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2.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi ; 37(11): 855-857, 2019 Nov 20.
Artigo em Chinês | MEDLINE | ID: mdl-31826555

RESUMO

Objective: To analyze the clinical characteristics caused by acute poisoning by inhalation of hydrogen chloride (HCl) and to raise awareness and treatment level of the disease. Methods: The clinical manifestations, imaging features, diagnosis, treatment and prognosis of 5 patients with acute HCl poisoning were analyzed retrospectively. Results: Among the 5 cases of HCl poisoning, 2 cases were severe poisoning, 3 cases were moderate poisoning. All patients were treated with corticosteroids and symptomatic treatment, one of them was treated with venovenous extracorporeal membrane oxygenation (VV-ECMO) . All patients were recovered and discharged from hospital. Conclusion: The lung damage of acute poisoning by inhalation of HCl is rapidly progressing, early detection and timely medical treatment can obtain a better prognosis.


Assuntos
Ácido Clorídrico , Pulmão , Envenenamento , Oxigenação por Membrana Extracorpórea , Humanos , Ácido Clorídrico/envenenamento , Pulmão/efeitos dos fármacos , Envenenamento/diagnóstico , Envenenamento/terapia , Prognóstico
3.
BMJ Case Rep ; 12(10)2019 Oct 25.
Artigo em Inglês | MEDLINE | ID: mdl-31653635

RESUMO

Caustic ingestion may cause devastating injuries of the upper gastrointestinal tract and the respiratory system. We report here the successful treatment of a 37-year-old patient who ingested hydrochloric acid (100 mL; 24%) in suicidal intention. An oesophagogastroduodenoscopy revealed extensive necrosis of the gastric mucosa. A diagnostic laparoscopy was performed and confirmed the suspected transmural necrosis which resulted in a discontinuous laparoscopic gastrectomy. During the next days, the oesophageal stump was monitored through frequent oesophagoscopies and showed a good recovery. Thus, it was possible to restore continuity as early as by the sixth postoperative day performing a roux-en-y oesophagojejunostomy using the da Vinci Xi surgical robot. The patient underwent all procedures without any surgical complications and was discharged almost 1 month after initial presentation in good general condition.


Assuntos
Mucosa Gástrica/lesões , Mucosa Gástrica/cirurgia , Ácido Clorídrico/envenenamento , Adulto , Anastomose em-Y de Roux , Diagnóstico Diferencial , Gastrectomia , Humanos , Masculino , Procedimentos Cirúrgicos Minimamente Invasivos , Necrose/induzido quimicamente , Necrose/cirurgia , Procedimentos Cirúrgicos Robóticos , Tentativa de Suicídio
4.
Medicine (Baltimore) ; 96(47): e8819, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-29381986

RESUMO

RATIONALE: Electrocardiography (ECG) was used to diagnose acute coronary syndrome, but many other diseases may also result in ST segment change. We report one case of ingested hydrochloric acid present with ST segment elevation in the ECG. However, subsequent coronary angiography did not reveal significant coronary occlusion. PATIENT CONCERNS: An 83-year-old female was transferred to our emergency department (ED) from the branch hospital due to ingestion of toilet bowl cleaner containing 9.5% hydrochloric acid. She complained about chest pain and 12-lead ECG showed ST segment elevation at lead II, III, and aVF. The blood examinations revealed elevation of aspartate transaminase (69 IU/L), thrombocytopenia (62,000/µL), and acidosis (pH 7.311, pCO2 27 mm Hg, HCO3 13.3 mmol/L). Creatine kinase-MB and troponin I did not elevate then. DIAGNOSES: After transferred to our ED, coronary angiography was done within 1 hour. Angiography showed 60% stenosis in the segment 7 of left anterior descending coronary artery and 30% nonsignificant stenosis in the segment 2 of right coronary artery, with no apical ballooning. No significant lesion consistent with ST segment elevation myocardial infarction was found. INTERVENTIONS: Conservative treatment was chosen. OUTCOMES: Bradycardia was followed by cardiac arrest that developed 4 hours later. Cardiopulmonary resuscitation was applied and the patient became shock status after return of spontaneous circulation. The patient was admitted to the intensive care unit and expired on next day. LESSONS: Patients of ingested hydrochloric acid present with ST segment elevation in the ECG may not indicate coronary artery disease. This ECG finding may be a poor prognostic index in such patients.


