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1.
San Salvador; Guillermo Alfonso Aguirre Escobar; Primera Edición; 08.10.2020. 70 p.
Não convencional em Espanhol | LILACS | ID: biblio-1122047

RESUMO

Introducción: Considerando la revisión bibliográfica realizada y los datos oficiales disponibles, se podría afirmar que El Salvador sufre un analfabetismo epidemiológico en lo referente a las principales afecciones del Sistema Estomatognático, debido entre otras múltiples causas a la carencia o limitado número de estudios con rigor científico-metodológico, que reflejen la situación global de las principales afecciones del Sistema Estomatognático en diferentes grupos etarios. Ante ello, se realiza la primera encuesta de salud bucal a nivel nacional, apegada a lo establecido metodológicamente por la OMS, criterios actualizados y considerando muestras representativas de diferentes edades, zonas geográficas del país y condiciones sociodemográficas. Objetivos: Determinar la condición de salud bucal y las necesidades de tratamiento de la población salvadoreña a través de la aplicación de diferentes indicadores epidemiológicos, caracterizar la población según condición sociodemográfica, identificar sus conocimientos y prácticas en salud bucal. Metodología: El diseño corresponde a un estudio observacional, descriptivo y transversal, característico de una encuesta de salud oral y metodología Pathfinder según OMS. El trabajo de campo se efectuó en 24 municipios de El Salvador, entre 2016 y 2017. La muestra total fue de 3881 salvadoreños, de ambos sexos, distribuidos en seis grupos etarios (2-5, 5-6, 6-12, 13-17,18-30, 31-45 y 60 a más), siguiendo la técnica de muestreo estratificado por conglomerados sugerida por el Manual de Encuestas de Salud Bucodental de la OMS, 2013. Los datos fueron analizados en SPSS V25, donde fueron calculadas las medias, desviaciones estándar y porcentajes de las variables analizadas.


Assuntos
Humanos , Inquéritos de Saúde Bucal , Saúde Bucal , Inquéritos Epidemiológicos , Índice de Higiene Oral , Índice Periodontal , Cárie Dentária , Fluorose Dentária
2.
J Indian Soc Pedod Prev Dent ; 38(3): 280-288, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33004727

RESUMO

Background/Introduction: Adolescents are the most vulnerable population to initiate tobacco use. It is now well established that most of the adult users of tobacco start tobacco use in their childhood or adolescence. Aim: The purpose of this study is to compare and evaluate the Group Motivational Therapy (GMT) and Individualised Motivational therapy (IMT) for tobacco cessation in adolescents. Methodology: Oral screening was done in a village named Vehra Khadi near Anand. One hundred and eight adolescents aged between 12 and 18 years were included in the study. They were randomly divided into three groups namely Group 1 - Interventional group consisting of 36 adolescents who were given GMT; Group 2 - Interventional group consisting of 36 adolescents who were given IMT; and Group 3 -3 6 age - matched Negative control group. Hence, a total sample size of 108 was evaluated for tobacco consumption frequency, passive smoking, gingival index, and stain index and followed up for 9 months for the effect of both interventional group as well as positive control. Results: Frequency of tobacco consumption was reduced from baseline to 9 months' follow-up for both the interventional groups, which was statistically significant with <0.001 percent P value showing 84.38% change by intervention 1 and 98.30% in intervention 2. Conclusion: Group and individualized motivation serves as an effective means for tobacco cessation among adolescents. Improvement in gingival health and reduction of the tobacco consumption was observed with motivational intervention.


Assuntos
Abandono do Uso de Tabaco , Adolescente , Adulto , Criança , Humanos , Masculino , Motivação , Saúde Bucal , Índice Periodontal
3.
Shanghai Kou Qiang Yi Xue ; 29(3): 293-297, 2020 Jun.
Artigo em Chinês | MEDLINE | ID: mdl-33043347

RESUMO

PURPOSE: To explore the efficacy and safety of ornidazole combined with periodontal tissue regeneration in the treatment of periodontitis. METHODS: From March 2018 to March 2019, 100 patients with periodontitis who received treatment in the Stomatological Hospital Affiliated to the School of Medicine of Nanjing University were selected and randomly divided into the regeneration group and combined treatment group with 50 patients in each group. Patients in the regeneration group received periodontal tissue regeneration treatment, while patients in the combined treatment group received ornidazole combined periodontal tissue regeneration treatment. Related periodontal indexes including periodontal probing depth(PPD), periodontal attachment level(PAL), tooth mobility degree(MD) were measured, serum malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (gsh-px) and interleukin 10 (IL-10) and interleukin 4 (IL-4), c-reactive protein(CRP) level and immune globulin level were detected before and after treatment, the therapeutic effects and complications were recorded and compared. SPSS 21.0 software package was used for statistical analysis of the data. RESULTS: After treatment, PPD, PAL and MD levels in the combined treatment groups were significantly lower than those in the regenerative group (P<0.05). Serum MDA level in the combined treatment group was significantly lower than that in the regenerative group, SOD and gsh-px levels were significantly higher than that in the regenerative group(P<0.05). The serum levels of IgA, IgM, IgG, IgE, IL-10, IL-4 and CRP in the combined treatment group were significantly lower than those in the regenerative treatment group (P<0.05). The total effective rate of the combined treatment group was significantly higher than that of the regenerative treatment group, and the incidence of complications was significantly lower than that of the regenerative group(P<0.05). CONCLUSIONS: Ornidazole combined with periodontal tissue regeneration can improve the level of periodontal index, alleviate oxidative stress injury, improve immune function, inhibit inflammation, and has a significant therapeutic effect with high safety.


