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1.
Niger J Clin Pract ; 23(4): 489-497, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32246655

RESUMO

Objective: This prospective study aimed to evaluate the clinical performance of different restorative materials in primary molars with class II carious lesions. Materials and Methods: A total of 160 class II carious lesions (with radiographic involvement of the outer half of dentin) in 30 patients were randomly divided into four groups and restored with a glass ionomer restorative system (Equia™), two different bulk-fill composites (Sonicfill™ and X-tra fil™), and a nanohybrid composite (Filtek Z550™). The restorations were clinically and radiographically evaluated at the baseline, and 3, 6, and 12 months according to the modified United States Public Health Service criteria. Statistical analyses were performed using Pearson's Chi-square and McNemar tests. Results: After 1 year, 134 restorations were evaluated in 26 patients. Equia was statistically less successful than the other restorative materials in marginal adaptation and retention criteria (P < 0.05). However, no material was found to be superior to the others over the study period in marginal discoloration, color matching, secondary caries, anatomical form, and postoperative sensitivity (P > 0.05). Conclusion: The bulk-fill and conventional composites exhibited good clinical performance, and Equia exhibited minor changes over the 1-year trial period.


Assuntos
Resinas Acrílicas , Resinas Compostas/uso terapêutico , Restauração Dentária Permanente/métodos , Cimentos de Ionômeros de Vidro/uso terapêutico , Dióxido de Silício , Adaptação Fisiológica , Biometria , Criança , Cor , Adaptação Marginal Dentária , Materiais Dentários , Dentina , Feminino , Seguimentos , Humanos , Masculino , Dente Molar , Período Pós-Operatório , Estudos Prospectivos , Dente Decíduo , Resultado do Tratamento
2.
Braz Oral Res ; 33: e125, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31994598

RESUMO

Atraumatic Restorative Treatment (ART) is one of the strategies used to control dental caries; it involves hand instruments for removal of carious tissue, and restorations using high-viscosity Glass Ionomer Cement (GIC). The present controlled clinical trial aimed to evaluate the performance of low-cost GIC indicated for ART in primary teeth, compared with high-viscosity GIC, after one year of follow-up. Two-to six-year-old children with dentin caries lesions on one or two surfaces of anterior and posterior teeth were selected. The children were randomly assigned to 2 groups according to the restorative material used: G1 (control) - Ketac Molar®; G2 (experimental) - Vitro Molar®. Treatments were performed in a school setting, following the guidelines of the ART. A total of 728 restorations were performed in 243 children. Descriptive analysis and Poisson regression were applied, with a significance level of p < 0.05. After 12 months, 559 (76.8%) restorations were re-evaluated. The success rate was evaluated by the prevalence ratio (PR), associated with restorations performed in primary second molars (PR = 1.21; 95%CI = 1.03-1.42), and with small (PR = 1.35; 95%CI = 1.14-1.60) or medium cavities (PR = 1.29; 95%CI = 1.08-1.55), using Ketac Molar® material (PR= 1.07; 95%CI = 1.01-1.15), considering p < 0.05. Small or medium restorations in primary second molars performed with high-viscosity GIC (Ketac Molar®) were more successful than restorations performed with low-cost GIC indicated for ART.


Assuntos
Tratamento Dentário Restaurador sem Trauma/métodos , Cárie Dentária/terapia , Cimentos de Ionômeros de Vidro/química , Criança , Pré-Escolar , Índice CPO , Falha de Restauração Dentária , Restauração Dentária Permanente/métodos , Feminino , Cimentos de Ionômeros de Vidro/uso terapêutico , Humanos , Masculino , Teste de Materiais , Distribuição de Poisson , Fatores de Tempo , Dente Decíduo , Resultado do Tratamento , Viscosidade
3.
Braz Oral Res ; 33: e099, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31778471

RESUMO

The aim of this clinical trial was to compare the 5-year cumulative survival of atraumatic restorative treatment restorations using high-viscosity glass-ionomer restorations (ART/HVGIC) and conventional resin composite restorations (CRT) placed in patients with intellectual and/or physical disability. Patients referred for restorative care to a special care service in Córdoba, Argentina, were recruited. Patients and/or caregivers were provided with written and verbal information regarding treatment options and selected the alternative they preferred. The treatment protocols were ART (hand instruments/HVGIC) in the clinic or CRT (rotary instrumentation/resin composite) in the clinic or under general anaesthesia (GA). Two independent, trained and calibrated examiners evaluated restoration survival using established ART codes after 6, 12, 24, 36 and 60 months. The proportional hazard model with frailty corrections provided survival estimates. Jackknife errors were used to test 5-year results. Sixty-six patients (13.6 ± 7.8 years) with 16 different medical conditions participated. CRT in the clinic proved feasible for five patients (13%), and 14 patients received CRT under GA (21%). ART was provided for 47 patients (71.2%). A total number of 298 dentine carious lesions were restored in primary and permanent teeth (182 ART; 116 CRT). Four patients died between the 3 and 5-year follow up. Percentage survival and jackknife standard error were calculated and were significantly higher for all ART/HVGIC restorations (90.2% ± 2.6) than for all CRT restorations (82.8% ± 5.3), 5 years after placement (p=0.044). These 5-year follow-up results confirm that ART/HVGIC is an effective treatment protocol for patients with disability, equal to that of conventional resin composite restoration. The results of this clinical trial support the use of ART as an evidence-based treatment resource contributing to the reduction of inequalities in access to oral health care among people with disability.


