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1.
J Indian Soc Pedod Prev Dent ; 38(3): 222-231, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33004719

RESUMO

Context: Dental anxiety and fear is not only a psychological problem but also a dental health problem. It is important to understand how the cognitive elements influence child's dental anxiety/fear and interact with their oral health. Objective: This study was conducted among children to determine the association between cognitive vulnerability (CV) with dental fear and their oral health status. Settings and Design: A cross-sectional study was conducted among 500 schoolchildren aged 12-15 years in Bengaluru city. Methodology: The schools and participants were selected by cluster random and systematic random sampling method, respectively. Cognitive vulnerability and Index of Dental Anxiety and Fear (IDAF-4C+) were assessed by a self-administered questionnaire. Oral health status was recorded using the World Health Organization 2013 proforma for children. Statistical Analysis Used: Chi-square test, Student's t-test, Spearman's correlation, and multivariate hierarchical linear regression were used in this study. The statistical significance was considered at P < 0.05. Results: Nearly half of the study participants had cognitive perceptions, dental anxiety/fear, phobia, and stimulus toward dental treatment. Majority had dental caries and gingival bleeding. Cognitive vulnerability, dental anxiety/fear, phobia, and stimulus were independent of the age and gender and were associated with socioeconomic status. A significant correlation was found between participants' CV, IDAF-4C+, dental caries, and gingival bleeding. Cognitive vulnerability was a significant predictor of dental caries and gingival bleeding. Dental anxiety/fear and dental phobia were significant predictors of dental caries. Conclusion: Oral health status was significantly poorer and was associated with CV, dental anxiety/fear, phobia, and stimulus. Cognitive elements together with dental fear influenced oral health.


Assuntos
Ansiedade ao Tratamento Odontológico/epidemiologia , Cárie Dentária/epidemiologia , Adolescente , Criança , Cognição , Estudos Transversais , Medo , Humanos , Índia/epidemiologia , Saúde Bucal
2.
Acta Odontol Latinoam ; 33(2): 90-97, 2020 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-32920610

RESUMO

The aim of this study was to determine the caries situation of three-year-old preschool children residing in low socioeconomic status districts in Lima, Peru. The study is a crosssectional analysis of the caries situation of suburban areas of Lima. A stratified sampling procedure by geographical distribution, considering healthcare centers with a motherand- child health clinic and surrounding preschools as factors, identified 45 randomly selected preschools, of which 17 accepted to participate. Children from 3-year-old classrooms were examined by two independent calibrated dentists using the Caries Assessment Spectrum and Treatment (CAST) instrument at their premises using artificial light, sterile examination mirrors and gauze for drying each tooth before evaluation. ANOVA and the Tamhane method were used to analyze the data. 308 children, mean age 3.4 years (min: 3 years; max: 3 years, 7 months), were examined. The sample prevalence of enamel and dentine carious lesions (CAST code 3-7) was 91.2% while the prevalence of dentine carious lesions (CAST code 4-7) was 58.8%. The mean number of teeth with cavities that had reached the pulp and those that had an abscess or fistula were 2.0% and 0.5% respectively. The majority of enamel and dentine carious lesions were observed in molars. The CAST severity score was 7.0. Mean examination time was 57 seconds. The burden of dental caries of the children at this young age was high.


Assuntos
Cárie Dentária/epidemiologia , Dente Molar/patologia , Pré-Escolar , Estudos Transversais , Cárie Dentária/classificação , Esmalte Dentário/patologia , Feminino , Humanos , Masculino , Peru/epidemiologia , Prevalência , Reprodutibilidade dos Testes , Fatores Socioeconômicos , População Suburbana
3.
Medicine (Baltimore) ; 99(39): e22352, 2020 Sep 25.
Artigo em Inglês | MEDLINE | ID: mdl-32991450