Assuntos
Arritmias Cardíacas/induzido quimicamente , Detergentes/envenenamento , Ácido Clorídrico/envenenamento , Idoso de 80 Anos ou mais , Bradicardia/induzido quimicamente , Evolução Fatal , Feminino , Parada Cardíaca/induzido quimicamente , Humanos
5.
Pediatr Emerg Care ; 31(3): 207-8, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25738240

RESUMO

BACKGROUND: Unintentional acid ingestion is less commonly encountered than alkali ingestion. The injury develops for hours to days after ingestion and often results in progressively increasing difficulty in airway management. However, gastric perforation is rare. CASE: A 3-year-old boy presented to us with an orotonsillopharyngeal membrane and severe upper airway obstruction. Subsequently, he was diagnosed with a case of gastric perforation due to unintentional hydrochloric acid ingestion. He was treated with partial gastrectomy and feeding jejunostomy, and the recovery was good. CONCLUSIONS: Unintentional hydrochloric acid ingestion is rare in children. The manifestations masquerade many other clinical conditions, and the diagnosis is difficult in cases in which history of ingestion is not available. Treatment is symptomatic, and emergency surgery is indicated in case of gastrointestinal perforation.


Assuntos
Nutrição Enteral/métodos , Gastrectomia/métodos , Obstrução da Saída Gástrica/induzido quimicamente , Ácido Clorídrico/envenenamento , Pré-Escolar , Ingestão de Alimentos , Obstrução da Saída Gástrica/diagnóstico , Obstrução da Saída Gástrica/terapia , Humanos , Masculino , Tomografia Computadorizada por Raios X
8.
Artigo em Chinês | MEDLINE | ID: mdl-22804993

RESUMO

OBJECTIVE: To explore the changes of peripheral blood lymphocyte subsets in patients with acute hydrogen chloride gas poisoning. METHODS: When the patients were admitted or on the secondary day, the percentages of total T-cell lymphocyte subsets (CD(3)(+)CD(19)(-)), CD(4)(+)T cells (CD(3)(+)CD(4)(+)), CD(8)(+)T cells (CD(3)(+)CD(8)(+)), B cells (CD(3)(-)CD(19)(+)) and NK cells (CD(3)(-)CD(16)(+)CD(56)(+)), and the ration of CD(4)(+)/CD(8)(+) in 37 cases with acute hydrogen chloride gas poisoning and 49 healthy controls were detected with flow cytometer. RESULTS: The total T-cell percentage and total CD(4)(+)T cell percentage in 37 cases were significantly lower than those in 47 controls (P < 0.05). The percentages of NK cells and B lymphocytes in 37 cases significantly increased, as compared with controls (P < 0.05). The ration of CD(4)(+)/CD(8)(+) in 37 cases significantly decreased, as compared with controls (P < 0.05). CONCLUSION: The lymphocyte subsets in the patients with acute hydrogen chloride gas poisoning changed, which could influence the immune function of patients.


Assuntos
Intoxicação por Gás/sangue , Ácido Clorídrico/envenenamento , Subpopulações de Linfócitos/citologia , Adolescente , Adulto , Estudos de Casos e Controles , Feminino , Humanos , Contagem de Linfócitos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
9.
Hum Exp Toxicol ; 31(6): 533-8, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21665922