Assuntos
Resinas Compostas/uso terapêutico , Tratamento Dentário Restaurador sem Trauma/métodos , Restauração Dentária Temporária/métodos , Pessoas com Deficiência , Cimentos de Ionômeros de Vidro/uso terapêutico , Adolescente , Adulto , Criança , Pré-Escolar , Resinas Compostas/química , Falha de Restauração Dentária , Feminino , Seguimentos , Cimentos de Ionômeros de Vidro/química , Humanos , Masculino , Reprodutibilidade dos Testes , Fatores de Tempo , Resultado do Tratamento , Viscosidade , Adulto Jovem
4.
J Appl Oral Sci ; 27: e20180678, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31596369

RESUMO

OBJECTIVES: Bulk-fill restorative materials such as bulk-fill composite resins and high viscous glass ionomer cements have become very popular materials in operative dentistry because their application is easy and time-saving. The aim of this clinical study was to evaluate the clinical performance of a highly viscous reinforced glass ionomer material, a bulk-fill composite resin and a micro hybrid composite resin in Class II restorations. METHODOLOGY: In total, 109 Class II restorations were performed in 54 patients using three different restorative materials: Charisma Smart Composite (CSC); Filtek Bulk Fill Posterior Restorative (FBF); Equia Forte Fil (EF). Single Bond Universal adhesive (3M ESPE, Germany) was used with composite resin restorations. The restorations were evaluated using modified USPHS criteria in terms of retention, color match, marginal discoloration, anatomic form, contact point, marginal adaptation, secondary caries, postoperative sensitivity and surface texture. The data were analyzed using Chi-Square, Fischer's and McNemar's tests. RESULTS: At the end of one year, 103 restorations were followed up. No changes were observed during the first 6 months. At the end of one year, there were small changes in composite restorations (FBF and CSC) but no statistically significant difference was observed between the clinical performances of these materials for all criteria (p>0.05). However, there was a statistically significant difference between EF, FBF and CSC groups in all parameters except marginal discoloration, secondary caries and postoperative sensitivity in one-year evaluation (p<0.05). CONCLUSION: Bulk-fill composite resins and conventional composite resins showed more successful clinical performance than highly viscous reinforced glass ionomers in Class II cavities.


Assuntos
Resinas Compostas/uso terapêutico , Restauração Dentária Permanente/métodos , Cimentos de Ionômeros de Vidro/uso terapêutico , Adulto , Bis-Fenol A-Glicidil Metacrilato/uso terapêutico , Cárie Dentária/terapia , Adaptação Marginal Dentária , Feminino , Humanos , Masculino , Estudos Prospectivos , Reprodutibilidade dos Testes , Distribuição por Sexo , Resultado do Tratamento , Adulto Jovem
5.
J Dent ; 88: 103163, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-31276747

RESUMO

OBJECTIVES: Although there is some consensus that carious lesions in early stages (non-cavitated) could be treated using sealants, neither the type of materials nor their use in lesions with localized enamel breakdown (microcavitated) has been reported To compare the efficacy of resin or glass ionomer (GI) sealants in arresting microcavitated carious lesions (ICDAS 3) in first permanent molars. MATERIALS AND METHODS: A double-blinded randomized controlled clinical trial was conducted in 41 healthy 6 to 11-year-old children. At the baseline examination, each subject had at least one carious lesion classified as ICDAS 3 on the first permanent molar. One hundred fifty-one lesions were randomized into: Group 1: resin sealants (76 lesions) and Group 2: GI sealant (75 lesions). Carious lesion progression was assessed clinically and radiographically. Progression and retention failure were the outcomes used for group comparisons at p-value<0.05. RESULTS: After a two-year follow-up, only one lesion progressed to ICDAS 5, without statistically significant differences between the groups (χ2(1) = 0.90, p = 0.53). Radiographically, 100 lesions (98%) were arrested and 2 (2%) showed radiographic progression, without differences between groups (χ2(1) = 0.93, p = 0.93). At 2 years, complete retention was observed in 77% of the resin-based and in 83% of the GI sealants, without statistical differences between type of sealant (χ2(1) = 0.71, p = 0.48). The multilevel mixed model demonstrated that location and type of sealant did not affect retention rates (χ2(1) = 24,98, p < 0.001). CONCLUSION: Sealing ICDAS 3 carious lesions in permanent molars appears to be effective in arresting lesions after a two-year follow-up. Clinicaltrials.gov: RCTICDAS3/2015. CLINICAL SIGNIFICANCE: Minimally invasive approaches for carious lesion management have been promoted. Using sealants for the treatment of microcavitated lesions (ICDAS 3) appears predictable in the routine practice, without predilection for resin or glass ionomer materials. In addition to preserving tooth structure, this strategy reduces chair-time, dental fear and costs, and increases coverage to dental care.


