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1.
N Engl J Med ; 381(21): 2009-2019, 2019 11 21.
Artigo em Inglês | MEDLINE | ID: mdl-31693803

RESUMO

BACKGROUND: Dengue, a mosquito-borne viral disease, was designated a World Health Organization top 10 threat to global health in 2019. METHODS: We present primary efficacy data from part 1 of an ongoing phase 3 randomized trial of a tetravalent dengue vaccine candidate (TAK-003) in regions of Asia and Latin America in which the disease is endemic. Healthy children and adolescents 4 to 16 years of age were randomly assigned in a 2:1 ratio (stratified according to age category and region) to receive two doses of vaccine or placebo 3 months apart. Participants presenting with febrile illness were tested for virologically confirmed dengue by serotype-specific reverse-transcriptase polymerase chain reaction. The primary end point was overall vaccine efficacy in preventing virologically confirmed dengue caused by any dengue virus serotype. RESULTS: Of the 20,071 participants who were given at least one dose of vaccine or placebo (safety population), 19,021 (94.8%) received both injections and were included in the per-protocol analysis. The overall vaccine efficacy in the safety population was 80.9% (95% confidence interval [CI], 75.2 to 85.3; 78 cases per 13,380 [0.5 per 100 person-years] in the vaccine group vs. 199 cases per 6687 [2.5 per 100 person-years] in the placebo group). In the per-protocol analyses, vaccine efficacy was 80.2% (95% CI, 73.3 to 85.3; 61 cases of virologically confirmed dengue in the vaccine group vs. 149 cases in the placebo group), with 95.4% efficacy against dengue leading to hospitalization (95% CI, 88.4 to 98.2; 5 hospitalizations in the vaccine group vs. 53 hospitalizations in the placebo group). Planned exploratory analyses involving the 27.7% of the per-protocol population that was seronegative at baseline showed vaccine efficacy of 74.9% (95% CI, 57.0 to 85.4; 20 cases of virologically confirmed dengue in the vaccine group vs. 39 cases in the placebo group). Efficacy trends varied according to serotype. The incidence of serious adverse events was similar in the vaccine group and placebo group (3.1% and 3.8%, respectively). CONCLUSIONS: TAK-003 was efficacious against symptomatic dengue in countries in which the disease is endemic. (Funded by Takeda Vaccines; TIDES ClinicalTrials.gov number, NCT02747927.).


Assuntos
Vacinas contra Dengue/imunologia , Vírus da Dengue/imunologia , Dengue/prevenção & controle , Doenças Endêmicas/prevenção & controle , Adolescente , Américas/epidemiologia , Anticorpos Neutralizantes/sangue , Anticorpos Antivirais/sangue , Ásia/epidemiologia , Criança , Pré-Escolar , Dengue/epidemiologia , Dengue/imunologia , Vacinas contra Dengue/efeitos adversos , Vírus da Dengue/isolamento & purificação , Método Duplo-Cego , Feminino , Humanos , Incidência , Masculino , Sorogrupo , Resultado do Tratamento
2.
Zootaxa ; 4613(2): zootaxa.4613.2.12, 2019 Jun 05.
Artigo em Inglês | MEDLINE | ID: mdl-31716421

RESUMO

A taxonomic and biogeographic review of thirteen species of Encephalus Stephens 1832 and Gyrophaena Mannerheim 1830 (Aleocharinae: Gyrophaenina) of Middle Asia, with an emphasis on the fauna of Kazakhstan is provided. Gyrophaena (s.str.) aryanamensis Enushchenko, sp. nov. from Tajikistan and Kyrgyzstan, and G. (s.str.) hochhuthi Bernhauer 1908 are re-(described) and illustrated. Several synonymies are established: Encephalus (s.str.) angusticollis Sahlberg 1880 = E. solskyi Heyden 1880 (replacement name of E. kraatzi Solsky 1875; not synonym of G. nitidula (Gyllenhal 1810)), resyn., = E. torosus Eppelsheim 1893, syn. nov.; G. (s.str.) affinis Mannerheim 1830 = G. glareicola Pace 2010, syn. nov., = G. kangasi Rutanen 1994, syn. nov., = G. ranongensis Pace 2005, syn. nov., = G. rosskotheni Wüsthoff 1937, syn. nov. Illustrations of habitus and sexual characters of E. angusticollis are provided. A key to the species of Gyrophaena of the laetula group of Kazakhstan is given. Several members of Gyrophaenina are recorded for the first time: E. angusticollis, G. (s.str.) bihamata Thomson 1867, G. (s.str.) congrua Erichson 1837, G. (s.str.) joyi Wendeler 1924, G. (s.str.) obsoleta Ganglbauer 1895, G. (Phaenogyra) strictula Erichson 1839 from Kazakhstan and Middle Asia, and G. (s.str.) hochhuthi from Kazakhstan, Kyrgyzstan, and China.