Assuntos
Metronidazol , Periodontite , Terapia Combinada , Humanos , Metronidazol/efeitos adversos , Índice Periodontal , Periodontite/tratamento farmacológico , Periodonto
4.
Shanghai Kou Qiang Yi Xue ; 29(3): 308-311, 2020 Jun.
Artigo em Chinês | MEDLINE | ID: mdl-33043350

RESUMO

PURPOSE: To evaluate the clinical efficacy of erbium-doped yttrium aluminium garnet (Er: YAG) laser in the treatment of degree II bifurcation periodontitis. METHODS: Thirty patients(60 teeth) with grade II bifurcation lesions of chronic periodontitis were enrolled in this study. One week after supergingival scaling with ultrasound, the patients were randomly divided into experimental group: subgingival scaling with ultrasound and hand instruments + Er: YAG laser irradiation in periodontal pocket; control group: the contralateral homonymous teeth were treated with subgingival scaling with ultrasound and hand instruments alone. The changes of gingival index(GI), pocket depth(PD), horizontal probing depth (HPD) and attachment loss(AL) were compared between the two groups 12 and 20 weeks after treatment. SPSS 20.0 software package was used for statistical analysis. RESULTS: Periodontal clinical indexes(GI, PD, HPD, AL) of the experimental group and control group were significantly reduced compared with baseline at 12 and 20 weeks after treatment(P<0.05). At 12 and 20 weeks after treatment, PD in the experimental group was (4.03±0.48) mm and (3.43±0.45) mm, (4.82±0.55) mm and (4.27±0.36) mm in the control group, respectively. The reduction of PD in the experimental group was significantly greater than that in the control group (P<0.05). There was no significant difference in HPD between the two groups at 12 weeks after treatment. Twenty weeks after operation, HPD in the experimental group was found to be (3.01±0.34) mm and (3.78±0.29) mm in the control group. The decrease of HPD in the experimental group was significantly greater than that in the control group (P<0.05). GI and AL of the experimental group at 12 and 20 weeks were lower than those of the control group, but the difference was not statistically significant. CONCLUSIONS: Er: YAG laser is safe and effective in the treatment of chronic periodontitis patients with grade II root bifurcation lesions with significant clinical value.


Assuntos
Periodontite Crônica , Lasers de Estado Sólido , Periodontite Crônica/terapia , Raspagem Dentária , Humanos , Lasers de Estado Sólido/uso terapêutico , Índice Periodontal , Bolsa Periodontal
5.
Shanghai Kou Qiang Yi Xue ; 29(3): 321-324, 2020 Jun.
Artigo em Chinês | MEDLINE | ID: mdl-33043353

RESUMO

PURPOSE: To evaluate the clinical effect of 65 µm glycine powder air-polishing (GPAP) by comparing with sodium hydrogen carbonate after ultrasonic scaling during subgingival polishing. METHODS: Thirty-three patients who were systematically healthy were involved in this study. After ultrasonic scaling,they were randomly assigned to the experimental group or the control group. Patients in the control group were treated with rubber cup + sodium hydrogen carbonate, while patients in the experimental group were treated only with 65 µm GPAP therapy. The clinical parameters including probing depth(PD), bleeding index(BI), plaque index(PI), staining index(SI) were recorded at baseline, 1week, 1 month, 3 months and 6 months after treatment. The results were analyzed by paired sample Wilcoxon signed-rank test with SPSS 23.0 software package. RESULTS: Both methods had good clinical effects. PD, BI, PI and SI of the two groups at 1 month, 3 months and 6 months after treatment were significantly better than those at baseline (P<0.01). SI of the experimental groups was significantly lower than that of the control group at 1 month, 3 months and 6 months after treatment(P<0.01). CONCLUSIONS: The results indicated that 65 µm GPAP may be as effective as sodium hydrogen carbonate after ultrasonic scaling in removal of dental plaque and stain. 65 µm GPAP had the advantage of reducing restaining.