Assuntos
Resinas Acrílicas/uso terapêutico , Cárie Dentária/prevenção & controle , Cimentos de Ionômeros de Vidro/uso terapêutico , Selantes de Fossas e Fissuras/uso terapêutico , Resinas Acrílicas/química , Criança , Resinas Compostas/química , Resinas Compostas/uso terapêutico , Método Duplo-Cego , Cimentos de Ionômeros de Vidro/química , Humanos , Dente Molar/patologia , Selantes de Fossas e Fissuras/química , Dióxido de Silício
6.
Clin Biomech (Bristol, Avon) ; 62: 66-71, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30703691

RESUMO

BACKGROUND: Cerclage wires remain the current standard of care following median sternotomy, despite significant complications including dehiscence and infection. This study uses a human cadaveric model to investigate the use of glass polyalkenoate cements formulated from two glasses, A (mole fraction: SiO2:0.48, ZnO:0.36, CaO:0.12, SrO:0.04) and B (mole fraction: SiO2:0.48, ZnO:0.355, CaO:0.06, SrO:0.08, P2O5:0.02, Ta2O5:0.005), to improve wired sternal fixation. METHODS: Median sternotomies were performed on fifteen cadaveric sterna. Fixation was performed with either traditional wire cerclage or adhesive-enhanced wire cerclage; the adhesive based on either Glass A or Glass B. Cyclic tensile loading of 10 N to 100 N was applied. Every 30 cycles, the maximum load was increased by 100 N up to a maximum of 500 N. Two adhered sterna were tested beyond 500 N. Mid-sternal displacement was measured to assess fixation stability. FINDINGS: Displacement for adhesive-enhanced sternal closures were significantly less (p < 0.05) than standard wire cerclage. There was no significant difference between adhesives. Up to 500 N, no adhesive-enhanced sternum experienced a pathological sternal displacement (>2 mm), while three out of five of traditional wire fixations did. Of the two adhered samples tested beyond 500 N, one showed pathological displacement at 800 N and the other at 1100 N. Failure of adhered sterna appeared to initiate within the trabecular bone rather than in the adhesive. INTERPRETATION: The adhesives were capable of providing immediate bone stability, significantly reducing sternal displacement. In vivo investigations are warranted to determine the effect the adhesives have on bone remodelling.


Assuntos
Adesivos/uso terapêutico , Cimentos de Ionômeros de Vidro/uso terapêutico , Esternotomia , Esterno/cirurgia , Procedimentos Cirúrgicos Torácicos/métodos , Idoso , Cadáver , Humanos , Masculino , Pessoa de Meia-Idade
7.
J Indian Soc Pedod Prev Dent ; 37(1): 60-66, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30804309

RESUMO

Background: Indirect pulp therapy (IPT) is conventional treatment of deep dentinal carious lesions without risk of pulp exposure. Development of new biomaterials with biocompatibility and seal has changed the attitudes toward IPT. Aim/Objectives: This study was conducted to evaluate and compare the clinical and radiographic success of biodentine, 2% chlorhexidine gluconate with resin-modified glass ionomer cement (RMGIC), and calcium hydroxide as indirect pulp-capping materials in primary molars over an observation period of 12 months. Materials and Methods: A total of 54 primary molars within the age group of 3-9 years, which were indicated for IPT were randomized into three groups of 18 samples each; Group I: biodentine, Group II: 2% chlorhexidine gluconate followed by RMGIC, Group III: calcium hydroxide (Dycal). These cases were followed up for evaluation clinically and radiographically at 3, 6, and 12 months. The recorded data were subjected to statistical analysis using Chi-square test. Results: After 12 months, the clinical and radiographic success of biodentine group was 100% (18/18), with 2% chlorhexidine gluconate disinfecting solution followed by RMGIC was 94.4% (17/18) and calcium hydroxide (Dycal) was 94.4% (17/18), failures included one at 3 months with RMGIC and another at 12 months with calcium hydroxide group; but there was no statistically significant difference observed between them with P = 0.361 at 3 months and P = 0.371 at 12 months interval. Conclusion: Biodentine can be effectively used as indirect pulp-capping medicament in primary teeth which has similar clinical and radiographic success as 2% chlorhexidine gluconate in conjunction with RMGIC and calcium hydroxide.


Assuntos
Compostos de Cálcio/uso terapêutico , Hidróxido de Cálcio/uso terapêutico , Clorexidina/uso terapêutico , Cimentos de Ionômeros de Vidro/uso terapêutico , Dente Molar/efeitos dos fármacos , Agentes de Capeamento da Polpa Dentária e Pulpectomia/uso terapêutico , Cárie Radicular/tratamento farmacológico , Silicatos/uso terapêutico , Dente Decíduo/efeitos dos fármacos , Criança , Pré-Escolar , Clorexidina/administração & dosagem , Humanos
8.
BMC Oral Health ; 19(1): 6, 2019 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-30621659

