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1.
Rev Med Liege ; 76(2): 117-121, 2021 Feb.
Artigo em Francês | MEDLINE | ID: mdl-33543858

RESUMO

Androgenic alopecia is a genetically determined and leads to a progressive hair loss of the vertex, affecting both men and women. It is related to an important psychological and social distress. Medical therapies include topical minoxidil, oral 5?-reductase inhibitors and oestroprogestative drugs with anti-androgen effects for women. The surgical option is autograft hair transplantation. Recently, phototherapy with low-level energy lasers became available. All these treatments may present adverse effects and their effectiveness is questionable. Subcutaneous injections of autologous platelet-rich plasma into the scalp represent an interesting alternative treatment for androgenetic alopecia, as monotherapy or as an adjuvant treatment. The methodology, the possible mechanisms of action and some initial clinical results of this treatment are presented.


Assuntos
Alopecia , Plasma Rico em Plaquetas , Alopecia/terapia , Feminino , Humanos , Masculino , Minoxidil , Couro Cabeludo , Resultado do Tratamento
2.
Support Care Cancer ; 29(1): 437-443, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-32388615

RESUMO

PURPOSE: Scalp cooling during chemotherapy infusion has been recently reported to have moderate efficacy in the mitigation of chemotherapy-induced alopecia; however, there are few reports on Asian patients. We aimed to clarify the effects of scalp cooling in Japanese women. PATIENTS AND METHODS: Female Japanese breast cancer patients who planned to receive (neo)adjuvant chemotherapy participated in this prospective study on the efficacy of scalp cooling using the Paxman Scalp Cooling System for alopecia prevention. The primary outcomes were the rates of patients with Grade 3 alopecia (defined as hair loss of > 50%) and the rates of patients who used a wig or hat to conceal hair loss 1 month after the last infusion of chemotherapy. The subjects were given a brief questionnaire regarding headaches, bad mood, fatigue, and chills shortly after each cooling. RESULTS: One hundred and forty-three patients participated in the study and used the cooling cap at least once. The mean and median ages of the subjects were 50.6 and 50, respectively (age range 28-76). One hundred and twenty-nine patients completed the planned chemotherapy of 4 to 8 cycles. Among them (7 patients were not evaluable), 74 patients (60.7%) had Grade 3 alopecia 1 month after chemotherapy. Of 80 patients who used the scalp cooling system throughout the planned chemotherapy (1 patient was not evaluable), 36 patients (45.6%) experienced Grade 3 alopecia. CONCLUSION: The efficacy of scalp cooling during chemotherapy infusion for hair loss mitigation in Asian women is similar to that in Caucasian women.


Assuntos
Alopecia/prevenção & controle , Alopecia/terapia , Protocolos de Quimioterapia Combinada Antineoplásica/efeitos adversos , Neoplasias da Mama/complicações , Neoplasias da Mama/terapia , Hipotermia Induzida/métodos , Couro Cabeludo/irrigação sanguínea , Adulto , Idoso , Alopecia/induzido quimicamente , Feminino , Humanos , Japão , Pessoa de Meia-Idade , Estudos Prospectivos
3.
J Anesth Hist ; 6(3): 172-173, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32921493

RESUMO

Joseph Burnett manufactured the diethyl ether used for William T.G. Morton's public demonstration of inhaled surgical anesthesia on October 16, 1846 (Ether Day). A later Burnett product was a hairdressing oil claimed to prevent baldness and dandruff. It contained cocoa-nut oil and was called Cocoaine. In 1902 and 1903, it was sometimes advertised as Burnett's Cocaine (rather than Cocoaine), possibly to emulate the economic success of coca-based beverages such as Vin Mariani and Coca-Cola. Coca leaves are now decocainized before use in preparation of Coca-Cola, and the recovered cocaine is used for scientific and dwindling medical purposes.


