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INTRODUCTION: surgical pain is managed with multi-modal anesthesia in total knee arthroplasty (TKA). It is dubious whether including local infiltrative anaesthesia (LIA) before wound closure provides adequate pain control and decreases morbidity. MATERIAL AND METHODS: this was a retrospective conducted to assess postoperative pain control, morbidity index, and opioid consumption in 116 patients who underwent TKA and were divided into two groups based on LIA (Modified Ranawat Regimen) or normal saline infiltration in the wound. RESULTS: the mean NRS score was significantly lower in LIA group (3.2) as compared to the control group (3.9) in the first 24 hours. Functional milestones were relatively achieved earlier in LIA group but the values were not significant. Tramadol consumption was remarkably higher in the control group as compared to LIA group on day 1 and 2. As per the morbidity index the mean score on day one was 16.18 and 23.40 which decreased to 6.37 and 9.21 by day three in LIA and control group respectively indicating morbidity has decreased but more so in LIA group. CONCLUSION: our study concludes that use of modified cocktail regimen in the knee effectively decreased morbidity with excellent to good results, declining NRS score, minimal rescue analgesia requirement, early ambulation with better safety.
INTRODUCCIÓN: el dolor quirúrgico se trata con anestesia multimodal en la artroplastia total de rodilla (ATR). Es dudoso que incluir anestesia local infiltrativa (LIA) antes del cierre de la herida proporcione un control adecuado del dolor y disminuya la morbilidad. MATERIAL Y MÉTODOS: se realizó una retrospectiva para evaluar el control del dolor posoperatorio, el índice de morbilidad y el consumo de opioides en 116 pacientes sometidos a ATR y se dividieron en dos grupos según el LIA (régimen de Ranawat modificado) o la infiltración de solución salina normal en la herida. RESULTADOS: la puntuación media NRS fue significativamente menor en el grupo LIA (3.2) en comparación con el grupo control (3.9) en las primeras 24 horas. Los hitos funcionales se alcanzaron relativamente antes en el grupo LIA, pero los valores no fueron significativos. El consumo de tramadol fue notablemente mayor en el grupo de control en comparación con el grupo de LIA los días 1 y 2. Según el índice de morbilidad, la puntuación media el día uno fue 16.18 y 23.40, que disminuyó a 6.37 y 9.21 en el día tres en el grupo de LIA y control, respectivamente, lo que indica que la morbilidad ha disminuido, pero más en el grupo LIA. CONCLUSIÓN: nuestro estudio concluye que el uso de un régimen de cóctel modificado en la rodilla disminuyó efectivamente la morbilidad con resultados excelentes a buenos, una disminución de la puntuación NRS, un requisito mínimo de analgesia de rescate y una deambulación temprana con mayor seguridad.
Assuntos
Anestésicos Locais , Artroplastia do Joelho , Dor Pós-Operatória , Humanos , Estudos Retrospectivos , Artroplastia do Joelho/métodos , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/prevenção & controle , Feminino , Masculino , Pessoa de Meia-Idade , Idoso , Anestésicos Locais/administração & dosagem , Anestésicos Locais/uso terapêutico , Centros de Atenção Terciária , Analgésicos Opioides/administração & dosagem , Analgésicos Opioides/uso terapêutico , Anestesia Local/métodos , Resultado do Tratamento , Tramadol/administração & dosagem , Tramadol/uso terapêutico , Medição da DorRESUMO
OBJECTIVE: To assess the clinical scenarios in which nerve blocks are employed in the context of burning mouth syndrome (BMS). STUDY DESIGN: This scoping review followed the PRISMA-ScR. A protocol was generated on Open Science Framework. Electronic searches were performed in the following databases: PubMed, Scopus, EMBASE, Web of Science, LILACS, and Cochrane, in addition to the grey literature and citations from Grémeau-Richard et al. (2010). RESULTS: Nerve blocks were used for treatment purposes in all cases. The mandibular nerve and the stellate ganglion were both blocked in 50% studies, while the maxillary nerve and lingual nerve were blocked in 25% study each. The anesthetics used were lidocaine (50%) and bupivacaine (50%). Relief was generally reported after immediate block, and at a mean follow-up of 4.5 weeks, there was considerable improvement compared to the initial conditions when the mandibular and/or maxillary nerve were targeted. CONCLUSIONS: The use of nerve blocks has been employed in the treatment of patients with refractory BMS. Clinical studies with standardized methodology are necessary to validate and understand the potential role of mandibular and maxillary nerve block in this setting.
