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1.
Autops. Case Rep ; 9(3): e2019095, July-Sept. 2019. ilus
Artigo em Inglês | LILACS | ID: biblio-1021055

RESUMO

Dermoid cyst (DC) is a cystic lesion of developmental origin and uncertain etiology that rarely affects the floor of the mouth. We report a case of a large lesion found in the submental and submandibular region in a 25-year-old male patient. Computed tomography revealed extensive hypodense lesion in the submental and submandibular space without peripheral enhancement. The microscopical analysis showed a cystic cavity lined by orthokeratinized stratified squamous epithelium. The cystic capsule was composed of dense fibrous connective tissue containing cutaneous attachments, such as sebaceous and sweat glands. The diagnosis of DC was made. The differential diagnosis of expansive sublingual lesions can be clinically challenging due to the similarity with several lesions frequently observed in this region. Herein, we describe a case of extensive DC arising in the floor of the mouth, presenting clinical, imaging, and microscopical features.


Assuntos
Humanos , Masculino , Adulto , Neoplasias Maxilomandibulares , Cisto Dermoide/patologia , Cisto Dermoide/complicações , Cisto Dermoide/diagnóstico por imagem , Soalho Bucal/lesões
2.
Pediatr Dermatol ; 36(5): 745-746, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31355485

RESUMO

Midline dermoid cysts are uncommon lesions that can lead to severe complications when an intracranial extension exists. We report the cases of two twin sisters referred to surgery for removal of the masses and the intracranial extension. They represent an additional example of familial nasal dermoid cysts, providing further support for a genetic basis for the disorder.


Assuntos
Cisto Dermoide/congênito , Doenças em Gêmeos/congênito , Neoplasias Nasais/congênito , Neoplasias Cutâneas/congênito , Gêmeos Monozigóticos , Cisto Dermoide/patologia , Doenças em Gêmeos/patologia , Feminino , Humanos , Lactente , Neoplasias Nasais/patologia , Neoplasias Cutâneas/patologia
4.
Clin Imaging ; 57: 115-123, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31212220

RESUMO

Mature cystic teratoma (MCT) is a common neoplasm of the ovary that typically contains mature tissues of ectodermal, mesodermal, and endodermal origin. This tumor tends to affect younger women, its presentation ranges from pure cystic mass to complex solid cystic mass, and the detection of intratumoral fat component is the key diagnostic imaging feature. MCT can be associated with various complications and it demonstrates a wide spectrum of imaging findings. Associated complications include rupture, torsion, malignant transformation, and gliomatosis peritonei. MCT may also have unusual imaging features that can lead to misdiagnosis. These features may expand the differential diagnosis to include immature teratoma, monodermal teratoma, mature cystic teratoma with minimal or no fat, and collision tumor. The aim of this article was to highlight and describe the imaging features of unusual ovarian MCT lesions, and the complications associated with ovarian MCT.


Assuntos
Neoplasias Ovarianas/patologia , Teratoma/patologia , Adulto , Transformação Celular Neoplásica/patologia , Cisto Dermoide/patologia , Diagnóstico Diferencial , Feminino , Humanos , Neoplasias Ovarianas/diagnóstico por imagem , Doenças Peritoneais/patologia , Teratoma/diagnóstico por imagem
5.
J Clin Neurosci ; 67: 172-177, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31088770

RESUMO

Intracranial dermoids (ID) are relatively uncommon. They are usually located in the midline or posterior fossa, and present in the first three decades of life. Rupture of IDs are a rare occurrence, and can present with diverse clinical features. They have a characteristic appearance on Computerized Tomography (CT) and Magnetic-Resonance-Imaging (MRI). Here we retrospectively review the clinical features, radiology, treatment and outcomes of ruptured IDs managed in our institute. We did a retrospective review of all the IDs from 2011 to 2017 that presented to us with rupture, or that were diagnosed to have ruptured based on imaging characteristics. Nine patients qualified for our study. The data of all 9 patients was analyzed retrospectively and their demographic details, clinical variations, and radiological features were studied and analyzed. Mode of management and outcome was assessed. Mean age of the patients was 32.1 years (SD 7.65) with male-female ratio of 7:2. Patients presented with either headache or seizures in the majority. Two patients had hydrocephalus requiring shunts. Despite their varied location and clinical features, all lesions showed similar and characteristic radiological features-namely, fat droplets in subarachnoid spaces, hypo-intensity on Susceptibility-Weighted-Imaging (SWI) with chemical shift artifact. Treatment of patients varied from medical management in 4, to cerebrospinal fluid (CSF) diversion in 2 and surgery for the lesion in 3 cases. Ruptured IDs present with a wide array of clinical features. Imaging characteristics are fairly distinct and consistent, which aids in diagnosis. Decision for mode of management has to be decided based on case-by-case basis.