Assuntos
Cocaína/história , Caspa/história , Preparações para Cabelo/história , Publicidade/história , Alopecia/história , Alopecia/terapia , Anestésicos Inalatórios/história , Cacau , Caspa/terapia , Éter/história , Preparações para Cabelo/química , História do Século XIX , Humanos
4.
J Cosmet Dermatol ; 19(11): 2974-2981, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32945026

RESUMO

BACKGROUND: Hair loss affects most people at some point in their lifetime, causing anxiety and decreased self-esteem. There are multiple surgical and nonsurgical treatments available, with the surgical options having greater and longer-lasting effects. Such treatments have evolved over time with advances in technology and research, with numerous patients researching these treatments on Google. Many surgeons who provide these treatments belong to the International Society of Hair Restoration Surgeons (ISHRS). AIMS: To investigate trends in surgical hair restoration treatment from both the surgeon and patient perspectives. METHODS: Patient epidemiological and surgical data from the ISHRS were combined with search trend data from Google to analyze changing trends in surgical hair restoration treatment. RESULTS: Worldwide Internet searches for "hair transplant" have increased from 2004 to the present. Follicular unit excision (FUE) has supplanted follicular unit transplant (FUT) as the most popular hair transplant performed. Since 2004, there has been an increase in both nonsurgical and surgical female patients. Beard and eyebrow transplants have increased in popularity. Google searches follow this trend. Nonsurgical treatments such as platelet-rich plasma (PRP) are being searched more frequently. Hair restoration clinics and Google searches were affected adversely by the COVID-19 pandemic. CONCLUSION: Technological advances in available therapies, improvement in delivery systems, changes in hair fashion, and global events have direct impact on hair restoration treatments offered by physicians and researched by patients. It is in the best interest of all hair restoration providers to keep abreast of changing technologies and treatment trends to stay at the forefront of their profession.


Assuntos
Alopecia/terapia , Betacoronavirus , Infecções por Coronavirus/epidemiologia , Técnicas Cosméticas/estatística & dados numéricos , Pneumonia Viral/epidemiologia , Padrões de Prática Médica/estatística & dados numéricos , Humanos , Pandemias , Mídias Sociais , Inquéritos e Questionários
5.
Medicine (Baltimore) ; 99(17): e19842, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32332635

RESUMO

INTRODUCTION: Seborrheic alopecia (SA) has clinical manifestations, duration of disease, and priorities. In the current situation where there are many and complicated clinical treatments, Western medicine treatment can delay and control the development of the disease and promote hair regeneration. However, some patients may aggravate symptoms after taking the drug, and the condition is easy to repeat after stopping the drug. Acupuncture is an important method for non-surgical treatment of SA, and it has various methods, low side effects, high safety, and simple and economical. Therefore, we will use a clinical randomized controlled study to explore the effect of acupuncture on SA, and provide a new idea and reference for the treatment of this disease. METHODS/DESIGN: We will select 60 patients diagnosed with SA. They will be randomly divided into intervention group and control groups. The control group will be given conventional treatment measures. The intervention group will receive acupuncture. Efficacy will be evaluated by comparing the skin lesion score and dermatological quality of life index before and after treatment. DISCUSSION: This trial may provide evidence regarding the clinical effectiveness, safety, and cost-effectiveness of acupuncture for patients with SA. TRIAL REGISTRATION NUMBER: CTR2000030430.


Assuntos
Terapia por Acupuntura , Alopecia/etiologia , Alopecia/terapia , Dermatite Seborreica/complicações , Terapia por Acupuntura/economia , Adolescente , Adulto , Análise Custo-Benefício , Humanos , Masculino , Pessoa de Meia-Idade , Qualidade de Vida , Resultado do Tratamento , Adulto Jovem
6.
J Biomed Sci ; 27(1): 43, 2020 Mar 14.
Artigo em Inglês | MEDLINE | ID: mdl-32171310

RESUMO

Stem cell activity is subject to non-cell-autonomous regulation from the local microenvironment, or niche. In adaption to varying physiological conditions and the ever-changing external environment, the stem cell niche has evolved with multifunctionality that enables stem cells to detect these changes and to communicate with remote cells/tissues to tailor their activity for organismal needs. The cyclic growth of hair follicles is powered by hair follicle stem cells (HFSCs). Using HFSCs as a model, we categorize niche cells into 3 functional modules, including signaling, sensing and message-relaying. Signaling modules, such as dermal papilla cells, immune cells and adipocytes, regulate HFSC activity through short-range cell-cell contact or paracrine effects. Macrophages capacitate the HFSC niche to sense tissue injury and mechanical cues and adipocytes seem to modulate HFSC activity in response to systemic nutritional states. Sympathetic nerves implement the message-relaying function by transmitting external light signals through an ipRGC-SCN-sympathetic circuit to facilitate hair regeneration. Hair growth can be disrupted by niche pathology, e.g. dysfunction of dermal papilla cells in androgenetic alopecia and influx of auto-reacting T cells in alopecia areata and lichen planopilaris. Understanding the functions and pathological changes of the HFSC niche can provide new insight for the treatment of hair loss.


