Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 367
Filtrar
1.
Medicine (Baltimore) ; 100(7): e24871, 2021 Feb 19.
Artigo em Inglês | MEDLINE | ID: mdl-33607861

RESUMO

BACKGROUND: Idiopathic short stature (ISS) causes a high economic burden worldwide. As part of a research project that synthesizes economic evidence for Korean medicine treatment of ISS, we describe the methods that will be used for the comprehensive review of articles that analyze health-related economic evaluation for available interventions for ISS using a systematic review methodology. METHODS: Eight electronic English, Korean, and Chinese databases will be searched from their inception until December 2020 to identify studies on the economic evaluation of available interventions on ISS, without language, study design, or publication status restrictions. From the included studies, the effectiveness, utility, and cost data will be collected as the outcome measures by two researchers independently. Descriptive analysis of individual studies will be conducted. If it is judged that the interventions and outcomes of the included studies are sufficiently homogeneous, we will attempt a quantitative synthesis through meta-analysis using Review Manager version 5.4 software (Cochrane, London, UK). RESULTS: This study will summarize the evidence regarding the economic evaluation of available interventions for ISS. CONCLUSIONS: The findings of this review will help clinicians and patients in evidence-based decision-making in clinical settings and help policy makers develop effective policies and distribute resources based on the available evidence.


Assuntos
Análise Custo-Benefício/métodos , Nanismo/economia , Nanismo/terapia , Acupuntura/métodos , Pessoal Administrativo/legislação & jurisprudência , Tomada de Decisão Clínica/ética , Efeitos Psicossociais da Doença , Gerenciamento de Dados , Nanismo/epidemiologia , Feminino , Recursos em Saúde/provisão & distribução , Medicina Herbária/métodos , Hormônio do Crescimento Humano/uso terapêutico , Humanos , Masculino , Ensaios Clínicos Controlados não Aleatórios como Assunto , Ensaios Clínicos Controlados Aleatórios como Assunto , República da Coreia/epidemiologia
2.
Brasília; Fiocruz Brasília;Instituto de Saúde de São Paulo; ago. 11, 2020. 35 p.
Não convencional em Português | LILACS, Coleciona SUS, MOSAICO - Saúde integrativa, PIE | ID: biblio-1118192

RESUMO

A acupuntura se caracteriza pela estimulação de pontos cutâneos específicos por meio do uso de agulhas. A auriculoterapia consiste na estimulação mecânica de pontos específicos do pavilhão auricular com esferas de aço, ouro, prata, plástico, agulhas ou sementes de mostarda. A acupuntura é recomendada para promoção, manutenção e recuperação da saúde, bem como prevenção de agravos e doenças. Além disso, parece propiciar a liberação de neurotransmissores e outras substâncias responsáveis pela promoção da analgesia. A auriculoterapia promove a regulação psíquico orgânica do indivíduo. Ambas as prá ticas foram incorporadas no SUS mediante Portaria nº 971, de 03 de maio de 2006. Qual é a eficácia e a segurança da acupuntura e da auriculoterapia para o tratamento de asma em adultos e/ou idosos? As buscas foram realizadas em sete bases de dados sem restrição de ano de publicação. Os critérios de inclusão foram: revisões sistemáticas em inglês, português e espanhol que avaliaram os efeitos da acupuntura e auriculoterapia no tratamento de asma na população adulta e idosa. A avaliação da qualidade metodológica foi realizada por meio da ferramenta AMSTAR 2, feita por uma pesquisadora e revisada por outra. Nesta revisão rápida, produzida em cinco dias, foram utilizados atalhos metodológicos, de maneira que apenas o processo de seleção foi realizado em duplicidade e de forma independente. De 142 relatos recuperados nas bases de dados, foram incluídas cinco revisões sistemáticas que atenderam aos critérios de elegibilidade. A pergunta de pesquisa incluiu acupuntura e auriculoterapia, o que orientou as buscas de evidências. No entanto, não foram identificados estudos sobre auriculoterapia e a maioria das revisões analisou um tipo específico de acupuntura, denominada farmacopuntura, uma técnica que combina acupuntura com injeção de ervas medicinais. De maneira geral, a farmacopuntura combinada ou não a outros tratamentos, mostrou melhores resultados, em relação a seus comparadores, nos seguin tes desfechos: taxa de resposta e melhora dos sintomas de adultos com asma, melhora da Capacidade Vital Forçada (CVF), do Volume Expiratório Forçado em 1 segundo (VEF1), da relação VEF1/CVF e no Pico de Fluxo Expiratório (PFE). Os resultados sobre acupuntura foram melhores com relação a taxa de melhora dos sintomas de asma e do VEF1. Duas revisões avaliaram a segurança das intervenções, com relatos sobre ocorrência de eventos adversosleves com o uso da farmacopuntura. Esta revisão identificou alguns benefícios da acupuntura e farmacopuntura como tratamento adjuvante em pessoas com asma. No entanto, é necessário interpretar estes resultados com cautela, devido à diversidade de terapias utilizadas nos estudos primários e à qualidade metodológica das revisões sistemáticas, avaliadas como de confiança baixa ou criticamente baixa.


