Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 2.522
Filtrar
1.
Nutrients ; 15(1)2023 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-36615870

RESUMO

We performed this study to investigate the association between sugar-sweetened beverage (SSB) consumption and male pattern hair loss (MPHL) in young men. We conducted this cross-sectional study from January to April 2022 in mainland China. Young people aged 18-45 years (n = 1951) were recruited from 31 provinces in China. We used a self-reported online survey for data collection. We explored the associations between the amount/frequency of SSB consumption and MPHL by using a binary logistic regression model, with adjustments for sociodemographic, hair status, dietary intake, lifestyle, and psychological factors. Among the 1028 participants (27.8 ± 7.2 years) in the final analysis, we found that high SSB consumption is associated with a higher risk of MPHL. We recommend more support to decrease SSB consumption among young people to minimize negative health outcomes.


Assuntos
Bebidas Adoçadas com Açúcar , Humanos , Masculino , Adolescente , Bebidas Adoçadas com Açúcar/efeitos adversos , Estudos Transversais , Inquéritos e Questionários , Estilo de Vida , Alopecia/epidemiologia , Alopecia/etiologia , Bebidas
2.
J Drugs Dermatol ; 22(1): 29-34, 2023 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-36607760

RESUMO

The treatment of primary scarring alopecias is challenging and patients may be susceptible to koebnerization. This predisposes cicatricial alopecia patients to worsening of their disease following procedural treatments or interventions. Research and recommendations surrounding the risk for koebnerization within scarring alopecias is extremely limited. Using a comprehensive literature review, we summarized the risks of procedures in potentially koebnerizing alopecias. We evaluated the risk not only with procedural treatments, but also with common elective cosmetic procedures and potentially trauma-inducing hairstyling techniques. Although additional studies are needed to better elucidate the risks of procedural treatments within primary scarring alopecia, we believe this review of the current evidence and expert insight will benefit healthcare providers and patients alike to help guide treatments in this challenging patient population. J Drugs Dermatol. 2023;22(1):29-34. doi:10.36849/JDD.6849.


Assuntos
Alopecia , Cicatriz , Humanos , Cicatriz/diagnóstico , Cicatriz/etiologia , Cicatriz/terapia , Alopecia/diagnóstico , Alopecia/etiologia , Alopecia/tratamento farmacológico , Pessoal de Saúde
3.
J Drugs Dermatol ; 21(12): 1316-1321, 2022 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-36468968

RESUMO

BACKGROUND: Social media platforms continue to grow in popularity and have become common sources of medical information and education for patients struggling with hair loss. OBJECTIVE: We sought to determine the characteristics of popular hair loss related content on Instagram and TikTok. METHODS: The top 9 most popular posts within 10 hair loss related hashtags on Instagram and TikTok were analyzed. Quantitative and qualitative analysis was used to evaluate posts from December 2020. The characteristic of the author, content category, and number of likes were analyzed for each post. RESULTS: Of 90 posts analyzed within Instagram, non-medical professional influencers created 66%, hair and wig companies created 29%, and medical professionals created 4%. Of 100 posts analyzed within TikTok, influencers created 38%, patients created 38%, hair and wig companies created 14%, and medical professionals created 10%. None of the top posts was created by board-certified dermatologists. LIMITATIONS: This study was limited by the extent of data that can be collected from Instagram and TikTok. CONCLUSIONS: A majority of the content promoted hair care products, services, or treatments not substantiated by evidence-based medicine. Instagram and TikTok provide new opportunities for dermatologists to educate the general population on alopecia while simultaneously correcting misinformation. J Drugs Dermatol. 2022;21(12):1316-1321. doi:10.36849/JDD.6707.


