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1.
Vet Clin North Am Exot Anim Pract ; 22(3): 539-548, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31395330

RESUMO

In recent years, there has been a dramatic change in how information can be disseminated in the scientific world. This is especially true for health care in general, and exotic pet practice hardly makes an exception. From the constant growth of online repositories that archives scholarly articles such as PubMed, to the creation of hashtags specific for health care that can be followed by millions of persons, we need to understand that communication is changing and that the proper use of modern technologies may result in an unprecedented era for knowledge retrieval and dissemination.


Assuntos
Animais Exóticos , Disseminação de Informação/métodos , Medicina Veterinária/métodos , Animais , Bases de Dados Bibliográficas , MEDLINE , Revisão por Pares , PubMed , Ferramenta de Busca , Mídias Sociais
2.
Yakugaku Zasshi ; 139(7): 1027-1046, 2019.
Artigo em Japonês | MEDLINE | ID: mdl-31257250

RESUMO

The application of systematic review (SR) has been increased rapidly in the field of cancer treatment. Complementary and alternative medicine (CAM) for cancer is no exception. The aim of this review is to evaluate and summarize systematic reviews on the CAM use in breast cancer patients. Search sources were Centre for Reviews and Dissemination (CRD), Cochrane Database of Systematic Reviews (CDSR), and PubMed. In addition, we assessed the quality of SR with the Assessing the Methodological Quality of Systematic Reviews (AMSTAR). This review did not consider control groups and outcomes. Thirty-four SRs met a set of criteria. According to interventions, there were twenty SRs which included yoga, acupuncture, and herbal medicines. Meta-analysis of 19 out of 34 reviews showed the followings: (1) acupuncture had a beneficial effect on the frequency of hot flushes, (2) yoga had a beneficial effect on depression and health-related QOL, (3) mindfulness-based stress reduction (MBSR) had a beneficial effect on anxiety and depression, (4) combination of herbal medicine and chemotherapy synergistically improved clinical outcomes, (5) acupuncture did not show significant effect on the severity of hot flushes and cancer-related pain, (6) yoga was unable to be confirmed as having an effect on cancer-related pain and physical well-being. Given the results of AMSTAR, 9 out of 34 reviews were of high quality and 3 reviews were deemed to be of low quality. In conclusion, since most SRs were at moderate or high quality levels, CAM could be helpful for treating specific symptoms related to breast cancer.


Assuntos
Neoplasias da Mama/terapia , Terapias Complementares , Terapia por Acupuntura , Ansiedade , Neoplasias da Mama/psicologia , Bases de Dados Bibliográficas , Depressão , Feminino , Medicina Herbária , Humanos , Atenção Plena , Cuidados Paliativos , Qualidade de Vida , Ioga
3.
Rev Assoc Med Bras (1992) ; 65(5): 682-690, 2019 Jun 03.
Artigo em Inglês | MEDLINE | ID: mdl-31166446

RESUMO

BACKGROUND.: This study aimed to evaluate the scientific production of researchers in the field of Medicine who receive a productivity grant from the CNPq. METHODS: The curriculum Lattes of 542 researchers with active grants from 2012 to 2014 were included in the analysis. Grants categories/levels were stratified into three groups according to the CNPq database (1A-B, 1C-D, and 2). RESULTS.: There was a predominance of grants in category 2. During their academic career, Medicine researchers published 76512 articles, with a median of 119 articles per researcher (IQ, interquartile range, 77 to 174). Among the 76512 articles, 36584 (47.8%) were indexed in the Web of Science (WoS database). Researchers in Medicine were cited 643159 times in the WoS database, with a median of 754 citations (IQ, 356 to 1447). There were significant differences among the categories of grants concerning the number of citations in WoS (P <0.001). There was a significant difference in the number of times researchers were cited according to the specialty included in Medicine area. (P < 0.001). CONCLUSION.: Strategies to improve the scientific output qualitatively possibly can be enhanced by the knowledge of the profile of researchers in the field of Medicine.


Assuntos
Bibliometria , Pesquisa Biomédica/estatística & dados numéricos , Pesquisadores/estatística & dados numéricos , Apoio à Pesquisa como Assunto/estatística & dados numéricos , Brasil , Estudos Transversais , Bases de Dados Bibliográficas/estatística & dados numéricos , Organização do Financiamento , Órgãos Governamentais , Humanos , Publicações Periódicas como Assunto/estatística & dados numéricos , Distribuição por Sexo , Fatores de Tempo
4.
Distúrb. comun ; 31(2): 261-269, jun. 2019. ilus
Artigo em Português | LILACS | ID: biblio-1008214