Assuntos
Humanos , Adulto , Pessoa de Meia-Idade , Idoso , Asma/terapia , Terapia por Acupuntura/métodos , Resultado do Tratamento , Acupuntura/métodos
3.
Medicine (Baltimore) ; 99(21): e20343, 2020 May 22.
Artigo em Inglês | MEDLINE | ID: mdl-32481324

RESUMO

INTRODUCTION: The glucagon-like peptide-1 receptor agonists (GLP-1 RAs) class agent has grown rapidly in the last decade due to its effects on lowering HbA1c and weight and the low possibility of hypoglycemia. However, GLP-1 RAs are not devoid of adverse effects among which nausea and vomiting rank first, which reduce adherence to treatment. Accumulated evidences proved that acupuncture can properly treat nausea and vomiting caused by various reasons. The study aims at assessing the safety and effectiveness exhibited by acupuncture treatment for patients with nausea and vomiting induced by GLP-1 RAs. METHODS AND ANALYSIS: Articles that have been identified via electronically searching databases of MEDLINE, Nature, PubMed, the Cochrane Library, WorldSciNet, EMbase, Science Online, AMED, China National Knowledge Infrastructure, the Wanfang Databse and China Biology Medicine Disc and the Chongqing VIP Chinese Science and Technology Periodical Database from their inception of to December 31, 2019 will be incorporated into the systematic review. The review only adopts Chinese and English. It will also pay attention to searching resources of qualified studies, relevant conference proceedings, potential reference list, as well as related system reviews. Two researchers will take charge of completing the selection of research, the extraction of data as well as the assessment of research quality independently. A random- or fixed-effects model will be employed to synthesize data combining the heterogeneity test. The primary outcomes will be nausea and vomiting, seen from the objective and self-reported assessment. Data analysis will be performed via the RevMan 5 software, and GRADE will help to assess the evidence level. The heterogeneity level will determine whether the random-effects model or the fixed-effects model will be used. The 2 categories will adopt risk ratio (RR) or odds ratio (OR) and 95% confidence interval (CI). Continuous variables will adopt the weighted mean difference or standardized mean difference and 95% CI. Meta-analysis will not be conducted if no assessment, like subgroup analysis, is able to explain existing meaningful heterogeneity. The subgroup analysis shall carefully consider each subgroup in certain case. ETHICS AND DISSEMINATION: The systematic review does not involve the evaluation of patients' individual information or patients' right; thus, there is no need to gain the approval from ethical institution. The article will be published in journals reviewed by peers and present at related conference.Registration: Open Science Framework (OSF) Preregistration. 2020, April 8. osf.io/3fgu8.


Assuntos
Acupuntura/métodos , Receptor do Peptídeo Semelhante ao Glucagon 1/agonistas , Hipoglicemiantes/efeitos adversos , Náusea/terapia , Vômito/terapia , Humanos , Náusea/induzido quimicamente , Vômito/induzido quimicamente
4.
Zhongguo Zhen Jiu ; 40(5): 549-52, 2020 May 12.
Artigo em Chinês | MEDLINE | ID: mdl-32394665

RESUMO

Lingshu: Weiqixing (the Chapter 76 of Miraculous Pivot) states the running course and time of the defensive qi circulation, as well as the needling techniques of acupuncture for waiting for qi arrival. However, because of the conflicts on the time system of acupuncture in the record, it is hard to be adopted in clinical practice in the later generations. In comparison of the 28-lunar-mansion time system with the clepsydra time system, it is known that the 28-lunar-mansion time system is much more rational because the clepsydra system is the tool for counting rather than timing. Hence, in compliance with the original meaning recorded in Lingshu: Weiqixing, the method for estimating the circulation of defensive qi is re-collected so as to provide a new approach to the study on the needling techniques of acupuncture for waiting for qi arrival.


Assuntos
Acupuntura/métodos , Fatores de Tempo , Pontos de Acupuntura , Humanos , Qi
5.
Lancet Gastroenterol Hepatol ; 5(3): 316-328, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-31859185

RESUMO

This Review summarises recent pharmacological and upcoming alternative interventions for children with functional abdominal pain disorders (FAPDs). Pharmacological targets include prokinetics and drugs affecting gastric accommodation to treat postprandial distress and nausea. Similarly, anti-inflammatory agents, junctional protein regulators, analgesics, secretagogues, and serotonin antagonists have a therapeutic role for irritable bowel syndrome. Non-pharmacological treatments include peripheral electrical nerve field stimulation to the external ear, gastric electrical stimulation, dietary interventions such as low fructose and fibre based diets, and nutraceuticals, which include probiotics, prebiotics, and synbiotics. Newer psychological advances such as exposure-based cognitive behavioural therapy, acceptance and commitment therapy, and mindfulness meditation are being investigated for paediatric functional pain. Lastly, alternative therapies such as acupuncture, moxibustion, yoga, and spinal manipulation are also gaining popularity in the treatment of FAPDs.