Assuntos
Besouros , Distribuição Animal , Animais , Ásia , China , Cazaquistão , Quirguistão , Tadjiquistão
3.
Zootaxa ; 4560(3): zootaxa.4560.3.10, 2019 Feb 26.
Artigo em Inglês | MEDLINE | ID: mdl-31716574

RESUMO

The genus Stenichnodes is known to occur in Africa and SE Asia, and is divided into two subgenera. The sole African species belongs to Stenichnodes s. str. and is known from a single male specimen found in Chad. A specimen collected in Kenya that has spent nearly 30 years in a museum collection misidentified as a female of Parastenichnaphes cf. sumatrensis (sic!) is here recognized as a male of Stenichnodes s. str. and described as S. error sp. n.


Assuntos
Besouros , Distribuição Animal , Estruturas Animais , Animais , Ásia , Tamanho Corporal , Chade , Feminino , Quênia , Masculino , Tamanho do Órgão
4.
Zootaxa ; 4652(1): zootaxa.4652.1.12, 2019 Aug 07.
Artigo em Inglês | MEDLINE | ID: mdl-31716892

RESUMO

Neochauliodes van der Weele is the most species-rich genus of Chauliodinae (Megaloptera: Corydalidae). However, to date there are only five species of Neochauliodes recorded from India. Herein, we report a new species of Neochauliodes, N. flinti sp. nov., from northeastern India. An updated key to the species of Neochauliodes from India and adjacent regions of South Asia is also given.


Assuntos
Holometábolos , Insetos , Animais , Ásia , Índia
5.
Zootaxa ; 4612(2): zootaxa.4612.2.2, 2019 May 29.
Artigo em Inglês | MEDLINE | ID: mdl-31717064

RESUMO

Taxonomic status of the widely spread xiphydriid woodwasp Xiphydria camelus (Linné, 1758) was revised by examining morphology of 964 specimens and by molecular analysis using COI barcode sequences. Both morphological and molecular approaches indicated existence of three separate species masquerading in X. camelus of authors in East Asia. The three species were finally determined as X. camelus, X. eborata Konow, 1899, and a new species, X. albopicta. Xiphydria eborata is revived from synonymy with X. camelus and X. albopicta is described as a new species from Russia (Primorskij Kraj), China (Heilongjiang) and Japan (Hokkaido). Collection records are given for all the specimens examined.


Assuntos
Himenópteros , Animais , Ásia , Camelus , China , Código de Barras de DNA Taxonômico , Extremo Oriente , Japão , Federação Russa
6.
Zootaxa ; 4612(2): zootaxa.4612.2.4, 2019 May 29.
Artigo em Inglês | MEDLINE | ID: mdl-31717066

RESUMO

Among the currently recognized 71 extant genera of Glandulariini, Afroeudesis Franz shows an unusual distribution, with strikingly similar species known from South America, west and east Africa, and the sub-Himalayan region of Asia. Morphological studies revealed that several species placed in other genera share with Afroeudesis several unique characters, among others a symmetrical pattern of numerous setae on the frons and vertex, not known in any other Glandulariini. This 'Afroeudesis group' is here recognized to be composed of the Neotropical genera Meridaphes Jaloszynski, Stenichnoconnus Franz and Pseudoraphes Franz, the broadly distributed Afroeudesis, and the Neotropical Bicarinulodes gen. n. The last is proposed for a species previously misplaced in Microscydmus Saulcy Croissandeau, resulting in Bicarinulodes meridensis (Franz) comb. n. Bicarinulodes is most similar to Afroeudesis, but (among other differences) it lacks the apomorphy that is unique for the latter genus, the raised subtriangular 'platform' on the frons and vertex. Stenichnoconnus minor (Franz), comb. n is proposed for Euconnus minor (Franz), originally published as Venezolanoconnus minor Franz. Stenichnoconnus and Pseudoraphes are redefined and redescribed.