Assuntos
Alopecia/terapia , Folículo Piloso/fisiologia , Cabelo/fisiologia , Regeneração , Nicho de Células-Tronco , Células-Tronco/fisiologia , Animais , Diferenciação Celular , Folículo Piloso/fisiopatologia , Humanos , Camundongos
7.
Plast Surg Nurs ; 40(1): 6-19, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32102074

RESUMO

In this article, the author focuses on 4 common hair loss disorders that occur in both men and women. The author discusses research related to androgenetic alopecia, telogen effluvium, alopecia areata, and scarring alopecia and provides details on how to approach and manage these diseases according to patient gender. There are a range of tools and tests that can assist with the diagnostic process and help ensure that relevant and high standards of patient care are maintained. In some cases, no medical intervention is always a treatment option. However, appropriate medical treatments, although still relatively limited in some cases, are safe and have proven efficacy. Hair loss has immense emotional and psychological impact in both genders, and it is always important to consider this when planning hair loss management pathways.


Assuntos
Alopecia/classificação , Alopecia/terapia , Feminino , Humanos , Masculino
8.
Biomed Res Int ; 2020: 7397162, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32071919

RESUMO

Tissue engineering in hair regrowth aims to develop innovative and not-invasive procedures to advance the hair regrowth. A placebo-controlled, randomized, evaluator-blinded, half-head group study to compare hair regrowth with micrografts containing human hair follicle mesenchymal stem cells (HF-MSCs) vs. placebo was reported. After 58 weeks, 27 patients displayed in the targeted area an increase of hair count and hair density, respectively, of 18.0 hairs per 0.65 cm2 and 23.3 hairs per cm2 compared with baseline, while the control area displayed a mean decrease of 1.1 hairs per 0.65 cm2 and 0.7 hairs per cm2 (control vs. treatment: P < 0.0001). After 26 months, 6 patients revealed dynamic hair loss and were retreated. More broad controlled examinations are required. HF-MSCs contained in micrografts may represent a safe and viable treatment alternative against hair loss.


Assuntos
Alopecia/terapia , Folículo Piloso/transplante , Couro Cabeludo , Adulto , Alopecia/patologia , Feminino , Cabelo/crescimento & desenvolvimento , Humanos , Masculino , Couro Cabeludo/patologia , Transplante de Pele/métodos , Transplantes
9.
Dermatol Surg ; 46(1): 93-102, 2020 01.
Artigo em Inglês | MEDLINE | ID: mdl-31211715

RESUMO

BACKGROUND: The use of platelet-rich plasma is becoming more prevalent in the field of dermatology. Variable preparation techniques and treatment methods have been described with reported success in alopecia. OBJECTIVE: To consolidate the available evidence of platelet-rich plasma and its utility in the treatment of alopecia for the practicing dermatologist. METHODS: Evaluating the available evidence up to May 31, 2018, a search was conducted in the PubMed database for "platelet rich plasma" or "platelet releasate" or "platelet gel" or "PRP" and "dermatology" or "skin" or "hair" or "cutaneous." RESULTS: Nineteen articles met the inclusion criteria for analysis including 3 alopecia areata studies with a total of 71 patients and 16 androgenetic alopecia studies with a total of 389 patients. Although the heterogeneity of the studies prevented direct comparisons and subsequent statistical analysis, the majority demonstrated that platelet-rich plasma produced successful hair growth in androgenetic alopecia and alopecia areata. CONCLUSION: This review advocates for the use of platelet-rich plasma in 3 to 4 monthly sessions for the treatment of alopecia. Future studies should include a detailed description of the platelet-rich plasma isolation process to allow for comparison among studies, provide reproducibility, and generate a standardized treatment protocol.