Assuntos
Mídias Sociais , Humanos , Emoções , Alopecia/diagnóstico , Alopecia/epidemiologia , Alopecia/etiologia
6.
J Craniofac Surg ; 33(8): 2450-2454, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36409869

RESUMO

ABSTRACT: Scalp defects of various etiologies require distinct reconstruction strategies. Therefore, the authors divided scalp defects into the following categories: scar alopecia, open scalp wound, benign or low-grade malignant tumor, and high-grade malignancy. The authors reviewed the experience with scalp reconstruction of a single center to determine the factors that affect the reconstructive choices.Patients who underwent scalp reconstruction between 2008 and 2020 were retrospectively reviewed. Reconstruction methods were classified according to the etiology of the defect and were compared for each etiology. Accordingly, a reconstruction algorithm for scalp defects was proposed.A total of 180 patients were included in this study, and the reconstruction methods demonstrated significant differences according to etiology (P < 0.05). For scar alopecia and open scalp wounds, reconstruction methods such as direct repair, local flap transfer, and tissue expander placement were used depending on the defect size. Patients with benign or low-grade malignancies mainly underwent reconstruction with local flaps or skin grafts and tissue expanders for covering the defects. Patients with high-grade malignancies underwent reconstruction with free flaps if they were scheduled for preoperative or postoperative radiation therapy.Various factors, suchas the etiology, size, location, and depthofthe defect, should be considered in scalp reconstruction. The defect etiology is an important factor that determines the reconstructive goal. Our algorithm is based on the etiology of defects and is intended to aid physicians in choosing the appropriate treatment for various scalp defects.


Assuntos
Retalhos de Tecido Biológico , Neoplasias , Humanos , Couro Cabeludo/lesões , Estudos Retrospectivos , Cicatriz/cirurgia , Retalhos de Tecido Biológico/cirurgia , Neoplasias/patologia , Neoplasias/cirurgia , Alopecia/etiologia , Alopecia/cirurgia
7.
8.
JAAPA ; 35(12): 36-38, 2022 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-36412939

RESUMO

ABSTRACT: This article describes a 23-year-old woman with bruising, hair loss, and stretch marks, which was found to be due to Cushing syndrome. Because of its nonspecific symptoms, this disease of hypercortisolism can be mistaken for other conditions.


Assuntos
Síndrome de Cushing , Estrias de Distensão , Feminino , Humanos , Adulto Jovem , Adulto , Alopecia/etiologia , Síndrome de Cushing/diagnóstico
9.
West Afr J Med ; 39(10): 1013-1020, 2022 Oct 20.
Artigo em Inglês | MEDLINE | ID: mdl-36260091

RESUMO

BACKGROUND: Hair loss studies have mostly been clinical with no trichoscopy features of the hair loss documented in Nigeria. OBJECTIVE: The objective of this study was to determine the community prevalence, types of hair loss, trichoschopy features and the risk factors for the observed hair loss types. METHODS: This was a cross-sectional descriptive study of traders (Fitz Patrick's skin types V-VI) at an urban market. The traders were clinically evaluated for hair loss. Sociodemographic, clinical and trichoscopy data were recorded using a study questionnaire. Data was analyzed using SPSS version 22.0. Statistics such as means, medians, frequencies, t-test and chi-square test were presented. Levels of significance of all tests was set at, P<0.05%. RESULTS: A total of 307 participants (32.6% male and 67.4% female) with a mean age of 42.7±12.8 years were studied. The prevalence of hair loss was 68.7% (51% in males and 77.3% in females) and the mean age of those with hair loss was 44.8±12.3 years. The pattern of hair loss was patterned, diffuse and localized in 94.3%, 3.8% and 1.9% respectively. The main types of hair loss were androgenetic alopecia (26.9%) and traction alopecia (71.7%). The prevalent hair practices were; braids and weave-on (extensions) in 78.2%, turban-like head gear in 76.9%, and chemical relaxers in 73.8%. Trichoscopy features characteristic of the observed hair loss types were documented. CONCLUSION: Hair loss is common in the community. The common hair care practices and increasing age could be contributors to hair loss.


