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1.
Artigo em Russo | MEDLINE | ID: mdl-33591670

RESUMO

The article presents results of measures of increasing research potential of participants of the scientific and educational medical cluster «North Caucasian¼. The measures include both organizational measures and measures of meaningful nature, i.e. union of scientific and pedagogical workers in scientific areas and their inclusion into activities of scientific schools. The steps are undertaken within the framework of scientific and educational cluster resulted in an increasing of scope of research work and incomes received from their commercialization. The integration of medical universities and medical institutes and departments of classical universities under the Ministry of Education and Science gives synergistic effect in development of innovative products.


Assuntos
Academias e Institutos , Universidades , Humanos , Instituições Acadêmicas , Faculdades de Medicina
3.
Metas enferm ; 23(10): 72-77, dic.-ene. 2021. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-ET2-7578

RESUMO

La investigación desarrollada por enfermeras en el Hospital General Universitario Gregorio Marañón (Madrid) tiene una larga trayectoria, que tuvo sus inicios en la década de 1990. La actividad docente en el área de investigación y las estructuras de apoyo a la investigación en Enfermería existentes fueron pilares básicos para el reconocimiento del Grupo de Enfermería como grupo independiente en la primera acreditación del Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM). En la actualidad, el Grupo de Enfermería está compuesto por 34 profesionales, enfermeras, matronas y fisioterapeutas, siendo doctoras el 64,7%. Las líneas de investigación se agrupan en tres ejes: Cuidados de Enfermería (Cronicidad, Críticos y Rehabilitación/Fisioterapia); Innovación y Servicios de Salud (Diseño desarrollo y usabilidad de aplicaciones, Enfermería de Práctica Avanzada y Diseño y validación de instrumentos); y Gestión (Competencias, metodología enfermera y entornos de trabajo). Desde 2011 el grupo ha obtenido un total de 288.019 (Euro) en financiación de proyectos competitivos, incluyendo la obtención de intensificaciones para la actividad investigadora y ayudas a grupos emergentes. El grupo acumula en total 187 publicaciones, habiendo publicado 105 artículos en los últimos cinco años, con un factor de impacto acumulado de 86,3. Las líneas en las que se están trabajando son la concienciación de incorporar una correcta filiación en los artículos, la búsqueda continua de colaboraciones y el reconocimiento de la participación de las enfermeras en los proyectos del hospital y del IiSGM


The research conducted by nurses at the Hospital General Universitario Gregorio Marañón (Madrid) has a long history, which started in the 1990s decade. Teaching activity in the research area and the existing structures for support to Nursing research were the basic cornerstones for the acknowledgment of the Nursing Group as an independent group at the first accreditation for the Gregorio Marañón Health Research Institute (IiSGM). Currently, the Nursing Group is formed by 34 professionals, nurses, midwives and physiotherapists; 64.7% of them are doctors. The research lines are classified along three areas: Nursing Care (Chronicity, Critical Patients and Rehabilitation / Physiotherapy); Innovation and Health Services (Design, Development and Usability of Applications, Advanced Practice Nursing, and Design and Validation of Tools); and Management (Competences; Nursing Methodology, and Work Environments). Since 2011, the group has obtained 288.019 (Euro) in total as funding for competitive projects, including achieving majors for research activity and grants for emergent groups. The group accumulates 187 publications in total; 105 articles have been published in the past 5 years, with a cumulative impact factor of 86.3. The current lines of work are: the awareness to incorporate an adequate affiliation in articles, an on-going search for collaborations, and the acknowledgement of the participation of nurses in the projects of the hospital and the IiSGM


Assuntos
Humanos , Pesquisa em Enfermagem/métodos , Cuidados de Enfermagem/métodos , Academias e Institutos , Serviços de Saúde , Equipe de Enfermagem/organização & administração , Projetos de Pesquisa
4.
Trials ; 22(1): 62, 2021 Jan 18.
Artigo em Inglês | MEDLINE | ID: mdl-33461595

RESUMO

There is a dearth of literature on best practices for managing clinical trials, and little is understood on the role of the clinical trial manager. The COVID-19 pandemic has brought this into focus, and the continuance of clinical trials worldwide has been catapulted into a state of uncertainty as countries enter lockdown to manage the spread of the virus. Participant retention is an ongoing issue in clinical trials, and the concern is that in the current pandemic environment, attrition will be an issue which could potentially jeopardise trial completion. The current situation has necessitated timely problem solving by the trial manager to ensure trials remain open, and most importantly, that participant safety, paramount in clinical trials, is monitored. The purpose of our study is to highlight key issues arising in the management of clinical trials during a pandemic from first-hand experience in a clinical research facility managing both academic and commercial clinical trials. We offer some practical guidance on solution implementation.


