Characterization of a group of children with eosinophilic esophagitis in Cali, Colombia

Purpose: Eosinophilic esophagitis (EoE) is an immunologically mediated chronic disease of the gastrointestinal tract. The objective of this study was to clinically and demographically describe a child population with EoE diagnosed in a high-complexity hospital in Cali, Colombia. Methods: A retrospective study was carried out. The clinical histories of patients between 0 and 18 years with clinical suspicion and a histological diagnosis of EoE were analyzed. All patients underwent an allergy study, either by measurement of specific immunoglobulin (Ig) E and/or an intraepidermal skin-prick test. Results: Thirty-five patients were included in the study, of which 21 (60%) women. The median age was 8 years (interquartile range [IQR] 5–12), and the age of onset of symptoms was 5 years (IQR 2–10). Thirty patients (85.7%) reported a history of allergic disease, with rhinitis being the most frequent (n = 25, 71.4%). Only one patient reported with food allergy mediated by IgE. The main symptoms in patients included abdominal pain (17 [48.6%]), refractory gastroesophageal reflux (16 [45.7%]), and choking (9 [25.7%]). Upper gastrointestinal endoscopy was normal in 10 patients (38.5%). The median number of eosinophils in the biopsy was 42 (IQR 31–92). Allergenic sensitization was verified in 25 of 35 patients (71.4%). Of these, dust mite allergy was positive in 21 patients (84%), while the most frequent food allergy was toward cow’s milk, in five patients (31.3%). Conclusions: The majority of patients with EoE were females. The most frequent symptom was abdominal pain. Endoscopic abnormalities were also observed frequently, and the prevalence of other allergic diseases (especially rhinitis) and allergenic sensitization (especially to mites) was high (AU)

Characterization of a group of children with eosinophilic esophagitis in Cali, Colombia.

PURPOSE: Eosinophilic esophagitis (EoE) is an immunologically mediated chronic disease of the gastrointestinal tract. The objective of this study was to clinically and demographically describe a child population with EoE diagnosed in a high-complexity hospital in Cali, Colombia. METHODS: A retrospective study was carried out. The clinical histories of patients between 0 and 18 years with clinical suspicion and a histological diagnosis of EoE were analyzed. All patients underwent an allergy study, either by measurement of specific immunoglobulin (Ig) E and/or an intraepidermal skin-prick test. RESULTS: Thirty-five patients were included in the study, of which 21 (60%) women. The median age was 8 years (interquartile range [IQR] 5-12), and the age of onset of symptoms was 5 years (IQR 2-10). Thirty patients (85.7%) reported a history of allergic disease, with rhinitis being the most frequent (n = 25, 71.4%). Only one patient reported with food allergy mediated by IgE. The main symptoms in patients included abdominal pain (17 [48.6%]), refractory gastroesophageal reflux (16 [45.7%]), and choking (9 [25.7%]). Upper gastrointestinal endoscopy was normal in 10 patients (38.5%). The median number of eosinophils in the biopsy was 42 (IQR 31-92). Allergenic sensitization was verified in 25 of 35 patients (71.4%). Of these, dust mite allergy was positive in 21 patients (84%), while the most frequent food allergy was toward cow's milk, in five patients (31.3%). CONCLUSIONS: The majority of patients with EoE were females. The most frequent symptom was abdominal pain. Endoscopic abnormalities were also observed frequently, and the prevalence of other allergic diseases (especially rhinitis) and allergenic sensitization (especially to mites) was high.

Fundamentos pedagógicos y didácticos de la enseñanza de las técnicas histológicas básicas en la formación de posgrado / Pedagogic and didactic fundamentals for teaching basic histologic techniques in posgraduate education

Hace algunos años se observa una progresiva demanda del perfeccionamiento en el marco del proceso de enseñanza aprendizaje de la especialidad de Histología, debido a que el progreso tecnológico ha incrementado de modo considerable el rango de las opciones de los medios a disposición de los estudiantes y profesores. Por lo tanto la presente investigación tiene como objetivo conocer los antecedentes para la asignatura Técnicas Histológicas Básicas II, el cual se sustenta en un sistema teórico que fundamenta el proceso de enseñanza aprendizaje, la definición del objeto de la asignatura y del modo de actuación profesional para las especialidades Histología, Embriología y Anatomía Patológica en el contexto nacional e internacional. Se concluye que una de las funciones fundamentales de la Universidad como órgano encargado de mantener y desarrollar la cultura social es la formación de posgrado, la cual se considera como el proceso formativo para la creación del conocimiento a modo de valor. Entre sus funciones básicas está desarrollar la investigación tecnológica y cultural con el objetivo de promover el desarrollo sostenible y garantizar la autogestión del aprendizaje y la socialización del conocimiento(AU)

Some years ago, a progressive demand for improvement has been observed within the framework of the teaching-learning process of the Histology specialty, because technological progress has considerably increased the range of media options available for students and teachers. Therefore, the objective of this research is to know the antecedents for the subject Basic Histological Techniques II, which is based on a theoretical system that supports the teaching-learning process, the definition of the object within the subject field, and the way of professional performance for the specialties Histology, Embryology and Pathological Anatomy in the national and international context. As the institution responsible for maintaining and developing social culture, one of the fundamental functions of the University is concluded to be postgraduate training, which is considered the formative process for the creation of knowledge as a value. Its basic functions include to develop technological and cultural research with the aim of promoting sustainable development and to guarantee self-management of learning and the socialization of knowledge(AU)