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Anestésicos Locais , Síndrome da Ardência Bucal , Bloqueio Nervoso , Humanos , Síndrome da Ardência Bucal/terapia , Bloqueio Nervoso/métodos , Anestésicos Locais/administração & dosagem , Anestesia Local/métodos , Lidocaína/administração & dosagemRESUMO
BACKGROUND: Anxiety during oral surgery can impact patient homeostasis, increase the difficulty of the procedure and create additional stress for the surgeon. Furthermore, it has been associated with more intense and prolonged pain during and after dental treatment. OBJECTIVES: The aim of the study is to evaluate the relationship between anxiety, patient characteristics and pain outcomes in oral surgery, as well as to verify the impact of anxiety on patient's perception of pain during and after oral surgery. MATERIAL AND METHODS: This is a prospective observational study. Several variables were evaluated during the course of the oral surgery. Anxiety levels were assessed using the State-Trait Anxiety Inventory (STAI), Corah's Dental Anxiety Scale (DAS), the Interval Scale of Anxiety Response (ISAR), and Patient SelfRated Anxiety (PAnx) during the procedure. RESULTS: General anxiety measures (STAI) were not associated with specific dental anxiety or external observations of anxiety. Anxiety levels varied according to gender and body mass index (BMI), and were correlated with increased heart rate (HR) (with variability among assessment tools). Odontectomy, ostectomy and an increased volume of anesthesia were associated with higher anxiety levels (with variability among the assessment tools). There was a correlation between pain and anxiety, with anxiety contributing to approx. 12% of the variability in postoperative pain. CONCLUSIONS: Dental anxiety is a complex, multidimensional mental phenomenon characterized by high variability due to the influence of several dynamic factors.
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Anestesia Local , Ansiedade ao Tratamento Odontológico , Medição da Dor , Dor Pós-Operatória , Humanos , Feminino , Masculino , Estudos Prospectivos , Dor Pós-Operatória/psicologia , Pessoa de Meia-Idade , Adulto , Procedimentos Cirúrgicos Bucais/efeitos adversos , Procedimentos Cirúrgicos Bucais/psicologia , Idoso , AnsiedadeRESUMO
Deep brain stimulation (DBS) stands as the preferred treatment for Parkinson's disease (PD) patients manifesting refractory motor symptoms or when medication side effects outweigh the benefits. Though traditionally administered under local anesthesia coupled with sedation (LA + S), recent evidence hints at comparable outcomes under general anesthesia (GA). This systematic review and meta-analysis aimed to scrutinize post-surgical outcomes in randomized PD patients undergoing DBS surgery while GA versus LA + S. We searched PubMed, Cochrane, and Embase databases following PRISMA guidelines. We included randomized studies directly comparing DBS surgery under GA versus LA + S, delineating clinical outcomes. Safety outcomes assessed disparities in infection and hemorrhage risk. Mean differences (MD) and Risk Differences (RD) with 95% Confidence Intervals (CI) were utilized to evaluate outcomes, under a random-effects model. Heterogeneity was evaluated through I² statistics, and in studies exhibiting high heterogeneity, exclusion analysis was performed. Evaluated outcomes encompassed motor improvement, complications, behavioral and mood effects gauged by the Unified Parkinson's Disease Rating Scale (UPDRS), Parkinson's Disease Questionnaire 39 (PDQ39), and daily levodopa equivalent dose (LEDD). A total of 3 studies, encompassing 203 patients, were reviewed. At a 6-month follow-up, in patients undergoing GA during surgery, there was no statistically significant difference compared to the LA + S group in terms of UPDRS III ON (MD 0.19; 95% CI -2.21 to 2.59; p = 0.88; I²=0%), UPDRS III OFF (MD 0.58; 95% CI -4.30 to 5.45; p = 0.21; I²=0%), UPDRS IV ON ( (MD 0.98; 95% CI -0.95 to 2.92; p = 0.32; I²=23%), PDQ39 (MD -1.27; 95% CI -6.31 to 3.77; p = 0.62; I²=0%), and LEDD (MD -1.99; 95% CI -77.88 to 73.90; p = 0.96; I²=32%). There was no statistically significant difference between groups in terms of infection (RD 0.02; 95% CI -0.02 to 0.05; p = 0.377; I²=0%) or hemorrhage (RD 0.04; 95% CI -0.03 to 0.11; p = 0.215; I²=0%). Our findings suggest, based on short-term follow-up, that GA is not inferior to LA + S in terms of benefits for the selected outcomes. However, further studies are needed to determine whether there are significant long-term clinical differences between these groups.