Assuntos
Academias e Institutos/organização & administração , Ensaios Clínicos como Assunto/organização & administração , Pessoal Administrativo , Ensaios Clínicos Fase III como Assunto , Controle de Doenças Transmissíveis , Comunicação , Coleta de Dados , Hospitais Universitários , Humanos , Irlanda , Liderança , Pacientes Desistentes do Tratamento , Seleção de Pacientes , Admissão e Escalonamento de Pessoal , Política Pública , Pesquisadores , Sujeitos da Pesquisa
5.
Health Res Policy Syst ; 19(1): 9, 2021 Jan 20.
Artigo em Inglês | MEDLINE | ID: mdl-33472643

RESUMO

BACKGROUND: The national Public Health Practice Evaluation Scheme (PHPES) is a response-mode funded evaluation programme operated by the National Institute for Health Research School for Public Health Research (NIHR SPHR). The scheme enables public health professionals to work in partnership with SPHR researchers to conduct rigorous evaluations of their interventions. Our evaluation reviewed the learning from the first five years of PHPES (2013-2017) and how this was used to implement a revised scheme within the School. METHODS: We conducted a rapid review of applications and reports from 81 PHPES projects and sampled eight projects (including unfunded) to interview one researcher and one practitioner involved in each sampled project (n = 16) in order to identify factors that influence success of applications and effective delivery and dissemination of evaluations. Findings from the review and interviews were tested in an online survey with practitioners (applicants), researchers (principal investigators [PIs]) and PHPES panel members (n = 19) to explore the relative importance of these factors. Findings from the survey were synthesised and discussed for implications at a national workshop with wider stakeholders, including public members (n = 20). RESULTS: Strengths: PHPES provides much needed resources for evaluation which often are not available locally, and produces useful evidence to understand where a programme is not delivering, which can be used to formatively develop interventions. Weaknesses: Objectives of PHPES were too narrowly focused on (cost-)effectiveness of interventions, while practitioners also valued implementation studies and process evaluations. Opportunities: PHPES provided opportunities for novel/promising but less developed ideas. More funded time to develop a protocol and ensure feasibility of the intervention prior to application could increase intervention delivery success rates. Threats: There can be tensions between researchers and practitioners, for example, on the need to show the 'success' of the intervention, on the use of existing research evidence, and the importance of generalisability of findings and of generating peer-reviewed publications. CONCLUSIONS: The success of collaborative research projects between public health practitioners (PHP) and researchers can be improved by funders being mindful of tensions related to (1) the scope of collaborations, (2) local versus national impact, and (3) increasing inequalities in access to funding. Our study and comparisons with related funding schemes demonstrate how these tensions can be successfully resolved.


Assuntos
Comportamento Cooperativo , Revisão da Pesquisa por Pares , Apoio à Pesquisa como Assunto , Faculdades de Saúde Pública , Academias e Institutos , Humanos , Entrevistas como Assunto , Projetos de Pesquisa , Reino Unido
7.
J Chromatogr A ; 1638: 461859, 2021 Feb 08.
Artigo em Inglês | MEDLINE | ID: mdl-33465582