Assuntos
Dor Abdominal/tratamento farmacológico , Síndrome do Intestino Irritável/tratamento farmacológico , Náusea/tratamento farmacológico , Período Pós-Prandial/efeitos dos fármacos , Dor Abdominal/fisiopatologia , Dor Abdominal/terapia , Terapia de Aceitação e Compromisso/métodos , Acupuntura/métodos , Adolescente , Analgésicos/uso terapêutico , Anti-Inflamatórios/uso terapêutico , Criança , Pré-Escolar , Terapia Cognitivo-Comportamental/métodos , Dietoterapia/métodos , Suplementos Nutricionais/estatística & dados numéricos , Estimulação Elétrica/métodos , Feminino , Humanos , Masculino , Manipulação da Coluna/métodos , Atenção Plena/métodos , Moxibustão/métodos , Prebióticos/estatística & dados numéricos , Probióticos/uso terapêutico , Angústia Psicológica , Secretagogos/uso terapêutico , Antagonistas da Serotonina/uso terapêutico , Simbióticos/administração & dosagem , Resultado do Tratamento , Ioga , Adulto Jovem
6.
PLoS One ; 14(12): e0226304, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31826009

RESUMO

BACKGROUND: Recently, porous acupuncture (PA), which is anodized to increase its surface area for higher stimulation intensity, was developed and showed significantly improved therapeutic effects with more comfort as compared with original acupuncture (OA) in vivo. However, the impact of PA on the change of local blood flow as well as its efficacy and acceptability has not yet been confirmed in a clinical trial. In a randomized, controlled crossover clinical trial, we investigated the effects of PA on the change in local blood flow using laser Doppler perfusion imaging and considered the sensation of pain intensity and discomfort severity using a visual analogue scale (VAS) to explore its physiological impact and the possibility of PA in clinical use. METHODS: Twenty-one healthy participants were randomly treated with PA or OA on one side of Zusanli (ST36) and each participant served as his or her own control. Baseline local blood flow and galvanic skin response (GSR) were obtained for 5 min and acupuncture interventions were subsequently performed. Next, local blood flow and GSR were subsequently obtained for 10 min after insertion, 10 min after manipulation, and 5 min after the withdrawal of acupuncture. At the end of the experiment, participants were asked to indicate the sensation of pain intensity at each session of insertion, retention, manipulation, and withdrawal as well as the overall pain intensity and discomfort severity. RESULTS: PA significantly increased the local blood flow as compared with OA and there was no significant difference in GSR between patients treated with PA versus OA in each phase of insertion and manipulation. No significant difference in pain intensity or discomfort severity was found during manipulation, retention, or withdrawal of acupuncture. CONCLUSIONS: These results indicate that PA increases local blood flow, which can be closely related to the observed enhanced performance, without any associated discomfort or pain, suggesting its applicability in clinical practice.


Assuntos
Acupuntura/métodos , Nanoporos , Pele/diagnóstico por imagem , Adolescente , Adulto , Feminino , Resposta Galvânica da Pele , Voluntários Saudáveis , Humanos , Masculino , Pessoa de Meia-Idade , Dor/patologia , Medição da Dor , Imagem de Perfusão/métodos , Fluxo Sanguíneo Regional , Índice de Gravidade de Doença , Pele/irrigação sanguínea , Adulto Jovem
7.
J Low Genit Tract Dis ; 23(4): 279-286, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31592976

RESUMO

OBJECTIVE: The aim of the study was to assess the feasibility and acceptability of acupuncture's augmentation of lidocaine therapy in the treatment of provoked localized vulvodynia (PLV). MATERIALS AND METHODS: For 12 weeks, women with moderate to severe PLV were randomized to either 18 sessions of traditional acupuncture (TA) or non-TA (NTA). All participants applied lidocaine 5% cream 4 times daily to the vestibule. Feasibility was assessed by recruitment, enrollment, assessment completion, and blinding. Acceptability was assessed by study visit attendance and satisfaction. The primary outcome was change in tampon test scores from baseline to week 12 and follow-up at week 24. RESULTS: Nineteen women enrolled and 14 completed the study. Five withdrew because of lidocaine reaction (n = 2), inability to insert tampon (n = 1), starting a new medication (n = 1), or change in vulvar diagnosis (n = 1). Participants in both groups reported pain reduction for 12 weeks. There was no statistically significant difference between groups. Women in the TA group (n = 7) experienced less pain from baseline to 12 weeks (mean difference [MD] = 42.4 ± 19.4 and MD = 35.7 ± 17.8 at week 24). In the non-TA group (n = 7), women experienced a within-group MD of 28.7 ± 28.5 at 12 weeks and an MD of 36.7 ± 17.7. CONCLUSIONS: In this early-phase research, acupuncture augmentation of lidocaine was acceptable. The study procedures, with modifications, may be feasible for future investigation. Both acupuncture techniques showed a favorable effect; however, the contribution to pain relief is undetermined.