RESUMO

BACKGROUND: Antiretroviral therapy for HIV in sub-Saharan Africa has transformed the highly infectious virus to a stable chronic condition, with the advent of Highly active antiretroviral therapy (HAART). The longterm effects of HAART on the oral health of children are understudied. OBJECTIVE: To compare the effect of lopinavir-ritonavir and lamivudine on oral health indicators (dental caries, gingivitis, tooth eruption, and oral health related quality of life) in 5 to 7 year old HIV-1 exposed uninfected children from the ANRS 12174 trial. METHODS: This study used data collected in 2017 among children aged 5 to 7 years from the Ugandan site of the ANRS 12174 randomized trial (ClinicalTrials.gov no: NCT00640263) implemented between 2009 and 2012 in Mbale district, Eastern Uganda. The intervention was lopinavir-ritonavir or lamuvudine treatment to prevent vertical HIV-1 transmission. One hundred thirty-seven and 139 children were randomized to receive lopinavir-ritonavir or lamivudine treatment at day 7 postpartum to compare efficacy of prevention of vertical HIV-1 transmission. At follow up, the children underwent oral examination using the World Health Organization methods for field conditions. The oral health related quality of life was assessed using the early childhood oral health impact scale. Negative binomial and logistic regression were used for the analysis of data. MAIN OUTCOME MEASURES: Dental caries, gingivitis, tooth eruption, and oral health related quality of life) in 5 to 7 year old HIV-1 exposed uninfected children. RESULTS: The prevalence of dental caries was 48% in the study sample: 49% in the lopinavir-ritonavir arm and 48% in the lamivudine treatment group. The corresponding mean decayed missing filled teeth and standard deviation was 1.7 (2.4) and 2.3 (3.7) The mean number (standard deviation) of erupted permanent teeth was 3.8 (3.7) and 4.6 (3.9) teeth in the lopinavir- and lamivudine group, respectively. The prevalence of reported impacts on oral health was 7% in the lopinavir-ritonavir and 18% in the lamivudine group. Gingivitis had a prevalence of 7% in the lopinavir-ritonavir and 14% lamivudine treatment group. The regression analysis revealed 70% less reported impacts on oral health in lopinavir-ritonavir group than the lamivudine treatment group with an incidence rate ratio of 0.3 (95% confidence interval: 0.1-0.9). CONCLUSIONS: HIV exposed uninfected infants in the lopinavir-ritonavir group reported less impacts on oral health than the lamivudine treatment group. Dental caries, gingivitis, and tooth eruption were not significantly affected by the treatment lopinavir-ritonavir or lamivudine. TRIAL REGISTRATION CLINICALTRIALS. GOV IDENTIFIER: NCT00640263.


Assuntos
Antirretrovirais/uso terapêutico , Terapia Antirretroviral de Alta Atividade/métodos , Infecções por HIV/tratamento farmacológico , Saúde Bucal/estatística & dados numéricos , Fármacos Anti-HIV/farmacologia , Fármacos Anti-HIV/uso terapêutico , Estudos de Casos e Controles , Criança , Pré-Escolar , Cárie Dentária/tratamento farmacológico , Cárie Dentária/epidemiologia , Quimioterapia Combinada , Feminino , Gengivite/tratamento farmacológico , Infecções por HIV/prevenção & controle , Infecções por HIV/transmissão , HIV-1/efeitos dos fármacos , Humanos , Transmissão Vertical de Doença Infecciosa/prevenção & controle , Lamivudina/farmacologia , Lamivudina/uso terapêutico , Lopinavir/farmacologia , Lopinavir/uso terapêutico , Masculino , Avaliação de Resultados em Cuidados de Saúde , Prevalência , Qualidade de Vida , Ritonavir/farmacologia , Ritonavir/uso terapêutico , Erupção Dentária/efeitos dos fármacos , Uganda/epidemiologia
4.
Medicine (Baltimore) ; 99(35): e21767, 2020 Aug 28.
Artigo em Inglês | MEDLINE | ID: mdl-32871897

RESUMO

Risk factors such as smoking and sugar intake threaten the health of human being at an individual national level as well as at a global level. The globalization affect health indirectly through macro and micro-level factors. This study aimed to identify the global trend of dental caries according to countries national income level, and to examine the role of globalization, health services, obesity, and sugar consumption on dental caries. Data for 160 countries were collected for the time period of the 1990s to 2010s. The final sample included 46 countries with complete data (21 high income countries (HIC) and 25 middle and low income countries (MLIC)). The main dependent variable was the mean decayed, missing, and filled teeth (DMFT) index of 12-year-olds as an indicator of dental caries. Globalization was a main independent variable which was measured by economic growth, urbanization and economic freedom. Other independent variables were health services, obesity and sugar consumption. The data were analyzed first using repeated measures analysis of variance to compare dental caries trends in HIC and MLIC. Then, using multiple linear regression and partial least squares structural equation modeling (PLS-SEM), the relationships between globalization, health services, obesity, sugar consumption, and dental caries were examined. The results of PLS-SEM revealed that globalization was associated with lower DMFT in HIC. The global dental caries trend had a declined pattern, but this pattern has been attenuated in MLIC after the new millennium. There is a need for policy change and regulations on sugar trade especially in MLIC to diminish the adverse consequences of globalization, and to improve population dental health.