Assuntos
Besouros , África Oriental , Distribuição Animal , Estruturas Animais , Animais , Ásia , Tamanho Corporal , Tamanho do Órgão , América do Sul
7.
Zootaxa ; 4612(2): zootaxa.4612.2.13, 2019 May 29.
Artigo em Inglês | MEDLINE | ID: mdl-31717075

RESUMO

Although in "Fauna Sinica Insecta" 247 species of Phaneropterinae are recorded for China, there is not a single record of a species from the tribe Barbitistini. Herein, we newly record a small-sized and short-winged species of this tribe belonging to the genus Poecilimon (Fischer, 1853). We identified the species as Poecilimon intermedius (Fieber, 1853) which was collected in the Xinjiang Uygur Autonomous region, China. The records of the interesting species extend its distributional range in Asia. Detailed citations, description and necessary illustrations are provided.


Assuntos
Ortópteros , Animais , Ásia , China
8.
Zootaxa ; 4609(3): zootaxa.4609.3.7, 2019 May 24.
Artigo em Inglês | MEDLINE | ID: mdl-31717097

RESUMO

Lytta caraganae (Pallas, 1798) is widely distributed in northeast Asia. Its first instar larva hatched from eggs is described and illustrated using scanning electron microscopy (SEM). An update key to the all Lytta species based on first instar larvae is presented.


Assuntos
Besouros , Animais , Ásia , Larva , Microscopia Eletrônica de Varredura , Óvulo
9.
Zootaxa ; 4609(1): zootaxa.4609.1.11, 2019 May 22.
Artigo em Inglês | MEDLINE | ID: mdl-31717127

RESUMO

Siccia yvonneae Kühne, 2007 described as member of Lithosiini (Erebidae, Arctiinae) is transferred in the present paper to the genus Meganola Dyar, 1898 of Nolini (Nolidae, Nolinae): Meganola yvonneae (Kühne, 2007), comb. nov. Meganola yvonneae is compared to M. conspicua Dyar, 1898 type species of the genus, to M. albula ([Denis Schiffermüller], 1775) a widespread Palaearctic species and to Manoba lithosiformis László, Ronkay Ronkay, 2014 described from the Philippines as an example of a Nolinae reminding of the general habitus of Siccia from SE Asia. The adult and genitalia of the Lithosiini Siccia caffra Walker, 1854 are also figured for comparative purposes.


Assuntos
Mariposas , Animais , Ásia , Genitália , Filipinas
10.
Zootaxa ; 4608(3): zootaxa.4608.3.14, 2019 May 21.
Artigo em Inglês | MEDLINE | ID: mdl-31717143

RESUMO

The genus Lemyra Walker, 1856 is widely distributed in Asia. It is subdivided into two subgenera, Lemyra and Thyrgorina Walker, 1864 [1865] and includes more than 100 valid species, many of which were described during last three decades (Thomas 1990; Fang 1993; Inoue 1993; Tshistjakov Kishida 1994; Kirti Gill 2008; Cerný 2011; 2014; Cerny Pinratana 2009; Dubatolov 2007; Kirti Singh 2016; Saldaitis et al. 2018).