RESUMO

BACKGROUND: Due to the lack of evidence to determine the best treatment for deep cavitated caries lesions in primary molars, the search for an effective restorative technique, which results in a minimal discomfort to patients, and reduce the time needed for the treatment, becomes relevant. The objective of this randomized clinical trial was to evaluate if high-viscosity glass ionomer cement (HVGIC) restorations is noninferior to restoration with calcium hydroxide cement associated with HVGIC for treatment of deep lesions in primary molars, as well as the impact of the treatments on cost and discomfort of the patient. METHODS: A non-inferiority randomized clinical trial with two parallels arms (1:1) will be conducted. Children with 4 to 8 years will be selected at Clinic of Pediatric Dentistry at Ibirapuera University. 108 teeth will be randomized into two groups: (1) Calcium hydroxide cement associated with HVGIC and (2) HVGIC restoration. Primary outcome will be considered the pulp vitality and to be evaluated after 6, 12, 18 and 24 months by two calibrated examiners. Survival of restorations will also be evaluated in the equal intervals. The duration of dentals treatment and the cost of all materials used will be considered for estimating of cost-efficacy of each treatment. Individual discomfort will be measured after each dental procedure using the Wong-Baker's Facial Scale. For the primary outcome, Kaplan-Meier survival and the long-rank test will be used to comparison between the groups. Cox regression will be performed to assess the influence of variables on the outcome. For all analyzes, the significance level is set at 5%. DISCUSSION: Based on the philosophy of ART, our hypothesis is that the HVGIC restoration is a possible approach to restore the deep caries lesion with pulp vitality without the use of rubber dam and anesthesia. TRIAL REGISTRATION: Clinicaltrials.gov registration NCT02903979 . Registered on June 9th 2016.


Assuntos
Assistência Odontológica para Crianças/métodos , Cárie Dentária/reabilitação , Restauração Dentária Permanente/métodos , Cimentos de Ionômeros de Vidro/uso terapêutico , Dente Decíduo , Resinas Acrílicas , Criança , Coroas , Cárie Dentária/prevenção & controle , Cimentos Dentários , Método Duplo-Cego , Humanos , Dente Molar , Avaliação de Resultados em Cuidados de Saúde , Odontopediatria , Dióxido de Silício
9.
J Prosthodont ; 28(2): e705-e712, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29522263

RESUMO

PURPOSE: To evaluate the biocompatibility of five dental cement compositions after directly exposing human gingival fibroblast (HGF) and MC3T3-E1 preosteoblast cells to cement alone and cement applied on commercially pure titanium (cpTi) specimens. MATERIALS AND METHODS: Nanostructurally integrated bioceramic (NIB), resin (R), resin-modified glass ionomer (RMGIC), zinc oxide eugenol (ZOE), and zinc phosphate (ZP) compositions were prepared according to the respective manufacturer's instructions. Samples were prepared in cylindrical Teflon molds or applied over the entire surface of polished cpTi discs. All samples were cured for 0.5, 1, 12, or 24 hours post-mixing. Direct contact testing was conducted according to ISO 10993 by seeding 6-well plates at 350,000 cells/well. Plates were incubated at 37°C in a humidified atmosphere with 5% CO2 for 24 hours before individually plating samples and cpTi control discs. Plates were then incubated for an additional 24 hours. Microtetrazolium (MTT) cell viability assays were used to measure sample cytotoxicity. RESULTS: For samples that cured for 24 hours prior to direct contact exposure, only NIB and ZP cements when cemented on cpTi demonstrated cell viability percentages above the minimum biocompatibility requirement (≥70%) for both the investigative cell lines. R, RMGIC, and ZOE cements exhibited moderate to severe cytotoxic effects on both cell lines in direct contact and when cemented on cpTi specimens. For HGF cells, ZOE cemented-cpTi specimens exhibited significantly decreased cytotoxicity, whereas RMGIC cemented-cpTi specimens exhibited significantly increased cytotoxicity. CONCLUSIONS: Despite previous studies that showed enhanced cpTi corrosion activity for fluoride-containing compositions (NIB and ZP), there was no significant difference in cytotoxicity between cement alone and cemented-cpTi. In general, the MC3T3-E1 preosteoblast cells were more sensitive than HGF cells to cement composition. Ultimately, cement composition played a significant role in maintaining host cell compatibility. Results of this work help illustrate the impact of different cement formulations on host cell health and emphasize the need for understanding material properties when selecting certain formulations of dental cements, which can ultimately influence the survival of dental implant systems.


Assuntos
Materiais Biocompatíveis , Cimentos Dentários/uso terapêutico , Implantes Dentários , Titânio , Sobrevivência Celular/efeitos dos fármacos , Cerâmica/uso terapêutico , Retenção em Prótese Dentária/métodos , Fibroblastos , Gengiva/citologia , Cimentos de Ionômeros de Vidro/uso terapêutico , Humanos , Técnicas In Vitro , Teste de Materiais/métodos , Nanoestruturas/uso terapêutico , Cimento de Óxido de Zinco e Eugenol/uso terapêutico , Cimento de Fosfato de Zinco/uso terapêutico
10.
Caries Res ; 53(1): 24-32, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-29874642

RESUMO

OBJECTIVES: To investigate whether silver diamine fluoride (SDF) is effective in preventing new caries lesions in primary teeth when compared to placebo or active treatments. METHODS: Systematic review (CRD42016036963) of controlled clinical trials. Searches were performed in 9 electronic databases, 5 registers of ongoing trials, and reference lists of identified review articles. Two researchers carried out data extraction and quality appraisal independently. The primary outcome was the difference in caries increment (decayed, missing, and filled surfaces or teeth - dmfs or dmft) between SDF and control groups. These differences were pooled as weighted mean differences (WMD) and prevented fractions (PF). RESULTS: Searches yielded 2,366 unique records; 6 reports of 4 trials that randomized 1,118 and analyzed 915 participants were included. Two trials compared SDF to no treatment, 1 compared SDF to placebo and sodium fluoride varnish (FV), and 1 compared SDF to high-viscosity glass ionomer cement (GIC). All studies had at least 1 domain with unclear or high risk of bias. After 24 months of follow-up, in comparison to placebo, no treatment, and FV, SDF applications significantly reduced the development of new dentin caries lesions (placebo or no treatment: WMD = -1.15, PF = 77.5%; FV: WMD = -0.43, PF = 54.0%). GIC was more effective than SDF after 12 months of follow-up but the difference between them was not statistically significant (WMD, dmft: 0.34, PF: -6.09%). CONCLUSION: When applied to caries lesions in primary teeth, SDF compared to no treatment, placebo or FV appears to effectively prevent dental caries in the entire dentition. However, trials specifically designed to assess this outcome are needed.