Assuntos
Alopecia/terapia , Plasma Rico em Plaquetas , Humanos
12.
Am J Clin Dermatol ; 21(1): 69-84, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31677111

RESUMO

Female androgenetic alopecia (FAGA) is a common cause of non-scarring alopecia in women. The onset may be at any age following puberty and the frequency increases with age. Clinically, it shows a diffuse hair thinning over the central scalp, while the frontal hairline is usually retained. FAGA can have a significant psychological impact, leading to anxiety and depression. For this reason, early diagnosis is very important to stop the progression of the disease. The sex hormonal milieu is the main pathogenetic mechanism studied in FAGA. The role of androgens is not clearly defined and only one-third of women with FAGA show abnormal androgen levels. Endocrinological diseases with hyperandrogenism associated with FAGA comprise polycystic ovarian syndrome (PCOS), hyperprolactinemia, adrenal hyperplasia and, rarely, ovarian and adrenal tumours. Usually the diagnosis of FAGA is made clinically. A complete clinical examination and a blood examination can reveal other signs of hyperandrogenism. Trichoscopy shows the typical hair miniaturization. A scalp biopsy can be useful when the clinical evaluation does not provide a definitive diagnosis or when cicatricial alopecias with hair loss in the distribution of FAGA or alopecia areata are suspected. FAGA is a slowly progressive disease. The goal of therapy is to stop the progression and to induce a cosmetically acceptable hair regrowth. The most important drugs are topical minoxidil and oral anti-androgens. The purpose of this review is to provide an update on FAGA and to create a guideline on diagnosis and management of this frequent hair disease, not always easily recognizable from cicatricial alopecias with a similar distribution.


Assuntos
Alopecia/terapia , Cabelo/crescimento & desenvolvimento , Alopecia/diagnóstico , Alopecia/fisiopatologia , Antagonistas de Androgênios/administração & dosagem , Progressão da Doença , Feminino , Cabelo/anormalidades , Humanos , Hiperandrogenismo/complicações , Minoxidil/administração & dosagem
13.
Dermatol Surg ; 46(4): 447-456, 2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-31770154

RESUMO

BACKGROUND: Platelet-rich plasma (PRP) is an increasingly popular treatment modality for various dermatologic conditions, but there are limitations in both the published literature and clinician knowledge. OBJECTIVE: To create a high-yield, in-depth analysis of PRP in procedural dermatology by reviewing available data on its role in hair restoration, soft-tissue remodeling, resurfacing, and rejuvenation; identifying practice gaps and controversies; and making suggestions for future research that will establish dermatologists as pioneers of regenerative medicine. MATERIALS AND METHODS: A two-part systematic review and expert analysis of publications before October 2018. RESULTS AND CONCLUSION: Most studies on PRP report favorable outcomes with the strongest level of evidence existing for androgenetic alopecia followed by postprocedure wound healing, scar revision, striae, rejuvenation, and dermal filling. There is a dearth of large randomized controlled trials, considerable heterogeneity in the variables studied, and lack of specificity in the preparatory protocols, which may influence clinical outcomes. Future investigations should use consistent nomenclature, find ideal solution parameters for each cutaneous indication, determine significant outcome metrics, and follow double-blinded, randomized, controlled methodologies. Addressing these deficiencies will take sound scientific inquiry but ultimately has the potential to benefit the authors' specialty greatly.


Assuntos
Dermatologia/normas , Medicina Baseada em Evidências/normas , Plasma Rico em Plaquetas/fisiologia , Guias de Prática Clínica como Assunto , Alopecia/terapia , Cicatriz/terapia , Tomada de Decisão Clínica , Dermatologia/métodos , Medicina Baseada em Evidências/métodos , Humanos , Seleção de Pacientes , Rejuvenescimento/fisiologia , Envelhecimento da Pele/fisiologia , Cicatrização/fisiologia
15.
Indian J Dermatol Venereol Leprol ; 86(2): 150-157, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31823902