Assuntos
Cistos do Sistema Nervoso Central/patologia , Cisto Dermoide/patologia , Adulto , Cistos do Sistema Nervoso Central/diagnóstico por imagem , Cisto Dermoide/diagnóstico por imagem , Feminino , Humanos , Imagem por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Ruptura Espontânea , Tomografia Computadorizada por Raios X
6.
J Am Anim Hosp Assoc ; 55(4): e55403, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31099609

RESUMO

A 6 mo old male castrated bloodhound-Rhodesian ridgeback mix (case 1) presented for a mass suspected to be a dermoid sinus in the thoracolumbar region, and a 2.5 yr old male castrated Rhodesian ridgeback (case 2) presented for a mass suspected to be a dorsal cervical dermoid sinus. Both dogs underwent single-phase contrast computed tomography (CT) to characterize the extent of the dermoid sinus prior to surgical excision. Soft tissue and bony abnormalities of the vertebral spine associated with the dermoid sinuses were confirmed in both dogs prior to surgery, demonstrating communication with the dura of the spinal cord. Surgical exploration and excision of the dermoid sinus was performed in each dog, including partial laminectomy. Both cases had resolution of the sinus and an uncomplicated recovery. These cases show that single-phase contrast CT was accurate in characterizing the extent of the dermoid sinus without adjunctive tests or more invasive diagnostics. Single-phase contrast CT should be considered as a preoperative method to characterize the extent of dermoid sinuses, avoiding the risks associated with myelography or fistulography and the expense of MRI. This is also the first report of a dermoid sinus in the thoracolumbar region and the first in a bloodhound and Rhodesian ridgeback mix.


Assuntos
Cisto Dermoide/veterinária , Doenças do Cão/diagnóstico , Neoplasias da Coluna Vertebral/veterinária , Tomografia Computadorizada por Raios X/veterinária , Animais , Cisto Dermoide/diagnóstico , Cisto Dermoide/patologia , Cisto Dermoide/cirurgia , Doenças do Cão/patologia , Doenças do Cão/cirurgia , Cães , Laminectomia/veterinária , Masculino , Neoplasias da Coluna Vertebral/diagnóstico , Neoplasias da Coluna Vertebral/patologia
7.
BMJ Case Rep ; 12(4)2019 Apr 24.
Artigo em Inglês | MEDLINE | ID: mdl-31023732

RESUMO

A 4-month-old boy presented with a cystic swelling at the floor of the mouth causing acute airway compromise. The only previous history of note, was a tongue tie release at 3 days old. CT scan suggested a dermoid cyst with extensive floor of mouth abscess. He had an excision of the cyst and drainage of the superimposed abscess and made a good recovery. The histology report revealed a dermoid cyst which is a rare diagnosis in a child, particularly within the oral cavity. Early treatment is required to remove these lesions especially when they cause airway compromise or swallowing difficulties. This is the first case to our knowledge which suggests tongue tie release procedures causes a predisposition to the development of dermoid cysts in the oral cavity.


Assuntos
Abscesso/microbiologia , Transtornos de Deglutição/etiologia , Cisto Dermoide/patologia , Drenagem/métodos , Abscesso/patologia , Doença Aguda , Anquiloglossia/complicações , Anquiloglossia/patologia , Cisto Dermoide/complicações , Cisto Dermoide/diagnóstico por imagem , Cisto Dermoide/cirurgia , Humanos , Lactente , Masculino , Soalho Bucal/patologia , Soalho Bucal/cirurgia , Tomografia Computadorizada por Raios X/métodos , Resultado do Tratamento
8.
Int J Pediatr Otorhinolaryngol ; 122: 89-92, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30991206