RESUMO

Introdução: A asma e a rinite alérgica têm sido consideradas manifestações de uma mesma síndrome, uma vez que apresentam bases epidemiológicas, genéticas e fisiopatológicas comuns. A interação entre a dificuldade na função de respiração, a asma e a rinite alérgica podem promover alterações no sistema estomatognático, como as funções de mastigação e a deglutição, além de modificações anatômicas e funcionais, no crescimento facial e somático. Objetivo: Realizar uma revisão integrativa da avaliação da mastigação e deglutição em crianças e adolescentes com rinite e asma. Materiais e Métodos: Foi realizada uma pesquisa nas bases de dados Lilacs, MedLine, PubMed e Scielo, sobre artigos que abordavam a deglutição e mastigação em crianças e adolescentes com asma e rinite no período de janeiro e fevereiro de 2017, e a pesquisa foi atualizada em junho de 2018. Resultados: Foram encontrados 2.537 artigos, mas apenas cinco apresentaram os critérios de elegibilidade. Discussão: Poucos estudos referentes ao tema foram encontrados. Dos cinco artigos selecionados, três inferiram não encontrar alterações e dois encontraram padrões alterados, relacionando com o fator de obstrução nasal. É necessário que mais pesquisas sejam realizadas sobre o tema. Conclusão: Não há evidências científicas que afirmem a presença de alterações de mastigação e deglutição decorrentes da asma e da rinite em crianças e adolescentes.


Introduction: Asthma and allergic rhinitis have been considered as manifestations of the same syndrome, since they have common epidemiological, genetic and pathophysiological bases. The interaction between difficulty in breathing function, asthma and allergic rhinitis may promote changes in the stomatognathic system, such as chewing and swallowing functions, as well as anatomical and functional changes in facial and somatic growth. Objective: To perform an integrative review of chewing and swallowing assessment in children and teenagers with rhinitis and asthma. Materials and Methods: We searched the Lilacs, MedLine, PubMed and Scielo databases for articles on swallowing and chewing in children and teenagers with asthma and rhinitis in January and February 2017, and this research was updated in June 2018. Results: A total of 2,537 articles were found, but only five presented the eligibility criteria. Discussion: Few studies regarding the topic were found. Of the five articles selected, three inferred to find no alterations and two found altered patterns, relating to the nasal obstruction factor. More research is needed on the subject. Conclusion: There is no scientific evidence to support the presence of chewing and swallowing disorders due to asthma and rhinitis in children and teenagers.


Introducción: El asma y la rinitis alérgica se han considerado manifestaciones de un mismo síndrome, ya que presentan bases epidemiológicas, genéticas y fisiopatológicas comunes. La interacción entre la dificultad en la función de respiración, el asma y la rinitis alérgica pueden promover alteraciones en el sistema estomatognático, como las funciones de masticación y deglución, además de modificaciones anatómicas y funcionales, en el crecimiento facial y somático. Objetivo: Realizar una revisión integrativa de la evaluación de la masticación y deglución en niños y adolescentes con rinitis y asma. Materiales y Métodos: Se realizó una investigación en las bases de datos Lilacs, MedLine, PubMed y Scielo, sobre artículos que abordaban la deglución y masticación en niños y adolescentes con asma y rinitis en el período de enero y febrero de 2017, la investigación fue actualizada en junio de 2018. Resultados: Se encontraron 2.537 artículos, pero sólo cinco presentaron los criterios de elegibilidad. Discusión: Pocos estudios referentes al tema fueron encontrados. De los cinco artículos seleccionados, tres dedujeron no encontrar alteraciones y dos encontraron patrones alterados, relacionando con el factor de obstrucción nasal. Es necesario que más investigaciones se realicen sobre el tema. Conclusión: No hay evidencias científicas que afirmen la presencia de alteraciones de masticación y deglución derivadas del asma y de la rinitis en niños y adolescentes.


Assuntos
Humanos , Criança , Adolescente , Asma , Bases de Dados Bibliográficas , Deglutição , Fonoaudiologia , Rinite Alérgica , Mastigação
5.
Diagn. tratamento ; 24(2): [59-63], abr - jun 2019. tab, fig
Artigo em Português | LILACS | ID: biblio-1015338

RESUMO

Introdução: Com o crescimento contínuo das informações disponíveis na área da saúde, é fundamental que o profissional da saúde desenvolva habilidades e competências para realizar buscas de evidências cientificas. Objetivo: Apresentar as principais bases da área da saúde e os mecanismos de busca específicos para cada uma delas. Métodos: Estudo descritivo desenvolvido na Disciplina de Medicina Baseada em Evidências da Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (Unifesp). Resultados: Este estudo apresentou os quatro passos do processo de busca em uma base de dados científica da área da saúde: (1) identificação da pergunta estruturada por meio dos acrônimos PICO/PECO, (2) escolha da base de dados (3) escolha e uso dos descritores em saúde apropriados para cada base (DeCS/MeSH/EMTREE) e (4) escolha e uso dos operadores booleanos (AND/OR/AND NOT). Conclusão: O processo de elaboração de uma estratégia de busca para bases de dados da área da saúde pode ser estruturado em quatro passos iniciais, que vão da identificação da pergunta estruturada ao uso dos operadores booleanos. Apropriar-se destes passos é fundamental para conseguir elaborar uma estratégia de busca adequada, capaz de recuperar os estudos de interesse e que abordem realmente a pergunta proposta.