Assuntos
Índice CPO , Cárie Dentária/epidemiologia , Países Desenvolvidos/estatística & dados numéricos , Países em Desenvolvimento/estatística & dados numéricos , Internacionalidade , Criança , Açúcares da Dieta , Desenvolvimento Econômico , Acesso aos Serviços de Saúde/estatística & dados numéricos , Humanos , Análise de Classes Latentes , Modelos Lineares , Obesidade/epidemiologia , Urbanização
5.
J Am Dent Assoc ; 151(10): 782-789, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32979957

RESUMO

BACKGROUND: The authors' aim was to examine the association between sugar-sweetened beverage (SSB) consumption and the prevalence and severity of the caries experience in children and adults in the United States. METHODS: The authors analyzed data obtained from 14,192 people aged 2 through 74 years, who participated in the National Health and Nutrition Examination Survey from 2011 through 2014. Using descriptive analyses, the authors assessed the distributions of sociodemographic characteristics overall and via SSB intake. The authors used multivariable logistic regression to estimate the association of untreated and severe untreated caries with SSB consumption in all age groups. RESULTS: Across all ages, male participants were more likely than female participants to consume SSBs, and consumption was higher in non-Hispanic black and Hispanic populations. Relative to those who did not consume SSBs, people aged 20 through 44 years who consumed SSBs had significantly higher odds of having untreated caries (adjusted odds ratio [AOR], 1.27; 95% confidence interval [CI], 1.04 to 1.55) and severe untreated caries (AOR, 1.36; 95% CI, 1.15 to 1.60). Adolescents aged 9 through 19 years had significantly higher odds of having untreated caries (AOR, 1.37; 95% CI, 1.05 to 1.80), and middle-aged adults (45-64 years) had significantly higher odds of severe untreated caries (AOR, 1.46; 95% CI, 1.10 to 1.92) relative to those who did not consume SSBs. CONCLUSIONS: Consumption of SSBs was associated with increased caries experience among young children and increased risk of developing untreated caries in all age groups of children and adults. Continued efforts by policy makers, public health leaders, and clinicians to reduce consumption of SSBs across the life span are paramount.


Assuntos
Cárie Dentária , Inquéritos Nutricionais , Adolescente , Adulto , Afro-Americanos , Idoso , Bebidas/efeitos adversos , Bebidas/análise , Criança , Pré-Escolar , Estudos Transversais , Cárie Dentária/epidemiologia , Cárie Dentária/etiologia , Sacarose na Dieta/efeitos adversos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Bebidas Adoçadas com Açúcar , Estados Unidos/epidemiologia , Adulto Jovem
6.
J Med Life ; 13(2): 249-254, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32742522

RESUMO

Early childhood caries is a condition that impacts oral health-related quality of life of children's development and well being and also affects parents' work hours and poses a financial burden on them. Our objective was to study and compare the impact of early childhood caries on the quality of life of preschool children aged 22-70 months and their caregivers in an urban and rural population using the early childhood oral health impact scale. The study was conducted on children of the Rangareddy district, Telangana state, aged between 22 -70 months affected by early childhood caries and their parents/guardians. The subjects were given a questionnaire to measure the early childhood oral health impact scale, and the filled questionnaires were analyzed and tabulated. The mean early childhood oral health impact scale and domain scores for the rural population were significantly higher than that of the urban population signifying a more mediocre quality of life. There was a weak positive and insignificant relationship between early childhood caries and the early childhood oral health impact scale in the rural population, whereas there was a moderately strong, significant positive relationship between the two in the urban population. Oral health-related quality of life of young children enables parents and caregivers to implement positive dental care practices.


Assuntos
Cuidadores , Cárie Dentária/epidemiologia , Saúde Bucal , Qualidade de Vida , População Rural , População Urbana , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Pais , Inquéritos e Questionários
7.
Periodontol 2000 ; 84(1): 69-83, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32844424

RESUMO

As a result of aging populations, in the future, dental practitioners will be caring for more older adults than ever before. These older adults, especially in developed countries, will demand a greater number of dental services, driven by increased tooth retention and an expectation of excellent oral healthcare throughout the life course. Further, the global rise in the prevalence and incidence of chronic diseases will increase the risk and/or severity of oral diseases and add a layer of complexity to the management of oral diseases in older adults. More older adults will be at a higher risk of periodontal disease and root caries as a result of reduced tooth loss and edentulism. This article reviews information on periodontitis and root caries, oral diseases which reflect the cumulative risk of the individual, and which are best addressed through prevention. Oral healthcare providers must embrace the concept of lifelong emphasis on prevention, as well as participation as active members of a healthcare team which provides healthcare for older adults in various settings (eg, hospital/clinic-based care, community-based settings, and long-term care facilities). National guidelines that address oral health are being considered by some countries, and if these are implemented they will increase the accessibility to oral health for older adults. In parallel to this, revisions of existing older adult insurance schemes (eg, the inclusion of routine oral healthcare in the US Medicare program) would promote the maintenance of a functional dentition that is pain-free and conducive to general health. The opportunity exists to implement a holistic approach to oral health that will align oral health with general health and emphasize that true health can only be achieved with the inclusion of oral health.