RESUMO

OBJECTIVES: To evaluate the use of ultrasound to distinguish between thyroglossal duct cysts (TGDC) and dermoid cysts (DC) for surgical planning. To validate the SIST (septae + irregular wall + solid components = TGDC) scoring system proposed by Oyewumi et al. [1]. METHODS: This was a retrospective chart review of pediatric patients with midline neck masses who presented between the years of 2005 and 2014 and underwent preoperative ultrasound and surgical resection. Two pediatric radiologists blinded to diagnosis reviewed each US for 14 separate characteristics. According to the SIST scoring system, one point was given for each of the following: internal septae, irregular walls, and solid components. RESULTS: 45 patients met inclusion criteria. Final pathologic diagnosis showed 29 patients had TGDC, 16 had DC. The majority of patients with both TGDC and DC earned SIST scores of 0. CONCLUSION: While ultrasound remains a useful part of the work-up of lesions of the head and neck in children, this small retrospective study was not able to validate the previously proposed SIST scoring system None of the parameters discussed in the original paper was found to be a statistically significant determinant of TGDC.


Assuntos
Cisto Dermoide/diagnóstico por imagem , Cisto Tireoglosso/diagnóstico por imagem , Cisto Tireoglosso/cirurgia , Ultrassonografia , Criança , Pré-Escolar , Cisto Dermoide/patologia , Diagnóstico Diferencial , Emolientes , Feminino , Humanos , Lactente , Masculino , Pescoço , Período Pré-Operatório , Estudos Retrospectivos , Método Simples-Cego , Cisto Tireoglosso/patologia
9.
BMJ Case Rep ; 12(3)2019 Mar 31.
Artigo em Inglês | MEDLINE | ID: mdl-30936324

RESUMO

Tubo-ovarian abscesses (TOAs) are inflammatory masses involving the fallopian tube, ovary and occasionally other adjacent pelvic organs. A 32-year-old woman with no significant medical history presented with a chief complaint of lower abdominal pain. Initial CT of the abdomen was suggestive of a colon abscess; however, a repeat CT suggested a TOA. The left ovary was densely adherent to the left pelvic sidewall and the rectosigmoid colon. The content of the ovary was consistent with a dermoid and suspected of superinfection. Pathological examination of the tissue revealed normal ovarian cortical tissue, hair cells, melanin, and epidermal and neural tissue, as well as evidence of a foreign object resembling vegetable matter. The vegetable fibre found in this patient's biopsy was of an unclear aetiology, but probably indicates a perforation of the bowel. Any cause of bowel perforation adjacent to the adnexa can lead to TOA, therefore providing a rational speculation for this case.


Assuntos
Dor Abdominal/etiologia , Abscesso/diagnóstico por imagem , Antibacterianos/uso terapêutico , Cisto Dermoide/patologia , Doenças das Tubas Uterinas/diagnóstico por imagem , Doenças Ovarianas/diagnóstico por imagem , Superinfecção/patologia , Dor Abdominal/diagnóstico por imagem , Dor Abdominal/patologia , Abscesso/patologia , Abscesso/terapia , Adulto , Ampicilina/uso terapêutico , Cisto Dermoide/diagnóstico por imagem , Cisto Dermoide/terapia , Doxiciclina/uso terapêutico , Doenças das Tubas Uterinas/patologia , Doenças das Tubas Uterinas/terapia , Feminino , Humanos , Perfuração Intestinal/patologia , Laparoscopia , Doenças Ovarianas/patologia , Doenças Ovarianas/terapia , Ovariectomia , Ovário/patologia , Sulbactam/uso terapêutico , Superinfecção/tratamento farmacológico , Tomografia Computadorizada por Raios X , Resultado do Tratamento
10.
Mol Genet Genomic Med ; 7(5): e625, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30891959

RESUMO

BACKGROUND: Postzygotic KRAS, HRAS, NRAS, and FGFR1 mutations result in a group of mosaic RASopathies characterized by related developmental anomalies in eye, skin, heart, and brain. These oculocutaneous disorders include oculoectodermal syndrome (OES) encephalo-cranio-cutaneous lipomatosis (ECCL), and Schimmelpenning-Feuerstein-Mims syndrome (SFMS). Here, we report the results of the clinical and molecular characterization of a novel cohort of patients with oculocutaneous mosaic RASopathies. METHODS: Two OES, two ECCL, and two SFMS patients were ascertained in the study. In addition, two subjects with unilateral isolated epibulbar dermoids were also enrolled. Molecular analysis included PCR amplification and Sanger sequencing of KRAS, HRAS, NRAS, and FGFR1 genes in DNA obtained from biopsies (skin/epibulbar dermoids), buccal mucosa, and blood leukocytes. Massive parallel sequencing was employed in two cases with low-level mosaicism. RESULTS: In DNA from biopsies, mosaicism for pathogenic variants, including KRAS p.Ala146Thr in two OES subjects, FGFR1 p.Asn546Lys and KRAS p.Ala146Val in ECCL patients, and KRAS p.Gly12Asp in both SFMS patients, was demonstrated. No mutations were shown in DNA from conjunctival lesions in two subjects with isolated epibubar dermoids. CONCLUSION: Our study allowed the expansion of the clinical spectrum of mosaic RASopathies and supports that mosaicism for recurrent mutations in KRAS and FGFR1 is a commonly involved mechanism in these rare oculocutaneous anomalies.