RESUMO

Background: Male-type baldness is a common chronic hair loss disorder among males. Male type baldness is characterized by stepwise miniaturization of the hair follicle, due to alteration in the hair cycle dynamics, leading to transformation of the terminal hair follicle into a vellus one. Platelet-rich plasma (PRP) seems to be a new technique which may improve hair regrowth. We planned a randomized, double-blinded placebo control trial to see the efficacy of PRP with and without topical minoxidil and to compare with placebo and standard treatment. Materials and Methods: The study design was a randomized, double-blind placebo control trial. The sample size was calculated, and randomization was done. Patients with male type baldness were allocated into four groups; first group topical minoxidil only, the second group PRP with minoxidil, the third group normal saline (NS), and fourth group PRP only. Interventions were done monthly for 3 months and patients were followed up for the next 2 months. Effects of interventions were assessed by hair density, patient self-assessment, and clinical photography. Results: A total of 80 patients were included. The maximum improvement was found in PRP with minoxidil group. Increase in hair density (in descending order) was PRP with minoxidil group, PRP-alone group, minoxidil-alone group, while a decrease in hair density was found in NS group, after 5 months. The maximum patient satisfaction was found in PRP with minoxidil group followed by (in descending order), PRP-alone group, minoxidil-alone group, and NS group. Limitation: Long-term follow up of patients was not done. Hair counts and hair thickness estimation were not estimated. Conclusion: In our study, we found PRP with topical minoxidil is more effective than PRP alone and topical minoxidil alone.


Assuntos
Alopecia/diagnóstico , Alopecia/terapia , Minoxidil/administração & dosagem , Plasma Rico em Plaquetas , Vasodilatadores/administração & dosagem , Administração Tópica , Adulto , Terapia Combinada/métodos , Método Duplo-Cego , Seguimentos , Folículo Piloso/efeitos dos fármacos , Folículo Piloso/crescimento & desenvolvimento , Humanos , Masculino , Plasma Rico em Plaquetas/fisiologia , Estudos Prospectivos , Resultado do Tratamento , Adulto Jovem
16.
J Cosmet Dermatol ; 19(1): 75-77, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31066492

RESUMO

Androgenetic alopecia (AGA) is the most common type of alopecia. Currently, only topical minoxidil and oral finasteride, for men, are approved for its treatment. We report a case of a patient with male pattern AGA treated with topical minoxidil and oral finasteride for 2 years, with partial improvement. At this point, we added mesotherapy to the previous treatment. The patient had 20 sessions of sterile mesotherapy blend, containing minoxidil, finasteride, biotin, and D-panthenol. We did the injections every two weeks and made the response assessment with global clinical photographs at the 10th and the 20th sessions when we noted a significant visible improvement in hair density and thickness. Mesotherapy or intradermotherapy is defined as a technique that involves the use of multiple intradermal injections of a mixture of compounds in low doses, at many points, near/over the affected sites. In our case, the patient had an excellent response to intradermotherapy as an adjunctive treatment, with no side effects. Although we still need additional clinical trials to standardize the therapy and treatment guidelines, mesotherapy seems to be a therapeutic option in the treatment of AGA, especially if the procedure happens in a medical facility, with correct indication and adequate execution of this promising technique.


Assuntos
Alopecia/terapia , Finasterida/administração & dosagem , Mesoterapia , Minoxidil/administração & dosagem , Administração Oral , Administração Tópica , Terapia Combinada/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
17.
Clin Dermatol ; 37(6): 618-628, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31864440

RESUMO

Alopecia is a skin condition of great social and psychologic impact. Primary alopecia originates from the hair follicles and usually does not have systemic manifestations; however, secondary alopecia can affect the hair follicles in the setting of systemic diseases, medications, and external trauma. Connective tissue diseases, granulomatous diseases, bullous diseases, infections, and tumors are some of the systemic diseases that will be covered in this review. Trichoscopy is a useful noninvasive tool that can help with the diagnosis in the office and can guide the selection of the optimal site for the scalp biopsy. Histopathology is the ultimate tool for the diagnosis in most cases of secondary alopecia and can be performed on vertical and horizontal sections. In most cases, treating the underlying condition is the single most important strategy, but topical treatments for the alopecia are also applied.