Assuntos
Cárie Dentária/epidemiologia , Cárie Dentária/prevenção & controle , Cárie Dentária/terapia , Doenças Periodontais/epidemiologia , Doenças Periodontais/prevenção & controle , Doenças Periodontais/terapia , Idoso , Odontólogos , Humanos , Medicare , Saúde Bucal , Papel Profissional , Estados Unidos
8.
PLoS One ; 15(8): e0237581, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32797062

RESUMO

OBJECTIVES: To investigate the role of gastroesophageal reflux disease (GERD) and laryngopharyngeal reflux (LPR) in the development of dental disorders. METHODS: The first outcome was review of the role of reflux in the development of dental disorders in adults. The second outcome was review of the potential pathophysiological mechanisms underlying the association between reflux and dental disorders. Three investigators screened publications for eligibility and exclusion based on predetermined criteria through a literature search conducted on PubMed, Cochrane Library, and Scopus according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). RESULTS: From 386 publications, 24 studies were kept for analysis. Objective approaches were used in 16 studies to confirm GERD diagnosis. Pharyngeal reflux episodes (LPR) were considered in 2 studies. No study considered nonacid reflux. The study results supported a higher prevalence of dental erosion and caries in reflux patients compared with healthy individuals. Patients with dental erosion have a higher prevalence of reflux than controls. The pathophysiological mechanisms would involve changes in the saliva physiology. No study investigated the microbiota modifications related to reflux although the findings are supporting the critical role of microbiota change in the development of dental disorders. There is an important heterogeneity between studies about diagnostic methods and clinical outcome evaluation. CONCLUSION: The involvement of reflux in the development of dental disorders is not formally demonstrated and requires future investigations considering pharyngeal acid and nonacid reflux episodes and in particular their potential impact on oral microbiota.


Assuntos
Cárie Dentária/epidemiologia , Esofagite Péptica/epidemiologia , Refluxo Laringofaríngeo/epidemiologia , Humanos , Prevalência , Fatores de Risco , Saliva/química
9.
Acta Odontol Latinoam ; 33(1): 38-44, 2020 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-32621598

RESUMO

The aim of this study is to assess the prevalence of odontogenic infection in low-income Brazilian schoolchildren and evaluate its association with the subjective variables of oral health-related quality of life and dental pain. In this cross-sectional study, 230 schoolchildren aged eight to ten years old underwent a clinical oral survey in which the DMFT/dmft and PUFA/pufa indexes were measured. Afterward, children responded individually to the Child Perceptions Questionnaire (CPQ8-10) and self-reports of dental pain were collected. Data were statistically analyzed using MannWhitney or Kruskal-Wallis test with a post-test by Dunn's and Pearson correlation. Of the children evaluated, 42.6% had odontogenic infection and 80% reported experiencing dental pain. Children's age (p = 0.034) and past experience of dental pain (p < 0.002) were associated with odontogenic sepsis, in addition to impairment of their emotional well-being (p = 0.008), social welfare (p = 0.009) and overall impact on quality of life (p = 0.019). Toothache intensity (p < 0.001), frequency (p < 0.001) and duration (p < 0.001) were correlated to the overall impact on children's quality of life. The prevalence of odontogenic infection remains high among low-income Brazilian schoolchildren. Pediatric infection and its related pain induce not only various biological disorders but also impair children's self-perception of quality of life.


Assuntos
Cárie Dentária/psicologia , Infecções/epidemiologia , Qualidade de Vida , Odontalgia/epidemiologia , Brasil/epidemiologia , Criança , Estudos Transversais , Assistência Odontológica para Crianças/estatística & dados numéricos , Cárie Dentária/epidemiologia , Humanos , Infecções/etiologia , Saúde Bucal , Pobreza/estatística & dados numéricos , Prevalência , Fatores Socioeconômicos , Estudantes/psicologia , Estudantes/estatística & dados numéricos , Inquéritos e Questionários , Odontalgia/psicologia
10.
Medicine (Baltimore) ; 99(28): e20988, 2020 Jul 10.
Artigo em Inglês | MEDLINE | ID: mdl-32664102

RESUMO

An effective prevention policy for dental caries is absent in Jilin, China because of outdated and insufficient data. Therefore, this study aimed to investigate dental caries status and related risk indicators among 12-year-old students in Jilin Province.We conducted a cross-sectional investigation among 2324 children aged 12 years from 9 regions of Jilin in 2017. Caries was evaluated with the decayed-missing-filled teeth index and the significant caries index. The rate of pit and fissure closure, education level of patients, brushing habits, and sugar consumption were evaluated in a structured questionnaire. The associated risk indicators of caries were also assessed through logistic regression analysis.The prevalence of dental caries is 56.11%, and the value of decayed-missing-filled teeth was 1.53. More dental caries was found in students living in high-fluorine areas (P < .01). The results of logistic regression analysis show that females, poor self-assessment of oral health, toothache experience, dental visits, and education levels of parents are risk indicators for caries (P < .01).Regarding the current status of DC among 12-year-old students in Jilin Province, (1) The high-fluorine areas have lower DC prevalence than the non-high fluorine areas, (2) Female students have higher DC prevalence than male students, (3) Poor self-assessment of dental health, toothache experience, dental visits, and low education levels of parents can increase the risk of dental caries.