Assuntos
Cisto Dermoide/genética , Displasia Ectodérmica/genética , Oftalmopatias/genética , Lipomatose/genética , Síndromes Neurocutâneas/genética , Nevo Sebáceo de Jadassohn/genética , Fenótipo , Receptor Tipo 1 de Fator de Crescimento de Fibroblastos/genética , Cisto Dermoide/patologia , Displasia Ectodérmica/patologia , Oftalmopatias/patologia , GTP Fosfo-Hidrolases/genética , Humanos , Lipomatose/patologia , Proteínas de Membrana/genética , Mosaicismo , Síndromes Neurocutâneas/patologia , Nevo Sebáceo de Jadassohn/patologia , Proteínas Proto-Oncogênicas p21(ras)/genética
11.
World Neurosurg ; 127: 15-19, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30872204

RESUMO

BACKGROUND: Intraspinal dermoid tumors are usually rare benign growths that occur as a result of defects during neural tube formation. They make up less than 1% of tumors in the spine and are associated with spinal dysraphisms or sinus tracts. Although rare, malignant transformation into squamous cell carcinoma has been previously reported. Malignant transformation into adenocarcinoma, however, represents a novel phenotypic differentiation pattern that is hitherto undescribed. CASE DESCRIPTION: A 45-year-old woman presented with acute symptoms of cauda equina syndrome. Imaging of the spine revealed a large intradural sacral mass. The lesion was surgically resected with pathology revealing a dermoid tumor with malignant transformation into adenocarcinoma. Metastatic workup revealed no other suspicious lesions. The patient had an uneventful postoperative course, gradually regaining micturition control. CONCLUSIONS: Dermoid tumors, also known as benign cystic teratoma or mature teratoma, are usually benign congenital tumors comprising epithelial cells that arise from displaced embryonic ectoderm and mesoderm during neural tube formation. Although extremely rare, malignant transformation into squamous cell carcinoma has been reported. This case represents the first report of an intraspinal dermoid tumor transforming into adenocarcinoma. A comprehensive histopathologic analysis is key to identifying the lesion and guiding postsurgical management.


Assuntos
Adenocarcinoma/complicações , Síndrome da Cauda Equina/complicações , Cauda Equina/patologia , Cisto Dermoide/complicações , Neoplasias do Sistema Nervoso Periférico/complicações , Neoplasias da Coluna Vertebral/complicações , Adenocarcinoma/patologia , Síndrome da Cauda Equina/patologia , Cisto Dermoide/patologia , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasias do Sistema Nervoso Periférico/patologia , Neoplasias da Coluna Vertebral/patologia
14.
Clin Imaging ; 56: 47-51, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30878712

RESUMO

Dermoid cysts, or mature cystic teratomas, are complicated by malignant degeneration in only 1-2% of cases. Rarely, dermoid cysts result in complications of small bowel obstruction or entero-ovarian fistula formation. In the current report we present the case of a 59-year-old female with a known dermoid cyst who presented with leukocytosis and was discovered to have a small bowel obstruction at the level of an ileo-ovarian fistula. The patient was taken to the operating room and was treated with total abdominal hysterectomy, bilateral salpingo-oopherectomy, and short segment small bowel resection. Review of the surgical pathology revealed areas of malignant degeneration within the dermoid cyst to squamous cell carcinoma. To our knowledge, this is only the second reported case of an ovarian dermoid cyst complicated by small bowel obstruction, entero-ovarian fistula formation, and malignant degeneration.