Assuntos
Glicina , Ultrassom , Raspagem Dentária , Humanos , Índice Periodontal , Bolsa Periodontal
6.
Stomatologiia (Mosk) ; 99(5): 25-31, 2020.
Artigo em Russo | MEDLINE | ID: mdl-33034173

RESUMO

The number of men and women with gastroesophageal reflux disease (GERB) is increasing each year; besides, the disease seeks rejuvenation. Because the oral cavity is the initial digestive system, gastrointestinal tract diseases (GT) and associated changes in the oral cavity are closely related. THE AIM OF THE STUDY: Was to assess the dental status of patients with gastroesophageal reflux disease depending on the use of proton pump inhibitors based on the comprehensive clinical and laboratory study. The study involved 100 people aged between 35-65 years, which were divided into 3 groups (30 people - I control group, 35 - II patients with GERD who did not take proton pump inhibitors and 35 - III patients with GERD who take proton pump inhibitors). To detect patients with a predisposition to GERB, all participants in the study answered the «GRDQ¼ questionnaire. The patient was referred to a gastroenterologist for consultation, if the final score was more than 8 points. To identify the dental status of the patients, the DMFT (Decayed/Missing/Filled Teeth) index and the periodontal PI index were determined, the pH of the saliva was measured, and also the PCR (polymerase chain reaction) method was used. According to the results of the study, the final score of the GRDQ questionnaire in group II was significantly higher than that of group I and group III. The study revealed a high level of caries intensity, deterioration of periodontal and hygienic status, high prevalence of periodontal pathogens: Porphyromonas gingivalis, Prevotella intermedia and Actinobaccilus actinomecetemcomitans in patients of group II, compared with patients of group III and the control group. As a result of the study of the pH of mixed saliva, an acid shift was observed in group II. Dental status in patients with gastroesophageal reflux disease worsens.


Assuntos
Refluxo Gastroesofágico , Inibidores da Bomba de Prótons , Adulto , Idoso , Feminino , Refluxo Gastroesofágico/tratamento farmacológico , Refluxo Gastroesofágico/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Índice Periodontal , Saliva
7.
Hua Xi Kou Qiang Yi Xue Za Zhi ; 38(4): 393-397, 2020 Aug 01.
Artigo em Chinês | MEDLINE | ID: mdl-32865357

RESUMO

OBJECTIVE: To evaluate the effectiveness of periodontal endoscope as an adjuvant therapy for the non-surgical periodontal treatment of patients with severe and generalized periodontitis. METHODS: Patients (n=13) were divided into three groups: patients treated with conventional subgingival scaling and root planing (SRP) (n=7, 408 sites) (group A), SRP using periodontal endoscope (n=4, 188 sites) (group B) or SRP with periodontal endoscope 3 months after initial SRP (n=2, 142 sites) (group C). Two subgroups were divided into 2 subgroups according to PD at the baseline: 46 mm as subgroup 2. Probing depth (PD), attachment loss (AL), gingival recession (GR) and bleeding on probing (BOP) were recorded. RESULTS: The results of 3 months after treatment showed all PD, AL, and GR values in group A1 were less than those in group B1 (P<0.05), but no significant difference in BOP was found between the two groups. The decrease in PD, BOP in group B2 was more obvious than those in group A2 (P<0.000 1), and the GR values in group B2 were more than those in group A2 (P<0.000 1). But the improvement of AL showed no statistical difference between the two groups (P=0.296 8). In group C1, no significant difference in PD, AL, and GR was observed after endoscopy-assisted therapy, but it was more effective for BOP (P<0.000 1). In group C2, the improvement in PD and AL was significantly different from the improvement in SRP alone (P=0.000 5, P=0.000 2) and was accompanied by more GR (P=0.000 5). CONCLUSIONS: In non-surgical treatment of severe and generalized periodontitis, SRP can achieve good therapeutic effect on sites with 46 mm, the application of periodontal endoscopy can increase the effect, reducing PD and GR, which may be an effective supplement to the current non-surgical periodontal treatment.


Assuntos
Raspagem Dentária , Periodontite , Endoscópios , Seguimentos , Hemorragia Gengival , Humanos , Perda da Inserção Periodontal , Índice Periodontal , Bolsa Periodontal , Aplainamento Radicular , Resultado do Tratamento
8.
Artigo em Inglês | MEDLINE | ID: mdl-32925999

RESUMO

The aim of this study was to investigate which factors play a major role in the healing of Class II mandibular furcation defects treated with different surgical techniques. Twenty-five systemically healthy subjects with periodontitis stage III grade B and Class II buccal mandibular furcation involvement received one of the following open flap debridement approaches: Group 1 (n = 10), no further treatment; Group 2 (n = 10), piezoelectric contouring of the furcation roof; Group 3 (n = 9), piezoelectric contouring of the furcation roof and bone grafting; Group 4 (n = 10), piezoelectric contouring of the furcation roof and bone grafting with coronally positioned flap. Clinical and radiologic variables-bleeding on probing, probing depth (PPD), vertical and horizontal bone level (CAL and PH), gingival recession, root trunk length, radicular separation, and furcation perimeter (FP)-were evaluated at baseline and 180 days and 1 year after surgery. All clinical parameters were statistically analyzed. Surgical techniques caused clinical (CAL, PPD, PH) and radiographic (FP) improvements. Regenerative techniques and the coronally positioned flap yielded a major radiographic reduction of furcation areas. All therapies resulted in significant horizontal and vertical PPD reduction and CAL gain.