Assuntos
Acupuntura/métodos , Anestésicos Locais/administração & dosagem , Lidocaína/administração & dosagem , Vulvodinia/terapia , Adolescente , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Aceitação pelo Paciente de Cuidados de Saúde , Resultado do Tratamento , Adulto Jovem
8.
Integr Cancer Ther ; 18: 1534735419866910, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31387468

RESUMO

Background: Breast cancer-related lymphedema (BCRL) is hard to control. Management may include lymphatic drainage, skin care, bandaging, or even surgery. Since acupuncture has been proven to affect the neurophysiology and neuroendocrine systems, it has the potential to control BCRL. Aim: To evaluate the effect of acupuncture in BCRL in randomized controlled trials. Design: A literature search was performed, following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement and without language restrictions. Data Sources: Five databases were searched from inception tthrough September 2018. Only studies that fulfilled the eligibility criteria of evaluating the effect of acupuncture on lymphedema in breast cancer were included. The methodological quality of these trials was assessed using the Cochrane criteria, and meta-analysis software (RevMan 5.3) was used for analysis. Results: We examined 178 breast cancer patients from 6 trials. All included randomized controlled trials had medium to high quality, based on the modified Jadad scale. The systematic review showed that acupuncture is safe and has a trend to improve symptoms, but trials did not consistently measure outcomes. The meta-analysis showed that acupuncture produced no significant improvement in the extent of lymphedema as compared with the control intervention (-1.90; 95% confidence interval = -5.39 to 1.59, P = .29). None of the studies reported severe adverse events. Conclusions: Acupuncture is safe and has a trend to improve the lymphedema related to breast cancer, yet it did not significantly change arm circumference in BCRL. Future studies should include both subjective and objective measurements and large-scale studies are warranted.


Assuntos
Linfedema Relacionado a Câncer de Mama/terapia , Neoplasias da Mama/terapia , Acupuntura/métodos , Terapia por Acupuntura/métodos , Feminino , Humanos , Qualidade de Vida , Ensaios Clínicos Controlados Aleatórios como Assunto
9.
Brain Behav ; 9(9): e01370, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-31359627

RESUMO

BACKGROUND: Acupuncture at Zusanli (ST36) is often used to facilitate motor recovery after stroke. However, the effect of acupuncture at ST36 on motor cortical excitation and inhibition remains unclear. This study aimed to explore the effect of acupuncture at ST36 on motor cortical excitation and inhibition. METHODS: Twenty healthy volunteers were recruited to receive acupuncture treatment. We selected the acupoint ST36 and its respective sham point as the experimental acupoint. Transcranial magnetic stimulation (TMS) was used to measure motor-evoked potentials (MEP) at 7 time points-before acupuncture (Pre), acupuncture (T0), 4 and 8 min after acupuncture (T4; T8), needle removal (T12), 4 and 8 min after needle removal (T16; T20). Simultaneously, paired TMS (pTMS) was employed to measure short- and long-interval intracortical inhibition (SICI [short latency intracortical inhibition]; LICI [long latency intracortical inhibition]), respectively, at three time points-before acupuncture (Pre), acupuncture (T0), needle removal (T12). After removing the acupuncture needle, all subjects were asked to quantify their Deqi sensation using a Gas table. RESULTS: The average Deqi sensation score of all subjects during acupuncture at ST36 was higher than that observed at the sham point. With acupuncture at ST36, the MEP amplitude was higher at three time points (T0, T4, T8) than at Pre, although the MEP amplitude tended toward Pre after needle removal. The MEP amplitude was also higher at the same time points (T0, T4, T8) than at the sham point. Furthermore, the Deqi sensation score was correlated with MEP amplitude. With acupuncture at ST36, SICI and LICI at T0 were higher than those at Pre, and SICI and LICI at T0 were higher than those at the sham point. CONCLUSION: Acupuncture at ST36 increased motor cortical excitation and had an effect on the remaining needle phase. Deqi sensation was correlated with MEP amplitude. Acupuncture at ST36 also decreased motor cortical inhibition.


Assuntos
Pontos de Acupuntura , Acupuntura/métodos , Potencial Evocado Motor/fisiologia , Córtex Motor/fisiologia , Inibição Neural/fisiologia , Terapia por Acupuntura , Adolescente , Adulto , Eletromiografia , Feminino , Voluntários Saudáveis , Humanos , Masculino , Músculo Esquelético , Acidente Vascular Cerebral/terapia , Estimulação Magnética Transcraniana , Adulto Jovem
10.
Integr Cancer Ther ; 18: 1534735419848494, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31046489

RESUMO

BACKGROUND: Acupuncture is a recognized integrative modality for managing hot flashes. However, data regarding predictors for response to acupuncture in cancer patients experiencing hot flashes are limited. We explored associations between patient characteristics, including traditional Chinese medicine (TCM) diagnosis, and treatment response among cancer patients who received acupuncture for management of hot flashes. METHODS: We reviewed acupuncture records of cancer outpatients with the primary reason for referral listed as hot flashes who were treated from March 2016 to April 2018. Treatment response was assessed using the hot flashes score within a modified Edmonton Symptom Assessment Scale (0-10 scale) administered immediately before and after each acupuncture treatment. Correlations between TCM diagnosis, individual patient characteristics, and treatment response were analyzed. RESULTS: The final analysis included 558 acupuncture records (151 patients). The majority of patients were female (90%), and 66% had breast cancer. The median treatment response was a 25% reduction in the hot flashes score. The most frequent TCM diagnosis was qi stagnation (80%) followed by blood stagnation (57%). Older age ( P = .018), patient self-reported anxiety level ( P = .056), and presence of damp accumulation in TCM diagnosis ( P = .047) were correlated with greater hot flashes score reduction. CONCLUSIONS: TCM diagnosis and other patient characteristics were predictors of treatment response to acupuncture for hot flashes in cancer patients. Future research is needed to further explore predictors that could help tailor acupuncture treatments for these patients.


