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An Bras Dermatol ; 94(1): 96-98, 2019 Jan-Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30726473


Histoplasmosis usually presents primarily as lung infection. Occasionally, mainly in immunocompromised hosts, it can spread and cause systemic manifestations. Skin lesions have been reported in 10 to 15 percent of cases of disseminated histoplasmosis, and panniculitis has been described as an unusual form of presentation in affected patients. We present the case of a patient with systemic lupus erythematosus who presented cellulitis due to disseminated histoplasmosis.

Histoplasmose/patologia , Lúpus Eritematoso Sistêmico/complicações , Paniculite/patologia , Biópsia , Celulite/imunologia , Celulite/microbiologia , Celulite/patologia , Feminino , Histoplasma/isolamento & purificação , Histoplasmose/imunologia , Humanos , Imunocompetência , Pessoa de Meia-Idade , Paniculite/imunologia , Paniculite/microbiologia
Plast Reconstr Surg ; 143(4): 1077-1086, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30730492


BACKGROUND: This study was performed to investigate gender differences in gluteal subcutaneous architecture and biomechanics to better understand the pathophysiology underlying the mattress-like appearance of cellulite. METHODS: Ten male and 10 female body donors [mean age, 76 ± 16.47 years (range, 36 to 92 years); mean body mass index, 25.27 ± 6.24 kg/m (range, 16.69 to 40.76 kg/m)] were used to generate full-thickness longitudinal and transverse gluteal slices. In the superficial and deep fatty layers, fat lobule number, height, and width were investigated. The force needed to cause septal breakage between the dermis and superficial fascia was measured using biomechanical testing. RESULTS: Increased age was significantly related to decreased dermal thickness, independent of sex (OR, 0.997, 95 percent CI, 0.996 to 0.998; p < 0.0001). The mean number of subdermal fat lobules was significantly higher in male body donors (10.05 ± 2.3) than in female body donors (7.51 ± 2.7; p = 0.003), indicating more septal connections between the superficial fascia and dermis in men. Female sex and increased body mass index were associated with increased height of superficial fat lobules. The force needed to cause septal breakage in male body donors (38.46 ± 26.3 N) was significantly greater than in female body donors (23.26 ± 10.2 N; p = 0.021). CONCLUSIONS: The interplay of dermal support, septal morphology, and underlying fat architecture contributes to the biomechanical properties of the subdermal junction. This is influenced by sex, age, and body mass index. Cellulite can be understood as an imbalance between containment and extrusion forces at the subdermal junction; aged women with high body mass index have the greatest risk of developing (or worsening of) cellulite.

Tecido Adiposo/fisiopatologia , Nádegas/anatomia & histologia , Celulite/fisiopatologia , Tela Subcutânea , Tecido Adiposo/diagnóstico por imagem , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Envelhecimento/fisiologia , Fenômenos Biomecânicos , Índice de Massa Corporal , Nádegas/diagnóstico por imagem , Celulite/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Caracteres Sexuais , Tela Subcutânea/anatomia & histologia , Tela Subcutânea/diagnóstico por imagem , Tela Subcutânea/fisiologia
Med Hypotheses ; 116: 132-135, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29857897


Cellulite constitutes a major aesthetic concern affecting the majority of post-adolescent women. Current epidemiological evidence supports that the prevalence of cellulite is significantly higher in industrialized societies indicating that environmental factors have crucial role in its pathogenesis and perpetuation. Endocrine disrupting chemicals, which exist ubiquitously in the environment, are able to alter hormonal and homeostatic systems. Several of them exert agonist effects by binding to estrogen receptors and mimicking the biological activity of estrogens. Since elevated estrogen concentration is prerequisite for cellulite, the present article suggests that endocrine disrupting chemicals may be key determinants in the initiation and deterioration of cellulite either by stimulating estrogen receptors or increasing their circulating levels due to interference with enzymes and binding proteins.