Assuntos
Defeitos da Furca/cirurgia , Regeneração Tecidual Guiada Periodontal , Humanos , Mandíbula/cirurgia , Dente Molar/cirurgia , Índice Periodontal , Resultado do Tratamento
9.
Medicine (Baltimore) ; 99(33): e21566, 2020 Aug 14.
Artigo em Inglês | MEDLINE | ID: mdl-32872008

RESUMO

Metabolic syndrome (MetS) refers to the pathological state of metabolic disorders in the body's proteins, fats, carbohydrates and other substances. MetS is a systemic metabolic disease. Periodontal disease is also a part of systemic inflammatory diseases. Among Chinese patients with middle-aged and elderly MetS, the periodontal morbidity is very high, which is due to the involvement of inflammatory mediators in the pathogenesis of MetS and periodontal disease. The latter may also be a risk factor for the former's morbidity and promotion of disease progression. At present, there are not many investigations and studies on periodontal examination data and periodontal disease prevalence of patients with MetS. Coal mine workers, especially coal mine underground workers, have different work natures and different working environments. See related report.We will collect the clinical diagnosis and treatment information of the enrolled patients. We will focus on checking the incidence of periodontal disease and recording. Establish a database, check every 10 medical records, and make corrections in time to ensure data accuracy. We will popularize oral hygiene knowledge for the included patients and guide them to brush their teeth correctly and how to use dental floss. We will perform periodontal examination on the patients' teeth by site and record the plaque index, gingival sulcus bleeding index, periodontal pocket exploration depth and other indicators. We will repeat the above inspection items and record in the second and fourth weeks of the experiment.This study will explore the correlation between periodontal disease and MetS of coal mine workers. We aim to clarify the role and mechanism of MetS in the occurrence and development of periodontal diseases, guide the prevention of periodontal diseases, and thus reduce the prevalence of periodontal diseases. TRIAL REGISTRATION:: ClinicalTrials.gov, ChiCTR2000034177, Registered on 27 June 2020.


Assuntos
Carvão Mineral , Síndrome Metabólica/epidemiologia , Mineradores/estatística & dados numéricos , Doenças Periodontais/epidemiologia , Adulto , Glicemia , Pressão Sanguínea , Índice de Massa Corporal , China/epidemiologia , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Lipídeos/sangue , Masculino , Pessoa de Meia-Idade , Higiene Bucal , Índice Periodontal , Prevalência , Fatores de Risco , Fumar/epidemiologia , Adulto Jovem
10.
Stomatologiia (Mosk) ; 99(3): 22-26, 2020.
Artigo em Russo | MEDLINE | ID: mdl-32608944

RESUMO

THE AIM: To study the effect of toothbrushes of various types on the accumulation of plaque and the proteolytic potential of gingival fluid as a pathogenic factors in long-term orthodontic treatment of patients with a distal permanent bite. MATERIAL AND METHODS: We examined 63 patients of both sexes aged 11-18 years. Orthodontic treatment was carried out for the close position of the teeth with a distal permanent bite (K07.2) and cleft palate and lips (Q37.1). Patients were divided into three groups depending on the type of toothbrush used for individual oral hygiene: group 1 (n=21) - an orthodontic manual toothbrush (Professor Persin, «Spazzolificio Piave¼, Italy); Group 2 (n=22) - an ultrasonic toothbrush (Emmi-dent, EMAG AG, Germany) and group 3 (n=20) - an electric toothbrush ("Oral-B Pro-Expert, «Procter & Gamble¼, USA). RESULTS: The amount of soft plaque was assessed by the Silness-Loe hygiene index in the subgingival region. The activity of proteolytic enzymes - elastase, collagenase, and a α-inhibitor of proteinases was determined by the enzymatic method using a XL 200 biochemical analyzer («Erba Lachema¼, Czech Republic). The accumulation of plaque in the gingival region on both jaws during the entire period of orthodontic treatment is most pronounced when using a manual brush compared to ultrasonic and electric brushes. An increase in proteolytic activity in the gingival fluid with a simultaneous decrease in antiprotease potential with long-term orthodontic treatment of patients was observed when using a manual orthodontic brush, which can be regarded as an increase in the activity of the pathogenic factors for the development of local inflammatory and destructive changes. CONCLUSION: To prevent inflammatory and destructive changes during prolonged orthodontic treatment of patients, the use of ultrasonic and electric toothbrushes in daily oral hygiene is justified.