RESUMO

In this work we present a comparison exercise between two metrological institutes for size measurement of silica nanoparticles by Asymmetrical Flow Field-Flow Fractionation (AF4) coupled to static light scattering. The work has been performed in the frame of a French inter-laboratory comparison (ILC) exercise organized by the nanoMetrology Club (CnM). The general aim of this multi-technique comparison was to improve the measurement process for each technique, after establishing a well-defined measurement procedure. The results obtained by two national metrological institutes (NMIs), the LNE (France) and the SMD (Belgium) by AF4-UV-DRI-MALS will be presented and discussed. Three different samples were characterized: the reference material ERM®-FD304, which is a suspension of colloidal silica in aqueous solution and two silica bimodal samples consisting of two populations of SiO2 nanoparticles of unknown size in aqueous solution, with different populations' ratios. The procedure for the preparation of the sample before the analysis, and main separation parameters have been previously defined between the two institutes and will be described. The principals measured parameters were the weight-average (dge_w), number-average (dge_n) and z-average (dge_z) geometric diameter; the average hydrodynamic diameter (dh); and the diameter obtained by external calibration using polystyrene latex standards (dcal). Results between the two NMIs were comparable and coherent with the expected size values of those obtained by other techniques like Scanning Mobility Particle Sizer (SMPS) and Scanning Electron Microscopy (SEM) also involved in this ILC exercise. Where discrepancies are observed, they leave the results compatible within their uncertainties and underpin the challenges in analysing data and reporting results, making AF4 a powerful tool to compare to other measurement techniques.


Assuntos
Difusão Dinâmica da Luz , Fracionamento por Campo e Fluxo , Nanopartículas/análise , Dióxido de Silício/química , Academias e Institutos , Bélgica , França , Tamanho da Partícula , Água/química
9.
Artigo em Russo | MEDLINE | ID: mdl-33307666

RESUMO

The article is dedicated to the 100th anniversary of the Pyatigorsk state research Institute of balneology. It presents the main stages of formation and development, scientific achievements of the Institute and highlights the main activities at the present stage.


Assuntos
Aniversários e Eventos Especiais , Balneologia , Academias e Institutos , História do Século XX
11.
Biomedica ; 40(Supl. 2): 104-115, 2020 10 30.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-33152194

RESUMO

Introduction: The propagation of COVID-19, an infectious disease caused by the novel SARS-CoV-2 coronavirus, has become a pandemic which, along with its rapid dissemination worldwide, has brought about an exponential increase in the amount of research related to the subject to which Latin American researchers have contributed actively. Objective: To conduct a descriptive bibliometric study of the main trends in research on COVID-19 produced in Latin America. Materials and methods: We searched in the Web of Science, Scopus, and Pubmed databases to retrieve the Latin American scientific production on COVID-19. Bibliometric indicators of production, visibility, impact, and collaboration were analyzed to assess the regional participation in studies on the subject. Results: The analysis of 142 documents evidenced an exponential growth of scientific production in the period analyzed, an important level of international collaboration (51.4%) in scientific production, and the leadership of regional institutions (71%) in the research with publications in high-visibility jounals especially in Colombia, Brazil, and México. Conclusions: The results regarding the regional participation in the research on COVID-19 were relevant not only in relation to its quantity and exponential growth during the period analyzed but also in terms of its quality and excellence with a high rate of international collaboration and publications in important scientific journals, which besides their visibility, represent a considerable contribution to the research compared to the other geographical contexts.


Assuntos
Bibliometria , Infecções por Coronavirus , Pandemias , Pneumonia Viral , Academias e Institutos/estatística & dados numéricos , Autoria , Betacoronavirus , Bases de Dados Bibliográficas , Eficiência , Humanos , Internacionalidade , América Latina , Liderança , Publicações Periódicas como Assunto/estatística & dados numéricos
12.
PLoS One ; 15(10): e0241261, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33104715

RESUMO

OBJECTIVE: This study aimed to describe the demographic and clinical characteristics of cancer inpatients with COVID-19 exploring clinical outcomes. METHODS: A retrospective search in the electronic medical records of cancer inpatients admitted to the Brazilian National Cancer Institute from April 30, 2020 to May 26, 2020 granted identification of 181 patients with COVID-19 confirmed by RT-PCR. RESULTS: The mean age was 55.3 years (SD ± 21.1). Comorbidities were present in 110 (60.8%) cases. The most prevalent solid tumors were breast (40 [22.1%]), gastrointestinal (24 [13.3%]), and gynecological (22 [12.2%]). Among hematological malignancies, lymphoma (20 [11%]) and leukemia (10 [5.5%]) predominated. Metastatic disease accounted for 90 (49.7%) cases. In total, 63 (34.8%) had recently received cytotoxic chemotherapy. The most common complications were respiratory failure (70 [38.7%]), septic shock (40 [22.1%]) and acute kidney injury (33 [18.2%]). A total of 60 (33.1%) patients died due to COVID-19 complications. For solid tumors, the COVID-19-specific mortality rate was 37.7% (52 out of 138 patients) and for hematological malignancies, 23.5% (8 out of 34). According to the univariate analysis COVID-19-specific mortality was significantly associated with age over 75 years (P = .002), metastatic cancer (p <0.001), two or more sites of metastases (P < .001), the presence of lung (P < .001) or bone metastases (P = .001), non-curative treatment or best supportive care intent (P < .001), higher C-reactive protein levels (P = .002), admission due to COVID-19 (P = .009), and antibiotics use (P = .02). After multivariate analysis, cases with admission due to symptoms of COVID-19 (P = .027) and with two or more metastatic sites (P < .001) showed a higher risk of COVID-19-specific death. CONCLUSION: This is the first Brazilian cohort of cancer patients with COVID-19. The rates of complications and COVID-19-specific death were significantly high.