Assuntos
Cárie Dentária/epidemiologia , Criança , China/epidemiologia , Estudos Transversais , Índice CPO , Feminino , Humanos , Masculino , Fatores de Risco , Estudantes
11.
PLoS One ; 15(7): e0232998, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32609719

RESUMO

OBJECTIVES: The study tried to determine if malnutrition (underweight, stunting, wasting, overweight) and enamel defects (enamel hypoplasia, hypomineralized second molar, amelogenesis imperfecta, fluorosis) were associated with early childhood caries (ECC). The study also examined whether malnutrition was associated with the presence of enamel defects in 0-5-year-old children. METHODS: The study was a secondary analysis of primary data of a cross-sectional study assessing the association between maternal psychosocial health and ECC in sub-urban Nigerian population collected in December 2018 and January 2019. One hundred and fifty nine children were recruited. Exploratory variables were malnutrition and enamel defects. The outcome variables were the prevalence of ECC in 0-2-year-old, 3-5-year-old, and 0-5-year-old children. Multivariable Poisson regression analysis was used to determine the associations, and socioeconomic status, oral hygiene status, and frequency of in-between-meals sugar consumption were adjusted for. The adjusted prevalence ratios, 95% confidence intervals, and p values were calculated. RESULTS: The prevalence of ECC was 2.1% in 0-2-year-old children and 4.9% in 3-5-year-old children. In adjusted models, underweight, stunting, and wasting/overweight were not significant risk indicators for ECC in either age group. 0-2-year-old children who had amelogenesis imperfecta (p<0.001) and fluorosis (p<0.001) were more likely to have ECC than were children who did not have these lesions. 3-5-year-old children who had hypoplasia (p = 0.004), amelogenesis imperfecta (p<0.001) and fluorosis (p<0.001) were more likely to have ECC than were children who did not have these lesions. 0-5-year-old children with hypoplasia (p<0.001) and fluorosis (p<0.001) were more likely to have ECC than were children who did not have these lesions. There were significant associations between various types of malnutrition and various types of enamel defects. CONCLUSION: Although different types of malnutrition were associated with enamel defects, and enamel defects were associated with ECC, malnutrition was not associated with ECC. Further studies are needed to clarify the association between malnutrition and genetically and toxin-induced enamel defects.


Assuntos
Cárie Dentária/epidemiologia , Esmalte Dentário/patologia , Desnutrição/epidemiologia , Criança , Pré-Escolar , Cárie Dentária/complicações , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Desnutrição/complicações , Nigéria , Prevalência , Fatores de Risco , População Urbana/estatística & dados numéricos
12.
PLoS One ; 15(6): e0234122, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32559191

RESUMO

This study aimed to assess changes in epidemiological estimates and treatment needed when initial caries lesions are included in a population-based survey of preschool children. A cross-sectional survey was conducted in a Brazilian municipality, collecting data of preschool children in 16 health centers. Caries detection used the merged codes (epi-codes) for ICDAS/ICCMS. An option for treatment, according to ICCMS, was chosen during the examination. Caries experience (dmft/dmfs) and prevalence were estimated considering three thresholds (A- initial, moderate, and severe lesions, B- only moderate and severe lesions and C- severe lesions). Incremental need for non-operative care was also verified. The sample consisted of 663 children aged 2-4 years (response rate of 99.85%). Including initial lesions, a 2-fold increase in dmft was observed (A: 3.36, B: 1.02, p<0.001). With the inclusion, the caries prevalence increased to 75% compared to threshold B only (28%). The majority (76%) of children who required any intervention (56%) should be scheduled for non-operative care. We suggest that including initial caries lesions in an epidemiological survey may significantly impact assessment of population caries experience.