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Anestesia Geral , Anestesia Local , Estimulação Encefálica Profunda , Doença de Parkinson , Ensaios Clínicos Controlados Aleatórios como Assunto , Núcleo Subtalâmico , Humanos , Anestesia Geral/métodos , Anestesia Local/métodos , Estimulação Encefálica Profunda/métodos , Doença de Parkinson/terapia , Núcleo Subtalâmico/cirurgia , Resultado do TratamentoAssuntos
Anestesia Local , Dedo em Gatilho , Humanos , Anestesia Local/métodos , Dedo em Gatilho/cirurgia , CriançaRESUMO
BACKGROUND: Endovascular treatment of intracranial aneurysms (EVTIAs) is increasingly popular due to its minimally invasive nature and high success rate. While general anesthesia (GA) has been the historical preference for EVTIAs, there's growing interest in local anesthesia (LA). However, concerns persist about LA safety for EVTIAs. Therefore, we conducted a systematic review and meta-analysis to assess LA safety for EVTIAs. METHODS: Following PRISMA guidelines, we searched PubMed, Embase, and Web of Science databases. Pooled analysis with 95 % confidence intervals (CI) assessed effects, I2 statistics gauged heterogeneity, and a random-effects model was adopted. Conversion to GA, neurological or procedure-related complications, intraoperative intracranial hemorrhagic complications (IIHC), and mortality were assessed. Subanalyses for ruptured and unruptured cases were performed. RESULTS: The analysis included eleven studies, 2,133 patients, and 2,369 EVTIAs under LA. Conversion to GA rate was 1 % (95 %CI: 0 to 2 %). Neurological or procedure-related complications rate was 13 % (95 % CI: 8 % to 17 %). IIHC analysis revealed a rate of 1 % (95 % CI: 1 % to 2 %). The mortality rate was 0 % (95 %CI: 0 % to 0 %). Subanalyses revealed similar rates in ruptured and unruptured subgroups, except for a slightly high rate of complications and IIHC in the ruptured subgroup. CONCLUSION: Findings indicate that EVTIA under LA is safe, with low conversion and mortality rates, even for ruptured aneurysms. Complications rates, also in IIHC rates, are comparable to those reported for GA, emphasizing LA's comparable safety profile in EVTIAs. Considering these promising outcomes, the decision to opt for the LA approach emerges as meaningful and well-suited for the endovascular treatment of aneurysms. Beyond its safety, LA introduces inherent supplementary advantages, including shortened hospitalization periods, cost-effectiveness, and an expedited patient recovery process.
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Anestesia Local , Procedimentos Endovasculares , Aneurisma Intracraniano , Humanos , Procedimentos Endovasculares/efeitos adversos , Procedimentos Endovasculares/métodos , Aneurisma Intracraniano/cirurgia , Anestesia Local/métodosRESUMO
BACKGROUND: Local anesthetic puncture is often related to the experience of pain. This study aimed to systematically analyze the literature on changes in pain perception during the anesthetic puncture of dental local anesthesia after Photobiomodulation Therapy (PBMT). MATERIAL AND METHODS: An electronic search was performed in eight primary databases (Embase, LILACS, BBO, LIVIVO, MedLine via PubMed, SciELO, Scopus, and Web of Science) and three additional ones (EASY, Google Scholar, and OATD) to partially capture the "gray literature". The PICO strategy was used to identify randomized clinical trials evaluating the analgesic effect of PBMT in the anesthetic puncture site of dental local anesthesia compared to placebo or control groups, without restrictions on publication language and year. Two reviewers extracted the data and assessed the individual risk of bias of the eligible studies using the Cochrane Collaboration Risk of Bias Tool version 2.0. RESULTS: The electronic search found 3,485 records, of which eight met the eligibility criteria and were included in the qualitative synthesis. The studies were published from 2011 to 2022. None of the included studies had a low risk of bias. PBMT groups showed no significant difference in pain scores compared to placebo and control groups of most studies. CONCLUSION: Based on a low to very low certainty of evidence, PBMT seems to have no effect on pain perception during anesthetic puncture in patients undergoing dental local anesthesia.
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Anestesia Dentária , Anestesia Local , Terapia com Luz de Baixa Intensidade , Percepção da Dor , Humanos , Terapia com Luz de Baixa Intensidade/métodos , Percepção da Dor/fisiologia , Percepção da Dor/efeitos da radiação , Anestesia Local/métodos , Anestesia Dentária/métodos , Medição da Dor , Punções/efeitos adversos , Ensaios Clínicos Controlados Aleatórios como Assunto , Dor Processual/prevenção & controle , Dor Processual/etiologia , Dor Processual/terapiaRESUMO
INTRODUCTION: Thyroidectomy is a common surgical procedure. Traditional options for pain management, such as analgesics and nonsteroidal anti-inflammatory medications (NSAIDs), are limited by their side effects. Surgical wound infiltration with local anesthetics has the potential to reduce the need for analgesics in a number of surgical procedures. This systematic review and meta-analysis wanted to resolve these concerns and assess the efficacy of WI in the management of postoperative pain after thyroidectomy. MATERIAL AND METHODS: The review adhered to Cochrane Collaboration and PRISMA standards. RCTs comparing WI with no infiltration or placebo were included. Patients with benign or malignant thyroid disease who underwent open thyroidectomy were eligible. Postoperative pain was assessed using a visual analogue scale (VAS) as the primary outcome. Time to first rescue dose, the need for analgesic rescue in the first 24 h, and total opioid analgesic consumption were secondary outcomes. Standardized mean difference (SMD) and odds ratio (OR) were used to analyze the data. RESULTS: 16 randomized controlled trials involving 1202 patients were included. At 6 and 8 h postoperatively, WI exhibited a statistically significant impact on pain management. In the WI group, the need for analgesic rescue was significantly reduced. At 4 h postoperatively, non-anesthetic medications demonstrated a significant analgesic effect. CONCLUSIONS: This systematic review and meta-analysis support the use of WI with local anesthetics for postoperative pain management after thyroidectomy. These findings have significant implications for improving perioperative care, especially in ambulatory settings where effective pain management is essential.