Celulite/metabolismo , Disruptores Endócrinos/química , Exposição Ambiental , Hormônios/metabolismo , Compostos Benzidrílicos/química , Estrogênios/química , Homeostase , Humanos , Inflamação , Modelos Teóricos , Fenóis/química , Ácidos Ftálicos/química , Receptores Estrogênicos/metabolismo , Compostos de Trialquitina/química , Raios Ultravioleta
Acta pediatr. esp ; 76(5/6): e61-e63, mayo-jun. 2018. ilus
Artigo em Espanhol | IBECS | ID: ibc-177405


La sepsis tardía por Streptococcus agalactiae, o Streptococcus del grupo B (SGB), es una entidad que aparece entre los 7 días y 3 meses de edad y que suele manifestarse como bacteriemia/sepsis sin foco; no obstante, puede aparecer a modo de infección local, como en el caso del síndrome celulitis-adenitis. Se describen 2 casos clínicos en hermanos gemelos con aparición de sepsis tardía por SGB acompañado de síndrome celulitis-adenitis con un intervalo de separación de 3 semanas

Late-onset sepsis by Streptococcus agalactiae is an entity that appears between 7 days and 3 months of age and it usually manifests as bacteremia/sepsis without focus. However, it may appear as a local infection such as cellulitis-adenitis syndrome. Two clinical cases are described in twins with the occurrence of late-onset sepsis by group B Streptococcus (GBS) with cellulitis-adenitis syndrome in a time interval of 3 weeks

Humanos , Masculino , Recém-Nascido , Sepse Neonatal/diagnóstico , Doenças em Gêmeos/complicações , Antibacterianos/administração & dosagem , Celulite/diagnóstico , Linfadenite/diagnóstico , Sepse/diagnóstico , Infecções Estreptocócicas/diagnóstico , Sepse Neonatal/complicações , Streptococcus agalactiae/isolamento & purificação , Diagnóstico Tardio , Celulite/microbiologia , Linfadenite/microbiologia , Síndrome
Dermatol Surg ; 44(7): 949-963, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29846343


BACKGROUND: Ultrasound (US) technology uses acoustic waves to heat tissue, resulting in thermal damage and coagulative necrosis leading to the renewal of skin elasticity, body contouring, and destruction of cellulite. OBJECTIVE: This review will discuss the use of US for skin tightening, body contouring/sculpting, and cellulite reduction. MATERIALS AND METHODS: A literature search identified studies using US for skin tightening, body contouring/sculpting, and cellulite reduction. RESULTS: Two hundred thirty-one studies were identified using US technology. Twenty studies each were identified addressing body contouring/sculpting and skin tightening, and 2 studies for cellulite reduction. Ultrasound is efficacious for skin rejuvenation, body contouring, and reduction of cellulite of the face, décolletage, abdomen, and thighs. Ultrasound lipolysis results in a 2- to 4.6-cm decrease in abdominal circumference. Ultrasound is safe and can be used in all skin types with minimal concern for postinflammatory hyperpigmentation. CONCLUSION: Ultrasound seems to be an efficacious, effective, and safe modality for correction of skin laxity, lipolysis, and decrease the appearance of cellulite. Adverse effects are minimal including procedural pain, postprocedure erythema, and swelling. Clinicians and patients are both satisfied with results after treatment. In this review, the authors will provide an update on the use of US in the dermatologic field.

Contorno Corporal , Celulite/prevenção & controle , Dermatologia , Terapia por Ultrassom , Humanos
J Cosmet Dermatol ; 17(3): 361-364, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29524305