Assuntos
Gengivite , Aparelhos Ortodônticos , Adolescente , Criança , Índice de Placa Dentária , Feminino , Humanos , Masculino , Índice Periodontal , Método Simples-Cego , Escovação Dentária
11.
Shanghai Kou Qiang Yi Xue ; 29(2): 217-220, 2020 Apr.
Artigo em Chinês | MEDLINE | ID: mdl-32626889

RESUMO

PURPOSE: To investigate the clinical effects of oral implant restoration in patients with dentition defects and the its impact on tumor necrosis factor-α(TNF-α) and interleukin-6(IL-6) levels in gingival crevicular fluid. METHODS: Eighty-four patients with dentition defects from May 2017 to August 1919 in People's Hospital of Shanghai Pudong District were enrolled and randomly divided into control group (n=42) and experimental group (n=42). Patients in the control group were repaired by routine methods,while those in the experimental group were treated with oral implant restoration. The effect of restoration was evaluated 6 months after treatment. The levels of TNF-α, IL-6 in the gingival crevicular fluid and dental function were compared between the 2 groups. The data were analyzed using SPSS 18.0 software package. RESULTS: The levels of TNF-α and IL-6 in the experimental group and the control group after treatment were significantly higher than those before treatment (P<0.05). The levels of TNF-α and IL-6 in the experimental group were significantly lower than those in the control group 6 months after treatment (P<0.05). The scores of dental function in the experimental group and the control group were significantly higher than those before treatment (P<0.05). The scores of retention, speech, chewing and aesthetics of the experimental group 6 months after treatment were significantly higher than the control group (P<0.05). The incidence of infection, pricking, post and core loosing and teeth missing in the experimental group was significantly lower than that of the control group (P<0.05). CONCLUSIONS: In the treatment of patients with dentition defects, implant restoration has little effect on the levels of TNF-α and IL-6 in gingival crevicular fluid, which is helpful to improve dental function and reduce the incidence of postoperative complications. Therefore, it is worthwhile to be popularized in clinical application.


Assuntos
Implantes Dentários , Líquido do Sulco Gengival , China , Dentição , Estética Dentária , Humanos , Interleucina-6 , Índice Periodontal , Fator de Necrose Tumoral alfa
12.
PLoS One ; 15(7): e0234659, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32614834

RESUMO

BACKGROUND: The relationship between poor oral health conditions and cognitive decline is unclear. OBJECTIVE: To examine the association between oral health and cognition in humans and rats. METHODS: In humans: a cross-sectional study was conducted. Cognitive levels were evaluated by the Mini Mental State Examination (MMSE); oral conditions were reflected by the number of missing index teeth, bleeding on probing, and probing pocket depth (PD). In rats: a ligature-induced (Lig) periodontitis model and Aß25-35-induced model of Alzheimer's disease (AD) were established; tumor necrosis factor-α (TNF-α), interleukin 1 (IL-1), interleukin 6 (IL-6), and C-reactive protein levels in the hippocampus and cerebral cortex were detected. RESULTS: MMSE scores for the number of missing index teeth ≥ 7 group were significantly lower than those in the ≤ 6 group. A negative relationship (correlation coefficient ρ = -0.310, P = 0.002) was observed between MMSE scores and number of missing index teeth. More missing index teeth and lower education levels were independent risk factors for cognitive decline. A negative relationship (correlation coefficient ρ = -0.214, P = 0.031) was observed between MMSE scores and average PD. TNF-α and IL-6 levels in the hippocampus of the Lig+AD group were significantly higher than those of the AD group. IL-1 and IL-6 levels in the cerebral cortex of the Lig+AD group were significantly higher than those of the AD group. CONCLUSION: Poor oral health conditions including more missing index teeth and higher average PD may be risk factors for cognitive decline. Periodontitis may increase inflammatory cytokines in rat models of AD.


Assuntos
Transtornos Cognitivos/etiologia , Saúde Bucal , Periodontite/complicações , Idoso , Idoso de 80 Anos ou mais , Doença de Alzheimer/etiologia , Peptídeos beta-Amiloides/toxicidade , Animais , Proteína C-Reativa/análise , Causalidade , Córtex Cerebral/química , China/epidemiologia , Transtornos Cognitivos/epidemiologia , Comorbidade , Estudos Transversais , Índice CPO , Modelos Animais de Doenças , Feminino , Hipocampo/química , Humanos , Interleucina-1/análise , Masculino , Aprendizagem em Labirinto , Testes de Estado Mental e Demência , Pessoa de Meia-Idade , Fragmentos de Peptídeos/toxicidade , Índice Periodontal , Periodontite/epidemiologia , Periodontite/etiologia , Periodontite/fisiopatologia , Distribuição Aleatória , Ratos , Ratos Sprague-Dawley , Fatores de Risco , Fator de Necrose Tumoral alfa/análise
13.
Clin Oral Implants Res ; 31(10): 946-958, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32716603