Assuntos
Cariostáticos/uso terapêutico , Cárie Dentária/tratamento farmacológico , Cárie Dentária/prevenção & controle , Compostos de Amônio Quaternário/uso terapêutico , Compostos de Prata/uso terapêutico , Dente Decíduo/fisiologia , Cariostáticos/efeitos adversos , Criança , Pré-Escolar , Ensaios Clínicos Controlados como Assunto , Fluoretos Tópicos/efeitos adversos , Fluoretos Tópicos/uso terapêutico , Seguimentos , Cimentos de Ionômeros de Vidro/efeitos adversos , Cimentos de Ionômeros de Vidro/uso terapêutico , Humanos , Inflamação/etiologia , Compostos de Amônio Quaternário/efeitos adversos , Compostos de Prata/efeitos adversos , Fluoreto de Sódio/efeitos adversos , Fluoreto de Sódio/uso terapêutico , Distúrbios do Paladar/etiologia , Descoloração de Dente/etiologia
11.
J Prosthodont ; 28(1): 85-90, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29508472

RESUMO

PURPOSE: To determine the effect of changing the dispensing or mixing method of resin-modified glass ionomer (RMGI) cements on their water sorption, solubility, film thickness, and shear bond strength. MATERIALS AND METHODS: Disc-shaped specimens of RMGI cements (RelyX: Luting [handmix], Luting Plus [clicker-handmix], Luting Plus [automix], GC: Fuji PLUS [capsule-automix], FujiCEM 2 [automix], [n = 10]) were prepared according to ISO standard 4049 for water sorption and solubility tests. Furthermore, the percentage of mass change, percentage of solubility, and percentage of water absorbed was also determined. Film thickness was measured according to ISO standard 9917-2; the mean of 5 measurements for each cement was calculated. Shear bond strength for each cement was determined according to ISO standard 29022 before and after thermocycling at 20,000 cycles, temperatures 5 to 55°C with a 15-second dwell time (n = 10/subgroup). Two- and one-way ANOVA were used to analyze data for statistical significance (p < 0.05). RESULTS: Water sorptions of the RMGI cements were in close range (214-250 µg/mm3 ) with no statistical differences between counterparts (p > 0.05). RelyX Luting Plus (clicker-handmix) displayed lower solubility than its handmix and automix counterparts (p < 0.05). Film thickness of RelyX cements was significantly different (p < 0.05). RelyX Luting Plus (automix) had the lowest film thickness (19 µm) compared to its handmix (48 µm) and clicker-handmix (117 µm) counterparts (p < 0.05). GC Fuji PLUS (capsule-automix, 22 µm) was significantly lower than the automix version (GC FujiCEM 2, 127 µm) (p < 0.05). Shear bond strength of RelyX Luting Plus (automix) was significantly lower than its handmix and clicker-handmix versions (p < 0.05). GC Fuji PLUS (capsule-automix) was significantly higher than GC FujiCEM 2 (automix) (p < 0.05). The binary interaction of the two independent variables (dispensing/mixing method and thermocycling) was significant for the shear bond strengths of the GC cements only (p < 0.05). CONCLUSIONS: Change in the dispensing/mixing method of RMGI cement from the same brand may have an effect on its physical properties, in addition to its film thickness and shear bond strength. Newer, easier, and faster cement delivery systems are not necessarily better. Clinical outcomes of these differences are yet to be confirmed.


Assuntos
Colagem Dentária/métodos , Cimentos de Ionômeros de Vidro/uso terapêutico , Resinas Compostas/uso terapêutico , Análise do Estresse Dentário , Humanos , Resistência ao Cisalhamento
12.
Dental Press J Orthod ; 23(5): 58-64, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30427494

RESUMO

INTRODUCTION: The number of patients who seek orthodontic treatment that may have a history of tooth bleaching is increasing over the time. Bleaching may influence the decrease of the bond strength of orthodontic brackets. OBJECTIVE: To determine and prove the effect of mangosteen peel (MP) extract to reverse the reduced shear bond strength (SBS) of orthodontic brackets after bleaching. METHODS: A total of 150 maxillary first premolar teeth were randomly divided into 6 experimental groups as follow (n=25): negative-control (N: no bleaching), positive-control (P: bleaching + no treatment), and the treatment groups (bleaching + 10% sodium ascorbate (SA), 10% (MP-10), 20% (MP-20) and 40% (MP-40) MP extract gel). After treatment, the brackets were bonded with the resin-modified glass ionomer cement, SBS testing was performed using universal testing machine, and the adhesive remnant index (ARI) was examined using stereoscopic microscope after debonding. The SBS data were analyzed by analysis of variance (Anova) and the Tukey test. For the ARI, the Kruskal-Wallis test was performed. RESULT: There was significant SBS difference (p< 0.001) between various groups. The group without bleaching showed significantly higher SBS (8.19 ± 2.26 MPa) compared to others, while SBS in the group treated with 40% MP gel was significantly higher (7.93 ± 1.92 MPa) than other groups treated with antioxidants. The failure of orthodontic brackets bonded after bleaching and treatment using MP extract occurred at the enamel-adhesive interface. CONCLUSION: The application of MP extract as an antioxidant after bleaching was effective in reversing the reduced shear bond strength of orthodontic brackets after bleaching.