Assuntos
Fogachos/etiologia , Fogachos/terapia , Neoplasias/complicações , Acupuntura/métodos , Terapia por Acupuntura/métodos , Feminino , Humanos , Masculino , Medicina Tradicional Chinesa/métodos , Pessoa de Meia-Idade , Estudos Retrospectivos
11.
Complement Ther Med ; 44: 166-173, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31126551

RESUMO

OBJECTIVES: The purpose of this research was to investigate the effect of Urtica dioica in comparison with placebo, acupuncture and combined therapy on hot flashes and quality of life in postmenopausal women. METHODS: In a double-blinded randomized controlled trial, patients were treated for 7 weeks then followed up 4 weeks. Seventy-two postmenopausal women who reported at least 20 hot flashes attacks per week were randomly allocated into one of the 4 groups of Urtica dioica 450 mg/day and acupuncture 11 sessions (A), acupuncture and placebo (B), sham acupuncture and Urtica dioica (C), and sham acupuncture and placebo (D). The primary outcomes were the change in hot flashes score from baseline to the end of treatment and follow up; and the change in the quality of life (MENQOL) from baseline to the end of treatment. Secondary outcomes included changes in FSH, LH, and ESTRADIOL levels from baseline to the end of treatment. The trial was conducted from October 2017 to July 2018 in Acupuncture clinic of a teaching hospital in Iran. RESULTS: A total of 72 women 45-60 years old were enrolled, and 68 were included in the analyses. The median (IQR) hot flashes score decreased in the A group by 20.2 (31.7) and 21.1 (25.1), B group by 19 (18) and 17.3 (27), C group by 14.6 (25.4) and 20.8 (13), and D group by 1.6 (11.6) and 1 (13.3) at the end of treatment and follow up (P < 0.0001, P < 0.0001); no significant difference between A, B and C groups. The mean (SD) of MENQOL score decreased in the A group by 42.6 (21.1), B group by 40.7 (29.8), C group by 37.8 (26.8) and D group by 9.8 (14.3) at the end of treatment (P = 0.001); no significant difference between A, B and C groups. CONCLUSIONS: Urtica dioica can decrease menopausal hot flashes and increase the quality of life of postmenopausal women better than placebo-sham control but same as acupuncture. The combination of Urtica dioica and acupuncture did not add to the effects of those therapies.


Assuntos
Fogachos/tratamento farmacológico , Fogachos/terapia , Menopausa/efeitos dos fármacos , Preparações de Plantas/uso terapêutico , Urtica dioica/química , Acupuntura/métodos , Terapia por Acupuntura/métodos , Método Duplo-Cego , Feminino , Humanos , Irã (Geográfico) , Pessoa de Meia-Idade , Pós-Menopausa/efeitos dos fármacos , Qualidade de Vida , Índice de Gravidade de Doença , Resultado do Tratamento
12.
Complement Ther Med ; 44: 182-188, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31126554

RESUMO

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common and heterogeneous endocrine disorder in reproductive-age women. Tung's acupuncture, a Traditional Chinese Medicine (TCM) treatment, is widely used for PCOS in East Asia, but evidence on its efficacy is rare. The aim of this RCT study was to examine whether the Tung's acupuncture could be a complementary treatment method for PCOS. METHODS: A total of 60 PCOS patients were randomly assigned to a Tung's acupuncture group (n = 30) or a cyproterone acetate/ethinylestradiol (CPA/EE) group (n = 30). Each participant received treatments for 12 weeks to assess the short-term treatment efficacy and then followed up for another 12 weeks to assess the long-term treatment efficacy. The primary outcome examined was change in the ratio of luteinizing hormone (LH) to follicle-stimulating hormone (FSH); the secondary outcomes examined were changes in body mass index (BMI), LH, FSH, total testosterone (TT), ovarian volume, polycystic ovary number and menstrual frequency. RESULTS: Both groups showed significant reductions in the LH/FSH ratio, LH and TT after 12-week treatment (p < 0.001) and 12-week follow-up (p < 0.05). No significant differences existed between the two groups (p > 0.05). Both groups showed significant improvement in BMI, menstrual frequency and polycystic ovary number after 12-week treatment (p < 0.05). CONCLUSION: Compared with CPA/EE, Tung's acupuncture showed no better improvement on LH/FSH ratio for PCOS although it could reduce the ratio. Tung's acupuncture might have some effect on long-term weight control and menstruation frequency. Further studies addressing this study's limitations are recommended.