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Anestésicos Locais , Dor Pós-Operatória , Ensaios Clínicos Controlados Aleatórios como Assunto , Tireoidectomia , Humanos , Tireoidectomia/efeitos adversos , Dor Pós-Operatória/tratamento farmacológico , Anestésicos Locais/administração & dosagem , Manejo da Dor/métodos , Medição da Dor , Anestesia LocalRESUMO
PURPOSE: The aim of this study was to compare the analgesic efficacy of 4% articaine associated with epinephrine (1:100,000), and 2% lidocaine associated with epinephrine (1:100,000) in third molar extraction surgery. METHODS: Sixty patients who underwent surgeries to extract upper and lower third molars were included in this split-mouth, double-blind, randomized, controlled trial. The groups in this study were divided according to the anesthetic solution used to provide local anesthesia during extraction of upper and lower third molars: (1) 4% articaine associated with epinephrine (1:100,000); (2) 2% lidocaine associated with epinephrine (1:100,000). The time to the beginning and end of the sensation of analgesia, pain sensation according to the VAS scale, and number of anesthetic tubes necessary for supplementation were analyzed. RESULTS: It was found that the onset time for analgesia was shorter on the side anesthetized with articaine compared to the side anesthetized with lidocaine (122.1 ± 52.90 s vs. 144.5 ± 68.85 s) (p < 0.05). In addition, the number of tubes used for anesthetic supplementation was also reduced on the articaine side compared to the lidocaine side (0.26 ± 0.48 vs. 0.50 ± 0.75) (p < 0.05). There were no differences between the anesthetic solutions in the other evaluated parameters. CONCLUSION: It can be concluded that the use of 4% articaine associated with epinephrine (1:100,000) reduced the time of onset of analgesia and the necessity for anesthetic supplementation in third molar extraction surgeries compared to the use of 2% lidocaine associated with epinephrine (1:100,000).
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Anestésicos Locais , Carticaína , Epinefrina , Lidocaína , Dente Serotino , Dor Pós-Operatória , Extração Dentária , Humanos , Carticaína/administração & dosagem , Dente Serotino/cirurgia , Lidocaína/administração & dosagem , Método Duplo-Cego , Masculino , Anestésicos Locais/administração & dosagem , Feminino , Adulto , Epinefrina/administração & dosagem , Dor Pós-Operatória/prevenção & controle , Dor Pós-Operatória/tratamento farmacológico , Adulto Jovem , Medição da Dor , Anestesia Dentária/métodos , Adolescente , Anestesia Local/métodosRESUMO
INTRODUCTION: This study aimed to assess the learning curves of peribulbar anesthesia and estimate the number of blocks needed to attain proficiency. METHODS: Anonymized records of sequential peribulbar blocks performed by first-year anesthesia residents were analyzed. The block sequential number and the outcomes were extracted from each record. Success was defined as a complete sensory and motor block of the eye, and failure was defined as an incomplete block requiring supplemental local anesthetic injections or general anesthesia. Learning curves using the LC-CUSUM method were constructed, aiming for acceptable and unacceptable failure rates of 10% and 20%, and 10% probability of type I and II errors. Simulations were used to determine the proficiency limit h0. Residents whose curves reached h0 were considered proficient. The Sequential Probability Ratio Test Cumulative Sum Method (SPRT-CUSUM) was used for follow-up. RESULTS: Thirty-nine residents performed 2076 blocks (median = 52 blocks per resident; Interquartile Range (IQR) [range] = 27-78 [4-132]). Thirty residents (77%) achieved proficiency after a median of 13 blocks (13-24 [13-24]). CONCLUSIONS: The LC-CUSUM is a robust method for detecting resident proficiency at peribulbar anesthesia, defined as success rates exceeding 90%. Accordingly, 13 to 24 supervised double-injection peribulbar blocks are needed to attain competence at peribulbar anesthesia.
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Anestesiologia , Internato e Residência , Humanos , Curva de Aprendizado , Competência Clínica , Anestesiologia/educação , Anestesia LocalRESUMO
BACKGROUND: Forehead aesthetic injections are a well-known source of discomfort, and many analgesic non-invasive techniques have been proposed to ameliorate pain. However, no study has compared all these techniques for aesthetic purposes. Therefore, this study aimed to compare the effectiveness of topical cream anesthesia, vibratory stimulus, cryotherapy, pressure, and even no intervention, on pain during and immediately after injection, when considering aesthetic injections in the forehead. METHODS: Seventy patients were selected and had their foreheads divided into 5 parts, which received four different analgesic techniques, and one control zone was added. A numeric rating scale was used to assess pain, two direct questions were asked to evaluate patients' preference and discomfort with the techniques, and the adverse events were quantified. The injections were performed in the same sequence, with three minutes of rest between them and in a single session. Comparisons among analgesic methods for pain relief were performed by the one-way analysis of variance (ANOVA), considering a significance level of 5%. RESULTS: No significant differences were found among the analgesic methods, and between the methods and the control zone, both during and immediately after the injections (p > 0.05). The preferred method for pain relief was the use of topical anesthetic cream (47%), while the most uncomfortable technique was manual distraction (pressure) (36%). Only one patient reported an adverse event. CONCLUSIONS: No analgesic method to diminish pain was superior to the others or was better than no method. Nevertheless, the topical anesthetic cream was the preferred technique, causing less discomfort. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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Anestésicos Locais , Dor , Humanos , Anestesia Local , Músculo Esquelético , AnalgésicosRESUMO