RESUMO

OBJECTIVES: This single-blinded randomized clinical trial evaluated the effect of adjuvant oral irrigation in addition to self-administered oral care on prevalence and severity of peri-implant mucositis. MATERIAL & METHODS: After randomization, patients suffering from peri-implant mucositis were assigned to the following: Group 1 (control) received oral hygiene instruction following a standardized protocol, including a sub- and supramucosal mechanical debridement. Group 2 and 3 additionally were instructed to use an oral irrigator with either water or 0.06% CHX solution. One implant per patient was considered for examination. Clinical examinations included Probing Depth, Bleeding on Probing (BOP-positive sites), and Modified Plaque and Gingival Index. A surrogate variable (mucositis severity score) was applied measuring severity of disease. Statistical analysis included linear regression models and sensitivity analysis. RESULTS: Sixty periodontally healthy patients were examined for presence and severity of peri-implant mucositis. 70% of all patients reached complete resolution of disease after 12 weeks. The prevalence of peri-implant mucositis after 12 weeks was 50% in group 1, 35% in group 2, and 5% in group 3. Average BOP-positive sites were reduced in all groups after 12 weeks (mean change from baseline: group 1: -1.5; group 2: -1.8; group 3: -2.3). CONCLUSION: Within the limits of the study, adjuvant use of an oral irrigator with 0.06% CHX in addition to mechanical biofilm removal and oral hygiene instruction can reduce the presence and severity of peri-implant mucositis after 12 weeks.


Assuntos
Implantes Dentários/efeitos adversos , Mucosite , Peri-Implantite , Estomatite/etiologia , Estomatite/terapia , Índice de Placa Dentária , Humanos , Índice Periodontal
14.
J Oral Sci ; 62(3): 281-284, 2020 Jun 23.
Artigo em Inglês | MEDLINE | ID: mdl-32493865

RESUMO

Periodontitis is an inflammatory disease involving complex tripartite cross-interactions among bacterial, host and environment factors. Heat shock proteins (Hsps) are a protein family produced in response to stress conditions. Hsps protect cells under adverse circumstances such as infection, inflammation and disease. One of the causes of periodontal disease is thought to be an imbalance in the expression of Hsps and anti-Hsp antibodies. Hsps are classified according to their molecular weight, and one of the major ones is Hsp70. In the present study, enzyme-linked immunosorbent assay was used to measure the levels of anti-Hsp70 antibody in gingival crevicular fluid (GCF) from two gingival sulci in each of nine patients with chronic periodontitis (CP): one healthy control (HC) site with a probing pocket depth (PPD) of ≤3 mm and one CP site with a PPD of >5 mm. Anti-Hsp70 antibody levels in GCF were higher at HC sites than at CP sites. Moreover, the anti-Hsp70 antibody levels were found to increase after initial periodontal therapy at both HC and CP sites. These results suggest an association of anti-Hsp70 antibody with periodontitis.


Assuntos
Periodontite Crônica , Líquido do Sulco Gengival , Proteínas de Choque Térmico HSP70 , Humanos , Japão , Índice Periodontal
15.
Shanghai Kou Qiang Yi Xue ; 29(1): 97-101, 2020 Feb.
Artigo em Chinês | MEDLINE | ID: mdl-32524131

RESUMO

PURPOSE: To investigate the expression of secreted frizzle-related protein 1 (SFRP1) and macrophage migration inhibitory factor (MIF) in elderly patients with severe periodontitis and its correlation with cognitive function. METHODS: Thirty-two elderly patients with periodontitis in Qingdao Stomatological Hospital from February 2018 to February 2019 were enrolled, and divided into two groups according to the severity: mild group and severe group. All selected subjects received periodontal examination and Montreal cognitive assessment (MoCA).The expression of SFRP1 and MIF in serum was also determined. Then the correlations among SFRP1 and MIF periodontal index and cognitive function was analyzed. The data were processed by SPSS 20.0 software package. RESULTS: The probing depth (PD), clinical attachment level (CAL), sulcus bleeding index (SBI) and gingival crevicular fluid (GCF) showed significant difference between the two groups (P<0.05). The serum levels of SFRP1 and MIF in the severe group were significantly higher than those in the mild group (P<0.05). Serum SFRP1 level was positively correlated with MIF (P<0.05). Serum SFRP1 and MIF levels were positively correlated with periodontal index (P<0.05). The MoCA score of the severe group was significantly lower than that of the mild group (P<0.05). Serum SFRP1 and MIF levels were negatively correlated with MoCA score (P<0.05). CONCLUSIONS: SFRP1 and MIF are highly expressed in serum and gingival tissues of elderly patients with severe periodontitis, and are closely related to the degree of periodontal damage. Meanwhile, patients with periodontitis may have some degree of cognitive dysfunction, and SFRP1 and MIF may affect the periodontal tissue structure through Wnt/ß-catenin signal pathway and participate in the occurrence and development of cognitive dysfunction.