CONTEXTE: Les études sur la perte de cheveux ont surtout été cliniques et aucune caractéristique trichoscopique de la perte de cheveux n'a été documentée au Nigeria. OBJECTIF: L'objectif de cette étude était de déterminer la prévalence communautaire, les types de perte de cheveux, les caractéristiques de la trichoscopie et les facteurs de risque pour les types de perte de cheveux observés. MÉTHODES: Il s'agissait d'une étude descriptive transversale de commerçants (types de peau V-VI de Fitz Patrick) sur un marché urbain. Les commerçants ont été évalués cliniquement pour la perte de cheveux. Les données sociodémographiques, cliniques et trichoscopiques ont été enregistrées à l'aide d'un questionnaire d'étude. Les données ont été analysées à l'aide de SPSS version 22.0. Des statistiques telles que les moyennes, les médianes, les fréquences, le test t et le test du chi-deux ont été présentées. Le niveau de signification de tous les tests a été fixé à P<0,05%. RÉSULTATS: Un total de 307 participants (32,6% d'hommes et 67,4% de femmes) avec un âge moyen de 42,7±12,8 ans ont été étudiés. La prévalence de la perte de cheveux était de 68,7 % (51 % chez les hommes et 77,3 % chez les femmes) et l'âge moyen des personnes présentant une perte de cheveux était de 44,8±12,3 ans. La perte de cheveux était structurée, diffuse et localisée dans 94,3 %, 3,8 % et 1,9 % des cas respectivement. Les principaux types de perte de cheveux étaient l'alopécie androgénétique (26,9 %) et l'alopécie de traction (71,7 %). Les pratiques capillaires prédominantes étaient les suivantes : tresses et tissage (extensions) dans 78,2 % des cas, coiffure en turban dans 76,9 % des cas et défrisage chimique dans 73,8 % des cas. Les traits trichoscopiques caractéristiques des types de perte de cheveux observés ont été documentés. CONCLUSION: La perte de cheveux est fréquente dans la communauté. Les pratiques courantes de soins capillaires et l'âge croissant pourraient contribuer à cette perte de cheveux. Mots clés: Trichoscopie, Perte de cheveux, Pratique des soins capillaires, Communauté, Africaine, Prévalence.


Assuntos
Alopecia , Dermoscopia , Masculino , Feminino , Humanos , Adulto , Pessoa de Meia-Idade , Estudos Transversais , Prevalência , Dermoscopia/efeitos adversos , Nigéria/epidemiologia , Alopecia/epidemiologia , Alopecia/etiologia , Cabelo
10.
West Afr J Med ; 39(10): 1026-1031, 2022 Oct 20.
Artigo em Inglês | MEDLINE | ID: mdl-36260427

RESUMO

BACKGROUND: Androgenetic alopecia (AGA) is the most common form of alopecia, affecting 50% of the adult population world-wide. The exact mechanisms of this common hair disorder are yet to be fully elucidated. It is believed to be related to high circulating androgen levels in the blood and it is genetically determined. Deficiencies of micronutrients such as iron in the development of AGA have been a subject of debate. OBJECTIVE: This study sought to determine the association between serum ferritin levels and androgenetic alopecia among patients attending the Dermatology clinic at a tertiary health facility in South-Western Nigeria. METHODS: This was a hospital based cross sectional study with a total of 114 participants, which consisted of 57 subjects with AGA and 57 age and sex-matched healthy adults without AGAwho met the inclusion criteria. The diagnosis of AGA was made clinically and with the aid of a Dermatoscope (Wi-Fi Digital Microscope RoHS YPC_X03 V2018, HD Colour CMOS sensor with 50X-1000X magnification and HD resolution 1920x1080P). RESULTS: The mean age of the study participants was 41.68 ± 12.86 years with age ranging from 24 to 80 years. The mean serum ferritin levels among the subjects and control group were 188.65 ±97.92ng/ml and 194.49 ± 76.67ng/ml respectively but this difference was not statistically significant (p = 0.724). However, subjects with premature AGA had a significantly lower serum ferritin level compared to those with adult-onset AGA (p = 0.020). CONCLUSION: Iron deficiency is known to cause quantitative defect in haemoglobin production, limiting the amount of oxygen transported for hair growth and this, in addition to genetic factors, may explain why individuals with premature AGA have a significantly low serum ferritin levels.