Assuntos
Betacoronavirus , Infecções por Coronavirus/epidemiologia , Pacientes Internados/estatística & dados numéricos , Neoplasias/epidemiologia , Pandemias , Pneumonia Viral/epidemiologia , Academias e Institutos/estatística & dados numéricos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Antineoplásicos/efeitos adversos , Antineoplásicos/uso terapêutico , Brasil/epidemiologia , Institutos de Câncer/estatística & dados numéricos , Causas de Morte , Criança , Pré-Escolar , Comorbidade , Diabetes Mellitus/epidemiologia , Suscetibilidade a Doenças , Feminino , Mortalidade Hospitalar , Humanos , Hipertensão/epidemiologia , Hospedeiro Imunocomprometido , Lactente , Masculino , Pessoa de Meia-Idade , Neoplasias/tratamento farmacológico , Estudos Retrospectivos , Adulto Jovem
15.
Zootaxa ; 4790(3): zootaxa.4790.3.1, 2020 Jun 12.
Artigo em Inglês | MEDLINE | ID: mdl-33056693

RESUMO

The type specimens for names of bee taxa in the genera Halictus Latreille, 1804 and Sphecodes Laterille, 1804 of family Halictidae deposited in the Zoological Institute, Russian Academy of Sciences (St. Petersburg) are reviewed. Name-bearing types of 39 species and subspecies are illustrated and detailed information is provided (taxa include 15 described by F. Morawitz; nine by Yu. Pesenko; eight by P. Blüthgen; five by Yu. Astafurova M. Proshchalykin; and two by E. Eversmann). Lectotypes are designated for Halictus flavocallosus Morawitz, 1894, and H. tataricus Blüthgen, 1933.


Assuntos
Himenópteros , Academias e Institutos , Distribuição Animal , Estruturas Animais , Animais , Abelhas , Federação Russa
16.
Mymensingh Med J ; 29(4): 939-944, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-33116099

RESUMO

The Left internal mammary artery (LIMA) is considered the conduit of choice for the surgical treatment (CABG, coronary artery bypass grafting) of Coronary artery disease (CAD) due to its superior long term potency than the other conduits. Sequential anastomosis with the LIMA in CABG increases the number of arterial graft and more completeness the arterial revascularization. To increase the number of arterial graft and improved long term potency, an alternative technique is sequential anastomosis of LIMA to Diagonal (D) & left anterior descending artery (LAD) and LIMA-LIMA "Y" Graft play a vital role in patients with tight proximal lesion. Perioperative data were prospectively collected from all patients with isolated CAD with tight proximal LAD lesion, who underwent off-pump CABG from November 2013 to October 2015 at a single Centre. A total of 321 patients had LIMA to D & LAD sequential and LIMA-LIMA "Y" grafts pattern with severe proximal LAD lesion. The mean age was 54.7±8.4 years, male & female ratio was 29.7:7.5. Left main involvement was in 25% & triple vessel disease was 89% with LVEF 53.6±8.6%. Sequential LIMA to diagonal (side to side) & LAD (end to side) done in all 294 cases and LIMA-LIMA"Y" grafts in 27 cases. Thirty days mortality was 0.935% (3 patients). Postoperative myocardial infarction (MI) occurred in 2 patients (0.623%). Two sequential LIMA graft failed and both the diagonal & LAD bypassed coronary arteries were very narrow, about 1mm in diameter. All the patients underwent postoperative NYHA class evaluation at 3-6 months follow up & found normal and none of the patients suffered for angina. Revascularization with skeletonized sequential LIMA anastomosis to D, LAD & LIMA-LIMA "Y" graft is a safe, feasible with improve overall long-term potency and reproducible alternative in the presence of severe proximal LAD lesion to the complete revascularization of the anterior& lateral myocardial wall. Long term follow-up with coronary angiogram is essential to recommend this technique as standard one.