INTRODUCTION: This study investigates noninvasive cellulite treatments based on simultaneous application of monopolar radiofrequency (RF) and targeted pressure energy to evaluate efficacy and safety and to see whether simultaneous application has any benefits in noninvasive cellulite treatments. METHODS: Thirty women with cellulite (fibrous/adipose/aqueous types) received 4 gluteofemoral treatments (~24 minutes; ~1000 cm2 ) using a simultaneous application of RF and targeted pressure energy. Clinical improvement was assessed using a pentile grading scale and satisfaction questionnaires. Hip/thigh circumference was measured. Ultrasonography and thermography observed changes in dermal/subcutaneous tissue composition and in gluteofemoral thermal profile. Evaluation at 3 months posttreatment was compared against the baseline. RESULTS: The clinical improvement averaged 2.17 ± 0.95 (54% improvement). Cellulite was reduced in 93% of cases, while 73% of patients showed good/very good/excellent improvement, with most significant improvement seen in patients with moderately severe cellulite. Hips and thigh circumference decreased on average by 2.31 cm and 2.13 cm, respectively (P < .001). Patient satisfaction was very high, averaging 4.47 ± 0.57 points (1-5 scale). Ultrasonography revealed smoothing and thickening (+0.28 ± 0.15 mm) of the dermis and an average reduction of 1.96 ± 1.60 mm in fat thickness (P < .05). Subjects with significant cellulite reduction had a more homogenous thermal profile at follow-up as a result of therapy-induced diminution of topographic skin defects. No adverse events were recorded. CONCLUSION: The application is effective and safe for treating cellulite. The level of clinical improvement after 4 sessions is comparable to results reported after 6-20 sessions in studies on stand-alone RF/laser/targeted pressure energy devices. The technology is promising and deserves further attention and research.

Celulite/terapia , Técnicas Cosméticas , Ondas de Rádio/uso terapêutico , Som , Adulto , Celulite/diagnóstico por imagem , Terapia Combinada/efeitos adversos , Derme/diagnóstico por imagem , Feminino , Quadril , Humanos , Satisfação do Paciente , Ondas de Rádio/efeitos adversos , Som/efeitos adversos , Gordura Subcutânea/diagnóstico por imagem , Termografia , Coxa da Perna , Ultrassonografia
Drug Dev Ind Pharm ; 44(1): 158-171, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-28956468


Cellulite is a common topographical alteration where skin acquires an orange peel or mattress appearance with alterations in adipose tissue and microcirculation. This work aims to develop and evaluate a topical niosomal gel formulae with good permeation to reach the subcutaneous fat layer. Several caffeine niosomal dispersions were prepared and incorporated into gel formulae using Carbopol 940 polymer, chemical penetration enhancers, and iontophoresis, then the prepared gels were applied onto the skin of rats and anticellulite activity of caffeine from the prepared gels compared to that of the commercial product Cellu Destock® was evaluated by histological study of the skin and measurement of plasma level of caffeine passing through the skin using liquid chromatography (LC/MS-MS). Results of histology revealed reduction of size and thickness of fatty layer of rat skin in the following order: FVII > FXIV > Cellu Destock® > FVII + Iontophoresis > FXIV + Iontophoresis. Pharmacokinetic results of caffeine in plasma revealed that Cmax, Tmax, and AUC0-12h decreased in the following order: FXIV > FVII > Cellu Destock®. These results conclude that incorporation of caffeine niosomal dispersion into gel matrix with penetration enhancers and iontophoresis resulted in improvement in penetration of caffeine through the skin into the underlying fatty layer in treatment of cellulite.

Resinas Acrílicas/metabolismo , Tecido Adiposo/efeitos dos fármacos , Cafeína/administração & dosagem , Celulite/tratamento farmacológico , Géis/química , Iontoforese/métodos , Lipossomos/metabolismo , Tensoativos/metabolismo , Resinas Acrílicas/química , Resinas Acrílicas/farmacologia , Administração Cutânea , Animais , Cafeína/química , Química Farmacêutica , Sistemas de Liberação de Medicamentos , Ratos , Tensoativos/química
J Cosmet Dermatol ; 17(3): 448-453, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29205802