Introducción: La técnica de anestesia local con epinefrina sin el uso de manguito hemostático (Wide Awake Local Anesthesia - No Tourniquet, WALANT) se desarrolló para mejorar el acceso a la atención de la cirugía de mano y optimizar recursos médicos. El principal objetivo de este estudio fue evaluar la experiencia del paciente y analizar el ahorro de costos hospitalarios en el tratamiento quirúrgico de descompresión del síndrome del túnel carpiano utilizando esta técnica anestésica. Materiales y Métodos: Se realizó un estudio descriptivo prospectivo observacional en pacientes con diagnóstico clínico de síndrome del túnel carpiano operados entre 2016 y 2022. El grado de satisfacción del paciente fue evaluado mediante un cuestionario sobre el dolor en diferentes momentos, la ansiedad y la experiencia con el procedimiento. También se analizaron los costos de la técnica anestésica. Resultados: Se evaluó a 92 pacientes. La mayoría se mostró satisfecha y el 94,5% confirmó que volvería a elegir este procedimiento, los niveles de dolor y ansiedad fueron bajos. Se registró un ahorro de costos del 60,6% por procedimiento. Conclusiones: La descompresión del síndrome del túnel carpiano con técnica WALANT generó un ahorro de costos considerable para el sistema de salud nacional, los resultados fueron buenos sobre la base de la satisfacción, la ansiedad y el dolor; y es un procedimiento seguro, cómodo y eficiente. Los beneficios y su rentabilidad al emplear menos recursos hospitalarios podrían ser optimizados y reproducidos para generar un ahorro considerable en gastos de salud. Nivel de Evidencia: IV
Introduction: Wide-awake local anesthesia no tourniquet (WALANT) is an anesthetic technique that was developed to improve patient access to treatment and optimize the use of available medical resources in hand surgery. The main purpose of this study was to evaluate patient experience and hospital cost savings during surgical treatment of carpal tunnel syndrome (CTS) with this technique at a South American public hospital. Materials and Methods: Between 2016 and 2022, a descriptive prospective observational study was conducted on patients with a clinical diagnosis of CTS who had undergone surgical treatment. Patient satisfaction was assessed using a questionnaire that asked about pain during different periods of time, anxiety, and the procedure itself. The costs of the anesthetic technique were also analyzed. Results: 92 patients were evaluated and the majority of them were satisfied with their WALANT experience; 94.5% said they would choose this procedure again, citing low levels of pain and anxiety. A cost reduction of 60.6% per procedure was achieved. Conclusions: CTS decompression with the WALANT technique resulted in significant cost savings for the national health system, as well as favorable outcomes in terms of satisfaction, anxiety, and pain; the procedure was safe, comfortable, and efficient. The benefits and profitability of employing fewer hospital resources could be further optimized and replicated to result in significant health-care cost savings. Level of Evidence: IV
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Adulto , Pessoa de Meia-Idade , Idoso , Síndrome do Túnel Carpal , Satisfação do Paciente , Mãos , Anestesia LocalRESUMO
Abstract Objective To compare patients undergoing total knee arthroplasty (TKA) under spinal anesthesia and single femoral nerve block (FNB) with subjects undergoing TKA under spinal anesthesia and periarticular infiltration (PAI). Materials and Methods A total of 100 patients undergoing primary TKA were randomized into two groups. Group 1 included patients undergoing surgery under FNB associated with spinal anesthesia, while group 2 included patients undergoing TKA under IPA and spinal anesthesia. The assessment of these subjects in the early postoperative period included pain, active flexion, active extension, elevation of the extended limb, and morphine use. Results There was no significant difference in the types of analgesia concerning pain, the elevation of the extended limb, and morphine use. Active flexion and extension were better in the PAI group (p = 0.04 and p = 0.02 respectively). Conclusion We conclude that the techniques are similar regarding pain control, limb elevation, and morphine use. The use of IPA provided better active flexion and extension during the hospital stay compared to single FNB in patients undergoing TKA.
Resumo Objetivo Avaliar pacientes submetidos a artroplastia total do joelho (ATJ) sob raquianestesia e bloqueio do nervo femoral (BNF) único e comparar com pacientes que submetidos a ATJ sob raquianestesia e infiltração periarticular (IPA). Materiais e Métodos Um total de 100 pacientes submetidos a ATJ foram randomizados em dois grupos. O grupo 1 incluiu pacientes submetidos a ATJ sob BNF associado à raquianestesia, ao passo que o grupo 2 incluiu pacientes submetidos a ATJ sob IPA associada à raquianestesia. Os indivíduos foram avaliados no pós-operatório precoce quanto à dor, à flexão e extensão ativas, à elevação do membro estendido e ao uso de morfina. Resultados Não se observou diferença significativa associada ao tipo de analgesia em relação à dor, à elevação do membro em extensão e ao consumo de morfina. Houve melhor flexão e extensão ativas no grupo que recebeu IPA (p = 0,04 e p = 0,02, respectivamente). Conclusão Concluímos que as técnicas utilizadas são semelhantes quanto ao controle da dor, à elevação de membro e ao uso de morfina. O uso de IPA proporcionou uma melhor flexão e extensão ativas durante o período de internação hospitalar comparado ao uso de BNF único em pacientes submetidos a ATJ.