Assuntos
Cárie Dentária/patologia , Brasil/epidemiologia , Pré-Escolar , Estudos Transversais , Cárie Dentária/epidemiologia , Feminino , Humanos , Masculino , Prevalência , Índice de Gravidade de Doença
13.
Braz Oral Res ; 34: e055, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32578798

RESUMO

This study was performed to evaluate the interplay between dental caries, nutritional status, and genetic polymorphisms in TAS1R1 and TAS1R2 (taste receptor, type 1, member 1 and 2) in preschool children and pre-adolescents. We included 525 subjects (306 preschool children and 219 pre-adolescents). Parents/caregivers answered a self-administered questionnaire about their children's systemic health, characteristics, oral hygiene habits, and diet. Clinical examination was performed to evaluate dental caries and nutritional status. Saliva samples were collected for DNA extraction. The genotyping of rs17492553 ( TAS1R1 ), rs3935570, and rs4920566 ( TAS1R2 ) polymorphisms was performed using real-time PCR with Taqman Genotyping Master Mix and SNP assay. Both univariate and multivariate Poisson regression analyses with robust variance were used for the data analysis. In preschool children, consumption of sweets between meals increased the prevalence of dental caries by 85% (PR c = 1.85; 95%CI 1.39-2.46; p < 0.001), whereas in pre-adolescents, this prevalence increased by 34% (PR a = 1.34; 95%CI 1.11-1.62; p = 0.002), regardless of genetic polymorphisms . Moreover, individuals carrying at least one allele C in rs17492553 presented 23% more prevalence of dental caries (PR a = 1.23; 95%CI 1.02-1.49 p = 0.030). Nutritional status was not associated with dental caries, neither with genetic polymorphisms . Consumption of sweets between meals increased the prevalence of dental caries. In pre-adolescents, rs17492553 genetic polymorphism in TAS1R1 was associated with dental caries.


Assuntos
Cárie Dentária/genética , Estado Nutricional/genética , Polimorfismo Genético , Receptores Acoplados a Proteínas-G/genética , Adolescente , Brasil/epidemiologia , Criança , Índice CPO , Cárie Dentária/epidemiologia , Feminino , Humanos , Masculino , Prevalência , Reação em Cadeia da Polimerase em Tempo Real , Análise de Regressão , Fatores de Risco , Inquéritos e Questionários , Paladar/genética
14.
Artigo em Inglês | MEDLINE | ID: mdl-32545837

RESUMO

BACKGROUND: This study aimed at assessing socioeconomic inequalities in the increment of dental caries and growth among preschool Chinese children, and to assess the best predictor of socioeconomic inequality for each of these conditions. METHODS: This is a longitudinal population-based study. The sample data included preschool children living in three cities of the Liaoning Province, China. At baseline, 15 kindergartens with 1111 participants were included and dropped to 772 with a response rate of 70% at follow-up. Mean ages at baseline and follow-up were 50.82 and 60.55 months, respectively. Median follow-up time was 10.12 months. Data were collected through structured questionnaire, oral examination and anthropometric measurement. The questionnaire collected information on sex, age, family income, mother's education and children's dietary habits. The numbers of decayed, missing and filled teeth (DMFT) was used to indicate dental caries. Weight- and height-for-age z-scores were calculated using the WHO Growth Standard. Multilevel analysis was used to assess the association between baseline socioeconomic position and each of dental caries and child's growth. RESULTS: Mother's education was negatively associated with increments of DMFT. Family income was not significantly associated with DMFT in the fully adjusted model. The association persisted after accounting for other socioeconomic and dietary factors. Higher income was positively related to an increase in the weight-for-age z-score. The relationship between income and changes in the height-for-age z-score was positive and significant in the second highest income group. CONCLUSIONS: Mother's education appeared to be the strongest predictor of increments of dental caries. Only income was significantly associated with an increase in children's weight and height.


Assuntos
Cárie Dentária , Disparidades nos Níveis de Saúde , Fatores Socioeconômicos , Pré-Escolar , China/epidemiologia , Estudos Transversais , Índice CPO , Cárie Dentária/epidemiologia , Feminino , Humanos , Renda , Masculino , Mães
15.
Aust Dent J ; 65 Suppl 1: S40-S46, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-32583586

RESUMO

BACKGROUND: The prevalence of root caries in Australia is expected to increase due to an ageing population and increase in tooth retention. This report presents findings from the Australian National Study of Adult Oral Health 2017-18. METHODS: A stratified random sample of 15 731 Australians aged ≥15 years participated in a telephone or online survey. Of those, 5022 dentate people underwent an oral assessment. Carious root surfaces were defined as ≥1 mm of affected dentine/cementum. Prevalence was defined as the percentage with ≥one natural tooth with untreated caries on root surfaces. Severity was measured as the mean number of root surfaces with caries. RESULTS: Prevalence of untreated root caries in the Australian adult dentate population was 8.2% and increased with increasing age (range 2%-17.8%). Men (9.3%) compared to women (7.2%), people living in remote (18.0%) versus regional (9.3%) and major cities (7.6%), and those with the lowest household income (15.4%) compared to middle (7.6%) and highest tertile (3.2%) had untreated root caries. The average number of decayed or filled root surfaces in the Australian adult population was 1.1 (95% CI 0.9, 1.2). CONCLUSIONS: Root caries was associated with older age, living outside a major city and lower income.