Assuntos
Epidemiologia Descritiva , Bases de Dados Bibliográficas , Medicina Baseada em Evidências , Medical Subject Headings , Metodologia , Ferramenta de Busca
6.
Recurso educacional aberto em Espanhol | CVSP - Regional | ID: oer-3844

RESUMO

Al final de este guía, el usuario es capaz de: - Acceder el sistema FI-Admin para ingresar y editar registros de recursos educativos de un repositorio del nodo país del CVSP. - Reconocer los principales componentes y funciones del sistema FI-Admin, permitiendo describir, indizar, enlazar y relacionar los registros de recursos educativos.


Assuntos
Materiais de Ensino , Bases de Dados Bibliográficas , Bibliotecas Digitais , Catalogação , Resumos e Indexação como Assunto , Gestão da Informação , Sistemas de Informação
7.
Zhongguo Zhong Yao Za Zhi ; 44(8): 1674-1681, 2019 Apr.
Artigo em Chinês | MEDLINE | ID: mdl-31090334

RESUMO

As a new concept in clinical research,the real world research(RWR) has attracted the attention of researchers in the world with its unique advantages. This research mainly analyzed it through visual methods,the specific steps were as follows. Firstly,the Chinese Biomedical Literature Database,China National Knowledge Infrastructure,Wan Fang Database,Medline and EMbase were searched and RWS were included,414 articles in Chinese and 2 158 articles in English were included in this research after layer-bylayer screening; secondly,the main information was extracted and sorted by BICOMS 2 software and generated its co-occurrence matrix; the network relationship diagram was drawn by Net Draw software; the cluster analysis was carried out by using g CLUTO software;finally,this research results show that the numbers of domestic and foreign literatures have shown an overall growth trend,but compared with foreign countries,China's research on the real world started late,the overall strength of research was not as good as abroad;and the domestic and foreign research on the real world was uneven in the region,the research in China was mainly distributed in developed provinces and cities,such as Beijing,Guangdong,Shanghai,etc,and there was a lack of close cooperation between provinces and cities; the foreign research are mainly distributed in developed countries such as the United States,the United Kingdom,Germany,et al; the cooperation between countries was relatively close. And the hotspots and core directions of domestic and foreign research were also different. This research was intended to provide reference for the further research of Chinese researchers through the current description of the themes and capability of the real world research in the world.


Assuntos
Bases de Dados Bibliográficas , Pesquisa/tendências , China , Alemanha , Reino Unido , Estados Unidos
8.
Am J Chin Med ; 47(4): 751-767, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31094214

RESUMO

To systematically evaluate the efficacy and safety of berberine for the treatment of hyperlipidemia, six electronic literature databases including SinoMed, CNKI, WanFang Data, PubMed, Embase and The Cochrane Library were searched to collect clinical randomized controlled trials (RCTs) of berberine alone or combined with statins for the treatment of hyperlipidemia from the inception to 8 March 2018. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included RCTs. Then, meta-analysis was performed by using RevMan 5.3 software. A total of 11 RCTs involving 1386 patients were finally included. The results of meta-analysis showed that compared with the placebo group, berberine could significantly reduce the total cholesterol and low-density lipoprotein levels and elevate the high density lipoprotein level ( P<0.05 ). Compared with the simvastatin group, berberine was effective only in reducing the level of triglyceride ( MD=-0.37 , 95% CI: - 0.66, - 0.07, P=0.02 ). There, however, was no statistical significance between the BBR group and simvastatin group in the low density lipoprotein and high density lipoprotein levels. Compared with the simvastatin group, berberine plus simvastatin was more effective in reducing the level of triglyceride ( MD=-0.33 , 95% CI: - 0.46, - 0.20, P<0.00001 ) and total cholesterol ( MD=-0.36 , 95% CI: - 0.60, - 0.12, P=0.003 ). In terms of adverse reactions, the incidence of adverse reactions including transaminase elevation and muscle aches was lower in the berberine alone or combined with simvastatin group than that in the control group, while the instance of constipation was higher. This study suggests that berberine is effective for hyperlipidemia. The quality and quantity of included studies, however, were dissatisfactory, which might decrease the reliability of the results. Higher quality studies are needed to provide more high quality evidence.