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Humanos , Artroplastia do Joelho , Nervo Femoral , Analgesia , Anestesia Local , Bloqueio NervosoRESUMO
Objetivo:Revisar sistematicamente a literatura sobre a efetividade do método computadorizado de anestesia odontológica em relação àdor, comportamento não colaborador e o medo/ansiedade em crianças e adolescentes em comparação com o método convencional. Materiais e métodos:Uma buscaeletrônica foi realizada em cinco base de dados (Biblioteca Virtual em Saúde, Scopus, Embase, Pubmed e Web of Science)e que incluiu ensaios clínicos randomizados. A busca foi realizada em outubro de 2020 eatualizada em maio de 2021 e, não houve restrição de data ou idioma. A avaliação de risco de viés foi realizada usando aRoB 2 e, tambémfoi realizada uma análise qualitativa. Resultados:Foram encontrados 3.518 estudos, e após a remoção das duplicatas, análise do título e resumo e,leitura completa, restaram 26 estudos incluídos. Destes,cinco avaliaram ansiedade/medo, doze avaliaram o comportamento durante a anestesia, e vinte e dois avaliaram a percepção de dor. Não foi observadodiferença significativa na maioria dos estudos entreo uso do método computadorizado em comparação ao método tradicionalpara todos os desfechos analisados. Discussão:Apesar de não parecer haver diferença significativa na percepção de dor, no relato de medo/ansiedade e no comportamento entre o uso do método computadorizado emcomparação ao método tradicional, é fundamentalavaliar o comportamento da criança durante o atendimento odontológico pois suas expressões podem indicar algum desconforto e dor. Esses achados devem ser interpretados com cautela, considerando que quase três quartos dos estudos incluídos apresentaram alto risco de viés. Conclusão:Mesmo com a ausência de diferença, os dispositivos eletrônicos são promissores, visto que promovem uma administração lenta e controlada e resultam em uma anestesia segura e eficaz que coloca-se como alternativa a prática clínica.
Aim:To systematically review the literature on the effectiveness of the computerized method of dental anesthesia in relation to pain, non-collaborative behavior and fear/anxiety in children and adolescents compared to the conventional method. Materials and methods:An electronic search was performed in five databases (Virtual Health Library, Scopus, Embase, Pubmed and Web of Science)that included randomized clinicaltrials. The search was performed in October 2020 and updated in May 2021. The risk of bias assessment was performed using the RoB 2 andaqualitative analysis was also performed. Results:A total of 3,518 studieswere found, and after removing duplicates, analyzing the title and abstract, and completereading, 26 studies remainedincluded. Of these, five assessed anxiety/fear, twelve assessed behavior during anesthesia, and twenty-two assessed pain perception. No significant difference was observed in most studies between the use of the computerized method compared to the traditional method for all outcomesanalyzed. Discussion:Although there does not seem tobe a significant difference in pain perception, fear/anxiety reports and behavior between the use of the computerized method and the traditional method, it is fundamental to evaluate the child's behavior during dental care, as their expressions may indicate some discomfort and pain. These findings should be interpreted with caution, considering that nearly three-quarters of the included studies were at high risk of bias. Conclusion:Even with the absence of difference, electronic devices are promising, as they promote slow and controlled administration and result in safe and effective anesthesia, which is an alternative to clinical practice.
Assuntos
Pré-Escolar , Criança , Adolescente , Anestesia Local , Ensaios Clínicos Controlados Aleatórios como AssuntoRESUMO
Objetivo: Dificuldades anestésicas podem decorrer de cenários de infecção e inflamação, como são os casos de pulpite irreversível. Logo, o propósitoda presente revisãosistematizadafoiauxiliar o clínico a alcançar anestesia profunda durante o tratamento de urgência endodôntica de molares mandibulares com pulpite irreversível. Materiais e métodos:Foram selecionados viaPubMed,ensaios clínicos randomizadosrealizados compacientes com pulpite irreversível em molares mandibulares procurando atendimento de urgência. Estes deveriam avaliaro sucesso anestésico através do relato de dor duranteaabertura coronária e/ou instrumentação dos canais radiculares. Dois desfechos primários distintos eram alvo deste estudo (soluções anestésicas e condutas alternativas). Para soluções anestésicas, foram incluídos 18 estudos, e para condutas alternativas, 10 estudos.Revisão de literatura: Diversas estratégias têm sido investigadas para aumentar o percentual de sucesso anestésico, como ouso de técnicas complementares ao bloqueio do nervo alveolar inferior (BNAI), o aumento do volume de anestésico ou do vasoconstritor, o tamponamento das soluções econdutas alternativas.Discussão: Constatou-seque não há diferença na taxa de sucesso no BNAI e para técnicas anestésicas complementares para os diferentes agentes anestésicos. Além disso, a maior concentração de adrenalina, o aumento do volume da solução utilizada, substâncias capazes detamponar a solução anestésica, a administração ou injeção de anti-inflamatórios, a crioterapia e o óxido nitroso também parecem melhoram as taxas de sucesso anestésico.Conclusão:Diversos métodos alternativos parecem promissores para potencializar uma anestesia profunda, e devem ser mais bem investigados para a adoção de parâmetros em prol de seu emprego definitivo.