CONTEXTE: L'alopécie androgénétique (AGA) est la forme la plus courante d'alopécie, affectant 50% de la population adulte dans le monde. Les mécanismes exacts de ce trouble capillaire commun n'ont pas encore été entièrement élucidés. On pense qu'il est lié à des taux élevés d'androgènes circulants dans le sang et qu'il est génétiquement déterminé. Les carences en micronutriments tels que le fer dans le développement de l'AGA ont fait l'objet de débats. OBJECTIF: Cette étude a cherché à déterminer l'association entre les niveaux de ferritine sérique et l'alopécie androgénétique chez les patients fréquentant la clinique de dermatologie d'un établissement de santé tertiaire du sud-ouest du Nigeria. MÉTHODES: Il s'agissait d'une étude transversale en milieu hospitalier avec un total de 114 participants, dont 57 sujets atteints d'AGA et 57 adultes en bonne santé, appariés selon l'âge et le sexe, sans AGA, qui répondaient aux critères d'inclusion. Le diagnostic de l'AGA a été établi cliniquement et à l'aide d'un dermatoscope (microscope numérique Wi-Fi RoHS YPC_X03 V2018, capteur CMOS couleur HD avec un grossissement de 50X-1000X et une résolution HD 1920x1080P). RÉSULTATS: L'âge moyen des participants à l'étude était de 41,68 ± 12,86 ans avec un âge allant de 24 à 80 ans. Les taux moyens de ferritine sérique chez les sujets et le groupe témoin étaient respectivement de 188,65 ± 97,92ng/ml et 194,49 ± 76,67ng/ml mais cette différence n'était pas statistiquement significative (p = 0,724). Cependant, les sujets atteints d'AGA prématurée avaient un taux de ferritine sérique significativement plus bas que ceux atteints d'AGA à l'âge adulte (p = 0,020). CONCLUSION: La carence en fer est connue pour provoquer un défaut quantitatif dans la production d'hémoglobine, limitant la quantité d'oxygène transportée pour la croissance des cheveux et ceci, en plus des facteurs génétiques, peut expliquer pourquoi les individus atteints d'AGA prématuré ont un taux de ferritine sérique significativement bas. Mots clés: Alopécie androgénétique, chute de cheveux, micronutriments, fer, ferritine, Nigeria.


Assuntos
Alopecia , Androgênios , Adulto , Idoso , Idoso de 80 Anos ou mais , Humanos , Pessoa de Meia-Idade , Adulto Jovem , Alopecia/epidemiologia , Alopecia/diagnóstico , Alopecia/etiologia , Estudos Transversais , Ferritinas , Hemoglobinas , Ferro , Micronutrientes , Nigéria/epidemiologia , Oxigênio
11.
Curr Opin Endocrinol Diabetes Obes ; 29(6): 535-540, 2022 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-36226726

RESUMO

PURPOSE OF REVIEW: To explore the recent updates in the diagnosis, management, and clinical implications of androgenic alopecia among patients diagnosed with polycystic ovarian syndrome (PCOS). RECENT FINDINGS: PCOS diagnosis continues to be the most common cause of infertility among reproductively aged women, serving as the most common endocrinopathy among this population. Female pattern hair loss (FPHL) has been seen to be associated and more common among patients with PCOS, however, there are limited studies examining the impact of FPHL among PCOS patients. Although hyperandrogenism is associated with FPHL, the pathophysiology continues to be unclear as FPHL can be present with normal biochemical androgen markers. Treatment can be complex, as common treatments to promote hair growth can exacerbate undesired hirsutism, which can be overcome by cosmetic treatments. New second-line treatment options such as low level laser therapy and platelet rich plasma have been emerging, with limited data supporting efficacy. SUMMARY: PCOS is a complex endocrinological disorder that has significant gynecologic, cutaneous, and metabolic implications that require multidisciplinary collaboration and care. Reproductive goals should be thoroughly discussed prior to starting any treatment, as PCOS is the most common cause of infertility among reproductively-aged women.