Assuntos
Carcinoma de Células Escamosas , Cisto Dermoide/complicações , Fístula/etiologia , Obstrução Intestinal/etiologia , Intestino Delgado/patologia , Neoplasias Ovarianas/complicações , Ovário/patologia , Teratoma/complicações , Carcinoma de Células Escamosas/cirurgia , Coristoma/complicações , Coristoma/patologia , Coristoma/cirurgia , Cisto Dermoide/patologia , Cisto Dermoide/cirurgia , Feminino , Fístula/cirurgia , Humanos , Histerectomia , Obstrução Intestinal/cirurgia , Intestino Delgado/cirurgia , Pessoa de Meia-Idade , Neoplasias Ovarianas/patologia , Neoplasias Ovarianas/cirurgia , Ovário/cirurgia , Teratoma/patologia , Teratoma/cirurgia
15.
Otolaryngol Head Neck Surg ; 160(6): 1111-1117, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-30717638

RESUMO

OBJECTIVE: To assess clinical evaluation, ultrasound, and previously published predictive score at preoperatively diagnosing midline neck masses and demographic or clinical associations that aid in differentiation of thyroglossal duct and dermoid cysts. STUDY DESIGN: Retrospective chart review. SETTING: Tertiary care children's hospital. SUBJECTS: Patients <18 years undergoing primary midline neck mass surgery with histopathologic diagnosis of thyroglossal duct or dermoid cyst who had preoperative ultrasound performed were included. METHODS: An electronic medical record query generated 142 patients whose histopathologic diagnosis was thyroglossal duct cysts (TGDCs) or dermoid cysts (DCs). Charts were reviewed for demographic and clinical features. A radiologist blindly reviewed patients' ultrasounds for SIST (septae + irregular walls + solid components = thyroglossal) score components. Each patient received 3 preoperative diagnoses: clinical, ultrasound, and SIST. Statistical analyses were conducted to determine association of demographic, clinical, or radiographic variables with diagnoses. Specificity, sensitivity, and predictive values were evaluated for each candidate diagnosis. RESULTS: There were 83 TGDCs and 59 DCs. Tenderness, infection history, depth relative to strap muscles, and SIST components were more common among TGDCs. Sensitivity and positive and negative predictive values surpassed 63% for each diagnostic modality. SIST score outperformed other diagnostic modalities with sensitivity, positive predictive value, and negative predictive value of 84%, 91%, and 81%, respectively. Clinical and ultrasound assessments were largely inconclusive for dermoid cysts, but SIST correctly identified 89% of DCs. CONCLUSION: SIST score was the most accurate predictor of pediatric midline neck masses. Clinical and radiographic findings may help guide preoperative diagnosis, although further evaluation is required to develop more efficacious diagnostic tools.


Assuntos
Cisto Dermoide/diagnóstico por imagem , Neoplasias de Cabeça e Pescoço/diagnóstico por imagem , Cisto Tireoglosso/diagnóstico por imagem , Criança , Pré-Escolar , Cisto Dermoide/patologia , Cisto Dermoide/cirurgia , Feminino , Neoplasias de Cabeça e Pescoço/patologia , Neoplasias de Cabeça e Pescoço/cirurgia , Humanos , Lactente , Masculino , Valor Preditivo dos Testes , Estudos Retrospectivos , Cisto Tireoglosso/patologia , Cisto Tireoglosso/cirurgia , Ultrassonografia
17.
Neuroradiol J ; 32(2): 92-97, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30604653

RESUMO

Intracranial dermoid and epidermoid cysts are usually considered to be two different entities in the radiological and surgical literature. Epidermoid cysts are classically off midline in location, isointense to cerebrospinal fluid on T1 and T2-weighted images and have restricted diffusion, whereas dermoid cysts are classically midline in location, have T1-hyperintense regions due to the presence of fat and show facilitated diffusion. We report a case of radiological epidermoid cyst in baseline imaging, which evolved into a radiological dermoid cyst over time, and explain this unique occurrence with a review of the embryology and histopathogenesis of these cysts.