Assuntos
Hormônios Esteroides Gonadais/metabolismo , Síndrome do Ovário Policístico/terapia , Acupuntura/métodos , Terapia por Acupuntura/métodos , Adulto , Índice de Massa Corporal , Acetato de Ciproterona/uso terapêutico , Combinação de Medicamentos , Etinilestradiol/uso terapêutico , Feminino , Humanos , Síndrome do Ovário Policístico/tratamento farmacológico
13.
Biomed Res Int ; 2019: 6597503, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31016194

RESUMO

Background: Previous studies have demonstrated that acupuncture was an effective alternative for treating major depressive disorders. However, the use of acupuncture for the treatment of postpartum depression remains controversial. This review summarizes the most significant studies in the area of acupuncture treatment for postpartum depression and provides a detailed overview of the efficacy of acupuncture for the treatment of postpartum depression. Methods: We undertook a systematic review of publicly available electronic databases to identify studies that evaluated acupuncture for the treatment of postpartum depression. Our meta-analysis selected randomized controlled trials (RCTs) and quasi-RCTs that reported on the treatment effect of acupuncture on postpartum depression. Results: Eight prospective trials reporting data on postpartum depression were included in our meta-analysis. The results demonstrated that acupuncture treatment could significantly reduce HAMD scores (SMD: -1.08; 95%CI: -2.11 to -0.05; P=0.040). However, with regard to EPDS, clinical response, and serum estradiol levels, pooled analysis suggested no beneficial effects of acupuncture for postpartum women in EPDS (RR: 1.23; 95%CI: 0.90 to 1.67; P=0.195); clinical response (RR: 1.00; 95%CI: 0.89 to 1.12; P=0.969); and the levels of serum estradiol (SMD: 1.96; 95%CI: -0.01 to 3.93; P=0.051). Limitations: First, there was relatively high heterogeneity among the studies, except for clinical response. In order to identify the sources of heterogeneity, we divided the studies into subgroups by way of controls. However, heterogeneity still existed, which suggested that it arose from participants rather than controls. Second, the sample size of the studies was small, causing the power of summary results to be low. This may result in over- or underestimating the interpretation of the results. Third, our analysis used pooled data, which restricted us from performing a more detailed analysis. Conclusions: Our meta-analysis suggested that acupuncture treatment may reduce HAMD scores, while no significant effects on EPDS, clinical response, and serum estradiol levels were observed.


Assuntos
Depressão Pós-Parto/terapia , Acupuntura/métodos , Terapia por Acupuntura/métodos , Transtorno Depressivo Maior/terapia , Feminino , Humanos , Período Pós-Parto/fisiologia , Estudos Prospectivos , Ensaios Clínicos Controlados Aleatórios como Assunto
14.
Integr Cancer Ther ; 18: 1534735419836501, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30905173

RESUMO

PURPOSE: Chemotherapy-induced peripheral neuropathy is a complex side effect with few available treatment options. The aim of the study was to test the effectiveness of an 8-week course of acupuncture in the management of chemotherapy-induced peripheral neuropathy in cancer patients who were receiving or had received neurotoxic chemotherapy. METHODS: Randomized assessor-blinded controlled trial with 2 arms; one arm received acupuncture twice weekly for 8 weeks, while the other arm was a wait-list control group receiving only standard care. Primary outcome was pain intensity and interference over the past week using the Brief Pain Inventory at the end of the intervention. Secondary outcomes included clinical assessment (CTCAE [Common Toxicity Criteria for Adverse Events] grading and Total Neuropathy Score-Clinical Version) and nerve conduction studies; and patient-reported outcome measures (Functional Assessment of Cancer Therapy-Gynecologic Oncology Group-Neurotoxicity Quality of Life scale and Symptom Distress Scale) assessed at baseline, end of treatment (8 weeks), week 14, and week 20 from the beginning of treatment. RESULTS: Eighty-seven patients were randomized to the experimental arm (n = 44) and to the standard care wait-list control arm (n = 43). Significant changes at 8 weeks were detected in relation to primary outcome (pain), the clinical neurological assessment, quality of life domains, and symptom distress (all P < .05). Improvements in pain interference, neurotoxicity-related symptoms, and functional aspects of quality of life were sustained in the 14-week assessment ( P < .05), as were physical and functional well-being at the 20-week assessment ( P < .05). CONCLUSIONS: Acupuncture is an effective intervention for treating chemotherapy-induced peripheral neuropathy and improving patients' quality of life and experience with neurotoxicity-related symptoms with longer term effects evident.


Assuntos
Antineoplásicos/efeitos adversos , Doenças do Sistema Nervoso Periférico/induzido quimicamente , Doenças do Sistema Nervoso Periférico/tratamento farmacológico , Acupuntura/métodos , Terapia por Acupuntura/métodos , Antineoplásicos/uso terapêutico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias/tratamento farmacológico , Dor/induzido quimicamente , Dor/tratamento farmacológico , Qualidade de Vida , Inquéritos e Questionários
15.
Holist Nurs Pract ; 33(2): 90-94, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30747777

RESUMO

Holistic nursing practices holism and holistic modalities to create a healing space and optimize the healing process. Holistic nurses employ a complementary and integrative focus in their work and help patients access their greatest healing potential. This article supports that nursing professionals embrace acupuncture and alternative therapy as a great gift that inspire them to extend their already extraordinary healing power. An overview of the history of Traditional Chinese Medicine and the development and milestones of acupuncture and moxibustion in past dynasties is presented. In particular, the development of Traditional Chinese Medicine and acupuncture in the last 20 years, as well as how social and economic conditions have impacted their expansion, is discussed.