Assuntos
Cárie Dentária/epidemiologia , Cárie Radicular , Adulto , Idoso , Austrália/epidemiologia , Índice CPO , Feminino , Humanos , Masculino , Saúde Bucal , Prevalência
16.
Aust Dent J ; 65 Suppl 1: S32-S39, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-32583588

RESUMO

AIMS: To report the experience of coronal dental caries in the Australian adult population. METHODS: Dentate people aged 15 years and over were online or telephone interviewed, and dental examined (n = 5022). The number of decay, missing and filled surfaces (DMFS) were recorded. Independent variables were demographic, socioeconomic conditions and dental care characteristics. Proportions of DMFS >0, average DMFS and its components were calculated. RESULTS: Overall, 32.1% had decayed surfaces, with a higher proportion found in males (34.7%) and 40% higher in those living in remote areas than in those living in major city and regional areas. The prevalence of decayed surfaces varied from 37.4% (lowest income group) to 25.0% (highest income group). The mean number of decayed surfaces was three times higher in the lowest income group compared to the highest one. Uninsured people had a higher prevalence of decayed surfaces and lower mean of filling surfaces than insured group. Participants with an unfavourable pattern of dental visiting had two times higher prevalence of decay than their counterparts. Overall, three quarters (77.4%) had at least one filling in their permanent dentition. This percentage increased from 61.6% among 15-34 year olds, to 88.0% among those aged 55-74 years. CONCLUSION: Socioeconomic inequalities in caries experience persist in Australia.


Assuntos
Cárie Dentária/epidemiologia , Adolescente , Adulto , Idoso , Austrália/epidemiologia , Índice CPO , Humanos , Renda , Masculino , Pessoa de Meia-Idade , Prevalência , Fatores Socioeconômicos
17.
Artigo em Inglês | MEDLINE | ID: mdl-32545394

RESUMO

To our knowledge, recent oral health data in Romania is poor, as no comprehensive oral health surveys have been carried out in the last five years. The present cross-sectional oral health survey aimed to assess the dental health status in 6 and 12-year old children from Transylvania, in correlation with their family background, oral-health behavior, and the intake of sweets. The study was conducted on 290 children from nine schools in the Transylvanian region of Romania. The study consisted of the clinical examination of children, recording of data in an International Cavity Detection and Assessment System (ICDAS) chart, and a questionnaire referring to the child's parental education, frequency, and motivation of visits to the dentist, dental care habits, and the intake of sweets. Our results indicated that the most prevalent ICDAS scores recorded in 6-year-old children were "0A" (p = 0.001464), "03" (p = 0.00366), "05" (p = 0.005563), "06" for rural areas. Restorations were statistically more prevalent in the urban population (p = 0.000076). The ICDAS score for 12-year old children was "03" (p = 0.003614) and prevalent in the urban area. The ICDAS score for the rural area was "04" (p = 0.0056). Comparing dental health status with family background demonstrated a strong correlation for the group of 6-year-old children, and a lack of correlation for the 12-year-old children. The number of dental visits corelated with the parents' backgrounds, and was higher in the urban population. Frequent hygiene habits (toothbrushing) were statistically correlated with lower ICDAS scores: "04" (p = 0.016482), "05" (p = 0.039127), "06" (p = 0.010785). Eating habits in both age groups were associated with statistically significant differences of "03", "04", "05", "06", "0A" in the ICDAS score. The obtained results provided clarification on the dental health situation in Romania and the potential risk factors of caries among the population, and therefore it could be used as a starter point for future studies to investigate, in depth, the effects of various variables on cavities found in Transylvanian schoolchildren.


Assuntos
Cárie Dentária , Higiene Bucal , Criança , Estudos Transversais , Índice CPO , Cárie Dentária/epidemiologia , Feminino , Comportamentos Relacionados com a Saúde , Humanos , Masculino , Saúde Bucal , Prevalência , Romênia/epidemiologia , Inquéritos e Questionários
18.
BMC Med Genet ; 21(1): 97, 2020 05 07.
Artigo em Inglês | MEDLINE | ID: mdl-32380970