Assuntos
Neoplasias Encefálicas/diagnóstico por imagem , Neoplasias Encefálicas/embriologia , Cisto Dermoide/diagnóstico por imagem , Cisto Dermoide/embriologia , Cisto Epidérmico/diagnóstico por imagem , Cisto Epidérmico/embriologia , Neoplasias Encefálicas/patologia , Neoplasias Encefálicas/cirurgia , Cisto Dermoide/patologia , Cisto Dermoide/cirurgia , Cisto Epidérmico/patologia , Cisto Epidérmico/cirurgia , Humanos , Imagem por Ressonância Magnética , Masculino , Ruptura Espontânea , Tomografia Computadorizada por Raios X , Adulto Jovem
18.
J Craniofac Surg ; 30(2): 514-515, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30676442

RESUMO

BACKGROUND: Dermoid cysts are squamous epithelium-lined sacs that result from abnormal migration of ectodermal cells. They are typically superficial and present in children. This study reviews a rare patient with a congenital dermoid cyst occurring as a superolateral intraorbital and extraconal mas. METHOD: Clinical report and review of the literature. RESULTS: A 27-year-old male presented with progressive left hypoglobus, proptosis, and diplopia. On computed tomography, a 2.0 × 2.1 × 1.1 cm well circumscribed mass centered on, and extended into, the frontozygomatic suture with smooth remodeling of the frontal bone. Magnetic resonance imaging showed heterogeneous T1 and T2 hyperintensity with hypointensity on fat suppression. A dermoid cyst originating from the frontozygomatic suture was suspected. Excision was performed through a left orbitocranial approach with a lateral orbitotomy through an upper eyelid crease incision. The mass occurred in the superior-lateral portion of the left orbit and originated from the intraorbital surface of the zygomaticofrontal suture line with significant bony remodeling without osseous transgression. The mass was removed completely including the lateral portion of the zygomaticofrontal suture. Pathologic examination was consistent with a dermoid cyst. Postoperative examination revealed resolution of his presenting headaches and diplopia. CONCLUSION: Congenital dermoid cysts occurring within the craniofacial region occur most commonly in the lateral orbit involving the superficial surface of the frontozygomatic suture. This patient represents the rare occurrence of a dermoid cyst originating from the deep surface of the frontozygomatic suture, resulting in delayed presentation and orbital symptoms of hypoglobus and diplopia. Definitive treatment remains complete surgical excision.


Assuntos
Suturas Cranianas/patologia , Cisto Dermoide/diagnóstico , Neoplasias Orbitárias/diagnóstico , Adulto , Cisto Dermoide/congênito , Cisto Dermoide/patologia , Cisto Dermoide/cirurgia , Humanos , Masculino , Invasividade Neoplásica , Neoplasias Orbitárias/congênito , Neoplasias Orbitárias/patologia , Neoplasias Orbitárias/cirurgia
20.
Ophthalmic Epidemiol ; 26(2): 117-120, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-30260262

RESUMO

PURPOSE: To report the incidence, clinical findings, and surgical outcomes of periocular dermoid cysts diagnosed among children over a 20-year period. METHODS: All patients ≤5 years of age, who were diagnosed with a periocular dermoid cyst in Olmsted County, Minnesota from 1986 to 2005 were reviewed to determine the population incidence, clinical presentation, and management outcomes. RESULTS: A total of 54 children were diagnosed with a periocular dermoid cyst during the 20-year period, yielding a birth incidence of 1 in 638 live births. The mean age at diagnosis was 12 months (range, 1 month-60 months) and 29 (53.7%) were female. A total of 44 cysts (81.5%) occurred in the superotemporal orbital rim, 6 (11.1%) in the superonasal orbital rim, 3 (5.6%) in other periocular areas, and one (1.9%) within the orbit. A total of 34 (63%) children had an ophthalmic exam, all without amblyopia or other ocular sequelae. A total of 48 (88.9%) patients underwent surgical excision with 5 (10.4%) having documented intra-operative cyst rupture, none of whom had post-operative complications. Two (4.2%) other patients were, however, noted to have lesion recurrence following surgical intervention. CONCLUSIONS: Periocular dermoid cysts occur in approximately 1 in 650 live births and most commonly occur in the superotemporal region of children aged 1 year or less. Ocular sequelae are rare and surgical excision often yields excellent results.


Assuntos
Cisto Dermoide , Neoplasias Palpebrais , Neoplasias Orbitárias , Pré-Escolar , Cisto Dermoide/epidemiologia , Cisto Dermoide/patologia , Cisto Dermoide/cirurgia , Neoplasias Palpebrais/epidemiologia , Neoplasias Palpebrais/patologia , Neoplasias Palpebrais/cirurgia , Feminino , Humanos , Incidência , Lactente , Masculino , Minnesota/epidemiologia , Neoplasias Orbitárias/epidemiologia , Neoplasias Orbitárias/patologia , Neoplasias Orbitárias/cirurgia
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