Assuntos
Antioxidantes/efeitos adversos , Frutas/efeitos adversos , Garcinia mangostana/efeitos adversos , Braquetes Ortodônticos , Extratos Vegetais/efeitos adversos , Resistência ao Cisalhamento/efeitos dos fármacos , Clareamento Dental , Colagem Dentária , Análise do Estresse Dentário , Cimentos de Ionômeros de Vidro/uso terapêutico , Humanos , Clareamento Dental/efeitos adversos
13.
Oral Health Prev Dent ; 16(5): 417-424, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30460354

RESUMO

PURPOSE: In this study, the protective effects of restorative materials with fluoride content, resin-modified glass-ionomer cement (RMGIC), giomer, and glass carbomer against artificial initial caries lesions in a simulated highly cariogenic oral environment were evaluated. Considering the reported recharging abilities of these restorative materials, fluoridated toothpaste was applied to some groups, in which the anti-demineralising effect was also evaluated. MATERIALS AND METHODS: Two enamel blocks were produced from each of 60 sound permanent molars. Sixty specimens were used for microhardness analysis, and the rest were used for SEM-EDX analysis. Enamel specimens were randomly assigned to three groups according to the restorative material: A = resin-modified glass-ionomer cement; B = giomer; C = glass carbomer. Artificial initial caries lesions were created using demineralising solutions, after which specimens were exposed to in vitro pH cycling simulating a highly cariogenic oral environment. Microhardness and mineral analyses were performed on the enamel surrounding the restorative materials at three different times during the experiment: at the beginning of the experiment, then after the creation of the artificial early caries lesions, and finally after pH cycling. RESULTS: Microhardness and SEM-EDX results mostly confirmed each other. RMGIC and glass carbomer groups with added fluoride toothpaste showed statitsically significantly better anti-demineralising effects in comparison to other groups. Neither of the giomer groups performed as well as RMGIC or glass carbomer. CONCLUSION: Because of the similarity between the demineralisation inhibitory activity of glass carbomer and RMGIC, glass carbomer may be preferred as a restorative material in paediatric dentistry.


Assuntos
Apatitas/uso terapêutico , Cariostáticos/uso terapêutico , Cárie Dentária/terapia , Esmalte Dentário/ultraestrutura , Fluoretos/uso terapêutico , Cimentos de Ionômeros de Vidro/uso terapêutico , Dureza , Cimentos de Resina/uso terapêutico , Esmalte Dentário/diagnóstico por imagem , Materiais Dentários/uso terapêutico , Humanos , Técnicas In Vitro , Microscopia Eletrônica de Varredura , Espectrometria por Raios X , Cremes Dentais/uso terapêutico
14.
J Dent Child (Chic) ; 85(2): 75-78, 2018 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-30345957

RESUMO

Langerhans cell histiocytosis (LCH) is a rare disease characterized by abnormal proliferation of bone marrow-derived histiocytes (Langerhans cells). LCH may manifest orally with single or multiple lesions of the alveolar or basal bone. Ulcerated mucosal lesions may be accompanied by periodontal lesions that present with gingival inflammation, bleeding, recession, necrosis, toothache, dental hypermobility, tooth development abnormalities, and premature tooth loss. This paper presents the case of a five-month-old boy with very early oral manifestations of LCH and describes the combined systemic and dental treatment during a 36-month follow-up. A combined local and systemic approach may be necessary to control oral disease manifestations.


Assuntos
Histiocitose de Células de Langerhans/diagnóstico , Histiocitose de Células de Langerhans/terapia , Doenças da Boca/diagnóstico , Doenças da Boca/terapia , Citarabina/uso terapêutico , Quimioterapia Combinada , Seguimentos , Cimentos de Ionômeros de Vidro/uso terapêutico , Histiocitose de Células de Langerhans/tratamento farmacológico , Humanos , Imunossupressores/uso terapêutico , Lactente , Masculino , Mercaptopurina/uso terapêutico , Metotrexato/uso terapêutico , Doenças da Boca/tratamento farmacológico , Prednisona/uso terapêutico , Vimblastina/uso terapêutico
15.
Trials ; 19(1): 523, 2018 Sep 26.
Artigo em Inglês | MEDLINE | ID: mdl-30257696