Assuntos
Hiperandrogenismo , Infertilidade , Síndrome do Ovário Policístico , Feminino , Humanos , Idoso , Hirsutismo/etiologia , Hirsutismo/terapia , Hirsutismo/epidemiologia , Síndrome do Ovário Policístico/complicações , Síndrome do Ovário Policístico/diagnóstico , Síndrome do Ovário Policístico/terapia , Androgênios/uso terapêutico , Hiperandrogenismo/complicações , Alopecia/diagnóstico , Alopecia/etiologia , Alopecia/terapia
14.
JAMA ; 328(7): 686, 2022 08 16.
Artigo em Inglês | MEDLINE | ID: mdl-35972484
16.
BMB Rep ; 55(11): 559-564, 2022 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-36016500

RESUMO

Diabetes mellitus is one of the most prevalent diseases in modern society. Many complicationssuch as hepatic cirrhosis, neuropathy, cardiac infarction, and so on are associated with diabetes. Although a relationship between diabetes and hair loss has been recently reported, the treatment of diabetic hair loss by Wnt/ß-catenin activators has not been achieved yet. In this study, we found that the depilation-induced anagen phase was delayed in both db/db mice and high-fat diet (HFD) and streptozotocin (STZ)-induced diabetic mice. In diabetic mice, both hair regrowth and wound-induced hair follicle neogenesis (WIHN) were reduced because of suppression of Wnt/ß-catenin signaling and decreased proliferation of hair follicle cells. We identified that KY19382, a small molecule that activates Wnt/ß-catenin signaling, restored the capabilities of regrowth and WIHN in diabetic mice. The Wnt/ß-catenin signaling activator also increased the length of the human hair follicle which was decreased under high glucose culture conditions. Overall, the diabetic condition reduced both hair regrowth and regeneration with suppression of the Wnt/ß-catenin signaling pathway. Consequently, the usage of Wnt/ß-catenin signaling activators could be a potential strategy to treat diabetes-induced alopecia patients. [BMB Reports 2022; 55(11): 559-564].


Assuntos
Alopecia , Diabetes Mellitus Experimental , Via de Sinalização Wnt , Animais , Humanos , Camundongos , Alopecia/etiologia , Alopecia/metabolismo , beta Catenina/metabolismo , Diabetes Mellitus Experimental/complicações , Diabetes Mellitus Experimental/metabolismo , Cabelo/metabolismo , Folículo Piloso/metabolismo
17.
Cancer Rep (Hoboken) ; 5(10): e1671, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-35861475

RESUMO

BACKGROUND: Intractable nasopharyngeal hemorrhage is a severe complication with high mortality rate in patients with radiation therapy (RT) for nasopharyngeal carcinoma (NPC) that requires emergency treatment. Quite a few of them combine with tumor recurrence. Treatment planning for these patients is extremely difficult for oncologists, and effective treatments are lacking. CASE: A 42-year-old man had a history of recurrent NPC that was treated with 2 cycles of chemoradiotherapies from 2017 to 2019. Five months after the second round of chemoradiotherapy, an episode of massive nasal bleeding occurred. As positron emission tomography (PET) scan revealed tumor recurrence in the left wall of nasopharynx, superselective embolization and subsequent intra-arterial infusion (IA, 4 times of cisplatin 60 mg + fluorouracil 1.0 g) were performed to stop bleeding and achieve tumor control. To date, the disease-free survival time has been over 1 year. No tumor recurrence or rebleeding is found except for alopecia on the left side. CONCLUSIONS: Interventional radiology is important and effective in the treatment of recurrent NPC for both massive nasal bleeding and tumor control. However, the unique complication of unilateral alopecia should not be ignored.