Assuntos
Mariposas , Animais , Ásia , China
11.
Zootaxa ; 4603(3): zootaxa.4603.3.1, 2019 May 10.
Artigo em Inglês | MEDLINE | ID: mdl-31717211

RESUMO

The phylogeny of the mite genus Pterygosoma Peters, 1849 (Acariformes: Pterygosomatidae), permanent parasites of lizards of the families Agamidae, Gerrhosauridae and Liolaemidae (Reptilia: Squamata), was inferred with maximum parsimony, successive weighting and implied weighting approaches based on 182 characters of 48 ingroup and 12 outgroup species. All undertaken analyses questioned the monophyly of the genus. Based on this research, Pterygosoma includes 56 mite species associated with agamas from Africa and Asia (Sauria: Agamidae). Within the genus seven natural species groups were found: mutabilis, inermis, melanum, caucasica, fimbriata, singularis and foliosetis; 13 species of the genus were not assigned to any of the groups due to their unique morphological characters. For the ligare group of the subgenus Pterygosoma s. str. (7 species) associated with the South American tree lizards from the family Liolaemidae, a new genus, Neopterygosoma gen. nov., is established. The subgenus Gerrhosaurobia Lawrence, 1959 (3 species) associated with the African plated lizards of the family Gerrhosauridae is elevated to the genus rank. Diagnoses for the three genera are presented. Historical associations are reconstructed by fitting the obtained mite tree into the host topology on the family level. Results of coevolutionary analysis highlight the coincidence of both trees. The studies suggest that the ancestor of the genus Pterygosoma switched from the hosts of Gerrhosaurobia i.e. from the plated lizards (Gerrhosauridae) to the agamas (Agamidae), and the genus Pterygosoma has its biogeographic origin in North Africa, and colonized Asia via the Arabian Peninsula, which is congruent with the historical biogeography of its hosts.


Assuntos
Lagartos , Ácaros , África , África do Norte , Animais , Arábia , Ásia , Filogenia
12.
Science ; 366(6467)2019 11 15.
Artigo em Inglês | MEDLINE | ID: mdl-31727802

RESUMO

Denk et al agree that we reported the first fossil Fagaceae from the Southern Hemisphere. We appreciate their general enthusiasm for our findings, but we reject their critiques, which we find misleading and biased. The new fossils unequivocally belong to Castanopsis, and substantial evidence supports our Southern Route to Asia hypothesis.


Assuntos
Fagaceae , Floresta Úmida , Ásia , Fósseis
13.
Zootaxa ; 4638(2): zootaxa.4638.2.1, 2019 Jul 16.
Artigo em Inglês | MEDLINE | ID: mdl-31712473

RESUMO

An integrative taxonomic analysis of the Ptychozoon lionotum group across its range in Indochina and Sundaland recovers P. lionotum sensu lato Annandale, 1905 as paraphyletic with respect to P. popaense Grismer, Wood, Thura, Grismer, Brown, Stuart, 2018a and composed of four allopatric, genetically divergent, ND2 mitochondrial lineages. Multivariate and univariate analyses of continuous and discrete morphological and color pattern characters statistically and discretely diagnose each lineage from one another and together, with maximum likelihood and Bayesian inference analyses, provide the foundation for the recognition of each lineage as a new species-hypotheses corroborated with a Generalized Mixed Yule Coalescent species delimitation analysis. Ptychozoon cicakterbang sp. nov. ranges throughout Peninsular Malaysia to Pulau Natuna Besar, Indonesia; P. kabkaebin sp. nov. is endemic to northern and central Laos; and P. tokehos sp. nov. ranges from southern Thailand south of the Isthmus of Kra northward to Chiang Mai, fringing the Chao Phraya Basin and ranging southward through Cambodia to southern Vietnam. Ptychozoon lionotum sensu stricto ranges from northwestern Laos through southern Myanmar to eastern India. The phylogeographic structure within each species varies considerably with P. lionotum s.s. showing no genetic divergence across its 1,100 km range compared to P. cicakterbang sp. nov. showing upwards of 8.2% sequence divergence between syntopic individuals. Significant phylogeographic structure exists within P. tokehos sp. nov. and increased sampling throughout Thailand may require additional taxonomic changes within this species.