Assuntos
Alopecia , Dermatopatias , Alopecia/classificação , Alopecia/etiologia , Alopecia/terapia , Amiloidose/complicações , Doenças do Tecido Conjuntivo/complicações , Dermatomiosite/complicações , Epidermólise Bolhosa/complicações , Humanos , Lúpus Eritematoso Discoide/complicações , Lúpus Eritematoso Sistêmico/complicações , Transtornos Linfoproliferativos/complicações , Pênfigo/complicações , Psoríase/complicações , Sarcoidose/complicações , Escleroderma Sistêmico/complicações , Sífilis/complicações , Tinha do Couro Cabeludo/complicações
18.
Acta Dermatovenerol Alp Pannonica Adriat ; 28(4): 169-171, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31855270

RESUMO

INTRODUCTION: Medical treatment of androgenetic alopecia (AGA) is mainly limited to pharmacological and surgical interventions. Patients' desire for noninvasive and non-systemic treatments has accelerated research into medical devices that can promote hair growth. Low-level laser therapy (LLLT) was the first such device. However, its success has been limited by contradictory and often controversial efficacy claims. Work previously performed in animal models of AGA has demonstrated the viability of the wound repair mechanism as a potential treatment modality. This study therefore explores the use of a non-ablative radio frequency (RF) device in the treatment of AGA. METHODS: A single blindedstudy compared a non-ablative RF device versus a sham device in 24 men with AGA. Each subject received four treatments over the 12-week study. RESULTS: In this preliminary study of 24 AGA patients treated with a novel RF device, we demonstrated that 54% showed a clinical response. Furthermore, among patients that underwent four or more treatment sessions, 40% experienced a 30% or more increase in hair counts compared to baseline. CONCLUSIONS: If validated in a larger cohort, non-ablative RF may prove to be an important clinical tool in the treatment of AGA.


Assuntos
Alopecia/terapia , Terapia por Radiofrequência , Adulto , Humanos , Masculino , Pessoa de Meia-Idade , Método Simples-Cego , Resultado do Tratamento , Adulto Jovem
19.
Skin Therapy Lett ; 24(5): 1-6, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31584784

RESUMO

Platelet-rich plasma (PRP) is an autologous serum containing high concentrations of platelets and growth factors. PRP continues to evolve as an important treatment modality with many applications in dermatology, particularly in the areas of hair restoration, skin rejuvenation, acne scars, dermal augmentation, and striae distensae. Furthermore, combining PRP with laser therapies, microneedling, dermal fillers, and autologous fat grafting produces synergistic effects, leading to improved aesthetic results. Future studies should standardize PRP treatment protocols for specific indications. PRP holds considerable promise in dermatology with therapeutic applications continuing to expand.


Assuntos
Dermatologia , Plasma Rico em Plaquetas , Alopecia/terapia , Cicatriz/terapia , Técnicas Cosméticas , Humanos , Rejuvenescimento , Estrias de Distensão/terapia
20.
Dermatol Online J ; 25(8)2019 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-31553869

RESUMO

Folliculitis decalvans is a rare scarring alopecia that presents with indurated, tender pustules and papules on the vertex and occipital scalp. Although systemic antibiotics with activity against Staphylococcus species provide some symptomatic improvement, folliculitis decalvans remains a significant management challenge and often exhibits a relapsing-and-remitting course. In this report, we posit the potential utility of medical grade honey as a safe and cost-effective adjuvant therapy in the treatment of folliculitis decalvans. We describe a patient with painful, boggy scalp pustules who achieved clearance of his scalp lesions with the addition of Manuka honey. To our knowledge, this report is the first to demonstrate the clinical use of honey in the management of folliculitis decalvans and may lend support to the role of Staphylococcus in the pathogenesis of this disease.


Assuntos
Alopecia/terapia , Foliculite/terapia , Mel , Dermatoses do Couro Cabeludo/terapia , Infecções Cutâneas Estafilocócicas/terapia , Alopecia/etiologia , Alopecia/patologia , Antibacterianos/uso terapêutico , Cefalexina/uso terapêutico , Foliculite/complicações , Foliculite/patologia , Glucocorticoides/uso terapêutico , Humanos , Injeções Intralesionais , Masculino , Dermatoses do Couro Cabeludo/complicações , Dermatoses do Couro Cabeludo/patologia , Infecções Cutâneas Estafilocócicas/complicações , Infecções Cutâneas Estafilocócicas/patologia , Falha de Tratamento , Adulto Jovem
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