Assuntos
Periodontite Crônica , Idoso , Cognição , Gengiva , Líquido do Sulco Gengival , Humanos , Peptídeos e Proteínas de Sinalização Intercelular , Oxirredutases Intramoleculares , Fatores Inibidores da Migração de Macrófagos , Proteínas de Membrana , Perda da Inserção Periodontal , Índice Periodontal
16.
Minerva Stomatol ; 69(2): 72-78, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32489087

RESUMO

BACKGROUND: The aim of this study was to evaluate the effectiveness of a tailored treatment dental program in adolescents in combination with a professional oral hygiene. METHODS: Ninety-three adolescents (43 males and 50 females; mean age: 14±1.1 years) were included in this study and Plaque Index (PI) and simplified basic periodontal examination (BPE) were measured for each patient at T0 (screening) and at T1 (after 30 days). At T0 a professional dental hygiene treatment was performed and a tailored oral hygiene instruction protocol was adopted. All data were statistically analyzed using Student's t-test and the level of significance was set at P<0.05. RESULTS: A statistically significant decrease of PI was found from T0 (2.3±0.6) to T1 (0.9±0.3) (P<0.05). Moreover, also a significant decrease (P<0.05) of BPE was observed after 30 days. Girls exhibited a higher significant BPE index improvement (0.47±0.2) in comparison to boys (0.3±0.1) at the end of the follow-up (P<0.05). CONCLUSIONS: A tailored oral hygiene instruction protocol has resulted in a decreased plaque accumulation and gingival inflammation.


Assuntos
Profilaxia Dentária , Higiene Bucal , Adolescente , Criança , Assistência Odontológica , Índice de Placa Dentária , Feminino , Humanos , Masculino , Índice Periodontal
17.
Braz Oral Res ; 34: e058, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32578801

RESUMO

In view of the epidemiological relevance of periodontal disease and chronic noncommunicable diseases, the study aimed to evaluate the relationship between them through subclinical indicators of systemic risk in a population group with healthy habits, including alcohol and tobacco abstinence. A complete periodontal examination of six sites per tooth was performed in a sample of 420 participants from the Advento study (Sao Paulo), submitted to anthropometric and laboratory evaluation. Periodontitis was defined and classified based on the Community Periodontal Index score 3 (periodontal pocket = 4-5 mm) and score 4 (periodontal pocket ≥ 6 mm). The prevalence of mild/moderate and severe periodontitis was 20% and 8.2%, respectively. Both categories of periodontal disease had significantly higher levels of triglycerides, C-reactive protein, calcium score, and calcium percentile, whereas blood glucose after tolerance test was significantly higher among people with severe periodontitis and HDL-c levels were lower (p < 0.05). Young adults with severe periodontitis had significantly higher prevalence of obesity, pre-diabetes, hypertension, and metabolic syndrome. Besides these conditions, the older adults with severe periodontitis had significantly higher prevalence of dyslipidemia and subclinical atherosclerosis. The group with periodontitis had also a higher coronary heart disease risk based on the PROCAM score (p < 0.05). The results indicated associations of periodontitis with several systemic indicators for chronic noncommunicable diseases, and highlighted the need for multiprofessional measures in the whole care of patients.


Assuntos
Doenças não Transmissíveis/epidemiologia , Periodontite/complicações , Periodontite/epidemiologia , Adulto , Idoso , Brasil/epidemiologia , Doença Crônica , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Índice Periodontal , Prevalência , Valores de Referência , Fatores de Risco , Índice de Gravidade de Doença , Fatores Socioeconômicos , Estatísticas não Paramétricas
18.
J Contemp Dent Pract ; 21(4): 431-437, 2020 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-32584282

RESUMO

AIMS: Periodontitis is one of the most widespread diseases worldwide. Many efforts have been made to increase the efficacy of periodontitis therapy as much as possible. Recently, minimally invasive nonsurgical techniques (MINST) were introduced in the periodontal field as an alternative to minimally invasive surgical techniques (MIST). This clinical audit aims to evaluate the results of MINST in the initial phase of treatment for periodontitis. MATERIALS AND METHODS: One hundred seven patients with periodontitis who were treated with MINST between 2013 and 2017 and reevaluated after 2 months were included in this clinical audit. The primary outcome analyzed was the proportion of pocket closure. The secondary outcomes were tooth extraction before active periodontal therapy, full-mouth plaque score (FMPS) change, full-mouth bleeding score (FMBS) change, average probing pocket depth (PPD) reduction, and average clinical attachment level (CAL) gain between the baseline and reevaluation values. RESULTS: A total of 2,407 teeth were included in the analysis. At the patient level, the treatment resulted in a mean pocket closure rate of 71.6 ± 15.7% for sites with an initial PPD ≥5 mm. The treatment was statistically significantly (p < 0.001) more effective with respect to the primary outcome compared with expected values reported in a recent meta-analysis (57%). The subgroup analysis revealed statistically significant differences between single and multirooted teeth and between shallow (5-6 mm) and deep pockets (≥7 mm) at the baseline. CONCLUSION: Nonsurgical periodontal therapy with MINST achieved satisfactory results that were better than expected based on the scientific literature. Single-rooted and shallow pockets showed the best proportion of pocket closure at the reevaluation after treatment. CLINICAL SIGNIFICANCE: Minimally invasive nonsurgical techniques can be the treatment of choice when approaching periodontally diseased patients with nonsurgical periodontal therapy.