Assuntos
Cisplatino , Neoplasias Nasofaríngeas , Adulto , Alopecia/diagnóstico , Alopecia/etiologia , Alopecia/terapia , Protocolos de Quimioterapia Combinada Antineoplásica , Epistaxe/tratamento farmacológico , Fluoruracila/efeitos adversos , Humanos , Masculino , Carcinoma Nasofaríngeo/terapia , Neoplasias Nasofaríngeas/terapia
18.
Br J Dermatol ; 187(6): 1026-1028, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-35904062

RESUMO

This work reports 30 cases of folliculitis decalvans (FD) in patients with dystrophic epidermolysis bullosa (DEB) among a cohort of 125 DEB patients seen between 2010 and 2021 in 2 French expert centers for the management of inherited epidermolysis bullosa. Such an association between two rare diseases cannot be fortuitous and implies a physiopathological link that we discuss in this paper. This association is a new significant fact to add to the reflexion on FD causes, suggesting that skin abnormality of DEB could act as a factor of a specific skin barrier alteration which could favor FD. Scarring alopecia with tufted folliculitis and pustules on inflamed skin at the vertex of a woman with dominant dystrophic epidermolysis bullosa.


Assuntos
Epidermólise Bolhosa Distrófica , Epidermólise Bolhosa , Foliculite , Feminino , Humanos , Epidermólise Bolhosa Distrófica/complicações , Epidermólise Bolhosa Distrófica/patologia , Alopecia/etiologia , Alopecia/patologia , Pele/patologia , Foliculite/complicações , Epidermólise Bolhosa/patologia
19.
Ned Tijdschr Geneeskd ; 1662022 07 18.
Artigo em Holandês | MEDLINE | ID: mdl-35899755

RESUMO

A 6-month-old girl with an isolated bald spot was seen at the general practice. We diagnosed aplasia cutis congenita, a rare disorder with a wide variation in clinical symptoms. Most lesions can be managed conservatively. Larger defects, however, require surgery.


Assuntos
Displasia Ectodérmica , Doenças Raras , Couro Cabeludo , Alopecia/diagnóstico , Alopecia/etiologia , Displasia Ectodérmica/diagnóstico , Displasia Ectodérmica/patologia , Displasia Ectodérmica/cirurgia , Família , Feminino , Humanos , Lactente , Couro Cabeludo/patologia
20.
J Cosmet Dermatol ; 21(9): 3655-3662, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35801366

RESUMO

OBJECTIVE: While there are literature reporting increased incidence of hair loss in COVID-19 patients, insufficient evidence exists on the topic to date. This review aims to identify the existing evidence and clinical characteristics of hair loss with COVID-19 infection. METHODS: Following the PRISMA Extension for Scoping Reviews, MEDLINE and EMBASE were searched for all peer-reviewed articles with relevant keywords including "Alopecia," "Telogen Effluvium (TE)," and "COVID-19" from their inception to November 20, 2021. RESULTS: A total of 26 articles, with 9 observational studies and 17 case reports or series (a total of 58 cases), were included. Most studies dealt with TE. There were no clear trends between COVID-19 severity and the extent of hair loss. Analysis of the 58 cases also found similar results with most of the cases being female (82.8%), the median onset of hair loss of 2.0 months, and the median time to recovery of hair loss of 5.0 months with a resolution rate of 95%. CONCLUSION: While this systematic review revealed uncertainty and a lack of strong evidence regarding the association of COVID-19 and hair loss, hair loss in COVID-19 may mainly include TE and be reversible in nature. Future studies are warranted to determine the detailed pathophysiology and risk factors of hair loss in COVID-19, including possible roles of estrogen, progesterone, and pro-inflammatory cytokines.


Assuntos
Alopecia em Áreas , COVID-19 , Alopecia/complicações , Alopecia/etiologia , Alopecia em Áreas/etiologia , COVID-19/complicações , COVID-19/epidemiologia , Citocinas , Estrogênios , Feminino , Humanos , Masculino , Progesterona
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...