Assuntos
Lagartos , Filogenia , Animais , Ásia , Teorema de Bayes , Variação Genética , Indochina
14.
Zootaxa ; 4638(2): zootaxa.4638.2.8, 2019 Jul 16.
Artigo em Inglês | MEDLINE | ID: mdl-31712480

RESUMO

Symphytognatha Hickman, 1931 was originally erected by Hickman (1931) as the type genus of the spider family Symphytognathidae. Forster and Platnick (1977) reviewed the family and proposed a diagnosis for Symphytognatha: almost completely fused chelicerae with a visible suture line and multidentate superior claws on legs I and II (but not on legs III and IV). Currently this genus contains 14 species (World Spider Catalog 2019), mainly widespread in South Africa (Griswold 1987), Oceania (Hickman 1931, Forster Platnick 1977, Platnick 1979, Harvey 1992, 2001), and Central and South America (Balogh Loksa 1968, Forster Platnick 1977, Georgescu 1988, Brescovit, Álvares Lopes 2004, Dupérré Tapia 2017).


Assuntos
Aranhas , Distribuição Animal , Estruturas Animais , Animais , Ásia , África do Sul , América do Sul
15.
Zootaxa ; 4594(1): zootaxa.4594.1.1, 2019 May 03.
Artigo em Inglês | MEDLINE | ID: mdl-31716068

RESUMO

Ponera is a widespread genus of litter and soil ants. The highest diversity of the genus is found in Asia, with Taiwan and Japan being two of the most species-rich regions. Here, we systematically review the taxonomy of the 16 Taiwanese and Japanese Ponera species, two of which are new species from Taiwan: Ponera terayamai sp. n. and P. wui sp. n. A new key for Ponera species of East Asia is presented.


Assuntos
Formigas , Animais , Ásia , Extremo Oriente , Japão , Taiwan
16.
Zootaxa ; 4590(2): zootaxa.4590.2.2, 2019 Apr 26.
Artigo em Inglês | MEDLINE | ID: mdl-31716092

RESUMO

Character state variation among species within Dendrothrips Uzel is discussed, with seven species-groups suggested based on sculpture of body and fore wing surface. Sexual dimorphism in pronotal sculpture and posteroangular setae is described in D. magnoliae. The major host plants of several species are indicated, and the wide distribution across Asia of some species emphasised. Species of Dendrothrips from China are reviewed, D. octosparsus sp. n. is described from Oleaceae, and a key presented to the ten species from China. Two species previously known only from Japan, D. magnoliae Kudô and D. latimaculatus Nonaka Okajima, are newly recorded from China along with the first description of their males. The male of D. homalii Zhang Tong is described and illustrated. The record from China of D. mendax Bhatti is considered a misidentification of D. latimaculatus. D. schmiae Kudô is synonymized with D. minowai Priesner.


Assuntos
Tisanópteros , Distribuição Animal , Animais , Ásia , China , Japão , Masculino , Caracteres Sexuais
17.
Zootaxa ; 4618(1): zootaxa.4618.1.1, 2019 Jun 17.
Artigo em Inglês | MEDLINE | ID: mdl-31716326

RESUMO

The Barsine hypoprepioides (Walker, 1862) species-group is reviewed. Forty seven species and one subspecies belong to the species-group. Among them, fifteen species and one subspecies are new for science and described in the present paper: B. amoenissima sp. n. (Myanmar), B. selene sp. n. (Thailand and Laos), B. cao sp. n. (Thailand, Laos and Vietnam), B. speideli sp. n. (SE China, Thailand, Laos, Cambodia and Vietnam), B. mesomene sp. n. (NE India, Myanmar, China, Thailand, Laos and Vietnam), B. pandeia sp. n. (Vietnam), B. karenkensis wushipheri ssp. n. (S Taiwan), B. euryphaessa sp. n. (Vietnam), B. ivanovamariae sp. n. (Vietnam and SE China), B. eos sp. n. (Thailand), B. mene sp. n. (Thailand), B. syntypicoida sp. n. (Malaysia and Indonesia), B. dubatolovi sp. n. (The Philippines), B. visaya sp. n. (The Philippines), B. nemea sp. n. (The Philippines) and B. kishidai sp. n. (The Philippines). Eight new combinations are established: B. parameia (Rothschild, 1913), comb. n. B. takamukui (Matsumura, 1927), comb. n., B. karenkensis (Matsumura, 1930), comb. n., B. rhipiptera (Wileman West, 1928), comb. n., B. chi (Roepke, 1946), comb. nov., B. salakia (Schaus, 1922), comb. n., B. marginis (Fang, 1991), comb. nov. and B. dentata (Wileman, 1910), comb. nov. The lectotype is designated for Lithosia hypoprepioides Walker, 1862. Adults, male and female genitalia of all species are illustrated.