Aim:Anesthetic difficulties may arise from scenarios of infection and inflammation, as in cases of irreversible pulpitis. Therefore, the purpose of this systematized review was to help the clinician to achieve deep anesthesia during emergency endodontic treatment of mandibular molars with irreversible pulpitis. Materials and methods:Randomized clinical trials performed with patients with irreversible pulpitis in mandibular molars seeking emergency care were selected via PubMed. These should assess anesthetic success by reporting pain during coronary opening and/or instrumentation of root canals. Two distinct primary outcomes were the target of this study (anesthetic solutions and alternative approaches). For anesthetic solutions, 18 studies were included, and for alternative conducts, 10 studies. Literature review:Several strategies have been investigated to increase the percentage of anesthetic success, such as the use of complementary techniques to inferior alveolar nerve block (IANB), increasing the volume of anesthetic or vasoconstrictor, tamponade of solutions and alternative approaches. Discussion:It was found that there is no difference in the success rate for the IANB and for complementary anesthetic techniques for the different anesthetic agents. In addition, higher adrenaline concentration, increased volume of solution used, substances capable of buffering the anesthetic solution, administration or injection of anti-inflammatories, cryotherapy and nitrous oxide also seem to improve anesthetic success rates. Conclusion:Several alternative methods seem promising to potentiate deep anesthesia, and should be better investigated for the adoption of parameters in favor of its definitive use.
Assuntos
Pulpite , Anestesia Dentária , Anestesia Local , Carticaína , Ensaios Clínicos Controlados Aleatórios como Assunto , Revisão , Lidocaína , MepivacaínaRESUMO
This crossover study aimed to compare the anesthetic effects of buffered 2% articaine with 1:200,000 epinephrine with that of non-buffered 4% articaine with 1:200,000 epinephrine. Forty-seven volunteers were administered two doses of anesthesia in the buccal region of the second mandibular molars in two sessions using 1.8 mL of different local anesthetic solutions. The onset time and duration of pulp anesthesia, soft tissue pressure pain threshold, and the score of pain on puncture and burning during injection were evaluated. The operator, volunteers, and statistician were blinded. There were no significant differences in the parameters: onset of soft tissue anesthesia (p = 0.80), duration of soft tissue anesthesia (p = 0.10), onset of pulpal anesthesia in the second (p = 0.28) and first molars (p = 0.45), duration of pulp anesthesia of the second (p = 0.60) and first molars (p = 0.30), pain during puncture (p = 0.82) and injection (p = 0.80). No significant adverse events were observed. Buffered 2% articaine with 1:200,000 epinephrine did not differ from non-buffered 4% articaine with 1:200,000 epinephrine considering anesthetic success, safety, onset, duration of anesthesia, and pain on injection.
Assuntos
Carticaína , Lidocaína , Humanos , Carticaína/farmacologia , Lidocaína/farmacologia , Estudos Cross-Over , Anestésicos Locais/farmacologia , Epinefrina/farmacologia , Anestesia Local , Dor , Dente Molar , Método Duplo-CegoRESUMO
Abstract Background: Ultra-low-dose Spinal Anesthesia (SA) is the practice of employing minimal doses of intrathecal agents so that only the roots that supply a specific area are anesthetized. The aim of this study was to compare the effectiveness and safety of ultra-low-dose spinal anesthesia with that of Perineal Blocks (PB). Methods: A two-arm, parallel, double-blind randomized controlled trial comparing two anesthetic techniques (SA and PB) for hemorrhoidectomy and anal fistula surgery was performed. The primary outcomes were postoperative pain, complementation and/or conversion of anesthesia, and hemodynamic changes. Results: Fifty-nine patients were included in the final analysis. The mean pain values were similar in the first 48 h in both groups (p > 0.05). The individuals allocated to the SA group did not need anesthetic complementation; however, those in the PB group required it considerably (SA group, 0% vs. PB group, 25%; p = 0.005). Hemodynamic changes were more pronounced after PB: during all surgical times, the PB group showed lower MAP values and higher HR values (p < 0.05). Postoperative urinary retention rates were similar between both groups (SA group 0% vs. PB group 3.1%, p = 0.354). Conclusion: SA and PB are similarly effective in pain control during the first 48 h after hemorrhoidec-tomy and anal fistula surgery. Although surgical time was shorter among patients in the PB group, the SA technique may be preferable as it avoids the need for additional anesthesia. Furthermore, the group that received perineal blocks was under sedation with a considerable dose of propofol.