RESUMO

BACKGROUND: Dental caries is the most prominent childhood disease in the world. In the United States, more than 50% of children have experienced caries. Untreated caries can have negative impacts on quality of life, academic performance, and school attendance. To reduce oral health disparities, multiple organizations recommend school-based caries prevention. METHODS/DESIGN: A longitudinal, cluster randomized, non-inferiority trial will be conducted in low-income children from primarily Hispanic/Latino backgrounds currently enrolled in public elementary schools in New York City, New York, United States, from 2018 to 2023. The primary objective is to compare the non-inferiority of silver diamine fluoride and fluoride varnish versus glass ionomer therapeutic sealants and fluoride varnish in the arrest and prevention of dental caries. Secondary objectives are to evaluate differences in effectiveness when care is provided by nurses versus dental hygienists and assess the impact of prevention on oral health-related quality of life and educational outcomes. Caries arrest will be evaluated after 2 years, and caries prevention and secondary outcomes will be assessed at the completion of the study. Data analysis will follow intent-to-treat, and statistical analyses will be conducted using a two-sided significance level of 0.05. DISCUSSION: The comparative effectiveness of alternative caries prevention delivery models is considered to be one of the highest research priorities in the United States. Many treatments are currently available to prevent and arrest dental caries. The simplicity and affordability of silver diamine fluoride may be a viable alternative for the prevention of dental caries in high-risk children. TRIAL REGISTRATION: U.S. National Library of Medicine, www.clinicaltrials.gov , ID: NCT03442309 . Registered on 22 February 2018.


Assuntos
Assistência Odontológica para Crianças/métodos , Cárie Dentária/prevenção & controle , Cimentos de Ionômeros de Vidro/uso terapêutico , Grupos Minoritários , Saúde das Minorias , Selantes de Fossas e Fissuras/uso terapêutico , Pobreza , Compostos de Amônio Quaternário/uso terapêutico , Serviços de Odontologia Escolar/métodos , Compostos de Prata/uso terapêutico , Fatores Etários , Criança , Pré-Escolar , Cárie Dentária/diagnóstico , Cárie Dentária/etnologia , Estudos de Equivalência como Asunto , Feminino , Fluoretos Tópicos/uso terapêutico , Humanos , Estudos Longitudinais , Masculino , Cidade de Nova Iorque/epidemiologia , Ensaios Clínicos Pragmáticos como Assunto , Fatores de Tempo , Resultado do Tratamento
16.
Implant Dent ; 27(5): 582-587, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30134265

RESUMO

PURPOSE: To evaluate Ti-Base abutment height and cement type on the retentiveness of zirconia-based restorations. MATERIAL AND METHODS: Four millimeter (tall) and 2.5-mm-height (short) abutments along with temporary (provisional), glass ionomer (Meron), self-adhesive (U200), and conventional resin cement (Ultimate) were evaluated using pull-out testing (n = 10 crowns/group). RESULTS: Tall and short abutments demonstrated similar retention for all within cement comparisons, except U200 (P = 0.032). Resin cements exhibited superior retentiveness than others (P < 0.01). Although no significant difference was evidenced between resin cements for short abutments, Ultimate evidenced higher retention than U200 for tall abutments (P = 0.043). CONCLUSIONS: Although Ti-Base abutment height has not influenced zirconia superstructures' retentiveness, resin-based cements significantly evidenced higher retention than glass ionomer and temporary cements.


Assuntos
Desenho Assistido por Computador , Coroas , Dente Suporte , Cimentos Dentários/uso terapêutico , Projeto do Implante Dentário-Pivô , Planejamento de Prótese Dentária , Zircônio , Planejamento de Prótese Dentária/métodos , Restauração Dentária Permanente/métodos , Análise do Estresse Dentário , Cimentos de Ionômeros de Vidro/uso terapêutico , Humanos , Cimentos de Resina/uso terapêutico
17.
Eur J Paediatr Dent ; 19(3): 247-249, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30063160

RESUMO

Determining the best choice between the different sealant materials might be complicated. The products that dentists can choose have different properties, such as caries' preventive effect, fluoride release and retention rate. According to the literature, fissure sealant materials fall into two main categories: resin-based sealants and glass ionomer sealants. Even if the "fluoride-releasing resin sealants" are better than "glass ionomer", with regards to retention of the material, the literature shows that their effectiveness in preventing fissure caries in permanent molars does not differ significantly over 24 months.


Assuntos
Cárie Dentária/prevenção & controle , Selantes de Fossas e Fissuras/química , Selantes de Fossas e Fissuras/uso terapêutico , Resinas Acrílicas/química , Resinas Acrílicas/uso terapêutico , Criança , Cimentos de Ionômeros de Vidro/química , Cimentos de Ionômeros de Vidro/uso terapêutico , Humanos
18.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 53(7): 437-442, 2018 Jul 09.
Artigo em Chinês | MEDLINE | ID: mdl-29996359

RESUMO

Objective: To evaluate and compare the caries prevention effectiveness of a resin-based sealant and a glass ionomer sealant on permanent first molars in 7- to 9-years-old school children. Methods: A randomized controlled, examiner-blinded, 5-year clinical trial was conducted in 19 primary schools in Dalian, Liaoning province. Totally 419 children (with 664 first molars) who had at least one sound permanent first molar with deep fissures or fissures with signs of non-cavitated lesions were recruited and stratified and allocated randomly into three parallel groups. A resin-based sealant was used in Group R (136 children with 219 first molars) and a glass ionomer sealant was used in Group G (130 children with 218 first molars). The third group (Group N, 153 children with 227 first molars) with none of the two sealants applied was served as blank control. Follow-up examinations were conducted at 0.5, 1, 2, and 5 years after sealing in order to assess the retention of the sealants and the incidence of caries occurrence. Chi-square test was adopted to compare the differences of caries incidence among the 3 groups. Generalized estimating equations (GEE) was used to analyze the effective factors of caries incidence. Results: During the 5-year follow-up period, 13.4% (23/172) of the teeth in Group R, 22.5% (40/178) of the teeth in Group G and 34.5% (57/165) of the teeth in Group N were diagnosed as having developed cavitated lesions. And the differences in the incidence of caries among the three groups was statistically significant (P<0.05). According to GEE, the resin-based sealant and the glass ionomer sealant were found to be the protection factors and the non-cavitated lesion before sealing was found to be the risk factor. The resin-based sealant was found to be the protection factor to the glass ionomer sealant when the blank control group was removed. Conclusions: Both resin-based sealant and glass ionomer sealant could effectively prevent the permanent first molars from the occurrence of carious lesions in 5 years. The resin-based sealant was superior to the glass ionomer sealant in caries prevention.