Assuntos
Periodontite , Auditoria Clínica , Raspagem Dentária , Humanos , Procedimentos Cirúrgicos Minimamente Invasivos , Perda da Inserção Periodontal , Índice Periodontal , Resultado do Tratamento
19.
Artigo em Inglês | MEDLINE | ID: mdl-32559032

RESUMO

Subgingival margins are often associated with adverse periodontal reactions, such as recession and gingival inflammation. The purpose of this cross-sectional dual-center study was to evaluate the periodontal health and stability of intrasulcular margins, comparing two prosthetic margin preparations: subgingival chamfer (SC) and subgingival feather-edge (SF) with gingival curettage. Ninety-six patients with 205 crowns (buccal margin 0.5 mm into the gingival sulcus) were included in the study. SF, gingival curettage, and intrasulcular restorative margin were prepared on 109 crowns; SC was prepared on 96. Restorations were in place for a mean of 55.9 months (range: 12 months to 10 years). No significant differences were found regarding probing depth between the two groups (mean buccal: 1.6 mm; mean interproximal: 2.3 mm). Significant increased recession was present around SCs, showing a higher margin-exposure frequency (buccal: 19.8% vs 3.7%; interproximal: 5.2% vs 1.4%). SC showed 8.5 times the risk of margin exposure compared to SF, men 5.5 times compared to women, and smokers 3.7 times compared to nonsmokers. Follow-up time was not a significant factor. SC sites showed a tendency for reduced buccal bleeding on probing compared to SF sites (3.0% vs 12.1%), but no significant difference was seen in a regression model. Plaque presence increased the risk of bleeding (4.1×), and women presented a higher risk of bleeding than men (3×). Subgingival margins can provide adequate periodontal health and stability if restorative procedures are well controlled and if patients are enrolled in an adequate maintenance program. SF with intrasulcular margin favors facial soft tissue stability, as reduced gingival recession was observed. The technique should be carefully applied to promote an adequate periodontal response.


Assuntos
Coroas , Retração Gengival , Cerâmica , Estudos Transversais , Feminino , Humanos , Masculino , Índice Periodontal
20.
Hua Xi Kou Qiang Yi Xue Za Zhi ; 38(3): 290-296, 2020 Jun 01.
Artigo em Chinês | MEDLINE | ID: mdl-32573137

RESUMO

OBJECTIVE: To evaluate the clinical efficacy of clarithromycin (CLM) in the adjuvant treatment of chronic periodontitis systematically, obtain reasonable conclusions through evidence-based medicine, and provide guidance for clinical rational drug use. METHODS: Literature about CLM in the adjuvant treatment of chronic periodontitis was searched in CNKI, VIP, Wanfang, Chinese Biomedical Literature Database, PubMed, ScienceDirect, and Embase databases from inception to February 2019 using a computer. Meta-analysis was performed on the homogeneous study using RevMan 5.3 software after two independent reviewers screened the literature, evaluated the quality of the study, extracted the data, and evaluated the risk of bias in the included studies. RESULTS: Six randomized controlled trials were included in 316 subjects. The meta-analysis showed that compared with the scaling and root planning (SRP) group, the probing depth (PD) was reduced in patients with CLM and SRP [MD=-1.00, 95%CI (-1.55, -0.45), P=0.000 04]. Clinical attachment loss was obtained [MD=-0.03, 95%CI (0.43, 0.65), P<0.000 01], and the difference between the groups was statistically significant. The modified sulcus bleeding index (mSBI) was reduced [MD=-0.01, 95%CI (-0.14, 0.19), P=0.66]. No significant difference was observed between the groups, but the decrease in mSBI was more significant in CLM combined with SRP group. CONCLUSIONS: CLM combined with subgingival SRP can achieve remarkable results in treating chronic periodontitist.


Assuntos
Periodontite Crônica/tratamento farmacológico , Claritromicina , Antibacterianos/uso terapêutico , Raspagem Dentária , Humanos , Índice Periodontal , Aplainamento Radicular , Resultado do Tratamento
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