INTRODUCTION: Gynoid lipodystrophy, also known as cellulite, is a very common skin alteration representing mainly a cosmetic problem rather than a real disease. An effective treatment of cellulite has not been well established. The initial phase of cellulite is characterized by subdermal tissue edema with interstitial fluids retention. A new hypertonic topical product with draining action (HTC) containing NaCl 13%, escine, caffeine, and beta-sitosterol has been recently developed. A 28-day double-blind placebo-controlled study has shown that this cream is able to reduce thigh circumference and the thickness of adipose tissue. No data so far are available regarding an objective evaluation of skin appearance for a longer application period. STUDY AIM: To evaluate the clinical efficacy of 2-month HCT treatment with clinical and instrumental assessments. SUBJECTS AND METHODS: In a prospective, 2-center, assessor-blinded trial 20 women (mean age 34 years) with cellulite of Grade I-III in severity were enrolled after their informed consent. HTC was applied once daily for 60 days. Primary outcomes of the trial were the evolution of thigh circumference measurements (assessed at baseline, after 1 and 2 months) and the computer-analysis of skin profilometry (ie, skin volumes) of a prespecified target area evaluated by means of Antera 3D CS digitalized images (assessed at baseline and at the end of the trial). Secondary outcome was the orange peel severity score (from 0 to 5) before and after pitch test. RESULTS: All subjects concluded the study period. Thigh circumference was reduced by -0.88 (right)/-1.2 cm (left) and by -1.8(right)/-2.1 (left) cm, after 30 and 60 days of treatment, respectively (P = .001, Wilcoxon test vs baseline). Antera 3D profilometry of the target zone showed a significant reduction in skin depression expressed in mm3 of -56% (from 59.7 to 26.73 mm3 ) after HTC application. Orange peel (no pitch test) mean (SD) score was 2.3 (1) at baseline, 2.0 (1) and 1.8 (0.8) after 1 and 2 months (P = .0031), respectively. After-pitch orange peel score was significantly reduced after treatment (from 3.3 to 2.2). CONCLUSION: Once daily application of HTC for 2 months has confirmed its efficacy in the improvement of objective and subjective assessments of cellulite parameters.(Trial Number registration: ISRCTN15111614).

Celulite/tratamento farmacológico , Fármacos Dermatológicos/uso terapêutico , Adulto , Fármacos Dermatológicos/efeitos adversos , Feminino , Humanos , Estudos Prospectivos , Índice de Gravidade de Doença , Método Simples-Cego , Creme para a Pele , Coxa da Perna/anatomia & histologia
Clin Dermatol ; 36(1): 81-88, 2018 Jan - Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29241757


The cutaneous manifestations of obesity and the associated metabolic syndrome (MetS) may present with a wide variety of cutaneous findings, including acanthosis nigricans, acrochordon, cellulitis, psoriasis, hidradenitis suppurativa, acne, and hirsutism. Being aware of such clinical signs and the underlying systemic disorders may facilitate earlier diagnoses, thereby permitting earlier of therapy initiation and prevention of long-term sequelae. In this process, dermatologists are key figures in the early detection of MetS and its clinical manifestations.

Síndrome Metabólica/complicações , Obesidade/complicações , Dermatopatias/complicações , Acantose Nigricans/complicações , Adipose Dolorosa/complicações , Celulite/complicações , Dermatite Seborreica/complicações , Gota/complicações , Hidradenite Supurativa/complicações , Hirsutismo/complicações , Humanos , Hiperandrogenismo/complicações , Líquen Plano/complicações , Psoríase/complicações , Xantomatose/complicações
Fisioter. Bras ; 19(1): f:80-I:88, 2018.
Artigo em Português | LILACS | ID: biblio-910175


O microagulhamento é usado no tratamento de diversas afecções estéticas promovendo estímulo de colágeno. O objetivo deste trabalho foi averiguar a eficácia da associação do microagulhamento a fatores de crescimento e a vitamina C em diferentes afecções estéticas na região glútea. Foram realizadas 4 sessões de microagulhamento com intervalo de 21 dias entre as sessões. Percebeu-se significativa melhora na flacidez tissular, no fibro edema gelóide (FEG) e nas estrias e o microagulhamento mostrou-se uma técnica segura e eficaz para tratementos dessas disfunções estéticas. (AU)

The microneedling is used in the treatment of several aesthetic affections promoting collagen stimulation. The objective of this study was to verify the efficacy of the association of microneedling, growth factors and ascorbic acid in aesthetic affections in the gluteal region. Four sessions of microneedling were performed with a 21-day interval between the sessions, in which a significant improvement on skin laxity, cellulite and striae distensae was observed in the result and proved that the microneedling is to be a safe and effective technique for treating these aesthetic dysfunctions. (AU)