Assuntos
Berberina/uso terapêutico , Inibidores de Hidroximetilglutaril-CoA Redutases/uso terapêutico , Hiperlipidemias/tratamento farmacológico , Fitoterapia , Ensaios Clínicos Controlados Aleatórios como Assunto , Sinvastatina/uso terapêutico , Berberina/efeitos adversos , Colesterol/sangue , Bases de Dados Bibliográficas , Quimioterapia Combinada , Humanos , Inibidores de Hidroximetilglutaril-CoA Redutases/efeitos adversos , Hiperlipidemias/sangue , Lipoproteínas HDL/sangue , Lipoproteínas LDL/sangue , Fitoterapia/efeitos adversos , Sinvastatina/efeitos adversos , Resultado do Tratamento , Triglicerídeos/sangue
9.
J Nippon Med Sch ; 86(2): 62-69, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31130567

RESUMO

BACKGROUND: DLEC1 is a tumor-suppressor gene which plays a role in carcinogenesis. The purpose of the current study was to help establish the diagnostic performance of DLEC1 methylation in lung cancer. METHODS: PubMed, Embase, CNKI, and Wanfang databases were searched to obtain eligible studies. The pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to estimate the strength of the associations. The diagnostic value was assessed by the summary receiver operating characteristics test. RESULTS: A total of 7 articles, with 8 studies that included 673 lung cancer and 581 control samples, were collected in this meta-analysis. Our results showed a significant association of DLEC1 hypermethylation with lung cancer (P < 0.00001, OR = 13.93, 95% CI = 9.44-20.55). The frequency of DLEC1 methylation was significantly higher in squamous cell carcinoma (SCC) than adenocarcinoma (AC). Moreover, DLEC1 was more frequently methylated in patients with lung cancer aged 60 years or over, patients with lymphatic metastasis, or patients with stage III/IV lung cancer. In addition, there was a sensitivity value of 0.90 (95% CI = 0.86-0.93) and a specificity value of 0.60 (95% CI = 0.56-0.63), a pooled positive-likelihood ratio (PLR) of 2.27 (95% CI = 2.08-2.48), a pooled negative-likelihood ratio (NLR) of 0.17 (95% CI = 0.12-0.23), a diagnostic odds ratio (DOR) of 14.72 (10.09-21) and an area under the curve (AUC) of 0.8146 using DLEC1 methylation in the prediction of lung cancer risk. CONCLUSION: This meta-analysis confirms that DLEC1 methylation is a promising biomarker for lung cancer.


Assuntos
Adenocarcinoma/diagnóstico , Biomarcadores Tumorais/metabolismo , Carcinoma de Células Escamosas/diagnóstico , Genes Supressores de Tumor , Neoplasias Pulmonares/diagnóstico , Proteínas Supressoras de Tumor/metabolismo , Fatores Etários , Bases de Dados Bibliográficas , Humanos , Neoplasias Pulmonares/patologia , Metástase Linfática , Metilação , Estadiamento de Neoplasias , Razão de Chances , Valor Preditivo dos Testes , Curva ROC , Risco , Sensibilidade e Especificidade
10.
An. psicol ; 35(2): 332-340, mayo 2019. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-181703

RESUMO

Se presentan los resultados del análisis de la difusión y circulación del número de revistas españolas en diferentes bases de datos, nacionales e internacionales. Para ello se realiza un estudio de las revistas que contienen las principales bases de datos bibliográficas hasta el año 2017. El aumento de la presencia de revistas españolas de psicología en las diferentes bases de datos es un indicador que determina el crecimiento y la madurez de esta disciplina y aporta una visión interesante de la actividad científica en psicología y su situación en el contexto internacional. Se muestra que las políticas de estado y las campañas de posicionamiento de universidades, asociaciones y colegios juegan un papel clave en la internacionalización y posicionamiento


We present the results of the analysis of the dissemination and circulation of the number of Spanish journals in different national and international databases. This is a study of the journals that contain the main bibliographic databases until the year 2017. The increase of the presence of Spanish psychology journals in the different databases is an indicator that determines the growth and maturity of this discipline and provides an interesting view of the scientific activity in psychology and its situation in the international context. It shows that state policies and positioning campaigns of universities, associations and schools play a key role in the internationalization and positioning


Assuntos
Humanos , Psicologia/tendências , Publicações Periódicas como Assunto/tendências , Internacionalidade , Disseminação de Informação , Bases de Dados Bibliográficas/tendências , Indicadores Bibliométricos
11.
J Pregnancy ; 2019: 3849596, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30941218

RESUMO

In 1990, Institute of Medicine (IOM) recommended gestational weight gain (GWG) ranges for women in the United States primarily to improve infant birth weight. Changes in key aspects of reproductive health of women of child bearing age, a rising prevalence of obesity, and noncommunicable diseases prompted the revision of IOM guidelines in 2009. However, there is no such recommendation available for Asian women. This systematic review assesses the utility of IOM-2009 guidelines among Indian and other Asian pregnant women in terms of maternal and fetal outcomes. 624 citations were identified using PubMed and Google Scholar, out of which 13 were included. Prospective/retrospective studies of healthy Asian women with a singleton pregnancy which specifically examined fetal-maternal outcomes relative to IOM-2009 guidelines were included. Results. Majority of pregnant Indian women achieved less GWG than the recommendations whereas a mixed trend was noticed among the other Asian pregnant women. The most common fetal-maternal complications among the excessive GWG women were found to be macrosomia, large for gestational age and caesarean section followed by gestational diabetes and hypertension, whereas low birth weight, small for gestational age and preterm birth, was found to be associated with low GWG women. The findings highlight the need for appropriate GWG limits across the different body mass index levels specifically for Indians and other Asian population. However, there are not enough publications regarding the utility of IOM-2009 guidelines among the Indian and other Asian women. Thus, higher-quality researches are warranted in future to further validate the findings of the present review.