Assuntos
Resinas Acrílicas/uso terapêutico , Cárie Dentária/prevenção & controle , Cimentos de Ionômeros de Vidro/uso terapêutico , Selantes de Fossas e Fissuras/uso terapêutico , Dióxido de Silício/uso terapêutico , Criança , Seguimentos , Humanos , Dente Molar , Fatores de Tempo
19.
Cell Stress Chaperones ; 23(6): 1337-1343, 2018 11.
Artigo em Inglês | MEDLINE | ID: mdl-29876727

RESUMO

Candida albicans causes opportunistic fungal infections usually hidden among more dominant bacteria and does not exhibit high pathogenicity in vivo. Among the elderly, due to reduced host resistance to pathogens attributable to immunoscenesence, oral candidiasis is more likely to develop often leading to systemic candidiasis. Surface pre-reacted glass ionomer filler (S-PRG filler) is an ion-releasing functional bioactive glass that can release and recharge six ions which in turn strengthens tooth structure, inhibits demineralization arising from dental caries, and suppresses dental plaque accumulation. However, its effects on C. albicans have never been elucidated. Here, we evaluated the effects of ion released from S-PRG filler on C. albicans. Results show that extraction liquids containing released ions (ELIS) decreased the amount of hydrogen peroxide and catalase activity in C. albicans. Moreover, ELIS presence was found to affect C. albicans: (1) suppression of fungal growth and biofilm formation, (2) prevent adherence to denture base resin, (3) inhibit dimorphism conversion, and (4) hinder the capability to produce secreted aspartyl proteinase. Taken together, our findings suggest that ELIS induces oxidative stress in C. albicans and suppresses its growth and pathogenicity. In this regard, we propose that ELIS has the potential to be clinically used to help prevent the onset and inhibition of oral candidiasis among the elderly population.


Assuntos
Resinas Acrílicas/farmacologia , Biofilmes/efeitos dos fármacos , Candida albicans/efeitos dos fármacos , Candidíase Bucal/prevenção & controle , Cimentos de Ionômeros de Vidro/farmacologia , Dióxido de Silício/farmacologia , Resinas Acrílicas/química , Resinas Acrílicas/uso terapêutico , Idoso , Ácido Aspártico Proteases/metabolismo , Candida albicans/crescimento & desenvolvimento , Candida albicans/patogenicidade , Catalase/antagonistas & inibidores , Adesão Celular/efeitos dos fármacos , Bases de Dentadura/microbiologia , Cimentos de Ionômeros de Vidro/química , Cimentos de Ionômeros de Vidro/uso terapêutico , Humanos , Íons/química , Íons/farmacologia , Íons/uso terapêutico , Estresse Oxidativo , Dióxido de Silício/química , Dióxido de Silício/uso terapêutico
20.
Gen Dent ; 66(3): 32-36, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29714697

RESUMO

This in vitro study evaluated the marginal microleakage of a bioactive restorative with other restorative materials in standard Class V preparations. Sixty previously extracted, noncarious human molars were randomly assigned to 3 experimental groups (n = 20): a bioactive composite resin, a universal hybrid composite resin, and a resin-modified glass ionomer restorative. Class V cavities were prepared on the facial or lingual surface of each tooth so that coronal margins were located in enamel and apical margins in cementum (dentin). After the cavity preparations were restored with the appropriate material, the specimens were artificially aged in water baths. The root apices were sealed with utility wax, the tooth surfaces were coated with nail varnish to within 1 mm of the restoration, and specimens were immersed in 1% methylene dye solution for 8 hours. The teeth were invested in clear polymer resin, sectioned longitudinally, and examined under a stereomicroscope to assess dye penetration. Nonparametric scores indicated that microleakage was significantly greater at the apical margins than the coronal margins for all groups (P > 0.0001). The specimens restored with the bioactive material exhibited greater microleakage at both the coronal and apical margins than did specimens restored with the composite resin or resin-modified glass ionomer material, although the differences were not statistically significant (P > 0.05). Based on the results of the present study, the type of restorative material did not appear to have a significant influence on microleakage. Rather, the marginal position (coronal versus apical) of the restoration was the determining factor in microleakage.


Assuntos
Adaptação Marginal Dentária , Restauração Dentária Permanente/métodos , Resinas Compostas/uso terapêutico , Cárie Dentária/cirurgia , Preparo da Cavidade Dentária/métodos , Infiltração Dentária/etiologia , Cimentos de Ionômeros de Vidro/uso terapêutico , Humanos , Técnicas In Vitro
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