Assuntos
Humanos , Fístula Retal/cirurgia , Raquianestesia/métodos , Anestésicos , Dor Pós-Operatória/prevenção & controle , Anestesia LocalRESUMO
Objectives: To evaluate the effect of pressure on the skin of upper lip in decreasing pain perception during a local maxillary anesthetic injection. Material and Methods: A split-mouth crossover randomized clinical trial was designed. Seventy-one volunteer students (23.6±1.9 years old, 53.5% women) were selected. A group chosen at random had their left or right side of upper lip compressed by a wooden clothes peg as the compression instrument and 0.6 ml of lidocaine 2% with epinephrine 1:100,000 was administered at the buccal apex level of the lateral incisors tooth. Two weeks later anesthesia was administered on the opposite side of the lip according to the randomization recorded. The intensity of perceived pain level between the two injections using a 100 mm visual analog scale (VAS) and co-variable effect were compared (Wilcoxon test p < 0.05, RStudio). Results: The average of the perceived pain with and without upper lip compression was 27.6±14.5 mm (range 0-80 mm) and 36.33±17.9 mm (range 10-90 mm) respectively (p= 0.002). No significant differences were recorded according the covariance analysis with the sex (p = 0.55) and age (p = 0.89). Conclusion: The upper lip compression significantly reduces the perception of pain during a local maxillary anesthetic technique.
Assuntos
Humanos , Masculino , Feminino , Adulto , Dor , Anestesia Local , Lábio , Boca , Ensaio Clínico Controlado AleatórioRESUMO
PURPOSE: The primary objective of this study was to compare the WALANT (wide awake, local anesthesia, no tourniquet) technique with local anesthesia associated with sedation in relation to pain intensity for minor hand surgical procedures. The secondary objective was to evaluate the need for analgesic complementation. METHODS: A prospective, randomized, comparative, and clinical study was carried out. The sample size in each group was determined after statistical evaluation of the results of a pilot project. The participants were allocated to one of two groups; those in group 1 were submitted to the WALANT technique, and those in group 2, to local anesthesia associated with sedation, for elective surgery. The surgical procedures were carpal tunnel syndrome, De Quervain's tenosynovitis, synovial cyst, finger cyst, and trigger finger. Pain intensity, need for complementation and evolution to complex regional pain syndrome were evaluated. RESULTS: There was no difference between groups in pain intensity after WALANT and need for intraoperative complementation. There was no significant difference in the amount of opioid applied postoperatively between the groups. There was no difference between groups regarding comfort during surgery. There was no difference in adverse effects and complications between the groups. Hematoma was the most frequent adverse event. No severe adverse events were observed. CONCLUSIONS: The WALANT technique promoted an analgesic effect similar to that of local anesthesia associated with sedation, without increasing adverse effects.
Assuntos
Anestesia Local , Síndrome do Túnel Carpal , Humanos , Anestesia Local/métodos , Mãos/cirurgia , Estudos Prospectivos , Projetos Piloto , Síndrome do Túnel Carpal/cirurgiaRESUMO
Abstract Objective The present study compares the analgesic efficacy of two techniques to perform non-surgical reduction: fracture hematoma block and radial nerve supracondylar block. Methods Forty patients with fractures of the distal third of the radius, who required reduction, were selected in a quasi-randomized clinical trial to receive one of the anesthetic techniques. All patients signed the informed consent form, except for those who did not wish to participate in the study, had neurological injury, had contraindication to the procedure in the emergency room, or with contraindication to the use of lidocaine. To measure analgesia, the numerical pain rate scale was used at four different moments: preblock, postblock, during reduction, and after reduction; then three differences were calculated: the first between before and after blocking; the second between during reduction and after blockade; and the third between before blocking and after reduction. Results The fracture hematoma and supracondylar block groups showed the following mean values, respectively: 3.90 (1-10) and 3.50 (-6-10) in difference 1; 4.35 (-5-10) and 5.00 (-3-10) in difference 2; and 4.65 (1-10) and 3.80 (-3-10) in difference 3. Conclusion Both techniques proved to be efficient for analgesia, with mild superiority of hematoma block, but without statistical significance.
Resumo Objetivo O estudo compara a eficácia analgésica de duas técnicas para realizar redução incruenta: o bloqueio de hematoma da fratura e o bloqueio supracondilar de nervo radial. Métodos Quarenta pacientes com fraturas do terço distal do rádio, que necessitassem redução, foram selecionados em um ensaio clínico quasi-randomizado, para receber uma das técnicas anestésicas. Todos os pacientes assinaram o termo de consentimento ou assentimento, com exceção daqueles que não desejassem participar do estudo, tivessem lesão neurológica, com contraindicação ao procedimento na sala de emergências, ou com contraindicação ao uso da lidocaína. Para aferir a analgesia foi utilizada a escala numérica da dor em quatro momentos distintos: pré-bloqueio, pós-bloqueio, durante a redução e após a redução; em seguida, foram calculadas três diferenças: a primeira entre antes e após o bloqueio; a segunda entre durante a redução e após o bloqueio; e a terceira entre antes do bloqueio e após a redução. Resultados Os grupos do bloqueio de hematoma de fratura e bloqueio supracondilar apresentaram respectivamente os seguintes valores médios: 3.90 (1-10) e 3.50 (-6-10) na diferença 1; 4.35 (-5-10) e 5.00 (-3-10) na diferença 2; e 4.65 (1-10) e 3.80 (-3-10) na diferença 3. Conclusão As duas técnicas se provaram eficientes para analgesia, com discreta superioridade do bloqueio de hematoma, mas sem significância estatística.