Assuntos
Ganho de Peso na Gestação , Guias de Prática Clínica como Assunto , Adolescente , Adulto , Grupo com Ancestrais do Continente Asiático , Índice de Massa Corporal , Cesárea , Bases de Dados Bibliográficas , Diabetes Gestacional/etiologia , Diabetes Gestacional/prevenção & controle , Feminino , Macrossomia Fetal/etiologia , Macrossomia Fetal/prevenção & controle , Idade Gestacional , Humanos , Hipertensão Induzida pela Gravidez/etiologia , Hipertensão Induzida pela Gravidez/prevenção & controle , Recém-Nascido de Baixo Peso , Gravidez , Nascimento Prematuro/etiologia , Nascimento Prematuro/prevenção & controle , Adulto Jovem
12.
Asian J Psychiatr ; 42: 34-41, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30951931

RESUMO

There is an exponential growth in the field of biomedical literature over the years. Although numerous articles are published every year, few of them present important conceptual advances in that particular field and are found to be influential in the evolution of the field. The number of citations a publication receives can be used as a proxy marker of its impact on the field. Hence we aimed to analyze the top cited articles (n = 100) on obsessive compulsive disorder (OCD) as of July 2018. Google scholar database was searched using a freely available software, Publish or Perish. Information related to number of citations, publication title, publication year, name of the journal, country of origin, author details, institution of origin, article type, and article design. The original research articles were further classified into descriptive/epidemiology, mechanism, management, scale/measurement, imaging and medical psychiatry. The citation classics suggest that clinical trials/management, epidemiology and neuroimaging were the most researched areas in the OCD research. These citation classics provide an important insight into the historical developments, like the role of serotonin and caudate in OCD. This approach of citation analysis provides an opportunity to retrieve the classic articles on OCD, and describes the trends in OCD research.


Assuntos
Bibliometria , Transtorno Obsessivo-Compulsivo , Psiquiatria/estatística & dados numéricos , Bases de Dados Bibliográficas , Humanos , Transtorno Obsessivo-Compulsivo/diagnóstico , Transtorno Obsessivo-Compulsivo/epidemiologia , Transtorno Obsessivo-Compulsivo/etiologia , Transtorno Obsessivo-Compulsivo/terapia
13.
Nat Hum Behav ; 3(6): 568-575, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-30988477

RESUMO

The analysis of citations to scientific publications has become a tool that is used in the evaluation of a researcher's work; especially in the face of an ever-increasing production volume1-6. Despite the acknowledged shortcomings of citation analysis and the ongoing debate on the meaning of citations7,8, citations are still primarily viewed as endorsements and as indicators of the influence of the cited reference, regardless of the context of the citation. However, only recently has attention9,10 been given to the connection between contextual information and the success of citing and cited papers, primarily because of the lack of extensive databases that cover both types of metadata. Here we address this issue by studying the usage of citations throughout the full text of 156,558 articles published by the Public Library of Science (PLoS), and by tracing their bibliometric history from among 60 million records obtained from the Web of Science. We find universal patterns of variation in the usage of citations across paper sections11. Notably, we find differences in microlevel citation patterns that were dependent on the ultimate impact of the citing paper itself; publications from high-impact groups tend to cite younger references, as well as more very young and better-cited references. Our study provides a quantitative approach to addressing the long-standing issue that not all citations count the same.


Assuntos
Bibliometria , Publicações Periódicas como Assunto/estatística & dados numéricos , Pesquisa/estatística & dados numéricos , Ciência/estatística & dados numéricos , Bases de Dados Bibliográficas , Humanos
14.
Am J Chin Med ; 47(3): 507-525, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30966774