RESUMO

BACKGROUND: Amelogenesis imperfecta (AI) is a highly heterogeneous group of hereditary developmental abnormalities which mainly affects the dental enamel during tooth development in terms of its thickness, structure, and composition. It appears both in syndromic as well as non-syndromic forms. In the affected individuals, the enamel is usually thin, soft, rough, brittle, pitted, chipped, and abraded, having reduced functional ability and aesthetics. It leads to severe complications in the patient, like early tooth loss, severe discomfort, pain, dental caries, chewing difficulties, and discoloration of teeth from yellow to yellowish-brown or creamy type. The study aimed to identify the disease-causing variant in a consanguineous family. METHODS: We recruited a consanguineous Pashtun family of Pakistani origin. Exome sequencing analysis was followed by Sanger sequencing to identify the pathogenic variant in this family. RESULTS: Clinical analysis revealed hypomaturation AI having generalized yellow-brown or creamy type of discoloration in affected members. We identified a novel nonsense sequence variant c.1192C > T (p.Gln398*) in exon-12 of SLC24A4 by using exome sequencing. Later, its co-segregation within the family was confirmed by Sanger sequencing. The human gene mutation database (HGMD, 2019) has a record of five pathogenic variants in SLC24A4, causing AI phenotype. CONCLUSION: This nonsense sequence variant c.1192C > T (p.Gln398*) is the sixth disease-causing variant in SLC24A4, which extends its mutation spectrum and confirms the role of this gene in the morphogenesis of human tooth enamel. The identified variant highlights the critical role of SLC24A4 in causing a rare AI type in humans.


Assuntos
Amelogênese Imperfeita/genética , Antiporters/genética , Cárie Dentária/genética , Predisposição Genética para Doença , Adulto , Amelogênese Imperfeita/epidemiologia , Amelogênese Imperfeita/patologia , Códon sem Sentido/genética , Cárie Dentária/epidemiologia , Cárie Dentária/patologia , Esmalte Dentário/metabolismo , Éxons/genética , Feminino , Humanos , Masculino , Morfogênese/genética , Paquistão/epidemiologia , Linhagem , Perda de Dente/genética , Perda de Dente/fisiopatologia , Sequenciamento Completo do Exoma , Adulto Jovem
19.
Artigo em Inglês | MEDLINE | ID: mdl-32408678

RESUMO

The present survey provides a quantitative assessment of caries prevalence, covering a group of 3-5 year-old children from an urban area generally with a high income in the province of Milan, and a comparison of the obtained results with the data presented by the W.H.O. A cross-sectional study was conducted in the period from March to September 2018 to investigate the prevalence of caries in a sample of 160 children (82 females and 78 males). The absence/presence of caries was defined as a dependent variable. Factors concerning lifestyle, diet, oral habits, oral hygiene, the presence and type of malocclusion and mouth breathing attitude were considered as risk factors. Data were analyzed by Chi-square (χ2) and regression tests using SPSS (version 25.0) software. In total, 84.38% of children (135 out of 160) showed no caries. A regression analysis demonstrated that children who had already received an early first dental visit were mostly those already affected by caries. Furthermore, children who had four meals daily or more were less exposed to the risk of developing caries compared to those who had only 1-3 meals daily. The caries prevalence of preschool children from urban areas with a high income in Milan province is relatively close to that considered acceptable by the W.H.O. in its proposed goals for the year 2020. Therefore, it can be concluded from the obtained results that there is a possibility for further improvement in preventing caries growth at its initial stage: it is necessary for the number of meals daily consumed by children to be controlled by parents, and conducting a dental visit early in childhood must not be neglected.


Assuntos
Cárie Dentária , População Urbana , Pré-Escolar , Estudos Transversais , Índice CPO , Cárie Dentária/epidemiologia , Feminino , Humanos , Itália/epidemiologia , Masculino , Prevalência , Fatores de Risco
20.
Medicine (Baltimore) ; 99(18): e19595, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32358344

RESUMO

To evaluate the effect of chronic malnutrition on the oral health of children aged 1 to 5 years.An observational, analytical, cross-sectional study was conducted and involved 82 children (12-71 months of age). Nutritional status was evaluated using anthropometric indicators and oral health status/caries prevalence was measured. Non-stimulated saliva was collected and flow rate and buffering capacity was measured.The mean dmft index was 1.38 for the adequately nourished children, 3.04 for those with mild malnutrition, 2.5 for those with moderate malnutrition and 2.4 for those with severe malnutrition. 69 of the 82 children had low to very low buffering capacity. No significant differences among the groups were found between malnutrition and age, buffering capacity or the dmft index (P > .05). However, significant differences in salivary flow were found among the different malnutrition categories (P < .05). Spearman correlation coefficient revealed a weak negative correlation between nutrition and salivary flow (r = -0.267).Malnutrition exerts a negative impact on the oral cavity of children and a reduction in salivary flow rate was observed with the increase in malnutrition. Diagnosing the effects of malnutrition in oral environment of children is important because it could improve the quality of life and give them an adequate treatment.


Assuntos
Transtornos da Nutrição Infantil/fisiopatologia , Cárie Dentária/epidemiologia , Saúde Bucal , Transtornos da Nutrição Infantil/complicações , Pré-Escolar , Doença Crônica , Estudos Transversais , Cárie Dentária/etiologia , Feminino , Humanos , Lactente , Masculino , Estado Nutricional , Prevalência , Saliva/metabolismo
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