Assuntos
Mariposas , Animais , Ásia , Feminino , Masculino
18.
Zootaxa ; 4560(2): zootaxa.4560.2.7, 2019 Feb 25.
Artigo em Inglês | MEDLINE | ID: mdl-31716584

RESUMO

Nine new Agrilus from the Palaearctic and Oriental regions are described and illustrated: Agrilus baiocchii sp. nov. (India, Nepal, Pakistan, Thailand); A. baiyangling sp. nov. (China: Shaanxi); A. gorgan sp. nov. (Iran); A. graminis persicus ssp. nov. (Iran); A. iranopecirkai sp. nov. (Iran); A. muralis sp. nov. (China: Beijing); A. mus sp. nov. (Turkey); A. ressli sp. nov. (Iran); A. uzala sp. nov. (Russia: Primorye). The distributional range of A. araxenus Yablokov Khnzoryan, 1960 is updated.


Assuntos
Besouros , Distribuição Animal , Estruturas Animais , Animais , Ásia , Camundongos
19.
Zootaxa ; 4688(4): zootaxa.4688.4.1, 2019 Oct 24.
Artigo em Inglês | MEDLINE | ID: mdl-31719424

RESUMO

Three new species-group are established for eastern Palaearctic species of the genus Anthobium Leach, 1819: the consanguineum-group containing A. consanguineum Shavrin Smetana, sp.n. (China: Yunnan: Gaoligong Shan, Diancang Shan) and A. jaegeri Shavrin Smetana, sp.n. (Central Nepal: Kali Gandaki Valley); the crassum-group containing A. crassum Shavrin Smetana, sp.n. (China: Yunnan: Xue Shan, Haba Shan), A. crenulatum Shavrin Smetana, sp.n. (China: Yunnan: Diancang Shan), A. explanatum Shavrin Smetana, sp.n. (China: Sichuan: Gongga Shan), and A. farkaci Shavrin Smetana, sp.n. (China: Sichuan, Sabde); the reflexum-group containing A. reflexum (Reitter, 1891) (Middle Asia), A.deplanatum Shavrin Smetana, sp.n. (China: Sichuan: Erlang Shan), A. gaoligongshanense Shavrin Smetana, sp.n. (China: Yunnan: Gaoligong Shan), and A. kashmiricum (Cameron, 1941) (India: Kashmir). The species groups are defined, briefly discussed, and a key to the species included in each group is given. A lectotype is designated for Lathrimaeum reflexum Reitter, 1891. The subgenus Prionothorax Luze, 1905 is synonymized with the nominal subgenus of Anthobium. An additional species of the fusculum group is described: A. transversale Shavrin Smetana, sp.n. (China: Sichuan: Gongga Shan). The species of each species-group are (re-)described, illustrated, and their geographical distributions are mapped. Anthobium reflexum is recorded from Kyrgyzstan for the first time.


Assuntos
Besouros , Distribuição Animal , Animais , Ásia , China , Índia , Quirguistão , Nepal
20.
Zootaxa ; 4679(3): zootaxa.4679.3.8, 2019 Oct 03.
Artigo em Inglês | MEDLINE | ID: mdl-31715951

RESUMO

The 'Cephennomicrus group' of Cephenniini includes nine genera distributed mostly in SE Asia (but with some species known also from other continents, except for the Americas). Four new Oriental species are described: Cephennococcus penangensis sp. n. (W Malaysia), Cephennomicrus matangensis sp. n. (E Malaysia), Cephennomicrus selangorensis sp. n. (E Malaysia), and Trurlia nova sp. n. (E Malaysia). Cephennomicrus selangorensis is unique in having the pronotum in both sexes with broad lateral impressions demarcated from the disc by a sharp ridge, a modification slightly similar to that of only one (Australian) congener.


Assuntos
Besouros , Distribuição Animal , Estruturas Animais , Animais , Ásia , Austrália , Tamanho Corporal , Feminino , Malásia , Masculino , Tamanho do Órgão
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