Humanos , Feminino , Celulite , Ácido Ascórbico , Dermatologia , Terapêutica
Rev. odontopediatr. latinoam ; 8(2): 112-122, 2018. tab
Artigo em Espanhol | LILACS, COLNAL | ID: biblio-999351


Objetivo: Determinar la prevalencia de complicaciones sistémicas derivadas de celulitis facial odontogénica y su relación con el peso y la talla de niños de 1 a 6 años hospitalizados en el Servicio de Infectología Pediátrica del Hospital Universitario de Caracas en el periodo 2006-2014. Materiales y métodos: Se realizó un estudio epidemiológico de prevalencia, no experimental, retrospectivo, transversal y analítico en una muestra seleccionada a conveniencia de 310 niños en edades entre 1 y 6 años, con análisis de frecuencias, porcentajes, promedios, prueba de significancia estadística chi cuadrado, correlación de Pearson y Odds-Ratio. Resultados: la prevalencia de complicaciones sistémicas derivadas de la celulitis facial odontogénica en esta muestra fue del 32%, y se reportan 5: meningitis 15%, absceso cerebral 2%, neumonía 6%, endocarditis infecciosa 5% y septicemia 4%. El 65,48% y el 68,06% de la muestra total presentó talla baja y peso bajo respectivamente. El peso bajo se relacionó estadísticamente con la presencia de complicaciones sistémicas en esta población. Al comparar con niños de talla y peso normal, los niños con baja talla (percentil 10) tuvieron una probabilidad 3 veces mayor de presentar complicaciones y los de bajo peso (percentil 10) presentaron 4 veces más probabilidades de presentar complicaciones sistémicas. Conclusiones: las complicaciones sistémicas que se pueden derivar de una celulitis facial odontogénica son varias y pueden comprometer la vida del paciente, en este estudio la más frecuente fue la meningitis. El peso y la talla son variables importantes a considerar al evaluar y tratar enfermedades infecciosas odontogénicas en la población pediátrica ya que pueden ser factores de riesgo en la aparición de complicaciones sistémicas asociadas.

Determinar a prevalência de complicações sistêmicas de celulite facial odontogenica e sua relação com o peso e altura de crianças de 1 a 6 anos hospitalizadas nas Serviço de Doenças Infecciosas Pediátricas del Hospital Universitário de Caracas, no período 2006-2014. Materiais e métodos. Um estudo epidemiológico de prevalência foi realizado, não-experimental, retrospectivo, transversal e analíticas em uma amostra de conveniência selecionada de 310 crianças de 1 a 6 anos, com análise de freqüência, porcentagens, médias, teste de shows de significância estatística chi quadrado, de correlação de Pearson e Odds ratio. Resultados. A prevalência de complicações sistémicas de celulite facial odontogénica nesta amostra foi de 32%, e relatou 5: 15% meningite, abcesso cerebral 2%, 6% pneumonia, endocardite infecciosa e septicemia 5% 4%. O 65,48% e ele 68,06% e a amostra total mostrou LHA e peso respectivamente. Baixo peso foi estatisticamente relacionada com a presença de complicações sistêmicas nesta população. Quando comparado com crianças de estatura normal e peso, crianças com baixa estatura (percentil 10) tinha 3 vezes mais propensos a ter complicações e baixo peso ao nascer (percentil 10) apresentou 4 vezes mais propensos a ter complicações Conclusões. Complicações sistémica que pode ser derivada a partir de celulite facial odontogénica são vários e podem comprometer a vida do paciente, no presente estudo o mais frequente foi a meningite. O peso e tamanho são variáveis importantes a considerar quando se avalia e tratamento de doenças infecciosas em pediátrica odontogénica população, pois podem ser factores de risco associados com o aparecimento de complicações sistémicas. Palavras-chave: celulite odontogenic facial, complicações sistêmicas, baixo peso, baixa estatura.