RESUMO

OBJECTIVE: The aim of this study was to analyse the caustic and household detergent exposure cases were admitted to the Department of Emergency Medicine at Dokuz Eylul University Hospital (EMDEU) between 1993 and 2008. METHODS: Age, sex, reason of exposure, clinical signs, rate of endoscopy in oral exposures, treatment attempts, length of hospital stay and outcome were evaluated. A chi-square test was used to analyse statistical differences. RESULTS: Caustic exposures accounted for 8.5% (1160 cases) and 4.1% (1988 cases) of all poisonings in children and adults, respectively. Female/male ratio of caustic exposure poisonings was 0.8. Most of the exposures were unintentional (158, 86.8%). Intentional exposures were common in cases between 19 and 29 years old (χ(2) = 25.685, p < 0.001). The most common caustic substance was alkaline (106, 58.3%) followed by acidic (47, 25.8%) and other household detergents (28, 15.4%). Vomiting (35.7%), nausea (14.8%) and sore throat (13.1%) were the most common clinical signs. The patients who had endoscopy, the most frequent finding was first-degree damage (58.7%). A 48-year-old man died from intentional hydrochloric acid ingestion. CONCLUSION: Because of the large number of unintentional caustic exposures, parent education is very important to decrease the caustic exposures in children.


Assuntos
Queimaduras Químicas/epidemiologia , Cáusticos/toxicidade , Detergentes/toxicidade , Serviços Médicos de Emergência/estatística & dados numéricos , Esôfago/lesões , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Queimaduras Químicas/etiologia , Criança , Pré-Escolar , Feminino , Humanos , Ácido Clorídrico/envenenamento , Lactente , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Turquia/epidemiologia , Adulto Jovem
10.
J Assoc Physicians India ; 59: 115-7, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21751650

RESUMO

The clinical spectrum of Inhalation injury can range from mild cough to a devastating ARDS. We herewith present a patient who is a goldsmith by occupation and his work consists of dissolving gold in Hydrochloric acid. He had accidentally inhaled fumes of Hydrochloric acid and presented with cough and breathlessness, later on required mechanical ventilation for ARDS and improved. This highlights the importance of not to neglect mild symptoms like cough and dyspnea in such a scenario which may have some hidden catastrophe.


Assuntos
Ácido Clorídrico/envenenamento , Respiração Artificial , Síndrome do Desconforto Respiratório do Adulto/induzido quimicamente , Acidentes de Trabalho , Antibacterianos/administração & dosagem , Tosse/etiologia , Dispneia/etiologia , Humanos , Exposição por Inalação , Masculino , Pessoa de Meia-Idade , Síndrome do Desconforto Respiratório do Adulto/terapia , Esteroides/administração & dosagem , Resultado do Tratamento
11.
Arab J Gastroenterol ; 12(2): 94-8, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21684482

RESUMO

BACKGROUND AND STUDY AIMS: Corrosive ingestion is common in Asia and it is a frequent cause of morbidity secondary to intense fibrotic reaction and stricture formation of the oesophagus. Isolated corrosive pyloric stenosis without oesophageal involvement is an uncommon phenomenon. PATIENTS AND METHODS: All consecutive patients, with corrosive ingestion in the last two decades, were reviewed and analysed. Eleven out of 201 patients with corrosive ingestion had isolated gastric outlet obstruction. RESULTS: Patients' age ranged from 11 to 29 years with a male:female ratio of 1.75:1. All patients developed pyloric stenosis following ingestion of solution of acids. Barium study revealed complete/near-complete gastric outlet obstruction in all patients. On laparotomy, there was gastric dilatation in 10 patients, who underwent posterior gastrojejunostomy, whereas the stomach was contracted in one patient, and hence anterior gastrojejunostomy was performed. Seven patients were completely relieved of their symptoms; persistent postprandial epigastric fullness and/or dyspepsia was observed in four patients whose gastrojejunostomy stoma was found adequate on barium study, suggestive of gastric motility disorder. We did not encounter gastrojejunostomy-related complication of stomal ulcer/stenosis in our patients. CONCLUSION: Isolated corrosive pyloric stenosis is not as rare as is commonly thought. Gastrojejunostomy is effective, although a fair percentage of patients appear to develop gastric motility disorder secondary to corrosive injury.