RESUMO

DL-3-n-butylphthalide (NBP) is widely used as a neuroprotective drug for ischemic stroke in China. There is, however, no established evidence on its efficacy and safety for patients with ischemic stroke. We, therefore, conducted a systematic review and meta-analysis. Major databases were searched to identify randomized controlled trials that assessed the efficacy and safety of NBP on ischemic stroke, reporting outcomes among patients treated with NBP alone or combined with standard anti-ischemic stroke drugs vs. standard anti-ischemic stroke drugs. Continuous data were validated, extracted and synthesized of standardized mean differences (SMDs) by random effects models, while dichotomous data were validated, extracted and synthesized of relative risk (RR) by random effects models. Twelve randomized controlled trials involving 1160 patients were identified. Results suggested that NBP monotherapy is not superior to standard anti-ischemic stroke drugs based on the Barthel Index (SMD, 0.25; 95% CI - 0.14 to 0.63; P=0.21 ) and the National Institutes of Health Stroke Scale (SMD, 0.73; 95% CI - 0.14 to 1.59; P=0.10 ). In contrast, the combination of NBP and standard anti-ischemic stroke drugs appears to be superior to standard drugs alone, again based on both the Barthel index (SMD, 1.65; 95% CI 1.25 to 2.04; P<0.01 ) and National Institutes of Health Stroke Scale (SMD, 1.40; 95% CI 0.72 to 2.09; P<0.01 ). However, the use of NBP may cause adverse event on the function of the liver (RR, 3.55; 95% CI 1.19 to 10.56; P<0.05 ). The combination use of NBP and standard anti-ischemic stroke drugs is more effective than standard drugs. However, more attention should be payed to the adverse effects on liver function. Our findings provided an established evidence of NBP as a neuroprotective drug, which may improve the current guideline for treatment of ischemic stroke.


Assuntos
Benzofuranos/administração & dosagem , Isquemia Encefálica/tratamento farmacológico , Fármacos Neuroprotetores/administração & dosagem , Fitoterapia , Acidente Vascular Cerebral/tratamento farmacológico , Idoso , Benzofuranos/efeitos adversos , Bases de Dados Bibliográficas , Quimioterapia Combinada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fármacos Neuroprotetores/efeitos adversos , Ensaios Clínicos Controlados Aleatórios como Assunto , Resultado do Tratamento
15.
J Card Surg ; 34(6): 377-384, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30953445

RESUMO

OBJECTIVE: To systematically compare clinical outcomes between aortic valve repair and replacement in patients with aortic regurgitation. METHODS: A comprehensive literature search was undertaken among the four major databases (PubMed, Embase, Scopus, and Ovid) to identify all published data comparing clinical outcomes of aortic valve repair vs replacement. Database searched from inception to November 2018. RESULTS: A total of 1071 patients were analyzed in eight articles. Mean age was similar in both groups of patients (47.2 ± 12.8 vs 48.3 ± 12.7 years, P = 0.83, aortic valve repair and replacement, respectively). The preoperative left ventricular ejection fraction was better in the repair group (56.7% ± 4.8 vs 53.3% ± 4.2, P = 0.005). The rate of moderate-to-severe regurgitation and bicuspid aortic valve were similar in both cohorts (81% vs 78%, P = 0.90% and 58% vs 55%, P = 0.46). In-hospital and 1-year mortality was lower in repair cohort, although not reaching statistical significance (1.3% vs 3.6%, P = 0.12; 5.9% vs 9.3%, P = 0.77). Reoperation rate was higher in repair patients at 1 year (8.8% vs 3.7%, P = 0.03). CONCLUSION: Aortic valve repair offers comparable perioperative outcomes to aortic valve replacement in aortic regurgitation patients at the expense of higher late reintervention rate. Larger trials with long-term follow-up are required to confirm the long-term benefits of aortic valve repair.


Assuntos
Insuficiência da Valva Aórtica/cirurgia , Valva Aórtica/cirurgia , Anuloplastia da Valva Cardíaca , Implante de Prótese de Valva Cardíaca , Adulto , Insuficiência da Valva Aórtica/mortalidade , Insuficiência da Valva Aórtica/fisiopatologia , Estudos de Coortes , Bases de Dados Bibliográficas , Feminino , Mortalidade Hospitalar , Humanos , Masculino , Pessoa de Meia-Idade , Reoperação/estatística & dados numéricos , Índice de Gravidade de Doença , Volume Sistólico , Resultado do Tratamento , Função Ventricular Esquerda
16.
Med Ref Serv Q ; 38(1): 87-96, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30942680

RESUMO

The primary goal of this project is to understand how each National Cancer Institute-designated cancer center library, and all libraries that support cancer research, function within their institutions. Through an in-depth survey focused on three major areas (staff, content and tools procurement, and user services), the research team hopes to determine how a cancer-centric library can be successful in supporting quality patient care, research excellence, and education. Additionally, the survey will examine the necessary minimum staffing levels for librarians and information professionals based on organizational size and degree of research focus. The survey will seek out the new skills librarians will need to deliver optimal services. The survey will also explore how content libraries purchase reflects and maps to constituents' current medical and research activities. Libraries within a research intense environment have a responsibility to align with researchers and health care professionals to provide resources and services that support their workflows. Cancer libraries need to be attuned to their institutions' missions, whether that includes excellent patient care, research endeavors, or cutting-edge educational programs. The information gathered from the survey will provide data for this research team to define the vision and standards of excellence for a cancer specialized research library.