Aim: To determine the prevalence of systemic complications derived from odontogenic facial cellulitis and its relation to weight and height of children from 1 to 6 years hospitalized in the Pediatric Infectology Service of the University Hospital of Caracas in a period between 2006 and 2014. Materials and methods: An epidemiological and prevalence, non-experimental, retrospective, cross-sectional and analytical study was performed in convenience sample selected from 310 children aged 1 to 6 years. Data was analyzed by frequencies, percentages, averages, chi square test, Pearson correlation and Odds-Ratio. Results: The prevalence of systemic complications derived lofrom odontogenic facial cellulitis in this sample was 32% including: meningitis 15%, brain abscess 2%, pneumonia 6%, infective endocarditis 5% and septicemia 4%. 65.48% of the total sample presented low height and 68.06% low weight. Low weight was statistically related to the presence of systemic complications in this population. When compared with children of normal height and weight, children with low height (10th percentile) were 3 times more likely to present systemic complications and low weight children (10th percentile) 4 times higher chance for systemic complications. Conclusions: There are several systemic complications derived from an odontogenic facial cellulitis and can compromise the patient´s life. In this study the most frequent was meningitis. Weight and height are important variables to consider when evaluating and treating odontogenic infectious diseases in the pediatric population, since may constitute risk factors in the development of associated systemic complications.

Humanos , Criança , Odontodisplasia , Cárie Dentária/complicações , Infecção Focal Dentária , Celulite/complicações , Infecção/complicações , Meningite
Pesqui. vet. bras ; 37(12): 1395-1400, dez. 2017. tab, ilus
Artigo em Português | LILACS, VETINDEX | ID: biblio-895397


Celulite aviária é uma enfermidade de grande importância para a avicultura mundial, sendo relacionada principalmente à Escherichia coli (E. coli). Neste estudo foi comparada a susceptibilidade de duas linhagens de aves no desenvolvimento da celulite diante do desafio com diferentes concentrações de E. coli. Além disso, foi avaliada a relação dos genes iss e iutA com a patogenicidade de amostras de E. coli de diferentes origens (fecal/casos clínicos) em pintinhos e com a reprodução experimental da doença em aves de 35 dias de idade. Através da inoculação de frangos de corte (Cobb/Ross) com diferentes níveis de desafio (105 a 108 UFC/mL) de E. coli, não foram observadas diferenças significativas entre as linhagens quanto à sensibilidade à dermatite necrótica para a mesma dosagem (p≤0,05). A detecção dos genes iss e iutA demonstrou que estes estiveram presentes somente nas amostras provenientes de casos clínicos. Da mesma forma, estes isolados foram considerados de alta patogenicidade para pintinhos (>80% letalidade), levando a formação de áreas de lesão mais extensas (≥3cm2) em aves de 35 dias, quando comparado às amostras de origem fecal (p≤0,05). Ainda, as diferenças com relação ao tamanho de lesão foram constatadas também entre os isolados de mesma origem (p≤0,05). Desta forma, a linhagem não pode ser considerada um fator primordial para o desenvolvimento de dermatite necrótica em frangos. Ainda, sugere-se que os genes iss e iutA, quando presentes em conjunto ou isoladamente, poderiam ser considerados marcadores de virulência em cepas de E. coli causadoras de celulite aviária.(AU)

Avian cellulitis is a disease of great importance for the global poultry industry, being mainly related to Escherichia coli. In this study the susceptibility of two lineages of broilers in the development of cellulite was compared to the challenge with different concentrations of E. coli. In addition, it evaluated the relationship of the iss and iutA genes with pathogenicity of E. coli samples from different origins (fecal/clinical cases) in chicks and with the experimental reproduction of disease in 35-day-old broilers. By inoculating broilers (Cobb/Ross) with different levels of challenge (105-108 CFU/mL) of E. coli, no significant differences had been observed between strains for sensitivity to necrotic dermatitis for the same dosage (p≤0.05). Detection of the iss and iutA genes showed that they were only present in samples from clinical cases. Likewise, these strains were considered high pathogenicity for chickens (>80% lethality), leading to the formation of more extensive lesion areas (≥3cm2) at 35 days of birds compared to the samples from fecal origin (p≤0.05). Still, the differences with respect to lesion size were also found among isolates of the same origin (p≤0,05). Thus, the lineage can not be considered a primary factor in the development of necrotic dermatitis in broilers. Furthermore, it is suggested that iss and iutA genes, when present together or separately, could be considered as virulence markers for E. coli strains that cause avian cellulite.(AU)