Assuntos
Cáusticos/envenenamento , Obstrução da Saída Gástrica/induzido quimicamente , Estenose Pilórica/induzido quimicamente , Piloro/lesões , Adolescente , Adulto , Queimaduras Químicas , Criança , Ingestão de Alimentos , Feminino , Derivação Gástrica , Obstrução da Saída Gástrica/cirurgia , Humanos , Ácido Clorídrico/envenenamento , Masculino , Estenose Pilórica/cirurgia , Ácidos Sulfúricos/envenenamento , Adulto Jovem
13.
Mali Med ; 25(2): 50-5, 2010.
Artigo em Francês | MEDLINE | ID: mdl-21435999

RESUMO

The multiple variant of aero-digestive foreign bodies' pathology determine many complex aspects with regard to their physiopathology, nature, and their location. The presence of a medical handicap or any particular condition could increase morbidity and expose to major risks. We are reporting here about 4 cases including an esophagus foreign body in a leprosies patient, an esophago-gastric case in a mental disorder patient, and two laryngeal-tracheal-bronchial cases during epileptic episodes. From the rarity of such accidents in an adult to their happening during a loss of consciousness or a delirious state, the clinical history is always missing. The symptoms are atypical and may misguide. The classical penetration syndrome cannot be reported. Only a clinical examination carefully conducted and completed with targeted para clinical examinations can help make early diagnosis. Endoscopy of the Esophagus on one hand, and endoscopy of the trachea and lungs on the other hand were used to extract these foreign bodies.


Assuntos
Brônquios , Epilepsia/complicações , Esôfago , Corpos Estranhos/etiologia , Glote , Hanseníase/complicações , Transtornos Psicóticos/complicações , Sistema Respiratório , Estômago , Adulto , Bronquite/etiologia , Queimaduras Químicas/complicações , Doença Crônica , Vestuário , Transtornos de Deglutição/etiologia , Prótese Dentária , Dispneia/etiologia , Ingestão de Alimentos , Endoscopia , Esofagite/complicações , Feminino , Corpos Estranhos/cirurgia , Humanos , Ácido Clorídrico/envenenamento , Masculino , Pessoa de Meia-Idade , Numismática , Aspiração Respiratória , Transtornos das Sensações/etiologia
16.
Can J Urol ; 16(3): 4701-3, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19497187

RESUMO

We report a case of a patient who developed bilateral hydroureteronephrosis from papillary necrosis secondary to ingestion of commercial toilet bowl cleaner. Eight days after her ingestion, acute renal failure prompted a renal ultrasound that showed bilateral hydroureteronephrosis. Emergent bilateral percutaneous nephrostomy tubes were placed and subsequent ureteroscopy revealed a large amount of obstructing necrotic material consistent with papillary necrosis. Ureteroscopic removal of the material and bilateral ureteral stents improved renal function. The etiology of this patient's papillary necrosis was likely due to a combination of hypovolemia, systemic acidosis from the ingestion, and direct toxicity of the substance on the renal vasculature. This case demonstrates the importance of early recognition of renal insults and the extra intestinal manifestations of toxic household ingestions.


Assuntos
Ácido Clorídrico/envenenamento , Necrose Papilar Renal/induzido quimicamente , Necrose Papilar Renal/complicações , Obstrução Ureteral/etiologia , Adolescente , Feminino , Humanos , Tentativa de Suicídio
17.
Eur J Intern Med ; 20(3): 328-30, 2009 May.
Artigo em Inglês | MEDLINE | ID: mdl-19393503

RESUMO

Castleman disease (CD) is an uncommon lymphoproliferative disorder with a unique histopathology. Generally diagnosis is not difficult for an experienced pathologist. However, not usually, some histopathological entities or tissue reactions may mimic CD. Here CD-like reaction due to toxic substance ingestion has been presented.