Assuntos
Bases de Dados Bibliográficas/normas , Armazenamento e Recuperação da Informação/normas , Bibliotecas Médicas/normas , Desenvolvimento de Coleções em Bibliotecas/normas , Levantamentos de Bibliotecas/normas , Neoplasias , Bases de Dados Bibliográficas/tendências , Previsões , Humanos , Armazenamento e Recuperação da Informação/tendências , Bibliotecas Médicas/tendências , Desenvolvimento de Coleções em Bibliotecas/tendências , National Cancer Institute (U.S.) , Estados Unidos
17.
Med Ref Serv Q ; 38(1): 81-86, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30942682

RESUMO

Providing access to electronic resources is a core service for most libraries, and for more than two decades librarians have used Internet Protocol (IP) addresses as a way to authenticate users and prove they should have access to their institution's licensed materials. But in recent years, IP addresses have become a less accurate method of determining whether a user is affiliated with a particular library. Key players in the publishing industry and academia are working together on a new set of protocols to replace IP authentication called Resource Access for the 21st Century, or RA21. This column will briefly explore what RA21 is, what problems it purports to solve, and what problems it may create. A list of resources for further reading on RA21 is provided.


Assuntos
Acesso à Informação , Bases de Dados Bibliográficas/normas , Internet/normas , Bibliotecas Médicas/normas , Editoração/normas , Humanos , Armazenamento e Recuperação da Informação
18.
Cochrane Database Syst Rev ; 3: MR000041, 2019 03 12.
Artigo em Inglês | MEDLINE | ID: mdl-30860595

RESUMO

BACKGROUND: Systematic reviews are essential for decision-making. Systematic reviews on observational studies help answer research questions on aetiology, risk, prognosis, and frequency of rare outcomes or complications. However, identifying observational studies as part of systematic reviews efficiently is challenging due to poor and inconsistent indexing in literature databases. Search strategies that include a methodological filter focusing on study design of observational studies might be useful for improving the precision of the search performance. OBJECTIVES: To assess the sensitivity and precision of a search strategy with a methodological filter to identify observational studies in MEDLINE and Embase. SEARCH METHODS: We searched MEDLINE (1946 to April 2018), Embase (1974 to April 2018), CINAHL (1937 to April 2018), the Cochrane Library (1992 to April 2018), Google Scholar and Open Grey in April 2018, and scanned reference lists of articles. SELECTION CRITERIA: Studies using a relative recall approach, i.e. comparing sensitivity or precision of a search strategy containing a methodological filter to identify observational studies in MEDLINE and Embase against a reference standard, or studies that compared two or more methodological filters. DATA COLLECTION AND ANALYSIS: Two review authors independently screened articles, extracted relevant information and assessed the quality of the search strategies using the InterTASC Information Specialists' Sub-Group (ISSG) Search Filter Appraisal Checklist. MAIN RESULTS: We identified two eligible studies reporting 18 methodological filters. All methodological filters in these two studies were developed using terms from the reference standard records.The first study evaluated six filters for retrieving observational studies of surgical interventions. The study reported on six filters: one Precision Terms Filter (comprising terms with higher precision while maximum sensitivity was maintained) and one Specificity Terms Filter (comprising terms with higher specificity while maximum sensitivity was maintained), both of which were adapted for MEDLINE, for Embase, and for combined MEDLINE/Embase searches. The study reported one reference standard consisting of 217 articles from one systematic review of which 83.9% of the included studies were case seriesThe second study reported on 12 filters for retrieving comparative non-randomised studies (cNRSs) including cohort, case-control, and cross-sectional studies. This study reported on 12 filters using four different approaches: Fixed method A (comprising of a fixed set of controlled vocabulary (CV) words), Fixed method B (comprising a fixed set of CV words and text words (TW)), Progressive method (CV) (a random choice of study design-related CV terms), and Progressive method (CV or TW) (a random choice of study design-related CV terms, and title and abstracts-based TWs). The study reported four reference standards consisting of 89 cNRSs from four systematic reviews.The six methodological filters developed from the first study reported sensitivity of 99.5% to 100% and precision of 16.7% to 21.1%. The Specificity Terms Filter for combined MEDLINE/Embase was preferred because it had higher precision and equal sensitivity to the Precision Terms Filter. The 12 filters from the second study reported lower sensitivity (48% to 100%) and much lower precision (0.09% to 4.47%). The Progressive method (CV or TW) had the highest sensitivity.There were methodological limitations in both included studies. The first study used one surgical intervention-focused systematic review thus limiting the generalizability of findings. The second study used four systematic reviews but with less than 100 studies. The external validation was performed only on Specificity Terms Filter from the first study Both studies were published 10 years ago and labelling and indexing of observational studies has changed since then. AUTHORS' CONCLUSIONS: We found 18 methodological filters across two eligible studies. Search strategies from the first study had higher sensitivity and precision, underwent external validation and targeted observational studies. Search strategies from the second study had lower sensitivity and precision, focused on cNRSs, and were not validated externally. Given this limited and heterogeneous evidence, and its methodological limitations, further research and better indexation are needed.


