (3), and extreme hazard (5), respectively, and the corresponding exposure rating (ER) values were 2.09, 2.72, 2.76, 1.68, 2.0, and 1.59, respectively. The risk of chemical toxicants in this project was assessed according to the formula Risk = [HR×ER](1/2). Hydrocyanic acid was determined as high risk, sodium hydroxide and sodium cyanide as medium risk, and isophorone, methanol, and phosphoric acid as low risk. Priority in handling of risks was determined by risk rating. The table of risk control measure was established for pre-assessment of occupational hazards. CONCLUSION: With risk assessment in this study, we concluded that the isophorone nitrile device with 5,000 ton annual production was a high-occupational hazard device. This device is a project of extreme occupational hazard. The improved Singaporean semi-quantitative risk assessment method is a scientific and applicable method, and is especially suitable for pre-evaluation of on-site project with no analogy.


Assuntos
Cicloexanonas , Nitrilos , Exposição Ocupacional/prevenção & controle , Humanos , Medição de Risco
18.
Ann Hum Biol ; 41(5): 383-8, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24617792

RESUMO

BACKGROUND: Anthropometric indices such as waist circumference (WC), waist-to-height ratio (WHtR) and waist-hip ratio (WHR) have been recognized as useful alternatives to visceral fat measurement in epidemiological studies. WHR has been used extensively in adults. However, there are very few published data for WHR among children and adolescents. AIM: The present study examined the distribution of WHR and the relationship with blood pressure (BP) among children and adolescents in Shandong, PR China. SUBJECTS AND METHODS: Data for this study were obtained from a large cross-sectional survey of schoolchildren carried out in 2010. A total of 38,822 students (19,456 boys and 19,366 girls) aged 7-17 years participated in this study. WC, Hip circumference (HC), systolic blood pressure (SBP) and diastolic blood pressure (DBP) of all subjects were measured; WHR was calculated as WC divided by HC. Abdominal obesity was defined by previously published WHR references based on Chinese children and adolescents living in Beijing. All subjects were divided into two groups (group 1 with WHR <85th; group 2 with WHR ≥85th) according to the percentiles of WHR and comparisons of the SBP and DBP between the two groups were made. RESULTS: The WHR levels in Shandong boys and girls were lower than those from German and Pakistani. The overall prevalence of abdominal obesity was 9.53% (95% CI = 9.12-9.95%) for boys and 9.82% (95% CI = 9.40-10.24%) for girls, no statistical differences between the two genders were observed (p > 0.05). In both boys and girls, the Z-scores of SBP and DBP were all significantly lower in group 1 than in group 2 (p < 0.01), indicating that children and adolescents with high WHR tended to have higher BP values. CONCLUSION: WHR is useful in identifying children and adolescents at risk of developing high BP. These findings, together with the known tracking of BP from adolescence into adulthood, highlight the importance of preventing overweight and obesity among children and adolescents in order to prevent the development of hypertension in adults.


Assuntos
Pressão Sanguínea , Obesidade Pediátrica/epidemiologia , Relação Cintura-Quadril , Adolescente , Criança , China/epidemiologia , Estudos Transversais , Feminino , Humanos , Masculino , Prevalência
19.
Zhonghua Liu Xing Bing Xue Za Zhi ; 34(2): 125-8, 2013 Feb.
Artigo em Chinês | MEDLINE | ID: mdl-23751464

RESUMO

OBJECTIVE: To study the development of waist circumference (WC) and hip circumference (HC) in children and adolescents in Shandong province, and to provide scientific data for developing related reference values for screening central obesity in Chinese children and adolescents. METHODS: Using data from 'Student physical fitness and health surveillance 2010 project' in Shandong province, a total of 42 275 students aged 7 - 18 years were selected to participate in this study. WC, HC, waist-to-hip ratio (WHR) and wrist-to-stature ratio (WSR) of subjects were measured. Comparison of data from the current study and other similar studies was made. RESULTS: The mean values of WC increased with age, and boys all significantly higher than girls in all age categories (P < 0.01). There were two crosses on gender regarding the HC curves: before the age of 11 years, with mean HC higher in boys than in girls, but girls were higher than boys between the age of 12 to 14 while boys were also higher than girls after the age of 15 years. The 50(th) percentiles (P(50)) of WC of children and adolescents aged 7 to 18 years in Shandong appeared above the figures by 1.3 - 3.1 cm (boys) and 1.2 - 2.0 cm (girls) from 15 provinces in China as well as above the data from Hong Kong by 1.9 - 5.4 cm (boys) and 2.0 - 6.5 cm (girls), respectively. Overall, 20.20% of the boys and 16.57% of the girls had a WC of ≥ 90(th) percentile and 15.73% and 7.38% of the boys and girls had a WHtR of ≥ 0.5 which both showed significant differences between genders (P < 0.01). CONCLUSION: Children and adolescents from Shandong province had a high level of WC.


Assuntos
Índice de Massa Corporal , Desenvolvimento Infantil , Estudantes , Adolescente , Criança , China/epidemiologia , Feminino , Humanos , Masculino , Circunferência da Cintura , Relação Cintura-Quadril
20.
Zhonghua Liu Xing Bing Xue Za Zhi ; 34(11): 1068-70, 2013 Nov.
Artigo em Chinês | MEDLINE | ID: mdl-24517935

RESUMO

OBJECTIVE: To study the prevalence and characteristics of blood pressure (BP) among children and adolescents at normal weight but with abdominal obesity. METHODS: Using data from the 'Student physical fitness and health surveillance 2010 project' in Shandong province, a total of 38 816 students aged 7-17 years were selected to participate in this study. Stature, body weight, waist circumference(WC), systolic blood pressure(SBP)and diastolic blood pressure(DBP) of these subjects were measured. Body weight status and abdominal obesity were defined by body mass index (BMI) and WC, respectively. RESULTS: In total, the proportions of thinness, normal weight, overweight and obesity defined by BMI were 5.37%, 72.47%, 12.92% and 9.24% respectively. 5.86% of the children and adolescents with normal weight had abdominal obesity, with normal weighted girls (7.19%) having higher prevalence of abdominal obesity than boys(4.33%)(P < 0.01). The Z-scores of SBP and DBP for both boys and girls were all significantly higher in the normal weight but with abdominal obesity groups than in both normal weight and WC groups (P < 0.01). CONCLUSION: Children and adolescents under normal weight but with abdominal obesity had higher BP level need to be identified and considered as high-risk individuals. Related intervention programs should also be targeted to this population.


Assuntos
Obesidade Abdominal/epidemiologia , Obesidade Abdominal/fisiopatologia , Adolescente , Pressão Sanguínea , Índice de Massa Corporal , Peso Corporal , Criança , China/epidemiologia , Feminino , Humanos , Masculino , Estudantes , Circunferência da Cintura
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