Assuntos
Hiperplasia do Linfonodo Gigante/etiologia , Hiperplasia do Linfonodo Gigante/patologia , Ácido Clorídrico/envenenamento , Imagem por Ressonância Magnética , Hiperplasia do Linfonodo Gigante/cirurgia , Eosinofilia/etiologia , Eosinofilia/patologia , Eosinofilia/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Tonsila Palatina/patologia , Tonsila Palatina/cirurgia , Tonsilectomia
18.
Surg Today ; 39(3): 261-4, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19280289

RESUMO

Corrosive esophagitis, caused by swallowing corrosive acid or alkali, results in cicatricial stricture of the esophagus. The stricture is often accompanied by pyloric stenosis because strong acids act synergistically with gastric juice. Resection of both the esophagus and stomach is usually necessary, and the colon or jejunum is used as an esophageal substitute. We describe how we successfully treated corrosive esophagitis associated with pyloric stenosis, by performing gastric tube interposition for the esophageal reconstruction. After resecting the injured distal part of the stomach, we pulled the pedunculated gastric tube up to the cervix after anastomosis to the jejunal limb in a Roux-en-Y fashion. This reconstruction procedure prevented excessive organ sacrifice and was minimally invasive. Thus, esophageal reconstruction by interposition using a pedunculated gastric tube can be used effectively to treat corrosive esophagitis associated with pyloric stenosis.


Assuntos
Queimaduras Químicas/cirurgia , Esofagite/induzido quimicamente , Esofagite/cirurgia , Esôfago/lesões , Ácido Clorídrico/envenenamento , Estenose Pilórica/induzido quimicamente , Estenose Pilórica/cirurgia , Anastomose em-Y de Roux , Esôfago/cirurgia , Feminino , Humanos , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Reconstrutivos , Tentativa de Suicídio
19.
J Gastrointest Surg ; 13(3): 578-80, 2009 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18446416

RESUMO

BACKGROUND: It has not been reported that ingesting large amounts of strong acid resulted in total gastrointestinal tract necrosis. Here we describe a case of a man with total gastrointestinal tract necrosis after ingestion of a considerable amount of hydrochloric acid. DISCUSSION: Computed tomography (CT) scan showed significant free air in the neck, lateral esophagus, and abdominal cavity, which indicated perforation of the esophagus and gastrointestinal tract. In addition, the abdominal CT image showed splenic subcapsular hematorna and swollen pancreatic head caused by strong acid causis. We found the entire gastrointestinal tract from stomach to rectum necrosis in the emergency exploratory laparotomy. Our case suggests that ingestion of a considerable amount (e.g., 500 mL) and concentration of strong acid could result in total gastrointestinal tract necrosis. Emergency laparotomy should be performed as early as possible to benefit this kind of patient.


Assuntos
Trato Gastrointestinal/efeitos dos fármacos , Trato Gastrointestinal/patologia , Ácido Clorídrico/envenenamento , Suicídio , Humanos , Masculino , Pessoa de Meia-Idade , Necrose/induzido quimicamente , Necrose/patologia , Necrose/cirurgia
20.
Rev Gastroenterol Peru ; 29(4): 362-6, 2009.
Artigo em Espanhol | MEDLINE | ID: mdl-20066022

RESUMO

The esophagectomy and colonic transposition by video-assisted thoracoscopy (VATS), still not recommended as a technique of choice for the treatment of benign and malignant esophagus despite good results in hospitalization, morbidity and mortality. This case describes a 24 year old male patient who swallowed muriatic acid, causing severe injuries to the esophagus and stomach. Initially, he performed jejunal transposition which subsequently are causing progressive dysphagia, readmitted 2 years later. This time surgery is performed in 2 stages: (1) rise of the ascending colon and jejunum distal to oesophageal vasculature itself, by open surgery (2) esophagectomy and colonic orthotopic transposition by VATS and posterior hypopharyngeal anastomosis in colon anterior cervical region. Patient was discharged without complications and shorter hospital stay. Currently no evidence of dysphagia, improved nutritional status and ultimately better quality of life.


Assuntos
Colo/transplante , Esofagectomia , Esôfago/lesões , Esôfago/cirurgia , Ácido Clorídrico/envenenamento , Cirurgia Torácica Vídeoassistida , Humanos , Masculino , Adulto Jovem
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