Assuntos
Enfermagem Holística/métodos , Medicina Tradicional Chinesa/história , Acupuntura/história , Acupuntura/métodos , História do Século XV , História do Século XVI , História do Século XVII , História do Século XVIII , História do Século XIX , História do Século XX , História Antiga , História Medieval , Medicina Tradicional Chinesa/métodos
16.
Medicine (Baltimore) ; 98(1): e13934, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30608423

RESUMO

BACKGROUND: Epididymitis is a common disease in non-specific infections of the male reproductive system. According to the clinical incidence of acute epididymitis and chronic epididymitis, which is more common in chronic epididymitis. There are many clinical trials confirmed that acupuncture treatment can relieve pain and improve symptoms of epididymitis to some extent. In this systematic review, we aim to evaluate the effectiveness and safety of acupuncture for epididymitis. METHODS AND ANALYSIS: We will search for PubMed, Cochrane Library, AMED, EMbase, WorldSciNet; Nature, Science online and China Journal Full-text Database (CNKI), China Biomedical Literature CD-ROM Database (CBM), and related randomized controlled trials included in the China Resources Database. The time is limited from the construction of the library to November 2018. We will use the criteria provided by Cochrane 5.1.0 for quality assessment and risk assessment of the included studies, and use the Revman 5.3 and Stata13.0 software for meta-analysis of the effectiveness, recurrence rate, and symptom scores of epididymitis. ETHICS AND DISSEMINATION: This systematic review will evaluate the efficacy and safety of acupuncture for epididymitis. Because all of the data used in this systematic review and meta-analysis has been published, this review does not require ethical approval. Furthermore, all data will be analyzed anonymously during the review process trial. REGISTRATION NUMBER: PROSPERO CRD42018111348.


Assuntos
Terapia por Acupuntura/métodos , Acupuntura/métodos , Epididimite/terapia , Acupuntura/estatística & dados numéricos , Terapia por Acupuntura/efeitos adversos , Bases de Dados Factuais , Epididimite/epidemiologia , Humanos , Masculino , Manejo da Dor/métodos , Ensaios Clínicos Controlados Aleatórios como Assunto , Resultado do Tratamento
17.
Medicine (Baltimore) ; 97(50): e13655, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30558062

RESUMO

This study aimed to explore the feasible gender differences and similarities in cerebral activity response to the acupuncture at local acupoints around knee.Fifteen male and 15 female healthy adults were recruited and included in this study. Functional magnetic resonance imaging (fMRI) was applied to measure cerebral activity response to acupuncture at Liangqiu (ST34), Xuehai (SP-10), Neixiyan (EX-LE4), and Dubi (ST-35).Acupuncture activated the postcentral gyrus, precuneus, temporal, posterior lobe, and occipital lobe in both males and females. When compared with females, males showed brain activation in the right middle frontal gyrus, inferior frontal gyrus, right precuneus, right superior parietal lobule, left cerebellum anterior lobe; and brain deactivation in the right frontal. When compared with males, females were observed brain activation in the right frontal lobe, right parietal lobe, and right middle temporal gyrus; and brain deactivation in the left and right medial frontal gyrus.The results of this study demonstrated that the neural effects of local acupoints around knee might be different between male and female subjects. Further clinical trials should take this gender effect into account in their design of studies.


Assuntos
Terapia por Acupuntura/métodos , Acupuntura/métodos , Encéfalo/diagnóstico por imagem , Joelho/inervação , Pontos de Acupuntura , Terapia por Acupuntura/efeitos adversos , Adulto , Encéfalo/anatomia & histologia , Encéfalo/fisiologia , Feminino , Humanos , Joelho/patologia , Joelho/fisiopatologia , Imagem por Ressonância Magnética/métodos , Masculino , Ensaios Clínicos Controlados não Aleatórios como Assunto/métodos , Dor , Fatores Sexuais
18.
Sci Rep ; 8(1): 17966, 2018 12 19.
Artigo em Inglês | MEDLINE | ID: mdl-30568247

RESUMO

The aim of this study was to evaluate the tips and the surface conditions of two types of needles with different quality and their possible alterations after performing different needling on human beings. A total of 160 needles from AguPunt brand were examined. Surface conditions (lumps and scratches) and tip of the needles after needling procedures in humans were tested using a JEOL JSM-6360LV microscopy device. Additionally, a group of physiotherapists assessed the use of both types of needles in clinical practice using a self-reported questionnaire. Both types of needles, after performing different needling on human beings, kept the needle tips well preserved although the dry needle (Type B) suffered very little deformation even touching the bone of the scapula 10 times versus acupuncture needle (Type A), which were deformed slightly. The surface conditions revealed irregularities and scratches in both types of needles but the tips of Type A suffered more damage after different procedures (Odds ratio = 0.04,95% CI:0.01-0.13, p < 0.001). The cellular tissue adhered to the surface was similar in both types of needles and the questionnaire about clinical practice of both types of needles showed that Type B seemed easier than Type A when the physical therapist penetrated the skin and when the needle went out the skin.