Assuntos
Bases de Dados Bibliográficas , Armazenamento e Recuperação da Informação/métodos , Ensaios Clínicos Controlados não Aleatórios como Assunto , Estudos Observacionais como Assunto , /normas , MEDLINE , Sensibilidade e Especificidade , Revisão Sistemática como Assunto
19.
J Card Surg ; 34(4): 170-180, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30843269

RESUMO

BACKGROUND: AngioVac is a new device for filtering intravascular thrombi and emboli. Publications on the device are limited and underpowered to objectively estimate its safety and efficacy. We aimed to overcome this by performing a meta-analysis on the results of AngioVac for treating venous thromboses and endocardial vegetations. METHODS: A systematic literature review was performed to identify all articles reporting cardiac vegetation and/or thrombosis extraction using AngioVac. Endpoints were successful removal, operative mortality, conversion to open surgery, hospital stay, recurrent thromboembolism, and follow-up mortality. Random effect model was used, and pooled event rates (PERs) and incidence rate (IR) were calculated. RESULTS: A total of 42 studies with 182 patients (81 vegetation and 101 thrombosis) were included. Overall mean follow-up times were 3.1 and 0.7 years in vegetation and thrombosis patients, respectively. The PERs for successful removal were 74.5 (confidence interval [CI]: 48.2-90.2), 80.5 (CI: 70.0-88.0), and 32.4 (CI: 17.0-52.8) in vegetation, right atrial/caval venous thrombi, and pulmonary emboli (PE) patients, respectively. The PERs for operative mortalities were 14.6 (CI: 7.7-25.8), 14.8 (CI: 8.5-24.5), and 32.3 (CI: 15.1-56.3), respectively. The PERs for conversion to open surgery were 25.0 (CI: 9.3-51.9) and 12.3 (CI: 5.4-25.6) in vegetation and thrombosis patients, respectively. The IR of recurrent thromboembolism was 0.18 per person per year (PPY) (CI: 0.00-14.69) in vegetation and 0.19 PPY (CI: 0.08-0.48) in thrombosis patients. IR of follow-up mortality was 0.37 PPY (CI: 0.11-1.21) in thrombosis patients. CONCLUSIONS: AngioVac is a viable option for extracting right-sided vegetations and right atrial/caval venous thrombi. Rates of successful extraction and mortality are significantly worse for PE.


Assuntos
Dispositivos de Proteção Embólica , Endocardite Bacteriana/cirurgia , Embolia Pulmonar/cirurgia , Trombectomia/instrumentação , Trombose Venosa/cirurgia , Bases de Dados Bibliográficas , Endocardite Bacteriana/mortalidade , Seguimentos , Humanos , Embolia Pulmonar/mortalidade , Trombectomia/métodos , Resultado do Tratamento , Trombose Venosa/mortalidade
20.
J Endod ; 45(4): 387-393.e2, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30833095

RESUMO

INTRODUCTION: This systematic review and meta-analysis aimed to assess whether machine-assisted agitation resulted in less postoperative pain (PP) compared with syringe irrigation with needle alone in adult patients undergoing root canal treatment. METHODS: A literature search was performed in 3 electronic databases for articles published before August 2018. Randomized clinical trials published in English that compared PP between machine-assisted agitation and syringe irrigation with needles as part of nonsurgical root canal treatment were included. Two authors were independently involved in the article selection process, data extraction, and assessment of the quality of included studies using the revised Cochrane risk of bias tool. The pooled effect estimates of the standardized mean difference (SMD) between machine-assisted agitation and syringe irrigation with needle was calculated by a random effects-modeled meta-analysis. A subgroup meta-analysis was performed. The quality of evidence was evaluated by the Grading of Recommendations, Assessment, Development and Evaluations approach. RESULTS: Six studies were included for systematic review. Meta-analysis was performed using 3 studies and showed that machine-assisted agitation resulted in less PP compared with syringe irrigation with needle at 24 hours (SMD = -0.73; 95% confidence interval, -1.04 to -0.42; I2 = 30.6%) and 48 hours (SMD = -0.60; 95% CI, -0.85 to -0.35; I2 = 0%). The quality of evidence by Grading of Recommendations, Assessment, Development and Evaluations for the PP outcomes (24 hours and 48 hours) was graded as "moderate" quality. CONCLUSIONS: Machine-assisted agitation reduced PP compared with syringe irrigation with needles in nonsurgical root canal treatment. Future clinical trials are needed to support the result of this review.


Assuntos
Dor Pós-Operatória/prevenção & controle , Dor Pós-Operatória/terapia , Ensaios Clínicos Controlados Aleatórios como Assunto , Irrigantes do Canal Radicular/administração & dosagem , Preparo de Canal Radicular/instrumentação , Preparo de Canal Radicular/métodos , Tratamento do Canal Radicular , Irrigação Terapêutica/instrumentação , Irrigação Terapêutica/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Bases de Dados Bibliográficas , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Agulhas , Seringas , Adulto Jovem
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