Assuntos
Doença da Artéria Coronariana , Artéria Torácica Interna , Academias e Institutos , Ponte de Artéria Coronária , Doença da Artéria Coronariana/cirurgia , Feminino , Humanos , Masculino , Artéria Torácica Interna/cirurgia , Pessoa de Meia-Idade
17.
Metas enferm ; 23(8): 73-78, oct. 2020. tab
Artigo em Espanhol | IBECS | ID: ibc-196935

RESUMO

La acreditación como grupo asociado del Grupo de Investigación en Enfermería (GRItaulí) por el Instituto de Investigación e Innovación Parc Taulí es el último paso en un camino iniciado por las enfermeras del Consorcio Corporación Sanitaria Parc Taulí (CCSPT) hace más de 20 años. La investigación desarrollada por enfermeras en el CCSPT de Sabadell tiene una larga trayectoria, entre 1997 y 2020 un total de 228 proyectos de investigación con investigador principal una enfermera han sido aprobados por el Comité de Ética de Investigación con medicamentos del Parc Taulí. En la actualidad el GRItaulí está compuesto por 13 enfermeras y matronas. Desde su acreditación en 2017, el grupo ha obtenido un total de 577.770 euros en financiación de proyectos competitivos y las investigadoras del grupo han publicado siete artículos como primeros firmantes con un factor de impacto acumulado de 8,024. Las estrategias actuales del GRItaulí son: la incentivación de actividades formativas y de divulgación del conocimiento y visibilidad del grupo; la obtención de financiación para conseguir tiempo, elemento cuya escasez se ha identificado como barrera para la investigación; el trabajo en red con otros grupos de investigación de Cataluña y resto de España, y la consolidación de líneas de investigación. Todo ello con el objetivo de promover los cuidados basados en la evidencia y el crecimiento del grupo, posibilitando así la acreditación del GRItaulí en una categoría superior


The accreditation of the Nursing Research Group (GRItaulí) as an associate group by the Parc Taulí Research and Innovation Institute is the last step in the journey started by the nurses of the Consorcio Corporación Sanitaria Parc Taulí (CCSPT) over 20 years ago. The CCSPT nurses in Sabadell have conducted research for a long time, between 1997 and 2020, with 228 research projects in total with a nurse as Primary Investigator which have been approved by the Parc Taulí Ethics Committee for Investigation with Medicinal Products. Currently, the GRItaulí consists of 13 nurses and midwives. Since its accreditation in 2017, the group has obtained 577,770 euros in total as funding for competitive products, and the group researchers have published seven articles as first signatories with a 8,024 cumulative impact factor. The current GRItaulí strategies are: to encourage training and transfer of knowledge and group visibility; to obtain funding in order to achieve time, the lack of which has been identified as a barrier for research; to promote network with other research groups in Catalonia and the rest of Spain, and to strengthen lines of research; all this with the goal to promote evidence-based nursing and group growth, thus enabling the GRItaulí to be accredited in a superior category


Assuntos
Humanos , Pesquisa em Enfermagem Clínica/organização & administração , Academias e Institutos/organização & administração , Pesquisa em Enfermagem Clínica/métodos , Pesquisa em Enfermagem Clínica/tendências , Pesquisa Científica e Desenvolvimento Tecnológico
20.
Vestn Otorinolaringol ; 85(4): 101-105, 2020.
Artigo em Russo | MEDLINE | ID: mdl-32885647

RESUMO

The 75-year history of the creation and organization of the Department of Otorhinolaryngology in the Chelyabinsk Medical Institute (now the South Ural State Medical University) is described in the article. The fascinating path of the formation of the department is setted out consistently from the first days of its creation. The achievements of the department staff are represented at all stages of its organization.


Assuntos
Aniversários e Eventos Especiais , Otolaringologia/educação , Academias e Institutos , História do Século XX , Humanos , Universidades
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