Assuntos
Acupuntura , Microscopia Eletrônica de Varredura , Agulhas , Acupuntura/métodos , Terapia por Acupuntura , Adolescente , Adulto , Feminino , Humanos , Masculino , Microscopia Eletrônica de Varredura/instrumentação , Microscopia Eletrônica de Varredura/métodos , Pele , Fluxo de Trabalho , Adulto Jovem
19.
CNS Neurosci Ther ; 24(12): 1264-1274, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-30278105

RESUMO

AIMS: Acupuncture has been reported to affect vascular dementia through a variety of molecular mechanisms. An isobaric tag for relative and absolute quantification (iTRAQ) with high-resolution liquid chromatography-tandem mass spectrometry (LC-MS/MS) analyses makes it possible to attain a global profile of proteins. Hence, we used an iTRAQ-LC-MS/MS strategy to unravel the underlying mechanism of acupuncture. METHODS: Wistar rats were subjected to vascular dementia with bilateral common carotid occlusion. Acupuncture was intervened for 2 weeks at 3 days after surgery. The Morris water maze was used to assess the cognitive function. Proteins were screened by quantitative proteomics and analyzed by bioinformatic analysis. Four differentially expressed proteins (DEPs) were validated by western blot. The reactive oxygen species (ROS) production, neuron cell loss, and long-term potentiation (LTP) were determined after western blot. RESULTS: Acupuncture at proper acupoints significantly improved cognitive function. A total of 31 proteins were considered DEPs. Gene ontology (GO) analysis showed that most of the DEPs were related to oxidative stress, apoptosis, and synaptic function, which were regarded as the major cellular processes related to acupuncture effect. Western blot results confirm the credibility of iTRAQ results. Acupuncture could decrease ROS production, increase neural cell survival, and improve LTP, which verified the three major cellular processes. CONCLUSION: Acupuncture may serve as a promising clinical candidate for the treatment of vascular dementia via regulating oxidative stress, apoptosis, or synaptic functions.


Assuntos
Acupuntura/métodos , Transtornos Cognitivos/etiologia , Transtornos Cognitivos/terapia , Demência Vascular/complicações , Regulação da Expressão Gênica/fisiologia , Pontos de Acupuntura , Animais , Doenças das Artérias Carótidas/complicações , Cromatografia por Troca Iônica , Biologia Computacional , Demência Vascular/etiologia , Modelos Animais de Doenças , Estimulação Elétrica , Potenciação de Longa Duração/fisiologia , Masculino , Aprendizagem em Labirinto/fisiologia , Microinjeções , Proteômica/métodos , RNA Interferente Pequeno/administração & dosagem , Ratos , Ratos Wistar , Subunidade beta da Proteína Ligante de Cálcio S100/genética , Subunidade beta da Proteína Ligante de Cálcio S100/metabolismo , Espectrometria de Massas em Tandem
20.
J Cancer Res Ther ; 14(Supplement): S600-S608, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30249875

RESUMO

Objective: To critically assess the effectiveness and safety of acupuncture for treating hot flashes (HFs) among breast cancer (BC) patients, and to get much more highly compelling evidence then to guide clinical practice. Methods: Comprehensive systematic literature searches were carried out for identifying randomized controlled trials and observational studies (OSs) published before January 2015. The meta-analysis (MA) was performed by Review Manager 5 software if data could be merged routinely, if not descriptions would be given. Results: A total of 18 studies were eligible ultimately. With respect to HFs frequency, the MA during treatment showed a significant difference (MD = -1.78, 95% confidence intervals [95% CIs]: -3.42--0.14), but no statistical differences were observed when posttreatment or follow-up period. While electroacupuncture versus applied relaxation, they both helped to promote HFs markedly but did not reveal statistically significance between them. Referring to Kupperman's index, all the treatment brought out great assistance when compared with baseline conditions, and there was significant difference between real acupuncture sham acupuncture (posttreatment: MD = -4.40, 95% CI: -6.77--2.03; follow-up: MD = -4.30, 95% CI: -6.52--2.08). In terms of OS, 7 prospective single arm studies focused on exploring the efficacy of traditional acupuncture, and all revealed moderate or great benefit for BC patients suffering from HFs. Conclusions: Acupuncture still appeared to be an efficacious therapeutic strategy, especially for the less/no side effects. Because of its widespread acceptance and encouraging effectiveness for improving HFs, much more high-quality studies are in need urgently.


Assuntos
Acupuntura/métodos , Neoplasias da Mama/terapia , Fogachos/terapia , Neoplasias da Mama/complicações , Neoplasias da Mama/patologia , Feminino , Fogachos/complicações , Fogachos/patologia , Humanos , Estudos Prospectivos , Qualidade de Vida , Ensaios Clínicos Controlados Aleatórios como Assunto
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...