Animais , Galinhas/genética , Fatores de Virulência/genética , Suscetibilidade a Doenças/veterinária , Escherichia coli/genética , Celulite/genética , Celulite/veterinária , Dermatite/veterinária
J Cosmet Laser Ther ; 19(7): 422-426, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-28678582


INTRODUCTION: Despite high incidence rate of cellulite, there are few studies regarding its treatment. Most of them present non-validated evaluation tools. Radio frequency is a focused treatment very used in aesthetics to reduce it. OBJECTIVES: To know the efficacy of Monopolar Dielectric Radio frequency (MDR) treatment in dynamic applications to reduce cellulite, panniculus adiposus and gluteal and posterior thigh regions. METHODS: Experimental study consisting of inferior members of nine women. They received 10 sessions based on dynamic applications of MDR. Variables included the following: Cellulite Severity Scale (CSS), appearance of the cutaneous area, flaccidity and ultrasound measurement of the panniculus adiposus. RESULTS: The final CSS score of the leg treated reflects statistically significative differences (p = 0.023) when compared with control leg (p = 0.622). Significant reductions of body perimeters at the level of the great trochanter (p = 0.02), the gluteal region (p = 0.03) and the midpoint of the posterior thigh (p = 0.01) are found. The reduction of the panniculus adiposus measured using ultrasound techniques shows significant changes in the midpoint of the posterior thigh (p = 0.028) as well as in the gluteal region (p = 0.03). CONCLUSIONS: The dynamic application of MDR seems to be effective in order to reduce not only the thickness of panniculus adiposus but also gluteal and posterior thigh perimeters.

Celulite/radioterapia , Técnicas Cosméticas , Ondas de Rádio/uso terapêutico , Gordura Subcutânea/efeitos da radiação , Adulto , Nádegas , Feminino , Humanos , Projetos Piloto , Índice de Gravidade de Doença , Gordura Subcutânea/diagnóstico por imagem , Coxa da Perna , Ultrassonografia , Adulto Jovem
J Cosmet Laser Ther ; 19(6): 320-324, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28590783


BACKGROUND: Cellulite affects the majority of women and is an unacceptable cosmetic defect. Therefore, effective methods for cellulite reduction are being sought. Intradermal mesotherapy is one of such methods. OBJECTIVE: The aim of the study was to assess the efficacy of intradermal mesotherapy in cellulite reduction, using conventional and high-frequency ultrasound. METHODS: Twenty-one women with cellulite underwent a series of intradermal mesotherapy procedures. The following parameters were assessed: thickness of epidermis, dermis and hypodermis, echogenicity of dermis and the surface area of serrated hypodermis-dermis junction. Furthermore, the thigh circumference was measured; body mass index and cellulite severity were assessed based on photographs using Nürnberger-Müller's scale. RESULTS: Intradermal mesotherapy reduced severity of cellulite. The surface area of serrated hypodermis-dermis junction and hypodermis thickness decreased significantly as compared to baseline. Cellulite reduction was also confirmed by palpation, decreased thigh circumference and the Nürnberger-Müller's grade. There were no statistically significant changes in epidermis or dermis thickness, body weight and the BMI. CONCLUSION: Intradermal mesotherapy offers effective cellulite reduction. It is a simple and safe treatment, which makes it popular. Further research in mesotherapy is essential due to a limited number of published studies. Ultrasound is a useful method to monitor intradermal mesotherapy and assess its efficacy.

Celulite/terapia , Técnicas Cosméticas , Mesoterapia/métodos , Ultrassonografia/métodos , Tecido Adiposo , Adulto , Índice de Massa Corporal , Derme , Epiderme , Feminino , Humanos , Injeções Intradérmicas , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Tela Subcutânea , Coxa da Perna